CN213068887U - Sample analyzer, liquid adding device and reagent replacing device - Google Patents
Sample analyzer, liquid adding device and reagent replacing device Download PDFInfo
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- CN213068887U CN213068887U CN202020929528.8U CN202020929528U CN213068887U CN 213068887 U CN213068887 U CN 213068887U CN 202020929528 U CN202020929528 U CN 202020929528U CN 213068887 U CN213068887 U CN 213068887U
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Abstract
The utility model provides a sample analyzer, a liquid feeding device and a reagent replacing device, wherein, the reagent replacing device comprises a detector and a pressure source; the detector is used for detecting whether the liquid supply pipeline is in a normal liquid supply state or an abnormal liquid supply state; a pressure source in communication with the supply line downstream of the detector; when the detector detects that the liquid supply pipeline is in an abnormal liquid supply state, the pressure source starts to provide negative pressure to drain the liquid supply pipeline and stops providing the negative pressure after keeping the preset time. The utility model provides a negative pressure that sample analysis appearance, liquid feeding device, reagent change device provided through the pressure source when changing reagent carries out the drainage, can avoid using the syringe to take out repeatedly and push away inefficiency and produce the problem of more bubble.
Description
Technical Field
The utility model relates to a medical treatment detection and analysis technical field, concretely relates to device is changed to sample analysis appearance, liquid feeding device, reagent.
Background
In a blood cell analyzer, changing a reagent is a frequent operation in which the reagent is sucked into a syringe/diaphragm pump and then discharged from the syringe/diaphragm pump. This replacement causes the following problems: (1) because the reagent needs to enter the injector from the reagent bottle and the reagent injector needs to be repeatedly pushed and pulled for many times when being replaced, bubbles in the reagent are greatly increased, and the detection precision is further influenced; (2) in this way, the reagent needs to pass through all the pipelines, which results in the waste of the reagent.
SUMMERY OF THE UTILITY MODEL
The utility model provides a device is changed to sample analysis appearance, liquid feeding device, reagent to can produce the technical problem of a large amount of bubbles when changing reagent among the solution prior art.
In order to solve the technical problem, the utility model discloses a technical scheme be: providing a reagent replacement device comprising a detector, a pressure source;
the detector is used for detecting whether the liquid supply pipeline is in a normal liquid supply state or an abnormal liquid supply state;
the pressure source is in communication with the supply line downstream of the detector;
when the detector detects that the liquid supply pipeline is in an abnormal liquid supply state, the pressure source starts to provide negative pressure to drain the liquid supply pipeline and stops providing the negative pressure after the preset time is kept.
According to the utility model relates to a specific embodiment, the detector is light even sensor, light even sensor sets up on the route of liquid supply pipeline, through the voltage variation that light even sensor detected judges for normal confession liquid state or unusual confession liquid state in the liquid supply pipeline.
According to the utility model discloses a specific embodiment, the light couple sensor sets up the one end that the route of confession liquid pipeline is close to the reagent bottle, the pressure source is in access point on the confession liquid pipeline is close to the light couple sensor.
According to the utility model discloses a specific embodiment, the reagent is changed the device and is still included three way connection, three way connection's first end with the pressure source intercommunication, three way connection's second end and third end are established ties in the liquid supply pipeline.
According to the utility model discloses a specific embodiment, three way connection's first end with be equipped with the drainage pipeline between the pressure source, be connected with the on-off valve in the drainage pipeline.
For solving the technical problem, the utility model discloses a another technical scheme is: the utility model provides a liquid feeding device, liquid feeding device includes gating valve, public pipeline, supplies liquid pipeline, pushes away liquid pipeline, suction device, detector, pressure source, wherein:
the common pipeline connects the suction device with the option valve;
the liquid supply pipeline is connected with the selective valve;
the liquid pushing pipeline is connected with the selective valve;
the suction device is used for sucking liquid through the public pipeline, the option valve and the liquid supply pipeline;
the suction device is also used for pushing liquid through the public pipeline, the selective valve and the liquid pushing pipeline;
the detector is used for detecting whether the liquid supply pipeline is in a normal liquid supply state or an abnormal liquid supply state;
the pressure source is in communication with the supply line downstream of the detector;
when the detector detects that the liquid supply pipeline is in an abnormal liquid supply state, the pressure source starts to provide negative pressure to drain the liquid supply pipeline and stops providing the negative pressure after the preset time is kept.
According to the utility model relates to a specific embodiment, the liquid feeding device still includes three way connection, three way connection's first end with the pressure source intercommunication, three way connection's second end and third end are established ties and are in the liquid supply pipeline, three way connection's first end with be equipped with the drainage pipeline between the pressure source, be connected with the on-off valve in the drainage pipeline.
For solving the technical problem, the utility model discloses a another technical scheme is: there is provided a sample analyzer comprising the aforementioned reagent replacement device or the aforementioned liquid charging device.
The utility model has the advantages that: be different from prior art's condition, the utility model provides a negative pressure that device was changed to sample analysis appearance, liquid feeding device, reagent provided through the pressure source carries out the drainage when changing reagent, can avoid using the syringe to take out repeatedly and push away the problem of inefficiency and production more bubble.
Drawings
In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the drawings used in the description of the embodiments will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and other drawings can be obtained by those skilled in the art without inventive efforts, wherein:
FIG. 1 is a simplified schematic diagram of a liquid circuit according to an embodiment of the liquid adding device provided by the present invention;
fig. 2 is a simplified schematic diagram of a liquid path of another embodiment of the liquid adding device provided by the present invention.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work all belong to the protection scope of the present invention.
It should be noted that, if directional indications (such as upper, lower, left, right, front and rear … …) are involved in the embodiment of the present invention, the directional indications are only used to explain the relative position relationship between the components, the motion situation, etc. in a specific posture (as shown in the drawings), and if the specific posture is changed, the directional indications are changed accordingly.
In addition, if there is a description relating to "first", "second", etc. in the embodiments of the present invention, the description of "first", "second", etc. is for descriptive purposes only and is not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one such feature. In addition, the technical solutions in the embodiments may be combined with each other, but it must be based on the realization of those skilled in the art, and when the technical solutions are contradictory or cannot be realized, the combination of the technical solutions should not be considered to exist, and is not within the protection scope of the present invention.
Referring to fig. 1, an embodiment of the present invention provides a reagent replacement device, which includes a detector 210 and a pressure source 220.
The detector 210 is used to detect a normal liquid supply state or an abnormal liquid supply state in the liquid supply pipeline 120, where the normal liquid supply state refers to a state in which the liquid supply pipeline 120 is filled with continuous liquid, and the abnormal liquid supply state refers to a state in which the liquid supply pipeline 120 is not filled with continuous liquid, that is, a state in which the liquid in the liquid supply pipeline 120 is mixed with more bubbles or is completely air. Wherein, the one end and the reagent bottle 150 of feed pipeline 120 are pegged graft for absorb the reagent in the reagent bottle 150, the kind of reagent does not do the restriction, and all detect reagent (like hemolytic agent, antibody reagent), diluent, cleaning solution etc. that need use and all be suitable for the utility model provides a device is changed to reagent.
A pressure source 220 communicates with the supply line 120 downstream of the detector 210. The pressure source 220 may be a negative pressure source, which can continuously and stably provide negative pressure to rapidly exhaust air in the liquid supply pipeline 120 at one time, thereby avoiding the use of an injector that is repeatedly pushed and pulled, which is inefficient and generates more bubbles. Moreover, when the negative pressure source is used for reagent replacement, the reagent can be replaced only through the liquid supply pipeline 120, and reagent waste is relatively reduced compared with the situation that the reagent needs to pass through all pipelines when the injector is used for repeatedly pushing and pulling the reagent in a reciprocating manner.
When the detector 210 detects an abnormal liquid supply state in the liquid supply line 120, the pressure source 220 starts to provide negative pressure to drain the liquid supply line 120 and stops providing negative pressure after keeping for a predetermined time. Wherein the predetermined time may be calculated based on the volume of the supply line 120 and the rate at which the pressure source 220 is draining.
In order to realize the reagent replacement without stopping the machine, the other pipelines except the liquid supply pipeline 120 can be designed to have larger volume, and the normal liquid conveying work and the reagent replacement operation can be synchronously carried out.
The detector 210 may be a photo-couple sensor disposed on a path of the liquid supply line 120, and determines whether the liquid supply line 120 is in a normal liquid supply state or an abnormal liquid supply state according to a voltage variation detected by the photo-couple sensor. When the liquid supply pipe 120 is in a normal liquid supply state, the voltage is relatively stable, and when the liquid supply pipe 120 is in an abnormal liquid supply state, the voltage is significantly fluctuated.
The thermocouple sensor may be disposed at an end of the supply line 120 near the reagent bottle 150 to detect the reagent exhaustion in time and send out a warning signal to remind the user to replace the reagent, and the access point of the pressure source 220 on the supply line 120 is close to the thermocouple sensor to rapidly discharge the air bubbles in the supply line 120 in time and pertinence.
Specifically, the reagent changing device further includes a three-way joint 230, a first end of the three-way joint 230 is communicated with the pressure source 220, and a second end and a third end of the three-way joint 230 are connected in series in the liquid supply line 120.
A drainage pipeline 240 is arranged between the first end of the three-way joint 230 and the pressure source 220, an on-off valve 250 is connected in the drainage pipeline 240, and the on-off valve 250 performs on-off action according to a control signal sent by the main control unit.
Referring to fig. 1, the present invention further provides a liquid adding device, which includes a selector valve 100, a common pipe 110, a liquid supply pipe 120, a liquid pushing pipe 130, a suction device 140, a detector 210, and a pressure source 220.
The common line 110 connects the suction device 140 with the gate valve 100; the liquid supply pipeline 120 is connected with the selective valve 100; the liquid pushing pipeline 130 is connected with the selective valve 100; when the reagent is normally used, the suction device 140 is used for sucking liquid through the public pipeline 110, the gate valve 100 and the liquid supply pipeline 120; the suction device 140 is also used for pushing liquid through the common pipe 110, the gate valve 100 and the liquid pushing pipe 130. The suction device 140 may be a syringe, a constant flow pump, or a diaphragm pump.
The detector 210 is used to detect a normal liquid supply state or an abnormal liquid supply state in the liquid supply pipeline 120, where the normal liquid supply state refers to a state in which the liquid supply pipeline 120 is filled with continuous liquid, and the abnormal liquid supply state refers to a state in which the liquid supply pipeline 120 is not filled with continuous liquid, that is, a state in which the liquid in the liquid supply pipeline 120 is mixed with more bubbles or is completely air. One end and the reagent bottle 150 of confession liquid pipeline 120 peg graft for absorb the reagent in the reagent bottle 150, the kind of reagent does not do the restriction, and all detect need be used reagent (like hemolytic agent, antibody reagent), diluent, cleaning solution etc. and all be suitable for the utility model provides a liquid feeding device.
A pressure source 220 communicates with the supply line 120 downstream of the detector 210. The pressure source 220 may be a negative pressure source, which can continuously and stably provide negative pressure to rapidly exhaust air in the liquid supply pipeline 120 at one time, thereby avoiding the use of an injector that is repeatedly pushed and pulled, which is inefficient and generates more bubbles. Moreover, when the negative pressure source is used for reagent replacement, the reagent can be replaced only through the liquid supply pipeline 120, and reagent waste is relatively reduced compared with the situation that the reagent needs to pass through all pipelines when the injector is used for repeatedly pushing and pulling the reagent in a reciprocating manner.
When the detector 210 detects an abnormal liquid supply state in the liquid supply line 120, the pressure source 220 starts to supply negative pressure to drain the liquid supply line 120 and stops supplying negative pressure after a predetermined time. Wherein the predetermined time may be calculated based on the volume of the supply line 120 and the rate at which the pressure source 220 is draining.
In order to realize the reagent replacement without stopping the machine, the other pipelines except the liquid supply pipeline 120 can be designed to have larger volume, and the normal liquid conveying work and the reagent replacement operation can be synchronously carried out.
The detector 210 may be a photo-couple sensor disposed on a path of the liquid supply line 120, and determines whether the liquid supply line 120 is in a normal liquid supply state or an abnormal liquid supply state according to a voltage variation detected by the photo-couple sensor. When the liquid supply pipe 120 is in a normal liquid supply state, the voltage is relatively stable, and when the liquid supply pipe 120 is in an abnormal liquid supply state, the voltage is significantly fluctuated.
The optical couple sensor is disposed at an end of the path of the liquid supply line 120 close to the reagent bottle 150 so as to detect the reagent exhaustion in time and send out a warning signal to remind the user to replace the reagent, and the access point of the pressure source 220 on the liquid supply line 120 is close to the optical couple sensor so as to rapidly discharge the air bubbles in the liquid supply line 120 in a timely and targeted manner.
The liquid adding device further comprises a three-way joint 230, a first end of the three-way joint 230 is communicated with the pressure source 220, a second end and a third end of the three-way joint 230 are connected in series in the liquid supply pipeline 120, a drainage pipeline 240 is arranged between the first end of the three-way joint 230 and the pressure source 220, an on-off valve 250 is connected in the drainage pipeline 240, and the on-off valve 250 performs on-off action according to a control signal sent by the main control unit.
Referring to fig. 2, the present embodiment is substantially the same as the embodiment shown in fig. 1, except that the selector valve 100, the common line 110, the liquid supply line 120, the liquid pushing line 130, the pumping device 140, the reagent bottle 150, the detector 210, the three-way joint 230, the drainage line 240, and the on-off valve 250 may be two or more sets and the pressure source 220 is multiplexed through the confluence joint 242.
The utility model also provides a sample analyzer, this sample analyzer include aforementioned reagent change device or aforementioned liquid feeding device.
In conclusion, the technical person in the art understands easily, the utility model provides a negative pressure that sample analyzer, liquid feeding device, reagent change device provided through pressure source 220 when changing reagent carries out the drainage, can avoid using the syringe to take out repeatedly and push away the problem of inefficiency and production more bubble, can realize the operation of changing reagent not shutting down, promotes detection efficiency, and reagent when reducible reagent changes is extravagant simultaneously.
The above is only the embodiment of the present invention, not the limitation of the patent scope of the present invention, all the equivalent structures or equivalent processes that are used in the specification and the attached drawings or directly or indirectly applied to other related technical fields are included in the patent protection scope of the present invention.
Claims (10)
1. A reagent replacement device, comprising a detector, a pressure source;
the detector is used for detecting whether the liquid supply pipeline is in a normal liquid supply state or an abnormal liquid supply state;
the pressure source is in communication with the supply line downstream of the detector;
when the detector detects that the liquid supply pipeline is in an abnormal liquid supply state, the pressure source starts to provide negative pressure to drain the liquid supply pipeline and stops providing the negative pressure after the preset time is kept.
2. The reagent changing device of claim 1,
the detector is a light couple sensor which is arranged on a path of the liquid supply pipeline, and the normal liquid supply state or the abnormal liquid supply state in the liquid supply pipeline is judged according to the voltage change detected by the light couple sensor.
3. The reagent changing device of claim 2, wherein the optical sensor is disposed at an end of the path of the liquid supply line near the reagent bottle, and the access point of the pressure source on the liquid supply line is near the optical sensor.
4. The reagent replacement device of claim 1 further comprising a tee, a first end of the tee being in communication with the pressure source, a second end and a third end of the tee being connected in series in the fluid supply line.
5. The reagent changing device of claim 4, wherein a drain line is disposed between the first end of the tee and the pressure source, and an on-off valve is connected to the drain line.
6. The utility model provides a liquid feeding device, its characterized in that, liquid feeding device includes gate valve, public pipeline, supplies liquid pipeline, pushes away liquid pipeline, suction device, detector, pressure source, wherein:
the common pipeline connects the suction device with the option valve;
the liquid supply pipeline is connected with the selective valve;
the liquid pushing pipeline is connected with the selective valve;
the suction device is used for sucking liquid through the public pipeline, the option valve and the liquid supply pipeline;
the suction device is also used for pushing liquid through the public pipeline, the selective valve and the liquid pushing pipeline;
the detector is used for detecting whether the liquid supply pipeline is in a normal liquid supply state or an abnormal liquid supply state;
the pressure source is in communication with the supply line downstream of the detector;
when the detector detects that the liquid supply pipeline is in an abnormal liquid supply state, the pressure source starts to provide negative pressure to drain the liquid supply pipeline and stops providing the negative pressure after the preset time is kept.
7. The filling device according to claim 6,
the detector is a light couple sensor which is arranged on a path of the liquid supply pipeline, and the normal liquid supply state or the abnormal liquid supply state in the liquid supply pipeline is judged according to the voltage change detected by the light couple sensor.
8. The charging device according to claim 7, wherein said light couple detector is disposed at an end of the path of said liquid supply line near the reagent bottle, and the access point of said pressure source on said liquid supply line is near said light couple sensor.
9. The liquid adding device according to claim 6, further comprising a tee joint, wherein a first end of the tee joint is communicated with the pressure source, a second end and a third end of the tee joint are connected in series in the liquid supply pipeline, a drainage pipeline is arranged between the first end of the tee joint and the pressure source, and an on-off valve is connected in the drainage pipeline.
10. A sample analyser comprising a reagent exchange device according to any one of claims 1 to 5 or a charging device according to any one of claims 6 to 9.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202020929528.8U CN213068887U (en) | 2020-05-27 | 2020-05-27 | Sample analyzer, liquid adding device and reagent replacing device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202020929528.8U CN213068887U (en) | 2020-05-27 | 2020-05-27 | Sample analyzer, liquid adding device and reagent replacing device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN213068887U true CN213068887U (en) | 2021-04-27 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202020929528.8U Active CN213068887U (en) | 2020-05-27 | 2020-05-27 | Sample analyzer, liquid adding device and reagent replacing device |
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| Country | Link |
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| CN (1) | CN213068887U (en) |
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- 2020-05-27 CN CN202020929528.8U patent/CN213068887U/en active Active
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