CN214885872U - Quick nucleic acid detection experiment shelter - Google Patents

Quick nucleic acid detection experiment shelter Download PDF

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Publication number
CN214885872U
CN214885872U CN202120247500.0U CN202120247500U CN214885872U CN 214885872 U CN214885872 U CN 214885872U CN 202120247500 U CN202120247500 U CN 202120247500U CN 214885872 U CN214885872 U CN 214885872U
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China
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area
channel
shelter
experiment
nucleic acid
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CN202120247500.0U
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Chinese (zh)
Inventor
何坚荣
许勇
杨立军
李莉
邱建国
李志杰
庞华
马伟新
李海兵
牛会芳
赵妹青
段宇新
任孝江
王成勇
李锦彬
董家忠
孙成权
宁致远
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Beijing Nuclear Industry Hospital
Beijing Tongfang Qinghuan Technology Co ltd
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Beijing Nuclear Industry Hospital
Beijing Tongfang Clean Tech Co ltd
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Priority to CN202120247500.0U priority Critical patent/CN214885872U/en
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Abstract

The embodiment of the application relates to a quick nucleic acid detection experiment shelter, relates to the technical field of epidemic prevention and biological safety, and mainly aims to improve the safety of the quick nucleic acid detection experiment shelter. The experimental shelter includes: a specimen experiment area; the separation wall is provided with an operation channel and an article transfer channel which are communicated with the specimen experiment area and the personnel operation area; the operation part of the operation glove is arranged in a specimen operation area of the specimen experiment area, and the sleeve part of the operation glove is connected to the operation channel; the article transfer window is arranged in the article transfer channel; regional pressure control, according to the experiment standard requirement, establish different pressure to different regions, through directional air current control pollutant flow direction, ensure operation safety and reduce environmental risk. The experiment operation process of sample, medical personnel pass through the division wall with the sample and keep apart, and operation process is comparatively safe.

Description

Quick nucleic acid detection experiment shelter
Technical Field
The embodiment of the application relates to the technical field of epidemic prevention and biological safety, in particular to a quick nucleic acid detection experiment shelter.
Background
Since the outbreak of new coronavirus, in order to effectively control the disordered spreading of the new coronavirus, a means for preventing and controlling the spreading of the virus is still adopted as an epidemic situation control means before a special specific medicine is not developed. Prevention and control of viral transmission requires first finding a new coronavirus infected person and then isolating the infected person.
In the examination of a new coronavirus infected person, a suspected object needs to be sampled, and then a specimen experiment operation is performed. The sample experiment operation process is internal going on in the sample experiment cabin of a negative pressure, and medical personnel wear isolation clothes and detect the sample of collection in the sample experiment cabin is internal, the test process, because medical personnel and the sample of collection are with being in same space, the risk that leads to the fact medical personnel is higher, if quality problems or medical personnel wear protective clothing scheduling problem in violation of rules and regulations appear in medical personnel's protective clothing, all can lead to medical personnel to take place the condition of viral infection.
SUMMERY OF THE UTILITY MODEL
In view of this, the embodiment of the present application provides a rapid nucleic acid detection experiment shelter, and mainly aims to improve the safety of the rapid nucleic acid detection experiment shelter.
In order to achieve the above purpose, the embodiments of the present application mainly provide the following technical solutions:
the embodiment of the present application provides a quick nucleic acid testing experiment shelter, includes:
a specimen experiment area;
the separation wall is provided with an operation channel and an article transfer channel which are communicated with the specimen experiment area and the personnel operation area;
the operation part of the operation glove is arranged in a specimen operation area of the specimen experiment area, and the sleeve part of the operation glove is connected to the operation channel;
and the article transfer window is arranged in the article transfer channel.
The purpose and the technical problem to be solved by the embodiments of the present application can be further achieved by the following technical measures.
Optionally, the aforementioned fast nucleic acid detecting experiment shelter, wherein the first transmitting end of the article transmission window has a first switchable window, the second transmitting end of the transmission window has a second switchable window, and an article placing space is provided between the first switchable window of the transmission window and the second switchable window of the transmission window.
Optionally, in the aforementioned fast nucleic acid detection experiment shelter, a disinfection ultraviolet lamp is disposed in the article transfer window.
Optionally, in the aforementioned fast nucleic acid detection experiment shelter, the specimen experiment area and the human operation area are both negative pressure working areas.
Optionally, in the aforementioned fast nucleic acid detection experiment shelter, a working pressure of the specimen experiment area is lower than a working pressure of the human operation area.
Optionally, in the aforementioned fast nucleic acid detecting experiment shelter, the specimen experiment area is provided with a specimen transmission channel for delivering a specimen outside the communication chamber, and the article transmission window is further provided in the specimen transmission channel.
Optionally, the aforementioned fast nucleic acid detection experiment shelter, wherein the specimen experiment area comprises: sample processing and amplification analysis chamber, high pressure sterilization chamber.
Optionally, the aforementioned fast nucleic acid detection experiment shelter, wherein the operation channel comprises: a first channel communicating the sample processing and amplification analysis chamber with the personnel operating area, a second channel communicating the autoclaving chamber with the personnel operating area;
the operating glove includes: first glove and second glove:
the operating part of the first glove is arranged in the sample processing and amplification analysis area of the sample experiment area, and the sleeve part of the first glove is connected to the first channel;
the operating part of the second glove is arranged in an autoclave area of the specimen experiment area, and the sleeve part of the second glove is connected to the second channel.
Optionally, the aforementioned fast nucleic acid detection experiment shelter, wherein the article transfer channel comprises: a third channel for communicating the sample processing and amplification analysis chamber with the personnel operating area, and a fourth channel for communicating the sample processing and amplification analysis chamber with the autoclave chamber;
the article delivery windows are arranged in the third channel and the fourth channel;
the sample experimental area is also provided with a sample submission channel communicated with the outside;
the article transfer window is also arranged in the specimen submission channel.
Optionally, the aforementioned fast nucleic acid detection experiment shelter further comprises:
the object conveying mechanism is arranged in the sample processing and amplification analysis chamber and is used for conveying the objects conveyed by the object conveying window of the third channel and the samples conveyed by the object conveying window of the sample delivery channel to the area where the operating part of the first glove is located;
the fast nucleic acid detection experiment shelter is 3 meters long, 2.438 meters wide and 2.5 meters high.
By means of the technical scheme, the rapid nucleic acid detection experiment shelter provided by the technical scheme at least has the following advantages:
among the technical scheme that this scheme embodiment provided, to the sample test in-process, can close the article transmission window, the sample is in the sample experimental area, medical personnel is in personnel's operation area, medical personnel can carry out the detection operation to the sample in sample experimental area in personnel's operation area through the operating glove, area pressure control, according to the experimental standard requirement, establish different pressures to different regions, through directional air current control pollutant flow direction, ensure operation safety and reduce the environmental risk, for prior art, the experimental operation process of sample, medical personnel and sample pass through the division wall and keep apart, operation process is comparatively safe.
The foregoing description is only an overview of the embodiments of the present application, and in order to provide a clear understanding of the technical solutions of the embodiments of the present application and to be implemented in accordance with the content of the description, the following detailed description of the preferred embodiments of the present application is provided in conjunction with the accompanying drawings.
Drawings
Various other advantages and benefits will become apparent to those of ordinary skill in the art upon reading the following detailed description of the preferred embodiments. The drawings are only for purposes of illustrating the preferred embodiments and are not to be construed as limiting the application. Also, like reference numerals are used to refer to like parts throughout the drawings. In the drawings:
FIG. 1 is a schematic top view of a rapid nucleic acid detection laboratory shelter according to an embodiment of the present disclosure;
FIG. 2 is a schematic diagram of an axial measurement structure of a rapid nucleic acid detection experiment shelter provided by an embodiment of the present application.
Detailed Description
Exemplary embodiments of the present disclosure will be described in more detail below with reference to the accompanying drawings. While exemplary embodiments of the present disclosure are shown in the drawings, it should be understood that the present disclosure may be embodied in various forms and should not be limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete, and will fully convey the scope of the disclosure to those skilled in the art.
It is to be noted that, unless otherwise specified, technical or scientific terms used herein shall have the ordinary meaning as understood by those skilled in the art to which this application belongs.
Fig. 1 to 2 show an embodiment of a rapid nucleic acid detection experiment shelter provided in the present application, and referring to fig. 1 to 2, an embodiment of the present application provides a rapid nucleic acid detection experiment shelter comprising:
a specimen experiment area 10;
the human operation area 20 is separated from the specimen experiment area 10 through a separation wall, and the separation wall is provided with an operation channel and an article transfer channel which are communicated with the specimen experiment area 10 and the human operation area 20;
a manipulation glove 30, a manipulation portion of which is provided in a specimen manipulation area of the specimen experiment region 10, and a sleeve portion of which is connected to the manipulation channel of which the manipulation glove 30 is provided;
and an article transfer window 40 disposed in the article transfer passage.
Among the technical scheme that this scheme embodiment provided, to the sample test in-process, can close the article transfer window, the sample is in sample experimental area 10, and medical personnel are in personnel's operation area 20, and medical personnel can carry out the detection operation to the sample of sample experimental area 10 in personnel's operation area 20 through operating gloves 30, and for prior art, the experimental operation process of sample, medical personnel and sample pass through the division wall and keep apart, and operation process is comparatively safe.
In practice, in some embodiments, the rapid nucleic acid detection assay shelter is 3 meters long, 2.438 meters wide, and 2.5 meters high.
The article transfer window 40 is a window that can be opened and closed, and a medical staff can perform a preparation operation of a detection reagent in the staff operation area 20, then place the prepared detection reagent in the specimen experiment area 10 through the article transfer window 40, and then close the article transfer window 40. In implementation, for further improving safety in medical staff, the first conveying end of the article transfer window 40 has a first switchable window 41, the second conveying end of the transfer window has a second switchable window 42, and an article placing space is provided between the first switchable window 41 of the transfer window and the second switchable window 42 of the transfer window. Wherein, set up in the first switch window 41 of article transfer window 40 of article transfer passage is in order to be located personnel's operation area 20, set up in article transfer window 40 second switch window 42 of article transfer passage is located sample experiment area 10 for the example, and medical personnel can open first switch window earlier, then place the article that will pass on in the article and place the space, then close first switch window. The medical staff may operate to open the second openable window by operating the operating glove 30, take out the items of the item placing space, and then close the second openable window. Wherein, a disinfection ultraviolet lamp can be arranged in the article transfer window 40 for disinfecting the articles in the article placing space. The above-described operation method may be used when the distance between the article transfer window 40 and the operation glove 30 is short, and if the distance between the operation glove 30 and the article transfer window 40 in the specimen experiment area 10 is long, the robot may be configured in the specimen experiment area 10 to transfer the article between the operation glove 30 and the article transfer window 40, and the robot may be a robot arm or the like. In other embodiments, the first openable window 41 and the second openable window 42 may be electrically controlled windows, and the control ends of the electrically controlled windows are disposed in the personnel operating area 20, so as to facilitate remote control of the medical staff.
In addition, the specimen experiment area 10 is provided with a specimen transfer channel 11 for delivering a specimen outside the communication chamber, and the article transfer window 40 is also provided in the specimen transfer channel 11. The medical staff outside the cabin can feed the specimen to be examined into the specimen experiment area 10 through the article transfer window 40 of the specimen transfer path 11. In the implementation, when adopting two but in the switch window, medical personnel can open the first switch window of article transfer window 40 of sample transfer passage 11 earlier, then will examine the sample and place the article in and place the space, then close first switch window. The medical staff can operate the second openable window of the article transfer window 40 of the specimen transfer path 11 by operating the operating glove 30, take out the article of the article placing space, and then close the second openable window. Alternatively, the transfer of the articles between the operation glove 30 and the article transfer window 40 of the specimen transfer path 11 is realized by a robot system disposed in the specimen experiment region 10.
In the middle of the work, sample experiment area 10 and personnel operation area 20 are negative pressure work area, prevent that the contaminated air in the quick nucleic acid testing experiment shelter from leaking. Specifically, the working pressure of the specimen experiment area 10 is less than the working pressure of the personnel operating area 20, so that the contaminated air in the specimen experiment area 10 can be prevented from flowing into the personnel operating area 20.
In practice, the experimental mode of the specimen has various modes, the traditional nucleic acid detection time usually needs several hours, and certain special scenes and special crowds often need to rapidly provide the detection result within 1 and 2 hours, so the safety cabin is an experimental environment system developed specially for rapid nucleic acid detection. On the basis of safety, the system has extremely high mobility and deployment performance and is convenient for rapid deployment. In the embodiment provided by the scheme, point-of-care testing (POCT) can be adopted, and the POCT technology is a detection mode which is carried out on a sampling site and utilizes a portable analysis instrument and a matched reagent to quickly obtain a detection result. In practice, the sample processing and amplification analysis can be carried out in the same room, and rapid detection can be realized. Therefore, the rapid nucleic acid detection experiment shelter can realize rapid and flexible detection by applying the POCT technology, and rapid virus detection can be realized only by carrying the rapid nucleic acid detection experiment shelter produced in advance to an epidemic situation outbreak place.
Wherein the specimen experiment area 10 includes: a sample processing and amplification analysis chamber 12 and a high pressure sterilization chamber 13. Medical personnel in personnel's operation area 20 through operation gloves 30, handle the sample and carry out the detection operation to the sample in the amplification analysis room 12, later, place the sample after the detection in autoclaving room 13 and carry out autoclaving, finally, the sample clearance after autoclaving is handled.
Specifically, the operation channel includes: a first channel communicating the sample processing and amplification analysis chamber 12 with the human manipulation area 20, a second channel communicating the autoclaving chamber 13 with the human manipulation area 20; the operating glove 30 includes: first glove 31 and second glove 32: the operation part of the first glove 31 is disposed in the specimen processing and amplification analysis region of the specimen experiment region 10, and the sleeve part of the first glove 31 is connected to the first channel; the operation portion of the second sleeve 32 is disposed in the autoclave region of the specimen experiment region 10, and the sleeve portion of the second sleeve 32 is connected to the second channel. In operation, the medical staff in the staff operation area 20 performs specimen treatment and specimen experiment operation in the amplification analysis area through the first glove 31, and the medical staff in the staff operation area 20 performs specimen sterilization treatment operation in the autoclave 13 through the second glove 32.
Specifically, the article transfer passage includes: a third channel 21 communicating the sample processing and amplification analysis chamber 12 with the human manipulation zone 20, and a fourth channel 22 communicating the sample processing and amplification analysis chamber 12 with the autoclaving chamber 13; the article delivery window 40 is disposed in the third channel 21 and the fourth channel 22; the sample experimental area 10 is also provided with a sample submission channel communicated with the outdoor; the article transfer window is also arranged in the specimen submission channel. The sample to be detected is sent into the sample experimental area 10 through the article transfer window of the sample submission channel, the detection reagent is sent into the sample experimental area 10 through the article transfer window of the third channel 21, and the detected sample is sent into the high-pressure sterilization chamber 13 through the article transfer window of the fourth channel 22.
In the case that the operation gloves 30 and the object transfer windows 40 in the sample experiment area 10 are far away from each other, an object transfer mechanism may be disposed in the sample processing and amplification analysis chamber 12, and the object transfer mechanism is used to transfer the objects transferred through the object transfer windows of the third channel 21 and the samples transferred through the object transfer windows of the sample submission channel to the area where the operation portion of the first glove 31 is located, so as to transfer the objects between each operation glove 30 and each object transfer window 40 in the sample experiment area 10.
In addition, personnel's operation area 20 can be divided into two spaces, and a space is personnel's activity space, and another space is reagent platform for put reagent, can communicate through the window between two spaces, make things convenient for medical personnel to operate the reagent on the reagent platform.
An access door for medical personnel to enter and exit is arranged in the personnel operating area, and a cleaning door for cleaning and transporting the specimen after high-temperature sterilization is arranged in the high-pressure sterilization chamber.
In order to effectively utilize space, electrical equipment such as equipment for providing negative pressure disinfection for the rapid nucleic acid detection experiment shelter can be arranged in an equipment cabin at the bottom of the high-pressure sterilization room.
In the foregoing embodiments, the descriptions of the respective embodiments have respective emphasis, and for parts that are not described in detail in a certain embodiment, reference may be made to related descriptions of other embodiments.
It will be appreciated that the relevant features of the devices described above may be referred to one another. In addition, "first", "second", and the like in the above embodiments are for distinguishing the embodiments, and do not represent merits of the embodiments.
In the description provided herein, numerous specific details are set forth. However, it is understood that embodiments of the application may be practiced without these specific details. In some instances, well-known structures and techniques have not been shown in detail in order not to obscure an understanding of this description.
Similarly, it should be appreciated that in the foregoing description of exemplary embodiments of the application, various features of the application are sometimes grouped together in a single embodiment, figure, or description thereof for the purpose of streamlining the disclosure and aiding in the understanding of one or more of the various application aspects. However, the disclosed apparatus should not be construed to reflect the intent as follows: this application is intended to cover such departures from the present disclosure as come within known or customary practice in the art to which this invention pertains. Rather, as the following claims reflect, application is directed to less than all features of a single foregoing disclosed embodiment. Thus, the claims following the detailed description are hereby expressly incorporated into this detailed description, with each claim standing on its own as a separate embodiment of this application.
Those skilled in the art will appreciate that the components of the apparatus of the embodiments may be adapted and arranged in one or more arrangements different from the embodiments. The components of the embodiments may be combined into one component and, in addition, they may be divided into a plurality of sub-components. All of the features disclosed in this specification (including any accompanying claims, abstract and drawings), and all of the components of any apparatus so disclosed, may be combined in any combination, except combinations where at least some of such features are mutually exclusive. Each feature disclosed in this specification (including any accompanying claims, abstract and drawings) may be replaced by alternative features serving the same, equivalent or similar purpose, unless expressly stated otherwise.
Furthermore, those skilled in the art will appreciate that while some embodiments described herein include some features included in other embodiments, rather than other features, combinations of features of different embodiments are meant to be within the scope of the application and form different embodiments. For example, in the following claims, any of the claimed embodiments may be used in any combination. The various component embodiments of the present application may be implemented in hardware, or in a combination thereof.
It should be noted that the above-mentioned embodiments illustrate rather than limit the application, and that those skilled in the art will be able to design alternative embodiments without departing from the scope of the appended claims. In the claims, any reference signs placed between parentheses shall not be construed as limiting the claim. The word "comprising" does not exclude the presence of elements or components not listed in a claim. The word "a" or "an" preceding a component or element does not exclude the presence of a plurality of such components or elements. The application can be implemented by means of an apparatus comprising several distinct components. In the claims enumerating several means, several of these means may be embodied by one and the same item. The usage of the words first, second and third, etcetera do not indicate any ordering. These words may be interpreted as names.
The foregoing is a preferred embodiment of the present application, which is not intended to be limiting in any way, and any simple modifications, equivalent variations and modifications made to the foregoing embodiment according to the technical spirit of the present application are within the scope of the present application.

Claims (10)

1. A rapid nucleic acid detection experiment shelter, comprising:
a specimen experiment area;
the separation wall is provided with an operation channel and an article transfer channel which are communicated with the specimen experiment area and the personnel operation area;
the operation part of the operation glove is arranged in a specimen operation area of the specimen experiment area, and the sleeve part of the operation glove is connected to the operation channel;
and the article transfer window is arranged in the article transfer channel.
2. The rapid nucleic acid detection assay shelter of claim 1,
the article transfer window has a first switchable window at a first transfer end thereof, a second switchable window at a second transfer end thereof, and an article placing space between the first switchable window of the transfer window and the second switchable window of the transfer window.
3. The rapid nucleic acid detection assay shelter of claim 2,
and a disinfection ultraviolet lamp is arranged in the article transfer window.
4. The rapid nucleic acid detection assay shelter of claim 1,
the specimen experiment area and the personnel operation area are both negative pressure working areas.
5. The rapid nucleic acid detection assay shelter of claim 4,
the working pressure of the specimen experiment area is less than that of the personnel operation area.
6. The rapid nucleic acid detection assay shelter of claim 1,
the sample experimental area is provided with the outdoor sample transfer passage who is used for delivering the sample of intercommunication, article pass window still set up in sample transfer passage.
7. The rapid nucleic acid detection assay shelter of claim 1,
the specimen experiment area comprises: sample processing and amplification analysis chamber, high pressure sterilization chamber.
8. The rapid nucleic acid detection assay shelter of claim 7,
the operation channel comprises: a first channel communicating the sample processing and amplification analysis chamber with the personnel operating area, a second channel communicating the autoclaving chamber with the personnel operating area;
the operating glove includes: first glove and second glove:
the operating part of the first glove is arranged in the sample processing and amplification analysis area of the sample experiment area, and the sleeve part of the first glove is connected to the first channel;
the operating part of the second glove is arranged in an autoclave area of the specimen experiment area, and the sleeve part of the second glove is connected to the second channel.
9. The rapid nucleic acid detection assay shelter of claim 8,
the article transfer passage includes: a third channel for communicating the sample processing and amplification analysis chamber with the personnel operating area, and a fourth channel for communicating the sample processing and amplification analysis chamber with the autoclave chamber;
the article delivery windows are arranged in the third channel and the fourth channel;
the sample experimental area is also provided with a sample submission channel communicated with the outside;
the article transfer window is also arranged in the specimen submission channel.
10. The rapid nucleic acid testing laboratory shelter of claim 9, further comprising:
the object conveying mechanism is arranged in the sample processing and amplification analysis chamber and is used for conveying the objects conveyed by the object conveying window of the third channel and the samples conveyed by the object conveying window of the sample delivery channel to the area where the operating part of the first glove is located;
the fast nucleic acid detection experiment shelter is 3 meters long, 2.438 meters wide and 2.5 meters high.
CN202120247500.0U 2021-01-28 2021-01-28 Quick nucleic acid detection experiment shelter Active CN214885872U (en)

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Application Number Priority Date Filing Date Title
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Publication Number Publication Date
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115353953A (en) * 2022-09-23 2022-11-18 博尔诚(北京)科技有限公司 Square cabin for health examination

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115353953A (en) * 2022-09-23 2022-11-18 博尔诚(北京)科技有限公司 Square cabin for health examination
CN115353953B (en) * 2022-09-23 2024-04-16 博尔诚(北京)科技有限公司 Shelter for health examination

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Address after: Room 1801, 18 / F, block a, Tsinghua Tongfang science and technology building, 1 Wangzhuang Road, Wudaokou, Haidian District, Beijing 100083

Patentee after: Beijing Tongfang Qinghuan Technology Co.,Ltd.

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Patentee after: Beijing nuclear industry Hospital

Address before: Room 1801, 18 / F, block a, Tsinghua Tongfang science and technology building, 1 Wangzhuang Road, Wudaokou, Haidian District, Beijing 100083

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Country or region before: China

Patentee before: Beijing nuclear industry Hospital