CN215428759U

CN215428759U - Protein purification preprocessing device

Info

Publication number: CN215428759U
Application number: CN202121686179.2U
Authority: CN
Inventors: 刘诗洋; 刘挺; 宋梦薇
Original assignee: BEIJING SAISHENG PHARMACEUTICAL CO LTD
Current assignee: BEIJING SAISHENG PHARMACEUTICAL CO LTD
Priority date: 2021-07-23
Filing date: 2021-07-23
Publication date: 2022-01-07
Anticipated expiration: 2031-07-23

Abstract

The utility model discloses a protein purification pretreatment device, which comprises a workbench, wherein a rack is arranged on the workbench, a group of vertically downward air cylinders is arranged at the top of the rack, a mounting plate is arranged at the telescopic end of each air cylinder, a first motor is arranged on the mounting plate, the output end of the first motor penetrates through the mounting plate and is provided with a driving gear, a plurality of groups of stirring shafts are arranged at the bottom end of the mounting plate, driven gears are arranged at the tops of the groups of stirring shafts, the driving gear is mutually meshed with the driven gears, a rotary table is arranged on the workbench, a plurality of stirring tanks are arranged on the rotary table through a connecting mechanism, and the stirring tanks correspond to the stirring shafts one by one. The utility model is convenient to prepare a plurality of raw material samples at the same time, saves the working time and improves the working efficiency.

Description

Protein purification preprocessing device

Technical Field

The utility model relates to a protein treatment device, in particular to a protein purification pretreatment device.

Background

The separation and purification of proteins is widely used in biochemical research applications and is an important operation technology. A typical eukaryotic cell may contain thousands of different proteins, some very abundant, some containing only a few copies. To study a protein, the protein must first be purified from other proteins and non-protein molecules.

The raw materials need to be pulped before protein separation and purification, most of the conventional pulping devices are single and are used for mashing one material, when a plurality of raw materials or the same raw material is required to be prepared into a sample in a grouping manner, the raw materials need to be stirred one by one, the waiting visual angle is longer, the downtime required by adding and discharging the materials in the using process is also longer, and the efficiency of protein purification treatment is influenced. Therefore, we improve this and propose a pretreatment device for protein purification.

SUMMERY OF THE UTILITY MODEL

In order to solve the technical problems, the utility model provides the following technical scheme:

the protein purification pretreatment device comprises a workbench, wherein a rack is installed on the workbench, a vertically downward air cylinder is installed at the top of the rack, an installation plate is arranged at the telescopic end of the air cylinder, a first motor is installed on the installation plate, the output end of the first motor penetrates through the installation plate and is provided with a driving gear, a plurality of groups of stirring shafts are arranged at the bottom end of the installation plate, driven gears are installed at the tops of the groups of stirring shafts, the driving gear is mutually meshed with the driven gears, a rotary table is installed on the workbench, a plurality of stirring tanks are installed on the rotary table through a connecting mechanism, and the stirring tanks correspond to the stirring shafts in a one-to-one mode.

As a preferable technical scheme of the utility model, the rack comprises four support columns symmetrically arranged at two sides of the workbench, the top ends of the four support columns are provided with the same support plate, and the air cylinder is arranged at the bottom end of the support plate.

As a preferred technical scheme of the utility model, a sliding rod is arranged between every two supporting columns, and sliding blocks which are connected with the sliding rods in an inserting mode are arranged at two ends of the mounting plate.

As a preferable technical scheme of the utility model, the bottom end of the mounting plate is fixedly connected with a cover plate, and a plurality of groups of stirring shafts are vertically arranged below the cover plate.

As a preferable technical scheme of the utility model, the bottom end of the workbench is provided with a second motor, the output end of the second motor penetrates through the workbench to be connected with the rotary table, and the bottom end of the rotary table is connected with the upper surface of the workbench in a sliding manner.

According to a preferable technical scheme of the utility model, a plurality of placing grooves are formed in the top of the rotary table, the placing grooves are arranged in an equidistant annular shape, the stirring tanks correspond to the placing grooves one by one, and the bottoms of the stirring tanks are attached to the inner walls of the placing grooves.

As a preferable technical scheme of the utility model, a plurality of threaded columns are arranged at the top of the outer side of the rotary table, the plurality of threaded columns correspond to the plurality of placing grooves one by one, and the inner ends of the threaded columns are abutted against the outer side of the stirring tank.

The utility model has the beneficial effects that:

1. this protein purification preprocessing device rotates through first motor drive driving gear, and driving gear and a plurality of driven gear intermeshing drive a plurality of driven gear synchronous rotations for a plurality of (mixing) shafts are worked as and are stirred the garrulous processing to the raw materials in the stirring jar in step, stir simultaneously through putting into multiple raw and other materials in a plurality of stirring jars, take off the stirring jar again after the stirring is accomplished, conveniently prepare multiple raw materials sample, practiced thrift operating time, improved work efficiency.

2. This protein purification preprocessing device, through setting up the revolving stage, the second motor drive revolving stage rotates, and the installation is taken off the agitator tank to the in-process of conveniently going up unloading, practices thrift the labour, and sets up the standing groove that corresponds with the agitator tank on the revolving stage, and convenient quick accurate placing of agitator tank stirs on the revolving stage and handles, and improves the stability of agitator tank through the screw thread post on the revolving stage, and convenient quick takes off the agitator tank in order to use stirring garrulous raw materials.

Drawings

The accompanying drawings, which are included to provide a further understanding of the utility model and are incorporated in and constitute a part of this specification, illustrate embodiments of the utility model and together with the description serve to explain the principles of the utility model and not to limit the utility model. In the drawings:

FIG. 1 is a schematic view of the structure of a pretreatment apparatus for protein purification according to the present invention;

FIG. 2 is a schematic view of the structure of a turntable of the protein purification pretreatment apparatus of the present invention;

FIG. 3 is a front view of the work table of the protein purification pretreatment device of the present invention;

FIG. 4 is a schematic view of a partial structure of a housing of the protein purification pretreatment apparatus of the present invention.

In the figure: 1. a work table; 2. a frame; 3. a cylinder; 4. mounting a plate; 5. a first motor; 6. a driving gear; 7. a stirring shaft; 8. a driven gear; 9. a turntable; 10. a stirring tank; 11. a support pillar; 12. a support plate; 13. a slide bar; 14. a slider; 15. a cover plate; 16. a second motor; 17. a placement groove; 18. a threaded post.

Detailed Description

The preferred embodiments of the present invention will be described in conjunction with the accompanying drawings, and it will be understood that they are described herein for the purpose of illustration and explanation and not limitation.

Example (b): as shown in fig. 1, 2, 3 and 4, the protein purification pretreatment device comprises a workbench 1, wherein a rack 2 is installed on the workbench 1, a group of vertically downward cylinders 3 is installed at the top of the rack 2, an installation plate 4 is arranged at the telescopic end of each cylinder 3, a first motor 5 is installed on the installation plate 4, the output end of the first motor 5 penetrates through the installation plate 4 and is provided with a driving gear 6, a plurality of stirring shafts 7 are arranged at the bottom end of the installation plate 4, driven gears 8 are installed at the tops of the stirring shafts 7, the driving gear 6 is meshed with the driven gears 8, a rotary table 9 is installed on the workbench 1, a plurality of stirring tanks 10 are installed on the rotary table through a connecting mechanism, and the stirring tanks 10 are in one-to-one correspondence with the stirring shafts 7.

Wherein, frame 2 includes that four symmetries set up the support column 11 in workstation 1 both sides, and the top of four support columns 11 is provided with same backup pad 12, and cylinder 3 installs in the bottom of backup pad 12, makes things convenient for cylinder 3 to work.

Wherein, all be provided with slide bar 13 between per two support columns 11, the both ends of mounting panel 4 all are provided with the slider 14 of being connected with slide bar 13 interlude, improve the stability of mounting panel 4 lift in-process.

Wherein, the bottom fixedly connected with apron 15 of mounting panel 4, the equal vertical setting of multiunit (mixing) shaft 7 is in the below of apron 15, starts cylinder 3 for in mounting panel 4 descends and makes (mixing) shaft 7 get into agitator tank 10 along with cylinder 3, apron 15 and the top laminating of agitator tank 10 realize the sealing treatment to agitator tank 10.

Wherein, second motor 16 is installed to the bottom of workstation 1, and second motor 16's output passes workstation 1 and is connected with revolving stage 9, and revolving stage 9's bottom and 1 upper surface sliding connection of workstation, second motor 16 drive revolving stage 9 rotate, conveniently take off the installation with agitator tank 10 in the in-process of material loading and unloading, practice thrift the labour.

Wherein, a plurality of standing grooves 17 have been seted up at the top of revolving stage 9, and a plurality of standing grooves 17 are the equidistance annular setting, and a plurality of agitator tanks 10 and a plurality of standing grooves 17 one-to-one and agitator tank 10's bottom and standing groove 17's inner wall laminating, convenient quick with agitator tank 10 accurate place carry out stirring processing on revolving stage 9.

Wherein, the top in the revolving stage 9 outside is provided with a plurality of screw thread posts 18, a plurality of screw thread posts 18 and a plurality of standing groove 17 one-to-one, and the inner butt in the outside of screw thread post 18 and agitator tank 10 has improved agitator tank 10's stability.

The working principle is that a plurality of stirring tanks 10 are sequentially placed in a placing groove 17 on a rotary table 9, in the process, a second motor 16 can be started to drive the rotary table 9 to rotate, the stirring tanks 10 are convenient to place, threaded columns 18 are screwed after the stirring tanks 10 are placed, the inner ends of the threaded columns are abutted to the stirring tanks 10, the stability of the stirring tanks 10 is improved, in the process of starting a cylinder 3, a mounting plate 4 descends along with the cylinder 3, a stirring shaft 7 enters the stirring tanks 10, a cover plate 15 is attached to the top of the stirring tanks 10, a first motor 5 is started, the first motor 5 drives a driving gear 6 to rotate, the driving gear 6 is meshed with a plurality of driven gears 8 to drive the driven gears 8 to synchronously rotate, the stirring shafts 7 synchronously work in the stirring tanks 10 to stir raw materials, multiple raw materials are placed in the stirring tanks 10 to be simultaneously stirred, and the stirring tanks 10 are taken down after the stirring is finished, after the stirring is finished, the mounting plate 4 is driven to ascend to the initial position through the contraction of the air cylinder 3, the threaded column 18 is screwed out to enable the threaded column to be separated from the stirring tank 10, all the stirring tanks 10 can be taken down, the working time is saved, and the working efficiency is improved.

Finally, it should be noted that: although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that changes may be made in the embodiments and/or equivalents thereof without departing from the spirit and scope of the utility model. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. The protein purification pretreatment device comprises a workbench (1) and is characterized in that a rack (2) is arranged on the workbench (1), a vertically downward cylinder (3) is installed at the top of the frame (2), a mounting plate (4) is arranged at the telescopic end of the cylinder (3), a first motor (5) is arranged on the mounting plate (4), the output end of the first motor (5) penetrates through the mounting plate (4) and is provided with a driving gear (6), a plurality of groups of stirring shafts (7) are arranged at the bottom end of the mounting plate (4), driven gears (8) are arranged at the tops of the stirring shafts (7), the driving gear (6) is meshed with a plurality of driven gears (8), a rotary table (9) is arranged on the workbench (1), a plurality of stirring tanks (10) are installed on the rotary table through connecting mechanisms, and the stirring tanks (10) are in one-to-one correspondence with the stirring shafts (7).

2. The protein purification pretreatment device of claim 1, wherein the frame (2) comprises four support columns (11) symmetrically arranged at two sides of the workbench (1), the top ends of the four support columns (11) are provided with the same support plate (12), and the air cylinder (3) is arranged at the bottom end of the support plate (12).

3. The protein purification pretreatment device according to claim 2, wherein a sliding rod (13) is arranged between each two support columns (11), and sliding blocks (14) which are connected with the sliding rods (13) in a penetrating manner are arranged at two ends of the mounting plate (4).

4. The protein purification pretreatment device of claim 1, wherein a cover plate (15) is fixedly connected to the bottom end of the mounting plate (4), and the stirring shafts (7) are vertically arranged below the cover plate (15).

5. The protein purification pretreatment device according to claim 1, wherein a second motor (16) is installed at the bottom end of the workbench (1), the output end of the second motor (16) penetrates through the workbench (1) to be connected with the rotary table (9), and the bottom end of the rotary table (9) is slidably connected with the upper surface of the workbench (1).

6. The protein purification pretreatment device according to claim 1, wherein a plurality of placing grooves (17) are formed in the top of the rotary table (9), the placing grooves (17) are arranged in an equidistant annular shape, the stirring tanks (10) correspond to the placing grooves (17) one by one, and the bottoms of the stirring tanks (10) are attached to the inner walls of the placing grooves (17).

7. The protein purification pretreatment device according to claim 6, wherein a plurality of threaded columns (18) are arranged on the top of the outer side of the rotary table (9), the plurality of threaded columns (18) correspond to the plurality of placing grooves (17) one by one, and the inner ends of the threaded columns (18) are abutted against the outer side of the stirring tank (10).