CN213221038U - Extraction, adsorption and separation device for effective ingredients of traditional Chinese medicine - Google Patents

Abstract

The utility model provides a device for extracting, adsorbing and separating effective components of traditional Chinese medicine, which comprises a raw material tank, wherein the raw material tank is sequentially connected with a filtering unit, a separation and concentration unit and a purification unit; the filtering unit comprises a filtering tank, a primary filtering net and a secondary filtering net are vertically arranged in the filtering tank, a residue port is arranged at the bottom of the filtering tank, and a control valve for controlling residue discharge is arranged on the residue port; the separation and concentration unit comprises a concentration tank, the outer wall of the concentration tank is sleeved with a heating jacket for introducing heating oil, and a plurality of heating plates are arranged in the heating jacket; purification unit includes the chromatography cylinder, the chromatography cylinder is including first cylinder and the second cylinder that from top to bottom sets up, first cylinder with can dismantle the connection between the second cylinder, the chromatography cylinder intussuseption is filled with macroporous resin. The utility model discloses an extract, adsorb, separator carries out the concentration through three continuous operation unit to the active ingredient of traditional chinese medicine and draws.

Description

Extraction, adsorption and separation device for effective ingredients of traditional Chinese medicine

Technical Field

The utility model relates to a traditional chinese medicine draws the purification field, particularly, relates to a traditional chinese medicine active ingredient's extraction, absorption, separator.

Background

The chemical components contained in the traditional Chinese medicine are very complex, and not only contain various effective components, but also have ineffective components and also contain toxic components. Extracting the effective components of the effective monomers, and further separating and purifying the effective components to obtain the effective monomers is an important content in the research field of traditional Chinese medicines. The extraction of the traditional Chinese medicine is to extract the effective components in the traditional Chinese medicine to the maximum extent by utilizing certain technologies, so that the internal quality and the clinical treatment effect of the traditional Chinese medicine preparation are improved, and the effect of the traditional Chinese medicine is exerted to the maximum extent.

In the prior art, in the process of extracting and concentrating the effective components of the traditional Chinese medicine, a concentration tank mode is mostly adopted, and concentration and extraction are carried out according to the characteristic that the boiling points of all components in the traditional Chinese medicine are different, so as to obtain target components, but the operation mode has poor purification effect and insufficient separation, so that the content of the effective components of the final traditional Chinese medicine product cannot achieve ideal effect.

In view of this, the present invention is especially provided.

SUMMERY OF THE UTILITY MODEL

An object of the utility model is to provide a traditional chinese medicine active ingredient draw, adsorb, separator, the device is through setting up filter unit, separation concentration unit and purification unit, and three continuous operation unit carries out the concentration to the active ingredient of traditional chinese medicine and draws, has guaranteed good purification effect, and every unit is for improving concentrated effect moreover, structurally all has carried out optimal design, has solved the poor problem of traditional chinese medicine active ingredient purification effect among the prior art.

In order to realize the above purpose of the utility model, the following technical scheme is adopted:

the utility model provides a device for extracting, adsorbing and separating effective components of traditional Chinese medicine, which comprises a raw material tank, wherein the raw material tank is sequentially connected with a filtering unit, a separation and concentration unit and a purification unit;

the filter unit comprises a filter tank, a primary filter screen and a secondary filter screen are vertically arranged in the filter tank, a residue port is arranged at the bottom of the filter tank, and a control valve for controlling residue discharge is arranged on the residue port;

the separation and concentration unit comprises a concentration tank, the outer wall of the concentration tank is sleeved with a heating jacket for introducing heating oil, and a plurality of heating plates are arranged in the heating jacket;

purification unit includes the chromatography cylinder, the chromatography cylinder is including first cylinder and the second cylinder that from top to bottom sets up, first cylinder with can dismantle the connection between the second cylinder, the chromatography cylinder intussuseption is filled with macroporous resin.

The utility model discloses an extract, adsorb, separator through setting up filter unit, separation concentration unit and purification unit, three continuous operation unit carries out the concentration to the active ingredient of traditional chinese medicine and draws, has guaranteed good purification effect, and every unit is for improving concentrated effect moreover, structurally all carries out optimal design, has solved the poor problem of traditional chinese medicine active ingredient purification effect among the prior art.

The utility model discloses an among the purification unit, through the mutual detachable chromatography cylinder that sets up, simplified the operation, wash more easily, avoided overall structure to bring the inconvenient problem of dismantlement and taken place. Through the peristaltic pump who sets up, can make the appearance liquid of going up advance kind with discontinuous form, increased the dwell time of feed liquid in post inside, effectively promoted separation and purification effect.

Drawings

Various other advantages and benefits will become apparent to those of ordinary skill in the art upon reading the following detailed description of the preferred embodiments. The drawings are only for purposes of illustrating the preferred embodiments and are not to be construed as limiting the invention. Also, like reference numerals are used to refer to like parts throughout the drawings. In the drawings:

FIG. 1 is a schematic structural view of a device for extracting, adsorbing and separating effective components of Chinese herbs in an embodiment of the present invention;

fig. 2 is a schematic structural diagram of a purification unit in an extraction, adsorption and separation device according to an embodiment of the present invention.

Description of the drawings:

1-a filtration unit; 11-a filtering tank;

12-first-stage filter screen; 13-secondary filter screen;

14-residue port; 15-a filtration membrane module;

2-a separation and concentration unit; 21-a concentration tank;

211-a first liquid inlet; 212-a liquid outlet;

213-vacuum port; 214-an exhaust fan;

215-a liquid outlet control valve; 22-heating jacket;

23-heating plate; 24-a base;

25-stirring magnetons; 3-a purification unit;

31-a chromatography column; 311-a first cylinder;

312-a second cylinder; 32-sealing cover;

321-a second liquid inlet; 322-pressure gauge;

323-relief valve; 33-a liquid inlet pipe;

34-a peristaltic pump; 35-a liquid outlet pipe;

36-a sample collector; 37-liquid inlet control valve.

Detailed Description

The technical solutions of the present invention will be described clearly and completely with reference to the accompanying drawings and detailed description, but those skilled in the art will understand that the following described embodiments are some, not all, of the embodiments of the present invention, and are only used for illustrating the present invention, and should not be construed as limiting the scope of the present invention. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention. The examples, in which specific conditions are not specified, were conducted under conventional conditions or conditions recommended by the manufacturer. The reagents or instruments used are not indicated by the manufacturer, and are all conventional products available commercially.

In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and simplification of description, but do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus, should not be construed as limiting the present invention. Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.

In the description of the present invention, it is to be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "connected," and "connected" are to be construed broadly, and may be, for example, fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present invention can be understood in specific cases to those skilled in the art.

The utility model provides a device for extracting, adsorbing and separating effective components of traditional Chinese medicine, which comprises a raw material tank, wherein the raw material tank is sequentially connected with a filtering unit, a separation and concentration unit and a purification unit;

the filter unit comprises a filter tank, a primary filter screen and a secondary filter screen are vertically arranged in the filter tank, a residue port is arranged at the bottom of the filter tank, and a control valve for controlling residue discharge is arranged on the residue port;

the separation and concentration unit comprises a concentration tank, the outer wall of the concentration tank is sleeved with a heating jacket for introducing heating oil, and a plurality of heating plates are arranged in the heating jacket;

purification unit includes the chromatography cylinder, the chromatography cylinder is including first cylinder and the second cylinder that from top to bottom sets up, first cylinder with can dismantle the connection between the second cylinder, the chromatography cylinder intussuseption is filled with macroporous resin.

Above-mentioned extraction, absorption, separator, through adopting the mode that continuous unit carries out concentrated traditional chinese medicine active ingredient, fully improved the purification effect.

For the utility model discloses a filter unit, the one-level filter screen and the second grade filter screen of setting can guarantee to carry out prefilter to the residue in the raw materials liquid, and the residue after the filtration is detained in the bottom of filtering ponds, when the residue piles up more, the opening of accessible control valve control filtering ponds bottom residue mouth is closed to realize that the residue is discharged smoothly from the residue mouth.

The residue outlet is convenient for slag discharge, and a plurality of residue outlets can be arranged at the bottom.

Furthermore, the filtering unit comprises a filtering membrane component, the filtering membrane component is connected with the filtering tank, and the filtering membrane component can filter the raw material liquid medicine more finely, so that active ingredients with high content of small molecular substances are more reserved in the liquid medicine.

To the utility model discloses a separation concentration unit, the liquid medicine carries out evaporative concentration through the boiling point difference of every composition, is provided with a plurality of hot plates in the heating jacket outside concentrated jar in order to improve concentrated effect, preferably respectively sets up a hot plate in the heating jacket of each side.

Further, the top of concentrated jar is provided with first inlet, first inlet is 45 degrees with the contained angle of horizontal direction, the bottom of concentrated jar is provided with the liquid outlet, and 45 degrees feeding can reduce feed rate for the feeding is gentler, avoids the feeding too fast, splashes in inner space easily, reduces the operational safety nature.

Further, the top of concentrated jar is provided with the evacuation mouth, the evacuation mouth is connected with the air exhauster, can realize taking away the separation that the gaseous phase of evaporation is quick.

Further, the bottom of the concentration tank is close to the position of the liquid outlet and is provided with a base with a magnetic field, a stirring magneton is placed on the base, the stirring mode of the stirring magneton can ensure that the stirring is more sufficient and uniform, and the concentration and purification effect of the liquid medicine is improved.

Furthermore, a liquid outlet control valve is arranged on the liquid outlet, and the liquid output from the liquid outlet is effectively controlled.

To the utility model discloses a purification unit provides a split type macroporous resin chromatographic column, and upper and lower two-layer cylinder can be dismantled mutually, has made things convenient for follow-up dismantlement operation like this, and is also more convenient during the use, can realize zonulae occludens after the butt joint.

Further, first cylinder bottom is provided with the lug, second cylinder top is provided with the recess, the lug with the recess mutually supports in order to realize dismantling the connection. In addition, other detachable connection modes are also within the protection scope of the present invention.

Furthermore, a buckle matched with each other is arranged between the first cylinder and the second cylinder. In order to guarantee that the first cylinder and the second cylinder are fixed after being butted with each other, the buckle matched with each other is arranged between the first cylinder and the second cylinder, the specific structure of the buckle can be formed by uniformly distributing a plurality of clamping blocks in the circumferential direction of the first cylinder and the second cylinder, and the clamping connection can be carried out more tightly after the butt joint.

Furthermore, the mutually matched parts of the convex block and the groove are provided with buffer pads. The buffer pad has excellent static buffer performance and can also play a certain sealing effect.

Further, the top of first cylinder is provided with the closing cap, be provided with the second inlet on the closing cap, the second inlet is connected with the feed liquor pipe, the feed liquor union coupling has the peristaltic pump for realize that the feed liquid is in be interrupted the feeding on the chromatography cylinder, the bottom of second cylinder is connected with the drain pipe. In order to promote the purification effect of sample, the feed liquor pipe still is connected with the peristaltic pump, and the peristaltic pump has realized the mode of intermittent feeding, has promoted the dwell time of sample in the post for it is more abundant to adsorb the purification, and the purification effect is more excellent.

Furthermore, the chromatography cylinder is a plurality of, every connect in parallel each other between the chromatography cylinder, every the feed liquor pipe at chromatography cylinder top converges the back with the peristaltic pump links to each other, every the drain pipe of chromatography cylinder bottom converges the back and is connected with the sample collector. In order to improve the purification effect, a plurality of macroporous resin chromatographic columns can be connected in parallel for operation, and the purification operation is carried out simultaneously.

Furthermore, each liquid inlet pipe is provided with a liquid inlet control valve used for selecting a liquid flowing through the pipeline. The liquid inlet control valve is designed to be capable of selectively controlling each flow pipeline, and the liquid flow pipeline is controlled by opening and closing the liquid inlet control valve.

Further, a pressure gauge and a pressure relief valve are arranged on the sealing cover. So as to prevent the over-high pressure in the chromatographic column and the potential safety hazard.

Further, the feed liquor pipe with the material of drain pipe is soft materials, further can be plastics material or rubber material etc. for example the PVC material can.

In order to clarify the technical solution of the present invention, the following description is made in the form of specific embodiments.

Examples

As shown in fig. 1-2, the embodiment of the present invention provides a device for extracting, adsorbing and separating effective components of traditional Chinese medicine, which comprises a raw material tank and three operation units, wherein the raw material tank is sequentially connected with a filtering unit 1, a separation and concentration unit 2 and a purification unit 3.

The filtering unit 1 comprises a filtering tank 11, a primary filtering net 12 and a secondary filtering net 13 are vertically arranged in the filtering tank 11, a residue port 14 is arranged at the bottom of the filtering tank 11, the residue port 14 can be arranged in a plurality of modes, and is uniformly arranged at the bottom in the filtering tank 11 side by side, and a control valve for controlling the slag discharge is further arranged on the residue port 14. In addition, the filtering unit 1 further comprises a filtering membrane assembly 15, the filtering membrane assembly 15 is connected with the filtering tank 11, and the filtering membrane assembly 15 can filter the raw material liquid medicine more finely and retain more effective components with high content of small molecular substances. The primary filtration of the raw material liquid medicine can be realized through the filter unit 1.

The separation and concentration unit 2 comprises a concentration tank 21, a heating jacket 22 for introducing heating oil is sleeved on the outer wall of the concentration tank 21, a plurality of heating plates 23 are arranged in the heating jacket 22, and the heating plates 23 are arranged to improve the heating and concentration effect. Be provided with first inlet 211 at the top of concentrated jar 21, for control feed rate, first inlet 211 is 45 degrees with the contained angle of horizontal direction, the bottom of concentrated jar 21 is provided with liquid outlet 212, is provided with out liquid control valve 215 on the liquid outlet 212, carries out effectual control to going out liquid. Concentrated jar 21's top is provided with evacuation mouth 213, evacuation mouth 213 is connected with air exhauster 214, and air exhauster 214 can take away the real-time entrainment of the gaseous phase of evaporation, and concentrated jar 21's bottom is close to the position of liquid outlet 212 is provided with the base 24 of taking the magnetic field, lay stirring magnet 25 on the base 24, intensive stirring to the liquid medicine volume of going out from liquid outlet 212 is controlled.

Purification unit 3 includes chromatography column 31, chromatography column 31 is including first cylinder 311 and the second cylinder 312 that from top to bottom sets up, first cylinder 311 with can dismantle the connection between the second cylinder 312, chromatography column 31 intussuseption is filled with macroporous resin. The top of first cylinder 311 is provided with closing cap 32, is provided with second inlet 321, manometer 322 and relief valve 323 on the closing cap 32 respectively, and second inlet 321 is connected with feed liquor pipe 33, and feed liquor pipe 33 is connected with peristaltic pump 34 in order to realize the intermittent feeding of sample, and the bottom of second cylinder 312 is connected with drain pipe 35, and drain pipe 35 is connected with sample collector 36, and sample collector 36 is used for collecting the sample liquid that contains the active ingredient.

The liquid outlet pipe 35 of this embodiment is further provided with a flow controller for controlling the flow rate, and in order to monitor the flow more conveniently, the flow controller is provided with a display screen for displaying the flow.

What first cylinder 311 and second cylinder 312 taken in this embodiment is the mode of can dismantling the connection, is provided with the lug specifically in the bottom of first cylinder 311, and second cylinder 312 top is provided with the recess, first cylinder 311 with be provided with the buckle of mutually supporting between the second cylinder 312, and the lug docks the back with the recess each other, passes through buckle sealing joint with first cylinder 311 and second cylinder 312 through the rotation to guarantee good fixed effect, the leakproofness is more excellent moreover. In order to improve the sealing performance between the first cylinder 311 and the second cylinder 312 and buffer the stress, a buffer pad is further disposed at the matching portion of the protrusion and the groove.

In the purification unit 3 of this embodiment, there are a plurality of chromatography columns 31, each chromatography column 31 is connected in parallel, the liquid inlet pipe 33 at the top of each chromatography column 31 is connected to the peristaltic pump 34 after being converged, and the liquid outlet pipe 35 at the bottom of each chromatography column 31 is connected to the sample collector 36 after being converged. In order to facilitate the selection of the flow-through line, a liquid inlet control valve 37 is provided on each liquid inlet pipe 33. The liquid inlet control valve 37 may be a ball valve, a butterfly valve, or a solenoid valve.

The material of liquid inlet pipe 33 and liquid outlet pipe 35 is preferably soft material, which is flexible when operated manually. Of course, hard materials may be used to facilitate the installation of other components.

Finally, it should be noted that: the above embodiments are only used to illustrate the technical solution of the present invention, and not to limit the same; although the present invention has been described in detail with reference to the foregoing embodiments, it should be understood by those skilled in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some or all of the technical features may be equivalently replaced; such modifications and substitutions do not depart from the spirit and scope of the present invention.

Claims (10)

1. The device for extracting, adsorbing and separating the effective ingredients of the traditional Chinese medicine is characterized by comprising a raw material tank, wherein the raw material tank is sequentially connected with a filtering unit, a separation and concentration unit and a purification unit;

the filter unit comprises a filter tank, a primary filter screen and a secondary filter screen are vertically arranged in the filter tank, a residue port is arranged at the bottom of the filter tank, and a control valve for controlling residue discharge is arranged on the residue port;

the separation and concentration unit comprises a concentration tank, the outer wall of the concentration tank is sleeved with a heating jacket for introducing heating oil, and a plurality of heating plates are arranged in the heating jacket;

purification unit includes the chromatography cylinder, the chromatography cylinder is including first cylinder and the second cylinder that from top to bottom sets up, first cylinder with can dismantle the connection between the second cylinder, the chromatography cylinder intussuseption is filled with macroporous resin.

2. The extraction, adsorption and separation device of claim 1, wherein a first liquid inlet is arranged at the top of the concentration tank, an included angle between the first liquid inlet and the horizontal direction is 45 degrees, and a liquid outlet is arranged at the bottom of the concentration tank.

3. The extraction, adsorption and separation device of claim 1, wherein a vacuum-pumping port is arranged at the top of the concentration tank, and the vacuum-pumping port is connected with an exhaust fan.

4. The extraction, adsorption and separation apparatus as claimed in claim 2, wherein a base with a magnetic field is disposed at the bottom of the concentration tank near the liquid outlet, and the base is provided with a stirring magnet.

5. The extraction, adsorption and separation device according to claim 1, wherein the filtration unit comprises a filtration membrane module, and the filtration membrane module is connected with the filtration tank.

6. The extraction, adsorption and separation apparatus as claimed in claim 2, wherein said liquid outlet is provided with a liquid outlet control valve.

7. The extraction, adsorption and separation device of claim 2, wherein a sealing cover is arranged on the top of the first column body, a second liquid inlet is arranged on the sealing cover, the second liquid inlet is connected with a liquid inlet pipe, the liquid inlet pipe is connected with a peristaltic pump for realizing discontinuous feeding of the liquid on the chromatography column body, and a liquid outlet pipe is connected on the bottom of the second column body.

8. The extraction, adsorption and separation device of claim 7, wherein the number of the chromatography columns is multiple, each chromatography column is connected in parallel, a liquid inlet pipe at the top of each chromatography column is connected with the peristaltic pump after being converged, and a liquid outlet pipe at the bottom of each chromatography column is connected with a sample collector after being converged.

9. The apparatus for extraction, adsorption and separation according to claim 8, wherein each of said liquid inlet pipes is provided with a liquid inlet control valve for selectively flowing through the pipeline.

10. The extraction, adsorption and separation device of claim 7, wherein the sealing cover is provided with a pressure gauge and a pressure relief valve.

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