CN212844899U - Bag type sterilization filter damage detection device - Google Patents

Bag type sterilization filter damage detection device Download PDF

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Publication number
CN212844899U
CN212844899U CN202021275549.9U CN202021275549U CN212844899U CN 212844899 U CN212844899 U CN 212844899U CN 202021275549 U CN202021275549 U CN 202021275549U CN 212844899 U CN212844899 U CN 212844899U
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China
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filter
connecting part
bag
bag type
inlet pipe
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CN202021275549.9U
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Chinese (zh)
Inventor
程雷显
孙静静
周雷鸣
赵巧辉
李桂林
付光宇
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Zhengzhou Immuno Biotech Co Ltd
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Zhengzhou Immuno Biotech Co Ltd
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Abstract

The utility model discloses a bag type degerming filter damage detection device, which comprises a first connecting part, a second connecting part and a third connecting part, wherein the first connecting part is arranged on a liquid inlet pipe at the lower end of the bag type degerming filter and is used for being communicated with an external integrity detector in a sealing way; the second connecting part is arranged on the liquid outlet pipe at the upper end of the bag type sterilizing filter; and the third connecting part is arranged between the first connecting part and the second connecting part, the lower end of the third connecting part is fixedly connected with the first connecting part, and the upper end of the third connecting part is fixedly connected with the second connecting part. The utility model has the advantages of simple structure, simple installation, economy and practicality. The first, second and third connecting parts are arranged on the bag-type sterilizing filter, so that the bag-type sterilizing filter is easily butted with the integrity detector, the sealing performance of the whole detection passage is ensured, and the accuracy and reliability of a detection result are ensured; the quick detection is easily realized, the damaged bag type bacteria removing filter is scrapped in time, the influence on the quality of the filtering effect and the final liquid is avoided, and the possibility of sample pollution when the bag type bacteria removing filter is used is greatly reduced.

Description

Bag type sterilization filter damage detection device
Technical Field
The utility model belongs to the technical field of cell culture medium filter sterilization technique and specifically relates to a damaged detection device of capsule type degerming filter is related to.
Background
At present, a sterilization filter is needed in the cell culture in the fields of biology, chemistry, medicine and the like, and particularly, a bag type sterilization filter and an online bag type sterilization filter are used in the long-term cell culture process of a hollow fiber system. The bag type sterilizing filter adopts a folding type inlet filter membrane, has large filtering surface area, is suitable for filtering solution with larger volume, has the appearance of polypropylene material, does not contain adhesive and other chemical substances, ensures no pollution to samples, has different pore diameters to be selected, can perform high-pressure sterilization, and is widely applied to filtering solvents, cells and liquid medicine in chemical industry, biological medicine, food industry, laboratories and the like.
Although the bag-type sterilization filter is usually damaged before or during the use process within the times of autoclaving, the filter cannot be used at the moment and should be scrapped so as not to influence the filtering effect and the quality of the final liquid; therefore, it is necessary to detect the breakage of the bag sterilizing filter. However, the existing bag type sterilizing filter (as shown in fig. 4) is provided with a lip with a frustum-shaped structure at the port of the liquid inlet pipe and the liquid outlet pipe, so that the existing bag type sterilizing filter is difficult to be communicated with the integrity detector in a sealing way, the integrity detector cannot be used for carrying out breakage detection on the bag type sterilizing filter, and the difficulty of breakage detection of the bag type sterilizing filter is greatly improved.
Disclosure of Invention
The utility model aims to provide a simple structure, the damaged detection device of bag formula degerming filter simple to handle.
In order to achieve the above purpose, the utility model can adopt the following technical proposal:
the bag type degerming filter damage detection device comprises a first connecting part, a second connecting part and a third connecting part, wherein the first connecting part is arranged on a liquid inlet pipe at the lower end of the bag type degerming filter and is used for being communicated with an external integrity detector in a sealing way; the second connecting part is arranged on the liquid outlet pipe at the upper end of the bag type sterilizing filter; and the third connecting part is arranged between the first connecting part and the second connecting part, the lower end of the third connecting part is fixedly connected with the first connecting part, and the upper end of the third connecting part is fixedly connected with the second connecting part.
The first connecting part comprises a connecting chuck, the connecting chuck is provided with a through type air inlet channel which is arranged along the central axis, the upper end of the air inlet channel is a filter connecting hole with a step-shaped structure, and a liquid inlet pipe of the bag type sterilization filter is movably inserted into the filter connecting hole and is communicated with the air inlet channel; and the packaging assembly is arranged between the liquid inlet pipe of the bag type sterilization filter and the filter connecting hole, and plays a role in sealing.
The connecting chuck comprises a connecting flange connected with the third connecting part and a chuck joint fixedly connected with the lower surface of the connecting flange into a whole through a longitudinal connecting section, and the connecting flange, the longitudinal connecting section and the chuck joint are positioned on the same axis.
The packaging assembly comprises an end face sealing ring which is fixed on the bottom surface of the lower step of the filter connecting hole, and the upper surface of the end face sealing ring is attached to the lower port of the liquid inlet pipe of the bag type sterilization filter to form sealing; the outer diameter sealing ring is fixed on the side wall of the lower step of the filter connecting hole, and the inner ring surface of the outer diameter sealing ring is attached to the outer wall of the liquid inlet pipe of the bag type sterilization filter, which is close to the lower port, so as to form sealing; and the annular mounting sleeve is attached and clamped between the upper step of the filter connecting hole and the liquid inlet pipe of the bag type sterilizing filter and is used for fixing the liquid inlet pipe of the bag type sterilizing filter in the filter connecting hole.
The annular mounting sleeve is formed by buckling a pair of semicircular spacer sleeves with the same structure.
The second connecting part is a fixed flange.
The third connecting part is a connecting screw rod; the four connecting screw rods are uniformly distributed at intervals along the circumferential direction of the outer wall of the bag type bacteria removing filter.
The utility model has the advantages of simple structure, simple installation, economy and practicality. The first connecting part, the second connecting part and the third connecting part are arranged on the bag-type sterilizing filter, so that the bag-type sterilizing filter is easily butted with an external integrity detector, the sealing performance of the whole detection passage is ensured, and the accuracy and the reliability of a detection result are ensured; the rapid detection of the bag type bacteria removing filter before and after use is easily realized, so that the damaged bag type bacteria removing filter is scrapped in time, the influence on the quality of the filtering effect and the final liquid is avoided, and the possibility of sample pollution when the bag type bacteria removing filter is used is greatly reduced.
Drawings
Fig. 1 is a schematic structural diagram of the present invention.
Fig. 2 is a view in the direction a of fig. 1.
Fig. 3 is an enlarged view of a portion I of fig. 1.
FIG. 4 is a schematic structural diagram of a conventional bag-type sterilizing filter.
Detailed Description
The embodiments of the present invention will be described in detail with reference to the accompanying drawings, which are implemented on the premise of the technical solution of the present invention, and the detailed embodiments and the specific operation procedures are given, but the scope of the present invention is not limited to the following embodiments.
As shown in fig. 1-3, the bag type sterilization filter damage detection device of the present invention includes a first connection portion, which is installed on a liquid inlet pipe at the lower end of the bag type sterilization filter 1 and is used for being hermetically communicated with an external integrity detector; the second connecting part is arranged on the liquid outlet pipe at the upper end of the bag-type sterilizing filter 1; and the third connecting part is arranged between the first connecting part and the second connecting part, the lower end of the third connecting part is fixedly connected with the first connecting part, and the upper end of the third connecting part is fixedly connected with the second connecting part.
Specifically, the first connecting portion includes a connecting chuck and a package assembly.
The connecting chuck is composed of a connecting flange 2, a longitudinal connecting section 3 and a chuck joint 4 which are positioned on the same axis, and the chuck joint 4 is fixedly connected with the lower surface of the connecting flange 2 through the longitudinal connecting section 3, so that an integrated structure is formed; the connecting flange 2 is intended to be connected to a third connection, and the chuck adapter 4 is intended to be connected to an external integrity detector. A through type air inlet channel 5 is arranged on the connecting chuck of an integrated structure consisting of the connecting flange 2, the longitudinal connecting section 3 and the chuck joint 4 along the central axis, the upper end of the air inlet channel 5 is a filter connecting hole 6 with a step-shaped structure, and the liquid inlet pipe of the bag-type sterilization filter 1 is movably inserted into the filter connecting hole 6 and is communicated with the air inlet channel 5.
The packaging assembly comprises an end face sealing ring 7 and an outer diameter sealing ring 8 which are arranged between a liquid inlet pipe of the bag type degerming filter 1 and the filter connecting hole 6 and play a role in sealing, and an annular mounting sleeve 9 which plays a role in mounting and fixing.
The end face sealing ring 7 is fixed on the bottom surface of the lower step of the filter connecting hole 6, and the upper surface of the end face sealing ring is attached to the lower port of the liquid inlet pipe of the bag-type sterilizing filter 1 inserted into the filter connecting hole 6; because the lower port of the liquid inlet pipe of the bag-type sterilizing filter 1 is provided with a lip with a frustum structure, an outer diameter sealing ring 8 is arranged for ensuring the sealing of the position, and the outer diameter sealing ring 8 is fixed on the side wall of the lower step of the filter connecting hole 6. In actual installation, annular grooves 10 for clamping the end face sealing ring 7 and the outer diameter sealing ring 8 can be respectively formed on the bottom surface and the side wall of the lower step of the filter connecting hole 6, the end face sealing ring 7 and the outer diameter sealing ring 8 are respectively fixed in the two annular grooves 10, the upper surface of the end face sealing ring 7 extends out of the annular grooves 10 and is attached to the lower end face of the liquid inlet pipe of the bag-type sterilization filter 1, and therefore first-stage sealing is formed; the inner ring surface of the outer diameter sealing ring 8 is positioned outside the ring groove 10 and is attached to the outer wall of the lip of the liquid inlet pipe of the bag type bacteria removing filter 1 close to the lower port, so that second-stage sealing is formed.
The annular mounting sleeve 9 is fitted and clamped between the upper step of the filter connecting hole 6 and the liquid inlet pipe of the bag-type sterilizing filter 1 and is used for fixing the liquid inlet pipe and the bag-type sterilizing filter 1 in the filter connecting hole 6; in addition, for convenient installation, the annular installation sleeve 9 can be formed by buckling a pair of semicircular spacer sleeves with the same structure.
The second connecting part is a fixing flange 11, and the fixing flange 11 is matched with the connecting flange 2 of the connecting chuck and sleeved on a liquid outlet pipe at the upper end of the bag-type sterilizing filter 1.
The third connecting portion are connecting screw 12, and connecting screw 12 can be evenly arranged four along outer wall circumference interval of bag formula bacteria elimination filter 1, and four connecting screw 12's upper end is connected with mounting flange 11, and its lower extreme is connected with connection chuck's flange 2 to fixed bag formula bacteria elimination filter 1 under mounting flange 11 and connection flange 2's common clamping effect.
When the device is installed, firstly, the exhaust ports 13 on two sides of the bag-type sterilizing filter 1 are opened, purified water is injected into the bag-type sterilizing filter 1 from the liquid inlet pipe, and filter membranes of the bag-type sterilizing filter 1 are fully wetted; then installing and fixing an end face sealing ring 7 and an outer diameter sealing ring 8; then the lower ends of the four connecting screws 12 are screwed on the connecting flange 2 of the connecting chuck; then an annular mounting sleeve 9 formed by buckling two semicircular spacers is arranged at the position above the lip of the liquid inlet pipe of the bag-type sterilizing filter 1 in a surrounding manner and is inserted into a filter connecting hole 6 on a connecting chuck together with the bag-type sterilizing filter 1; then the fixing flange 11 is sleeved on the liquid outlet pipe of the bag-type sterilizing filter 1 and is connected with the upper ends of the four connecting screw rods 12, thereby completing the installation of the bag-type sterilizing filter 1.
After all the filter cartridges are installed, the chuck joint 4 connected with the lower end of the chuck can be connected with an external integrity detector in a sealing mode through a standard throat hoop and a gasket, the tightness of the bag-type sterilizing filter 1 can be measured according to a set parameter program, the bag-type sterilizing filter 1 which is measured to be qualified can be used again, and the bag-type sterilizing filter 1 which is not measured to be qualified is discarded.

Claims (8)

1. The utility model provides a damaged detection device of capsule type degerming filter which characterized in that: comprises that
The first connecting part is arranged on a liquid inlet pipe at the lower end of the bag type sterilization filter and is used for being communicated with an external integrity detector in a sealing way;
the second connecting part is arranged on the liquid outlet pipe at the upper end of the bag type sterilizing filter; and
and the third connecting part is arranged between the first connecting part and the second connecting part, the lower end of the third connecting part is fixedly connected with the first connecting part, and the upper end of the third connecting part is fixedly connected with the second connecting part.
2. The bag sterilizing filter breakage detecting apparatus according to claim 1, characterized in that: the first connecting part comprises
The connecting chuck is provided with a through type air inlet channel which is arranged along the central axis, the upper end of the air inlet channel is a filter connecting hole with a step-shaped structure, and a liquid inlet pipe of the bag type sterilization filter is movably inserted into the filter connecting hole and is communicated with the air inlet channel; and
the encapsulation subassembly, set up in the feed liquor pipe of bag formula degerming filter with between the filter connecting hole, play sealed effect.
3. The bag sterilizing filter breakage detecting apparatus according to claim 2, characterized in that: the connecting chuck comprises a connecting flange connected with the third connecting part and a chuck joint fixedly connected with the lower surface of the connecting flange into a whole through a longitudinal connecting section, and the connecting flange, the longitudinal connecting section and the chuck joint are positioned on the same axis.
4. The bag sterilizing filter breakage detecting apparatus according to claim 2, characterized in that: the package assembly includes
The end face sealing ring is fixed on the bottom surface of the lower step of the filter connecting hole, and the upper surface of the end face sealing ring is attached to the lower port of the liquid inlet pipe of the bag type sterilization filter to form sealing;
the outer diameter sealing ring is fixed on the side wall of the lower step of the filter connecting hole, and the inner ring surface of the outer diameter sealing ring is attached to the outer wall of the liquid inlet pipe of the bag type sterilization filter, which is close to the lower port, so as to form sealing; and
and the annular mounting sleeve is attached and clamped between the upper step of the filter connecting hole and the liquid inlet pipe of the bag type sterilizing filter and is used for fixing the liquid inlet pipe of the bag type sterilizing filter in the filter connecting hole.
5. The sterilization filter breakage detection apparatus of the capsule type according to claim 4, characterized in that: the annular mounting sleeve is formed by buckling a pair of semicircular spacer sleeves with the same structure.
6. The bag sterilizing filter breakage detecting apparatus according to claim 1, characterized in that: the second connecting part is a fixed flange.
7. The bag sterilizing filter breakage detecting apparatus according to claim 1, characterized in that: the third connecting part is a connecting screw rod.
8. The sterilization filter breakage detection apparatus of the capsule type according to claim 7, characterized in that: the four connecting screw rods are uniformly distributed at intervals along the circumferential direction of the outer wall of the bag type bacteria removing filter.
CN202021275549.9U 2020-07-03 2020-07-03 Bag type sterilization filter damage detection device Active CN212844899U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202021275549.9U CN212844899U (en) 2020-07-03 2020-07-03 Bag type sterilization filter damage detection device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202021275549.9U CN212844899U (en) 2020-07-03 2020-07-03 Bag type sterilization filter damage detection device

Publications (1)

Publication Number Publication Date
CN212844899U true CN212844899U (en) 2021-03-30

Family

ID=75181048

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202021275549.9U Active CN212844899U (en) 2020-07-03 2020-07-03 Bag type sterilization filter damage detection device

Country Status (1)

Country Link
CN (1) CN212844899U (en)

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