CN212894721U - Sample collection device - Google Patents

Sample collection device Download PDF

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Publication number
CN212894721U
CN212894721U CN202021255351.4U CN202021255351U CN212894721U CN 212894721 U CN212894721 U CN 212894721U CN 202021255351 U CN202021255351 U CN 202021255351U CN 212894721 U CN212894721 U CN 212894721U
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sampling
specimen
cavity
piece
collection device
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CN202021255351.4U
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梁丽萍
刘乐
陈烨
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Southern Hospital Southern Medical University
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Southern Hospital Southern Medical University
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Abstract

The utility model discloses a specimen collecting device, which comprises a collecting container, wherein a liquid storage cavity and a specimen cavity are arranged in the collecting container, the liquid storage cavity and the specimen cavity are separated by a spacing structure, and the spacing structure comprises a rupturable interlayer under the action of external force; the collector comprises a sampling piece and a detachable first cover body, the sampling piece comprises a first sampling piece, the first end of the first sampling piece is fixed on the first cover body, and the second end of the first sampling piece can extend into the specimen cavity and break the interlayer. The utility model discloses a set up sample chamber and stock solution chamber in collecting container, insert the sample chamber after the first sampling piece on the collector adopts, both can put into the sample chamber with the sample, also can make the interlayer break to stock solution chamber and sample chamber intercommunication, the protection liquid in the stock solution chamber flows into the sample chamber, behind the tight first lid of lid, can realize the good save to the sample. The utility model discloses simplify operating procedure, with the collection, mixing and the save integration of sample, improved clinical work efficiency.

Description

Sample collection device
Technical Field
The utility model relates to a specimen collecting device in the technical field of medical instruments.
Background
With the continuous development of sequencing analysis technology, the importance of the intestinal flora in the occurrence and development of diseases is gradually revealed. Sequencing analysis of intestinal flora needs to be based on high quality fecal nucleic acid extraction. However, there is no recognized and effective feces collection device and standardized process. The current method commonly used in clinic is to scrape a proper amount of excrement by using a sampling spoon in a simple excrement collection box and then place the excrement in the collection box. The method needs the patient to send the stool sample to the clinical detection laboratory for related operations such as separation culture or microorganism nucleic acid extraction or cryopreservation within a certain period of time, and is not beneficial to follow-up of outpatient chronic disease patients. The feces contain a large amount of biological enzymes (such as DNase and RNase), and DNA and RNA of bacteria in the feces specimen are easily degraded at room temperature, so that the nucleic acid extraction effect is poor; in addition, the stool specimen also contains a large amount of dietary fibers, food residues and other impurities, which affect the efficiency of subsequent nucleic acid extraction. Therefore, it is very important to design a stool collection device capable of storing and filtering the stool specimen at normal temperature.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to solve one of the technical problem that exists among the prior art at least, provide a sample collection system, it can gather and well preserve the sample.
According to a first aspect of the present invention, there is provided a specimen collecting device, which includes a collecting container having an opening, a liquid storage cavity and a specimen cavity are provided in the collecting container, the opening is communicated with the specimen cavity, the liquid storage cavity is separated from the specimen cavity by a spacing structure, the spacing structure includes a rupturable separation layer under an external force; the collector comprises a sampling piece and a detachable first cover body, the first cover body is used for covering the opening, the sampling piece comprises a first sampling piece, the first end of the first sampling piece is fixed on the first cover body, and the second end of the first sampling piece can extend into the specimen cavity and enable the interlayer to be broken.
According to the utility model discloses first aspect embodiment, furtherly, the stock solution chamber surrounds the side and the bottom surface in specimen chamber, interval structure still includes the partition wall, the side in specimen chamber is passed through the partition wall with stock solution chamber interval, the underrun in specimen chamber the partition wall with stock solution chamber interval.
According to the utility model discloses first aspect embodiment, further, the outside of stock solution chamber is equipped with the outflow passageway that can open and close.
According to the utility model discloses in the embodiment of the first aspect, furtherly, the outflow passageway is located on the bottom surface of stock solution chamber, the bottom of collector is equipped with deformable supporting part, the bottom surface of outflow passageway flush or cave in the bottom surface before the supporting part warp, the bottom surface salient of outflow passageway in the bottom surface after the supporting part warp.
According to an embodiment of the first aspect of the present invention, the outflow channel further comprises an outflow opening and a second cover for covering the outflow opening, wherein a filter is disposed on the outflow opening.
According to the utility model discloses the embodiment of the first aspect, furtherly, be connected with detachable card firmware on the lateral wall of first end of first sampling spare, be equipped with fixing hole on the first lid, first sampling spare runs through fixing hole, first sampling spare with fixing hole seals the cooperation, card firmware butt is in first lid is kept away from on the terminal surface of collecting vessel.
According to the utility model discloses the embodiment of the first aspect, furtherly, be equipped with the external screw thread on the lateral wall of first sampling spare, the card firmware is equipped with the internal thread, first sampling spare and card firmware threaded connection.
According to the utility model discloses first aspect embodiment, furtherly, sampling piece still includes second sampling piece, first sampling piece is the burette, the second end of burette is most advanced, second sampling piece is the sampling spoon.
According to the utility model discloses in the embodiment of the first aspect, further, first lid with collection container threaded connection, first lid with be equipped with first sealing member between the collection container.
The utility model has the advantages that: the utility model discloses a set up sample chamber and stock solution chamber in collecting container, insert the sample chamber after the first sampling piece on the collector adopts, both can put into the sample chamber with the sample, also can make the interlayer break to stock solution chamber and sample chamber intercommunication, the protection liquid in the stock solution chamber flows into the sample chamber, behind the tight first lid of lid, can realize the good save to the sample. The utility model discloses simplify operating procedure, with the collection, mixing and the save integration of sample, improved clinical work efficiency.
Drawings
In order to more clearly illustrate the technical solution in the embodiments of the present invention, the drawings used in the description of the embodiments will be briefly described below. It is clear that the described figures represent only some embodiments of the invention, not all embodiments, and that a person skilled in the art can also derive other designs and figures from these figures without inventive effort.
Fig. 1 is a schematic view of the assembled structure of the present invention (with the interlayer intact);
fig. 2 is a schematic view of the assembled structure of the present invention (interlayer broken state).
Detailed Description
This section will describe in detail the embodiments of the present invention, preferred embodiments of the present invention are shown in the attached drawings, which are used to supplement the description of the text part of the specification with figures, so that one can intuitively and vividly understand each technical feature and the whole technical solution of the present invention, but they cannot be understood as the limitation of the protection scope of the present invention.
In the description of the present invention, it should be understood that the orientation or positional relationship indicated with respect to the orientation description, such as up, down, front, rear, left, right, etc., is based on the orientation or positional relationship shown in the drawings, and is only for convenience of description and simplification of description, and does not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus, should not be construed as limiting the present invention.
In the description of the present invention, a plurality of means are one or more, a plurality of means are two or more, and the terms greater than, less than, exceeding, etc. are understood as not including the number, and the terms greater than, less than, within, etc. are understood as including the number. If the first and second are described for the purpose of distinguishing technical features, they are not to be understood as indicating or implying relative importance or implicitly indicating the number of technical features indicated or implicitly indicating the precedence of the technical features indicated.
In the description of the present invention, unless there is an explicit limitation, the words such as setting, installation, connection, etc. should be understood in a broad sense, and those skilled in the art can reasonably determine the specific meanings of the above words in combination with the specific contents of the technical solution.
Referring to fig. 1-2, a specimen collection device according to an embodiment of the present invention includes a collection container 1 and a collector 2.
Collecting container 1 has the opening, is equipped with stock solution chamber 11 and sample chamber 13 in the collecting container 1, opening and sample chamber 13 intercommunication, separate through interval structure between stock solution chamber 11 and the sample chamber 13, and interval structure includes the interlayer 12 that can break down under the exogenic action, and optionally, interlayer 12 is the plastics diaphragm. In this embodiment, the liquid storage cavity 11 surrounds the side and the bottom of the specimen cavity 13, the spacing structure further includes a partition wall, the side of the specimen cavity 13 is separated from the liquid storage cavity 11 by the partition wall, and the bottom of the specimen cavity 13 is separated from the liquid storage cavity 11 by the partition wall 12. The liquid storage cavity is used for storing protective liquid 111 capable of protecting the specimen, and the partition wall is a hard plastic component and can be made of the same material as the collecting container, so that the protective liquid 111 in the liquid storage cavity 11 is prevented from being mixed into the specimen cavity 13 due to the rupture of the partition wall. Because the interlayer 12 is located on the bottom surface of the specimen cavity 13, as long as the liquid level of the protection liquid in the liquid storage cavity 11 is higher than the horizontal position of the interlayer 12 before the interlayer 12 is broken, the protection liquid 111 can flow into the specimen cavity 13 under the action of gravity after the interlayer 12 is broken until the liquid level in the specimen cavity 13 is flush with the liquid level of the liquid storage cavity 11, the sufficient protection liquid 111 can better protect the specimen, and the situation that the amount of the protection liquid 111 is insufficient to protect the specimen is avoided.
The collector 2 comprises a sampling member and a detachable first cover 23, the first cover 23 being adapted to cover the opening. Optionally, the first cover 23 is provided with a threaded groove 233, the top end of the collection container 1 is provided with an outer wall thread 14, and the first cover 23 is in threaded connection with the collection container 1. In order to ensure that the specimen in the collection container 1 does not leak, a first sealing member 231 is disposed between the first cover 23 and the collection container 1, and the first sealing member 231 may be a sealing rubber ring.
The sampling member comprises a first sampling member, a first end of which is fixed to the first cover 23, and a second end of which is extendable into the specimen chamber 13 and can rupture the barrier 12. In this embodiment, the first sampling member is a dip tube 21, and in order to better rupture the barrier 12, the second end of the dip tube 21 is a beveled tip 214. Because the second end of the dropper 21 is the bevel tip 214, the puncture barrier 12 can be easily punctured, and the contact area of the dropper 21 and the liquid sample can be increased, so that the sampling is convenient. The sampling part further comprises a second sampling part which is a sampling spoon 22, and preferably, the spoon mouth of the sampling spoon 22 faces away from the dropper 21, so that the dropper 21 is prevented from blocking the sampling spoon. Of course, the first sampling member is not limited to the dropper 21, but may be a sampling tool such as a sampling spoon; accordingly, when the first sampling member is a sampling spoon, the second sampling member may be a dropper. An indicator line 215 may be provided on the dropper 21 to determine the amount of specimen collected, and to try to collect it quantitatively.
To protect the barrier 12 from damage when the protective liquid 111 is not introduced into the sample chamber 13, a fastener 24 is provided to protect the barrier 12. The clamping member 24 is detachably connected to a side wall of a first end of the first sampling member, the first cover body 23 is provided with a fixing through hole, the first sampling member penetrates through the fixing through hole, the first sampling member is in sealing fit with the fixing through hole, and the clamping member 24 abuts against an end face, away from the collecting container 1, of the first cover body 23. Alternatively, the fastening member 24 is ring-shaped, and the inner wall of the fastening member 24 is provided with an internal thread. Dropper 21 includes a dropper cap 211 and a dropper body 212, it being apparent that dropper cap 211 is located at a first end of dropper 21. Correspondingly, the dropping pipe body 212 is provided with an external thread 213 on the side wall of one end close to the dropping pipe cap 211, and the dropping pipe body 212 is threaded with the annular clamping piece 24 after penetrating through the clamping piece. Note that the minimum vertical distance between the inclined tip 214 of the dropper 21 and the barrier 12 in the collecting device after assembly and before use is d, and d should be smaller than the height of the fastening member 24 so that the dropper 21 disconnected from the fastening member 24 can pierce the barrier 12.
Furthermore, the fixing through hole is provided with a through hole internal thread 234, and after the fastening member 24 is removed, the dropper body 212 can still be fixed on the first cover 23 by the matching of the external thread 213 and the through hole internal thread 234. Preferably, a second sealing member 232 is provided below the fixing through-hole to prevent the specimen and the protective solution from leaking through the fixing through-hole. The second sealing element 232 may be a sealing rubber ring, and the drop tube body 212 penetrates through the second sealing element 232 and is in interference fit with the second sealing element 232, so as to achieve the effect of sealing and leakage prevention.
After the bevel tip 214 of the dropper 21 pierces the partition 12 and the protective liquid 111 is mixed with the specimen, a liquid sample containing the specimen is obtained. An openable and closable outflow channel 16 is provided on the outside of the reservoir chamber 11. Specifically, the outflow channel 16 is located on the bottom surface of the reservoir chamber 11, and the outflow channel 16 includes an outflow port on which a filter 161 is provided, and a second cover 17 for covering the outflow port. After the second lid 17 is opened, the liquid containing the specimen can be poured out. In the embodiment, the sample is feces, so that the filter can effectively filter part of impurities, so that high-concentration bacteria liquid can be collected conveniently, and development of subsequent research projects is facilitated.
Preferably, the bottom of the collector 2 is provided with a deformable support 15, the bottom surface of the outflow channel 16 being flush with or recessed in the bottom surface of the support 15 before deformation, the bottom surface of the outflow channel 16 protruding above the bottom surface of the support 15 after deformation. Optionally, the support portion 15 is of a telescopic or foldable or breakable structure to achieve a deformable effect. In the embodiment, the supporting portion 15 is annular, and the outer circumference of the supporting portion 15 is provided with a groove 151 which is easy to break. Before the specimen is broken off, the bottom end of the outflow channel 16 is recessed in the bottom end of the supporting portion 15, so as to prevent the specimen from losing due to the fact that a user mistakenly opens the second cover body 17; when the liquid containing the specimen is to be taken out of the collecting device, the supporting portion 15 is broken along the groove 151, and the bottom end of the outflow channel 16 is exposed from the supporting portion 15 to facilitate the user to screw-cap the second cap body 17.
The use of the present invention is explained below by taking the collection of stool samples as an example. When collecting the specimen, the collecting container 1 is firstly held tightly and the collector 2 is screwed out. If solid excrement is encountered, the sampling spoon 22 is adopted to collect excrement samples, and excrement samples in the middle-section excrement need to be collected, so that human intestinal epithelial cast-off cells adhered to the surface of the excrement are prevented from being mixed, and subsequent nucleic acid detection and analysis are prevented from being influenced; the amount of the collected liquid is two thirds to one spoon; if liquid excrement is encountered, the excrement sample is collected by the dropper 21, specifically, the dropper cap 211 is squeezed, the collector 2 is inclined, the inclined plane tip 214 of the dropper 21 is attached to the surface of the liquid excrement, and the dropper cap 211 is slowly released until the collected liquid excrement reaches the indicating line 215. After the collection is completed, the sampling spoon 22 and the dropper 21 are transferred to the sample chamber 13 of the collection container 1, the first cover 23 is screwed, and the sample chamber 13 is closed by the first sealing member 231. The clamping and fixing piece 24 is taken down, the dropper 21 is screwed downwards by taking the dropper cap 211 as a supporting point, and the specimen cavity 13 is further closed under the action of the second sealing piece 232; after the dropper 21 is screwed, the inclined tip 214 of the dropper 21 can puncture the interlayer 12, so that the liquid storage cavity 11 is the same as the sample cavity 13, and the protective liquid 111 enters the sample cavity 13 under the action of gravity to immerse the fecal sample. Shaking the collection device left and right to mix the fecal sample with the protective solution 111.
Before detecting, place abundant mixing on shaking the blending machine with collection container 1 earlier, then extrude the recess 151 of easy rupture, rupture supporting part 15 takes off second lid 17, places collection device perpendicularly on collecting the household utensils, and excrement and urine and the mixed solution of protection liquid pass through filter 161 under the action of gravity, filter impurity such as food waste and dietary fiber, can follow the fungus liquid of outflow channel 16 collection high concentration, the development of the follow-up clinical detection project of being convenient for.
While the preferred embodiments of the present invention have been described in detail, it will be understood by those skilled in the art that the invention is not limited to the details of the embodiments shown, but is capable of various modifications and substitutions without departing from the spirit of the invention.

Claims (9)

1. A specimen collection device, comprising:
the collecting container (1) is provided with an opening, a liquid storage cavity (11) and a specimen cavity (13) are arranged in the collecting container (1), the opening is communicated with the specimen cavity (13), the liquid storage cavity (11) and the specimen cavity (13) are separated by a spacing structure, and the spacing structure comprises an interlayer (12) which can be broken under the action of external force;
collector (2), collector (2) are including the first lid (23) of sampling spare and detachable, first lid (23) are used for the closing cap the opening, the sampling spare is including first sampling spare, the first end of first sampling spare is fixed on first lid (23), the second end of first sampling spare can stretch into in sample chamber (13) and make interlayer (12) rupture.
2. The specimen collection device according to claim 1, characterized in that: the liquid storage cavity (11) surrounds the side surface and the bottom surface of the specimen cavity (13), the spacing structure further comprises a spacing wall, the side surface of the specimen cavity (13) passes through the spacing wall and the liquid storage cavity (11) are spaced, and the bottom surface of the specimen cavity (13) passes through the spacing wall (12) and the liquid storage cavity (11) are spaced.
3. The specimen collection device according to claim 2, characterized in that: an openable and closable outflow channel (16) is arranged on the outer side of the liquid storage cavity (11).
4. The specimen collection device according to claim 3, characterized in that: the outflow channel (16) is located on the bottom surface of the liquid storage cavity (11), a deformable supporting part (15) is arranged at the bottom of the collector (2), the bottom surface of the outflow channel (16) is flush with or recessed in the bottom surface of the supporting part (15) before deformation, and the bottom surface of the outflow channel (16) protrudes out of the bottom surface of the supporting part (15) after deformation.
5. The specimen collection device according to claim 3, characterized in that: the outflow channel (16) comprises an outflow opening, on which a filter (161) is arranged, and a second cover (17) for closing the outflow opening.
6. The specimen collection device according to claim 1, characterized in that: the side wall of the first end of the first sampling piece is connected with a detachable clamping piece (24), the first cover body (23) is provided with a fixing through hole, the first sampling piece penetrates through the fixing through hole, the first sampling piece is in sealing fit with the fixing through hole, and the clamping piece (24) abuts against the end face, far away from the collecting container (1), of the first cover body (23).
7. The specimen collection device according to claim 6, characterized in that: the side wall of the first sampling piece is provided with an external thread (213), the clamping piece (24) is provided with an internal thread, and the first sampling piece is in threaded connection with the clamping piece (24).
8. The specimen collection device according to any one of claims 1 to 7, wherein: the sampling piece further comprises a second sampling piece, the first sampling piece is a dropper (21), the second end of the dropper (21) is a tip end, and the second sampling piece is a sampling spoon (22).
9. The specimen collection device according to any one of claims 1 to 7, wherein: the first cover body (23) is in threaded connection with the collection container (1), and a first sealing piece (231) is arranged between the first cover body (23) and the collection container (1).
CN202021255351.4U 2020-06-30 2020-06-30 Sample collection device Active CN212894721U (en)

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CN202021255351.4U CN212894721U (en) 2020-06-30 2020-06-30 Sample collection device

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Application Number Priority Date Filing Date Title
CN202021255351.4U CN212894721U (en) 2020-06-30 2020-06-30 Sample collection device

Publications (1)

Publication Number Publication Date
CN212894721U true CN212894721U (en) 2021-04-06

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Application Number Title Priority Date Filing Date
CN202021255351.4U Active CN212894721U (en) 2020-06-30 2020-06-30 Sample collection device

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