CN215103311U - Centrifugal separation case is used in immune cell separation - Google Patents
Centrifugal separation case is used in immune cell separation Download PDFInfo
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- CN215103311U CN215103311U CN202121519757.3U CN202121519757U CN215103311U CN 215103311 U CN215103311 U CN 215103311U CN 202121519757 U CN202121519757 U CN 202121519757U CN 215103311 U CN215103311 U CN 215103311U
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Abstract
The utility model provides a centrifugal separation case is used in immune cell separation, including the separator box, the separator box is including separating mechanism, separating mechanism is including separator cabin and stock solution cabin, the bottom of separator cabin is equipped with the magnetic bead box, the interior diapire of magnetic bead box is equipped with a plurality of magnetic bead, the bottom of magnetic bead box is equipped with the electro-magnet, the surface equipartition of separator cabin is equipped with a plurality of outage 0, the bottom of electro-magnet is through first pivot and separator box swing joint, the surface of first pivot is equipped with bearing and worm wheel, the outer loop and the stock solution cabin of bearing are connected, the separator box is including worm and second pivot, the worm is connected with worm wheel drive, the one end of worm runs through the separator box and is equipped with the motor, the surface of worm is equipped with first drive wheel. The utility model discloses a separation effect of preferred can discharge the waste liquid fast to can conveniently come the temperature in the adjusting device according to the speed of separation, satisfied the practicality of device.
Description
Technical Field
The utility model mainly relates to the technical field of centrifugal separation boxes, in particular to a centrifugal separation box for separating immune cells.
Background
A centrifugal separator is a machine that separates components from a liquid and solid particles or a mixture of a liquid and a liquid by using centrifugal force, and is also called a tube centrifuge. The centrifugal separator is mainly used for separating solid particles from liquid in suspension, wherein, in the research of immune cells, the immune cells need to be separated from a mixed cell population, so a centrifugal separation box for separating the immune cells is needed.
For example, the utility model of CN201620580226.8, comprises an outer casing, a supporting leg, a centrifugal rotating device and a centrifugal chamber, wherein a case cover is arranged on the top surface of the right side of the outer casing, a control panel is arranged on the left side surface of the outer casing, a display screen, an adjusting knob and a switch button are arranged on the left side surface of the control panel, the centrifugal chamber is arranged above the inner part of the outer casing, an electronic objective lens is arranged at the left end of the inner part of the centrifugal chamber, the electronic objective lens is electrically connected with the display screen, a horizontal rotor is arranged in the middle of the inner part of the centrifugal chamber, the centrifugal rotating device is arranged at the middle position below the centrifugal chamber, a buffer device is embedded on the outer part of the centrifugal rotating device, a speed reducer is arranged under the centrifugal rotating device, a transmission device is arranged on the right side surface of the speed reducer, a servo motor is arranged on the upper right side of the transmission device, the below surface at the shell body is installed to the supporting legs, servo motor and adjust knob electric connection, display screen, adjust knob and shift knob all with control panel electric connection, though this patent can normal use, the effect of separation is not good, can not discharge the waste liquid fast, and can not conveniently come the temperature in the adjusting device according to the speed of separation, has reduced the practicality of device.
SUMMERY OF THE UTILITY MODEL
The utility model mainly provides a centrifugal separation case for immune cell separation for solve the technical problem who proposes among the above-mentioned background art.
The utility model provides a technical scheme that above-mentioned technical problem adopted does:
a centrifugal separation box for separating immune cells comprises a separation box, wherein the separation box comprises a separation mechanism, the separation mechanism comprises a separation cabin and a liquid storage cabin, a magnetic bead box is arranged at the bottom of the separation cabin, a plurality of magnetic beads are arranged on the inner bottom wall of the magnetic bead box, an electromagnet is arranged at the bottom of the magnetic bead box, a plurality of liquid discharge holes are formed in the surface of the separation cabin in an equal dividing mode, the bottom of the electromagnet is movably connected with the separation box through a first rotating shaft, a bearing and a worm wheel are arranged on the surface of the first rotating shaft, and the outer ring of the bearing is connected with the liquid storage cabin;
the separating box comprises a worm and a second rotating shaft, the worm is in transmission connection with the worm wheel, one end of the worm penetrates through the separating box to be provided with a motor, and a first transmission wheel is arranged on the surface of the worm.
Preferably, one end of the second rotating shaft is provided with a second driving wheel, the first driving wheel is in transmission connection with the second driving wheel through a transmission belt, and the surface of the second rotating shaft is equally divided into two fan blades. In the preferred embodiment, the second transmission wheel, the transmission belt and the fan blades can realize the function of quickly cooling the equipment inside the device.
Preferably, the inner wall of the separation box is provided with a cooling pipe, and the inner wall of the separation box is provided with a temperature sensor. In the preferred embodiment, the cooling pipe and the temperature sensor can realize the functions of cooling the internal temperature of the device and detecting and controlling the temperature.
Preferably, the bottom of liquid storage cabin is equipped with first liquid hole, one side of separator box is equipped with the second and goes out the liquid hole, first liquid hole is gone out liquid hole and is passed through the hose and is connected with the second liquid hole. In this preferred embodiment, through first play liquid hole, second play liquid hole and hose, can realize carrying out the effect of discharging fast with the waste liquid in the stock solution cabin.
Preferably, one side of separator box is equipped with control panel, control panel is electric connection through wire and magnetic bead, motor, cooling tube and temperature sensor. In the preferred embodiment, the control panel can control the operation of the whole device.
Preferably, the top of separator box is equipped with the damping hinge, one side of damping hinge is equipped with the case lid, the bottom of case lid is equipped with sealed piece. In the preferred embodiment, the function of sealing the separation box can be realized through the damping hinge, the box cover and the sealing block.
Preferably, the bottom of the separation box is equally provided with four shock-absorbing rubber pads. In the preferred embodiment, the damping rubber pad can realize the damping and noise reduction effects during the operation of the device.
Compared with the prior art, the beneficial effects of the utility model are that:
the utility model discloses a separation box, separating mechanism, disconnect-ing cabin, liquid storage cabin, magnetic bead, outage, first pivot, bearing, worm wheel, worm, second pivot, motor and first drive wheel have realized the separation effect of preferred, can discharge the waste liquid fast to can conveniently come the temperature in the adjusting device according to the speed of separation, satisfied the practicality of device.
The present invention will be explained in detail with reference to the drawings and specific embodiments.
Drawings
FIG. 1 is an isometric view of the overall structure of the present invention;
FIG. 2 is a cross-sectional view of the overall structure of the present invention;
fig. 3 is an enlarged view of the area a in fig. 2 according to the present invention;
fig. 4 is an enlarged view of the area B in fig. 2 according to the present invention;
fig. 5 is an enlarged view of the region C in fig. 2 according to the present invention.
In the figure: 1. a separation tank; 10. a second liquid outlet hole; 100. a transmission belt; 11. a worm; 111. a first drive pulley; 12. a second rotating shaft; 121. a second transmission wheel; 122. a fan blade; 13. a box cover; 131. a sealing block; 14. a shock-absorbing rubber pad; 2. a separating mechanism; 21. a separation chamber; 210. a drain hole; 22. a liquid storage tank; 220. a first liquid outlet hole; 23. a first rotating shaft; 231. a bearing; 232. a worm gear; 3. magnetic beads; 4. a motor; 5. a cooling tube; 51. a temperature sensor; 6. a hose; 7. a control panel; 8. a damping hinge; 9. a magnetic bead box; 91. an electromagnet.
Detailed Description
In order to facilitate understanding of the present invention, the present invention will be described more fully with reference to the accompanying drawings, in which several embodiments of the present invention are shown, but the present invention can be implemented in different forms, and is not limited to the embodiments described in the text, but rather, these embodiments are provided to make the disclosure of the present invention more thorough and comprehensive.
It will be understood that when an element is referred to as being "secured to" another element, it can be directly on the other element or intervening elements may be present, and when an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present, as the terms "vertical", "horizontal", "left", "right" and the like are used herein for descriptive purposes only.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs, and the use of the term knowledge in the specification of the present invention is for the purpose of describing particular embodiments and is not intended to limit the present invention, and the term "and/or" as used herein includes any and all combinations of one or more of the associated listed items.
In an embodiment, referring to fig. 1 to 5, a centrifugal separation tank for separating immune cells includes a separation tank 1, and is characterized in that the separation tank 1 includes a separation mechanism 2, the separation mechanism 2 includes a separation cabin 21 and a liquid storage cabin 22, a magnetic bead box 9 is disposed at the bottom of the separation cabin 21, a plurality of magnetic beads 3 are disposed on an inner bottom wall of the magnetic bead box 9, an electromagnet 91 is disposed at the bottom of the magnetic bead box 9 and connected with the bottom of the magnetic bead box 9 through a bolt, a plurality of liquid discharge holes 210 are equally disposed on the surface of the separation cabin 21, the bottom of the electromagnet 91 is movably connected with the separation tank 1 through a first rotating shaft 23 and connected with the separation tank through a bolt, a bearing 231 and a worm wheel 232 are disposed on the surface of the first rotating shaft 23, an outer ring of the bearing 231 is connected with the liquid storage cabin 22, the separation tank 1 includes a worm 11 and a second rotating shaft 12, the worm 11 is in transmission connection with the worm wheel 232, the one end of worm 11 runs through separator 1 and is equipped with motor 4, the surface of worm 11 is equipped with first drive wheel 111, through bolted connection, the one end of second pivot 12 is equipped with second drive wheel 121, through bolted connection, first drive wheel 111 is connected with second drive wheel 121 transmission through drive belt 100, the surface equipartition of second pivot 12 is equipped with two flabellums 122, through bolted connection, through second drive wheel 121, drive belt 100 and flabellum 122, can realize carrying out quick refrigerated effect to device internal plant, separator 1's inner wall is equipped with cooling tube 5, through bolted connection, separator 1's inner wall is equipped with temperature sensor 51, through bolted connection, through cooling tube 5 and temperature sensor 51, can realize cooling down the device internal temperature and detect the effect of accuse temperature.
In an embodiment, referring to fig. 1 to 4, a first liquid outlet hole 220 is formed at the bottom of the liquid storage tank 22, a second liquid outlet hole 10 is formed at one side of the separation tank 1, the first liquid outlet hole 220 is connected with the second liquid outlet hole 10 through a hose 6, a function of rapidly discharging waste liquid in the liquid storage tank 22 is realized through the first liquid outlet hole 220, the second liquid outlet hole 10 and the hose 6, a control panel 7 (model TIS00086) is arranged at one side of the separation tank 1 and is connected through a bolt, the control panel 7 is electrically connected with a magnetic bead 3(101T), a motor 4 (model aosuo-0-18-6), a cooling pipe 5 and a temperature sensor 51 (model TCN75 avaoa 713) through a lead, a function of controlling the operation of the whole device is realized through the control panel 7, a damping hinge 8 is arranged at the top of the separation tank 1, a tank cover 13 is arranged at one side of the damping hinge 8, the bottom of case lid 13 is equipped with sealed piece 131, through damping hinge 8, case lid 13 and sealed piece 131, can realize carrying out sealed effect to separator box 1, the bottom partition of separator box 1 is equipped with four cushion rubber 14, through bolted connection, through cushion rubber 14, can realize carrying out vibration/noise reduction's effect when moving the device.
The utility model discloses a concrete operation as follows:
firstly, a worker opens the box cover 13, puts in stock solution, closes the box cover 13, starts the motor 4 through the control panel 7, the motor 4 drives the worm 11 and the first driving wheel 111 to rotate, the worm 11 drives the worm wheel 232, the worm wheel 232 drives the separation chamber 21 to rotate, so that immune cells in the stock solution are separated from mixed cell populations, meanwhile, magnetic beads 30 in the magnetic bead box 9 at the bottom of the separation chamber 21 adsorb the cells on the surface of the magnetic beads, meanwhile, the electromagnet 91 at the bottom of the magnetic bead box 9 is started, so that the magnetic beads 30 are adsorbed on the inner bottom wall of the magnetic bead box 9, waste liquid is discharged out of the device through the first liquid outlet 220, the liquid outlet 210, the hose 6 and the second liquid outlet 10, meanwhile, the first driving wheel 111 drives the second driving wheel 121 to rotate through the driving belt 100, the second driving wheel 121 drives the second rotating shaft 12 and the fan blades 122 to rotate, and senses the temperature in the device through the temperature sensor 51, the temperature of the cooling pipe 5 is controlled by a control panel 7, so that the inside of the device is kept at a constant temperature.
The present invention has been described above with reference to the accompanying drawings, and it is obvious that the present invention is not limited by the above-mentioned manner, if the method and the technical solution of the present invention are adopted, the present invention can be directly applied to other occasions without substantial improvement, and the present invention is within the protection scope of the present invention.
Claims (7)
1. The centrifugal separation box for immune cell separation comprises a separation box (1) and is characterized in that the separation box (1) comprises a separation mechanism (2), the separation mechanism (2) comprises a separation cabin (21) and a liquid storage cabin (22), a magnetic bead box (9) is arranged at the bottom of the separation cabin (21), a plurality of magnetic beads (3) are arranged on the inner bottom wall of the magnetic bead box (9), an electromagnet (91) is arranged at the bottom of the magnetic bead box (9), a plurality of liquid discharge holes (210) are formed in the surface of the separation cabin (21) in an equal division mode, the bottom of the electromagnet (91) is movably connected with the separation box (1) through a first rotating shaft (23), a bearing (231) and a worm wheel (232) are arranged on the surface of the first rotating shaft (23), and the outer ring of the bearing (231) is connected with the liquid storage cabin (22);
separator box (1) is including worm (11) and second pivot (12), worm (11) are connected with worm wheel (232) transmission, the one end of worm (11) is run through separator box (1) and is equipped with motor (4), the surface of worm (11) is equipped with first drive wheel (111).
2. The centrifugal separation chamber for separating immune cells as claimed in claim 1, wherein a second transmission wheel (121) is provided at one end of the second rotation shaft (12), the first transmission wheel (111) is in transmission connection with the second transmission wheel (121) through a transmission belt (100), and two fan blades (122) are equally provided on the surface of the second rotation shaft (12).
3. The centrifugal separation tank for immune cell separation according to claim 1, characterized in that the inner wall of the separation tank (1) is provided with a cooling pipe (5), and the inner wall of the separation tank (1) is provided with a temperature sensor (51).
4. The centrifugal separation tank for immune cell separation according to claim 1, wherein a first liquid outlet hole (220) is formed at the bottom of the liquid storage tank (22), a second liquid outlet hole (10) is formed at one side of the separation tank (1), and the first liquid outlet hole (220) is connected with the second liquid outlet hole (10) through a hose (6).
5. The centrifugal separation box for immune cell separation according to claim 1, characterized in that a control panel (7) is arranged on one side of the separation box (1), and the control panel (7) is electrically connected with the magnetic beads (3), the motor (4), the cooling tube (5) and the temperature sensor (51) through wires.
6. The centrifugal separation box for immune cell separation according to claim 1, characterized in that a damping hinge (8) is arranged at the top of the separation box (1), a box cover (13) is arranged at one side of the damping hinge (8), and a sealing block (131) is arranged at the bottom of the box cover (13).
7. The centrifugal separation tank for immune cell separation according to claim 1, characterized in that the bottom of the separation tank (1) is equally provided with four shock-absorbing rubber pads (14).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202121519757.3U CN215103311U (en) | 2021-07-05 | 2021-07-05 | Centrifugal separation case is used in immune cell separation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202121519757.3U CN215103311U (en) | 2021-07-05 | 2021-07-05 | Centrifugal separation case is used in immune cell separation |
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| Publication Number | Publication Date |
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| CN215103311U true CN215103311U (en) | 2021-12-10 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN202121519757.3U Active CN215103311U (en) | 2021-07-05 | 2021-07-05 | Centrifugal separation case is used in immune cell separation |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115011557A (en) * | 2022-07-18 | 2022-09-06 | 泰州赛特生物医药科技有限公司 | Experimental identification device for non-blood-borne nucleated cells and application method thereof |
-
2021
- 2021-07-05 CN CN202121519757.3U patent/CN215103311U/en active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115011557A (en) * | 2022-07-18 | 2022-09-06 | 泰州赛特生物医药科技有限公司 | Experimental identification device for non-blood-borne nucleated cells and application method thereof |
| CN115011557B (en) * | 2022-07-18 | 2024-04-26 | 泰州赛特生物医药科技有限公司 | Non-blood-source nucleated cell experimental identification device and using method thereof |
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