CN213209991U - Electrospray extraction ionization mass spectrometry detection system for new coronary pneumonia - Google Patents
Electrospray extraction ionization mass spectrometry detection system for new coronary pneumonia Download PDFInfo
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Abstract
The utility model provides a new crown pneumonia electrospray extraction ionization mass spectrometry detecting system relates to medical science detection technology field to solve the technical problem that exists among the prior art adopts nucleic acid detection operation complicacy, detection time is long, the detection cost is higher to new crown pneumonia detection, the device including separate the storehouse, with the detection device who separates the storehouse and be connected, wherein: the isolation bin comprises a bin body, one side of the bin body is provided with a bin door, and a gas transmission channel is arranged in the bin body; the detection device comprises a closed type sterilizing gas detection ion source and a mass spectrometer connected with the closed type sterilizing gas detection ion source; one end of the gas transmission channel is positioned in the bin body and is connected with the gas input end, the other end of the gas transmission channel is positioned outside the bin body, and the closed type sterilizing gas detection ion source is introduced; mass spectrograph connection terminal treatment facility, the utility model discloses detect quick, easy operation and safe and reliable.
Description
Technical Field
The utility model belongs to the technical field of the medical science detects technique and specifically relates to a new crown pneumonia detecting system is related to.
Background
At present, the new coronary pneumonia is detected by adopting nucleic acid detection, wherein the nucleic acid detection firstly takes a saliva or throat swab sample of a patient, genetic materials in the saliva or throat swab sample are extracted, if viruses exist, the viral genetic material RNA exists in the sample, and the RNA in an extracting solution is reversely transcribed into cDNA. PCR amplification is carried out using primers specific for viral cDNA, and if a viral DNA band is amplified, this indicates the presence of coronavirus in the patient. If the DNA band is not amplified, the patient is judged to have no coronavirus.
The applicant has found that the prior art has at least the following technical problems:
1. the operation is complex;
2. the detection time is long;
3. the detection cost is high.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to provide a new crown pneumonia detecting system to solve that exists among the prior art and detect the technical problem that adopts nucleic acid detection operation complicacy, check-out time are long, the detection cost is higher to new crown pneumonia. The utility model provides a plurality of technical effects that preferred technical scheme among a great deal of technical scheme can produce see the explanation below in detail.
In order to achieve the above purpose, the utility model provides a following technical scheme:
the utility model provides a new crown pneumonia detecting system, including separate the storehouse, with the detection device that separate the storehouse and connect, wherein:
the isolation bin comprises a bin body, a bin door is arranged on one side of the bin body, and a gas transmission channel is arranged in the bin body;
the detection device comprises a closed type sterilizing gas detection ion source and a mass spectrometer connected with the closed type sterilizing gas detection ion source;
one end of the gas transmission channel is positioned in the bin body and is connected with a gas input end, the other end of the gas transmission channel is positioned outside the bin body, and the closed type sterilizing gas detection ion source is introduced;
the mass spectrometer is connected with terminal processing equipment.
The utility model provides a new crown pneumonia detecting system can keep apart the patient and prevent cross infection and quick noninvasive sampling, but based on mass spectrograph short-term test exhalation gas, only need use a small amount of reagent with regard to detectable pneumonia, has that detection speed is fast, 30s can go out the result, easy operation, safe and reliable's advantage moreover.
Optionally, the closed type sterilizing gas detection ion source comprises a closed type shell, a spray head is arranged inside the shell, a circuit board is fixed inside the shell, the circuit board is arranged opposite to the spray head, a plurality of ultraviolet lamp beads are arranged on the circuit board, the spray head is fixed inside the shell through a spray head support, the spray head is connected with a connecting pipe, a heating pipe is sleeved outside the connecting pipe, and a sample in the spray head is heated through the heating pipe; the three-dimensional adjusting mechanism comprises an X-axis motor used for adjusting the position of the X axis of the spray head, a Y-axis motor used for adjusting the position of the Y axis of the spray head, a Z-axis motor used for adjusting the position of the Z axis of the spray head and a rotating shaft motor used for adjusting the angle of the spray head, and the X-axis motor, the Y-axis motor, the Z-axis motor and the rotating shaft motor are respectively connected with the spray head support.
Preferably, the storehouse body includes buffer zone and negative pressure zone, the one end of gaseous transmission passageway set up in the negative pressure zone, the buffer zone with be equipped with the negative pressure zone door between the negative pressure zone, wherein:
and the buffer area and the negative pressure area are both internally provided with a disinfection device and a fresh air system.
Adopt negative pressure district door to distinguish buffer zone and negative pressure and set up, the patient that awaits measuring gets into the negative pressure district after the buffer zone buffering and detects, and single isolation avoids cross infection, more can ensure the security of the patient that awaits measuring and the accuracy and the stability of testing result.
Preferably, the disinfection device comprises an ultraviolet lamp tube and an atomizing nozzle which are respectively arranged at the top of the buffer zone and the top of the negative pressure zone, and the atomizing nozzle is communicated with the disinfection solution through a pipeline. And ultraviolet irradiation and spraying are adopted for double disinfection, so that the safety of the internal environment of the buffer zone and the negative pressure zone is ensured.
Preferably, the new trend system includes new trend air supply system and new trend exhaust system, wherein:
fresh air supply system includes: the fresh air filtering box and the fresh air blower are sequentially connected through an air inlet pipeline;
fresh air exhaust system includes: the air exhaust device comprises an exhaust fan and an exhaust pipeline connected with the exhaust fan. Continuously send into fresh air to the internal of storehouse through setting up new trend system to at the internal pressure-fired environment that forms in storehouse, and extrude the storehouse body with the dirty air in the storehouse originally.
Preferably, the fresh air systems are arranged into two sets, the end parts of the two air inlet pipelines respectively extend into the buffer area and the negative pressure area from the top of the bin body, and the two air exhaust pipelines respectively extend out of the buffer area and the negative pressure area from the lower part of the bin body, so that the ventilation effect is good.
Preferably, the tail gas sterilization device is further included, and an air outlet of the exhaust pipeline is communicated into the tail gas sterilization device to further sterilize the tail gas, so that the gas discharged into the air is safe gas without viruses.
Preferably, the buffer area and the negative pressure area are both provided with an air suction opening, the two air suction pipelines respectively extend out of the buffer area and the negative pressure area through the air suction opening and are matched with the air suction opening through the arrangement of the air suction pipelines, and the air suction pipelines are matched with the tail gas sterilizing device to sterilize tail gas after extending out of the buffer area and the negative pressure area.
Preferably, the device further comprises a control system, wherein the control system comprises a control box and a man-machine intersection screen connected with the control box, the man-machine intersection screen is arranged on the side wall of the bin body, and the control box is arranged at the top end of the bin body;
the bin gate, the sterilizing device, the fresh air system and the tail gas sterilizing system are controlled by the control box, the man-machine intersection screen sends instructions of corresponding functions to the control box, and the control box controls corresponding parts to complete the use of the isolation bin.
Preferably, the disinfection solution is chlorine dioxide, the chlorine dioxide is used for efficiently, powerfully and quickly killing the new coroneumoniae virus, and other viruses and fungi are also disinfected, so that the environment in the bin body is ensured to meet the use requirement.
Preferably, the isolation bin further comprises universal wheels arranged at the bottom of the bin body, the isolation bin can be moved to a required position according to use requirements by arranging the universal wheels, and the isolation bin is convenient to use and move.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to these drawings without creative efforts.
Fig. 1 is a schematic structural diagram of an embodiment of an electrospray extraction ionization mass spectrometry detection system for new coronary pneumonia provided by the present invention;
fig. 2 is a schematic front view of an embodiment of the electrospray extraction ionization mass spectrometry detection system for new coronary pneumonia provided by the present invention;
FIG. 3 is a schematic diagram of an internal structure of an embodiment of the electrospray extraction ionization mass spectrometry detection system for new coronary pneumonia provided by the present invention;
fig. 4 is a schematic rear view of an embodiment of the electrospray extraction ionization mass spectrometry detection system for new coronary pneumonia provided by the present invention;
FIG. 5 is a schematic diagram of the operation of an embodiment of the electrospray extraction ionization mass spectrometry detection system for new coronary pneumonia provided by the present invention;
figure 6 is for utilizing the utility model provides a new crown pneumonia electrospray extraction ionization mass spectrometry detecting system is respectively to three types of people: the fingerprint spectrogram of the exhaled gas is obtained by analyzing normal persons, negative patients and positive patients;
fig. 7 is an AI algorithm analysis flowchart of the present invention.
In the figure: 1. a bin body; 2. a bin gate; 3. a closed type sterilizing gas detection ion source; 4. a mass spectrometer; 5. A terminal processing device; 7. a fresh air supply system; 8. a fresh air exhaust system; 9. a control box; 10. a man-machine intersection screen; 11. a buffer area; 12. a negative pressure region; 13. an air suction opening; 20. a universal wheel; 61. an ultraviolet lamp tube; 62. an atomizing spray head; 71. a fresh air filtering tank; 72. a fresh air blower; 73. an air inlet pipeline; 81. an exhaust fan; 82. a tail gas sterilizing device; 83. an air draft pipeline.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention clearer, the technical solutions of the present invention will be described in detail below. It is to be understood that the embodiments described are only some embodiments of the invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by a person skilled in the art without creative efforts belong to the protection scope of the present invention.
The utility model provides a new crown pneumonia electrospray extraction ionization mass spectrometry detecting system, figure 1 are the schematic structure of this embodiment, as shown in figure 1, including separating the storehouse, with the detection device who separates the storehouse and be connected, in this embodiment, separate the storehouse and adopt portable small-size separation storehouse, the technical index design of its technical parameter reference P3 laboratory, wherein:
the isolation bin comprises a bin body 1, a bin door 2 is arranged on one side of the bin body 1, the bin door 2 is an automatic door and is controlled by a control system, and a gas transmission channel is arranged in the bin body 1;
the detection device comprises a closed type sterilizing gas detection ion source 3 and a mass spectrometer 4 connected with the closed type sterilizing gas detection ion source 3; one end of the gas transmission channel is positioned in the bin body 1 and is connected with a gas input end, in the embodiment, the gas input end adopts a disposable blowing nozzle to prevent cross infection, the other end of the gas transmission channel is positioned outside the bin body 1 and is introduced into the closed type sterilizing gas detection ion source 3, in the embodiment, the gas transmission channel is formed by connecting a gas pipe on the bin wall of a negative pressure area 12 of the isolation bin, and the gas pipe is introduced into the closed type sterilizing gas detection ion source 3 from the negative pressure area 12; the mass spectrometer 4 is connected to a terminal processing device 5, and in this embodiment, the terminal processing device is a computer.
Optionally, the closed type sterilizing gas detection ion source comprises a closed type shell, a spray head is arranged inside the shell, a circuit board is fixed inside the shell, the circuit board is arranged opposite to the spray head, a plurality of ultraviolet lamp beads are arranged on the circuit board, the spray head is fixed inside the shell through a spray head support, the spray head is connected with a connecting pipe, a heating pipe is sleeved outside the connecting pipe, and a sample in the spray head is heated through the heating pipe;
optionally, a three-dimensional adjusting mechanism is arranged in the housing, the three-dimensional adjusting mechanism includes an X-axis motor for adjusting the position of the X-axis of the nozzle, a Y-axis motor for adjusting the position of the Y-axis of the nozzle, a Z-axis motor for adjusting the position of the Z-axis of the nozzle, and a rotating-axis motor for adjusting the angle of the nozzle, and the X-axis motor, the Y-axis motor, the Z-axis motor, and the rotating-axis motor are respectively connected to the nozzle support.
When the device is used, the movable small isolation bin is firstly opened and disinfected, then the mass spectrometer 4 is opened, the closed type sterilizing gas detection ion source 3 is well adjusted, a patient to be detected enters the isolation bin and blows air into the closed type sterilizing gas detection ion source 3 through a gas transmission channel on the isolation bin, the mass spectrometer 4 is simultaneously connected with carrier gas such as nitrogen and an extractant reagent through another sample inlet, the selected extractant reagent can be a mixture of methanol and water, the volume ratio is preferably 1:1, the patient to be detected finishes blowing air and leaves the isolation bin to disinfect the isolation bin, a spectrogram is obtained through the mass spectrometer 4, and a detector processes spectrogram data through a computer and analyzes whether the exhaled air has characteristics of metabolites such as pneumonia or not, so that the existence of pneumonia can be known. The system can isolate patients and perform rapid noninvasive sampling, can rapidly detect expired gas based on a mass spectrometer, can detect pneumonia only by using a small amount of reagents, and has the advantages of high detection speed, simplicity in operation and low cost.
As an optional implementation manner, fig. 2 is a schematic front view structure diagram of the present embodiment, as shown in fig. 2, the bin body 1 includes a buffer area 11 and a negative pressure area 12, one end of the gas transmission channel is disposed in the negative pressure area 12, a negative pressure area door is disposed between the buffer area 11 and the negative pressure area 12, the negative pressure area door also adopts an automatic door, and is controlled by a control system, wherein:
all be equipped with degassing unit and new trend system in buffer 11 and the negative pressure zone 12, adopt the negative pressure zone door to separately set up buffer 11 and negative pressure zone 12, the patient that awaits measuring gets into negative pressure zone 12 after buffer 11 cushions and detects, and single isolation avoids cross infection, more can ensure the security of the patient that awaits measuring and the accuracy and the stability of testing result.
As an alternative embodiment, fig. 3 is a schematic diagram of the internal structure of this embodiment, and as shown in fig. 3, the disinfecting device includes an ultraviolet lamp 61 and an atomizing nozzle 62 respectively disposed at the top of the buffer zone 11 and the top of the negative pressure zone 12, in this embodiment, the ultraviolet lamp 61 and the atomizing nozzle 62 are controlled by the control system to perform automatic disinfection, the atomizing nozzle 62 is communicated with the disinfecting liquid through a pipeline, after the patient leaves the buffer zone 11, the disinfecting liquid is irradiated through the ultraviolet lamp 61 of the buffer zone 11, and the atomization nozzle 62 is adopted to spray disinfection medicine to carry out powerful disinfection and sterilization on the virus, after the isolated patient leaves the negative pressure zone 12, the ultraviolet lamp 61 of the negative pressure zone 12 irradiates, and the atomizing nozzle 62 is adopted to spray disinfection medicine to carry out powerful disinfection and killing on the virus, and ultraviolet irradiation and spraying double disinfection and killing are adopted to ensure the safety of the internal environment of the buffer zone 11 and the negative pressure zone 12.
Preferably, the disinfection solution is chlorine dioxide, which has strong killing capacity on bacteria, viruses and fungal spores, and is used for efficiently, powerfully and quickly killing the new coroneumoniae virus and disinfecting other viruses and fungi, so that the environment in the bin body 1 can meet the use requirements.
As optional implementation mode, fig. 4 is a schematic diagram of the rear view structure of this embodiment, as shown in fig. 4, the fresh air system includes fresh air supply system 7 and fresh air exhaust system 8, continuously sends fresh air into the cabin body through setting up the fresh air system, and forms the micro-positive pressure environment in the cabin body, and extrudes the originally dirty air in the cabin body out of the cabin body, wherein:
the fresh air supply system 7 comprises a fresh air filter box 71 and a fresh air supply blower 72, and an air supply pipeline 73 is sequentially connected with the fresh air filter box 71 and the fresh air supply blower 72;
fresh air exhaust system 8 includes: an air blower 81 and an air suction line 83 connected to the air blower 81.
Specifically, the fresh air systems are provided with two sets, the end parts of the two air inlet pipelines 73 respectively extend into the buffer area 11 and the negative pressure area 12 from the top part of the bin body 1, and the two air exhaust pipelines 83 respectively extend out of the buffer area 11 and the negative pressure area 12 from the lower part of the bin body 1.
As an optional embodiment, the exhaust gas disinfection device 82 is further included, and an air outlet of the exhaust pipeline 83 is communicated into the exhaust gas disinfection device 82 to further disinfect the exhaust gas, so that the gas discharged into the air is ensured to be safe gas without viruses.
As an alternative embodiment, the buffer area 11 and the negative pressure area 12 are both provided with the suction opening 13, and the two suction pipes 83 respectively extend out of the buffer area 11 and the negative pressure area 12 through the suction opening 13.
As an optional embodiment, the isolation bin further comprises a universal wheel 20 arranged at the bottom of the bin body 1, and the isolation bin can be moved to a required position according to use requirements through the universal wheel 20, so that the isolation bin is convenient to use and move.
As an optional implementation mode, the isolation cabin further comprises a control system, the control system comprises a control box 9 and a man-machine intersection screen 10 connected with the control box 9, the man-machine intersection screen 10 is arranged on the side wall of the cabin body 1, the control box 9 is arranged at the top end of the cabin body 1, a worker clicks the function on the man-machine intersection screen 10, the man-machine intersection screen 10 sends the instruction of the corresponding function to the control box 9, and the control box 9 controls the corresponding component to complete the use of the isolation cabin.
Fig. 5 is a working schematic diagram of the embodiment, and as shown in fig. 5, the bin door 2, the negative pressure region door, the sterilizing device, the fresh air supply system 7, the fresh air exhaust system 8 and the tail gas sterilizing device 82 are all controlled by the control box 9.
The utility model discloses a working process does:
1. the movable small isolation bin is moved to a proper position, the isolation bin is electrified, the air exhaust system starts to work, the automatic door is closed, the isolation bin maintains the pressure of the buffer zone lower than the external 40Pa, the negative pressure zone 12 maintains the pressure of the buffer zone lower than the external 60Pa, and the tail gas sterilizing device 82 starts to work.
2. Opening the man-machine intersection screen 10, and double-clicking the isolation bin opening control software to enter a man-machine intersection interface;
3. and clicking 'disinfection' in a man-machine intersection interface, opening an ultraviolet lamp in the isolation bin, and starting spraying and disinfecting for 30 seconds.
4. After killing is finished, clicking 'enter buffer zone' in the man-machine intersection interface, automatically opening the door 2, enabling a patient needing isolation to enter the buffer zone 11, and automatically closing the door after waiting for 6 seconds after opening the door 2.
5. After the negative pressure of the buffer area 11 is stabilized, clicking 'enter the negative pressure area' in the man-machine intersection interface, automatically opening the negative pressure area door, enabling a patient needing to be isolated to enter the negative pressure area 12 for isolation, and waiting for 6 seconds to automatically close the door after opening the negative pressure area door.
6. 5 seconds after the patient needing isolation enters the negative pressure zone 12, the buffer zone 11 automatically turns on the ultraviolet lamp and sprays to sterilize, and the safety of the buffer zone 11 is ensured.
7. After entering the negative pressure region 12, the isolated patient blows air against a disposable mouthpiece in the chamber body, and the air exhaled by the patient enters the closed type killing ion source through an air transmission channel on the isolation chamber;
8. obtaining a spectrogram through a mass spectrometer 4;
9. and (4) blowing the patient to be detected, leaving the isolation bin, disinfecting the isolation bin, and processing spectrogram data by the detector to obtain a result.
The utility model provides a detection application example of new crown pneumonia electrospray extraction ionization mass spectrometry detecting system (EESI-MS) is introduced below.
1) Detection process
During detection, a test object enters the negative pressure region 12 (with a mask) to wait, enters the buffer region 11 (with a low negative pressure, delta P is-40 Pa, the mask is worn) after the buffer region 11 is sterilized, and enters the negative pressure region 12 (with a low negative pressure, delta P is-60 Pa) after pressure is balanced. After the pressure in the negative pressure region 12 is balanced, the breathing is adjusted, the mask is taken off, the exhalation detection is carried out by using the disposable mouthpiece, the gas exhaled by the detection object enters the closed type killing ion source through the gas transmission channel on the isolation bin, and then enters the mass spectrum to begin to collect the fingerprint spectrogram of the exhaled gas. After the blowing is finished, the disposable blowing nozzle is taken down and placed at a blowing nozzle collecting position which is specially used for collecting, and the user wears the mask and leaves. After the bin gate is closed, the whole negative pressure bin body is sprayed and disinfected by ultraviolet lamps and chlorine dioxide in a spraying mode comprehensively, and the next test is carried out after disinfection is finished.
2) Sample analysis
Analyzing the exhaled gas obtained in the step 1), wherein the exhaled gas consists of a plurality of complex molecules, and the difference between the types and the content of the molecules forms the molecular fingerprint of the exhaled gas sample. Adopt the utility model provides a new coronary pneumonia electrospray extraction ionization mass spectrum detecting system is positive patient, negative patient's exhalation gaseous sample direct analysis to normal person and nucleic acid detection, has obtained the one-level mass spectrum fingerprint spectrogram of different samples, as shown in figure 6. As can be seen by comparing the primary fingerprints of the three groups of samples, the main mass spectrum peaks are similar among normal persons, positive patients and negative patients, including m/z 59 (acetone), m/z 193(citric acid ), m/z 61 (urea), m/z 114(creatinine ), m/z 74(N, N-dimethylformamide, N, N-dimethylformamide), m/z 60(trimethylamine ), m/z 74 (N-isopyropylmethylamine, N-isopropylamine), m/z 79(dimethyl sulfoxide ), m/z 88(N, N-dimethylacetamide, N, N-dimethylacetamide) and the like.
3) Determination of results
As shown in fig. 7, the detection result data are compared and distinguished by 5 different artificial intelligence means and algorithms respectively; the five algorithms are respectively: the support vector machine, the random forest, the naive Bayes, the multilayer neural network and the TensorFlow are all the existing mature algorithms with high reliability, if the results respectively judged by 4 or 5 methods indicate that the molecular fingerprint of the exhaled gas sample of the detected person conforms to the fingerprint characteristics of the exhaled gas of the new coronavirus infected person, the patient is judged to be a new coronavirus pneumonia patient, namely positive; if 3 or more than 3 judgment results are not considered to be in accordance with the characteristics of the patient with the new coronavirus pneumonia, judging that the patient is a person infected by the non-new coronavirus, namely, judging that the patient is negative; otherwise, the patient is suspected to have the new coronavirus pneumonia.
Use the utility model provides a new coronary pneumonia electrospray extraction ionization mass spectrometry detection system has carried out pharynx swab nucleic acid detection and this method detection to the 205 detection objects of the first affiliated hospital of Nanchang university, and the result contrasts, and the coincidence rate reaches 95.2%, and the degree of accuracy is very high.
The detection system has the advantages that the isolation bin is movable, negative pressure isolation is adopted, ultraviolet irradiation and spraying are carried out in a double-sterilization mode, a single person is isolated, cross infection is avoided, the mobile small isolation bin is small in occupied area, rapid detection can be carried out at any time, the cleaning is convenient, no pollution is caused, the detection result only needs 30s, and the detection efficiency is greatly improved compared with the nucleic acid detection which outputs the result in several hours.
The above description is only for the specific embodiments of the present invention, but the protection scope of the present invention is not limited thereto, and any person skilled in the art can easily think of the changes or substitutions within the technical scope of the present invention, and all should be covered within the protection scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the claims.
Claims (10)
1. The electrospray extraction ionization mass spectrum detection system for the new coronary pneumonia is characterized in that: the device comprises an isolation bin and a detection device connected with the isolation bin, wherein:
the isolation bin comprises a bin body, a bin door is arranged on one side of the bin body, and a gas transmission channel is arranged in the bin body;
the detection device comprises a closed type sterilizing gas detection ion source and a mass spectrometer connected with the closed type sterilizing gas detection ion source;
one end of the gas transmission channel is positioned in the bin body and is connected with a gas input end, the other end of the gas transmission channel is positioned outside the bin body, and the closed type sterilizing gas detection ion source is introduced;
the mass spectrometer is connected with terminal processing equipment.
2. The electrospray extraction ionization mass spectrometry detection system for neocoronary pneumonia of claim 1, wherein: the storehouse body includes buffer and negative pressure zone, the one end of gas transmission passageway set up in the negative pressure zone, the buffer with be equipped with the negative pressure zone door between the negative pressure zone, wherein:
and the buffer area and the negative pressure area are both internally provided with a disinfection device and a fresh air system.
3. The electrospray extraction ionization mass spectrometry detection system for neocoronary pneumonia of claim 2, wherein: the disinfection device comprises an ultraviolet lamp tube and an atomizing nozzle which are respectively arranged at the top of the buffer zone and the top of the negative pressure zone, and the atomizing nozzle is communicated with the disinfectant through a pipeline.
4. The electrospray extraction ionization mass spectrometry detection system for neocoronary pneumonia of claim 3, wherein: the new trend system includes new trend air supply system and new trend exhaust system, wherein:
fresh air supply system includes: the fresh air filtering box and the fresh air blower are sequentially connected through an air inlet pipeline;
fresh air exhaust system includes: the air exhaust device comprises an exhaust fan and an exhaust pipeline connected with the exhaust fan.
5. The electrospray extraction ionization mass spectrometry detection system for neocoronary pneumonia of claim 4, wherein: the fresh air system is provided with two sets, the end parts of the two air inlet pipelines respectively extend into the buffer area and the negative pressure area from the top of the bin body, and the two air exhaust pipelines respectively extend out of the buffer area and the negative pressure area from the lower part of the bin body.
6. The electrospray extraction ionization mass spectrometry detection system for new coronary pneumonia according to claim 4 or 5, characterized in that: the tail gas sterilization device is further included, and an air outlet of the air exhaust pipeline is communicated into the tail gas sterilization device.
7. The electrospray extraction ionization mass spectrometry detection system for neocoronary pneumonia of claim 6, wherein: and air suction ports are arranged in the buffer area and the negative pressure area, and the two air suction pipelines respectively extend out of the buffer area and the negative pressure area through the air suction ports.
8. The electrospray extraction ionization mass spectrometry detection system for neocoronary pneumonia of claim 7, wherein: the control system comprises a control box and a man-machine intersection screen connected with the control box, the man-machine intersection screen is arranged on the side wall of the bin body, and the control box is arranged at the top end of the bin body;
the bin gate, the sterilizing device, the fresh air system and the tail gas sterilizing system are all controlled by the control box.
9. The electrospray extraction ionization mass spectrometry detection system for neocoronary pneumonia of claim 3, wherein: the disinfectant adopts chlorine dioxide.
10. The electrospray extraction ionization mass spectrometry detection system for neocoronary pneumonia of claim 1, wherein: the isolation bin further comprises universal wheels arranged at the bottom of the bin body.
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Effective date of registration: 20220616 Address after: Room 301, floor 3, building 1, yard 19, Jiaomen, Fengtai District, Beijing 100068 Patentee after: Beijing AVIC Baofu Technology Co.,Ltd. Address before: 330013 No. 418, Guanglan Avenue, Qingshanhu District, Nanchang City, Jiangxi Province Patentee before: EAST CHINA INSTITUTE OF TECHNOLOGY |