CN213884485U - Blood purification system with blood waste adsorption function - Google Patents
Blood purification system with blood waste adsorption function Download PDFInfo
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- CN213884485U CN213884485U CN202022476267.1U CN202022476267U CN213884485U CN 213884485 U CN213884485 U CN 213884485U CN 202022476267 U CN202022476267 U CN 202022476267U CN 213884485 U CN213884485 U CN 213884485U
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- Prior art keywords
- blood
- ultrafiltration
- output
- waste liquid
- adsorber
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- 239000008280 blood Substances 0.000 title claims abstract description 73
- 210000004369 blood Anatomy 0.000 title claims abstract description 70
- 239000002699 waste material Substances 0.000 title claims abstract description 37
- 238000000746 purification Methods 0.000 title claims abstract description 27
- 238000001179 sorption measurement Methods 0.000 title claims description 19
- 238000000108 ultra-filtration Methods 0.000 claims abstract description 35
- 239000007788 liquid Substances 0.000 claims abstract description 23
- 230000000694 effects Effects 0.000 claims abstract description 21
- 239000002086 nanomaterial Substances 0.000 claims abstract description 21
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 7
- 239000000463 material Substances 0.000 claims abstract description 6
- 239000006096 absorbing agent Substances 0.000 claims description 18
- 238000002156 mixing Methods 0.000 claims description 11
- 239000012528 membrane Substances 0.000 claims description 5
- 239000003053 toxin Substances 0.000 abstract description 10
- 231100000765 toxin Toxicity 0.000 abstract description 10
- 229920000642 polymer Polymers 0.000 abstract description 5
- 238000001914 filtration Methods 0.000 abstract description 3
- 238000010521 absorption reaction Methods 0.000 abstract 1
- 239000003814 drug Substances 0.000 description 17
- DDRJAANPRJIHGJ-UHFFFAOYSA-N creatinine Chemical compound CN1CC(=O)NC1=N DDRJAANPRJIHGJ-UHFFFAOYSA-N 0.000 description 10
- 239000000654 additive Substances 0.000 description 8
- 238000001631 haemodialysis Methods 0.000 description 8
- 230000000322 hemodialysis Effects 0.000 description 8
- 108700012359 toxins Proteins 0.000 description 8
- 238000000502 dialysis Methods 0.000 description 7
- 238000000034 method Methods 0.000 description 6
- 230000000996 additive effect Effects 0.000 description 5
- 229940109239 creatinine Drugs 0.000 description 5
- 239000004372 Polyvinyl alcohol Substances 0.000 description 3
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 3
- 239000004202 carbamide Substances 0.000 description 3
- 150000002500 ions Chemical class 0.000 description 3
- 229920002451 polyvinyl alcohol Polymers 0.000 description 3
- 230000008929 regeneration Effects 0.000 description 3
- 238000011069 regeneration method Methods 0.000 description 3
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 2
- 229920000049 Carbon (fiber) Polymers 0.000 description 2
- PNNCWTXUWKENPE-UHFFFAOYSA-N [N].NC(N)=O Chemical compound [N].NC(N)=O PNNCWTXUWKENPE-UHFFFAOYSA-N 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 239000002861 polymer material Substances 0.000 description 2
- 239000000758 substrate Substances 0.000 description 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 208000001647 Renal Insufficiency Diseases 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 239000004917 carbon fiber Substances 0.000 description 1
- 239000012876 carrier material Substances 0.000 description 1
- 150000001768 cations Chemical class 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 201000006370 kidney failure Diseases 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 239000004005 microsphere Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 229920000728 polyester Polymers 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000001846 repelling effect Effects 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 150000003384 small molecules Chemical class 0.000 description 1
- 238000002798 spectrophotometry method Methods 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 238000002054 transplantation Methods 0.000 description 1
- 229920003169 water-soluble polymer Polymers 0.000 description 1
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Abstract
The utility model discloses a blood purification system with blood waste absorption as purpose. The input end of an ultrafiltration pump in the system is connected with a human body through a blood input pipeline, the output water of the ultrafiltration pump is connected with an ultrafiltration waste liquid collector, the output blood of the ultrafiltration pump is connected with a dosing mixed adsorber, the input end of the dosing mixed adsorber is also connected with a nano material adder, the waste liquid output end of the dosing mixed adsorber is connected with the waste liquid collector, the blood output end of the dosing mixed adsorber is connected with a purification effect detector, and the output end of the purification effect detector is connected with a blood output pipeline. The utility model discloses utilize nano-material's characteristic, and the collection of toxin molecule in the blood, form the polymer, utilize the adsorbing material to filter the polymer that forms once more to reach the mesh of thoroughly cleaing away toxin, effective components such as human required micromolecule can not filtered simultaneously. The water quantity needing ultrafiltration is accurately controlled through the ultrafiltration pump. It is simple and convenient to operate and has good filtering effect.
Description
Technical Field
The utility model relates to the technical field of medical equipment, especially, relate to a blood purification system with adsorb blood wastes material as purpose.
Background
Since dialysis was developed, uremic patients have become available for long-term survival. Adequate hemodialysis treatment of end-stage renal patients can reduce morbidity and mortality of complications. Adequacy of hemodialysis refers to the amount of dialysis given with morbidity and mortality associated with dialysis minimized, and is referred to as optimal dialysis or adequacy of dialysis. The currently effective treatment means for patients with renal failure before kidney transplantation is a hemodialysis method, and when the treatment method is used for treatment, the patients need to go to a hospital to use a hemodialysis machine and accessories matched with the hemodialysis machine to effectively treat the patients. The treatment method of the existing hemodialysis machine is effective, but causes great inconvenience to the work and life of patients.
A portable dialysate regeneration system for human dialysis, which is applied by Kemca technology Limited in the United states at present, has a Chinese application patent number of 200480038117.3 and an authorized publication number of CN 1897993B. The key technology of the patent is to adopt a dialysate regeneration chamber, namely a toxin interceptor capable of selectively intercepting toxins and repelling selective cations, wherein the described toxin interceptor comprises ion-selective urease-immobilized activated carbon fibers with ion-selective barriers.
Although the above method can remove creatinine and urea nitrogen in blood, the operation process and effect are not optimal, and therefore, it is important to provide a system that can remove creatinine and urea nitrogen without destroying other components in blood.
SUMMERY OF THE UTILITY MODEL
In view of the above-mentioned defects in the prior art, the technical problem to be solved in the present invention is to provide a blood purification system aiming at adsorbing blood wastes, so as to solve the deficiencies in the prior art.
In order to realize the above object, the utility model provides an use blood purification system who adsorbs blood waste as purpose, including the ultrafiltration pump, add medicine hybrid absorber, nano-material adder, waste liquid collector, ultrafiltration waste liquid collector and purifying effect detector, the ultrafiltration pump input passes through blood input tube coupling human body, ultrafiltration pump output moisture connects ultrafiltration waste liquid collector all the way, the connection of ultrafiltration pump output blood all the way adds medicine hybrid absorber, add the medicine hybrid absorber input and still connect the nano-material adder, add the waste liquid output of medicine hybrid absorber and connect the waste liquid collector, add the blood output of medicine hybrid absorber and connect the purifying effect detector, purifying effect detector output connects blood output pipeline.
Further, it contains the casing, adds medicine hybrid chamber, pellicle and adsorption cavity to add medicine hybrid absorber, add the pellicle between medicine hybrid chamber, the adsorption cavity.
Furthermore, one path of the blood output by the ultrafiltration pump is connected with the dosing mixed adsorber through a blood purification input pipeline.
Furthermore, the input end of the dosing mixing cavity of the dosing mixing adsorber is connected with a nano-material adder.
Further, the adsorption cavity contains an adsorption material.
The utility model has the advantages that:
the utility model discloses a nano-material adder adds the nano-additive in adding medicine hybrid absorber, utilizes the characteristic of nano-material, and the toxin molecule set in the blood, forms the polymer, and the adsorption material that adds in the medicine hybrid absorber of utilizing filters the polymer that forms once more to reach the mesh of thoroughly clearing away toxin, effective components such as human required micromolecule can not filtered simultaneously. The water quantity needing ultrafiltration is accurately controlled through the ultrafiltration pump. It is simple and convenient to operate and has good filtering effect.
The conception, the specific structure and the technical effects of the present invention will be further described with reference to the accompanying drawings, so as to fully understand the objects, the features and the effects of the present invention.
Drawings
Fig. 1 is a schematic flow diagram of a dialysate regeneration system for portable human dialysis (chinese patent publication No. CN 1897993B).
Fig. 2 is a schematic structural diagram of a blood purification system for the purpose of adsorbing blood waste according to the present invention.
In fig. 2: 1-blood input line; 2-an ultrafiltration pump; 3-adding a medicine mixing adsorber; 3-1-adding medicine mixing cavity; 3-2-adsorption cavity; 4-nanomaterial addition device; 5-a waste liquid collector; 6-ultrafiltration waste liquid collector; 7-blood purification input line; 8-blood output line; 9-purification effect detector.
Detailed Description
As shown in figure 2, a blood purification system with blood waste adsorption as the purpose, including ultrafiltration pump 2, add medicine mixed adsorber 3, nano-material adder 4, waste liquid collector 5, ultrafiltration waste liquid collector 6 and purifying effect detector 9, the human body is connected through blood input pipeline 1 to ultrafiltration pump 2 input, ultrafiltration waste liquid collector 6 is connected all the way of ultrafiltration pump 2 output moisture, it adds medicine mixed adsorber 3 to connect all the way of ultrafiltration pump 2 output blood, add medicine mixed adsorber 3 input and still connect nano-material adder 4, waste liquid collector 5 is connected to the waste liquid output of medicine mixed adsorber 3, purifying effect detector 9 is connected to the blood output of medicine mixed adsorber 3, purifying effect detector 9 output connects blood output pipeline 8. Wherein, the ultrafiltration pump 5 carries out accurate control to the water yield of cleaing away as required, and purification effect detector 9 carries out blood detection according to the spectrophotometry principle.
Wherein, the drug-adding mixed absorber 3 comprises a shell, a drug-adding mixed cavity 3-1, a semi-permeable membrane and an adsorption cavity 3-2, and the semi-permeable membrane is arranged between the drug-adding mixed cavity 3-1 and the adsorption cavity 3-2. One path of the blood output by the ultrafiltration pump 2 is connected with the medicine-adding mixed absorber 3 through a blood purification input pipeline 7. The input end of a dosing mixing cavity 3-1 of the dosing mixing adsorber 3 is connected with a nano material adder 4, and an adsorption cavity 3-2 of the dosing mixing adsorber 3 contains adsorption materials, mainly composites of polyester fibers and carbon fibers, and is used for removing creatinine and urea after the polymers are synthesized.
The utility model discloses a theory of operation is: blood in the human body is input into the ultrafiltration pump 2 through the blood input pipeline 1 to carry out water outlet operation on the blood, water which is ultrafiltered through the ultrafiltration pump 2 is conveyed to the ultrafiltration waste liquid collector 6, the blood which is ultrafiltered enters the dosing mixed adsorber 3 through the blood purification input pipeline 7, meanwhile, the nano-additive is injected into the dosing mixed adsorber 3 by the nano-material adder 4, the blood which is treated by the dosing mixed adsorber 3 and detected by the purification effect detector 9 is back-transfused to the human body through the blood output pipeline 8 to complete the blood purification process, and simultaneously, the participation liquid of redundant nano-additive is recovered through the waste liquid collector 5.
Wherein, the nano material adder 4 injects nano additive into the drug-adding mixing cavity 3-1 of the drug-adding mixing adsorber 3 to mix with the input blood, then the blood added with nano additive passes through the semipermeable membrane and then is input into the filter cavity to be filtered, and the filtered toxin is retained in the adsorption cavity 3-2. The added nano additive is added with small molecules and glucose which are required to be finished through diffusion.
The added nano additive comprises a nano material as a substrate, and crosslinked polyvinyl alcohol microspheres (CPVA) formed by polyvinyl alcohol PVA are added on the substrate, and the added nano additive is a water-soluble polymer with biocompatibility as a biocompatible carrier material, can form a polymer material or a polymer material with the functions of adsorbing creatinine, urea and other toxins, and is used for adsorbing creatinine, adsorbing urea, and adjusting the ion concentration and acid-base balance in blood.
To sum up, the utility model designs a new hemodialysis purifier, thoroughly clear away unnecessary moisture in the blood earlier, then through adding adsorbability nano-material to blood, enlarge the back with the toxin molecule, through filter equipment, remain the discarded object in the filter, and pass through effectual blood filter, final clean blood is carried and can be human. The nano material is added into the filtering device, the waste in the blood is adsorbed and fixed by utilizing the adsorption effect of the nano material, the purified blood is then transfused into the human body, and the purifier with the waste can be discarded after being used. The utility model discloses an add nano-material's auxiliary device, simplify the dislysate that the hemodialysis in-process needs, be applicable to and operate in different occasions, the user does not influence work and social activity.
The foregoing has described in detail preferred embodiments of the present invention. It should be understood that numerous modifications and variations can be devised by those skilled in the art in light of the present teachings without departing from the inventive concepts. Therefore, the technical solutions that can be obtained by a person skilled in the art through logic analysis, reasoning or limited experiments based on the prior art according to the concepts of the present invention should be within the scope of protection defined by the claims.
Claims (5)
1. A blood purification system for the purpose of adsorbing blood waste, characterized in that: comprises an ultrafiltration pump (2), a drug-adding mixed absorber (3), a nano-material adder (4), a waste liquid collector (5), an ultrafiltration waste liquid collector (6) and a purification effect detector (9), the input end of the ultrafiltration pump (2) is connected with a human body through a blood input pipeline (1), one path of the water output by the ultrafiltration pump (2) is connected with an ultrafiltration waste liquid collector (6), one path of the blood output by the ultrafiltration pump (2) is connected with a medicine-adding mixed absorber (3), the input end of the drug-adding mixed absorber (3) is also connected with a nano-material adder (4), the waste liquid output end of the dosing mixed absorber (3) is connected with a waste liquid collector (5), the blood output end of the drug-adding mixed absorber (3) is connected with a purification effect detector (9), the output end of the purification effect detector (9) is connected with the blood output pipeline (8).
2. A blood purification system for the purpose of adsorbing blood waste products as claimed in claim 1, wherein: the medicine-adding mixed absorber (3) comprises a shell, a medicine-adding mixed cavity (3-1), a semi-permeable membrane and an adsorption cavity (3-2), wherein the semi-permeable membrane is arranged between the medicine-adding mixed cavity (3-1) and the adsorption cavity (3-2).
3. A blood purification system for the purpose of adsorbing blood waste products as claimed in claim 1, wherein: one path of the blood output by the ultrafiltration pump (2) is connected with the medicine-adding mixed absorber (3) through a blood purification input pipeline (7).
4. A blood purification system for the purpose of adsorbing blood waste products as claimed in claim 1, wherein: the input end of a dosing mixing cavity (3-1) of the dosing mixing absorber (3) is connected with a nano material adder (4).
5. A blood purification system for the purpose of adsorbing blood waste as set forth in claim 2, wherein: the adsorption cavity (3-2) contains an adsorption material.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202022476267.1U CN213884485U (en) | 2020-10-31 | 2020-10-31 | Blood purification system with blood waste adsorption function |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202022476267.1U CN213884485U (en) | 2020-10-31 | 2020-10-31 | Blood purification system with blood waste adsorption function |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN213884485U true CN213884485U (en) | 2021-08-06 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202022476267.1U Expired - Fee Related CN213884485U (en) | 2020-10-31 | 2020-10-31 | Blood purification system with blood waste adsorption function |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN213884485U (en) |
-
2020
- 2020-10-31 CN CN202022476267.1U patent/CN213884485U/en not_active Expired - Fee Related
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| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20210806 |
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| CF01 | Termination of patent right due to non-payment of annual fee |