CN213866139U

CN213866139U - PCR nucleic acid amplification instrument

Info

Publication number: CN213866139U
Application number: CN202022289718.0U
Authority: CN
Inventors: 宋泽文
Original assignee: Shenzhen Shengze Chuangxin Technology Co ltd
Current assignee: Shenzhen Shengze Chuangxin Technology Co ltd
Priority date: 2020-10-14
Filing date: 2020-10-14
Publication date: 2021-08-03
Anticipated expiration: 2030-10-14

Abstract

The utility model discloses a PCR nucleic acid amplification instrument, which comprises a shell, a detection probe, a PCB, a fixed tube, a test tube for containing reaction liquid and a cylinder for controlling the test tube to move up and down; fixed pipe is established in the shell, and fixed pipe is equipped with the accommodation hole that holds the test tube along the axis direction, and the lateral wall of fixed pipe runs through at least that there is a through-hole that communicates with the accommodation hole, the directional through-hole of test probe, and test probe is connected with the PCB board, and the test tube setting just can follow the accommodation hole and reciprocate in the accommodation hole. The integrated equipment can complete the whole process from nucleic acid amplification to final detection, can reduce the operation steps from nucleic acid amplification to detection, and reduce the errors caused by artificial operation, such as complicated operation process, multiple reaction steps, long reaction time and the like caused by excessive operation steps; the relative position of the test tube and the detection probe can be adjusted, so that the detection probe can accurately acquire the reaction process in the test tube.

Description

PCR nucleic acid amplification instrument

Technical Field

The utility model relates to a PCR nucleic acid amplification appearance.

Background

At present, the digital PCR equipment and the detection mode in the market are split, and the final detection can be completed only by carrying out different steps on the split equipment. This is a digital PCR device with some disadvantages: because the step-by-step machine operation is complex and time-consuming, errors in the operation process are easily caused, and the final result is inaccurate.

SUMMERY OF THE UTILITY MODEL

The utility model aims to solve the defects of the prior art and provide a PCR nucleic acid amplification instrument.

The utility model discloses a technical scheme:

a PCR nucleic acid amplification instrument comprises a shell, a detection probe, a PCB, a fixed tube, a test tube for containing reaction liquid and an air cylinder for controlling the test tube to move up and down; the utility model discloses a test tube, including fixed pipe, the lateral wall of fixed pipe, fixed pipe is equipped with the accommodation hole that holds the test tube along the axis direction, the lateral wall of fixed pipe at least runs through have a through-hole that communicates with the accommodation hole, the directional through-hole of test probe, test probe is connected with the PCB board, the test tube sets up and reciprocates in the accommodation hole and can follow the accommodation hole.

A preferable scheme is that a liquid adding container is fixed at the top of the test tube and is communicated with the test tube.

The PCR nucleic acid amplification instrument preferably further comprises a slide rail and a slide block sliding along the slide rail, the liquid adding container is fixedly connected with the slide block, a lifting shaft of the air cylinder is connected with the slide block, and the air cylinder controls the slide block to slide up and down along the slide rail.

One preferred scheme is that the number of the through holes is 2 to 10, the number of the detection probes is 2 to 10, and the detection probes are arranged at intervals.

The air flow channel is formed between the detection probe and the inner wall of the shell, an air outlet is formed in one side wall of the shell, a fan is arranged at the air outlet, an air inlet is formed in the other side wall of the shell, and the air inlet, the air flow channel and the air outlet are communicated.

A preferred scheme is that the shell is provided with a display screen, and the display screen is connected with the PCB.

A preferable scheme is that the top of the shell is provided with a liquid filling port, and the liquid filling port is rotatably provided with a rotating cover.

Synthesize above-mentioned technical scheme, the beneficial effects of the utility model: the utility model is an integrated device, which can complete the whole process from nucleic acid amplification to final detection, and can reduce the operation steps from nucleic acid amplification to detection, reduce the operation process complexity, reaction steps, reaction time and errors caused by manual operation due to excessive operation steps; the cylinder can drive the test tube and reciprocate along the accommodation hole to the relative position of adjustment test tube and test probe makes test probe can accurately gather the reaction process in the test tube.

The foregoing description is only an overview of the technical solutions of the present invention, and in order to make the technical means of the present invention more clearly understood, the present invention may be implemented according to the content of the description, and in order to make the above and other objects, features, and advantages of the present invention more obvious and understandable, the following preferred embodiments are described in detail with reference to the accompanying drawings.

Drawings

Fig. 1 is a perspective view of the present invention;

fig. 2 is an exploded view of the present invention;

FIG. 3 is an internal perspective view of the present invention;

FIG. 4 is a partial perspective view of the interior of the present invention;

FIG. 5 is a partial perspective view of the inside of the present invention;

FIG. 6 is a perspective view of the fixing tube of the present invention;

fig. 7 is a perspective view of the middle housing of the present invention.

Detailed Description

For the purpose of illustrating the spirit and purposes of the present invention, the present invention will be further described with reference to the accompanying drawings and specific embodiments.

As shown in fig. 1 to 7, a PCR nucleic acid amplification apparatus includes a housing 10, a detection probe 20, a PCB 30, a fixing tube 40, a test tube 50 for containing a reaction liquid, and a cylinder 60 for controlling the up and down movement of the test tube 50; fixed pipe 40 is established in shell 10, fixed pipe 40 is equipped with the accommodation hole 41 that holds test tube 50 along the axis direction, the lateral wall of fixed pipe 40 at least runs through one through-hole 42 that communicates with accommodation hole 41, the directional through-hole 42 of test probe 20, test probe 20 is connected with PCB board 30, test tube 50 sets up and just can reciprocate along accommodation hole 41 in accommodation hole 41.

As shown in fig. 1 to 7, a test tube 50 is filled with a liquid to be detected, the test tube 50 is inserted into a fixing tube 40, the detection probe 20 can detect a liquid reaction process and transmit the reaction process to the PCB 30, and the PCB 30 determines that a map showing a certain genetic disease is present in the liquid to be detected. The cylinder 60 can control the test tube 50 to be arranged in the accommodating hole 41 and move up and down along the accommodating hole 41, so as to adjust the position of the test tube 50, and the detection probe 20 can accurately collect the reaction process of the liquid in the test tube 50. The utility model is an integrated equipment, which can complete the whole process from nucleic acid amplification to final detection, and the integrated equipment can reduce the operation steps from nucleic acid amplification to detection, reduce the operation process complexity, reaction steps and reaction time caused by excessive operation steps, and reduce the error caused by manual operation; the cylinder can drive test tube 50 and reciprocate along the accommodation hole to the relative position of adjustment test tube 50 and test probe 20 makes test probe 20 can accurately gather the reaction process in test tube 50.

As shown in fig. 1 to 7, a priming container 51 is fixed to the top of the test tube 50, and the priming container 51 is in communication with the test tube 50. The radius of the liquid adding container 51 is larger than that of the test tube 50 and is communicated with the test tube 50, so that liquid can be conveniently added.

As shown in FIGS. 1 to 7, the PCR nucleic acid amplification apparatus further comprises a slide rail 61, a slide block 62 sliding along the slide rail 61, the feeding container 51 is fixedly connected with the slide block 62, the lifting shaft of the air cylinder 60 is connected with the slide block 62, and the air cylinder 60 controls the slide block 62 to slide up and down along the slide rail 61. Thereby adjusting the position of the test tube 50, so that the reaction process of the liquid in the test tube 50 can be accurately acquired by the detection probe 20.

As shown in fig. 1 to 7, the number of the through holes 42 is 2 to 10, the number of the inspection probes 20 is 2 to 10, and the inspection probes 20 are alternately arranged. The detection probe 20 is provided with a camera therein, and the camera can accurately collect the reaction process in the test tube 50. Each detection probe 20 is relatively fixed, the air cylinder 60 controls the test tube 50 to move up and down along the accommodating hole 41, each detection probe 20 is accurately aligned with the through hole 42 at the corresponding position, and when the test tube 50 moves up and down along the accommodating hole 41 to the corresponding through hole 42, the corresponding detection probe 20 can accurately detect the reaction process of the test tube 50.

As shown in fig. 1 to 7, an airflow channel exists between the detection probe 20 and the inner wall of the housing 10, an air outlet 11 is disposed on one side wall of the housing 10, a fan 12 is disposed at the air outlet 11, an air inlet 13 is disposed on the other side wall of the housing 10, and the air inlet 13, the airflow channel and the air outlet 11 are communicated. The fan 12 can rapidly take out heat in the housing 10 and reduce the temperature in the housing 10.

As shown in fig. 1 to 7, the housing 10 is provided with a display screen 16, and the display screen 16 is connected to a PCB 30. The display screen 16 can reduce the reaction process.

As shown in fig. 1 to 7, a filling opening 14 is opened at the top of the housing 10, and the filling opening 14 is rotatably provided with a rotating cover 15. The rotary cap 15 prevents dust and foreign materials from entering the test tube 50.

The side wall of the shell 10 is also provided with an opening 17, a power supply wiring plug 18 and a switch 19 are arranged in the opening 17, and the power supply wiring plug 18 is connected with the PCB 30.

The above is a detailed implementation manner of the present invention, and it should be noted that, for those skilled in the art, a plurality of improvements and decorations can be made without departing from the principle of the present invention, and these improvements and decorations are also considered as the protection scope of the present invention.

Claims

1. A PCR nucleic acid amplification instrument is characterized by comprising a shell, a detection probe, a PCB (printed circuit board), a fixed tube, a test tube for containing reaction liquid and an air cylinder for controlling the test tube to move up and down; the utility model discloses a test tube, including fixed pipe, the lateral wall of fixed pipe, fixed pipe is equipped with the accommodation hole that holds the test tube along the axis direction, the lateral wall of fixed pipe at least runs through have a through-hole that communicates with the accommodation hole, the directional through-hole of test probe, test probe is connected with the PCB board, the test tube sets up and reciprocates in the accommodation hole and can follow the accommodation hole.

2. The PCR nucleic acid amplification apparatus of claim 1, wherein a priming container is fixed to the top of the cuvette, and the priming container is in communication with the cuvette.

3. The PCR nucleic acid amplification instrument of claim 2, further comprising a slide rail, a slide block sliding along the slide rail, wherein the liquid adding container is fixedly connected with the slide block, the lifting shaft of the cylinder is connected with the slide block, and the cylinder controls the slide block to slide up and down along the slide rail.

4. The PCR nucleic acid amplification apparatus of any one of claims 1 to 3, wherein the number of the through holes is 2 to 10, the number of the detection probes is 2 to 10, and the detection probes are arranged at intervals.

5. The PCR nucleic acid amplification instrument of claim 4, wherein the detection probe and the inner wall of the housing form an airflow channel, one side wall of the housing is provided with an air outlet, the air outlet is provided with a fan, the other side wall of the housing is provided with an air inlet, and the air inlet, the airflow channel and the air outlet are communicated.

6. The PCR nucleic acid amplification apparatus of claim 1, wherein the housing is provided with a display screen, and the display screen is connected with the PCB.

7. The PCR nucleic acid amplification apparatus of claim 1, wherein the top of the housing is provided with a filling opening, and the filling opening is rotatably provided with a rotary cover.