SUMMERY OF THE UTILITY MODEL
The utility model aims to overcome the defects of the prior art and provide a platelet-rich plasma separation and collection bag.
The technical scheme adopted by the invention is as follows: a platelet rich plasma separation collection bag comprises a whole blood collection bag, a PRP collection bag and a PPP collection bag. The whole blood collection bag comprises a blood collection inlet. The PRP collecting bag comprises a funnel part and a long pipe part, the funnel part is communicated with the whole blood collecting bag through a first connecting pipe, and a first pipe switch is arranged on the first connecting pipe; the funnel part is also provided with an extraction opening. The PPP collection bag is communicated with the funnel part of the PRP collection bag through a second connecting conduit, and a second conduit switch is arranged on the second connecting conduit.
As the further improvement of the technical scheme, the platelet-rich plasma separation and collection bag further comprises a blood taking needle, wherein the blood taking needle is communicated with the blood taking inlet through a blood transfusion conduit, and a third conduit switch is arranged on the blood transfusion conduit.
As a further improvement of the above technical solution, one end of the first connecting conduit, which is far away from the whole blood collection bag, is connected to the PPP collection bag, that is, the PPP collection bag is disposed between the whole blood collection bag and the PRP collection bag, and the PPP collection bag is communicated with the whole blood collection bag through the first connecting conduit and is simultaneously communicated with the PRP collection bag through the second connecting conduit.
As a further improvement of the above technical solution, one end of the first connecting conduit away from the whole blood collection bag is connected to the funnel portion of the PRP collection bag, that is, the PRP collection bag is directly communicated with the whole blood collection bag through the first connecting conduit, and the PPP collection bag is communicated with the PRP collection bag through the second connecting conduit.
As a further improvement of the technical proposal, the long tube part of the PRP collecting bag is provided with a capacity scale. Specifically, the capacity scale is used for realizing quantitative labeling of the PRP.
As a further improvement of the technical scheme, the PRP collecting bag further comprises a PRP pipe clamp, and the PRP pipe clamp is arranged on the long pipe part of the PRP collecting bag. Specifically, the shape of the PRP pipe clamp is a rectangle, a slit is arranged in the middle of the PRP pipe clamp, and the PRP pipe clamp can divide the content in the long pipe part of the PRP collecting bag into two parts through the slit, so that the quantitative collection of the PRP is realized.
As a further improvement of the above technical solution, the extraction port is further provided with a sealing cover, which keeps the platelet rich plasma separation and collection bag in a sealing state during blood collection and centrifugation.
As a further improvement of the technical scheme, the whole blood collection bag, the PRP collection bag, the PPP collection bag, the first connecting conduit, the second connecting conduit and the blood transfusion conduit are all made of medical PVC materials, so that the whole blood collection bag has medical safety and meets the disposable use requirement of the platelet-rich plasma separation collection bag.
As a further improvement of the above technical means, the whole blood collection bag is divided into an upper portion and a lower portion, an inner diameter of the upper portion is smaller than an inner diameter of the lower portion, and the first connecting conduit communicates with the upper portion of the whole blood collection bag. Particularly, the special shape of the whole blood collection bag can effectively improve the stability of the whole blood collection bag during the first centrifugal operation.
As a further improvement of the above technical solution, the first, second and third conduit switches may be provided as pipe clamps or valves.
The utility model has the advantages that: the utility model discloses a separation that the triplex bag method carried out whole blood plasma and the collection of rich platelet plasma, it is applicable to the twice centrifugal operation who goes on in succession to realized that rich platelet plasma separates to gather and shifts in airtight antithetical couplet bag system, fungible structure complicacy, with high costs and complex operation's PRP separator is applicable to the disposable separation and the collection of the rich platelet plasma that require big to the preparation volume.
Detailed Description
Reference will now be made in detail to embodiments of the present invention, examples of which are illustrated in the accompanying drawings, wherein like reference numerals refer to the same or similar elements or elements having the same or similar function throughout. The embodiments described below with reference to the drawings are exemplary only for the purpose of explaining the present invention, and should not be construed as limiting the present invention.
In the description of the present invention, it should be understood that the orientation or positional relationship indicated with respect to the orientation description, such as up, down, front, rear, left, right, etc., is based on the orientation or positional relationship shown in the drawings, and is only for convenience of description and simplification of description, and does not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus, should not be construed as limiting the present invention.
In the description of the present invention, a plurality of means are one or more, a plurality of means are two or more, and the terms greater than, less than, exceeding, etc. are understood as not including the number, and the terms greater than, less than, within, etc. are understood as including the number. If the first and second are described for the purpose of distinguishing technical features, they are not to be understood as indicating or implying relative importance or implicitly indicating the number of technical features indicated or implicitly indicating the precedence of the technical features indicated.
In the description of the present invention, unless there is an explicit limitation, the words such as setting, installation, connection, etc. should be understood in a broad sense, and those skilled in the art can reasonably determine the specific meanings of the above words in combination with the specific contents of the technical solution.
Example 1
Referring to fig. 1 to 3, a platelet rich plasma separation collection bag includes a whole blood collection bag 100, a PRP collection bag 300, and a PPP collection bag 310.
The PRP collection bag 300 includes a funnel portion and a long tube portion, the funnel portion and the long tube portion are communicated with each other, and the inner diameter of the long tube portion is smaller than that of the funnel portion, that is, the sectional screenshot forming the PRP collection bag 310 is a special-shaped structure formed by splicing a lower test tube-shaped portion and an upper funnel-shaped portion. The long tube portion of the PRP collection bag 300 is further provided with a volume scale 301 and a PRP tube clip 302, wherein the volume scale 301 belongs to the label printing provided on the long tube portion of the PRP collection bag 300, and the PRP tube clip 302 belongs to the external kit for separating the contents in the long tube portion of the PRP collection bag 300. The utility model discloses this PRP collection bag 310's special design has utilized the special shape of its long tube portion, capacity scale 301 and PRP pipe clamp 302's combined action to realize PRP's quantitative collection behind the centrifugal operation of the second time.
In this embodiment, the first connecting conduit 110 is not directly connected to the funnel of the PRP collection bag 300, and specifically, the end of the first connecting conduit 110 away from the whole blood collection bag 100 is directly connected to the PPP collection bag 310, that is, the PPP collection bag 310 is disposed between the whole blood collection bag 100 and the PRP collection bag 300, and the PPP collection bag 310 is connected to the whole blood collection bag 100 through the first connecting conduit 110 and is simultaneously connected to the PRP collection bag 300 through the second connecting conduit 320. And the first connecting conduit 110 and the second connecting conduit 320 may be located on the same side, adjacent side, or opposite side of the PPP collection bag 310. The second conduit switch 330 is disposed on the second connecting conduit 320, and functions to regulate the opening and stopping of the second connecting conduit 320. The extraction port 340 is provided on the funnel of the PRP collection bag 300 for taking out the PRP resulting from the final collection of the separation. The drawing port 340 is further provided with a sealing cover 341 which enables the platelet rich plasma separation and collection bag to maintain a sealed state during blood collection and centrifugation.
In the present embodiment, since the PPP collection bag 310 is not used as a content container in the centrifugation operation, the PPP collection bag may be shaped into a common collection bag shape such as a square or a rectangle.
In this embodiment, the whole blood collection bag 100 is divided into upper and lower parts, the inner diameter on upper part is less than the inner diameter on lower part, first connecting conduit 110 with the upper portion intercommunication of whole blood collection bag 100 forms the design that whole blood collection bag 100 bottom width becomes and diminishes to first connecting conduit 110 kneck width promptly, and it has effectively improved the stability that whole blood collection bag 100 placed when first centrifugal operation, also can guarantee simultaneously after first centrifugal operation, can obtain red blood cell layer and blood plasma layer at the first centrifugation product on whole blood collection bag 100 upper portion in whole blood collection bag 100 lower part to realize follow-up export required blood plasma layer by first connecting conduit 110. The whole blood collection bag 100 further includes a blood collection inlet communicated with the blood collection needle 200 through a blood transfusion tube 210. Meanwhile, a third tube switch 220 is disposed on the blood transfusion tube 210, and is used for regulating and controlling the opening and the stopping of the blood transfusion tube 210.
In this embodiment, the whole blood collection bag 100, the PRP collection bag 300, the PPP collection bag 310, the first connection tube 110, the second connection tube 320, and the blood transfusion tube 210 are all made of medical PVC material, which has medical safety and meets the requirement of disposable platelet-rich plasma separation collection bag.
The PRP separation and collection is carried out by using the platelet rich plasma separation and collection bag of the embodiment, which comprises the following operation steps:
1) opening the third conduit switch 220, collecting a certain amount of whole blood through the lancet 200 into the whole blood collection bag 100 containing anticoagulant, closing the third conduit switch 220 and separating the lancet 200 by means of high-frequency heat sealing;
2) placing the whole blood collection bag 100, the PRP collection bag 300 and the PPP collection bag 310 into a centrifuge together for a first centrifugation operation, and obtaining a centrifugation product with a red blood cell layer below and a blood plasma layer above after the first centrifugation;
3) opening the first conduit switch 120 and the second conduit switch 330, squeezing the plasma layer into the PPP collection bag 310 and then into the PRP collection bag 300, re-closing the first conduit switch 120 and the second conduit switch 330, and simultaneously disconnecting the whole blood collection bag 100 in a high-frequency heat sealing manner;
4) placing the PRP collection bag 300 and the PPP collection bag 310 in a centrifuge together for a second centrifugation operation to obtain a PRP and PPP layered centrifugation product after the second centrifugation, wherein the PRP layer is located at a long tube portion of the PRP collection bag 300, for example, the long tube portion is placed at the bottom of a tray of an external centrifuge, and then the PRP collection bag 300 is fixed on the tray by using an external fixing mechanism (such as a clip and a positioning block);
5) the desired amount of PRP is clamped with the PRP tube clamp 302 according to the volume scale 301, the second conduit switch 330 is opened, the undesired amount of PRP is squeezed into the PPP collection bag 310, the second conduit switch 330 is closed, the PRP tube clamp 302 is removed, and the draw-off port 340 is opened to obtain the desired PRP.
If it is necessary to collect PPP and PRP simultaneously, in step 5), the PRP tube clamp 302 can be used to clamp the layered interface of the second centrifugation product, the second conduit switch 330 is opened, the PPP layer is squeezed into the PPP collection bag 310, the second conduit switch 330 is closed, and the suction port 340 is opened to obtain the desired P RP.
Example 2
Referring to fig. 2 and 4, a platelet rich plasma separation collection bag includes a whole blood collection bag 100, a PRP collection bag 300, and a PPP collection bag 310. The whole blood collection bag 100 has the same structure as in example 1.
The PRP collection bag 300 includes a funnel portion and a long tube portion, the funnel portion and the long tube portion are communicated with each other, and the inner diameter of the long tube portion is smaller than that of the funnel portion, that is, the sectional screenshot forming the PRP collection bag 310 is a special-shaped structure formed by splicing a lower test tube-shaped portion and an upper funnel-shaped portion. The long tube portion of the PRP collection bag 300 is further provided with a volume scale 301 and a PRP tube clip 302, wherein the volume scale 301 belongs to the label printing provided on the long tube portion of the PRP collection bag 300, and the PRP tube clip 302 belongs to the external kit for separating the contents in the long tube portion of the PRP collection bag 300. The utility model discloses this PRP collection bag 310's special design has utilized the special shape of its long tube portion, capacity scale 301 and PRP pipe clamp 302's combined action to realize PRP's quantitative collection behind the centrifugal operation of the second time.
In this embodiment, the first connecting conduit 110 is in direct communication with the funnel portion of the PRP collection bag 300, i.e., the funnel portion of the PRP collection bag 300 is in direct communication with the whole blood collection bag 100 via the first connecting conduit 110, and is in communication with the PPP collection bag 310 via the second connecting conduit 320. The second conduit switch 330 is disposed on the second connecting conduit 320, and functions to regulate the opening and stopping of the second connecting conduit 320. The extraction port 340 is provided on the funnel of the PRP collection bag 300 for taking out the PRP resulting from the final collection of the separation. The drawing port 340 is further provided with a sealing cover 341 which enables the platelet rich plasma separation and collection bag to maintain a sealed state during blood collection and centrifugation.
In the present embodiment, since the PPP collection bag 310 is not used as a content container in the centrifugation operation, the PPP collection bag may be shaped into a common collection bag shape such as a square or a rectangle.
In this embodiment, the whole blood collection bag 100, the PRP collection bag 300, the PPP collection bag 310, the first connection tube 110, the second connection tube 320, and the blood transfusion tube 210 are all made of medical PVC material, which has medical safety and meets the requirement of disposable platelet-rich plasma separation collection bag.
The PRP separation and collection is carried out by using the platelet rich plasma separation and collection bag of the embodiment, which comprises the following operation steps:
1) opening the third conduit switch 220, collecting a certain amount of whole blood through the lancet 200 into the whole blood collection bag 100 containing anticoagulant, closing the third conduit switch 220 and separating the lancet 200 by means of high-frequency heat sealing;
2) placing the whole blood collection bag 100, the PRP collection bag 300 and the PPP collection bag 310 into a centrifuge together for a first centrifugation operation, and obtaining a centrifugation product with a red blood cell layer below and a blood plasma layer above after the first centrifugation;
3) opening the first conduit switch 120, squeezing the plasma layer into the PRP collection bag 300, re-closing the first conduit switch 120, and simultaneously disconnecting the whole blood collection bag 100 by high frequency heat sealing;
4) placing the PRP collection bag 300 and the PPP collection bag 310 in a centrifuge together for a second centrifugation operation to obtain a PRP and PPP layered centrifugation product after the second centrifugation, wherein the PRP layer is required to be ensured to be located at the long tube portion of the PRP collection bag 300, for example, the long tube portion is placed at the bottom of a tray of an external centrifuge, and then the PRP collection bag 300 is fixed on the tray by using an external fixing mechanism (such as a clip and a positioning block);
5) the desired amount of PRP is clamped with the PRP tube clamp 302 according to the volume scale 301, the second conduit switch 330 is opened, the undesired amount of PRP is squeezed into the PPP collection bag 310, the second conduit switch 330 is closed, the PRP tube clamp 302 is removed, and the draw-off port 340 is opened to obtain the desired PRP.
If it is necessary to collect PPP and PRP simultaneously, in step 5), the PRP tube clamp 302 can be used to clamp the layered interface of the second centrifugation product, the second conduit switch 330 is opened, the PPP layer is squeezed into the PPP collection bag 310, the second conduit switch 330 is closed, and the suction port 340 is opened to obtain the desired P RP.
Example 3
Referring to fig. 2 and 5, a platelet rich plasma separation collection bag includes a whole blood collection bag 100, a PRP collection bag 300, and a PPP collection bag 310.
In this embodiment, the structure of the other components is the same as that of embodiment 1 except that the shape of the PPP collection bag 310 is different from that of embodiment 1. Specifically, in this embodiment, the PPP collection bag 310 is configured in the same shape as the whole blood collection bag 100, that is, the PPP collection bag 310 is divided into an upper portion and a lower portion, the inner diameter of the upper portion is smaller than the inner diameter of the lower portion, the first connection conduit 110 and the second connection conduit 320 are respectively communicated with the upper portion of the PPP collection bag 310, that is, the PPP collection bag 310 has a bottom width and a width at the interface of the first connection conduit 110 and the interface of the second connection conduit 320 is reduced.
In this embodiment, the contents are placed in the PPP collection bag 310 during the second centrifugation, so the shape of the PPP collection bag 310 can effectively improve the stability of the PPP collection bag 310 during the second centrifugation, and ensure that the second centrifugation product with the PPP layer at the lower part of the PPP collection bag 310 and the PRP layer at the upper part of the PPP collection bag 310 can be obtained after the second centrifugation, thereby realizing the subsequent output of the required PRP layer from the second connection conduit 320.
The PRP separation and collection is carried out by using the platelet rich plasma separation and collection bag of the embodiment, which comprises the following operation steps:
1) opening the third conduit switch 220, collecting a certain amount of whole blood through the lancet 200 into the whole blood collection bag 100 containing anticoagulant, closing the third conduit switch 220 and separating the lancet 200 by means of high-frequency heat sealing;
2) placing the whole blood collection bag 100, the PRP collection bag 300 and the PPP collection bag 310 into a centrifuge together for a first centrifugation operation, and obtaining a centrifugation product with a red blood cell layer below and a blood plasma layer above after the first centrifugation;
3) opening the first conduit switch 120, squeezing the plasma layer into the PPP collection bag 310, closing the first conduit switch, and simultaneously separating the whole blood collection bag 100 by high-frequency heat sealing;
4) placing the PPP collection bag 310 and the PRP collection bag 300 in a centrifuge together for a second centrifugation operation to obtain a PRP and PPP layered centrifugation product after the second centrifugation, wherein the PRP layer is required to be ensured to be located at the interface of the second connection conduit 320, for example, placing the upper part of the PPP collection bag 310 at the bottom of a tray of an external centrifuge, and then fixing the PPP collection bag 310 on the tray by using an external fixing mechanism (such as a clip and a positioning block);
5) opening the second conduit switch 330 to allow the PRP layer to flow into the PRP collecting bag 300, and closing the second conduit switch 330 by controlling the PRP inflow according to the volume scale 301 on the proboscis portion of the PRP collecting bag 300;
6) the extraction port 340 is opened to obtain the desired PRP.
The embodiments of the present invention have been described in detail with reference to the accompanying drawings, but the present invention is not limited to the above embodiments, and various changes can be made without departing from the spirit of the present invention within the knowledge of those skilled in the art.