CN212845412U - Two-step multi-connection immunochromatography detection buckle - Google Patents
Two-step multi-connection immunochromatography detection buckle Download PDFInfo
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- CN212845412U CN212845412U CN202022030596.3U CN202022030596U CN212845412U CN 212845412 U CN212845412 U CN 212845412U CN 202022030596 U CN202022030596 U CN 202022030596U CN 212845412 U CN212845412 U CN 212845412U
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- buckle
- test paper
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- paper strip
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
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- Urology & Nephrology (AREA)
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- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Abstract
The utility model discloses a two-step process allies oneself with immunochromatography detection buckle more, first knot body, second including mutual lock joint detain the body and test paper strip, first knot body is used for fixed test paper strip more than two, test paper strip length direction's one end is equipped with the sample pad and extends first knot body setting, the second is detained the body and is used for covering the sample pad. The utility model discloses a detection buckle makes the immunochromatography test paper strip of two-step method can realize linking more the detection through setting up a plurality of test paper strips, and detains the setting of body through first knot body and second and make the test paper strip can be exposed when using, contacts and then realizes linking more the detection with the solution in the golden cup, and the test paper strip is detained the body by the second when not using and is covered the protection, has avoided the damage and the pollution of test paper strip.
Description
Technical Field
The utility model relates to a food detection technology field, more specifically relates to a two-step process allies oneself with immunochromatography and detects buckle more.
Background
The immunochromatography technology is a rapid clinical detection technology recently popular in medical circles at home and abroad, and is characterized by single-person determination, simplicity and rapidness.
In the rapid detection of food safety, simultaneous detection of a plurality of targets is becoming a great trend in order to improve detection efficiency. A plurality of test paper strips are connected in parallel for use, and the simultaneous detection of a plurality of different items can be realized. However, the conventional method is generally based on a one-step method, i.e., a gold pad method, and cannot be compatible with a two-step method using a gold cup, so that the detection workload is large, and the detection efficiency is low.
SUMMERY OF THE UTILITY MODEL
In order to solve the not enough of prior art, the utility model provides a two-step method allies oneself with immunochromatography and detects the buckle for the immunochromatography test strip of two-step method can realize alliing oneself with the detection more, and the design of buckle makes the test strip receive the protection simultaneously, has avoided external environment to its influence.
The utility model discloses the technological effect that will reach is realized through following scheme: the utility model provides a two-step process allies oneself with immunochromatography detection buckle more, includes the first knot body, the second of mutual lock joint and detains body and test paper strip, first knot body is used for fixed more than two test paper strips, test paper strip length direction's one end is equipped with the sample pad and extends first knot body setting, the second is detained the body and is used for covering the sample pad.
Preferably, first knot body includes last piece casing and lower piece casing of mutual lock joint, one side that the piece casing was gone up to the piece casing is equipped with more than two test paper strip bearing structure down, the test paper strip corresponds the setting on test paper strip bearing structure and fixed through last piece casing and the lower piece casing of lock joint.
Preferably, the lower sheet shell is extended with a gasket corresponding to the sample pad.
Preferably, the pad extends beyond the end shorter than the end of the sample pad.
Preferably, the second buckle body is in a groove cover shape with one open end, and the open end of the second buckle body is arranged towards the sample pad and is buckled with the first buckle body.
Preferably, the upper shell is further provided with a viewing window, and the second buckle body is further provided with a notch corresponding to the viewing window, so as to avoid the viewing window.
Preferably, an area for setting the identification code is reserved on the outer surface of the upper piece shell.
Preferably, the test strip support structure is a frame-shaped structure integrally formed with the lower piece shell, and the interior of the frame-shaped structure is hollow.
Preferably, the frame-shaped structure is internally provided with protrusions which extend inwards in parallel.
The utility model has the advantages of it is following:
the utility model discloses a detection buckle makes the immunochromatography test paper strip of two-step method can realize linking more the detection through setting up a plurality of test paper strips, and detains the setting of body through first knot body and second and make the test paper strip can be exposed when using, contacts and then realizes linking more the detection with the solution in the golden cup, and the test paper strip is detained the body by the second when not using and is covered the protection, has avoided the damage and the pollution of test paper strip.
Drawings
FIG. 1 is a schematic view of a three-dimensional structure of a two-step multiple immunochromatography detection buckle assembly of the present invention;
fig. 2 is a schematic view of the three-dimensional structure of the split state of the first buckle body and the second buckle body in the two-step multi-linked immunochromatography detection buckle of the present invention;
fig. 3 is a schematic view of the decomposition structure of the two-step multi-linked immunochromatography detection buckle of the present invention.
Detailed Description
The invention is described in detail below with reference to the drawings, wherein examples of the embodiments are shown in the drawings, wherein like or similar reference numerals refer to like or similar elements or elements having like or similar functions throughout. The embodiments described below with reference to the drawings are exemplary and intended to be used for explaining the present invention, and should not be construed as limiting the present invention.
In the description of the present invention, it is to be understood that the terms "length," "width," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," and the like are used in the orientation or positional relationship indicated in the drawings for convenience in describing the present invention and for simplicity in description, and are not intended to indicate or imply that the device or element so referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus should not be construed as limiting the present invention.
Furthermore, the terms "first", "second", "third" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first," "second," or "third" may explicitly or implicitly include one or more of that feature. In the description of the present invention, "a plurality" means two or more unless specifically limited otherwise.
In the present invention, unless otherwise expressly stated or limited, the terms "mounted," "connected," "secured," and "disposed" are to be construed broadly, e.g., as meaning either a fixed connection, a removable connection, or an integral part; can be mechanically or electrically connected; they may be directly connected or indirectly connected through intervening media, or may be connected through the interconnection of two elements or through the interaction of two elements. The specific meaning of the above terms in the present invention can be understood according to specific situations by those skilled in the art.
With reference to fig. 1 to fig. 3, an embodiment of the present invention provides a two-step multi-link immunochromatography detection buckle, including a first buckle body 100, a second buckle body 200 and a test strip 300 that are fastened to each other, the first buckle body 100 is used for fixing more than two test strips 300 (shown in the figure as 4), one end of the test strip 300 in the length direction is provided with a sample pad 310 and extends out of the first buckle body 100, and the sample pad 310 is used for extending into a gold cup to contact with a solution. The second button 200 is used to cover the sample pad 310, thereby protecting the sample pad 310. The two-step method is more extensive in food safety short-term test field's application and one-step method, the utility model discloses a detection buckle makes the immunochromatography test paper strip of two-step method can realize linking more to detect through setting up a plurality of test paper strips 300, and makes test paper strip 300 can be exposed when using through the setting of first knot body 100 and second knot body 200, contacts and then realizes linking more to detect with the solution in the golden cup, and test paper strip 300 is covered the protection by second knot body 200 when not using, has avoided the damage and the pollution of test paper strip 300.
Specifically, the first buckle body 100 includes an upper piece housing 110 and a lower piece housing 120 that are fastened to each other, one side of the lower piece housing 120 facing the upper piece housing 110 is provided with two or more test strip support structures 130, the test strip 300 is correspondingly disposed on the test strip support structures 130 and fixed by the fastened upper piece housing 110 and lower piece housing 120, and the test strip support structures 130 are used for protecting the test strip 300 from being collided or pressed, bent and deformed in the using process. Preferably, the number of the test strips 300 is the same as the number of the test strip support structures 130, i.e. one test strip support structure 130 corresponds to each test strip 300. Preferably, the lower case 120 further extends with a gasket 140 corresponding to the sample pad 310 for preventing the sample pad 310 from being collided or pressed to be deformed. Further, the end of the pad 140 extending out may be slightly shorter than the end of the sample pad 310, which may ensure that the test strip 300 can fully contact the solution in the gold cup during the process of extending into the gold cup.
The test strip support structure 130 may be a frame-shaped structure integrally formed with the lower shell 120, and the interior of the frame-shaped structure is hollow, so that the test strip 300 is supported, and the test strip 300 can absorb solution conveniently. The frame structure may also have protrusions 140 extending inward in parallel to further enhance the support of the test strip 300.
Furthermore, an area a for setting an identification code is reserved on the outer surface of the upper shell 110 and used for printing or printing the identification code on the upper shell 110, and each detection buckle corresponds to one identification code, so that information tracking and marking are facilitated. The identification code can be a two-dimensional code or a bar code and has the function of unique identification.
The utility model discloses in, the inspection window 150 has still been seted up to last piece casing 110 for observe T, C lines or further be used for observing the project that the test paper strip corresponds, the position setting of inspection window 150 corresponding test paper strip 300. Further, the observation window 150 is further provided with a transparent protective film for preventing the observed portion from being affected by the environment and other factors.
The utility model discloses in, specifically, the second detains body 200 is one end opening 210's cell type lid form, the opening 210 one end of the second detains body 200 sets up towards sample pad 310 and realizes the guard action to sample pad 310 with first knot body 100 lock joint. The second buckle body 200 is further provided with a notch 220 at a position corresponding to the viewing window 150 for avoiding the viewing window 150, so that the viewing window 150 can be observed when the first buckle body 100 and the second buckle body 200 are buckled.
Go up the chip casing 110 and the lock joint structure of lower chip casing 120 and the lock joint structure of first knot body 100 and second knot body 200 can adopt the conventional design among the prior art, the utility model discloses do not do specifically and prescribe a limit to and give unnecessary detail.
When detection is needed, a gold cup can be embedded in the second buckle body 200, so that detection is more integrated.
The utility model discloses a during the assembly of detection buckle to the quadruple is as an example, keeps flat the test paper strip 300 of four different test paper strips on the test paper strip bearing structure 130 that corresponds earlier, will carve the last casing 110 of two-dimensional code and assemble into first knot body 100 with lower casing 120 lock joint again, assembles into the detection buckle with second knot body 200 and first knot body 100 lock joint again. And finally, the assembled detection buckle and the matched quadruple reaction cup can be sealed, dried and stored, and preferably, an aluminum foil bag is adopted for sealing and storing.
The utility model discloses use and detect remaining tetrad immunochromatography detection buckle of 16 kinds of medicines in milk as the example, this detection buckle can detect monensin in milk simultaneously, bacitracin, spiramycin, florfenicol, trimethoprim, colistin, albendazole, sulfonamides, neomycin, kanamycin, spectinomycin, gentamycin, erythromycin, lincomycin, tylosin/tilmicosin, fluoroquinolone class medicine is remained. The detection buckle comprises four detection test strips, each test strip is provided with 4T lines, and four different medicines can be detected. When the detection is carried out, the quadruple reaction cup printed with the item numbers 1-4 is taken out, and 200 mu L of milk samples are sequentially added into the quadruple reaction cup. And then placing the quadruple reaction cup in an incubator at 40 ℃, reacting for 3 minutes, taking out the quadruple immunochromatography detection buckle printed with item numbers 1-4, taking down the second buckle body 200, and correspondingly inserting the second buckle body 200 into the quadruple reaction cup. After reacting for 7 minutes again, the second button 200 is taken out of the quadruple reaction cup, the test strip 300 at the lower end of the test strip is scraped, and the result is interpreted.
The interpretation of the results can be divided into macroscopic interpretation and instrumental interpretation. The color depth of the C line and the T line can be observed by naked eyes through a window, and the result can be interpreted. The quadruple immunochromatography detection buckle can also be arranged in a matched reading instrument, the reading instrument can automatically identify buckle related information such as a cargo number, a batch, detection items and the like according to the two-dimensional code on the buckle, and the quadruple immunochromatography buckle is scanned to display an interpretation result.
Finally, it should be noted that the above embodiments are only used for illustrating the technical solutions of the embodiments of the present invention and not for limiting the same, and although the embodiments of the present invention are described in detail with reference to the preferred embodiments, it should be understood by those skilled in the art that modifications or equivalent substitutions can be made on the technical solutions of the embodiments of the present invention, and these modifications or equivalent substitutions cannot make the modified technical solutions depart from the scope of the technical solutions of the embodiments of the present invention.
Claims (9)
1. The utility model provides a two-step process allies oneself with immunochromatography detection buckle more, its characterized in that, detains body and test paper strip including the first knot body of mutual lock joint, second, first knot body is used for fixed more than two test paper strips, test paper strip length direction's one end is equipped with the sample pad and extends first knot body setting, the second is detained the body and is used for covering the sample pad.
2. The two-step multi-connected immunochromatographic assay buckle of claim 1, wherein the first buckle body comprises an upper shell and a lower shell which are fastened to each other, one side of the lower shell facing the upper shell is provided with more than two test strip support structures, and the test strips are correspondingly arranged on the test strip support structures and fixed through the upper shell and the lower shell which are fastened to each other.
3. The two-step multiple immunochromatographic assay clasp of claim 2, wherein the lower shell further has a gasket extending from the sample pad.
4. The two-step multiple immunochromatographic assay cartridge of claim 3, wherein the pad extends beyond the end of the pad shorter than the end of the sample pad.
5. The two-step multiple immunochromatographic assay fastener of claim 2, wherein the second fastener is in the form of a slot-shaped cap with an open end, and the open end of the second fastener is disposed toward the sample pad and fastened to the first fastener.
6. The two-step multi-connected immunochromatographic detection buckle of claim 5, wherein the upper shell is further provided with a viewing window, and the second buckle body is further provided with a notch corresponding to the viewing window for avoiding the viewing window.
7. The two-step multi-connected immunochromatography detection buckle according to claim 2, wherein an area for setting an identification code is reserved on the outer surface of the upper shell.
8. The two-step multi-connected immunochromatographic assay buckle of claim 2, wherein the test strip support structure is a frame-shaped structure integrally formed with the lower shell, and the interior of the test strip support structure is hollow.
9. The two-step multiple immunochromatographic assay clasp of claim 8, wherein the frame structure further has protrusions extending inwards in parallel.
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202022030596.3U CN212845412U (en) | 2020-09-16 | 2020-09-16 | Two-step multi-connection immunochromatography detection buckle |
| RU2021120482U RU208858U1 (en) | 2020-09-16 | 2021-02-08 | Test cassette with multiple compounds for two-stage immunochromatographic diagnostics |
| PCT/CN2021/076005 WO2022057200A1 (en) | 2020-09-16 | 2021-02-08 | Two-step multiplex immunochromatographic detection fastener |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202022030596.3U CN212845412U (en) | 2020-09-16 | 2020-09-16 | Two-step multi-connection immunochromatography detection buckle |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN212845412U true CN212845412U (en) | 2021-03-30 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202022030596.3U Active CN212845412U (en) | 2020-09-16 | 2020-09-16 | Two-step multi-connection immunochromatography detection buckle |
Country Status (2)
| Country | Link |
|---|---|
| CN (1) | CN212845412U (en) |
| WO (1) | WO2022057200A1 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113189328A (en) * | 2021-05-10 | 2021-07-30 | 齐鲁工业大学 | Multi-channel detection test paper box and application thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1377300A (en) * | 2000-09-19 | 2002-10-30 | 辛特朗生物研究公司 | Multiple analyte assay device with sample integrity monitoring system |
| CN2916633Y (en) * | 2006-03-10 | 2007-06-27 | 天津中新科炬生物制药有限公司 | Detection device |
| CN101308132A (en) * | 2007-05-17 | 2008-11-19 | 上海凯创生物技术有限公司 | Multi-link detection reagent kit |
| CN203929776U (en) * | 2014-05-19 | 2014-11-05 | 杭州赛图生物科技有限公司 | Pawl type illicit drugs inspection card |
| CN204422546U (en) * | 2014-12-29 | 2015-06-24 | 霍普金斯医药研究院（北京）有限责任公司 | Injury of kidney five in one test card |
| CN204758602U (en) * | 2015-06-01 | 2015-11-11 | 广州万孚生物技术股份有限公司 | Detect reagent card is united to multinomial mesh |
| US20190240654A1 (en) * | 2018-02-07 | 2019-08-08 | Spectrum Laboratories, Llc | Method and apparatus for mutli-channel urinalysis test kit with multi-factor control |
| CN207908515U (en) * | 2018-03-07 | 2018-09-25 | 珠海中信大有科技有限公司 | A kind of drugs urine detection agent plate |
| CN209264735U (en) * | 2018-12-12 | 2019-08-16 | 深圳市易瑞生物技术股份有限公司 | A kind of high pass amount detecting device for two-step method immunochromatography |
| CN211453648U (en) * | 2020-06-01 | 2020-09-08 | 北京库尔科技有限公司 | Ten-in-one test card shell |
-
2020
- 2020-09-16 CN CN202022030596.3U patent/CN212845412U/en active Active
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2021
- 2021-02-08 WO PCT/CN2021/076005 patent/WO2022057200A1/en active Application Filing
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113189328A (en) * | 2021-05-10 | 2021-07-30 | 齐鲁工业大学 | Multi-channel detection test paper box and application thereof |
| CN113189328B (en) * | 2021-05-10 | 2023-10-13 | 齐鲁工业大学 | Multi-channel test paper box and application thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2022057200A1 (en) | 2022-03-24 |
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