CN216395061U - All-wrapping mouse hind limb ultraviolet radiation fixator - Google Patents
All-wrapping mouse hind limb ultraviolet radiation fixator Download PDFInfo
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- CN216395061U CN216395061U CN202122149783.8U CN202122149783U CN216395061U CN 216395061 U CN216395061 U CN 216395061U CN 202122149783 U CN202122149783 U CN 202122149783U CN 216395061 U CN216395061 U CN 216395061U
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Abstract
The utility model discloses a full-wrapping mouse hind limb ultraviolet radiation fixator which comprises an outer cylinder rotary shielding mechanism, an inner cylinder fixing mechanism and a push rod fixing mechanism. The utility model realizes a full-wrapping mouse hindlimb ultraviolet radiation fixator by arranging the mutual matching of the outer cylinder rotating shielding mechanism, the inner cylinder fixing mechanism and the push rod fixing mechanism, and has the following beneficial effects: the mouse fixer is fully wrapped, so that the influence of ultraviolet radiation on other parts is avoided; the instrument does not contact the head of a mouse in the whole process, so that the risk of biting is avoided; the mice do not need to be anesthetized, so that the damage of repeated anesthesia to the mice is reduced; this technical scheme is high-efficient safe, and is easy and simple to handle, provides convenience for the development of relevant experiment, and this technical scheme both can accomplish bilateral hind limb and radiate again arbitrary unilateral hind limb, and the existence of transparent strip makes can observe the mouse state in real time when fixed mouse in addition.
Description
Technical Field
The utility model relates to the technical field of animal experiment instruments, in particular to a full-wrapping mouse hindlimb ultraviolet radiation fixator.
Background
The incidence of skin cancer has increased year by year, and it is currently widely believed that ultraviolet exposure is closely related to skin cancer. The research on the generation and transfer mechanism of ultraviolet rays and various skin malignant tumors mostly needs to establish a mouse hind limb local ultraviolet radiation model. The establishment of the model has the following requirements: first, to investigate the local effect, local irradiation conditions must be satisfied, and exposure of other parts than the irradiation part should be minimized. Secondly, in order to ensure that the dose of the radiation is uniform and stable, the position and the posture of the mouse are required to be fixed. In addition, chronic radiation modeling requires that a dose of ultraviolet radiation be received daily for a number of consecutive days. However, there is no operating device that satisfies the above conditions. The current common method is to anaesthetize or fix the mouse on a non-special apparatus, shield the mouse with black cloth or paper sheets, cardboard and the like, and radiate the mouse after erecting an ultraviolet lamp above the black cloth or paper sheets, cardboard and the like. However, this approach has a number of problems:
1. certain experimental modeling needs to be carried out continuously for several days, a certain dose of ultraviolet radiation is received every day, repeated anesthesia is carried out, the normal physiological state of a mouse is seriously influenced, and the accuracy of an experimental result is influenced;
2. the shielding is difficult to avoid the conditions of insufficient shielding and exposure of other parts by using materials such as cloth, paper boards and the like. For example, the exposure of eyes and other parts may cause blindness of mice, and the experimental result is influenced;
3. in the traditional mode, if anesthesia is not performed and binding and fixing are directly performed, the risk of being bitten by a mouse is increased;
4. the operation of using a non-special appliance as a temporary fixing frame is complex, time-consuming and labor-consuming;
in view of the above problems, no effective solution has been proposed.
SUMMERY OF THE UTILITY MODEL
The utility model aims to provide a fully-wrapped mouse hindlimb ultraviolet radiation fixator to solve the problems in the background art.
In order to achieve the purpose, the utility model provides the following technical scheme: a fully-wrapped mouse hind limb ultraviolet radiation fixator comprises an outer cylinder rotating shielding mechanism, an inner cylinder fixing mechanism and a push rod fixing mechanism, wherein the inner cylinder fixing mechanism is arranged inside the outer cylinder rotating shielding mechanism;
the outer cylinder rotary shielding mechanism comprises an outer cylinder main body, wherein a second crack and a first crack are respectively formed in the left side and the right side of the top of the front surface of the outer cylinder main body, and an annular bulge is fixedly connected to the inner wall of the outer cylinder main body;
the inner cylinder fixing mechanism comprises an inner cylinder main body arranged in the outer cylinder main body, the left side and the right side of the bottom of the front surface of the inner cylinder main body are respectively provided with a fourth slit and a third slit, the rear side of the inner cylinder main body is provided with a through slit, the positions of the side surface of the inner wall of the inner cylinder main body, corresponding to the third slit and the fourth slit, are respectively and fixedly connected with a first inclined fixing plate and a second inclined fixing plate, and the positions of the inner cylinder main body, corresponding to the two side edges of the through slit, are respectively and fixedly connected with a first transparent strip and a second transparent strip;
the push rod fixing mechanism comprises a cross rod arranged inside the inner barrel main body, the top of the cross rod and the left side of the bottom of the cross rod are both connected with an elastic arm, one side of the elastic arm, away from the cross rod, is fixedly connected with a sawtooth pad, the right end of the cross rod is provided with a funnel through a screw, and air holes are formed in the side face of the funnel.
Preferably, the outer cylinder body is matched with the inner cylinder body, and the surface of the inner cylinder body is contacted with the inner wall of the outer cylinder body.
Preferably, the top end of the outer cylinder main body is in an open state, and the bottom end of the outer cylinder main body is in a closed state.
Preferably, the inner cylinder main body is of a hollow tubular structure, and the top end and the bottom of the inner cylinder main body are both in an open state.
Compared with the prior art, the utility model has the following beneficial effects:
the utility model realizes a full-wrapping mouse hindlimb ultraviolet radiation fixator by arranging the mutual matching of the outer cylinder rotating shielding mechanism, the inner cylinder fixing mechanism and the push rod fixing mechanism, and has the following beneficial effects:
1. the mouse fixer is fully wrapped, so that the influence of ultraviolet radiation on other parts is avoided;
2. the instrument does not contact the head of a mouse in the whole process, so that the risk of biting is avoided;
3. the mice do not need to be anesthetized, so that the damage of repeated anesthesia to the mice is reduced;
4. the technical scheme is efficient and safe, is simple and convenient to operate, and provides convenience for development of related experiments;
5. according to the technical scheme, the radiation of both lateral hind limbs and any single lateral hind limb can be completed, and the state of the mouse can be observed in real time when the mouse is fixed due to the transparent strip.
Drawings
FIG. 1 is a schematic structural diagram of a perspective view of a rotary shielding mechanism of an outer cylinder according to the present invention;
FIG. 2 is a schematic structural view of a perspective view of an inner cylinder fixing mechanism according to the present invention;
FIG. 3 is a schematic structural diagram of a top view of the inner cylinder fixing mechanism of the present invention;
FIG. 4 is a schematic structural view of a front view of the push rod securing mechanism of the present invention;
fig. 5 is a schematic structural view of a front view of a base of the present invention.
In the figure: the outer cylinder rotating shielding mechanism comprises a 1 outer cylinder rotating shielding mechanism, a 101 outer cylinder main body, a 102 first crack, a 103 second crack, a 104 annular bulge, a 2 inner cylinder fixing mechanism, a 201 inner cylinder main body, a 202 third crack, a 203 fourth crack and a 204 through a crack, a 205 first inclined fixing plate, a 206 second inclined fixing plate, a 207 first transparent strip, a 208 second transparent strip, a 3 push rod fixing mechanism, a 301 cross rod, a 302 elastic arm, a 303 sawtooth pad, 304 screws, a 305 funnel and 306 air holes.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Referring to fig. 1-5, a fully-wrapped mouse hind limb ultraviolet radiation fixator comprises an outer cylinder rotary shielding mechanism 1, an inner cylinder fixing mechanism 2 and a push rod fixing mechanism 3, wherein the inner cylinder fixing mechanism 2 is arranged inside the outer cylinder rotary shielding mechanism 1, and the push rod fixing mechanism 3 is arranged inside the inner cylinder fixing mechanism 2.
The outer cylinder rotary shielding mechanism 1 comprises an outer cylinder main body 101, the top end of the outer cylinder main body 101 is in an open state, the bottom end of the outer cylinder main body 101 is in a closed state, the left side and the right side of the top of the front surface of the outer cylinder main body 101 are respectively provided with a second slit 103 and a first slit 102, and the inner wall of the outer cylinder main body 101 is fixedly connected with an annular bulge 104.
The inner cylinder fixing mechanism 2 comprises an inner cylinder main body 201 arranged inside the outer cylinder main body 101, the outer cylinder main body 101 is matched with the inner cylinder main body 201, the surface of the inner cylinder main body 201 is contacted with the inner wall of the outer cylinder main body 101, the inner cylinder main body 201 is of a hollow tubular structure, the top end and the bottom of the inner cylinder main body 201 are both in an open state, the left side and the right side of the front bottom of the inner cylinder main body 201 are respectively provided with a fourth crack 203 and a third crack 202, the rear side of the inner cylinder main body 201 is provided with a through crack 204, the positions of the inner wall side surface of the inner cylinder main body 201 corresponding to the third crack 202 and the fourth crack 203 are respectively and fixedly connected with a first inclined fixing plate 205 and a second inclined fixing plate 206, the positions of the inner cylinder main body 201 corresponding to the two sides through the crack 204 are respectively and fixedly connected with a first transparent strip 207 and a second transparent strip 208, the inner cylinder fixing mechanism 2 is completely matched with the outer cylinder rotary shielding mechanism 1, the outer cylinder rotary shielding mechanism 1 can be just sleeved outside the inner cylinder fixing mechanism 2, and can rotate freely, when one end D of the inner cylinder fixing mechanism 2 is pushed to the annular bulge 104 of the outer cylinder rotating shielding mechanism 1, can be clamped and can not be pushed forward, at the moment, the other end C just coincides with one end A of the outer cylinder rotary shielding mechanism 1, in addition, the third crack 202 and the fourth crack 203 of the inner cylinder fixing mechanism 2 are completely matched with the first crack 102 and the second crack 103 of the outer cylinder rotary shielding mechanism 1, when the D-end is advanced into the annular protrusion 104, the first slit 102 combines with the third slit 202, the second slit 103 combines with the fourth slit 203, forming exactly two circular holes, when the first slit 102 combines with the fourth slit 203, or the second slit 103 and the third slit 202 are combined to form a circular hole, the original circular hole on the other side is blocked and closed, and the inner cylinder fixing mechanism 2 passing through the slit 204 and the first transparent strip 207 and the second transparent strip 208 on the two sides can be completely blocked by the outer cylinder rotating blocking mechanism 1.
The push rod fixing mechanism 3 comprises a cross rod 301 arranged inside the inner cylinder main body 201, the top and the left side of the bottom of the cross rod 301 are both connected with an elastic arm 302, one side of the elastic arm 302 far away from the cross rod 301 is fixedly connected with a sawtooth pad 303, the sawtooth pad 303 is made of rubber, the right end of the cross rod 301 is provided with a funnel 305 through a screw 304, the side surface of the funnel 305 is provided with a vent hole 306, the push rod fixing mechanism 3 is completely matched with the inner cylinder fixing mechanism 2, when the two elastic arms 302 are pinched, the push rod fixing mechanism 3 can freely slide in the inner cylinder fixing mechanism 2, when the two elastic arms 302 are loosened, the two sawtooth pads 303 are propped against the inner side wall of the inner cylinder main body 201 and cannot move, in the technical scheme, the first transparent strip 207 and the second transparent strip 208 on the side wall of the inner cylinder main body 201 are arranged, all other devices are black, the used materials include but are not limited to acrylic plates, metal and wood materials and the like, the whole fixator is matched with a base to be used together, the base is provided with semi-cylindrical depressions for accommodating a plurality of full-wrapping mouse hind limb fixators, and the depressions are completely matched with the full-wrapping mouse hind limb fixators.
When the device is used, if two hind limbs of a mouse need to be radiated, the tail of the mouse is lifted, the mouse is pulled into the inner cylinder from the C end of the inner cylinder main body 201 along the crack and is pulled to the D end of the inner cylinder main body 201 until the tail is clamped by the baffle, the forceps-shaped structure of the push rod fixing mechanism 3 is pinched by the other hand, the end of the funnel 305 is sent into the inner cylinder main body 201 along the A end of the outer cylinder main body 101 and is pushed forwards, meanwhile, the condition of the mouse is observed from the transparent layer, the mouse is pushed to be completely limited to release the push rod fixing mechanism 3, the mouse is completely fixed at the moment, two hind limbs of the mouse are placed in the third crack 202 and the fourth crack 203 of the crack, the push rod is properly adjusted, the first crack 102 and the second crack 103 on the outer cylinder main body 101 are involuted with the third crack 202 and the fourth crack 203 of the inner cylinder main body 201 and are pushed forwards until the two hind limbs of the mouse are mutually shielded, only the two hind limbs of the mouse in the mouse pass through the two crack holes, except for the two hind limbs, the rest parts of the mouse are covered by the wrapped parts, and the light transmission parts of the cracks of the two cylinders are mutually shielded, so that the complete wrapping is achieved.
If only the right hind limb of the mouse needs to be radiated, the tail of the mouse is lifted, the mouse is pulled into the inner cylinder main body 201 from the C end along the crack, the D end of the inner cylinder is pulled to the D end until the right hind limb is clamped by the baffle, the pincer-shaped structure of the push rod fixing mechanism 3 is pinched by the other hand, the end of the funnel 305 is sent into the inner cylinder main body 201 along the A end of the outer cylinder main body and is pushed forwards, meanwhile, the situation of the mouse is observed from the transparent layer, the push rod fixing mechanism 3 is loosened until the movement of the mouse is completely limited, the mouse is completely fixed at the moment, the right hind limb of the mouse is pulled out and is placed in the fourth crack 203, the push rod is properly adjusted, if the first crack 102 of the spoke outer cylinder main body 101 is matched with the fourth crack 203 of the inner cylinder main body, the two cracks are mutually shielded, only the right hind limb of the mouse passes through the crack hole, at the rest parts of the mouse are all wrapped and the light transmission parts of the two cracks are mutually shielded, complete wrapping is achieved.
Similarly, if only the left hind limb of the mouse needs to be radiated, the tail of the mouse is lifted, the mouse is pulled into the inner cylinder main body 201 from the C end along the crack, the D end of the inner cylinder is pulled until being clamped by the baffle, the forceps-shaped structure of the push rod fixing mechanism 3 is pinched by the other hand, the end of the funnel 305 is sent into the inner cylinder along the A end of the outer cylinder main body 101 and is pushed forwards, meanwhile, the condition of the mouse is observed from the transparent layer, and the push rod fixing device is pushed to be completely limited by the movement of the mouse to loosen. At the moment, the mouse is completely fixed, the right hind limb of the mouse is pulled out and placed in the third crack 202, the push rod is properly adjusted, if the second crack 103 of the outer cylinder main body 101 is matched with the third crack 202 of the inner cylinder main body 201, then the push rod is pushed forwards until the two cracks are mutually shielded, only the right hind limb of the mouse in the two cracks is left to penetrate through the crack hole, at the moment, the rest parts of the mouse except the right hind limb are covered by the package, and light transmitting parts of the cracks of the two cylinders are mutually shielded, so that the complete package is achieved.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the utility model, the scope of which is defined in the appended claims and their equivalents.
Claims (4)
1. The utility model provides a wrap nature mouse hind limb ultraviolet radiation fixer entirely, includes that the urceolus is rotatory to be sheltered from mechanism (1), inner tube fixed establishment (2) and push rod fixed establishment (3), its characterized in that: the inner cylinder fixing mechanism (2) is arranged inside the outer cylinder rotary shielding mechanism (1), and the push rod fixing mechanism (3) is arranged inside the inner cylinder fixing mechanism (2);
the outer cylinder rotary shielding mechanism (1) comprises an outer cylinder main body (101), wherein the left side and the right side of the top of the front surface of the outer cylinder main body (101) are respectively provided with a second crack (103) and a first crack (102), and the inner wall of the outer cylinder main body (101) is fixedly connected with an annular bulge (104);
the inner cylinder fixing mechanism (2) comprises an inner cylinder main body (201) arranged inside the outer cylinder main body (101), the left side and the right side of the bottom of the front surface of the inner cylinder main body (201) are respectively provided with a fourth crack (203) and a third crack (202), the rear side of the inner cylinder main body (201) is provided with a through crack (204), the side surface of the inner wall of the inner cylinder main body (201) corresponding to the third crack (202) and the fourth crack (203) is respectively and fixedly connected with a first inclined fixing plate (205) and a second inclined fixing plate (206), and the inner cylinder main body (201) corresponding to the positions of the two side edges of the through crack (204) is respectively and fixedly connected with a first transparent strip (207) and a second transparent strip (208);
push rod fixed establishment (3) is including setting up horizontal pole (301) in inner tube main part (201) inside, horizontal pole (301) top all is connected with elastic arm (302) with the left side of bottom, one side fixedly connected with sawtooth pad (303) of horizontal pole (301) are kept away from in elastic arm (302), funnel (305) are installed through screw (304) to the right-hand member of horizontal pole (301), bleeder vent (306) have been seted up to the side of funnel (305).
2. The fully encapsulated mouse hindlimb uv radiation fixator of claim 1 wherein: the outer cylinder main body (101) is matched with the inner cylinder main body (201), and the surface of the inner cylinder main body (201) is in contact with the inner wall of the outer cylinder main body (101).
3. The fully encapsulated mouse hindlimb uv radiation fixator of claim 2, wherein: the top of urceolus main part (101) is the open mode, the bottom of urceolus main part (101) is the closure state.
4. The fully encapsulated mouse hindlimb uv radiation fixator of claim 3, wherein: the inner cylinder main body (201) is of a hollow tubular structure, and the top end and the bottom of the inner cylinder main body (201) are both in a open state.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202122149783.8U CN216395061U (en) | 2021-09-07 | 2021-09-07 | All-wrapping mouse hind limb ultraviolet radiation fixator |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202122149783.8U CN216395061U (en) | 2021-09-07 | 2021-09-07 | All-wrapping mouse hind limb ultraviolet radiation fixator |
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| CN216395061U true CN216395061U (en) | 2022-04-29 |
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| CN202122149783.8U Active CN216395061U (en) | 2021-09-07 | 2021-09-07 | All-wrapping mouse hind limb ultraviolet radiation fixator |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113663227A (en) * | 2021-09-07 | 2021-11-19 | 华东医院 | All-wrapping mouse hind limb ultraviolet radiation fixator |
| CN113663227B (en) * | 2021-09-07 | 2024-05-31 | 华东医院 | Full-wrapping mouse hind limb ultraviolet radiation fixer |
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2021
- 2021-09-07 CN CN202122149783.8U patent/CN216395061U/en active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113663227A (en) * | 2021-09-07 | 2021-11-19 | 华东医院 | All-wrapping mouse hind limb ultraviolet radiation fixator |
| CN113663227B (en) * | 2021-09-07 | 2024-05-31 | 华东医院 | Full-wrapping mouse hind limb ultraviolet radiation fixer |
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