CN215162747U - Rapid detection and treatment device for pathogenic microorganisms - Google Patents

Rapid detection and treatment device for pathogenic microorganisms Download PDF

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Publication number
CN215162747U
CN215162747U CN202121166348.XU CN202121166348U CN215162747U CN 215162747 U CN215162747 U CN 215162747U CN 202121166348 U CN202121166348 U CN 202121166348U CN 215162747 U CN215162747 U CN 215162747U
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China
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detection
sample
liquid
upper computer
move
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CN202121166348.XU
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Chinese (zh)
Inventor
常宇桐
胡孔新
马雪征
张丽萍
李凡双
牛羽
李慧鹏
陈雪
王贝贝
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Hangzhou Enrichment Biotechnology Co ltd
Chinese Academy of Inspection and Quarantine CAIQ
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Hangzhou Enrichment Biotechnology Co ltd
Chinese Academy of Inspection and Quarantine CAIQ
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Abstract

The utility model relates to a pathogenic microorganism short-term test processing apparatus, it includes: the liquid transferring device comprises a main box, a liquid transferring mechanism, a detection mechanism and an upper computer control mechanism, wherein the liquid transferring mechanism and the detection mechanism are arranged in the main box, and the upper computer control mechanism is arranged at the top end of the outer part of the main box. The utility model can be used for detecting novel coronavirus, the whole process of nucleic acid extraction and detection can be completed within 30 minutes, the detection time is greatly shortened, the detection efficiency is improved, and the labor cost and the time cost are effectively reduced; the RPA reaction can be carried out at normal temperature, the requirement on the instrument is low, the field and automation of detection can be realized by utilizing the set of device, and a new idea is provided for the detection of novel coronavirus nucleic acid.

Description

Rapid detection and treatment device for pathogenic microorganisms
Technical Field
The utility model relates to a pathogenic microorganism short-term test processing apparatus belongs to check out test set technical field.
Background
In the traditional nucleic acid detection method, the time consumption is long, the steps are complicated, professional laboratory personnel are required for detection, the detection flow is complex, all links are relatively independent, and different rooms are frequently required to be replaced for sample adding, loading and the like. The time from sample collection to detection completion is long, so that the conditions of time difference or long-distance transportation and the like between collection and detection ring sections can not be realized, real-time detection can not be realized, and automation and field can not be realized.
Disclosure of Invention
Technical problem to be solved
In order to solve the above problems in the prior art, the utility model provides a quick detection and processing device for pathogenic microorganisms.
(II) technical scheme
In order to achieve the above object, the utility model discloses a main technical scheme include:
a rapid pathogenic microorganism detection processing apparatus comprises: main part case, move liquid mechanism, detection mechanism and upper computer control mechanism, move liquid mechanism and detection mechanism and locate the main part incasement, upper computer control mechanism locates the outside top of main part case, wherein: move liquid mechanism and be used for the transfer of liquid, the application of sample, move liquid mechanism and include: the controller controls the mechanical arm to transfer the sample and the required liquid to the detection mechanism according to the control information; the detection mechanism is used for detecting the sample and generating a detection result; the detection mechanism comprises a second communication interface, a detection module and a temperature control module, wherein the second communication interface is in communication connection with the integrated network interface and receives a detection control signal; the second communication interface is connected with and controls the detection module and the temperature control module; the upper computer control mechanism is connected with the integrated network interface, and sends control signals to the liquid-transferring mechanism and the detection mechanism through the integrated network interface and receives detection results.
In the apparatus for rapidly detecting and processing pathogenic microorganisms, preferably, the detection module is an RT-PCR instrument and is disposed below the inside of the main box.
According to the above apparatus for rapidly detecting and processing pathogenic microorganisms, preferably, the mechanical arm is disposed above the interior of the main box, and the mechanical arm is provided with a mounting column for a pipette head for aspirating, and the mounting column is disposed corresponding to the position of the reaction tube in the sample rack.
According to the rapid detection processing device for pathogenic microorganisms, preferably, the temperature control module is used for controlling the reaction temperature, and a gun head placing frame and a sample shelf are further arranged on the left side of the detection module in the main box; the mechanical arm can move to the gun head placing frame to replace the gun head and can also move to the sample shelf to adsorb sample solution.
The utility model provides a quick detection and processing device of pathogenic microorganism, preferably, main part bottom of the case portion is equipped with four universal wheels, is convenient for the removal of device.
The utility model provides a quick detection and processing apparatus of pathogenic microorganism, preferably, the rear portion of main part case is equipped with a plurality of louvres for the instrument heat dissipation.
The device for rapidly detecting and processing the pathogenic microorganisms is characterized in that a front door of the main body box is preferably a perspective door, so that the operation process of the device can be observed conveniently.
(III) advantageous effects
The utility model has the advantages that:
the utility model provides a quick detection and processing device of pathogenic microorganism can be used for detecting novel coronavirus, can finish the whole process of nucleic acid extraction and detection within 30 minutes, greatly shortens the detection time, improves the detection efficiency, and effectively reduces the labor cost and the time cost; the RPA reaction can be carried out at normal temperature, the requirement on the instrument is low, the field and automation of detection can be realized by utilizing the set of device, and a new idea is provided for the detection of novel coronavirus nucleic acid.
Drawings
FIG. 1 is a schematic diagram of the internal structure of a rapid pathogenic microorganism detection and treatment device;
FIG. 2 is a perspective view of the rapid pathogenic microorganism detection and treatment apparatus.
[ description of reference ]
1: a main body case;
2: a pipetting mechanism;
3: a detection mechanism;
4: an upper computer control mechanism;
5: a detection module;
6: a temperature control module;
7: a gun head placing frame;
8: a sample holder;
9: a universal wheel;
10: and (4) heat dissipation holes.
Detailed Description
For a better understanding of the present invention, reference will now be made in detail to the present invention, examples of which are illustrated in the accompanying drawings.
Example 1
A rapid pathogenic microorganism detection processing apparatus, as shown in fig. 1, comprising: the liquid transferring device comprises a main body box 1, a liquid transferring mechanism 2, a detection mechanism 3 and an upper computer control mechanism 4, wherein the liquid transferring mechanism 2 and the detection mechanism 3 are arranged in the main body box 1, and the upper computer control mechanism 4 is arranged at the top end of the outer part of the main body box 1. Move liquid mechanism and be used for the transfer of liquid, the application of sample, move liquid mechanism 1 and include: the first communication interface, the controller and the mechanical arm are in communication connection with the integrated network interface through the first communication interface to obtain pipetting control information, and the controller controls the mechanical arm to transfer the sample and the required liquid to the detection mechanism 2 according to the control information; the detection mechanism 2 is used for detecting the sample and generating a detection result; the detection mechanism 2 comprises a second communication interface, a detection module and a temperature control module, wherein the second communication interface is in communication connection with the integrated network interface and receives a detection control signal; the second communication interface is connected with and controls the detection module 5 and the temperature control module 6; the upper computer control mechanism 4 is connected with the integrated network interface, and sends control signals to the liquid-transferring mechanism 2 and the detection mechanism 3 through the integrated network interface and receives detection results. The detection module 5 can be an RT-PCR instrument and is arranged below the inside of the main body box 1.
The arm is located main part 1 inside top, is equipped with the erection column that is used for the rifle head of imbibition on the arm, and the position of reaction tube corresponds the setting in erection column and the sample shelf, and the erection column has 96 and corresponds the range with 96 orifice plates. The temperature control module is used for controlling the temperature of the reaction, can be arranged on the left side of the interior of the main body box, and is also provided with a gun head placing frame 7 and a sample shelf 8, and the interior of the main body box 1 is arranged on the left side of the detection module; the mechanical arm can move to the gun head placing frame 7 to replace the gun head, and can also move to the sample shelf 8 to adsorb the sample solution.
In order to facilitate the movement of the device, four universal wheels 9 are arranged at the bottom of the main body box as shown in fig. 2. The front door of the main body box is set as a perspective door, so that the whole operation process of the device can be observed conveniently. The rear part of the main body case 1 is provided with a plurality of heat dissipation holes 10 for heat dissipation of instruments.
The device can be used for detecting novel coronavirus or other pathogenic microorganisms, and the method for detecting the novel coronavirus comprises the following steps:
(1) placing the prepared trace nucleic acid releasing agent on a sample shelf;
(2) mixing the trace nucleic acid releasing agent with the sample by using an upper computer control mechanism and a liquid transfer mechanism;
(3) carrying out recombinase polymerase amplification reaction on the RT-RPA kit added with the sample, a primer and a probe for detecting the novel coronavirus by using a temperature control module;
(4) collect FAM detection channel fluorescence signal through detection module to the fluorescence signal that will collect sends host computer control mechanism through second communication interface and obtains the testing result, utilizes this utility model's pathogenic microorganism short-term test processing apparatus to realize the application of sample, the automation mechanized operation of operating the computer.

Claims (7)

1. A pathogenic microorganism rapid detection processing apparatus is characterized in that it includes: main part case, move liquid mechanism, detection mechanism and upper computer control mechanism, move liquid mechanism and detection mechanism and locate the main part incasement, upper computer control mechanism locates the outside top of main part case, wherein: move liquid mechanism and be used for the transfer of liquid, the application of sample, move liquid mechanism and include: the controller controls the mechanical arm to transfer the sample and the required liquid to the detection mechanism according to the control information; the detection mechanism is used for detecting the sample and generating a detection result; the detection mechanism comprises a second communication interface, a detection module and a temperature control module, wherein the second communication interface is in communication connection with the integrated network interface and receives a detection control signal; the second communication interface is connected with and controls the detection module and the temperature control module; the upper computer control mechanism is connected with the integrated network interface, and sends control signals to the liquid-transferring mechanism and the detection mechanism through the integrated network interface and receives detection results.
2. The apparatus of claim 1, wherein the detection module is an RT-PCR instrument and is disposed below the main box.
3. The apparatus according to claim 1, wherein the robotic arm is disposed above the interior of the main box, and the robotic arm is provided with a mounting post for a pipette tip for pipetting, the mounting post corresponding to the position of the reaction tube in the sample rack.
4. The rapid pathogenic microorganism detection processing apparatus according to claim 1, wherein the temperature control module is configured to control the reaction temperature, and a gun head placing rack and a sample rack are further disposed on the left side of the detection module inside the main box; the mechanical arm can move to the gun head placing frame to replace the gun head and can also move to the sample shelf to adsorb sample solution.
5. The apparatus for rapidly detecting and processing pathogenic microorganisms according to claim 1, wherein four universal wheels are provided at the bottom of the main body case to facilitate the movement of the apparatus.
6. The apparatus of claim 1, wherein the main body case has a plurality of heat dissipation holes at the rear thereof for dissipating heat from the instrument.
7. The apparatus for rapidly detecting and processing pathogenic microorganisms according to claim 1, wherein a front door of the main body box is a see-through door for facilitating observation of the operation process of the apparatus.
CN202121166348.XU 2021-05-28 2021-05-28 Rapid detection and treatment device for pathogenic microorganisms Active CN215162747U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202121166348.XU CN215162747U (en) 2021-05-28 2021-05-28 Rapid detection and treatment device for pathogenic microorganisms

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202121166348.XU CN215162747U (en) 2021-05-28 2021-05-28 Rapid detection and treatment device for pathogenic microorganisms

Publications (1)

Publication Number Publication Date
CN215162747U true CN215162747U (en) 2021-12-14

Family

ID=79373092

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202121166348.XU Active CN215162747U (en) 2021-05-28 2021-05-28 Rapid detection and treatment device for pathogenic microorganisms

Country Status (1)

Country Link
CN (1) CN215162747U (en)

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