CN216013162U - Colloidal gold immunity detection device based on CCD area array detection - Google Patents
Colloidal gold immunity detection device based on CCD area array detection Download PDFInfo
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- CN216013162U CN216013162U CN202122063330.3U CN202122063330U CN216013162U CN 216013162 U CN216013162 U CN 216013162U CN 202122063330 U CN202122063330 U CN 202122063330U CN 216013162 U CN216013162 U CN 216013162U
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Abstract
The utility model discloses a colloidal gold immunity detection device based on CCD area array detection, which comprises: a body, comprising: a clamping groove is arranged below the main body, a radio frequency card fixing frame is arranged above one side of the clamping groove, a lighting plate fixing frame is arranged above the other side of the clamping groove, and a CCD fixing frame is arranged above the lighting plate fixing frame; a radio frequency card module is fastened on the radio frequency card fixing frame; a lighting board is fastened on the lighting board fixing frame; a CCD detector is fastened on the CCD fixing frame; a multichannel colloidal gold reagent card sets up in the draw-in groove, and it includes: a bottom plate, on which a radio frequency label and a plurality of colloidal gold reagent strips are arranged; an upper cover correspondingly arranged above the bottom plate and provided with a window and a drip hole.
Description
Technical Field
The utility model relates to the field of biological detection equipment, in particular to a colloidal gold immunodetection device based on CCD area array detection.
Background
The colloidal gold immunodetection technology is characterized in that colloidal gold particles are used as markers for detection, wherein the colloidal gold particles are combined with biomolecules through electrostatic adsorption force, a target detected object is combined with biological particles at a detection zone in an immunoreaction mode, the colloidal gold particles combined with the target detected object are gathered to form a pink strip, and then the pink strip is collected to realize automatic reading of a colloidal gold detection result. However, in the prior art, the detection reagent card is a single card, namely, only one biomolecule (pathogenic bacteria, viruses and the like) can be detected in each detection; if a plurality of different biomolecules are to be detected, a plurality of different types of detection reagent cards (all single cards) are required to be used for multiple detections, so that the whole detection process is complex to operate and consumes a long time. With the development of technology, the existing devices for detecting various biomolecules cannot meet the requirement of efficient detection, and therefore, a device capable of providing a simpler and faster detection method is required.
SUMMERY OF THE UTILITY MODEL
In order to solve the problems, the utility model provides a colloidal gold immunoassay device based on CCD area array detection, which can be used for simultaneously detecting various different important pathogenic bacteria, viruses and the like conveniently and efficiently by using a multi-channel colloidal gold reagent card as a detection carrier.
In addition, another purpose of the colloidal gold immunodetection device is to provide a carrier for a detection result by integrating a radio frequency device (a radio frequency tag and a radio frequency card device), so that subsequent recording and extraction of the result are facilitated.
In order to achieve the above object, the present invention provides a colloidal gold immunoassay device based on CCD area array detection, comprising:
a body, the body comprising: the clamping groove is arranged below the main body; the radio frequency card fixing frame is arranged above one side of the clamping groove; the lighting plate fixing frame is arranged above the other side of the clamping groove; the CCD fixing frame is arranged above the lighting plate fixing frame;
the radio frequency card module is fixedly arranged on the radio frequency card fixing frame;
the lighting plate is fixedly arranged on the lighting plate fixing frame;
the CCD detector is fixedly arranged on the CCD fixing frame; and
the multichannel colloidal gold reagent card is arranged in the card slot;
wherein, the multichannel colloidal gold reagent card includes:
a bottom plate, wherein a radio frequency label is arranged on one side of the bottom plate corresponding to the radio frequency card module, and a plurality of colloidal gold reagent strips are arranged on one side of the bottom plate corresponding to the CCD detector;
the upper cover is correspondingly arranged above the bottom plate and is provided with a window, the window is positioned above the plurality of colloidal gold reagent strips, and the upper cover is also provided with a dripping hole which is positioned between the window and the radio frequency tag.
In an embodiment of the present invention, the plurality of gold reagent strips are gold reagent strips for detecting different pathogenic bacteria or viruses.
In an embodiment of the present invention, the number of the plurality of colloidal gold reagent strips is 4.
In an embodiment of the present invention, the plurality of colloidal gold reagent strips are packaged in a form designed according to the test width and the detection distance of the CCD detector.
In an embodiment of the present invention, the radio frequency tag is specifically an RFID tag, and is configured to write the types, corresponding positions, and unique identity codes of the plurality of colloidal gold reagent strips.
In an embodiment of the present invention, a connection manner of the bottom plate and the upper cover is a crimping seal.
In an embodiment of the utility model, wherein the lighting panel comprises a plurality of LED light sources.
In an embodiment of the present invention, the CCD detector is an area array CCD detector, which includes a lens and a CCD chip.
In an embodiment of the present invention, the CCD detector is a color CCD detector or a black and white CCD detector.
In an embodiment of the present invention, a plurality of fixing points are further disposed on the main body.
Compared with the existing single card detection device, the colloidal gold immunodetection device based on CCD area array detection has the advantages that:
1) the multi-channel colloidal gold reagent card is used as a detection carrier, so that various pathogenic bacteria or viruses can be conveniently and rapidly detected at the same time, and the detection efficiency is improved;
2) the information of the reagent strips in the multi-channel colloidal gold reagent card is written in through the integrated radio frequency tag and is read through the radio frequency card module, so that the information such as a detection result can be conveniently recorded.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the drawings without creative efforts.
FIG. 1 is a diagram of a detecting device according to an embodiment of the present invention;
FIG. 2 is a diagram of a multi-channel gold reagent card in a testing device according to an embodiment of the present invention;
FIG. 3 is a top view of a multi-channel colloidal gold reagent card of the detecting device according to an embodiment of the present invention;
FIG. 4 is a schematic view of the package of a multi-channel colloidal gold reagent card in the detecting device according to an embodiment of the utility model;
fig. 5 is a schematic diagram illustrating an operation principle of the detecting device according to an embodiment of the present invention.
Description of reference numerals: 10-multichannel colloidal gold reagent card; 101-a radio frequency tag; 102-colloidal gold reagent strip; 103-drip hole; 104-a window; 201-card slot; 202-a radio frequency card fixing frame; 203-lighting panel holder; 204-a CCD fixing frame; 205-radio frequency card module; 206-an illumination panel; 207-CCD detector; 208-fixed point.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be obtained by a person skilled in the art without inventive effort based on the embodiments of the present invention, are within the scope of the present invention.
Example one
Fig. 1 is a structural diagram of a detection Device according to an embodiment of the present invention, and as shown in fig. 1, the embodiment provides a colloidal gold immunodetection Device based on CCD (Charge-coupled Device, also called photosensitive Device) area array detection, which includes:
a body, the body comprising: a card slot (201) arranged below the main body and used for inserting a reagent card for detection; the radio frequency card fixing frame (202) is arranged above one side of the clamping groove (201); the lighting plate fixing frame (203) is arranged above the other side of the clamping groove (201); a CCD fixing frame (204) arranged above the lighting plate fixing frame (203);
the radio frequency card module (205) is fixedly arranged on the radio frequency card fixing frame (202);
the lighting plate (206) is fixedly arranged on the lighting plate fixing frame (203);
a CCD detector (207) which is tightly fixed on the CCD fixing frame (204);
the multichannel colloidal gold reagent card (10) is arranged in the card slot (201);
fig. 2 is a bottom plate diagram of a multi-channel colloidal gold reagent card in a testing device according to an embodiment of the utility model, and fig. 3 is a top cover diagram of the multi-channel colloidal gold reagent card in the testing device according to an embodiment of the utility model, as shown in fig. 2 and fig. 3, wherein the multi-channel colloidal gold reagent card (10) includes:
a bottom plate, wherein a radio frequency label (101) is arranged on one side of the bottom plate corresponding to the radio frequency card module (205), and a plurality of colloidal gold reagent strips (102) are arranged on one side of the bottom plate corresponding to the CCD detector (207);
the upper cover is correspondingly arranged above the bottom plate, wherein a window (104) is arranged on the upper cover, the window (104) is positioned above the plurality of colloidal gold reagent strips (102) so as to facilitate the CCD detector to detect the colloidal gold reagent strips, a dripping hole (103) is further arranged on the upper cover, and the dripping hole (103) is positioned between the window (104) and the radio frequency tag (101).
In the embodiment, the plurality of colloidal gold reagent strips (102) are colloidal gold reagent strips for detecting different pathogenic bacteria or viruses respectively.
In the embodiment, the number of the plurality of colloidal gold reagent strips (102) is 4. In this embodiment, taking 4 gold reagent strips for detecting different pathogenic bacteria or viruses as an example, which is equivalent to 4 detection channels, 4 different biomolecules can be detected simultaneously, and in other embodiments, the number of the gold reagent strips can be set according to the requirement.
In the embodiment, the packaging form of the plurality of colloidal gold reagent strips (102) is designed according to the testing width and the detection distance of the CCD detector (207) so as to ensure that the plurality of colloidal gold reagent strips can be completely detected by the CCD detector through the window.
Fig. 4 is a schematic diagram illustrating the packaging of a multi-channel colloidal gold reagent card in a detection apparatus according to an embodiment of the present invention, as shown in fig. 4, after a bottom plate and an upper cover of the multi-channel colloidal gold reagent card (10) are packaged, a radio frequency tag (101) is located on one side of the multi-channel colloidal gold reagent card (10), a plurality of colloidal gold reagent strips (102) are located on the other side of the multi-channel colloidal gold reagent card (10), a window (104) is located above the plurality of colloidal gold reagent strips (102), and a drip hole (103) is located between the window (104) and the radio frequency tag (101). When putting into above-mentioned colloidal gold immunity detection device with multichannel colloidal gold reagent card (10), radio frequency label (101) correspond with radio frequency card module (205) to make radio frequency card module (205) can sense radio frequency label (101), window (104) correspond with CCD detector (207), so that CCD detector (207) can detect many colloidal gold reagent strips (102) through window (104), in order to realize the detection to many colloidal gold reagent strips.
In this embodiment, the radio Frequency tag (101) is specifically an rfid (radio Frequency identification) tag, and is used for writing the types, corresponding positions, and unique identification numbers of the plurality of colloidal gold reagent strips (102). The RFID tag and the radio frequency card module used in this embodiment may be of any type, and the writing and reading of the RFID tag may be performed in any manner, which is not limited in the present invention.
In this embodiment, the connection manner between the bottom plate and the upper cover is a crimping seal.
In this embodiment, among other things, the lighting panel (206) comprises a plurality of LED light sources.
In the embodiment, the CCD detector (207) is an area array CCD detector which comprises a lens and a CCD chip.
In the embodiment, the CCD detector (207) is a color CCD detector or a black and white CCD detector. The CCD detector in the embodiment can be any product capable of realizing the CCD detection function, and the utility model aims to improve the whole structure of the device and does not limit the type and the detection mode of the CCD detector.
In the embodiment, a plurality of fixing points (208) are further arranged on the main body and used for fixing the whole device.
Example two
Fig. 5 is a schematic diagram of the working principle of the detection device according to an embodiment of the present invention, and as shown in fig. 1 to 5, the working principle and the using process of the colloidal gold immunoassay device based on CCD area array detection according to the present invention are described as follows:
firstly, packaging a plurality of colloidal gold reagent strips (102) and radio frequency tags (101) for detecting different pathogenic bacteria or viruses on a specified position of a bottom plate according to requirements, and forming a multi-channel colloidal gold reagent card (10) to be tested after an upper cover and the bottom plate are pressed and sealed;
then, fastening a radio frequency card module (205) on a radio frequency card fixing frame (202), fastening an illuminating plate (206) on an illuminating plate fixing frame (203), and fastening a CCD detector (207) on a CCD fixing frame (204);
placing a multi-channel colloidal gold reagent card (10) to be tested into a card slot, placing a radio frequency tag (101) of the multi-channel colloidal gold reagent card corresponding to a radio frequency card module (205) and placing a window (104) of the multi-channel colloidal gold reagent card corresponding to a CCD detector (207), and reading information written in by the radio frequency tag through the radio frequency card module so as to record or extract a detection result, wherein the radio frequency card module and the radio frequency tag can adopt the existing radio frequency identification technology, and are not described in detail in the embodiment;
finally, detection can be performed in a similar manner as detection using a single card. The liquid to be detected is dripped into the liquid dripping hole (103), the light source on the lighting plate (206) irradiates the plurality of colloidal gold reagent strips (102), and the reflected light of the plurality of colloidal gold reagent strips (102) is detected through the CCD detector (207), so that different pathogenic bacteria or viruses are detected simultaneously.
Compared with the single card device in the prior art, the colloidal gold immunodetection device based on CCD area array detection of the utility model takes the multi-channel colloidal gold reagent card as a detection carrier, can conveniently and rapidly detect various pathogenic bacteria or viruses simultaneously, and improves the detection efficiency; the information of the reagent strips in the multi-channel colloidal gold reagent card is written in through the integrated radio frequency tag and is read through the radio frequency card module, and the information such as detection results can be conveniently recorded.
Those of ordinary skill in the art will understand that: the figures are merely schematic representations of one embodiment, and the blocks or flow diagrams in the figures are not necessarily required to practice the present invention.
Those of ordinary skill in the art will understand that: modules in the devices in the embodiments may be distributed in the devices in the embodiments according to the description of the embodiments, or may be located in one or more devices different from the embodiments with corresponding changes. The modules of the above embodiments may be combined into one module, or further split into multiple sub-modules.
Finally, it should be noted that: the above examples are only intended to illustrate the technical solution of the present invention, but not to limit it; although the present invention has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some technical features may be equivalently replaced; and such modifications or substitutions do not depart from the spirit and scope of the corresponding technical solutions of the embodiments of the present invention.
Claims (9)
1. The utility model provides a colloidal gold immunity detection device based on CCD area array is surveyed which characterized in that includes:
a body, the body comprising: the clamping groove is arranged below the main body; the radio frequency card fixing frame is arranged above one side of the clamping groove; the lighting plate fixing frame is arranged above the other side of the clamping groove; the CCD fixing frame is arranged above the lighting plate fixing frame;
the radio frequency card module is fixedly arranged on the radio frequency card fixing frame;
the lighting plate is fixedly arranged on the lighting plate fixing frame;
the CCD detector is fixedly arranged on the CCD fixing frame; and
the multichannel colloidal gold reagent card is arranged in the card slot;
wherein, the multichannel colloidal gold reagent card includes:
a bottom plate, wherein a radio frequency label is arranged on one side of the bottom plate corresponding to the radio frequency card module, and a plurality of colloidal gold reagent strips are arranged on one side of the bottom plate corresponding to the CCD detector;
the upper cover is correspondingly arranged above the bottom plate and is provided with a window, the window is positioned above the plurality of colloidal gold reagent strips, and the upper cover is also provided with a dripping hole which is positioned between the window and the radio frequency tag.
2. The gold immunoassay device of claim 1, wherein the plurality of gold reagent strips are gold reagent strips for detecting different pathogenic bacteria or viruses.
3. The gold immunoassay device of claim 2, wherein the plurality of gold reagent strips is 4 strips.
4. A colloidal gold immunoassay device according to claim 1, wherein the radio frequency tag is specifically an RFID tag for writing the kind, corresponding position, and unique identification code of the plurality of colloidal gold reagent strips.
5. The gold immunoassay device of claim 1, wherein the bottom plate and the top cover are connected by a crimping seal.
6. The gold immunoassay device of claim 1, wherein the illumination plate comprises a plurality of LED light sources.
7. The gold immunoassay device of claim 1, wherein the CCD detector is an area array CCD detector comprising a lens and a CCD chip.
8. The gold immunoassay device of claim 7, wherein the CCD detector is a color CCD detector or a black and white CCD detector.
9. The gold immunoassay device of claim 1, wherein the body further comprises a plurality of fixing points.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202122063330.3U CN216013162U (en) | 2021-08-30 | 2021-08-30 | Colloidal gold immunity detection device based on CCD area array detection |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202122063330.3U CN216013162U (en) | 2021-08-30 | 2021-08-30 | Colloidal gold immunity detection device based on CCD area array detection |
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| Publication Number | Publication Date |
|---|---|
| CN216013162U true CN216013162U (en) | 2022-03-11 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202122063330.3U Active CN216013162U (en) | 2021-08-30 | 2021-08-30 | Colloidal gold immunity detection device based on CCD area array detection |
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| CN (1) | CN216013162U (en) |
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2021
- 2021-08-30 CN CN202122063330.3U patent/CN216013162U/en active Active
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