CN215812811U

CN215812811U - Multi-channel fluorescence immunoassay analyzer

Info

Publication number: CN215812811U
Application number: CN202122088339.XU
Authority: CN
Inventors: 刘忠; 刘青平; 刘春丽; 王金龙; 唐妍
Original assignee: Shandong Xinqiao Liankang Bioengineering Co ltd
Current assignee: Shandong Xinqiao Liankang Bioengineering Co ltd
Priority date: 2021-09-01
Filing date: 2021-09-01
Publication date: 2022-02-11
Anticipated expiration: 2031-09-01

Abstract

The utility model discloses a multi-channel fluorescence immunoassay analyzer, which comprises a base, reagent card mounting plates are symmetrically and rotatably arranged on two sides of the base, grooves are formed on one opposite sides of the two reagent card mounting plates, a plurality of reagent card slots for storing reagent cards are arranged in the grooves at equal intervals along the length direction of the base, and the multi-channel fluorescence immunoassay analyzer also comprises a scanning detection device arranged above the base, wherein the two reagent card mounting plates rotate by 90 degrees to be opposite to each other, and the scanning detection device moves along the length direction of the base to scan and detect the reagent cards in the two reagent card mounting plates. According to the multi-channel fluorescence immunoassay analyzer, the scanning detection device slides on the guide rail to simultaneously complete the detection of the two reagent cards, and the detection channels of the reagent cards are multiplied while the detection time is not increased, so that the detection efficiency is improved.

Description

Multi-channel fluorescence immunoassay analyzer

Technical Field

The utility model relates to the technical field of fluorescence immunoassay analyzers, in particular to a multi-channel fluorescence immunoassay analyzer.

Background

Most of the existing fluorescence analyzers are single-channel devices; obviously, the single-channel detection equipment has low efficiency and low speed, and when the sample size is large, the single-channel equipment cannot meet the detection requirement. Although a plurality of multi-channel fluorescence immunoassay analyzers are also disclosed in the prior art, the detection channels are only improved on one device, the detection device still needs to sequentially pass through each detection channel to detect the reagent card one by one, the detection continuity can be improved, but the detection speed and the detection efficiency can not be effectively improved by adopting a one-by-one detection mode in the face of a plurality of detection channels, the existing reagent card is inconvenient to install and disassemble, and the detection efficiency can be influenced to a certain extent.

SUMMERY OF THE UTILITY MODEL

The present invention is directed to solving, at least to some extent, one of the technical problems in the related art. Therefore, an object of the present invention is to provide a multi-channel fluorescence immunoassay analyzer, in which a scanning detection device slides on a guide rail to simultaneously complete the detection of two reagent cards, and the detection channels of the reagent cards are multiplied without increasing the detection time, thereby improving the detection efficiency.

The utility model provides a multi-channel fluorescence immunoassay analyzer, which comprises a base, reagent card mounting plates symmetrically and rotatably arranged on two sides of the base, grooves formed on opposite sides of the two reagent card mounting plates, and a scanning detection device arranged above the base, wherein a plurality of reagent card slots for storing reagent cards are arranged in the grooves at equal intervals along the length direction of the base, and the scanning detection device moves along the length direction of the base to scan and detect the reagent cards in the two reagent card mounting plates when the two reagent card mounting plates rotate by 90 degrees to face each other.

Preferably, the middle parts of the two ends of the base are connected with support frames along the vertical direction, guide rails are connected between the tops of the two support frames through support rods, and the scanning detection device is arranged on the guide rails in a sliding mode.

Preferably, the scanning detection device comprises a sliding block and a mounting piece; all install the light source on the bottom both sides wall of installation piece, the middle part of slider link up and set up the guide way with guide rail looks adaptation, and scanning detection device passes through guide way slidable mounting on the guide rail.

Preferably, the top of slider is formed with the mounting groove, and the internal rotation of mounting groove installs sector gear, is fixed with the motor on the outer wall of slider, and the output pivot of motor runs through behind the slider with sector gear's center pin fixed connection, and the top parallel arrangement of guide rail has the rack, and the both ends of rack link to each other with the top of vaulting pole respectively, and the rack meshes with sector gear mutually to sector gear and rack are in a meshing transmission cycle, and the distance that the slider moved along the base is the same with the distance between two adjacent reagent cards.

Preferably, the bottoms of the two sides of each reagent card mounting plate are respectively connected with a first fixing piece through bolts, the two ends of the base along the length direction of the base are respectively connected with a second fixing piece through bolts, the bottom of the first fixing piece is fixedly connected with a second connecting rod along the inclined direction, the outer end face of the second fixing piece is rotatably connected with a first rotating plate and a second rotating plate, and first rotor plate and second rotor plate parallel arrangement, the one end relative with the link on the second connecting rod rotates and is connected with first connecting rod, the other end of first connecting rod rotates with the bottom of first rotor plate to be connected, the middle part of first connecting rod rotates with the bottom of second rotor plate to be connected, the top of second rotor plate is followed the direction slope extension towards first rotor plate and is formed with the pole of buckling, it has the third connecting rod to articulate between the end of pole of buckling and the top of second connecting rod, the first connecting rod and the third connecting rod of the section between second rotor plate and the second connecting rod are parallel.

The utility model also provides a using method of the fluorescence immunoassay analyzer, which comprises the following steps: in an initial state, two reagent card mounting plates are horizontally arranged on two sides of a base, reagent cards to be detected are respectively inserted into corresponding reagent card slots, then the two reagent card mounting plates are rotated by 90 degrees to be opposite, the scanning detection device is arranged at the starting end of the guide rail, the light source corresponds to the first group of reagent cards, after the scanning detection device finishes the detection of the first group of reagent cards, the starting motor drives the sector gear to rotate, the sector gear is meshed with the rack to drive the sliding block to slide along the guide rail, when the sector gear and the rack complete an engagement period, the light source just corresponds to the second group of reagent cards, the sector gear and the rack generate an idle stroke, the scanning detection device completes detection on the second group by using the time of the idle stroke, and the sector gear is engaged with the rack again to drive the scanning detection device to slide along the guide rail to the next group of reagent cards until the scanning detection device completes detection on all the reagent cards.

The beneficial effects of the utility model are as follows: according to the multi-channel fluorescence immunoassay analyzer, the reagent card slots for installing the reagent cards are distributed on the reagent card installing plate, the installing plate is rotatably installed on two sides of the scanning detection device, when the reagent card installing plate is horizontally placed, personnel can conveniently install the reagent cards, when the reagent cards need to be detected, the reagent card installing plate is rotated to be in a vertical state, the scanning detection device slides on the guide rail to simultaneously complete detection of the two reagent cards, the detection channels of the reagent cards are multiplied while the detection time is not increased, and therefore the detection efficiency is improved. In addition, when the scanning detection device moves on the guide rail, the sector gear and the rack are intermittently meshed to drive the scanning detection device to move, and the detection of the reagent card is completed by utilizing the idle stroke period of the sector gear and the rack, so that the frequent starting of the motor can be avoided, and the service life of the motor can be effectively prolonged.

Drawings

The accompanying drawings, which are included to provide a further understanding of the utility model and are incorporated in and constitute a part of this specification, illustrate embodiments of the utility model and together with the description serve to explain the principles of the utility model and not to limit the utility model. In the drawings:

FIG. 1 is a schematic diagram of the overall structure of the multi-channel fluorescence immunoassay analyzer of the present invention;

FIG. 2 is a partial schematic view of the present invention;

FIG. 3 is a front view of the multi-channel fluorescence immunoassay analyzer of the present invention;

FIG. 4 is a schematic structural diagram of a scanning detection apparatus according to the present invention;

fig. 5 is a partially enlarged schematic view of a portion a in fig. 1.

In the figure: 1. a base; 2. a support frame; 3. a stay bar; 4. a rack; 5. a guide rail; 6. a scanning detection device; 61. mounting a sheet; 62. a light source; 63. a slider; 64. a guide groove; 65. mounting grooves; 66. a sector gear; 67. a motor; 7. a reagent card mounting plate; 8. a groove; 9. a reagent card slot; 10. a reagent card; 11. a first fixing sheet; 12. a second fixing sheet; 13. a first rotating plate; 14. a second rotating plate; 15. a first link; 16. a second link; 17. a third link; 18. the rod is bent.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments.

Examples of which are illustrated in the accompanying drawings, wherein like reference numerals refer to the same or similar elements or elements having the same or similar function throughout. The embodiments described below with reference to the drawings are illustrative and intended to be illustrative of the utility model and are not to be construed as limiting the utility model.

In the description of the present invention, it is to be understood that the terms "central," "longitudinal," "lateral," "length," "width," "thickness," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," "clockwise," "counterclockwise," "axial," "radial," "circumferential," and the like are used in the orientations and positional relationships indicated in the drawings for convenience in describing the utility model and to simplify the description, and are not intended to indicate or imply that the referenced devices or elements must have a particular orientation, be constructed and operated in a particular orientation, and are therefore not to be considered limiting of the utility model.

Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of the present invention, "a plurality" means two or more unless specifically defined otherwise.

In the present invention, unless otherwise expressly stated or limited, the terms "mounted," "connected," "secured," and the like are to be construed broadly and can, for example, be fixedly connected, detachably connected, or integrally formed; can be mechanically or electrically connected; either directly or indirectly through intervening media, either internally or in any other relationship. The specific meanings of the above terms in the present invention can be understood by those skilled in the art according to specific situations.

As shown in fig. 1-5, the embodiment discloses a multi-channel fluorescence immunoassay analyzer, which includes a base 1, reagent card mounting plates 7 are symmetrically and rotatably disposed on two sides of the base 1, a groove 8 is formed on each of the opposite sides of the two reagent card mounting plates 7, a plurality of reagent card slots 9 for storing reagent cards 10 are disposed in the groove 8 at equal intervals along the length direction of the base 1, and a scanning detection device 6 is disposed above the base 1, the scanning detection device 6 adopts the well-established technology, generates emitted light, irradiates on the reagent cards 10, and collects the reflected light of the reagent cards 10, a signal collection converter in the scanning detection device 6 can convert the reflected light signals collected by a scanning detection system into electrical signals, and processes and detects the fluorescence intensity of the reagent cards through photoelectric signals, the two reagent card mounting plates 7 rotate 90 ° to face each other, the scanning detection device 6 moves along the length direction of the base 1 and sequentially passes through the reagent card slots 9 in the two reagent card mounting plates 7, thereby completing the scanning detection of the reagent cards 10.

Specifically, as shown in fig. 1, the middle parts of the two ends of the base 1 are connected with the support frames 2 along the vertical direction, the tops of the two support frames 2 are connected with a guide rail 5 through the support rods 3, and the scanning detection device 6 is arranged on the guide rail 5 in a sliding manner.

Further, as shown in fig. 4, the scanning detection device 6 in the present embodiment includes a slider 63 and a mounting piece 61; the two side walls of the bottom of the mounting piece 61 are both provided with light sources 62, the light sources 62 are used for generating reflected light, the middle part of the sliding block 63 is provided with a guide groove 64 matched with the guide rail 5 in a penetrating way, and the scanning detection device 6 is slidably mounted on the guide rail 5 through the guide groove 64.

In order to enable the scanning detection device 6 to scan each group of reagent cards 10 when moving along the guide rail 5, the utility model forms a mounting groove 65 on the top of the sliding block 63, a sector gear 66 is rotatably mounted inside the mounting groove 65, a motor 67 is fixed on the outer wall of the sliding block 63, the output rotating shaft of the motor 67 penetrates through the sliding block 63 and is fixedly connected with the central shaft of the sector gear 66, a rack 4 is arranged above the guide rail 5 in parallel, two ends of the rack 4 are respectively connected with the top end of the stay bar 3, the rack 4 is meshed with the sector gear 66, the sector gear 66 is driven to rotate by the motor 67, the sector gear 66 is in intermittent meshing transmission with the rack 4, and further drives the sliding block 63 to slide along the guide rail 5, and the sector gear 66 and the rack 4 move along the base 1 for the same distance as the distance between two adjacent reagent cards 10 in one meshing transmission period, therefore, when the sector gear 66 is engaged with the rack 4, the slide block 63 moves between the two reagent cards 10, and when the sector gear 66 and the rack 4 are in the idle stroke state, the scanning detection device 6 completes the detection of the shuffled reagent cards 10.

In addition, as shown in fig. 5, a first fixing plate 11 is bolted on the bottom of each reagent card mounting plate 7 at both sides, a second fixing plate 12 is bolted on both ends of the base 1 along the length direction thereof, a second connecting rod 16 is fixedly connected on the bottom of the first fixing plate 11 along the oblique direction, a first rotating plate 13 and a second rotating plate 14 are rotatably connected on the outer end surface of the second fixing plate 12, the first rotating plate 13 and the second rotating plate 14 are arranged in parallel, a first connecting rod 15 is rotatably connected on one end of the second connecting rod 16 opposite to the connecting end, the other end of the first connecting rod 15 is rotatably connected with the bottom end of the first rotating plate 13, the middle part of the first connecting rod 15 is rotatably connected with the bottom of the second rotating plate 14, a bending rod 18 is formed by extending the top end of the second rotating plate 14 obliquely in the direction toward the first rotating plate 13, a third connecting rod 17 is hinged between the end of the bending rod 18 and the top end of the second connecting rod 16, the first connecting rod 15 between the second rotating plate 14 and the second connecting rod 16 is parallel to the third connecting rod 17, when the two reagent card mounting plates 7 are rotated from the horizontal state to the vertical state, the first rotating plate 13 and the second rotating plate 14 simultaneously rotate clockwise, and then the first connecting rod 15 drives the second connecting rod 16 to rotate clockwise, while the second connecting rod 16 is fixedly connected with the reagent card mounting plates 7, and the bending rod 18 at the top end of the second rotating plate 14 applies acting force to the third connecting rod 17 due to counterclockwise rotation, and the second connecting rod 16 drives the reagent card mounting plate 7 to rotate by taking the bottom of the reagent card mounting plate as the center under the matching action of the first connecting rod 15 and the third connecting rod 17.

The utility model provides a multi-channel fluorescence immunoassay analyzer, which has the detailed working principle that: in an initial state, two reagent card mounting plates 7 are horizontally arranged on two sides of a base 1, reagent cards 10 to be detected are respectively inserted into corresponding reagent card slots 9, then the two reagent card mounting plates 7 are rotated ninety degrees to be opposite, a scanning detection device 6 is arranged at the initial end of a guide rail 5, a light source 62 corresponds to a first group of reagent cards 10, after the scanning detection device 6 finishes the detection of the first group of reagent cards 10, a motor 67 is started to drive a sector gear 66 to rotate, the sector gear 66 is meshed with a rack 4 to further drive a sliding block 63 to slide along the guide rail 5, after the sector gear 66 finishes a meshing period with the rack 4, the light source 62 just corresponds to a second group of reagent cards 10, the sector gear 66 and the rack 4 generate an idle stroke, the scanning detection device 6 finishes the detection of the second group 10 by utilizing the time of the idle stroke, the sector gear 66 is meshed with the rack 4 again to drive the scanning detection device 6 to slide along the guide rail 5 to a next group of reagent cards 10, until the scanning detection device 6 completes the detection of all the reagent cards 10.

The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and equivalent alternatives or modifications according to the technical solution of the present invention and the inventive concept thereof should be covered by the scope of the present invention.

Claims

1. The utility model provides a multichannel fluorescence immunoassay appearance, a serial communication port, including base (1), the rotation of the bilateral symmetry of base (1) is provided with reagent card mounting panel (7), one side that two reagent card mounting panels (7) are relative all is formed with recess (8), the inside of recess (8) is along the equidistant reagent card slot (9) of installing a plurality of reagent cards (10) that are used for depositing of the length direction of base (1), still including setting up in scanning detection device (6) of base (1) top, two reagent card mounting panels (7) are rotatory 90 to when mutually opposing, scanning detection device (6) are moved and are scanned the detection to reagent card (10) inside two reagent card mounting panels (7) along the length direction of base (1).

2. The multi-channel fluorescence immunoassay analyzer of claim 1, wherein the middle parts of the two ends of the base (1) are connected with the support frames (2) along the vertical direction, the top parts of the two support frames (2) are connected with the guide rail (5) through the support rods (3), and the scanning detection device (6) is arranged on the guide rail (5) in a sliding manner.

3. A multi-channel fluoroimmunoassay analyzer according to claim 2, wherein the scanning detecting means (6) comprises a slider (63) and a mounting plate (61); light sources (62) are mounted on two side walls of the bottom of the mounting piece (61), a guide groove (64) matched with the guide rail (5) is formed in the middle of the sliding block (63) in a penetrating mode, and the scanning detection device (6) is mounted on the guide rail (5) in a sliding mode through the guide groove (64).

4. The multi-channel fluorescence immunoassay analyzer according to claim 3, wherein a mounting groove (65) is formed at the top of the sliding block (63), a sector gear (66) is rotatably mounted inside the mounting groove (65), a motor (67) is fixed on the outer wall of the sliding block (63), an output rotating shaft of the motor (67) penetrates through the sliding block (63) and then is fixedly connected with a central shaft of the sector gear (66), a rack (4) is arranged above the guide rail (5) in parallel, two ends of the rack (4) are respectively connected with the top end of the stay bar (3), the rack (4) is meshed with the sector gear (66), the sector gear (66) and the rack (4) are in a meshing transmission period, and the moving distance of the sliding block (63) along the base (1) is the same as the distance between two adjacent reagent cards (10).

5. The multi-channel fluorescence immunoassay instrument according to any one of claims 1 to 4, wherein the bottom of both sides of each reagent card mounting plate (7) is bolted with a first fixing plate (11), the two ends of the base (1) along the length direction thereof are bolted with second fixing plates (12), the bottom of the first fixing plate (11) is fixedly connected with a second connecting rod (16) along the inclined direction, the outer end surface of the second fixing plate (12) is rotatably connected with a first rotating plate (13) and a second rotating plate (14), the first rotating plate (13) and the second rotating plate (14) are arranged in parallel, one end of the second connecting rod (16) opposite to the connecting end is rotatably connected with a first connecting rod (15), the other end of the first connecting rod (15) is rotatably connected with the bottom end of the first rotating plate (13), the middle part of the first connecting rod (15) is rotatably connected with the bottom of the second rotating plate (14), the top end of the second rotating plate (14) obliquely extends towards the first rotating plate (13) to form a bending rod (18), a third connecting rod (17) is hinged between the tail end of the bending rod (18) and the top end of the second connecting rod (16), and the first connecting rod (15) between the second rotating plate (14) and the second connecting rod (16) is parallel to the third connecting rod (17).