CN214485740U

CN214485740U - Automatic positive-pressure column passing device for solid-phase extraction column

Info

Publication number: CN214485740U
Application number: CN202023273422.6U
Authority: CN
Inventors: 孙敦元; 杨蓉莉; 孙昕
Original assignee: Nanjing Laura Suel Electronics Co ltd
Current assignee: Nanjing Laura Suel Electronics Co ltd
Priority date: 2020-12-30
Filing date: 2020-12-30
Publication date: 2021-10-26
Anticipated expiration: 2030-12-30

Abstract

The utility model discloses an automatic malleation of solid-phase extraction column crosses post device, including air pump, liquid feeding pump, carousel, platform, bottom plate and frame, the up end of bottom plate is close to center department and has the frame of vertical setting through screw fixed mounting, just be provided with second step motor on the bottom plate of frame one side respectively, air pump and liquid feeding pump are fixed on the bottom plate of frame opposite side, the internally mounted of frame has first step motor, just the top of frame is rotated and is installed the spline that stretches out the frame top, and the other two sets of ports of first step motor communicate with liquid feeding pump and air pump respectively. The automatic positive pressure column passing device of the solid phase extraction column provides equipment which can automatically add liquid, automatically blow and pressurize, automatically pass the column and automatically collect eluent after passing the column, and can be widely used for sample pretreatment of target compounds in various foods, agricultural and livestock products, environmental samples and biological samples.

Description

Automatic positive-pressure column passing device for solid-phase extraction column

Technical Field

The utility model belongs to the technical field of the sample pretreatment, concretely relates to automatic malleation of solid-phase extraction post is crossed post device.

Background

A Solid Phase extraction column (abbreviated as SPE column or SPE cartridges for english Solid Phase extraction Cartridge) is a sample pretreatment device used for extraction, separation and concentration. The method is mainly applied to sample pretreatment of target compounds in various foods, agricultural and livestock products, environmental samples and biological samples.

In the use of the prior positive pressure column passing of the solid phase extraction column, the operation is basically manual, namely, a syringe is connected to the upper end of the solid phase extraction column, and liquid in the extraction column is discharged out of the extraction column by pressing the syringe. The labor is consumed, the pushing times are more, and the hands of the operators can not be consumed; along with the continuous improvement of automation, small size and delicacy required by a sample pretreatment instrument, equipment capable of automatically adding liquid and passing through a column and automatically collecting eluent after passing through the column is urgently needed.

Disclosure of Invention

An object of the utility model is to provide an automatic malleation of solid-phase extraction post is crossed post device to solve the problem that proposes in the above-mentioned background art.

In order to achieve the above object, the utility model provides a following technical scheme: an automatic positive-pressure column passing device for a solid-phase extraction column comprises an air pump, a liquid adding pump, a rotary table, a platform, a bottom plate and a frame, wherein the frame which is vertically arranged is fixedly installed at the position, close to the center, of the upper end face of the bottom plate through screws, a second stepping motor is arranged on the bottom plate on one side of the frame respectively, the air pump and the liquid adding pump are fixed on the bottom plate on the other side of the frame, a first stepping motor is installed inside the frame, a spline extending out of the upper portion of the frame is rotatably installed at the top end of the frame, and the top end of the spline is connected with a liquid blowing and adding needle through a mounting seat;

the coaxial fixedly connected with platform in top of second step motor, and open respectively in the outside on the platform has a set of outage and multiunit to place the jack, and the top of platform is equipped with the carousel, open the outside of carousel has the multiunit to be the SPE post of annular array and places the hole, wherein the upper end that the hole was placed to the SPE post is fixed with SPE post fixed block, and SPE post rubber block fixed mounting has the SPE post through the top of SPE post fixed block.

Preferably, a third stepping motor is further mounted on one side of the top end of the rack, a driven gear is fixedly sleeved outside a spline on the other side of the rack, and a driving gear connected with the driven gear through a synchronous belt in a transmission mode is mounted on a crankshaft of the third stepping motor.

Preferably, the aperture of the liquid discharge pipe is the same as that of the placement jacks, and the multiple groups of the placement jacks are arranged in an array and are inserted with eluent collection pipes.

Preferably, the blowing liquid feeding needle is positioned right above the turntable, and an electric push rod for driving the blowing liquid feeding needle to lift is arranged in a mounting seat at the top end of the blowing liquid feeding needle.

Preferably, the bottom of carousel also install with the coaxial fixed connection's of carousel rotation motor, just the SPE post passes through the joint of SPE post rubber cap and SPE post fixed block to be fixed on the carousel.

The utility model discloses a technological effect and advantage: the automatic positive-pressure solid-phase extraction column passing device changes the mode of a traditional manual push-pull injector into the mode of inserting a blowing liquid adding needle into an SPE column, and drives the blowing liquid adding needle to lift, rotate, add liquid and pressurize respectively by a first stepping motor, a third stepping motor, a liquid adding pump and an air pump, so that the whole column passing process does not need manual intervention, the column passing efficiency is greatly improved, and the labor cost is saved; simultaneously through the voltage of control air pump, thereby can control the pressure of air pump, time and the pressure of post are crossed just to control, can select different post pressure and post time of crossing to the post project of crossing of difference, reach required post effect of crossing, and the liquid feeding with blow a pipeline and a needle of sharing, the cost is reduced, the instrument space has been practiced thrift, SPE post passes through SPE post rubber cap rotary joint on SPE post fixed block in addition, still made things convenient for the installation of SPE post to place and guaranteed can not take the SPE post when the SPE post rubber cap is extracted to the liquid feeding needle of blowing.

Drawings

Fig. 1 is a schematic structural view of the present invention;

fig. 2 is a left side view of the present invention;

fig. 3 is a right side view of the present invention;

fig. 4 is a top view of the present invention;

fig. 5 is the utility model discloses a SPE post fixed block and SPE post structural schematic.

In the figure: 1. an air pump; 2. a first stepper motor; 3. a liquid adding pump; 4. a spline; 5. a gas blowing liquid adding needle; 6. SPE column fixing block; 7. SPE column rubber cap; 8. SPE column; 9. a turntable; 10. a drain hole; 11. a second stepping motor; 12. placing the jacks; 13. a platform; 14. SPE column placing holes; 15. a third step motor; 16. a driven gear; 17. a base plate; 18. an eluent collecting pipe; 19. and a frame.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.

The utility model provides an automatic malleation of solid-phase extraction post crosses post device as shown in fig. 1-5, including air pump 1, liquid feeding pump 3, carousel 9, platform 13, bottom plate 17 and frame 19, the up end of bottom plate 17 is close to center department and installs frame 19 of vertical setting through screw fixed mounting, just be provided with second step motor 11 on the bottom plate 17 of frame 19 one side respectively, air pump 1 and liquid feeding pump 3 are fixed on the bottom plate 17 of frame 19 opposite side, the internally mounted of frame 19 has first step motor 2, and the top of frame 19 rotates and installs the spline 4 that stretches out above frame 19, and first step motor 2 drives spline 4 and goes up the lift removal on frame 19 top, wherein the top of spline 4 is connected with through the mount pad and blows and adds liquid needle 5;

the coaxial fixedly connected with platform 13 in top of second step motor 11, platform 13 are discoid, and the outside on the platform 13 is opened respectively has a set of outage 10 and multiunit to place jack 12, and the top of platform 13 is equipped with carousel 9, the outside of carousel 9 is opened the SPE post that has the multiunit to be the annular array and is placed hole 14, wherein the upper end that the hole 14 was placed to the SPE post is fixed with SPE post fixed block 6, and SPE post fixed mounting has SPE post 8 through SPE post rubber cap 7 fixed mounting on the top of SPE post fixed block 6, and here only need rotate 90 after in the SPE post 8 patchhole when using, can be with the cap edge card of cap go into the draw-in groove, the purpose is that can not take SPE post 8 when SPE air blowing needle 5 extracts SPE post rubber cap 7.

Specifically, a third stepping motor 15 is further installed on one side of the top end of the rack 19, a driven gear 16 is fixedly sleeved outside the spline 4 on the other side, and a driving gear connected with the driven gear 16 through a synchronous belt is installed on a shaft of the third stepping motor 15, so that the third stepping motor 15 can rotate to drive the spline 4 to rotate, and the installation seat drives the liquid adding blowing needle 5 to rotate.

Specifically, the aperture of the drain pipe is the same as that of the placement jacks 12, multiple groups of the placement jacks 12 are arranged in an array mode, the eluent collection pipe 18 is inserted into the multiple groups of the placement jacks 12, and the platform 13 for placing the eluent collection pipe 18 can freely select liquid needing to be collected or liquid needing not to be collected.

Specifically, the air blowing liquid adding needle 5 is located right above the turntable 9, and the air blowing liquid adding needle 5 rotates, lifts and rotates on the rack 19 through the spline 4 by the first stepping motor 2 and the third stepping motor 15 respectively.

Specifically, the bottom of carousel 9 also installs the rotation motor with carousel 9 coaxial fixed connection (refer to the design of platform 13 here, although not showing concrete connection in the figure, in the time of the in-service use, must carry out the installation of carousel 9 through rotating the motor), and SPE post 8 is fixed on carousel 9 through the joint of SPE post rubber cap 7 with SPE post fixed block 6.

The working principle is that the working process of the automatic positive-pressure column passing device of the solid-phase extraction column comprises the following steps:

1. a rubber cap is plugged into the 8 column ports of the SPE column;

2. the SPE column 8 is inserted into the SPE column placing hole 14 of the turntable 9 and then rotated by 90 degrees, so that a cap (here, a SPE column rubber cap) of the SPE column is clamped into the clamping groove along the edge, and a plurality of SPE columns 8 can be inserted at one time;

3. the first stepping motor 2 is switched to the liquid adding pump 3;

4. the air blowing liquid adding needle 5 sucks liquid which needs to pass through the column through the liquid adding pump 3;

5. the air blowing liquid adding needle 5 moves to the upper part of the SPE column 8;

6. a blowing liquid adding needle 5 is inserted into a rubber cap hole of the 8-port SPE column to add liquid required to pass through the column;

7. the first stepping motor 2 is switched to the air pump 1, the air pump 1 is started, and the air blowing liquid adding needle 5 starts to apply positive pressure to the SPE column 8;

8. if the liquid passing through the column does not need to be collected, the platform 13 for placing the eluent collecting pipe 18 rotates the liquid discharging hole 10 to the lower part of the SPE column 8, so that the waste liquid is dripped and flows away; if the liquid passing through the column needs to be collected, the platform 13 for placing the eluent collecting pipe 18 rotates the placing jack 12 for placing the eluent collecting pipe 18 to the lower part of the SPE column 8, so that the eluent needing to be collected is dripped into the eluent collecting pipe 18;

7. and (6) ending.

Finally, it should be noted that: although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that modifications and variations can be made in the embodiments or in part of the technical features of the embodiments without departing from the spirit and the scope of the invention.

Claims

1. The utility model provides an automatic positive pressure column passing device of solid phase extraction column, includes air pump (1), liquid feeding pump (3), carousel (9), platform (13), bottom plate (17) and frame (19), its characterized in that: a vertically arranged rack (19) is fixedly installed on the upper end face of the bottom plate (17) close to the center through screws, a second stepping motor (11) is arranged on the bottom plate (17) on one side of the rack (19) respectively, the air pump (1) and the liquid feeding pump (3) are fixed on the bottom plate (17) on the other side of the rack (19), a first stepping motor (2) is installed inside the rack (19), a spline (4) extending out of the upper portion of the rack (19) is rotatably installed at the top end of the rack (19), and the top end of the spline (4) is connected with a blowing liquid feeding needle (5) through a mounting seat;

the coaxial fixedly connected with platform (13) in top of second step motor (11), and the outside on platform (13) is opened respectively has a set of outage (10) and multiunit to place jack (12), and the top of platform (13) is equipped with carousel (9), the outside of carousel (9) is opened the SPE post that has the multiunit to be the annular array and is placed hole (14), wherein the upper end that the SPE post was placed hole (14) is fixed with SPE post fixed block (6), and SPE post rubber cap (7) fixed mounting is passed through on the top of SPE post fixed block (6) has SPE post (8).

2. The automatic positive pressure column passing device of the solid phase extraction column according to claim 1, wherein: a third stepping motor (15) is further installed on one side of the top end of the rack (19), a driven gear (16) is fixedly sleeved outside the spline (4) on the other side, and a driving gear connected with the driven gear (16) through a synchronous belt in a transmission mode is installed on a crankshaft of the third stepping motor (15).

3. The automatic positive pressure column passing device of the solid phase extraction column according to claim 1, wherein: the aperture of the liquid discharge pipe is the same as that of the placement jacks (12), and a plurality of groups of the placement jacks (12) are arranged in an array and are inserted with eluent collecting pipes (18).

4. The automatic positive pressure column passing device of the solid phase extraction column according to claim 1, wherein: the air blowing liquid adding needle (5) is positioned right above the turntable (9), and an electric push rod for driving the air blowing liquid adding needle (5) to lift is arranged in a mounting seat at the top end of the air blowing liquid adding needle (5).

5. The automatic positive pressure column passing device of the solid phase extraction column according to claim 1, wherein: the bottom of carousel (9) also install the rotation motor with the coaxial fixed connection of carousel (9), just SPE post (8) are fixed on carousel (9) through the joint of SPE post rubber cap (7) with SPE post fixed block (6).