CN214634335U - Batch filter device for to-be-detected liquid of high performance liquid chromatograph for drug detection - Google Patents
Batch filter device for to-be-detected liquid of high performance liquid chromatograph for drug detection Download PDFInfo
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- CN214634335U CN214634335U CN202121084393.0U CN202121084393U CN214634335U CN 214634335 U CN214634335 U CN 214634335U CN 202121084393 U CN202121084393 U CN 202121084393U CN 214634335 U CN214634335 U CN 214634335U
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- push plate
- electric telescopic
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- 239000007788 liquid Substances 0.000 title claims abstract description 30
- 239000003814 drug Substances 0.000 title claims abstract description 14
- 238000001514 detection method Methods 0.000 title claims description 9
- 229940079593 drug Drugs 0.000 title claims description 8
- 239000007791 liquid phase Substances 0.000 claims abstract description 18
- 238000001914 filtration Methods 0.000 claims abstract description 11
- 239000012528 membrane Substances 0.000 claims description 8
- 239000012071 phase Substances 0.000 description 4
- 239000000243 solution Substances 0.000 description 4
- 239000012488 sample solution Substances 0.000 description 3
- 238000004458 analytical method Methods 0.000 description 2
- 230000000903 blocking effect Effects 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- 230000001954 sterilising effect Effects 0.000 description 2
- 238000004659 sterilization and disinfection Methods 0.000 description 2
- 230000007547 defect Effects 0.000 description 1
- 238000001125 extrusion Methods 0.000 description 1
- 210000003811 finger Anatomy 0.000 description 1
- 210000005224 forefinger Anatomy 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 238000004811 liquid chromatography Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000003252 repetitive effect Effects 0.000 description 1
- 239000000523 sample Substances 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 239000012085 test solution Substances 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
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Abstract
The utility model discloses a liquid batch filter equipment is awaited measuring to high performance liquid chromatograph for medicine detects belongs to the instrument and meter field. The device includes: the liquid phase bottle fixing device comprises a supporting plate, a plurality of fixing holes and a plurality of guide columns, wherein the supporting plate is provided with a plurality of fixing holes and used for placing liquid phase small bottles; the positioning plate is provided with a plurality of guide holes for accommodating the filtering containers, guide rods which correspond to the limiting holes one by one are arranged on the positioning plate, and the guide rods are matched with the limiting holes; the driving device comprises an electric telescopic rod and a push plate, the push plate is fixedly arranged at the output end of the electric telescopic rod, and the push plate is driven to move when the electric telescopic rod acts; wherein, the positioning plate is positioned between the push plate and the supporting plate; the guide hole corresponds to the fixing hole. The utility model is convenient for the relative positioning of the filtering device and the liquid phase small bottle; the workload is simplified, the repeated operation of experimenters is reduced, and the experimental efficiency is improved.
Description
Technical Field
The utility model relates to an instrument and meter field, in particular to medicine detects and treats measuring liquid batch filter equipment with high performance liquid chromatograph.
Background
In the field of inspection and detection, a high performance liquid chromatograph is often required to be used for relevant analysis work. The solvent used by the high performance liquid chromatograph must be filtered by a 0.45 mu m filter membrane before being put into a liquid storage tank to remove mechanical impurities in the solvent so as to prevent the blockage phenomenon of a transfusion pipeline or a sample injection valve.
In a laboratory for testing and detecting medicines, when a high performance liquid chromatograph is used for preparing a test solution to be tested, the prior art generally comprises the following steps: taking down the core bar, needle seat and sheath of the disposable aseptic syringe, connecting and fixing the front end of the syringe jacket (body) with a commercially available disposable filter head, transferring the extracted or processed sample solution into the syringe jacket (body), pushing the syringe core bar to enable the solution in the body to pass through the filter head by means of external force extrusion, and filtering the solution into a liquid phase small bottle to complete the processing.
The prior art has the following defects and shortcomings: in the actual work of drug detection, it is usually encountered that a large amount of sample solutions to be detected need to be filtered by a microporous filter membrane and then measured by a high performance liquid chromatograph, and each sample solution is filtered into a bottle in times to seriously affect the experimental efficiency.
SUMMERY OF THE UTILITY MODEL
The utility model provides a liquid is waited to detect by high performance liquid chromatograph and is filtered device in batches for medicine detects can solve among the prior art and detect at liquid chromatography, the problem that the experimental efficiency that exists is low when needing to filter mobile phase.
The utility model provides a medicine detects and waits to detect liquid batch filter equipment with high performance liquid chromatograph, includes:
the liquid phase bottle fixing device comprises a supporting plate, a plurality of fixing holes and a plurality of guide columns, wherein the supporting plate is provided with a plurality of fixing holes and used for placing liquid phase small bottles;
the positioning plate is provided with a plurality of guide holes for accommodating filter containers, guide rods which correspond to the limiting holes one by one are arranged on the positioning plate, and the guide rods are matched with the limiting holes; and the number of the first and second groups,
the driving device comprises an electric telescopic rod and a push plate, the push plate is fixedly arranged at the output end of the electric telescopic rod, and the electric telescopic rod drives the push plate to move when acting; wherein,
the positioning plate is positioned between the push plate and the supporting plate;
the guide hole corresponds to the fixing hole in position.
Preferably, the supporting plate, the positioning plate and the push plate are all rectangular structures; the guide posts are four and are positioned at four corners of the supporting plate.
Preferably, the filtering container comprises a containing pipe and an ejector rod, a microporous filtering membrane is arranged in the containing pipe, and the ejector rod is movably and hermetically arranged in the containing pipe in a sliding manner and used for pushing the solution to be filtered; the outer side wall of the accommodating pipe is provided with a baffle plate, and the baffle plate is used for being supported on the guide hole; when the push plate moves, the ejector rod is pushed to move.
Preferably, the ejector rod is fixedly arranged on the push plate and corresponds to the accommodating pipe.
The utility model provides a batch filter device for liquid to be tested of a high performance liquid chromatograph for medicine detection, which is convenient to fix a liquid phase small bottle through a fixing hole and fix a filter device through a guide hole, and the guide hole corresponds to the fixing hole, thereby facilitating the relative positioning of the filter device and the liquid phase small bottle; utilize drive arrangement can once drive a plurality of filter equipment, simplified work load greatly, reduced experimenter's repetitive operation, promote experimental efficiency.
Drawings
Fig. 1 is a schematic structural diagram of a batch filtration device for a to-be-detected liquid of a high performance liquid chromatograph for drug detection according to the present invention;
FIG. 2 is a schematic cross-sectional view of the embodiment of FIG. 1;
FIG. 3 is a schematic diagram of the filter container and the liquid phase vial of FIG. 2;
FIG. 4 is an enlarged view of a portion A of FIG. 3;
fig. 5 is a schematic cross-sectional view of another embodiment of fig. 1.
Description of reference numerals:
10 a support plate; 11 a guide post; 12 fixing holes; 20, positioning a plate; 21 a guide bar; 22 a pilot hole; 30, an electric telescopic rod; 31 a push plate; 40 receiving a tube; 401 baffle plate; 41, a top rod; 411 a microporous filtration membrane; 50 liquid phase vial.
Detailed Description
In the following, an embodiment of the present invention will be described in detail with reference to the drawings, but it should be understood that the scope of the present invention is not limited by the embodiment.
The first embodiment is as follows:
as shown in fig. 1 and fig. 2, an embodiment of the utility model provides a drug detection is with high performance liquid chromatograph liquid filter equipment in batches that awaits measuring, including support, backup pad 10, locating plate 20 and drive arrangement:
the support plate 10 is provided with a plurality of fixing holes 12 for placing the liquid phase small bottles 50, the size of the fixing holes 12 is similar to the outer diameter of the liquid phase small bottles 50, the liquid phase small bottles 50 can be better supported and positioned, the support plate 10 is also provided with a plurality of guide posts 11, and the guide posts 11 are provided with limiting holes;
the positioning plate 20 is provided with a plurality of guide holes 22 for accommodating filter containers, the outer diameters of the guide holes 22 are similar to the outer diameter of the filter containers and are used for positioning the filter containers, the positioning plate 20 is provided with guide rods 21 which correspond to the guide holes 22 one by one, the guide rods 21 are matched with the limiting holes, and when the guide rods 21 extend into the limiting holes, the positioning plate 20 and the support plate 10 can be positioned and supported;
the driving device comprises an electric telescopic rod 30 and a push plate 31, the electric telescopic rod 30 is fixedly arranged on a support (not shown in the figure), the push plate 31 is fixedly arranged at the output end of the electric telescopic rod 30, and the push plate 31 is driven to move when the electric telescopic rod 30 acts; wherein,
the positioning plate 20 is positioned between the push plate 31 and the support plate 10;
the guide hole 22 corresponds to the position of the fixing hole 12.
Further, the supporting plate 10, the positioning plate 20 and the pushing plate 31 are all rectangular structures; the guide posts 11 are four and are located at four corners of the support plate 10.
When in work, the positioning plate 20 is separated from the supporting plate 10; the liquid phase small bottle 50 is fixedly placed in the fixed hole 12, the mobile phase is filled into the injector, then the injector is inversely placed through the guide hole 22, and the blocking part (the part supported by the forefinger and the middle finger) on the injector is abutted against the position of the guide hole 22, and the blocking part is larger than the outer diameter of the guide hole 22, so that the liquid phase small bottle cannot fall off;
moving the positioning plate 20 to a position corresponding to the support plate 10, matching the positioning plate 20 with the support plate 10 by means of the guide rod 21 and the limiting hole, wherein after matching, the positions of the guide hole 22 and the fixing hole 12 correspond, and the output end of the injector just extends into the liquid phase small bottle 50;
after the arrangement is finished, the electric telescopic rod 30 is started, the electric telescopic rod 30 drives the push plate 31 to move downwards to abut against the push rod of the injector, and the push rod is driven to move downwards to perform the filtering operation (the microporous filter membrane 411 is manually placed in the injector in advance).
Example two:
since the disposable sterile syringe is a medical resource, the production process is performed through links such as sterilization, the production cost is high, and the physicochemical component analysis does not require appliance sterilization, which causes resource waste, in this embodiment, as shown in fig. 3 and 4, the filter container includes a storage tube 40 and an ejector rod 41, a microporous filter membrane 411 is disposed in the storage tube 40, and the ejector rod 41 is slidably disposed in the storage tube 40 in a movable sealing manner, and is used for pushing the solution to be filtered; a baffle 401 is arranged on the outer side wall of the accommodating pipe 40, and the baffle 401 is used for being supported on the guide hole 22; when the push plate 31 moves, the push rod 41 moves.
The integrated design of the accommodating tube 40 and the microporous filter membrane 411 saves the step of manually installing and fixing the filter head and the injector in the existing treatment process, and greatly improves the operation efficiency of filtration treatment.
In other embodiments, as shown in fig. 5, the push plate 31 is fixedly provided with a push rod 41, and the push rod 41 corresponds to the storage tube 40. The ejector rod 41 and the push plate 31 are integrally designed, so that the mobile phase in the storage pipe 40 can be conveniently filled, the ejector rod 41 does not need to be detached and reloaded (when the ejector rod 41 is designed in a split mode, the ejector rod 41 needs to be pulled out firstly, and the ejector rod 41 is installed back after the mobile phase is filled), and the cooperation of the ejector rod 41 and the storage pipe 40 can be ensured through the cooperation of the guide rod 21 and the limiting hole.
The above disclosure is only for a few specific embodiments of the present invention, however, the present invention is not limited to the embodiments, and any changes that can be considered by those skilled in the art shall fall within the protection scope of the present invention.
Claims (4)
1. The utility model provides a medicine detects and waits to detect liquid filter equipment in batches with high performance liquid chromatograph which characterized in that includes:
the liquid phase bottle fixing device comprises a supporting plate, a plurality of fixing holes and a plurality of guide columns, wherein the supporting plate is provided with a plurality of fixing holes and used for placing liquid phase small bottles;
the positioning plate is provided with a plurality of guide holes for accommodating filter containers, guide rods which correspond to the limiting holes one by one are arranged on the positioning plate, and the guide rods are matched with the limiting holes; and the number of the first and second groups,
the driving device comprises an electric telescopic rod and a push plate, the push plate is fixedly arranged at the output end of the electric telescopic rod, and the electric telescopic rod drives the push plate to move when acting; wherein,
the positioning plate is positioned between the push plate and the supporting plate;
the guide hole corresponds to the fixing hole in position.
2. The device for filtering to-be-detected liquid of a high performance liquid chromatograph for drug detection according to claim 1, wherein the supporting plate, the positioning plate and the pushing plate are all rectangular; the guide posts are four and are positioned at four corners of the supporting plate.
3. The device for filtering a to-be-detected liquid of a high performance liquid chromatograph in batch for drug detection as claimed in claim 1 or 2, wherein the filter container comprises a storage tube and a push rod, the storage tube is internally provided with a microporous filter membrane, and the push rod is slidably arranged in the storage tube in a dynamic seal manner and used for pushing the to-be-filtered liquid; the outer side wall of the accommodating pipe is provided with a baffle plate, and the baffle plate is used for being supported on the guide hole; when the push plate moves, the ejector rod is pushed to move.
4. The device as claimed in claim 3, wherein the push plate is fixed to the push rod, and the push rod corresponds to the receiving tube.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202121084393.0U CN214634335U (en) | 2021-05-19 | 2021-05-19 | Batch filter device for to-be-detected liquid of high performance liquid chromatograph for drug detection |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202121084393.0U CN214634335U (en) | 2021-05-19 | 2021-05-19 | Batch filter device for to-be-detected liquid of high performance liquid chromatograph for drug detection |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN214634335U true CN214634335U (en) | 2021-11-09 |
Family
ID=78495268
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202121084393.0U Expired - Fee Related CN214634335U (en) | 2021-05-19 | 2021-05-19 | Batch filter device for to-be-detected liquid of high performance liquid chromatograph for drug detection |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN214634335U (en) |
-
2021
- 2021-05-19 CN CN202121084393.0U patent/CN214634335U/en not_active Expired - Fee Related
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| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20211109 |
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| CF01 | Termination of patent right due to non-payment of annual fee |