CN214496289U - Full-automatic nucleic acid extraction appearance of biosafety - Google Patents
Full-automatic nucleic acid extraction appearance of biosafety Download PDFInfo
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- CN214496289U CN214496289U CN202022655663.0U CN202022655663U CN214496289U CN 214496289 U CN214496289 U CN 214496289U CN 202022655663 U CN202022655663 U CN 202022655663U CN 214496289 U CN214496289 U CN 214496289U
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Abstract
The utility model discloses a full-automatic nucleic acid extraction appearance of biological safety relates to nucleic acid extraction technical field. The biological safe full-automatic nucleic acid extractor comprises a shell, wherein an extraction assembly for extracting nucleic acid is arranged in the shell, a first air outlet is formed in the top end of the shell, and a biological safety protection device is arranged at the position, located at the air outlet, of the top end of the shell; the biological safety protection device comprises a shell arranged at the top end of the shell, a fan and a high-efficiency filter, wherein the fan and the high-efficiency filter are arranged inside the shell, an air inlet of the fan corresponds to the first air outlet, and an air outlet of the fan corresponds to an air outlet of the shell. The utility model discloses neither receive the restriction of biological safety cabinet, can ensure again that measurement personnel, test sample and environment avoid infecting.
Description
Technical Field
The utility model relates to a nucleic acid extraction technical field, concretely relates to biosafety's full-automatic nucleic acid extraction appearance.
Background
In modern molecular biological assays, nucleic acid-based molecular diagnostic and detection techniques are increasingly showing crucial roles in a wide variety of fields. Is a conventional instrument for clinical examination in modern hospitals. Since the extracted sample may carry infectious viruses, aerosol is easily generated in the environment during the test, which brings great infection risk to the detection personnel. In the prior art, for the problem of aerosol, the solution is to place the nucleic acid extractor in a biological safety cabinet with all exhaust air, but the size of the nucleic acid extractor placed in the biological safety cabinet cannot be too large due to the limitation of the size of the biological safety cabinet, namely the nucleic acid extractor cannot be suitable for a multi-channel large-size nucleic acid extractor.
SUMMERY OF THE UTILITY MODEL
The utility model provides a neither receive the restriction of biological safety cabinet, can ensure again that measurement personnel, test sample and environment avoid the full-automatic nucleic acid extraction appearance of the biological safety of infection.
In order to solve the technical problem, the utility model provides a technical scheme as follows:
a biosafety full-automatic nucleic acid extractor comprises a shell, wherein an extraction assembly for extracting nucleic acid is arranged in the shell, a first air outlet is formed in the top end of the shell, and a biosafety protection device is arranged at the position, located at the air outlet, of the top end of the shell;
the biological safety protection device comprises a shell arranged at the top end of the shell, a fan and a high-efficiency filter, wherein the fan and the high-efficiency filter are arranged inside the shell, an air inlet of the fan corresponds to the first air outlet, and an air outlet of the fan corresponds to an air outlet of the shell.
Furthermore, the high-efficiency filter is positioned below the air inlet of the fan or above the air outlet of the fan.
Furthermore, an air guide cover is arranged below the air inlet of the fan inside the shell.
Further, an air outlet of the shell is provided with a primary filter.
Further, be provided with the workstation in the shell, the subassembly of drawing including set up in vertical oscillation device, horizontal oscillation incubation device and heating mechanism on the workstation.
Furthermore, vertical oscillation device sets up first frame and vibration mechanism on the workstation including sliding, be provided with in the first frame and be used for the drive vibrate the first drive arrangement that the mechanism reciprocated, vibrate the mechanism include bar magnet cover subassembly, with bar magnet cover subassembly matched with bar magnet subassembly and drive bar magnet subassembly second drive arrangement of relative bar magnet cover subassembly up-and-down motion.
Furthermore, a drip-proof plate is arranged below the magnetic rod sleeve assembly, and a third driving device used for driving the drip-proof plate to rotate relative to the magnetic rod sleeve assembly is arranged on the rack.
Furthermore, the horizontal oscillation incubation device comprises a second rack arranged on the workbench and an eccentric wheel driving device arranged on the second rack, the eccentric wheel driving device is in driving connection with the first incubation plate, and an elastic part is arranged between the eccentric wheel driving device and the second rack.
Further, the heating mechanism comprises a heating mechanism arranged on the lower end face of the first incubation plate and a heat insulation mechanism arranged between the first incubation plate and the eccentric wheel driving device.
Further, the extraction assembly still including set up in cold-stored save and the integrated device is hatched in the heating on the workstation, cold-stored save and the integrated device is hatched in the heating including set up in third frame on the workstation, set up in board is hatched to the second in the third frame, the bottom that the board was hatched to the second is provided with refrigeration piece and fin, the fan is installed through the mounting bracket in the bottom of fin.
Compared with the prior art, the utility model discloses following beneficial effect has:
the utility model discloses a biological safety's full-automatic nucleic acid extraction appearance sets up biological safety device through the top at the shell, and the measurement personnel is when the operation extraction element draws nucleic acid, and the inside air of nucleic acid extraction appearance prevents that harmful gas such as aerosol from getting into the external environment through high efficiency filter's filtration discharge nucleic acid extraction appearance under the effect of fan, ensures that measurement personnel, test sample and environment avoid infecting. Meanwhile, due to the arrangement of the biological safety placing device, the nucleic acid extractor does not need to be placed in a biological safety cabinet for nucleic acid extraction operation, the limitation of the size of the biological safety cabinet is eliminated, and the detection personnel can select the nucleic acid extractor with various sizes and specifications according to the requirement of nucleic acid extraction amount.
Drawings
FIG. 1 is a schematic structural view of the biosafety automatic nucleic acid extractor of the present invention;
FIG. 2 is a schematic structural view of a biosafety protection device in the biosafety full-automatic nucleic acid extractor of the present invention;
FIG. 3 is a schematic structural view of a vertical oscillation device in the biosafety full-automatic nucleic acid extractor of the present invention;
FIG. 4 is a schematic structural view of a horizontal oscillation device and a heating mechanism in the biosafety full-automatic nucleic acid extractor of the present invention;
FIG. 5 is a schematic structural view of the integrated device for refrigerating, preserving, heating and incubating in the fully automatic nucleic acid extractor of biological safety of the present invention.
Detailed Description
In order to make the technical problems, technical solutions and advantages to be solved by the present invention clearer, the following detailed description will be given with reference to the accompanying drawings and specific embodiments.
The utility model provides a biosafety full-automatic nucleic acid extractor, as shown in fig. 1 to 5, comprising a shell 5, wherein an extracting component for extracting nucleic acid is arranged inside the shell 5, a first air outlet (not shown) is arranged at the top end of the shell 5, and a biosafety protection device 4 is arranged at the position, located at the air outlet, of the top end of the shell 5;
The utility model discloses a biological safety's full-automatic nucleic acid extraction appearance sets up biological safety device 4 through the top at shell 5, and when testing personnel extracted the subassembly and drawed nucleic acid and operated in the operation, the inside air of nucleic acid extraction appearance prevented harmful gas such as aerosol from getting into the external environment through the filtration discharge nucleic acid extraction appearance of high efficiency filter 405 under the effect of fan 403, ensured that testing personnel, test sample and environment avoid infecting. Meanwhile, due to the arrangement of the biological safety protection device 4, the nucleic acid extractor does not need to be placed in a biological safety cabinet for nucleic acid extraction operation, the limitation of the size of the biological safety cabinet is eliminated, and the detection personnel can select the nucleic acid extractor with various sizes and specifications according to the requirement of nucleic acid extraction amount.
The utility model discloses an embodiment, high efficiency filter 405 can be located the air intake 401 below of fan 403, also can be located the top of the air outlet of fan 403, all can realize the effective filtration to contaminated air.
In order to ensure that the polluted air generated inside the nucleic acid extractor can be exhausted after being filtered by the biological safety protection device 4, an air guide cover 402 can be arranged inside the shell 404 and below the air inlet 401 of the fan 403.
When carrying out high efficiency filtration to contaminated air, inside for preventing that outside impurity from getting into biological safety device 4 and nucleic acid extraction appearance through the air outlet of casing 404, can be provided with primary filter 406 in the air outlet department of casing 404.
The utility model discloses an in the embodiment, be provided with workstation 6 in the shell 5, the extraction element vibrates incubation device 2 and heating mechanism 208 including vertical oscillation device 1, the level that sets up on workstation 6.
Specifically, vertical oscillation device 1 sets up first frame 112 and the oscillation mechanism on workstation 6 including sliding, is provided with the first drive arrangement that is used for driving the oscillation mechanism to reciprocate on first frame 112, and the oscillation mechanism includes bar magnet cover subassembly 108, with bar magnet cover subassembly 108 matched with bar magnet subassembly 107 and the second drive arrangement of the relative bar magnet cover subassembly 108 up-and-down motion of drive bar magnet subassembly 107.
The first frame 112 and the table 6 may slide by using a structure in which the first motor 101 drives the first timing belt.
The first driving device may adopt a structure form that the second motor 102 drives the second synchronous belt 103, and the magnetic rod sleeve assembly 108 is fixedly connected to the second synchronous belt 103 and guided by adopting a structure of a guide rail 111.
The second driving device can also adopt a structural form that a third motor 105 drives a third synchronous belt 104, the third motor 105 is fixedly connected to a magnetic rod sleeve assembly 108, a driven wheel of the third synchronous belt 104 is connected with a ball screw 106, a magnetic rod assembly 107 is fixedly connected to the ball screw 106, and the third motor drives the ball screw 106 to rotate through the third synchronous belt 104, so as to drive the magnetic rod assembly 107 to move up and down relative to the magnetic rod sleeve assembly 108.
The utility model discloses a first drive arrangement and second drive arrangement drive respectively and vibrate the vibration that mechanism (bar magnet subassembly 107 and bar magnet cover subassembly 108) and the relative bar magnet cover subassembly 108 high frequency up-and-down motion of bar magnet subassembly 107 produced vertical direction, realize the mixing of reagent.
The utility model discloses an embodiment, for preventing that vertical oscillation device during operation reagent from dripping to workstation 6 and producing cross contamination, can be provided with antidrip board 109 in bar magnet cover subassembly 108's below, be provided with in the frame and be used for driving the rotatory third drive arrangement 110 of antidrip board 109 relative bar magnet cover subassembly 108. The third driving device 110 may be in the form of a stepping motor, and directly drives the drip-proof plate 109 to rotate up and down relative to the magnetic rod sleeve assembly 108.
The utility model discloses an embodiment, horizontal oscillation hatching apparatus 2 can be including setting up second frame 201 on workstation 6, setting up eccentric wheel drive 202 on second frame 201, and eccentric wheel drive 202 drive is connected with first hatching board 206 and reaction plate 207, is provided with elastic component 203 between eccentric wheel drive 202 and the second frame 201. The elastic member 203 may be four springs uniformly arranged between the second frame 201 and the eccentric wheel driving apparatus 202.
The eccentric wheel driving device 202 adopts a structure that the fourth motor drives the eccentric wheel 205, the fourth motor drives the eccentric wheel 205 to rotate, and the first incubation plate 206 above is driven to vibrate in the horizontal direction due to the inertia effect of the eccentric wheel 205 and the elastic force effect of the elastic piece 203, so that the uniform mixing of the reagent is realized.
The utility model discloses a vertical shock vibrates the structural style that combines together with the level, can make more abundant of reagent mixing, is favorable to the reaction of reagent to draw.
In addition, the heating mechanism 208 may also be directly disposed on the horizontal oscillation incubation device 2, and specifically includes the heating mechanism 208 disposed on the lower end surface of the first incubation plate 206 and the heat insulation mechanism 204 disposed between the first incubation plate 206 and the eccentric wheel 205 driving device 202. The heating mechanism 208 may take the form of a heating wire, and the thermal insulation mechanism 204 is used to prevent heat generated by the heating mechanism 208 from being transferred to mechanisms other than the first incubation plate 206.
The utility model discloses an in the embodiment, draw the subassembly still including setting up cold-stored saving and the heat incubation integrated device 3 on workstation 6, cold-stored saving and heat incubation integrated device 3 is including setting up third frame 302 on workstation 6, setting up board 301 is hatched to the second on third frame 302, and the bottom that board 301 was hatched to the second is provided with refrigeration piece 303 and fin 304, and fan 306 is installed through mounting bracket 305 in the bottom of fin 304. The refrigerating plate 303 has a refrigerating function after being energized in a forward direction, and has a heating function after being energized in a reverse direction. The third frame 302 may be made of a heat insulating material, which has a heat insulating effect.
The foregoing is a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, a plurality of improvements and decorations can be made without departing from the principle of the present invention, and these improvements and decorations should also be regarded as the protection scope of the present invention.
Claims (10)
1. A biological safe full-automatic nucleic acid extractor comprises a shell, and is characterized in that an extraction assembly for extracting nucleic acid is arranged in the shell, a first air outlet is formed in the top end of the shell, and a biological safety protection device is arranged at the position, located at the air outlet, of the top end of the shell;
the biological safety protection device comprises a shell arranged at the top end of the shell, a fan and a high-efficiency filter, wherein the fan and the high-efficiency filter are arranged inside the shell, an air inlet of the fan corresponds to the first air outlet, and an air outlet of the fan corresponds to an air outlet of the shell.
2. The biosafety full-automatic nucleic acid extractor according to claim 1, wherein the high efficiency filter is located below an air inlet of the blower or above an air outlet of the blower.
3. The biosafety full-automatic nucleic acid extractor according to claim 2, wherein an air guide cover is arranged in the shell below the air inlet of the fan.
4. The biosafety full-automatic nucleic acid extractor according to claim 1, wherein a primary filter is disposed at the air outlet of the housing.
5. The biosafety full-automatic nucleic acid extractor according to any one of claims 1 to 4, wherein a workbench is arranged in the housing, and the extraction assembly comprises a vertical oscillation device, a horizontal oscillation incubation device and a heating mechanism which are arranged on the workbench.
6. The biosafety full-automatic nucleic acid extraction instrument according to claim 5, wherein the vertical oscillation device comprises a first frame and an oscillation mechanism which are slidably arranged on the workbench, a first driving device for driving the oscillation mechanism to move up and down is arranged on the first frame, and the oscillation mechanism comprises a magnetic bar sleeve component, a magnetic bar component matched with the magnetic bar sleeve component and a second driving device for driving the magnetic bar component to move up and down relative to the magnetic bar sleeve component.
7. The apparatus according to claim 6, wherein a drip-proof plate is disposed below the magnetic rod sleeve assembly, and a third driving device for driving the drip-proof plate to rotate relative to the magnetic rod sleeve assembly is disposed on the rack.
8. The biosafety full-automatic nucleic acid extractor according to claim 5, wherein the horizontal oscillation incubation device comprises a second frame disposed on the working platform, and an eccentric wheel driving device disposed on the second frame, the eccentric wheel driving device is connected with the first incubation plate in a driving manner, and an elastic member is disposed between the eccentric wheel driving device and the second frame.
9. The biosafety full-automatic nucleic acid extractor according to claim 8, wherein the heating mechanism comprises a heating mechanism disposed on the lower end face of the first incubation plate and a heat insulation mechanism disposed between the first incubation plate and the eccentric wheel driving device.
10. The biosafety full-automatic nucleic acid extractor according to claim 5, wherein the extraction assembly further comprises a refrigerating preservation and heating incubation integrated device arranged on the workbench, the refrigerating preservation and heating incubation integrated device comprises a third rack arranged on the workbench and a second incubation plate arranged on the third rack, a refrigerating sheet and a cooling sheet are arranged at the bottom of the second incubation plate, and a fan is arranged at the bottom end of the cooling sheet through a mounting rack.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202022655663.0U CN214496289U (en) | 2020-11-17 | 2020-11-17 | Full-automatic nucleic acid extraction appearance of biosafety |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202022655663.0U CN214496289U (en) | 2020-11-17 | 2020-11-17 | Full-automatic nucleic acid extraction appearance of biosafety |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN214496289U true CN214496289U (en) | 2021-10-26 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202022655663.0U Active CN214496289U (en) | 2020-11-17 | 2020-11-17 | Full-automatic nucleic acid extraction appearance of biosafety |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN214496289U (en) |
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2020
- 2020-11-17 CN CN202022655663.0U patent/CN214496289U/en active Active
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