CN216155832U - Continuous racking machine for nucleic acid extraction reagent - Google Patents

Abstract

The utility model discloses a continuous racking machine for a nucleic acid extraction reagent, which relates to the technical field of nucleic acid detection, and particularly relates to a continuous racking machine for a nucleic acid extraction reagent. Through the matching arrangement of the linear guide rail, the tray, the pore plate and the dropper assembly, the nucleic acid extraction reagent continuous racking machine has the effect that reagents can be respectively racked into a large number of nucleic acid extraction reagents at a time so as to improve the efficiency, and through the matching arrangement of the dropper assembly, the dropper pressing plate and the dropper air cylinder, the nucleic acid extraction reagent continuous racking machine has the effect that the absorption of a large number of reagents can be completed through a simple control structure so as to save the cost.

Description

Continuous racking machine for nucleic acid extraction reagent

Technical Field

The utility model relates to the technical field of nucleic acid detection, in particular to a continuous racking machine for a nucleic acid extraction reagent.

Background

The nucleic acid extraction reagent has the function of extracting nucleic acid in cells, common reagents for nucleic acid extraction comprise guanidine isothiocyanate, guanidine hydrochloride, sodium lauryl sarcosine and the like, the principle of each reagent in the nucleic acid extraction process is different, but the using method is that the reagents are added into a detection sample and fully react, and then the detection sample is further purified.

However, the existing nucleic acid extraction reagent has some defects in the process of subpackaging into nucleic acid sample test tubes, on one hand, the efficiency is low because the reagent can only be subpackaged into a small amount of nucleic acid extraction reagent at a time, and on the other hand, the cost is high because the control structure for sucking the reagent is too complex.

SUMMERY OF THE UTILITY MODEL

Technical problem to be solved

Aiming at the defects of the prior art, the utility model provides a continuous racking machine for nucleic acid extraction reagents, which solves the problems in the background technology.

(II) technical scheme

In order to achieve the purpose, the utility model is realized by the following technical scheme: a continuous racking machine for nucleic acid extraction reagents comprises a racking machine bottom plate, wherein a linear guide rail is fixedly connected to the upper surface of the racking machine bottom plate, a tray is movably connected to the upper portion of the linear guide rail, a pore plate is detachably connected to the upper portion of the tray, nucleic acid sample reagent tubes are inserted into the pore plate, a stand column optical axis is fixedly connected to the front portion and the rear portion of the linear guide rail, a top plate is fixedly connected to the upper portion of the stand column optical axis, a lifting cylinder is fixedly connected to the middle of the top plate, a linear bearing is slidably connected to the outer surface of the stand column optical axis, a floating plate is fixedly connected between the linear bearings, a dropper assembly is fixedly connected to the lower surface of the floating plate and comprises a dropper frame, a unit dropper is fixedly connected to the lower portion of the dropper frame, a connecting shaft is connected to the upper end of the unit dropper in a threaded manner, a rubber nipple is sleeved on the upper portion of the connecting shaft, a burette pressing plate is movably connected above the burette frame, burette air cylinders are fixedly connected to two sides of the floating plate, and an electromagnet is fixedly connected to one side, close to an optical axis of the stand column, of the bottom plate of the racking machine.

Preferably, the burette pressure plate is in clearance fit with the burette frame, and two sides of the burette pressure plate are connected with the burette cylinder through floating joints.

Preferably, a square groove is formed in the upper portion of the tray, a chamfer is formed in the upper portion of the square groove, the square groove is in clearance fit with the pore plate, and the depth of the square groove is smaller than the height of the pore plate.

Preferably, the number of the unit burettes is the same as that of the nucleic acid sample reagent tubes, the unit burettes are in one-to-one correspondence with the nucleic acid sample reagent tubes, and a space is arranged between the unit burettes and the nucleic acid sample reagent tubes.

Preferably, the tray is made of metal iron, waist-shaped holes are formed in two sides of the electromagnet, and the electromagnet is fixedly connected with a bottom plate of the racking machine through screws.

Preferably, the connection position of the connecting shaft and the unit dropper is sealed, the connection position of the nipple and the connecting shaft is sealed, and air holes are formed in the periphery of the dropper frame.

(III) advantageous effects

The utility model provides a continuous racking machine for nucleic acid extraction reagents, which has the following beneficial effects:

1. the nucleic acid extraction reagent continuous racking machine has the advantages that through the matching arrangement of the linear guide rail, the tray, the pore plate and the dropper assembly, the nucleic acid extraction reagent continuous racking machine has the effect that reagents can be racked into a large number of nucleic acid extraction reagents at a single time, so that the efficiency is improved, the pore plate can slide to the position under the dropper assembly and be fixed through the matching of the linear guide rail and the tray, the hole positions of the pore plate correspond to the positions of the unit droppers of the dropper assembly one by one, and further, all the nucleic acid extraction reagents can be racked into the pore plate at a single time, so that the efficiency is improved.

2. This nucleic acid extraction reagent continuous racking machine, through the burette assembly, the cooperation setting of burette clamp plate and burette cylinder, make this nucleic acid extraction reagent continuous racking machine possess and can accomplish the absorption of a large amount of reagents and then practice thrift the effect of cost through simple control structure, the burette clamp plate can reciprocate in burette assembly top through the effect of burette cylinder, extrude all nipple of rubber or release when the burette clamp plate reciprocates, and then realize that all unit burettes absorb reagent or discharge reagent simultaneously, simple structure and steerable a large amount of unit burette absorb or discharge reagent.

Drawings

FIG. 1 is a schematic perspective view of the present invention;

FIG. 2 is a schematic left side view of the present invention;

FIG. 3 is a schematic diagram of a partially exploded view of the present invention;

fig. 4 is a schematic structural view of a cross-sectional view of the present invention.

In the figure: 1. a bottom plate of the subpackaging machine; 2. a linear guide rail; 3. a tray; 4. an orifice plate; 5. a nucleic acid sample reagent tube; 6. an upright post optical axis; 7. a top plate; 8. a lifting cylinder; 9. a linear bearing; 10. a floating plate; 11. a dropper assembly; 1101. a dropper frame; 1102. a unit dropper; 1103. a connecting shaft; 1104. a nipple; 12. a dropper pressing plate; 13. a dropper cylinder; 14. an electromagnet.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments.

Referring to fig. 1 to 4, the present invention provides a technical solution: a continuous racking machine for nucleic acid extraction reagents comprises a racking machine bottom plate 1, wherein a linear guide rail 2 is fixedly connected to the upper surface of the racking machine bottom plate 1, a tray 3 is movably connected to the upper side of the linear guide rail 2, a pore plate 4 is detachably connected to the upper side of the tray 3, a square groove is formed in the upper side of the tray 3, a chamfer is formed in the upper side of the square groove, the square groove is in clearance fit with the pore plate 4, the depth of the square groove is smaller than the height of the pore plate 4, nucleic acid sample reagent tubes 5 are inserted into the pore plate 4, the number of unit dropper 1102 is equal to that of the nucleic acid sample reagent tubes 5, the unit dropper 1102 and the nucleic acid sample reagent tubes 5 are in one-to-one correspondence from top to bottom, a gap is formed between the unit dropper 1102 and the nucleic acid sample reagent tubes 5, a column optical axis 6 is fixedly connected to the front and back of the linear guide rail 2, a top plate 7 is fixedly connected to the upper side of the column optical axis 6, a lifting cylinder 8 is fixedly connected to the middle of the top plate 7, and a linear bearing 9 is slidably connected to the outer surface of the column optical axis 6, a floating plate 10 is fixedly connected between the linear bearings 9, a dropper assembly 11 is fixedly connected to the lower surface of the floating plate 10, the dropper assembly 11 comprises a dropper frame 1101, a unit dropper 1102 is fixedly connected to the lower portion of the dropper frame 1101, a connecting shaft 1103 is in threaded connection with the upper end of the unit dropper 1102, a rubber nipple 1104 is sleeved on the upper portion of the connecting shaft 1103 in a sleeved mode, the connecting portion of the connecting shaft 1103 and the unit dropper 1102 is sealed, the connecting portion of the rubber nipple 1104 and the connecting shaft 1103 is sealed, air holes are formed in the periphery of the dropper frame 1101, the orifice plate 4 can slide to the position under the dropper assembly 11 and is fixed through the matching of the linear guide 2 and the tray 3, the hole positions of the orifice plate 4 correspond to the positions of the unit droppers 1102 of the dropper assembly 11 one by one to one, and then all nucleic acid extraction reagents can be dispensed into the orifice plate 4 at a single time, so that the efficiency is improved, a dropper pressing plate 12 is movably connected above the dropper frame 1101, the utility model discloses a reagent bottle, including float board 10, burette cylinder 13, burette clamp plate 12 and burette frame 1101 clearance fit, the both sides of burette clamp plate 12 are connected with burette cylinder 13 through floating joint, one side fixedly connected with electro-magnet 14 that partial shipment machine bottom plate 1 is close to stand optical axis 6, the material of tray 3 is the metal iron, waist type hole has been seted up to electro-magnet 14's both sides, electro-magnet 14 passes through screw and racking machine bottom plate 1 fixed connection, burette clamp plate 12 can reciprocate above burette assembly 11 through the effect of burette cylinder 13, extrude or release all nipple 1104 when burette clamp plate 12 reciprocates, and then realize that all unit burettes 1102 absorb reagent or discharge reagent simultaneously, simple structure and steerable a large amount of unit burette 1102 absorb or discharge reagent.

When in use, firstly, a container with the same size as the pore plate 4 is prepared, the extraction reagent is further loaded into the container, the container is further placed into the tray 3 and pushed to the lower part of the dropper assembly 11 through the linear guide rail 2, the electromagnet 14 is further started to fix the tray 3 through magnetic force, the dropper air cylinder 13 works to push the dropper press plate 12 downwards and press the nipple 1104, the lifting air cylinder 8 works to push the dropper assembly 11 downwards, the unit dropper 1102 contacts the extraction reagent in the container, the dropper air cylinder 13 works to pull the dropper press plate 12 back upwards, the pressed nipple 1104 returns to the original shape and sucks the extraction reagent through the unit dropper 1102, the lifting air cylinder 8 works to pull the dropper assembly 11 back upwards, the electromagnet 14 stops working to push the container to the outer part of the dropper assembly 11 and take the container out of the tray 3, further putting the pore plate 4 filled with the nucleic acid detection reagent tubes into the tray 3, further pushing the tray below the dropper assembly 11 through the linear guide rail 2, further starting the electromagnet 14 to fix the tray 3 through magnetic force, at this time, all the nucleic acid detection reagent tubes are in one-to-one correspondence with the unit droppers 1102, if not, adjusting the position of the electromagnet 14 through the waist-shaped holes at the two sides of the electromagnet 14 to further adjust the fixed position of the tray 3, further operating the lifting cylinder 8 to push the dropper assembly 11 downwards, at this time, inserting the unit droppers 1102 into the nucleic acid sample reagent tubes 5, further operating the dropper cylinder 13 to push the dropper pressing plate 12 downwards and extrude the rubber nipples 1104 to further extrude the extraction reagent in the unit droppers 1102 into the nucleic acid sample reagent tubes 5, the reagent can be dispensed and extracted to all the nucleic acid sample reagent tubes 5 in the pore plate 4 at one time through the simple steps.

To sum up, the continuous dispenser for nucleic acid extraction reagents has the advantages that the continuous dispenser for nucleic acid extraction reagents has the effect of dispensing a large amount of reagents into a large amount of nucleic acid extraction reagents at a time and further improving the efficiency by the matching arrangement of the linear guide rail 2, the tray 3, the pore plate 4 and the dropper assembly 11, the pore plate 4 can slide to the position under the dropper assembly 11 and be fixed by the matching arrangement of the linear guide rail 2 and the tray 3, the hole positions of the pore plate 4 correspond to the positions of the unit droppers 1102 of the dropper assembly 11 one by one, further, all the reagents can be dispensed into the pore plate 4 at a time and further the efficiency is improved, the continuous dispenser for nucleic acid extraction reagents has the effect of completing the suction of a large amount of reagents by a simple control structure and further saving the cost by the matching arrangement of the dropper assembly 11, the dropper pressing plate 12 and the dropper cylinder 13, the dropper pressing plate 12 can move up and down above the dropper assembly 11 by the action of the cylinder 13, when the pipette press plate 12 moves up and down, all the nipples 1104 are squeezed or released, and thus all the unit pipettes 1102 can simultaneously aspirate or discharge the reagent, and the pipette press plate is simple in structure and can control a large number of unit pipettes 1102 to aspirate or discharge the reagent.

The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and equivalent alternatives or modifications according to the technical solution of the present invention and the inventive concept thereof should be covered by the scope of the present invention.

Claims (6)

1. The utility model provides a continuous racking machine of nucleic acid extraction reagent, includes racking machine bottom plate (1), its characterized in that: the upper surface of the subpackaging machine base plate (1) is fixedly connected with a linear guide rail (2), a tray (3) is movably connected above the linear guide rail (2), a pore plate (4) is detachably connected above the tray (3), a nucleic acid sample reagent tube (5) is inserted into the pore plate (4), column optical axes (6) are fixedly connected with the front and the back of the linear guide rail (2), a top plate (7) is fixedly connected above the column optical axes (6), a lifting cylinder (8) is fixedly connected in the middle of the top plate (7), linear bearings (9) are slidably connected on the outer surfaces of the column optical axes (6), floating plates (10) are fixedly connected between the linear bearings (9), a dropper assembly (11) is fixedly connected on the lower surfaces of the floating plates (10), and the dropper assembly (11) comprises a dropper frame (1101), the lower fixedly connected with unit burette (1102) of burette frame (1101), the upper end threaded connection of unit burette (1102) has connecting axle (1103), nipple (1104) have been cup jointed to the top of connecting axle (1103), the top swing joint of burette frame (1101) has burette clamp plate (12), the both sides fixedly connected with burette cylinder (13) of float board (10), one side fixedly connected with electro-magnet (14) that partial shipment machine bottom plate (1) is close to stand optical axis (6).

2. The nucleic acid extraction reagent continuous racking machine according to claim 1, wherein: the burette pressure plate (12) is in clearance fit with the burette frame (1101), and two sides of the burette pressure plate (12) are connected with the burette cylinder (13) through floating joints.

3. The nucleic acid extraction reagent continuous racking machine according to claim 1, wherein: the square groove is formed in the upper portion of the tray (3), the chamfer is formed in the upper portion of the square groove, the square groove is in clearance fit with the pore plate (4), and the depth of the square groove is smaller than the height of the pore plate (4).

4. The nucleic acid extraction reagent continuous racking machine according to claim 1, wherein: the number of the unit burettes (1102) is the same as that of the nucleic acid sample reagent tubes (5), the unit burettes are in one-to-one correspondence with the nucleic acid sample reagent tubes, and a space is arranged between the unit burettes (1102) and the nucleic acid sample reagent tubes (5).

5. The nucleic acid extraction reagent continuous racking machine according to claim 1, wherein: the tray (3) is made of metal iron, waist-shaped holes are formed in two sides of the electromagnet (14), and the electromagnet (14) is fixedly connected with the bottom plate (1) of the subpackaging machine through screws.

6. The nucleic acid extraction reagent continuous racking machine according to claim 1, wherein: the connection part of the connecting shaft (1103) and the unit dropper (1102) is sealed, the connection part of the nipple (1104) and the connecting shaft (1103) is sealed, and air holes are formed in the periphery of the dropper frame (1101).

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