CN213242488U - Ion source with separation and enrichment functions - Google Patents
Ion source with separation and enrichment functions Download PDFInfo
- Publication number
- CN213242488U CN213242488U CN202022100183.8U CN202022100183U CN213242488U CN 213242488 U CN213242488 U CN 213242488U CN 202022100183 U CN202022100183 U CN 202022100183U CN 213242488 U CN213242488 U CN 213242488U
- Authority
- CN
- China
- Prior art keywords
- ion
- sample
- separation
- enrichment
- ions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Images
Landscapes
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
Abstract
The utility model provides an ion source of area separation and enrichment function, including a plurality of cyclic annular electrodes, a plurality of voltage regulation device, atmospheric pressure adjusting device, reaction ion generator and sample conveyor. The ions in the ion migration area are kept balanced under the action of electric field force with the same size but opposite directions and thrust force generated by air pressure difference by adjusting the strength of the electric field and the air pressure, the reaction ions and sample molecules continuously collide to generate sample ions, different sample ions are enriched at different positions in the ion migration area respectively, and after the enrichment reaches the required concentration, the original balance of the sample ions is destroyed by changing the voltage or the air pressure, so that the sample ions are driven to move under the action of unbalanced force in the migration direction and are sequentially conveyed out of the ion migration area. The ion source with the separation and enrichment functions is simple and easy to implement, and the sample ion classification and enrichment are safe and reliable and high in efficiency.
Description
Technical Field
The utility model relates to an ion migration technical field, concretely relates to ion source of area separation and enrichment function.
Background
When a chemical sample is detected by using chemical analysis techniques such as ion mobility spectrometry, mass spectrometry and the like, sample ions need to be conveyed into equipment through an ion mobility tube, the sample ions are generated by an ion source, and the ion source is a device which ionizes neutral atoms or molecules and extracts ion beam current from the neutral atoms or molecules.
When a sample is detected, the concentration of sample ions is an important index influencing the detection precision, and when the concentration of the sample ions generated in a sample unit time is extremely low, the concentration of the sample ions needs to be enriched so as to improve the concentration of the sample ions; the sample ions are ionized to generate different types of sample ions, and the sample ions for detection are mixed, wherein during enrichment, all types of sample ions are generally stored and enriched in a concentrated mode without any distinguishing classification, so that the sample ions output by the ion source are mixed ions, and the ions which are not used for detection form interfering ions, so that the detection accuracy is influenced.
SUMMERY OF THE UTILITY MODEL
Therefore, the technical problem to be solved by the present invention is to overcome the problem that the ion source in the prior art cannot separate and output the mixed ions in sequence.
Therefore, the utility model provides an ion source of area separation and enrichment function, include:
a plurality of annular electrodes coaxially and sequentially fixed together; the adjacent two annular electrodes are arranged at intervals in an insulating way; the inner cavities of all the annular electrodes are communicated to form an ion migration area;
the voltage adjusting devices are connected with the annular electrodes in a one-to-one correspondence mode and are suitable for adjusting the voltage on the annular electrodes to form an uneven electric field in the ion migration region;
the air pressure adjusting device is communicated with the ion migration area and is suitable for forming air pressure difference in the ion migration area;
the reactive ion generator is communicated with the ion migration zone and is suitable for generating reactive ions;
and the sample conveying device is communicated with the ion migration area and is suitable for conveying sample molecules.
The voltage regulating device comprises a divider resistor; the voltage dividing resistors are connected with the corresponding annular electrodes in series; the adjacent divider resistors have different resistance values.
The voltage regulating device also comprises adjustable potentiometers which are in one-to-one correspondence with the divider resistors and are connected in series.
The air pressure regulating device comprises an air pump which is suitable for driving carrier gas carrying a sample to pass through the ion migration area.
The air pressure adjusting device further comprises a flow limiting valve connected with the air pump.
The ring-shaped electrode includes:
four electrode lobes distributed at intervals along the circumferential direction of the ion migration zone;
the insulating block is arranged between two adjacent electrode lobes;
the electrode lobes are suitable for being applied with radio frequency voltage; the radio frequency voltages on adjacent electrode lobes are equal in amplitude and opposite in phase.
Further comprising:
an insulating base having a circular mounting cavity; the electrode flap is fixed within the mounting cavity.
The insulating block is formed on the insulating base.
The reaction ion generator and the sample conveying device are respectively communicated with two ends of the ion migration area.
The utility model discloses technical scheme has following advantage:
1. the utility model provides a take ion source of separation and enrichment function, including a plurality of cyclic annular electrodes, a plurality of voltage regulation device, atmospheric pressure adjusting device, reaction ion generator and sample conveyor. The inner cavities of the annular electrodes are communicated to form an ion migration area, the voltage adjusting device is connected with the corresponding annular electrodes in series and is suitable for adjusting the voltage on the annular electrodes, an uneven electric field is formed in the ion migration area, the electric field intensity from one end of the ion migration area to the other end is gradually enhanced or weakened, ions move under the action of electric field force in the migration area, the air pressure difference in the ion migration area is adjusted through the air pressure adjusting device, the air pressure intensity of one end of the ion migration area to the other end is gradually enhanced or weakened, the ions enter the ion migration area, the ions in the ion migration area are subjected to the same-size but opposite-direction thrust force generated by the air pressure difference to keep balance in the ion migration area through adjusting the strength of the electric field and the strength of the air pressure, and the sample conveying device continuously conveys sample molecules to the ion migration area, meanwhile, the reaction ions generated by the reaction ion generator are continuously conveyed into the ion migration zone, in the ion migration zone, the reaction ions collide with the sample molecules, and the sample molecules are ionized by the charge transfer of the reaction ions to generate the sample ions.
Along with the continuous generation of sample ions, different sample ions are respectively enriched at different positions in the ion migration area, and after the enrichment reaches the required concentration, the original balance of the sample ions is destroyed by changing voltage or air pressure, so that the sample ions are driven to move under the action of unbalanced force in the migration direction and are sequentially separated from the ion migration area. The ion source with the separation and enrichment functions is simple and easy to implement, and the sample ion classification and enrichment are safe and reliable and high in efficiency.
2. The utility model provides a take ion source of separation and enrichment function, cyclic annular electrode includes four electrode lamella, along the circumference interval distribution in ion migration district, set up the insulating block between two adjacent electrode lamella, be suitable for on the electrode lamella to add radiofrequency voltage, radiofrequency voltage's on the adjacent electrode lamella amplitude equals and phase opposite, form the radio frequency electric field in the footpath in ion migration district, receive the effect of radio frequency electric field, sample ion is at central enrichment, avoided sample ion to diffusion all around, the collision cyclic annular electrode inner wall causes the loss.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the embodiments or the technical solutions in the prior art will be briefly described below, and it is obvious that the drawings in the following description are some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to these drawings without creative efforts.
FIG. 1 is a schematic diagram of a ring electrode in an ion source with separation and enrichment functions according to the present invention;
fig. 2 is a schematic partial structure diagram of the ion source with separation and enrichment functions of the present invention.
Description of reference numerals:
1. an insulating base; 2. a ring-shaped electrode; 21. an electrode flap; 22. an insulating block; 3. a front end cover; 4. a rear end cap; 5. an ion transfer region.
Detailed Description
The technical solution of the present invention will be described clearly and completely with reference to the accompanying drawings, and obviously, the described embodiments are some, but not all embodiments of the present invention. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and simplification of description, but do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus, should not be construed as limiting the present invention. Furthermore, the terms "first" and "second" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.
In the description of the present invention, it is to be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "connected," and "connected" are to be construed broadly, and may be, for example, fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present invention can be understood in specific cases to those skilled in the art.
Furthermore, the technical features mentioned in the different embodiments of the invention described below can be combined with each other as long as they do not conflict with each other.
Example 1
The embodiment provides an ion source with separation and enrichment functions, which comprises a plurality of annular electrodes 2, a plurality of voltage adjusting devices, a gas pressure adjusting device, a reaction ion generator and a sample conveying device.
As shown in fig. 1, in this embodiment, the annular electrode 2 is fixed on the insulating base 1, the insulating base 1 has a circular mounting cavity, the annular electrode 2 is fixed in the mounting cavity, in this embodiment, the annular electrode 2 includes four electrode lobes 21, the electrode lobes 21 are conductive metal pieces, the four electrode lobes 21 are distributed at intervals along the circumferential direction of the ion migration region 5, the four electrode lobes 21 together enclose the annular electrode 2 which is annular as a whole, the insulating block 22 is disposed between two adjacent electrode lobes 21, and the four electrode lobes 21 are the same in size and shape and are distributed in central symmetry. The whole insulating base 1 is an annular block, one side wall surface of the annular block is inwards recessed near the central part to form a step-shaped groove, the groove forms an installation cavity for installing the electrode petals 21, the insulating block 22 between every two adjacent electrode petals 21 is formed on the insulating base 1, and the surface of the electrode petals 21 is flush with the surface of the insulating base 1.
As shown in fig. 2, fifteen annular electrodes 2 are disposed in this embodiment, fifteen annular electrodes 2 are coaxially and co-directionally disposed in parallel to form a tubular structure, inner cavities of the annular electrodes 2 are communicated with each other to form an ion migration region 5, a front end cap 3 and a rear end cap 4 are disposed at two ends of the ion migration region 5, and the front end cap 3 and the rear end cap 4 are respectively provided with an input port for communicating reactive ions and sample molecules of the ion migration region 5 and a sample ion output port. For example, in this embodiment, openings are respectively formed in the centers of the front end cap 3 and the rear end cap 4, the reactive ion generator and the sample transport device are both communicated with the ion migration region 5 through the opening in the front end cap 3, and the opening in the rear end cap 4 serves as an output port for sample ions.
In this embodiment, a voltage adjusting device (not shown in the figure) is disposed in one-to-one correspondence with the annular electrodes 2, the voltage adjusting device is a conventional voltage adjusting device, and includes a voltage dividing resistor and an adjustable potentiometer, the voltage dividing resistor is connected in series with the corresponding annular electrode 2, the adjustable potentiometer corresponds to the series voltage dividing resistor, and the resistance of the voltage dividing resistor connected in series with the corresponding annular electrode 2 is adjusted by the adjustable potentiometer, so that the voltages on any two adjacent annular electrodes 2 are different, thereby forming an uneven electric field in the ion migration region 5, sample ions are suitable for moving in the ion migration region 5 under the action of the electric field force, optionally, the adjustable potentiometer is not provided, the resistances of any two adjacent voltage dividing resistors are different, and also different voltages on each annular electrode 2 can be applied. In this embodiment, the voltage on each ring electrode 2 is set to be gradually increased or decreased from the front end toward the rear end of the ion transfer region 5.
The air pressure adjusting device (not shown in the figure) is communicated with the ion migration area 5, the air pressure adjusting device forms gradually reduced or increased air pressure difference at two ends of the ion migration area 5, the carrier gas carries sample ions into the ion migration area 5, and the carrier gas flows from one end with high air pressure to one end with low air pressure in the ion migration area 5 under the action of the air pressure difference. In this embodiment, the air pressure adjusting device is a conventional air pressure adjusting device, and includes an air pump and a flow limiting valve, the air pump communicates with the ion migration zone 5, the air pump may be disposed at the front end or the rear end of the ion migration zone 5, or both ends are disposed, and the flow limiting valve is disposed between the air pump and the ion migration zone 5, so as to adjust the air pressure in the ion migration zone 5. In this embodiment, the front end is an air inlet end, the rear end is an air outlet end, the pressure at the air inlet end is 1-3mbar, the pressure at the air outlet end is about 1mbar, the pressure at the air inlet end is greater than the pressure at the air outlet end, the pressure at the air inlet end is adjusted according to the type of the sample to be detected, and the carrier gas may be nitrogen gas or helium gas. When the pressure intensity of the air inlet end is greater than that of the air outlet end, and at the moment, when the sample ions are positively charged, a gradually increased direct current voltage is applied from the air inlet end to the air outlet end, so that a reverse electric field can be generated, and the electric field force borne by the sample ions is balanced with the gas thrust force, so that the sample ions are kept at a specific position in the ion migration region 5; when the sample ions are negatively charged, a gradually reduced direct current voltage is applied from the gas inlet end to the gas outlet end to generate a reverse electric field, and the electric field force applied to the negatively charged sample ions is equal to the thrust force of the gas and is opposite to the thrust force, so that the sample ions are kept in balance at a specific position in the ion migration zone 5. Along with the sample ions gradually enter the ion migration area 5, the sample gas can be pushed forward, meanwhile, the direct current voltage generates a reverse electric field force, the sample ions reach a balanced state under the action of the electric field force and the pushing force of the air flow, are distributed at different axial positions in the ion migration area 5 according to the mobility of different sample ions, and are enriched at the positions. The collision cross section is smaller, ions with larger mobility are distributed at the front end, the collision cross section is larger, ions with smaller mobility are distributed at the rear end, the potential difference applied to the two ends of the ion migration area 5 is changed, the electric field in the ion migration area 5 can be changed, for positive charges, the electric potential at the front end of the ion migration area 5 is unchanged, and the electric potential at the rear end is reduced, so that the electric field in the ion migration area 5 is integrally reduced, and the sample ions can integrally and gradually move backwards in order to achieve stress balance, so that the ions can be gradually separated from small to large according to the mobility. Or the electric field in the ion migration region 5 is kept unchanged, the pressure at the front end is increased or the pressure at the rear end is weakened, the sample ions can integrally and gradually move backwards to achieve stress balance, and the ions can be gradually separated according to the mobility.
In this embodiment, the radio frequency voltage is applied to the four electrode lobes 21 of each annular electrode 2, the amplitude of the radio frequency voltage on the adjacent electrode lobes 21 is equal and the phase of the radio frequency voltage is opposite, and by adjusting the amplitude and the frequency of the radio frequency voltage, sample ions can be bound in the radial direction, so that the sample ions are prevented from moving in the radial direction of the ion migration region 5 and colliding with the inner wall of the insulating base 1 or the electrode lobes 21 due to the diffusion effect, and the sample ions lose charges and are discharged along with the carrier gas. The concentration and the efficiency of sample ion enrichment are improved.
In this embodiment, a reactive ion generator (not shown in the figure) is disposed at any end of the ion migration region 5 and is communicated with the ion migration region 5, and the generated charged reactive ions enter the ion migration region 5 under the action of an electric field force. The sample conveying device is communicated with the ion migration area 5 through a pipeline, and after carrier gas in the sample conveying device carries sample molecules into the ion migration area 5 and collides with charged reaction ions, the sample molecules are ionized by charge transfer of the reaction ions to generate different sample ions for detection.
The ion source with separation and enrichment functions in this embodiment generates sample ions, and the process of classifying, enriching, and outputting the sample ions in the ion mobility region is as follows:
arranging an electric field with increasing or decreasing intensity in the ion migration region 5 along the migration direction of the ions to form a potential difference; the sample ions are moved by the electric field force F1 in the ion mobility region 5;
forming a pressure difference inside the ion migration zone 5, and subjecting the sample ions to a thrust force F2 in the ion migration zone 5 along with the carrier gas;
the electric force F1 and the thrust F2 are the same in size and opposite in direction;
the reaction ion generator and the sample conveying device continuously convey reaction ions and sample molecules into the ion migration zone, the reaction ions and the sample molecules continuously collide to generate sample ions, and different sample ions are respectively enriched at different positions in the ion migration zone 5 under the interaction of balanced electric field force F1 and thrust force F2.
Radio frequency voltage is added on four electrode lobes of each annular electrode, the amplitude of the radio frequency voltage on the adjacent electrode lobes is equal, the phase of the radio frequency voltage is opposite, and sample ions can be bound in the center of the ion migration region 5 by adjusting the amplitude and the frequency of the radio frequency voltage, so that the sample ions are prevented from diffusing to the periphery.
When the sample ions are classified and enriched for a period of time and reach the required detection concentration, keeping the electric field force F1 unchanged, and changing the magnitude of the pushing force F2; or keeping the pushing force F2 unchanged, and changing the magnitude of the electric field force F1; the sample ions move within the ion transfer region 5 in order to achieve a force balance and are sequentially separated from the ion transfer region 5.
It should be understood that the above examples are only for clarity of illustration and are not intended to limit the embodiments. Other variations and modifications will be apparent to persons skilled in the art in light of the above description. And are neither required nor exhaustive of all embodiments. And obvious variations or modifications can be made without departing from the scope of the invention.
Claims (9)
1. An ion source with separation and enrichment functions, comprising:
a plurality of ring-shaped electrodes (2) which are coaxially and sequentially fixed together; the two adjacent annular electrodes (2) are arranged at intervals in an insulating way; the inner cavities of all the annular electrodes (2) are communicated to form an ion migration area (5);
the voltage adjusting devices are connected with the annular electrodes (2) in a one-to-one correspondence mode and are suitable for adjusting the voltage on the annular electrodes (2) to form an uneven electric field in the ion migration area (5);
the air pressure adjusting device is communicated with the ion migration area (5) and is suitable for forming air pressure difference in the ion migration area (5);
a reactive ion generator, communicating with said ion transfer zone (5), adapted to generate reactive ions;
sample transport means, communicating with said ion transfer region (5), adapted to transport sample molecules.
2. The ion source with separation and enrichment functions of claim 1, wherein the voltage adjustment device comprises a voltage dividing resistor; the voltage dividing resistors are connected with the corresponding annular electrodes (2) in series; the adjacent divider resistors have different resistance values.
3. The ion source with separation and enrichment functions of claim 2, wherein the voltage adjustment device further comprises adjustable potentiometers, which are in one-to-one correspondence with the voltage dividing resistors and are connected in series.
4. The ion source with separation and enrichment functions of claim 1, wherein the gas pressure regulating device comprises a gas pump adapted to drive a carrier gas carrying the sample through the ion transfer region (5).
5. The ion source with separation and enrichment functions of claim 4, wherein the gas pressure regulating device further comprises a flow limiting valve connected to the gas pump.
6. The ion source with separation and enrichment function according to any of claims 1-5, characterized in that the ring-shaped electrode (2) comprises:
four electrode lobes (21) spaced apart along the circumference of the ion transfer region (5);
an insulating block (22) disposed between two adjacent electrode lobes (21);
the electrode lobes (21) are adapted to be impressed with a radio frequency voltage; the radio frequency voltages on adjacent electrode lobes (21) are equal in magnitude and opposite in phase.
7. The ion source with separation and enrichment function of claim 6, further comprising:
an insulating base (1) having a circular mounting cavity; the electrode flap (21) is fixed in the installation cavity.
8. The ion source with separation and enrichment function according to claim 7, characterized in that the insulating block (22) is molded on the insulating base (1).
9. The ion source with separation and enrichment functions of claim 1, wherein the reactive ion generator and the sample conveying device are respectively and communicatively arranged at two ends of the ion migration zone (5).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202022100183.8U CN213242488U (en) | 2020-09-22 | 2020-09-22 | Ion source with separation and enrichment functions |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202022100183.8U CN213242488U (en) | 2020-09-22 | 2020-09-22 | Ion source with separation and enrichment functions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN213242488U true CN213242488U (en) | 2021-05-18 |
Family
ID=75875614
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202022100183.8U Active CN213242488U (en) | 2020-09-22 | 2020-09-22 | Ion source with separation and enrichment functions |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN213242488U (en) |
-
2020
- 2020-09-22 CN CN202022100183.8U patent/CN213242488U/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US6727495B2 (en) | Ion mobility spectrometer with high ion transmission efficiency | |
| CN106575599B (en) | Ion funnel for efficient transport of low mass to charge ratio ions with reduced gas flow at the outlet | |
| US7868289B2 (en) | Mass spectrometer ion guide providing axial field, and method | |
| JP5449777B2 (en) | Ion mobility spectrometer | |
| US6787763B2 (en) | Method and apparatus to increase the resolution and widen the range of differential mobility analyzers (DMAs) | |
| AU739288B2 (en) | Method and device for ion generation | |
| US6251281B1 (en) | Negative ion filter | |
| CA2402798A1 (en) | Faims apparatus and method with ion diverting device | |
| GB1349995A (en) | Particle separators | |
| US2272374A (en) | Device for generating a beam of ions | |
| US20140197333A1 (en) | Mass analyser interface | |
| US20090108195A1 (en) | Apparatus and method for forming a gas composition gradient between faims electrodes | |
| US6100521A (en) | Ion mobility spectrometer in a centripetal arrangement | |
| CN104160474A (en) | Method and apparatus for improved sensitivity in a mass spectrometer | |
| CN1868028B (en) | Ion implanter electrodes | |
| CN213242488U (en) | Ion source with separation and enrichment functions | |
| CN102683151A (en) | Chemical ionization mass spectrometer for selectively controlling reaction ions | |
| EP1532651B1 (en) | Planar flow-by-electrode capacitive electrospray ion source | |
| EP3356026B1 (en) | Plasma reactor for liquid and gas | |
| EP2156461B1 (en) | Detectors and ion sources | |
| CN100514540C (en) | Cycloidal mass spectrometer | |
| Even et al. | Computer optimization for high-resolution time-of-flight mass spectrometer | |
| CN111223748B (en) | Photo-ionization source device for enhancing ion transmission by utilizing charge saturation | |
| CN109841489B (en) | Device for reducing discrimination of transmission quality of radio frequency quadrupole rods | |
| CN116246935A (en) | Ion funnel device for low-mass-to-charge-ratio ion transmission and application method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant |