CN215866705U - Biochemical analyzer - Google Patents

Abstract

The application discloses a biochemical analyzer. The biochemical analyzer includes: the centrifugal machine comprises a frame assembly and a centrifugal assembly, wherein a guide rail is arranged on the frame assembly; the centrifugal assembly is arranged on the frame assembly and used for bearing the reagent disk and driving the reagent disk to rotate so as to enable the reagent disk to do centrifugal motion, and a sliding block is arranged on the centrifugal assembly and arranged with the guide rail in a sliding mode. The utility model provides a centrifugal component adopts the mode of guide rail transmission, can strengthen the stability of reagent dish business turn over storehouse process, and centrifugal component's transmission structure has longer life.

Description

Biochemical analyzer

Technical Field

The application relates to the technical field of biochemical analysis equipment, in particular to a biochemical analyzer.

Background

The biochemical analyzer comprises a centrifugal component, the centrifugal component is used for bearing a reagent tray, and the centrifugal component enters and exits the bin through a transmission mechanism.

In the prior art, a transmission mechanism of a centrifugal assembly usually uses a split module, namely, two straight rods are inserted for sliding transmission, the transmission structure is easy to loosen, and after multiple times of entering and exiting, the transmission mechanism may deform and is not high in stability.

SUMMERY OF THE UTILITY MODEL

The application provides a biochemical analyzer to solve among the prior art biochemical analyzer transmission structure of centrifugal component easily not hard up, the not high problem of stability.

In order to solve the above technical problem, the present application provides a biochemical analyzer, including: the frame assembly is provided with a guide rail; the centrifugal assembly is arranged on the frame assembly and used for bearing the reagent disk and driving the reagent disk to rotate so as to enable the reagent disk to do centrifugal motion, and a sliding block is arranged on the centrifugal assembly and arranged with the guide rail in a sliding mode.

Furthermore, the biochemical analyzer also comprises a driving part, and the driving part is connected with the sliding block and is used for driving the sliding block to slide along the guide rail.

Further, the driving part comprises a gear, a rack is arranged on the sliding block, and the gear is meshed with the rack so that the driving part drives the sliding block to move.

Further, the guide rail includes first guide rail and second guide rail, and first guide rail and second guide rail are parallel and the interval sets up on frame set spare, and the slider includes first slider and second slider, and first slider sets up with first guide rail is slided, and the second slider sets up with the second guide rail is slided.

Furthermore, the frame subassembly includes support and fixing base, and the fixing base bears on the support, and the fixing base is formed with the test chamber for the holding centrifugation subassembly.

Furthermore, a first opening is formed in the side wall of the test cavity, the extending direction of the guide rail is perpendicular to the plane where the first opening is located, and the centrifugal assembly enters and exits the test cavity through the first opening.

Further, a cover plate is arranged on one side, away from the test cavity, of the centrifugal assembly and used for blocking the first opening.

Further, be provided with the second opening on the diapire of test chamber, centrifugal component includes first driving piece, and first driving piece is used for driving reagent dish and rotates, and first driving piece is inserted and is placed in the second opening.

Furthermore, the biochemical analyzer also comprises a limiting plate, and the limiting plate is positioned on one side of the guide rail.

Furthermore, the centrifugal assembly is provided with a clamping fastener for clamping on the frame assembly so as to prevent the centrifugal assembly from falling off from the frame assembly.

The beneficial effect of this application does: different from the prior art, the biochemical analyzer comprises a frame assembly and a centrifugal assembly positioned on the frame assembly, wherein the frame assembly is provided with a guide rail; the centrifugal assembly is provided with a sliding block, and the sliding block and the guide rail are arranged in a sliding mode. The transmission structure of this application centrifugation subassembly adopts the mode of guide rail, can strengthen the stability of reagent dish business turn over storehouse process, and this transmission structure reliability is high, can improve biochemical analyzer's life.

Drawings

In order to more clearly illustrate the technical solutions in the embodiments of the present application, the drawings needed to be used in the description of the embodiments are briefly introduced below, and it is obvious that the drawings in the following description are only some embodiments of the present application, and it is obvious for those skilled in the art to obtain other drawings based on these drawings without creative efforts.

FIG. 1 is a schematic structural view of one embodiment of a biochemical analyzer provided herein;

FIG. 2 is an exploded view of the biochemical analyzer of FIG. 1;

FIG. 3 is a schematic view showing the structure of a reagent disk holding unit in the biochemical analyzer of FIG. 1;

FIG. 4 is a schematic view showing the structure of a reagent disk holding base in the reagent disk holding apparatus shown in FIG. 3;

FIG. 5 is a schematic structural view of one embodiment of the reagent disk of FIG. 2;

FIG. 6 is a schematic side view of the reagent disk securing apparatus of FIG. 3;

FIG. 7 is a schematic view of the biochemical analyzer of FIG. 1 with a cover removed;

FIG. 8 is a schematic side view of the biochemical analyzer of FIG. 7;

FIG. 9 is a schematic view showing the construction of a centrifuge assembly and a driving part in the biochemical analyzer shown in FIG. 7;

FIG. 10 is a schematic view of the frame assembly of the biochemical analyzer of FIG. 1;

FIG. 11 is a schematic view showing the construction of a detecting unit in the biochemical analyzer shown in FIG. 1;

FIG. 12 is a schematic structural view of a rear light splitting assembly in the detecting device shown in FIG. 11;

FIG. 13 is a schematic view of the structure of a light splitter and a photodiode in the detecting device shown in FIG. 12;

FIG. 14 is a schematic view of the biochemical analyzer shown in FIG. 1, in which the centrifugal module is located at a centrifugal position;

FIG. 15 is a schematic view of the construction of the centrifugal module in the biochemical analyzer shown in FIG. 1 at the detection site;

FIG. 16 is a schematic view of another perspective of the biochemical analyzer shown in FIG. 1;

FIG. 17 is a schematic flow chart diagram of one embodiment of a detection method for a biochemical analyzer provided herein;

FIG. 18 is a schematic view of the reagent disk of FIG. 2 from another perspective;

FIG. 19 is a schematic flow diagram of one embodiment of a centrifugation method for a biochemical analyzer provided herein;

FIG. 20 is a schematic flow chart of another embodiment of a centrifugation method of a biochemical analyzer provided herein.

Detailed Description

The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application, and it is obvious that the described embodiments are only a part of the embodiments of the present application, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present application.

It should be noted that if directional indications (such as up, down, left, right, front, and back … …) are referred to in the embodiments of the present application, the directional indications are only used to explain the relative positional relationship between the components, the movement situation, and the like in a specific posture (as shown in the drawings), and if the specific posture is changed, the directional indications are changed accordingly.

In addition, if there is a description of "first", "second", etc. in the embodiments of the present application, the description of "first", "second", etc. is for descriptive purposes only and is not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. In addition, technical solutions between various embodiments may be combined with each other, but must be realized by a person skilled in the art, and when the technical solutions are contradictory or cannot be realized, such a combination should not be considered to exist, and is not within the protection scope of the present application.

Biochemical analyzers, also commonly referred to as biochemics, are instruments that use the principle of photoelectric colorimetry to measure a particular chemical component in a sample to be tested. Because of its fast measuring speed, high accuracy and small reagent consumption, it is widely used in hospitals of all levels, epidemic prevention stations, pet hospitals, etc.

The application provides a biochemical analyzer, this biochemical analyzer simple structure, the volume is less, and the cost is lower, and can detect the sample that waits to detect in the reagent dish fast accurately, therefore has stronger practicality. The sample to be tested may comprise blood, saliva or sweat, etc., without limitation.

The biochemical analyzer of the present application will be described below by taking a biochemical analyzer for blood detection as an example.

Referring to fig. 1 and fig. 2, fig. 1 is a schematic structural diagram of a biochemical analyzer provided in the present application, and fig. 2 is an exploded view of the biochemical analyzer 100 in fig. 1, specifically, the biochemical analyzer 100 includes: a frame assembly 11, a reagent tray fixing device 12, a light source assembly 13, a rear light splitting assembly 14 and a temperature adjusting assembly 16. The fixing device 12 of the reagent tray, the light source assembly 13, the rear light splitting assembly 14 and the temperature adjusting assembly 16 are all arranged on the frame assembly 11. The structure of each part of the biochemical analyzer 100 will be described in detail below.

The reagent disk holding means 12 is for holding the reagent disk 2. When the biochemical analyzer 100 needs to detect a sample to be detected, the reagent tray 2 provided with the sample to be detected is placed on the fixing device 12 of the reagent tray. In a high-speed biochemical analyzer, the reagent disk 2 is generally in a disk type structure, a reagent required for a test is stored in the reagent disk 2, and a sample to be detected is placed in the reagent disk 2 so as to be detected in the reagent disk 2 by the biochemical analyzer 100. The present application is not particularly limited with respect to the specific structure of the reagent disk 2.

Further, referring to fig. 3 to fig. 6, fig. 3 is a schematic structural view of the fixing device 12 of the reagent disk in the biochemical analyzer shown in fig. 1, fig. 4 is a schematic structural view of the reagent disk fixing seat in the reagent disk fixing device 12 shown in fig. 3, and fig. 5 is a schematic structural view of an embodiment of the reagent disk 2 shown in fig. 2; figure 6 is a schematic side view of the reagent disk holding device 12 of figure 3. The reagent disk holding device 12 comprises a reagent disk holder 121 and a magnetic connector 122.

The magnetic connector 122 is disposed on the reagent disk fixing seat 121 and is configured to be magnetically connected to the reagent disk 2. Specifically, the reagent disk 2 includes a disk body 28 and a connecting member 29, and the connecting member 29 is provided on the disk body 28. When the reagent disk 2 is positioned on the reagent disk holding means 12, the attachment 29 on the reagent disk 2 is magnetically connected to the magnetic attachment 122 on the reagent disk holding means 12.

In this embodiment, the magnetic connector 122 is a permanent magnet or an electromagnet. The permanent magnet refers to a magnet capable of maintaining its magnetism for a long period of time, such as a magnet and artificial magnetic steel. An electromagnet refers to a device that is composed of a core and a coil and that generates a magnetic field when a current flows through the coil. The connection 29 on the reagent disk 2 may be a metal or metal alloy, in such a way that the magnetic connection 122 can be magnetically connected with the metal or metal alloy on the reagent disk 2. Of course, the connecting member 29 of the reagent disk 2 may be a permanent magnet or an electromagnet, and the reagent disk 2 may be magnetically attracted to the reagent disk holder 121 by the principle of opposite attraction.

In other embodiments, the magnetic connecting member 122 may also be a metal or metal alloy member, the connecting member 29 on the reagent disk 2 is a magnet, such as a permanent magnet or an electromagnet, and the metal or metal alloy member on the reagent disk holder 121 is used to magnetically connect with the magnet on the reagent disk 2. In particular, the magnetic coupling 122 may include an alloy of iron, nickel, cobalt, or at least two of the foregoing. For example, the magnetic connecting member 122 may be an iron sheet or a nickel sheet, and the reagent disk 2 is provided with a magnet capable of generating a magnetic field, and the magnet attracts a metal such as the iron sheet or the nickel sheet, so as to fix the reagent disk 2 on the reagent disk fixing seat 121.

In the above embodiment, the reagent tray 2 is magnetically connected to the reagent tray fixing seat 121, the reagent tray 2 is conveniently mounted and taken out, the mounting efficiency of the reagent tray 2 can be improved, and the cost of the magnetic connecting piece 122 is low, so that the production and manufacturing cost of the biochemical analyzer 100 can be saved.

Further, as shown in fig. 4, a first groove 123 is formed on the reagent disk fixing seat 121, and the magnetic connecting member 122 is located in the first groove 123. As shown in fig. 5, a first step 281 is disposed on the tray 28, a receiving cavity (not shown) is formed in the first step 281, and the connecting member 29 is disposed in the receiving cavity. The first groove 123 corresponds to the first step 281 on the reagent disk 2, and when the reagent disk 2 is fixed, the first step 281 is embedded in the first groove 123, so that the connecting piece 29 in the first step 281 is magnetically connected with the magnetic connecting piece 122 in the first groove 123, thereby being beneficial to fixing the reagent disk 2 and reducing the volume of the fixing device 12 of the reagent disk.

Further, as shown in fig. 4, a second groove 124 is disposed on the reagent disk fixing seat 121, and a first groove 123 is disposed on a bottom wall of the second groove 124, that is, the first groove 123 and the second groove 124 are distributed in a step shape to match with the shape of the reagent disk 2, so as to facilitate fixing of the reagent disk 2. The magnetic connecting piece 122 is arranged in the first groove 123, the cross section of the second groove 124 along the first plane is polygonal, wherein the first plane is parallel to the bottom wall of the second groove 124, that is, the inner side wall of the second groove 124 comprises a plurality of planes which are connected in sequence, and the second groove 124 forms a polygonal recess. Optionally, the area of the opening of the first groove 123 may be larger than the area of the bottom wall of the first groove 123, and the arrangement manner of the upper portion being wide and the lower portion being narrow enables the reagent disk 2 to be more closely attached to the polygonal recess in the process of being placed, so as to improve the reliability of fixing the reagent disk 2.

As shown in fig. 5, a second step 283 is further disposed on the tray body 28, the second step 283 is disposed on the periphery of the first step 281, and the second step 283 is a polygonal step. The polygon recess on reagent dish fixing base 121 cooperates with the polygon step on the reagent dish 2 to carry on spacingly to reagent dish 2. When the fixing base 111 rotates, due to the limiting effect of the second groove 124, the reagent tray 2 can be better embedded in the reagent tray fixing base 121, the reagent tray 2 is prevented from slipping in the reagent tray fixing base 121, and the detection reliability of the biochemical analyzer 100 is improved. The polygon herein refers to a closed geometric figure formed by three or more sides, for example, the polygon may be a triangle, a quadrangle, a pentagon, a hexagon, a heptagon, etc.

In this embodiment, a boss (not shown) is disposed on the bottom wall of the first groove 123, the magnetic connecting member 122 is fixed on the boss, and the magnetic connecting member 122 can be fixed on the boss by a fastener such as a screw. In other embodiments, the boss may be directly fixed to the bottom wall of the first recess 123 to simplify the structure of the reagent disk fixing device 12.

Optionally, as shown in fig. 4, a tool withdrawal groove 126 is provided at a junction of two adjacent surfaces in the inner side wall of the second groove 124, so as to facilitate tool withdrawal when the reagent disk fixing seat 121 is machined, and to facilitate abutment with an adjacent part when the reagent disk fixing seat is assembled.

Further, a plurality of positioning pillars 125 are disposed on the bottom wall of the second groove 124, and the plurality of positioning pillars 125 are disposed around the opening of the first groove 123. In this embodiment, the bottom wall of the second groove 124 is provided with 4 positioning pillars 125, wherein four positioning pillars 125 are disposed around the opening of the first groove 123 at equal intervals. The second step 283 of the reagent disk 2 is provided with a positioning hole 284, and the positioning column 125 is embedded in the positioning hole 284 to position the reagent disk 2. In other embodiments, the number of the positioning pillars 125 may also be 3 or 5, and the like, and is not limited herein.

It is noted that reference to "a plurality" in this document can refer to two or more.

Further, as shown in fig. 6, the reagent disk fixing device 12 further includes a first driving member 127, and the first driving member 127 is connected to the reagent disk fixing seat 121 and drives the reagent disk fixing seat 121 to rotate so as to centrifuge the reagent disk 2. The first driving member 127 drives the reagent tray fixing seat 121 to rotate at a first rotation speed, which may be greater than or equal to 4000 rpm. That is, the first driving member 127 can drive the reagent disk 2 to rotate at a high speed, and the first driving member 127 can be a dc motor.

In the above embodiment, the reagent disk holding unit 12 holds the reagent disk 2 and drives the reagent disk 2 to rotate at a high speed, so as to centrifuge the reagent disk 2. The reagent disk holding device 12 described above may be used in this application as a centrifuge assembly 12 (hereinafter centrifuge assembly 12) where the centrifuge assembly 12 comprises a reagent disk holder 121, a magnetic coupling 122 and a first drive member 127, and the centrifuge assembly 12 is arranged to drive the reagent disk 2 in rotation to centrifuge the reagent disk 2.

It is noted that, as will be appreciated by those skilled in the art, reference herein to a centrifuge assembly 12 shall include the various forms of reagent disk holding arrangements 12 described above and shall not be limited to a particular embodiment.

Further, as shown in fig. 7 and 8, fig. 7 is a schematic structural view of the biochemical analyzer shown in fig. 1 with a cover plate removed, fig. 8 is a schematic structural view of a side view of the biochemical analyzer shown in fig. 7, and the centrifugal module 12 is located on the frame module 11.

The frame component 11 can be provided with a guide rail 110, the centrifugal component 12 can be provided with a slide block 120, the slide block 120 and the guide rail 110 are arranged in a sliding manner, and the slide block 120 slides in the guide rail 110 to drive the centrifugal component 12 to move on the frame component 11, and the moving process is smooth, so that the transmission process of the centrifugal component 12 is stable and reliable. The biochemical analyzer 100 of the present embodiment is simple in structure and facilitates the sliding of the centrifugation section 12 into and out of the frame section 11.

Further, as shown in fig. 9, fig. 9 is a schematic structural diagram of a centrifugal assembly and a driving part in the biochemical analyzer shown in fig. 7, and the biochemical analyzer 100 further includes a driving part 116, and the driving part 116 is connected to the slider 120 for driving the slider 120 to slide along the guide rail 110. Here, the connection of the driving member 116 to the slider 120 includes the direct connection of the output end of the driving member 116 to the slider 120, and the indirect connection of the output end of the driving member 116 to the slider 120 via another member, as long as the slider 120 can be driven to move. In this embodiment, the driving member 116 can drive the centrifugal assembly 12 to slide in the frame assembly 11, so that the biochemical analyzer 100 can be automated to a high degree. The driving member 116 may be a motor or an air cylinder.

Further, as shown in fig. 9, the driving member 116 may include a gear 117, and the slider 120 may be provided with a rack 129, and the gear 117 is engaged with the rack 129, so that the driving member 116 can drive the slider 120 to move. In this way, the distance that the driving member 116 drives the centrifugal assembly 12 to move can be controlled, and thus the reliability of the biochemical analyzer 100 can be improved.

As shown in fig. 8, a limiting plate 101 is disposed on the frame assembly 11, the limiting plate 101 is located on one side of the guide rail 110, and is used for limiting the guide rail 110, the limiting plate 101 can be used for determining the installation position of the guide rail 110, so that a user can install the guide rail 110 conveniently, and thus, the biochemical analyzer 100 is convenient to produce.

As shown in fig. 10, fig. 10 is a schematic structural diagram of the frame assembly 11 in the biochemical analyzer shown in fig. 1, the frame assembly 11 is formed with a test cavity 113, specifically, the frame assembly 11 includes a bracket 112 and a fixing seat 111, the fixing seat 111 is carried on the bracket 112, the centrifugal assembly 12 is disposed on the fixing seat 121, the fixing seat 121 forms the test cavity 113 for accommodating the centrifugal assembly 12, and the test cavity 113 can be used as a reaction chamber of the reagent disk 2.

Further, as shown in fig. 10, a first opening 114 is disposed on a side wall of the test chamber 113, the first opening 114 is communicated with the test chamber 113, the centrifugal assembly 12 enters and exits the test chamber 113 through the first opening 114, and the centrifugal assembly 12 can reach a position out of the bin through the first opening 114, so that a user can place the reagent disk 2 on the centrifugal assembly 12 and then enter the test chamber 113 through the first opening 114, so that the biochemical analyzer 100 can perform corresponding detection on the reagent disk 2. The guide rail 110 extends in a direction perpendicular to the plane of the first opening 114 to facilitate rapid entry and exit of the centrifuge assembly 12 into and out of the test chamber 113 through the first opening 114.

Referring again to fig. 2 and 3, the centrifuge assembly 12 is provided with a cover plate 108 on a side away from the test chamber 113, the cover plate 108 being used to close off the first opening 114. When the centrifuge assembly 12 is located in the test chamber 113, the cover plate 108 blocks the first opening 114 to close the test chamber 113, so that the interference of the external environment to the reagent disk 2 in the test chamber 113 can be reduced.

Furthermore, a second opening 115 is disposed on the bottom wall of the test chamber 113, the second opening 115 is communicated with the first opening 114, the centrifugation component 12 includes a first driving member 127, the first driving member 127 is connected to the reagent disk fixing seat 121 for driving the reagent disk fixing seat 121 to rotate, and the first driving member 127 is inserted into the second opening 115 so that the first driving member 127 is at least partially located outside the test chamber 113. In this way, space in the test chamber 113 can be saved, and the influence of the first driving member 127 on the temperature in the test chamber 113 can be reduced.

Further, the biochemical analyzer 100 may be configured in a dual-guide structure, so that the transportation process of the centrifugal assembly 12 is more stable and the service life of the biochemical analyzer 100 can be prolonged.

Specifically, as shown in fig. 8, the guide rail 110 includes a first guide rail 104 and a second guide rail 105, the first guide rail 104 and the second guide rail 105 are disposed on the frame assembly 11 in parallel and at an interval, the slider 120 includes a first slider 102 and a second slider 103, the first slider 102 is disposed to slide on the first guide rail 104, and the second slider 103 is disposed to slide on the second guide rail 105. Wherein the first guide rail 104 and the second guide rail 105 are respectively located at two opposite ends of the second opening 115 to increase the stability of the biochemical analyzer 100.

Further, the end of the slider 120 is provided with a latch (not labeled), wherein the end of the slider 120 refers to the end of the slider 120 away from the cover 108. The slider 120 moves along with the movement of the engaging member, and the engaging member is engaged with the frame member 11 to prevent the centrifuge unit 12 from falling off the frame member 11, thereby improving the safety of the biochemical analyzer 100. Wherein the fastener can be a screw to save cost of the biochemical analyzer 100.

The centrifugal assembly 12 is slidably connected to the frame assembly 11 through the guide rail 110 and the slider 120, so that the moving process of the centrifugal assembly 12 is smoother and more stable, and the service life of the biochemical analyzer 100 can be prolonged.

In the above embodiment, the biochemical analyzer 100 carries the reagent disk 2 by the centrifugal component 12, and drives the reagent disk 2 to perform a centrifugal motion, so that the sample to be detected in the reagent disk 2 enters the reagent hole containing the reagent. For a specific method of the centrifugation component 12 for driving the reagent disk 2 to perform the centrifugation motion, refer to the following description of the embodiment.

As shown in fig. 1 and 2, the biochemical analyzer 100 includes a detecting device for detecting the reagent disk 2 to obtain an analysis result of a sample to be detected. Specifically, the detection device includes the above-mentioned frame assembly 11, and a light source assembly 13, a rear light splitting assembly 14 and a temperature adjusting assembly 16 which are located on the frame assembly 11.

Specifically, the light source assembly 13 is configured to emit a light beam, and the light beam emitted by the light source assembly 13 passes through the detection position of the reagent disk 2. As shown in fig. 11, the light source assembly 13 includes a light source 131 and a lens assembly 133, and the light source 131 emits a light beam which passes through the detection position of the reagent disk 2 after being collected by the lens assembly 133. In this application, the detection position of the reagent disk 2 refers to a reagent well in which a reagent is stored, that is, a reagent well through which a light beam passes through the reagent disk 2 after being collected by the lens unit 133.

In this embodiment, the light source 131 is a halogen lamp. In the prior art, a light source is generally a xenon flash lamp, and the price of the xenon flash lamp is high, so that the cost of a biochemical analyzer is high. In the present application, the light source 131 is a halogen lamp, which has a low cost and can reduce the production cost of the biochemical analyzer 100. In addition, the light beam emitted by the halogen lamp has a wide wavelength range, a small volume and high luminous efficiency, so that the halogen lamp can be well applied to the biochemical analyzer 100 for detecting the reagent disk 2.

As shown in fig. 7, a heat dissipation assembly 132 is further disposed on one side of the light source assembly 13 for dissipating heat generated by the light source assembly 13. The heat generated from the halogen lamp is dissipated through the heat dissipation assembly 132 installed beside the light source assembly 13. Specifically, the heat dissipating assembly 132 includes a heat sink 1321 and a fan 1322, heat can be more easily dissipated by the special structure of the heat sink 1321, and the fan 1322 is disposed at one side of the heat sink 1321 to accelerate air flow, thereby increasing the heat dissipating effect of the heat sink 1321. Optionally, the heat dissipation fins 1321 are designed with a double-sided heat dissipation manifold to further accelerate heat dissipation and increase heat dissipation.

In other embodiments, the light source 131 may also be a Light Emitting Diode (LED) lamp. Preferably, the light source 131 may be a white LED, which can satisfy the measurement requirements of the biochemical analyzer 100 in a certain measurement range.

As shown in fig. 11, the rear light splitting assembly 14 is located at one side of the light source assembly 13, and specifically, the rear light splitting assembly 14 is located at one side of the reagent disk 2 away from the light source assembly 13, and is used for processing the light beam passing through the detection position of the reagent disk 2.

Further, a mirror 141 is provided on the rear spectroscope assembly 14 for adjusting the traveling direction of the light beam passing through the detection position of the reagent disk 2. That is, the optical path is changed by the mirror 141 so that the optical path propagates along a predetermined direction, which may be determined according to the specific structure of the biochemical analyzer.

The placement position and the placement angle of the mirror 141 can be determined by the propagation direction of the light beam. In this embodiment, the angle between the reflective mirror 141 and the horizontal plane is 135 degrees, and the light beam passing through the detection position of the reagent disk 2 propagates in the vertical direction and propagates in the horizontal direction after being reflected by the reflective mirror 141. That is, the mirror 141 adjusts the light beam traveling in the vertical direction to travel in the horizontal direction. Thus, the original vertical structure of the rear light splitting assembly 14 can be changed into the horizontal structure, the overall thickness of the rear light splitting assembly 14 is reduced, and the volume of the biochemical analyzer 100 is reduced.

In other embodiments, the optical path can be changed to other angles depending on the specific configuration of the biochemical analyzer 100. For example, a vertically propagating beam is adjusted to propagate at an angle of 10 degrees to the horizontal.

In the above embodiment, the light beam emitted from the halogen lamp is collected by the lens part 133, then travels vertically downward and passes through the detection position of the reagent disk 2, and is converted into parallel light by the convex lens, and the parallel light is adjusted to a laterally traveling light beam after being reflected by the reflecting mirror 141. The biochemical analyzer 100 of the present application adopts a post-light splitting manner, simplifies the overall structure thereof, reduces the overall height of the biochemical analyzer 100, and optimizes the structural layout inside the biochemical analyzer 100.

As shown in fig. 12 and 13, the rear light splitting assembly 14 further includes a plurality of light splitting sheets 142 and a plurality of optical filters (not shown), the plurality of light splitting sheets 142 are disposed on one side of the reflective mirror 141 and are arranged in a horizontal direction, an included angle between the plurality of light splitting sheets 142 and the horizontal direction is 45 degrees or 135 degrees, the light splitting sheets 142 are used for splitting the light beam passing through the reagent disk 2 to separate light with different wavelengths, the plurality of optical filters are respectively disposed corresponding to the plurality of light splitting sheets 142 and are used for further filtering the light split by the plurality of light splitting sheets 142, and the optical filters are used for passing only light with specific color and wavelength and absorbing the others. The light passing through the filter is finally absorbed by the photodiode 143 for detection analysis.

In order to reduce the overall length of the rear spectroscope assembly 14, the light split by the adjacent spectroscopes 142 may be propagated in opposite directions, and thus, the plurality of photodiodes 143 may be arranged on both sides of the plurality of spectroscopes 142.

In this embodiment, ten light-splitting plates 142 with different specifications are disposed in the rear light-splitting assembly 14 to separate light with different wavelengths from the light beam, the transverse light beam is separated into light beams with ten different wavelengths by the ten light-splitting plates 142 with different specifications in the rear light-splitting assembly 14, and the filter with corresponding wavelength allows light with specific wavelength to pass through for analysis of the detection item. The specific specifications of the beam splitter 142 and the filter can be selected according to the wavelength required to be selected, and the beam splitter 142 and the filter belong to the scope understood by those skilled in the art, and are not specifically limited herein.

As shown in fig. 1 and 11, the temperature adjusting assembly 16 is disposed on the frame assembly 11 and is used for controlling the temperature in the frame assembly 11 within a preset range, so that the reagent tray 2 can be at a proper temperature, and the sample to be detected and the reagent in the reagent hole are prevented from deteriorating, thereby improving the accuracy of the detection result.

Further, as shown in fig. 11, the temperature adjusting assembly 16 includes a cooling mechanism 161 and a heating mechanism (not shown), the cooling mechanism 161 is used for lowering the temperature in the frame assembly 11, and the heating mechanism is used for raising the temperature in the frame assembly 11. For example, the temperature adjustment assembly 16 may control the temperature of the frame assembly 11 to be in a range between 20 degrees celsius and 30 degrees celsius, and if the temperature of the frame assembly 11 is lower than 20 degrees celsius, the frame assembly 11 may be heated by the heating mechanism, and if the temperature of the frame assembly 11 is higher than 30 degrees celsius, the frame assembly 11 may be cooled by the cooling mechanism 161.

The biochemical analyzer 100 of the present application not only can reduce the temperature of the reaction chamber of the biochemical analyzer 100, but also can improve the temperature of the reaction chamber of the biochemical analyzer 100, thereby improving the temperature controllability of the biochemical analyzer 100 to the reaction chamber, enabling the biochemical analyzer 100 to be capable of detecting in various environments, and improving the adaptability of the biochemical analyzer 100 to the environment.

Further, as shown in fig. 11, in the present embodiment, the refrigeration mechanism 161 includes a refrigeration sheet (not shown), a heat dissipation plate 1612 and a fan 1611, the heat dissipation plate 1612 is connected to the refrigeration sheet for absorbing heat of the refrigeration sheet, and the fan 1611 is located at one side of the heat dissipation plate 1612 for dissipating heat from the heat dissipation plate 1612. When the ambient temperature is higher, the refrigeration piece is through the mode of generating heat while refrigerating, hugs closely the interior panel beating on the frame subassembly 11 with the refrigeration face of refrigeration piece, absorbs the heat in the frame subassembly 11, and the cooperation that the heating face passes through fin 1612 and fan 1611 is with the heat fast dissipation. In other embodiments, the refrigeration mechanism 161 may have other configurations.

The heating mechanism (not marked in the figure) comprises a heating sheet, a temperature protector and a mounting metal plate. When the ambient temperature is low, the heating fins raise the temperature within the frame assembly 11 by heating the mounting sheet metal around them.

As shown in fig. 11, the detecting device further comprises a second driving member 15, the second driving member 15 is used for driving the reagent disk 2 to rotate at a low speed when the centrifugal assembly 12 is located at the detecting position, so that the light beam emitted by the light source assembly 13 passes through all the detecting positions of the reagent disk 2. The second driving member 15 drives the reagent disk 2 to rotate at a speed not greater than 120 rpm. In this embodiment, the reagent disk 2 is driven by the second driving member 15 at 10 rpm during the detection, and in other embodiments, the reagent disk 2 may be driven by the second driving member 15 at 15 rpm or 20 rpm.

As shown in fig. 9, 14 and 15, the biochemical analyzer 100 of the present application has an centrifugation site and a detection site, and the driving member 116 can drive the centrifugation assembly 12 to move to the centrifugation site or the detection site. As shown in fig. 9 and 14, when the centrifugation assembly 12 is in the centrifugation position, the first driving member 127 drives the reagent disk fixing seat 121 to rotate at a high speed to centrifuge the reagent disk 2. As shown in fig. 9 and 15, when the reagent disk fixing seat 121 is located at the detection position, the second driving member 15 drives the reagent disk fixing seat 121 to rotate at a low speed, so that the light beam can pass through each reagent hole of the reagent disk 2.

Wherein, the centrifugation position means that when the centrifugation assembly 12 is located at the position in the frame assembly 11, the centrifugation assembly 12 drives the reagent disk 2 to rotate at a high speed to centrifuge the reagent disk 2. The detection position refers to that when the reagent disk fixing seat 121 is at the position on the frame assembly 11, the second driving member 15 drives the reagent disk 2 to rotate at a low speed, and the light beam can pass through the detection position of the reagent disk 2 to detect the reagent disk 2.

Specifically, when the centrifugation component 12 is located at the centrifugation position of the biochemical analyzer 100, the first driving component 127 drives the reagent disk fixing seat 121 to rotate at the first rotation speed so as to centrifuge the reagent disk; when the centrifugal assembly 12 is located at the detection position of the biochemical analyzer 100, the second driving member 15 drives the reagent disk fixing seat 121 to rotate at the second rotation speed, so that the biochemical analyzer 100 detects the reagent disk 2.

In this application, the first rotation speed is greater than the second rotation speed, that is, the first driving member 127 drives the reagent disk 2 to rotate at a high speed, and the second driving member 15 drives the reagent disk 2 to rotate at a low speed. As described above, the first rotation speed is not less than 4000 rpm, and the second rotation speed is not greater than 120 rpm, which is not described herein again.

Further, as shown in fig. 9 and fig. 15, a first gear 128 is disposed on the periphery of the reagent disk fixing seat 121, and the second driving member 15 includes a second gear 151, where the second gear 151 is configured to mesh with the first gear 128, so that the second driving member 15 drives the reagent disk fixing seat 121 to rotate.

When the centrifugal assembly 12 is in the centrifugal position, the second gear 151 is not engaged with the first gear 128, so that the first driving member 127 can drive the reagent disk fixing seat 121 to rotate.

After reagent dish fixing base 121 moved to detecting the position, second gear 151 and first gear 128 meshing to make second driving piece 15 can drive reagent dish 2 through first gear 128 and rotate, through this kind of mode, the transmission of second driving piece 15 is steady, can control the rotational speed of detecting in-process reagent dish fixing base 121 accurately.

In this embodiment, the first driving member 127 is a dc motor, and the second driving member 15 is a stepping motor. Through using two driving pieces to drive reagent dish fixing base 121 respectively under different scenes and rotate, the overall performance requirement to the driving piece is lower, therefore, can reduce biochemical analyzer 100's manufacturing cost. In addition, the two driving members work separately, which can also prolong the service life of the driving members, thereby prolonging the service life of the biochemical analyzer 100.

Further, as shown in fig. 16, fig. 16 is a schematic structural diagram of another view angle of the biochemical analyzer in fig. 1, and the frame assembly 11 is provided with a first optical coupling assembly 171 for detecting whether the reagent disk fixing seat 121 is located at an eccentric position. The centrifugation component 12 may be provided with a first blocking piece 172, and when the first blocking piece 172 moves to the first optical coupling component 171, it can be confirmed that the reagent plate fixing seat 121 is located at the centrifugation position.

Further, a second optical coupler assembly 173 is further disposed on the frame assembly 11, and is used for detecting whether the reagent tray fixing seat 121 is located at the detection position. The centrifugal assembly 12 may be provided with a second stopper 174, and when the second stopper 174 moves to the second optical coupler assembly 173, it can be determined that the reagent disk fixing base 121 is located at the detection position.

The first and second optical coupler assemblies 171 and 173 may be respectively located at both ends of the centrifugal assembly 12, and the first and second stoppers 172 and 174 are respectively located on the first and second sliders 102 and 103. Thus, the first optical coupler assembly 171 and the second optical coupler assembly 173 do not interfere with each other, and the space of the frame assembly 11 can be reasonably utilized.

The biochemical analyzer 100 is simple in structure, small in size, capable of detecting a sample to be detected in the reagent tray 2, simple in detection process and high in reliability of detection results.

The biochemical analyzer 100 further includes a controller (not shown), the controller is connected to the centrifugal module 12, the light source module 13, the rear light splitting module 14, the second driving component 15 on the frame module 11, and the driving component 116, and the controller can control each module to automatically complete the detection process of the biochemical analyzer 100, and specifically, as shown in fig. 17, the controller can be used to implement the following detection method:

s11: and acquiring a warehouse-out instruction.

When a user needs to detect a sample to be detected, the sample to be detected is placed in the sample area of the reagent disk 2, and then the delivery button is clicked, so that the controller receives a delivery instruction.

S12: and driving the centrifugal assembly to move to the delivery position based on the delivery instruction so that a user places the reagent disk in the centrifugal assembly.

The controller drives the centrifuge assembly 12 to move to the delivery position based on the user's delivery instructions. Specifically, the controller controls the driving part 116 to drive the slide block 120 to move along the guide rail 110, so that the centrifugal assembly 12 moves to the unloading position, that is, the reagent disk fixing seat 121 moves to the outer side of the test cavity 113, so that the user can place the reagent disk 2 provided with the sample to be detected on the reagent disk fixing seat 121.

In particular, the driving member 116 may drive the centrifugal assembly 12 to move to the discharge position by means of the gear 117 and the rack 129.

S13: the centrifugal assembly is controlled to move to a centrifugal position, and the centrifugal assembly is controlled to drive the reagent disk fixing seat to rotate at a first rotating speed.

When the reagent disk 2 is placed in the centrifuge assembly 12, the controller drives the centrifuge assembly 12 to move to the centrifugation position via the drive member 116. Specifically, whether the centrifugal assembly 12 is in the centrifugal position or not can be determined by the first optical coupling assembly 171. When the centrifugation assembly 12 is in the centrifugation position, the controller controls the centrifugation assembly 12 to drive the reagent disk holder 121 to rotate at the first rotation speed. Specifically, the controller controls the first driving member 127 to drive the reagent disk fixing seat 121 to rotate at a first rotation speed so as to centrifuge the reagent disk 2, so that the sample to be detected enters the reagent hole in the reagent disk 2 to be detected, and the sample to be detected is detected. For the specific centrifugation step, reference is made to the following description of the examples.

S14: and controlling the centrifugal assembly to move to the detection position, and controlling the second driving piece to drive the reagent disk fixing seat to rotate at a second rotating speed.

After the centrifugation assembly 12 has centrifuged the reagent disk 2 in the centrifugation position, the controller drives the centrifugation assembly 12 to move to the detection position through the driving part 116, so as to detect the reagent disk 2.

Specifically, the driving member 116 may drive the centrifugal assembly 12 from the centrifugal position to the test position by means of the gear 117 and the rack 129.

After the centrifugal assembly 12 moves to the detection position, the controller controls the second driving member 15 to drive the reagent disk fixing seat 121 to rotate at the second rotation speed, and the reagent disk 2 rotates at the detection position at a low speed so that the light source assembly 13 emits a light beam through each reagent hole on the reagent disk 2. For the ranges of the first rotation speed and the second rotation speed, please refer to the description of the above embodiments, which is not repeated herein.

S15: and controlling the light source component to emit light beams which pass through the detection positions of the reagent disk.

When the centrifugal assembly 12 is located at the detection position, the controller controls the light source assembly 13 to emit a light beam while the reagent disk 2 rotates, and the light beam passes through the detection position of the reagent disk 2. The detection position of the reagent disk 2 refers to the reagent hole of the reagent disk 2, and the centrifugal assembly 12 drives the reagent disk 2 to rotate at a low speed so that the light beam can pass through each reagent hole on the reagent disk 2.

S16: the light beam passing through the detection position of the reagent disk is processed by the rear light splitting assembly for detection analysis.

After the light beam passes through the inspection position of the reagent disk 2, the rear spectroscopic assembly 14 performs a spectroscopic process on the light beam passing through the inspection position of the reagent disk 2 for detection analysis.

Specifically, after passing through the detection position of the reagent disk 2, the light beam propagates in the vertical direction, the rear light splitting assembly 14 adjusts the light beam propagating in the vertical direction to the horizontal direction by the reflective mirror 141, the light beam propagating in the horizontal direction sequentially passes through the plurality of light splitting sheets 142 to separate light with a specific wavelength, the light with the specific wavelength separated by the light splitting sheets 142 is subjected to filtering processing by corresponding optical filters, and the light passing through the optical filters is finally absorbed by corresponding photodiodes 143 for detection and analysis.

S17: and controlling the temperature adjusting assembly to work so that the temperature of the frame assembly is within a preset temperature range.

Throughout the process of detecting the sample to be detected in the reagent disk 2 by the biochemical analyzer 100, the controller may control the temperature adjustment assembly 16 to operate, so that the temperature in the frame assembly 11 is within a preset temperature range, that is, the reaction chamber of the reagent disk 2 may be kept at a constant temperature. Wherein the preset temperature setting is determined by the type of sample to be tested and the nature of the reagents in the reagent disk 2. For example, when the sample to be tested and the reagent need to react under a high temperature condition, the controller controls the temperature adjustment assembly 16 to operate, so that the temperature inside the frame assembly 11 reaches the required high temperature. For the structure of the temperature adjustment assembly 16, refer to the description of the above embodiments.

In summary, in the detection method of the biochemical analyzer 100 in the present application, after the reagent disk 2 is placed in the centrifugal component 12, the controller first controls the centrifugal component 12 to move to the centrifugal position, then the centrifugal component 12 drives the reagent disk 2 to rotate so as to centrifuge the reagent disk 2, a sample to be detected enters the reagent holes of the reagent disk 2 and is uniformly mixed with the reagents in the reagent holes, the driving component 116 drives the centrifugal component 12 to the detection position, in the detection position, the second driving component 15 drives the reagent disk 2 to rotate at a low speed, the light beams emitted by the light source component 13 sequentially pass through the detection positions of the reagent disk 2, and the light beam passing through the detection positions of the reagent disk 2 is subjected to light splitting by the light splitting component 14 for corresponding detection and analysis. The detection method is simple, does not need manual participation in the detection process, and is convenient for users to use; in the detection process, the temperature of the reaction bin can be kept constant through the temperature adjusting assembly 16, the accuracy of the detection result is improved, and the adaptability of the biochemical analyzer 100 to the environment is improved.

The biochemical analyzer 100 drives the reagent disk 2 to rotate at a high speed in the centrifugal position during the above-mentioned detection process, so as to centrifuge the reagent disk 2, and the method of centrifugation will be described in detail below by taking a certain reagent disk 2 as an example. The specific structure of the reagent disk 2 is shown in fig. 18, the reagent disk 2 includes a sample area 21 to be detected and a diluent area 22, the sample area 21 to be detected is provided with a sample to be detected, the diluent area 22 is provided with a diluent, and the reagent disk 2 further includes a sample quantifying area 26, a diluent quantifying area 25, a mixing area 23, and a plurality of reagent holes 24.

The controller of the biochemical analyzer 100 is connected to the centrifugation module 12, as shown in fig. 19, and is used for implementing the following centrifugation methods:

s21: the controller controls the centrifugal assembly to work in an accelerated centrifugation mode, so that a sample to be detected enters the sample quantifying area from the sample area to be detected, and diluent enters the diluent quantifying area from the diluent area.

After the centrifugal assembly 12 is in the centrifugal position, the controller first controls the centrifugal assembly 12 to operate in an accelerated centrifugal mode, wherein the accelerated centrifugal mode includes: the centrifugal component 12 drives the reagent tray to rotate at a high speed, the sample to be detected and the diluent in the reagent tray 2 do centrifugal motion, so that the sample to be detected in the reagent tray 2 enters the sample quantitative area 26, and the diluent in the reagent tray 2 enters the diluent quantitative area 25. Wherein, centrifugal component 12 drives reagent dish 2 and moves rotational speed and is greater than 4000 rpm, and in this embodiment, the rotational speed that centrifugal component 12 drove reagent dish 2 and moves is 5000 rpm. In other embodiments, the rotation speed of the centrifuge assembly 12 to move the reagent disk 2 may also be 4500 rpm.

In this embodiment, the sample to be tested is blood, and under the accelerated centrifugal motion of the reagent disk 2, the blood is separated into plasma and blood cells, the plasma enters the sample quantification region 26, the blood cells enter the collection region outside the sample orientation region, and the excess plasma enters the waste liquid region, so as to complete the separation of the blood. Practical tests have shown that the separation of blood cells and plasma can be achieved by accelerating the centrifugation of the reagent disk 2 for about 90 seconds. The diluent enters the diluent quantification region 25 from the diluent region 22 to achieve a predetermined ratio of diluent to plasma. The diluent may be water, and in other embodiments, the diluent may also be other solutions, and may be specifically selected and set according to the type of the sample to be detected.

S22: the controller controls the centrifugal assembly to work in an acceleration and deceleration centrifugal mode, so that a sample to be detected enters the mixing area from the sample quantifying area, diluent enters the mixing area from the diluent quantifying area, and the sample to be detected and the diluent are mixed in the mixing area to obtain a diluted sample.

After the sample to be tested and the diluent enter the respective quantitative regions, the controller controls the centrifuge assembly 12 to operate in an acceleration/deceleration centrifuge mode. Wherein, acceleration and deceleration centrifugation mode: the centrifugal assembly 12 first performs accelerated centrifugation to allow the sample to be detected to enter the mixing region 23 from the sample quantifying region 26, and the diluent enters the mixing region 23 from the diluent quantifying region 25, and then the centrifugal assembly 12 performs multiple times of accelerated centrifugation and decelerated centrifugation alternately to allow the sample to be detected and the diluent to be uniformly mixed in the mixing region 23, so as to obtain the diluted sample.

In this step, the sample to be measured and the diluent are more uniformly mixed in the mixing region 23 by accelerating and decelerating and centrifuging the reagent disk 2.

S23: the controller controls the centrifuge assembly to operate in a forward and reverse rotation centrifuge mode to cause the diluted sample to enter and mix with the reagents in the plurality of reagent wells.

The controller controls the centrifuge assembly 12 to operate in a forward and reverse rotation centrifuge mode, wherein the forward and reverse rotation centrifuge mode comprises: the controller first controls the centrifuge assembly 12 to centrifuge at a high speed to cause the diluted sample in the mixing zone 23 to enter the plurality of reagent wells 24. Wherein the reagent wells 24 hold corresponding reagents for detecting different items of the sample to be tested.

To avoid the effect of manual reagent change on the test efficiency during the test, it is common to allow multiple reagent wells 24 on the reagent disk 2, with multiple reagent wells 24 storing different reagents.

After the diluted sample enters the plurality of reagent wells 24, the centrifuge assembly 12 alternates between multiple cycles of forward and reverse rotation to allow the diluted sample to fully react with the reagents in the reagent wells 24. In this embodiment, the forward and reverse rotation may be performed in a mode of forward rotation for 1 second, reverse rotation for 1 second, and so on, and the cycle may be performed alternately for a preset number of times. In this way, the diluted sample can be sufficiently reacted with the reagent in the reagent well 24.

In this implementation, the centrifugation method of the centrifugation component 12 on the reagent disk is simple, can be automatically performed, has a high intelligent degree, and can improve the reliability of the detection of the sample to be detected by reasonably selecting the mode of driving the reagent disk to rotate in each centrifugation step.

Referring to fig. 20, fig. 20 is a schematic flow chart of another embodiment of a centrifugation method of a biochemical analyzer according to the present invention, in this embodiment, as shown in fig. 18, a first microchannel 201 is disposed between a sample quantifying region 26 and a mixing region 23, a second microchannel 202 is disposed between a diluent quantifying region 25 and the mixing region 23, and a third microchannel 203 is disposed between the mixing region 23 and a plurality of reagent wells 24, and the centrifugation method specifically includes:

s31: the controller controls the centrifugal assembly to work in an accelerated centrifugation mode, so that a sample to be detected enters the sample quantifying area from the sample area to be detected, and diluent enters the diluent quantifying area from the diluent area.

Step S31 is the same as step S21, and is not repeated here.

S32: the controller controls the centrifugal assembly to stop working, the reagent tray is made to stand for a first preset time, so that a sample to be detected in the sample quantification area enters the first micro-channel, and diluent in the diluent quantification area enters the second micro-channel.

The centrifugal component 12 can prevent the diluent and the sample to be detected from entering the mixing area 23 in advance by setting up a micro flow channel in the process of centrifuging the reagent disk 2 so as to ensure that the quantitative area can be accurately quantified, and thus, the ratio of the diluent and the sample to be detected is more accurate.

When the reagent disk 2 is kept still for a first predetermined time, as the first micro-channel 201 and the second micro-channel 202 can be subjected to hydrophobic treatment in advance through the hydrophobic material, during the standing period of the reagent disk 2, under the capillary action, the sample to be detected in the quantitative region enters the first micro-channel 201 and is filled with the first micro-channel 201, and the diluent enters the second micro-channel and is filled with the second micro-channel 202.

The first predetermined time is longer than 5s, in this embodiment, the first predetermined time is 10s, so that the sample to be detected and the diluent fill the first micro flow channel 201 and the second micro flow channel 202 under the capillary action.

S33: the controller controls the centrifugal assembly to work in an acceleration and deceleration centrifugal mode, so that a sample to be detected enters the mixing area from the sample quantifying area, diluent enters the mixing area from the diluent quantifying area, and the sample to be detected and the diluent are mixed in the mixing area to obtain a diluted sample.

Step S33 is the same as step S22, and is not repeated here.

S34: and the controller controls the centrifugal assembly to stop working, and the reagent tray is allowed to stand for a second preset time so that the diluted sample in the mixing area enters the third micro-channel.

The third microchannel may also be subjected to hydrophobic treatment in advance, so that the diluent in the mixing region enters the third microchannel 203 and fills the third microchannel 203 during the second predetermined time period when the centrifugal assembly is standing.

The second predetermined time period is greater than 5s, in this embodiment, the second predetermined time period is 10s, and in other embodiments, the second predetermined time period may be set to other times according to the structure, length, and the like of the micro flow channel.

S35: the controller controls the centrifuge assembly to operate in a forward and reverse rotation centrifuge mode to cause the diluted sample to enter and mix with the reagents in the plurality of reagent wells.

Step S35 is the same as step S23, and is not repeated here.

S36: the controller controls the centrifuge assembly to rotate the reagent disk at a constant speed for a predetermined time to cause the air bubbles of the liquid in the plurality of reagent wells to be expelled.

When the reagent in the reagent well 24 and the diluted sample are sufficiently reacted, air bubbles may be present in the reagent well 24, and then the controller controls the centrifugation component 12 to rotate at a high speed for a period of time, specifically, the controller may control the centrifugation component 12 to drive the reagent disk 2 to rotate at a constant speed for a predetermined time, so as to discharge the air bubbles of the reagent reacted with the sample to be detected from the air discharge hole.

In summary, in the centrifugation method of the present embodiment, by providing the micro flow channel, the sample can not enter the next stage in advance, so that the centrifugation process of each stage is more reliable, and the reliability of the overall test of the biochemical analyzer can be improved.

The above description is only for the purpose of illustrating embodiments of the present application and is not intended to limit the scope of the present application, and all modifications of equivalent structures and equivalent processes, which are made by the contents of the specification and the drawings of the present application or are directly or indirectly applied to other related technical fields, are also included in the scope of the present application.

Claims (10)

1. A biochemical analyzer, comprising:

the frame assembly is provided with a guide rail;

the centrifugal assembly is arranged on the frame assembly and used for bearing the reagent disk and driving the reagent disk to rotate so as to enable the reagent disk to do centrifugal motion, and a sliding block is arranged on the centrifugal assembly and is arranged with the guide rail in a sliding mode.

2. The biochemical analyzer according to claim 1, further comprising a driving member connected to the slider for driving the slider to slide along the guide rail.

3. The biochemical analyzer according to claim 2, wherein the driving member includes a gear, and the slider is provided with a rack, and the gear is engaged with the rack so that the driving member drives the slider to move.

4. The biochemical analyzer according to claim 1, wherein the guide rail comprises a first guide rail and a second guide rail, the first guide rail and the second guide rail are disposed on the frame assembly in parallel and spaced apart, the slider comprises a first slider and a second slider, the first slider is slidably disposed with the first guide rail, and the second slider is slidably disposed with the second guide rail.

5. The biochemical analyzer according to claim 1, wherein the frame assembly includes a bracket and a holder, the holder being carried on the bracket, the holder being formed with a test chamber for receiving the centrifuge assembly.

6. The biochemical analyzer according to claim 5, wherein a first opening is disposed on a side wall of the test chamber, the guide rail extends in a direction perpendicular to a plane of the first opening, and the centrifuge assembly enters and exits the test chamber through the first opening.

7. The biochemical analyzer of claim 6, wherein a side of the centrifuge assembly away from the test chamber is provided with a cover plate for sealing the first opening.

8. The biochemical analyzer according to claim 5, wherein a second opening is disposed on a bottom wall of the testing chamber, and the centrifugation assembly includes a first driving member for driving the reagent disk to rotate, the first driving member being inserted into the second opening.

9. The biochemical analyzer of claim 1, further comprising a limiting plate located at one side of the rail.

10. The biochemical analyzer according to claim 1, wherein a card board is disposed on the centrifugation assembly, and a stopper is disposed on the frame assembly, the stopper being located on one side of the card board for blocking the passage of the card board.

Images