CN215263548U - Detection bottle capable of simultaneously detecting multiple markers - Google Patents

Detection bottle capable of simultaneously detecting multiple markers Download PDF

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Publication number
CN215263548U
CN215263548U CN202120881607.0U CN202120881607U CN215263548U CN 215263548 U CN215263548 U CN 215263548U CN 202120881607 U CN202120881607 U CN 202120881607U CN 215263548 U CN215263548 U CN 215263548U
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detection
bottle body
strip
sampling
space
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CN202120881607.0U
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Chinese (zh)
Inventor
王战争
刘晓磊
张慧丽
张会刚
张彩霞
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Zhengzhou Saitukang Biotechnology Co ltd
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Zhengzhou Saitukang Biotechnology Co ltd
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Abstract

The utility model relates to a detection bottle capable of detecting multiple markers simultaneously, which comprises a transparent detection bottle body and a sample liquid cover detachably connected at the bottleneck of the detection bottle body, the interior of the bottle body is divided into a plurality of independent detection spaces by a clapboard, each detection space is internally provided with a detection strip, the specific antigen section of the detection strip in each detection space is different specific antigens, the sample liquid cover comprises a sampling part and a connecting part, the connecting part is in threaded connection with the bottleneck of the detection bottle body, the bottom end of the sampling part is provided with a liquid separating plate capable of covering the bottleneck of the detection bottle body, the liquid separating plate is provided with a plurality of liquid inlet holes, the liquid inlet holes are correspondingly communicated with the detection spaces, the sampling part is in a convex shape, the middle part of the top end of the sampling part is provided with a straw through hole, the sampling straw is inserted in the sample liquid cover through the straw through hole, and the outer surface of each detection space is provided with a colorimetric card, thus, the detection bottle has a simple structure, easy operation, high detection efficiency, low cost and convenient popularization and application in primary hospitals.

Description

Detection bottle capable of simultaneously detecting multiple markers
Technical Field
The utility model relates to the technical field of medical equipment, more specifically say, relate to a can detect detection bottle of multiple marker simultaneously.
Background
At present, the number of cancer patients in China is gradually increased, the life health of human beings is seriously threatened, a heavy burden is also caused to the society and family houses, the early detection, the early diagnosis and the early treatment of the cancer are one of the most important ways for improving the cure rate of the cancer and the five-year survival rate and reducing the death rate, and the detection of various tumor marker indexes in blood is the most effective method for early screening the cancer, so that various malignant tumors can be timely found. However, the existing detection instrument can only detect the change of a single tumor marker once, and the change data of the single tumor marker is thinner as the basis for early diagnosis of the tumor; in addition, the detection instrument used for detecting the tumor marker is mostly a large instrument with complex operation, the detection cost is increased invisibly, and the popularization and the application in primary hospitals are not convenient.
Therefore, how to solve the above problems becomes an important technical problem to be solved by those skilled in the art.
SUMMERY OF THE UTILITY MODEL
The utility model provides a can detect detection bottle of multiple marker simultaneously to solve present detecting instrument and can only once detect to the change of single tumour marker, be used as the detecting instrument who detects the tumour marker in addition, the large-scale instrument that is mostly complicated for the operation has also increased the detection cost among the intangible, is not convenient for basic unit's hospital and uses widely.
The utility model discloses a can detect detection bottle of multiple tumor marker simultaneously adopts following technical scheme:
a detection bottle capable of detecting multiple markers simultaneously, which comprises a transparent detection bottle body and a sample liquid cover detachably connected with the mouth of the detection bottle body, a plurality of clapboards are radially arranged in the detection bottle body and extend along the axial direction, each clapboard separates the detection bottle body into mutually independent detection spaces, the sample liquid cover comprises a sampling part and a connecting part, the connecting part is in threaded connection with the bottle mouth of the detection bottle body, the bottom end of the sampling part is provided with a liquid separating plate which can cover the bottle mouth of the detection bottle body, the liquid separating plate is provided with a plurality of liquid inlet holes, the liquid inlet hole is correspondingly communicated with the detection spaces, each detection space is internally provided with a detection strip, the detection strip comprises a water absorption filter paper section, a cellulose nitrate section and a specific antigen section, wherein the water absorption filter paper section, the cellulose nitrate section and the specific antigen section are sequentially arranged in the detection space from top to bottom and are integrally formed; the water absorption filter paper segment is positioned at the port of the detection space and is adjacent to the liquid inlet hole, the specific antigen segments in each detection space are different types of specific antigens, two axially extending fixing columns for fixing the detection strip are arranged on the inner wall of each detection space, the two fixing columns are opposite and arranged at intervals, the fixing columns are provided with axially extending clamping rails, clamping strips are arranged on two sides of the detection strip and are slidably clamped in the clamping rails, a colorimetric card is arranged on the outer surface of each detection space, the colorimetric card is arranged adjacent to the detection strip, the sampling part is in a shape like a Chinese character 'tu', a straw through hole is formed in the middle of the top end of the sampling part, and the sampling straw is inserted in the sample liquid cover through the straw through hole.
Preferably, the card strip and the detection strip are of an integrated structure.
Preferably, the cross section of the fixing column is concave, and the fixing column is adhered to the inner wall of the detection space.
Preferably, the outer surface of the sampling straw is provided with a scale.
The utility model has the advantages that: a can detect the detection bottle of many markers at the same time, the transparent bottle is internal to separate into many independent detection spaces through the baffle, every detection space has detection strips, the specificity antigen end of detection strip in every space is all different, therefore every detection strip in detection space can detect a tumor marker independently, can detect many tumor markers at the same time through this detection bottle, and detection strip and fixed column slip joint in the card rail through the card strip, before detecting, confirm the tumor marker to be detected, then clamp the detection strip with corresponding specificity antigen in the card rail, can adjust the corresponding detection strip of replacement rationally according to the tumor marker to be detected, many detection strips to detect different tumor markers are combined freely in the same bottle, obtain the necessary testing result, convenient and fast, will not cause the wasting of resources, and this detection bottle simple structure, easy to operate, the cost is lower, and the sample straw is pegged graft in sample liquid lid through the straw through-hole at sampling portion top middle part, is difficult for being contaminated, influences the testing result, and takes the convenience, and every detection space's surface all is equipped with the colour comparison card, and the colour comparison card is adjacent with the test strip, and the testing result is direct to be compared with the colour comparison card, and the testing result observation is conveniently observed.
It is to be understood that both the foregoing general description and the following detailed description are exemplary and explanatory only and are not restrictive of the application.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings needed to be used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to these drawings without inventive exercise.
The accompanying drawings, which are incorporated in and constitute a part of this specification, illustrate embodiments consistent with the present application and together with the description, serve to explain the principles of the application.
FIG. 1 is a schematic structural view of a detection bottle according to an embodiment of the present invention;
FIG. 2 is a top view of a bottle mouth of a detection bottle in an embodiment of the present invention;
FIG. 3 is a schematic structural view of a liquid separation plate according to an embodiment of the present invention;
FIG. 4 is a schematic structural view of a detection strip according to an embodiment of the present invention;
fig. 5 is a schematic structural view of a fixing column in an embodiment of the present invention.
In the figure:
1-detection bottle body, 2-partition board, 3-detection space, 4-sampling part, 5-connecting part, 6-liquid separation board, 7-liquid inlet hole, 8-detection strip, 9-water absorption filter paper segment, 10-nitrocellulose segment, 11-specific antigen segment, 12-fixing column, 13-clamping rail, 14-clamping strip, 15-colorimetric card and 16-sampling suction pipe.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
Hereinafter, embodiments will be described with reference to the drawings. The embodiments described below do not limit the scope of the invention described in the claims. Further, the entire contents of the configurations shown in the following embodiments are not limited to those necessary as a solution of the invention described in the claims.
Referring to fig. 1-5, the present embodiment provides a detection bottle capable of detecting multiple markers simultaneously, including a transparent detection bottle body 1 and a sample liquid cap detachably connected to a mouth of the detection bottle body 1, wherein the transparent material of the bottle body is easy to observe the detection result, a plurality of partition plates 2 are radially disposed in the detection bottle body 1, the partition plates 2 extend along the axial direction, each partition plate 2 separates the detection bottle body 1 into mutually independent detection spaces 3, specifically, as shown in fig. 2, the present embodiment can be separated into four detection spaces, and the number of the detection spaces 3 can be other values, depending on the circumstances.
In this embodiment, as shown in fig. 1, the sample liquid cover includes a sampling portion 4 and a connecting portion 5, the connecting portion 5 is in threaded connection with the bottle mouth of the detection bottle body 1, specifically, the connecting portion 5 is provided with an internal thread, the outer surface of the bottle mouth of the detection bottle body 1 is provided with an external thread, the internal thread is fixedly connected with the external thread, the bottom end of the sampling portion 4 is provided with a liquid separation plate 6 capable of covering the bottle mouth of the detection bottle body 1, the liquid separation plate 6 is provided with a plurality of liquid inlet holes 7, the liquid inlet holes 7 are correspondingly communicated with the detection spaces 3, each detection space 3 is provided with a detection strip 8, as shown in fig. 4, the detection strip 8 includes a water-absorbing filter paper segment 9, a nitrocellulose segment 10 and a specific antigen segment 11, and the water-absorbing filter paper segment 9, the nitrocellulose segment 10 and the specific antigen segment 11 are sequentially arranged from top to bottom in the detection space 3 and integrally formed; wherein the water absorption filter paper segment 9 is positioned at the port of the detection space 3 and is adjacent to the liquid inlet hole 7, and the specific antigen segment 11 in each detection space 3 is different specific antigens, so that the detection strip 8 in each detection space 3 can independently detect one tumor marker, and a plurality of tumor markers can be detected simultaneously by the detection bottle.
Wherein, as shown in fig. 2, each inner wall of the detection space 3 is provided with two axially extending fixing columns 12 for fixing the detection strip 8, the two fixing columns 12 are opposite and arranged at intervals, as shown in fig. 5, the fixing columns 12 are provided with axially extending clamping rails 13, as shown in fig. 4, the clamping strips 14 are arranged on two sides of the detection strip 8, the clamping strips 14 are slidably clamped in the clamping rails 13, before detection, the tumor marker to be detected is determined, then the detection strip 8 with the corresponding specific antigen is clamped in the clamping rails 13, the corresponding detection strip can be reasonably adjusted and replaced according to the tumor marker to be detected, and the multiple detection strips for detecting different tumor markers are freely combined in the same bottle body, so as to obtain the required detection result, and the detection is convenient and rapid, and no resource waste is caused.
It should be noted that, 3 surfaces in every detection space all are equipped with colour comparison card 15, and colour comparison card 15 sets up with test strip 8 is adjacent, and convenient contrast testing result reaches the purpose of detection according to the colour development of specificity antigen section 11, and the colour development of test strip 8 is compared with adjacent colour comparison card 15, and the testing result is observed conveniently to be observed, is learnt fast, has improved detection efficiency.
Further, as shown in fig. 1, the sampling portion 4 in this embodiment is in a shape of a "convex", a straw through hole is formed in the middle of the top end of the sampling portion 4, and the sampling straw 16 is inserted into the sample liquid cover through the straw through hole, so that the sampling straw is not easily polluted, the detection result is prevented from being affected, and the sampling straw is convenient to take. Furthermore, in order to facilitate the sampling of the medical staff, the outer surface of the sampling suction tube 16 is provided with scales.
So set up, this detection bottle simple structure, easy to operate, the cost is lower, has solved present detecting instrument and can only once detect to the change of single tumour marker, is used as the detecting instrument who detects the tumour marker in addition, and the large-scale instrument that is mostly complicated for the operation has also increased the detection cost among the intangible, the problem of the popularization and application of primary hospital of being not convenient for.
In the preferred scheme of this embodiment, card strip and test strip formula structure as an organic whole, so, simplified processing technology, labour saving and time saving.
Preferably, the cross-sectional shape of the fixing column 12 is concave, and the fixing column 12 is bonded on the inner wall of the detection space 3, so that the fixing is convenient and fast.
In the following embodiments, the above-mentioned various devices or components in the above-mentioned embodiments are combined, and the overall structure of the detection bottle is illustrated, by adopting the above structure, after a blood sample is drawn from a subject, the blood sample is diluted, the sampling suction tube 16 is detached to be sampled, and then the sample is sampled to the sample liquid cover, the water absorption filter paper section 9 in the detection strip 8 absorbs the blood sample specimen to diffuse to the nitrocellulose section 10, the nitrocellulose section 10 uses a microporous filter membrane as a carrier, coats colloidal gold and known antibodies, after the blood sample specimen is infiltrated, the blood sample specimen is combined with the colloidal gold and the antibodies, and diffuses to the specific antigen section 11 through the capillary action of the filter membrane, and the specific antigen section 11 also uses the microporous filter membrane as a carrier, coats the antigen of the detected tumor marker, so that the blood sample after being combined with the colloidal gold and the antibodies diffuses to the specific antigen section 11 to be combined with the antigen for color development, thereby achieving the purpose of detection. However, the specific antigen segment 11 in each detection space is different types of specific antigens, and can be freely combined and placed into the corresponding detection strip 8 according to the tumor markers to be detected in actual needs, and a plurality of detection spaces 3, for example, the specific antigen segment 11 in one detection space 3 is coated with alpha fetoprotein antigen which is used for detecting liver tumor markers and can be used for investigating primary hepatocellular carcinoma; the specific antigen segment 11 in the detection space 3 of the second detection space is coated with neuron specific enolase which is used for detecting small cell lung cancer and neuroblast tumor markers and can screen early small cell cancer, renal neuroblastoma, neuroendocrine cell tumor and the like; and a carcinoembryonic antigen is coated on the specific antigen segment 11 in the detection space 3, is used for detecting tumor markers of stomach, broad spectrum, intestinal tract, rectum, pancreas, gallbladder and the like, and can screen early gastric cancer, rectal cancer, colon cancer, lung cancer, pancreatic cancer, breast cancer and the like. Because there are a plurality of detection spaces, the antigen coated by the specific antigen segment in the rest detection spaces can also be antigen for detecting tumor markers such as cytokeratin, cancer antigen (CA-15-3) and the like.
It should be noted that "up" and "down" described herein refer to the detection bottle when it is in the state of being placed as shown in fig. 1, and "axial" refers to the direction of the central axis of rotation of the cylinder, i.e. the direction common to the central axis, in general for the cylindrical object.
The above description is only a preferred embodiment of the present invention, and should not be taken as limiting the invention, and any modifications, equivalent replacements, improvements, etc. made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
It is understood that the same or similar parts in the above embodiments may be mutually referred to, and the same or similar parts in other embodiments may be referred to for the content which is not described in detail in some embodiments.
The previous description of the disclosed embodiments is provided to enable any person skilled in the art to make or use the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the invention. Thus, the present invention is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.

Claims (4)

1. A detection bottle capable of detecting multiple markers simultaneously is characterized by comprising a transparent detection bottle body and a sample liquid cover detachably connected with the mouth of the detection bottle body, a plurality of clapboards are radially arranged in the detection bottle body and extend along the axial direction, each clapboard separates the detection bottle body into mutually independent detection spaces, the sample liquid cover comprises a sampling part and a connecting part, the connecting part is in threaded connection with the bottle mouth of the detection bottle body, the bottom end of the sampling part is provided with a liquid separating plate which can cover the bottle mouth of the detection bottle body, the liquid separating plate is provided with a plurality of liquid inlet holes, the liquid inlet hole is correspondingly communicated with the detection spaces, each detection space is internally provided with a detection strip, the detection strip comprises a water absorption filter paper section, a cellulose nitrate section and a specific antigen section, wherein the water absorption filter paper section, the cellulose nitrate section and the specific antigen section are sequentially arranged in the detection space from top to bottom and are integrally formed; the water absorption filter paper segment is positioned at a port of the detection space and is adjacent to the liquid inlet hole, the specific antigen segments in each detection space are different types of specific antigens, two axially extending fixing columns for fixing the detection strip are arranged on the inner wall of each detection space, the two fixing columns are opposite and arranged at intervals, the fixing columns are provided with axially extending clamping rails, clamping strips are arranged on two sides of the detection strip and are slidably clamped in the clamping rails, a colorimetric card is arranged on the outer surface of each detection space, the colorimetric card is arranged adjacent to the detection strip, the sampling part is in a shape like a Chinese character 'tu', a straw through hole is formed in the middle of the top end of the sampling part, and a sampling straw is inserted in the sample liquid cover through the straw through hole.
2. The vial according to claim 1, wherein the card strip and the test strip are of one-piece construction.
3. The detecting bottle capable of detecting multiple markers simultaneously as claimed in claim 1, wherein the cross-sectional shape of the fixing post is a concave shape, and the fixing post is adhered to the inner wall of the detecting space.
4. The detection bottle capable of detecting multiple markers simultaneously as claimed in claim 1, wherein the sampling pipette has a scale on its outer surface.
CN202120881607.0U 2021-04-27 2021-04-27 Detection bottle capable of simultaneously detecting multiple markers Active CN215263548U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202120881607.0U CN215263548U (en) 2021-04-27 2021-04-27 Detection bottle capable of simultaneously detecting multiple markers

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202120881607.0U CN215263548U (en) 2021-04-27 2021-04-27 Detection bottle capable of simultaneously detecting multiple markers

Publications (1)

Publication Number Publication Date
CN215263548U true CN215263548U (en) 2021-12-21

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN202120881607.0U Active CN215263548U (en) 2021-04-27 2021-04-27 Detection bottle capable of simultaneously detecting multiple markers

Country Status (1)

Country Link
CN (1) CN215263548U (en)

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