CN213121323U - Immunohistochemical experiment integrated device - Google Patents
Immunohistochemical experiment integrated device Download PDFInfo
- Publication number
- CN213121323U CN213121323U CN202021451942.9U CN202021451942U CN213121323U CN 213121323 U CN213121323 U CN 213121323U CN 202021451942 U CN202021451942 U CN 202021451942U CN 213121323 U CN213121323 U CN 213121323U
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- 238000002474 experimental method Methods 0.000 title claims abstract description 32
- 230000002055 immunohistochemical effect Effects 0.000 title claims abstract description 24
- 238000007789 sealing Methods 0.000 claims abstract description 14
- 239000007788 liquid Substances 0.000 claims description 32
- 239000011521 glass Substances 0.000 claims description 10
- 230000004888 barrier function Effects 0.000 claims description 6
- 230000010354 integration Effects 0.000 claims description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract description 8
- 238000002791 soaking Methods 0.000 description 5
- 238000003364 immunohistochemistry Methods 0.000 description 4
- 239000000427 antigen Substances 0.000 description 3
- 102000036639 antigens Human genes 0.000 description 3
- 108091007433 antigens Proteins 0.000 description 3
- 238000013461 design Methods 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 238000006243 chemical reaction Methods 0.000 description 2
- 238000000151 deposition Methods 0.000 description 2
- 230000012447 hatching Effects 0.000 description 2
- 238000011534 incubation Methods 0.000 description 2
- 230000003834 intracellular effect Effects 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- GNBHRKFJIUUOQI-UHFFFAOYSA-N fluorescein Chemical compound O1C(=O)C2=CC=CC=C2C21C1=CC=C(O)C=C1OC1=CC(O)=CC=C21 GNBHRKFJIUUOQI-UHFFFAOYSA-N 0.000 description 1
- 238000003365 immunocytochemistry Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 229910021645 metal ion Inorganic materials 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 229920001184 polypeptide Polymers 0.000 description 1
- -1 polytetrafluoroethylene Polymers 0.000 description 1
- 239000004810 polytetrafluoroethylene Substances 0.000 description 1
- 229920001343 polytetrafluoroethylene Polymers 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 239000012780 transparent material Substances 0.000 description 1
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Abstract
The utility model relates to an immunohistochemical experiment integrated device, including the base, the top of base is equipped with the main part box, and the main part box is hollow structure, and the top of main part box is equipped with sealed lid, and the inside of main part box sets up a plurality of slide racks of arranging in proper order, and the inside bottom level of main part box is equipped with the plummer, and the slide rack is placed on the plummer. The utility model relates to an immunohistochemical experiment integrated device, it can soak the sample and the sample is hatched the set and go on in a device, has changed and has used too much experimental apparatus in the experiment of current immunohistochemical tissue to reduce experiment operator's complex operation degree. The base is filled with water to form a closed integral structure together with the main body box and the sealing cover, and the water stored in the base rises and disperses into the whole main body box through a through structure gap at the joint of the main body box and the bearing table so as to keep the environment with high humidity in the whole main body box space. The utility model has the advantages of simple structure, various functions and convenient use.
Description
Technical Field
The utility model belongs to the technical field of immunohistochemistry, concretely relates to immunohistochemistry experiment integrated device.
Background
Immunohistochemistry is also called immunocytochemistry, and is a research method for determining tissue intracellular antigens (polypeptides and proteins) by applying the principle of specific combination of antigens and antibodies and developing color development agents (fluorescein, enzyme, metal ions, isotopes and the like) for marking the antibodies through chemical reaction, and carrying out positioning, qualitative and relative quantitative determination on the tissue intracellular antigens.
In immunohistochemistry experiments, the sliced samples need to be dehydrated, cleared, dewaxed, hydrated, incubated with antibodies and other steps, and the samples on the glass slides need to be processed for multiple times, but the existing method needs to manually put each glass slide into different solutions for operation, so that the time, the labor and the resources are wasted, and the existing device is various in type and quantity and inconvenient for operators to operate. The utility model provides an immunohistochemical sample soaks and antibody incubation's integrated device to solve the above-mentioned problem of mentioning.
SUMMERY OF THE UTILITY MODEL
The utility model aims at providing an immunohistochemical experiment integrated device can realize hatching of section sample.
The utility model discloses the technical scheme who adopts is, an immunohistochemical experiment integrated device, including the base, the top of base is equipped with the main part box, and the main part box is upper and lower open hollow structure, and the top of main part box is equipped with sealed lid, and the inside of main part box sets up a plurality of slide racks of arranging in proper order, and the inside bottom level of main part box is equipped with the plummer, and the slide rack is placed on the plummer.
The utility model discloses the characteristics of the technical scheme who adopts do:
the two sides of the bearing platform are fixedly connected with the inner wall of the main body box respectively, and the length of the bearing platform is smaller than that of the bottom surface of the main body box.
The main body box is embedded in the base, and a sealing rubber ring is arranged on one circle of the inner wall of the base.
The slide frame comprises a frame body with an opening at the top and one side, a plurality of U-shaped clamping grooves are sequentially arranged on the inner wall of the frame body from top to bottom, a plurality of bayonets a used for clamping the slides placed in the clamping grooves are sequentially arranged on one side of the opening of the frame body from top to bottom, and the number of the bayonets a is the same as that of the clamping grooves.
The inside round of sealed lid is equipped with the sealing rubber circle.
The inside of main part box still is equipped with the liquid box, and the liquid box is equipped with open-ended cuboid structure for the top, and the liquid box can just be put into to the slide frame.
The inner wall both sides of main part box are equipped with strip blend stop, and the top both ends of liquid box are equipped with bayonet socket b, and liquid box and main part box accessible blend stop and bayonet socket b carry out the joint.
The outer side wall of each liquid box is provided with a label.
The base, the main body case and the sealing cover may form a closed integral structure.
The utility model has the advantages that: the utility model provides an immunohistochemical experiment integrated device, it can soak the sample and the sample is hatched the set and go on in a device, has changed and has used too much experimental apparatus among the current immunohistochemical experiment to reduce experiment operator's complex operation degree. Water is added into the base 1 to form a closed integral structure together with the main body box and the sealing cover, and the water stored in the base rises and disperses into the whole main body box through a through structure gap at the joint of the main body box and the bearing table so as to keep the environment with high humidity in the whole main body box space. The utility model has the advantages of novel design, simple structure, various functions and convenient use.
Drawings
Fig. 1 is a schematic structural diagram of an immunohistochemical experiment integrated device of the present invention;
FIG. 2 is a schematic structural view of the carrier of the present invention;
FIG. 3 is a schematic view of the slide holder according to the present invention;
FIG. 4 is a schematic structural view of the liquid cartridge of the present invention;
fig. 5 is a schematic structural view of an immunohistochemical experiment integration device of the present invention;
FIG. 6 is a schematic structural view of the barrier strip of the present invention;
fig. 7 is a schematic diagram of the structure of the barrier strip and the buckle b of the present invention.
In the figure, the glass slide holder comprises a base 1, a main body box 2, a sealing cover 3, a glass slide holder 4, a holder body 4-1, a clamping groove 4-2, a buckle 4-3, a liquid box 5, a bearing table 6, a retaining strip 7 and a bayonet b 8.
Detailed Description
The present invention will be described in detail with reference to the accompanying drawings and specific embodiments.
As shown in fig. 1, for the utility model relates to a structure schematic diagram of immunohistochemical experiment integrated device, including base 1, base 1's top is equipped with main part box 2, main part box 2 is upper and lower open hollow structure, main part box 2 is embedded on base 1, main part box 2's top is equipped with sealed lid 3, main part box 2's inside sets up a plurality of slide racks 4 of arranging in proper order, as shown in fig. 2, main part box 2's inside bottom level is equipped with plummer 6, slide rack 4 is placed on plummer 6, plummer 6's both sides respectively with main part box 2's inner wall rigid coupling, plummer 6's length is less than the length of main part box 2 bottom surface, can make the vapor flow of the water of depositing in the base 1 to slide rack 4 departments, thereby guarantee that hollow structure keeps a comparatively moist environment in the main part box 2, be favorable to going on of experiment.
As shown in FIG. 3, the slide rack 4 comprises a rack body 4-1 with an opening at the top and one side, a plurality of U-shaped clamping grooves 4-2 are sequentially arranged on the inner wall of the rack body 4-1 from top to bottom, a plurality of bayonets a4-3 for clamping slides placed in the clamping grooves 4-2 are sequentially arranged on the opening side of the rack body 4-1 from top to bottom, the number of the bayonets a4-3 is the same as that of the clamping grooves 4-2, when a slicing sample experiment is carried out, the slides are inserted into the clamping grooves of the rack body 1, and the slides are fixed through the bayonets a 4-3.
The utility model discloses in the device, except that slide frame 4 chooseed for use stainless steel material, polytetrafluoroethylene transparent material was all chooseed for use to other structures, and the outer wall scribbles opaque coating.
The inner wall round of base 1 is equipped with the sealing rubber circle, the inside round of sealed lid 3 is equipped with the sealing rubber circle, the top and the sealed 3 sealed gomphosis of sealed lid of main part box 2, the bottom and the sealed gomphosis of base 1 of main part box 2, add water and main part box 2 and sealed 3 formation inclosed overall structure toward base 1, the water of depositing in the base 1 rises by the penetrating structure clearance of main part box 2 and 6 junctions of plummer and disperses to whole main part box 2 in, in order to keep the environment of the high humidity in whole main part box 2 space.
The outer side wall of the liquid cartridge 5 is provided with a label for indicating the nature of the liquid in the liquid cartridge.
The utility model discloses a working process does: when the sample needs to soak, with base 1 and 2 gomphosis of main part box, can confirm according to the experiment requirement that add not add water in the base 1, place the slide in slide frame 4 and place slide frame 4 in liquid box 5, the liquid that needs to soak is placed in liquid box 5, bayonet socket b8 card through liquid box 5 is in main part box 2, put into No. 5 liquid boxes with bayonet socket 8 is last and the mode of putting of perpendicular to bottom surface, and add the required liquid of experiment, constitute the mode of soaking jointly, and can place in the main part box 2 that a plurality of liquid boxes can add different liquid and be used for the soaking reaction of slide.
When the sample requires antibody incubation, the base 1 is engaged with the box-like hollow main body case 2. After the glass slide is taken out of the glass slide rack 4 and the antibody is dripped, the glass slide rack 4 is put back and put on the platform 6 in the main body box 2 in a way of being parallel to the bottom surface, and then the sealing cover 1 is embedded with the main body box 2 to ensure the tightness.
The utility model discloses wet box, slide frame, immunohistochemical instrument such as soaking with glass jar that the device used in through the integrated immunohistochemical chemistry experiment simplify the experimental procedure, improve experimental efficiency. Synthesize above-mentioned circumstances and know, through above-mentioned structural design, the utility model has the advantages of novel in design, simple structure, various, the convenient to use of function.
Claims (9)
1. The utility model provides an immunohistochemical experiment integrated device, its characterized in that, includes base (1), and the top of base is equipped with main part box (2), main part box (2) are open hollow structure from top to bottom, and the top of main part box (2) is equipped with sealed lid (3), the inside of main part box (2) sets up a plurality of slide racks (4) of arranging in proper order, the inside bottom level of main part box (2) is equipped with plummer (6), and slide rack (4) are placed on plummer (6).
2. The integrated device for the immunohistochemical experiment according to claim 1, wherein two sides of the bearing table (6) are fixedly connected with the inner wall of the main body box (2), and the length of the bearing table (6) is smaller than the length of the bottom surface of the main body box (2).
3. The integrated device for the immunohistochemical experiment according to claim 1, wherein the bottom of the main body box (2) is embedded in the base (1), and a sealing rubber ring is arranged around the inner wall of the base (1).
4. The integrated device for the immunohistochemical experiment according to claim 1, wherein the slide holder (4) comprises a holder body (4-1) with an opening at the top and one side, the inner wall of the holder body (4-1) is sequentially provided with a plurality of U-shaped clamping grooves (4-2) from top to bottom, the opening one side of the holder body (4-1) is sequentially provided with a plurality of bayonets a (4-3) from top to bottom, the bayonets a (4-3) are used for clamping the slide glass placed in the clamping grooves (4-2), and the number of the bayonets a (4-3) is the same as the number of the clamping grooves (4-2).
5. The integrated device for the immunohistochemical experiment according to claim 1, wherein the top of the main body box (2) is embedded in the sealing cover (3), and the sealing rubber ring is arranged around the inside of the sealing cover (3).
6. The integrated device for the immunohistochemical experiment according to claim 1, wherein the main body box (2) is further provided with a liquid box (5), the liquid box (5) is of a cuboid structure with an opening at the top, and the slide holder (4) can be just placed in the liquid box (5).
7. The integrated device for the immunohistochemical experiment according to claim 6, wherein two sides of the inner wall of the main body box (2) are provided with strip-shaped barrier strips (7), two ends of the top of the liquid box (5) are provided with bayonets b (8), and the liquid box (5) and the main body box (2) can be clamped through the barrier strips (7) and the bayonets b (8).
8. An immunohistochemical experiment integration device according to claim 6, wherein the outer sidewall of each liquid cartridge (5) is provided with a label.
9. The integrated device for immunohistochemical experiments according to any one of claims 1 to 8, wherein the base (1), the main body case (2) and the sealing cover (3) form a closed integral structure.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202021451942.9U CN213121323U (en) | 2020-07-22 | 2020-07-22 | Immunohistochemical experiment integrated device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202021451942.9U CN213121323U (en) | 2020-07-22 | 2020-07-22 | Immunohistochemical experiment integrated device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN213121323U true CN213121323U (en) | 2021-05-04 |
Family
ID=75678619
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202021451942.9U Expired - Fee Related CN213121323U (en) | 2020-07-22 | 2020-07-22 | Immunohistochemical experiment integrated device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN213121323U (en) |
-
2020
- 2020-07-22 CN CN202021451942.9U patent/CN213121323U/en not_active Expired - Fee Related
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| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20210504 |