CN214259400U - 圆形钉合装置和外壳组合件 - Google Patents
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Abstract
本文公开了一种圆形钉合装置，其包括手动操作的触发器，所述触发器适于在击发触发器的单次致动期间允许在切割组织之前形成缝合钉。所述钉合装置在缝合钉形成期间使组织的拉伸和移动最小化，以改善缝合钉的形成。本文还公开了一种外壳组合件。通过分离所述钉合装置的缝合钉形成和组织切割功能，所述钉合装置还减小了使所述击发触发器移动通过击发行程所需要的力的量，从而减小了在所述钉合装置致动期间临床医生手上的应力。
Description
技术领域
本公开涉及钉合装置，更具体地，涉及将组织的切割延迟至缝合钉形成之后的圆形钉合装置。
背景技术
常规的手动圆形钉合装置包括：细长主体、支撑在细长主体远端部分上的外壳组合件，以及可移动地支撑在与外壳组合件相邻的细长主体远端部分上的砧座组合件。外壳组合件包括外壳壳体、支撑在外壳壳体上的钉仓、推动器组合件以及支撑在推动器组合件上的刀具。钉仓支撑多个缝合钉。推动器组合件包括缝合钉推动元件，其可移动地穿过钉仓，以穿过组织将多个缝合钉从钉仓中弹出并抵靠砧座组合件形成缝合钉。刀具联接到缝合钉推动元件并可与其一起移动，以在缝合钉形成时解剖夹在外壳组合件和砧座组合件之间的组织。
实用新型内容
因此，期望能改善缝合钉的形成。此外，还期望能够更加便于医生操作。
本公开的一个方面涉及一种圆形钉合装置，其包括手柄组合件、细长主体和外壳组合件。手柄组合件包括击发触发器。细长主体由手柄组合件支撑并且包括近端部分和远端部分。外壳组合件支撑在细长主体的远端部分上，并且包括限定空腔的外壳壳体、钉仓、限定纵向孔的推动器、刀架和刀具。钉仓支撑在外壳组合件上并支撑多个缝合钉。刀架可在推动器的纵向孔内移动，刀具支撑在刀架上。推动器可在外壳壳体的空腔内从缩回位置移动到前进位置，以从钉仓中弹出多个缝合钉。砧座组合件支撑在细长主体的远端部分上，并且可相对于外壳组合件在打开和夹紧位置之间移动。刀架适于可释放地接合推动器，并且可在缩回位置和中间位置之间移动，以将推动器从其缩回位置移动到其前进位置，随后可独立于推动器从其中间位置移动到前进位置，以推进刀具切割组织。
在实施例中，击发触发器联接到刀架上，使得击发触发器移动通过致动行程会将刀架从其缩回位置移动到其前进位置。
在一些实施例中，击发触发器可手动移动通过致动行程。
在某些实施例中，刀架包括至少一个突片，该突片可从与推动器接合以将刀架的远端移动转换为推动器的远端移动的第一位置移动到允许刀架独立于推动器向远端前进的第二位置。
在实施例中，所述至少一个突片中的每一个支撑在弹性臂上。
在一些实施例中，支撑至少一个突片中的每一个的弹性臂以悬臂的方式支撑在刀架上。
在某些实施例中，外壳组合件包括壳体，该壳体包括至少一个纵向肋，该纵向肋定位成接合弹性臂，该弹性臂支撑至少一个突片中的每一个，以在推动器向其前进位置移动时将至少一个突片中的每一个保持在第一位置。
在实施例中，推动器和刀架中的一个包括可断裂环，推动器和刀架中的另一个包括定位成与可断裂环接合的环形突起。
在一些实施例中，可断裂环适于在推动器接近其前进位置时断裂，以便于刀架独立于推动器移动。
本公开的一个方面涉及一种外壳组合件，其包括限定空腔的外壳壳体、钉仓、限定纵向孔的推动器、刀架和刀具。钉仓支撑在外壳组合件上并支撑多个缝合钉。刀架可在推动器的纵向孔内移动，刀具支撑在刀架上。推动器可在外壳壳体的空腔内从缩回位置移动到前进位置，以从钉仓中弹出多个缝合钉。刀架适于接合推动器，并且可在缩回位置和中间位置之间移动，以将推动器从其缩回位置移动到其前进位置，随后可独立于推动器从其中间位置移动到前进位置，以推进刀具切割组织。
本公开的一个方面涉及一种外壳组合件，其包括限定空腔的外壳壳体、钉仓、限定纵向孔的推动器、刀架和刀具。钉仓支撑在外壳组合件上并支撑多个缝合钉。推动器限定纵向孔，并且可在外壳壳体的空腔内从缩回位置移动到前进位置，以将多个钉从钉仓排出。刀架可在推动器的纵向孔内移动并支撑刀具，其中刀架可释放地联接到推动器上并可独立于推动器移动以在缝合钉形成之后切割组织。
本公开的圆形钉合装置适于在击发触发器的单次致动期间允许在切割组织之前形成缝合钉。此外，本公开的圆形钉合装置还通过分离钉合装置的缝合钉形成和组织切割功能，减小了使击发触发器移动通过击发行程所需要的力的量，从而减小了在钉合装置致动时临床医生手上的应力。
附图说明
本文结合附图对本实用新型公开的钉合装置的各种实施例进行了描述，其中：
图1是所公开的外科钉合装置的示范性实施例的侧视透视图，其中钉合装置的砧座组合件处于打开或未夹紧位置；
图2是图1所示的外科钉合装置的远端部分的侧视分解透视图；
图3是图2所示的钉合装置远端部分的外壳壳体远端的侧视透视图；
图4是图2所示的钉合装置远端部分的刀架的侧视透视图；
图5是图1中所示的钉合装置远端部分的侧视透视图，其中移除了外壳壳体并且砧座组合件处于夹紧位置；
图6是图1所示的钉合装置远端部分的侧视透视图，其中砧座组合件处于夹紧位置；
图7是沿图3的剖面线7-7截取的剖视图；
图8是沿图7的剖面线8-8截取的剖视图；
图9是图1所示的钉合装置远端部分的侧视剖视图，其中砧座组合件处于夹紧位置，并且刀架前进到中间位置以形成缝合钉；
图10是通过图1所示的钉合装置远端部分的侧视剖视图，其中砧座组合件处于夹紧位置，而刀架处于前进位置以切割组织；
图11是图1所示的钉合装置的缝合钉推动器的可选实施例的侧视剖视图；
图12是图1所示的钉合装置刀架的侧视透视图；
图13是穿过图1所示的钉合装置远端部分的侧视剖视图，包括处于夹紧位置的图11的推动器和图12的刀架以及处于缩回位置的刀架；
图14是图13所示的指示区域的细节的放大视图；
图15是通过图1所示的钉合装置远端部分的侧视剖视图，其中砧座组合件处于夹紧位置，并且刀架前进到缝合钉形成并且开始切割组织的位置；以及
图16是图15中所示的指示区域的细节的放大视图。
具体实施方式
本文结合附图对本实用新型所公开的钉合装置进行了详细描述，其中在几个视图的每一个中，相同的附图标记表示相同或相应的元件。然而，应当理解的是，所公开的实施例仅仅是本公开的示范性实施例，并且可以以各种形式实施。为了避免以不必要的细节模糊本公开，没有对公知的功能或构造进行详细描述。因此，本文公开的具体结构和功能细节不应被解释为限制性的，而仅仅是作为权利要求的基础和作为用于教导本领域技术人员以实际上任何适当的详细结构不同地使用本公开的代表性基础。
在本说明书中，术语“近端”通常用于指装置的更靠近临床医生的部分，而术语“远端”通常用于指装置的更远离临床医生的部分。此外，术语“临床医生”通常用于指医务人员，包括医生、护士和辅助人员。
所公开的圆形钉合装置是手动操作的钉合装置，其包括手动操作的触发器，该触发器适于在击发触发器的单次致动期间允许在切割组织之前形成缝合钉。所述钉合装置在缝合钉形成期间使组织的拉伸和移动最小化，以改善缝合钉的形成。通过分离钉合装置的缝合钉形成和组织切割功能，钉合装置还减小了使击发触发器移动通过击发行程所需要的力的量，从而减小了在钉合装置致动时临床医生手上的应力。
图1示出了所公开的圆形钉合装置的示范性实施例，其通常示为钉合装置10。钉合装置10包括手柄组合件12、细长主体14、外壳组合件16和砧座组合件18，砧座组合件18被支撑用于在如下所述的间隔且接近的位置之间相对于外壳组合件16移动。砧座组合件18具有砧座轴19，其适于可释放地联接到如本领域已知的钉合装置10的接近机构(未示出)。细长主体14具有远端部分14a和近端部分14b。在实施例中，外壳组合件16包括近端部分20，其可释放地联接到细长主体14的远端部分14a上。可选择地，外壳组合件16可以固定地紧固到细长主体部分14上。
手柄组合件12包括支撑击发触发器24和接近旋钮25的固定把手 22。接近旋钮25可致动，以使砧座组合件18相对于外壳组合件16 在打开位置与夹紧位置之间移动。击发触发器24可移动通过致动行程，以控制钉合装置10的各种功能的操作，包括从外壳组合件16击发缝合钉和组织的切割或去除。
图2示出了图1所示的钉合装置10的外壳组合件16。外壳组合件16包括外壳壳体30、推动器32、刀架34、支撑在刀架34上的环形刀具36、钉仓38和支撑在钉仓38内的多个缝合钉40。钉仓38是环形的，并且限定钉凹座42的环形排。每个钉凹座42支撑多个缝合钉40中的一个。推动器32包括限定纵向孔44a的主体44，并包括具有多个指状件46的远端部分。多个指状件46中的每一个容纳在钉仓 38内，并可移动通过钉仓38的钉凹座42中相应的一个，以当推动器 32在外壳壳体30内从缩回位置向前进位置移动时将缝合钉40从钉凹座38中弹出。
图3示出了外壳组合件16的外壳壳体30。外壳壳体16包括彼此间隔开的外壳体部分50和内壳体部分52，以限定环形空腔54。外壳壳体30的内壳体部分52限定通孔56，当砧座组合件18移动到夹紧位置以使砧座组合件18与外壳组合件16的钉仓38对准时，该通孔接收砧座组合件18的砧座轴19(图1)。内壳体部分52包括支撑纵向肋 58的外表面，纵向肋58定向位于外壳壳体16的环形空腔54内。外壳壳体30还包括在内部壳体部分52和外部壳体部分50之间延伸的支柱59。支柱59限制刀架34在外壳壳体30内的纵向移动，如下面详细描述的。
刀架34容纳在外壳壳体30的环形空腔54内和推动器32内，并包括环形主体60。环形体60限定纵向通孔60a并具有远端部分62和近端部分64。在实施例中，远端部分62限定环形凹部66，所述环形凹部66接收环形刀具36的近端以将刀具36固定到刀架34上。刀具 36还可具有突片70(图2)，与刀具架34接合以进一步将刀具36固定到刀具架34上。可选地，可以使用其它紧固技术将刀具36固定到刀架34上。
刀架36的环形主体60的近端部分64由被纵向槽76间隔开的支腿74限定。当刀架34容纳在外壳壳体30的环形空腔54中时，纵向槽76容纳外壳壳体30的支柱59，以限制刀架34在外壳壳体30内的纵向移动。刀架34的环形主体60的近端部分支撑联接元件86。联接元件86适于接合支撑在细长主体14内的驱动元件(未示出)上，以将刀架34联接到击发触发器(图1)。
图5示出了刀架34的远端部分，其中刀架容纳在推动器32的纵向孔44a内。如图所示，刀架34的环形主体60支撑一个或多个弹性悬臂80。在实施例中，每一个臂80具有由环形主体60支撑的远端和支撑突片82的远端。突片82从臂80径向向外延伸，并且定位成接合推动器32的近端部分，使得刀架34的移动实现推动器32在外壳壳体 30的环形空腔54内在缩回位置和前进位置之间的远端移动，如下面进一步详细描述的。刀架34的悬臂80是弹性的，并且当推动器32 已经到达其前进位置时可以向内弯曲到刀架34的纵向通孔60a中，以允许刀架34在形成缝合钉切割组织之后独立于推动器32向远端移动。突片82可以定位成与推动器32的近端接合。或者，可设想其它配置。如图5所示，推动器32的近端部分可以包括细长的槽或槽口84。槽口84容纳外壳壳体30的支柱59(图3)，以在外壳壳体30内正确地对准推动器32。
图5-8示出了钉合装置10的远端部分，其中在致动击发触发器 24(图1)之前砧座组合件18处于围绕组织“T”的夹紧位置。在该位置，刀架34和推动器32在外壳壳体30内处于它们的缩回位置。刀架32的悬臂80支承在外壳壳体30的内壳部分52的纵向肋58上。当悬臂80支撑在纵向肋58上时，臂80从刀架34向外变形，以迫使突片82向外成纵向对准和/或与推动器32接合。
图9示出了钉合装置10，其中当击发触发器24(图1)移动通过致动行程并且缝合钉40在组织“T”中形成时，砧座组合件18处于围绕组织“T”的夹紧位置。最初，当开击发触发器24时，刀架34 沿箭头“A”所示的方向前进。当刀架34前进时，悬臂80上的突片 82与推动器32接合，以使推动器32与刀架34一起沿箭头“B”所示的方向前进。当推动器32在外壳壳体30内向远端移动时，推动器32 的指状件46穿过钉仓38的钉凹座42，以抵靠砧座组合件18推进并形成缝合钉40。在该位置，刀具36尚未接合组织“T”。或者，当完成缝合钉形成时，刀具36可以与组织“T”接触。
如图10所示，当刀架34在箭头“A”所示的方向上前进到刀架 34的悬臂80从外壳壳体30的内壳部分52上的纵向肋58的远端96 离开的位置时，悬臂80由于臂80的弹性向内移动，使得突片82与推动器32脱离。当这种情况发生时，刀架34将独立于推动器32向远端前进或移动，以使刀具36沿箭头“C”的方向前进，从而切割组织“T”。突片82的远端可以包括斜面98，以允许突片82和推动器32之间的接合，从而帮助臂80向内移动，以便于突片82和推动器32的分离。
如上面简要讨论的，将钉合装置10的两种功能(即，缝合钉的形成和切割)分开，使得致动钉合装置10的击发触发器24所需的力减小，并且在缝合钉形成时使组织的拉动或拉伸最小化，以改善缝合钉的形成。
图12-16示出了所公开的钉合装置10(图1)的另一个示范性实施例，除了下面进一步详细描述的对推动器132和刀架134的修改之外，该实施例与上述实施例相似。
除了推动器32的内壁包括伸入到推动器132的纵向孔144a中的易碎或可断裂环132a(图11)之外，推动器132与推动器32(图2) 基本相同。另外，刀架134基本上类似于刀架34，只是悬臂80被去除，并且诸如圈环180(图12)等突起形成在刀架134的远端部分162 上。
图13示出了钉合装置10(图1)的远端部分，其中砧座组合件 18在击发触发器24(图1)致动之前处于围绕组织“T”的夹紧位置。在该位置，刀架134和推动器132在外壳壳体30内处于它们的缩回位置。刀架134上的突起(例如，圈环180)定位成紧邻推动器132的可断裂环132a并与该可断裂环132a对准。尽管刀架134的圈环180 显示为与可断裂环132a接合，但是这两个部件仅需要在致动击发触发器24(图1)之前彼此对准。
图15和16示出了钉合装置10，当击发触发器24(图1)移动通过致动行程时，砧座组合件18处于围绕组织“T”的夹紧位置。最初，当致动击发触发器24(图1)时，刀架134沿箭头“D”所示的方向前进。当刀架134前进时，刀架134上的圈环180与推动器132上的可断裂环132a接合，以使推动器132与刀架34一起沿箭头“D”所示的方向前进。当推动器132在外壳壳体30内向远端移动时，推动器 132的指状件146穿过钉仓38的钉凹座42，以抵靠砧座组合件18推进并形成缝合钉40。在该位置，刀具136尚未接合组织“T”。或者，当完成缝合钉形成时，刀具136可以与组织“T”接触。
当缝合钉完成形成时，推动器132的前进通过钉仓38和推动器 132之间的接合而受阻。当这种情况发生时，通过增加刀架132的圈环180施加到推动器132的可断裂环132a上的力超过阈值，可断裂环 132a从推动器132的内壁上被剪切，以允许刀架132独立于推动器132 沿箭头“E”指示的方向向远端移动，以切割组织“T”。
如上面简要讨论的，将钉合装置10的两种功能(即，缝合钉的形成和切割)分开，使得致动钉合装置10的击发触发器24所需的力减小，并且在缝合钉形成时使组织的拉动或拉伸最小化，以改善缝合钉的形成。
本领域技术人员将理解，在本文具体描述并在附图中示出的装置和方法是非限制性的示范性实施例。可以设想，结合一个示范性实施例说明或描述的元件和特征可以与另一个的元件和特征组合，而不脱离本公开的范围。同样，所属领域的技术人员将基于上述实施例了解本公开的其它特征和优点。因此，本公开不受特别示出和描述的内容限制，而是由所附权利要求限定。
Claims (20)
1.一种圆形钉合装置，其包含：
包括击发触发器的手柄组合件；
由所述手柄组合件支撑的细长主体，所述细长主体具有近端部分和远端部分；
支撑在所述细长主体的所述远端部分上的外壳组合件，所述外壳组合件包括限定空腔的外壳壳体、支撑在所述外壳壳体上的钉仓、限定纵向孔的推动器、能够在所述纵向孔内移动的刀架，以及支撑在所述刀架上的刀具，所述钉仓支撑多个缝合钉，并且所述推动器能够在所述外壳壳体的所述空腔内从缩回位置移动到前进位置，以从所述钉仓中弹出所述多个缝合钉；和
支撑在所述细长主体的所述远端部分上的砧座组合件，并且所述砧座组合件能够相对于所述外壳组合件在打开位置和夹紧位置之间移动；
其特征在于，所述刀架接合所述推动器，并且能够在缩回位置和中间位置之间移动，以将所述推动器从其缩回位置移动到其前进位置，随后能够独立于所述推动器从其中间位置移动到前进位置，以推进所述刀具切割组织。
2.根据权利要求1所述的圆形钉合装置，其特征在于，所述击发触发器联接到所述刀架上，使得所述击发触发器移动通过致动行程会将所述刀架从其缩回位置移动到其前进位置。
3.根据权利要求2所述的圆形钉合装置，其特征在于，所述击发触发器能够手动地移动通过所述致动行程。
4.根据权利要求1所述的圆形钉合装置，其特征在于，所述刀架包括至少一个突片，所述至少一个突片能够从与所述推动器接合以将所述刀架的远端移动转换为所述推动器的远端移动的第一位置移动到允许所述刀架独立于所述推动器向远端前进的第二位置。
5.根据权利要求4所述的圆形钉合装置，其特征在于，所述至少一个突片中的每一个支撑在弹性臂上。
6.根据权利要求5所述的圆形钉合装置，其特征在于，支撑所述至少一个突片中的每一个的所述弹性臂以悬臂的方式支撑在所述刀架上。
7.根据权利要求5所述的圆形钉合装置，其特征在于，所述外壳组合件包括壳体，所述壳体包括至少一个纵向肋，所述至少一个纵向肋定位成接合支撑所述至少一个突片中的每一个的所述弹性臂，以在所述推动器向其前进位置移动时将所述至少一个突片中的每一个保持在所述第一位置。
8.根据权利要求1所述的圆形钉合装置，其特征在于，所述推动器和所述刀架中的一个包括可断裂环，并且所述推动器和所述刀架中的另一个包括被定位成与所述可断裂环接合的环形突起。
9.根据权利要求8所述的圆形钉合装置，其特征在于，所述可断裂环适于在所述推动器接近其前进位置时断裂，以便于所述刀架独立于所述推动器移动。
10.一种外壳组合件，其包含：
限定空腔的外壳壳体；
支撑在所述外壳壳体上的钉仓，所述钉仓支撑多个缝合钉；
限定纵向孔的推动器；
能够在所述推动器的所述纵向孔内移动的刀架；和
支撑在所述刀架上的刀具；
其特征在于，所述推动器能够在所述外壳壳体的所述空腔内从缩回位置移动到前进位置，以从所述钉仓中弹出所述多个缝合钉，并且所述刀架接合所述推动器并且能够在缩回位置和中间位置之间移动，以将所述推动器从其缩回位置移动到其前进位置，随后能够独立于所述推动器从其中间位置移动到前进位置，以推进所述刀具切割组织。
11.根据权利要求10所述的外壳组合件，其特征在于，击发触发器联接到所述刀架上，使得所述击发触发器移动通过致动行程会将所述刀架从其缩回位置移动到其前进位置。
12.根据权利要求10所述的外壳组合件，其特征在于，所述刀架包括至少一个突片，所述至少一个突片能够从与所述推动器接合以将所述刀架的远端移动转换为所述推动器的远端移动的第一位置移动到允许所述刀架独立于所述推动器向远端前进的第二位置。
13.根据权利要求12所述的外壳组合件，其特征在于，所述至少一个突片中的每一个支撑在弹性臂上。
14.根据权利要求13所述的外壳组合件，其特征在于，支撑所述至少一个突片中的每一个的所述弹性臂以悬臂的方式支撑在所述刀架上。
15.根据权利要求13所述的外壳组合件，其特征在于，所述外壳组合件包括壳体，所述壳体包括至少一个纵向肋，所述至少一个纵向肋定位成接合支撑所述至少一个突片中的每一个的所述弹性臂，以在推动器向其前进位置移动时将所述至少一个突片中的每一个保持在所述第一位置。
16.根据权利要求10所述的外壳组合件，其特征在于，所述推动器和所述刀架中的一个包括可断裂环，并且所述推动器和所述刀架中的另一个包括定位成接合所述可断裂环的环形突起。
17.根据权利要求16所述的外壳组合件，其特征在于，所述可断裂环适于在所述推动器接近其前进位置时断裂，以便于所述刀架独立于所述推动器移动。
18.一种外壳组合件，其包含：
限定空腔的外壳壳体；
支撑在所述外壳壳体上的钉仓，所述钉仓支撑多个缝合钉；
限定纵向孔的推动器，所述推动器能够在所述外壳壳体的所述空腔内从缩回位置移动到前进位置，以从所述钉仓中弹出所述多个缝合钉；
能够在所述推动器的所述纵向孔内移动的刀架；和
支撑在所述刀架上的刀具；
其特征在于，所述刀架可释放地联接到所述推动器上并且能够独立于所述推动器移动以在缝合钉形成之后切割组织。
19.根据权利要求18所述的外壳组合件，其特征在于，所述刀架包括至少一个突片，所述至少一个突片能够从与所述推动器接合以将所述刀架的远端移动转换为所述推动器的远端移动的第一位置移动到允许所述刀架独立于所述推动器向远端前进的第二位置。
20.根据权利要求18所述的外壳组合件，其特征在于，所述推动器和所述刀架中的一个包括可断裂环，并且所述推动器和所述刀架中的另一个包括定位成接合所述可断裂环的环形突起。
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| PCT/CN2019/089545 WO2020237631A1 (en) | 2019-05-31 | 2019-05-31 | Circular stapling device |
| CNPCT/CN2019/089545 | 2019-05-31 |
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| CN111566743B (zh) | 2017-12-28 | 2024-01-16 | 爱惜康有限责任公司 | 用于检测端部执行器组织分布不规则性的外科系统 |
| AU2019201032A1 (en) | 2018-03-13 | 2019-10-03 | Covidien Lp | Chip assembly for reusable surgical instruments |
| US10952734B2 (en) * | 2018-04-23 | 2021-03-23 | Covidien Lp | Stapling device with cut ring biasing member |
| CA3139541A1 (en) * | 2019-05-31 | 2020-12-03 | Covidien Lp | Circular stapling device |
| US11911038B2 (en) * | 2020-01-13 | 2024-02-27 | Covidien Lp | Cut optimization for excessive tissue conditions |
-
2019
- 2019-05-31 CA CA3139541A patent/CA3139541A1/en active Pending
- 2019-05-31 US US17/611,396 patent/US11896233B2/en active Active
- 2019-05-31 EP EP19931465.9A patent/EP3975876A4/en active Pending
- 2019-05-31 JP JP2021569883A patent/JP2022543958A/ja not_active Ceased
- 2019-05-31 AU AU2019448247A patent/AU2019448247A1/en active Pending
- 2019-05-31 WO PCT/CN2019/089545 patent/WO2020237631A1/en unknown
-
2020
- 2020-05-27 CN CN202020914464.4U patent/CN214259400U/zh active Active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2020237631A1 (en) | 2020-12-03 |
| US11896233B2 (en) | 2024-02-13 |
| US20220211381A1 (en) | 2022-07-07 |
| CA3139541A1 (en) | 2020-12-03 |
| JP2022543958A (ja) | 2022-10-17 |
| AU2019448247A1 (en) | 2021-12-16 |
| EP3975876A4 (en) | 2023-01-04 |
| EP3975876A1 (en) | 2022-04-06 |
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