CN212586400U

CN212586400U - Suction nozzle replacing structure on full-automatic immunoblotting instrument

Info

Publication number: CN212586400U
Application number: CN202021294444.8U
Authority: CN
Inventors: 李东琦
Original assignee: Eurasia Pioneer Biotechnology Investment Beijing Co ltd
Current assignee: Eurasia Pioneer Biotechnology Investment Beijing Co ltd
Priority date: 2020-07-04
Filing date: 2020-07-04
Publication date: 2021-02-23
Anticipated expiration: 2030-07-04

Abstract

The utility model relates to a structure is changed to suction nozzle on full-automatic immunoblotting appearance, which comprises a frame, be provided with the sample box in the frame, it is provided with the deep bid to rotate in the frame, the sample box sets up on the deep bid, one side that the frame is located the deep bid is equipped with the suction nozzle rack, be provided with the suction nozzle on the suction nozzle rack, be provided with horizontal reciprocating motion's sample filling mechanism between deep bid, suction nozzle rack in the frame, the sample filling mechanism includes the lift drive assembly that second syringe, drive second syringe go up and down, after the second syringe descends a take the altitude, the cooperation of pegging graft of suction nozzle on one end and the suction nozzle rack. One end of the second injector is driven by the lifting driving component to be in plug-in fit with the suction nozzle on the suction nozzle placing frame, the unused suction nozzle is installed on the second injector, the new suction nozzle is replaced on the second injector, the new unused suction nozzle is adopted to suck different samples, and cross contamination is prevented.

Description

Suction nozzle replacing structure on full-automatic immunoblotting instrument

Technical Field

The utility model relates to a full-automatic immunoblotting appearance especially relates to a structure is changed to suction nozzle on full-automatic immunoblotting appearance.

Background

The immunoblotting method is widely used for autoantibody detection, allergen detection and protein detection, and mainly carries out qualitative and semi-quantitative analysis on a detected object.

In order to solve the above problems, in a chinese patent document with an issued publication number of CN207992247U, the full-automatic immunoblotting instrument comprises an instrument body, wherein a moving track is arranged on the instrument body, a membrane strip groove and a sample rack, the membrane strip groove is used for accommodating a blotting membrane, a plurality of sample test tube grooves are formed in the sample rack, the sample test tube grooves are used for placing sample test tubes, a second moving arm is arranged on the moving track, a plurality of waste suction channels and a plurality of reagent adding channels are arranged on the second moving arm, a sample adding needle head is arranged on the first moving arm and is used for extracting sample liquid in the sample test tubes and moving along a first direction to drip the sample liquid onto the blotting membrane, an operator edits a program of an experimental project on a control device in advance, scans bar codes on the sample test tubes before an experiment begins, sequentially places the sample test tubes on the sample rack and places the blotting strips in the membrane strip groove; after starting the instrument, automatically completing the whole experimental process; and finally, shooting by using the CCD, interpreting an experimental result with the assistance of a computer, and generating and printing a result report.

The above prior art solutions have the following drawbacks: in the process of sucking the sample, in order to avoid cross contamination between different samples, after the sample is sucked and added into the reaction tank, the needle head needs to be replaced in time so as to suck different samples next time.

SUMMERY OF THE UTILITY MODEL

The utility model aims at providing a structure is changed to suction nozzle on the full-automatic immunoblotting appearance, through the quick replacement that sample filling mechanism and lift drive assembly realized the suction nozzle.

The above utility model discloses an above-mentioned utility model purpose can realize through following technical scheme:

the utility model provides a structure is changed to suction nozzle on full-automatic immunoblotting appearance, includes the frame, be provided with the sample box in the frame, it is provided with the deep bid to rotate in the frame, the sample box sets up on the deep bid, one side that the frame is located the deep bid is equipped with the suction nozzle rack, be provided with the suction nozzle on the suction nozzle rack, be provided with horizontal reciprocating motion's sample filling mechanism between deep bid, suction nozzle rack in the frame, the sample filling mechanism includes the lift drive assembly that second syringe, drive second syringe go up and down, after the second syringe descends the take the altitude, one end is pegged graft the cooperation with the suction nozzle on the suction nozzle rack.

Through adopting above-mentioned technical scheme, take off the used suction nozzle on the second syringe, sample filling mechanism lateral shifting is to suction nozzle rack top department after that, descend the take the altitude through lift drive assembly drive second syringe, the one end of second syringe and the cooperation of pegging graft of the suction nozzle on the suction nozzle rack, install unused suction nozzle on the second syringe, the completion is changed new suction nozzle to the second syringe, the suction nozzle on the quick replacement sample filling mechanism, adopt new unused suction nozzle to absorb different samples, the prevention cross contamination.

The utility model discloses further set up to: the second injector comprises an injection cylinder body, the injection cylinder body is provided with an insertion port which is detachably inserted and matched with the suction nozzle, and the insertion port is communicated with the inside of the injection cylinder body.

By adopting the technical scheme, after the insertion port is inserted into the suction nozzle, the suction nozzle is communicated with the interior of the syringe barrel through the insertion port, and the sample liquid in the syringe barrel can be injected out of the suction nozzle through the insertion port and the suction nozzle on the second injector, and the sample liquid can also be sucked into the syringe barrel from the test tube through the suction nozzle and the insertion port.

The utility model discloses further set up to: the second injector further comprises a piston in sliding fit with the injection cylinder body, an injection rod with one end fixedly connected with the piston, and the sample filling mechanism further comprises an injection control assembly for driving the injection rod to move in the injection cylinder body.

Through adopting above-mentioned technical scheme, injection control assembly realizes that the injection pole controls in injection barrel body, and injection pole and piston move up and down in injection barrel body, can go out the liquid injection in the second syringe, or in drawing liquid to the second syringe from the test tube, realize the automatic control to the second syringe.

The utility model discloses further set up to: the lifting driving assembly comprises a moving driving motor, a second ball screw pair and a linkage plate, the second injector is arranged on the linkage plate, and the moving driving motor drives the second ball screw pair to work so as to drive the second injector on the linkage plate to lift.

Through adopting above-mentioned technical scheme, under the drive that removes driving motor, the ball is vice can be stable drives the second syringe and goes up and down, and the elevating movement of second syringe is more stable, high-efficient.

The utility model discloses further set up to: the sample filling mechanism is characterized in that a short-stroke track is arranged on the rack and comprises a second sliding rail extending along the length direction of the rack, and a second sliding groove matched with the second sliding rail in a sliding mode is arranged on the sample filling mechanism.

Through adopting above-mentioned technical scheme, the cooperation that slides of second slide rail and second groove that slides, the second slide rail slides the groove and slides and play the guide effect to sliding on the frame sample filling mechanism with the second, makes sample filling mechanism slide stably, safety on the frame, and sample filling process precision is high.

The utility model discloses further set up to: and a seventh driving mechanism for driving the sample filling mechanism to slide on the second sliding rail is arranged on the rack.

Through adopting above-mentioned technical scheme, seventh actuating mechanism is used for driving sample filling mechanism and slides on the second slide rail, realizes that sample filling mechanism slides automatically, improves the utility model discloses an automatic level.

The utility model discloses further set up to: the seventh driving mechanism comprises a seventh driving motor and a seventh belt pulley assembly, and the seventh driving motor drives the sample filling mechanism to move on the second track through the seventh belt pulley assembly.

Through adopting above-mentioned technical scheme, drive with the belt pulley subassembly, drive sample filling mechanism and remove on the second track, can make sample filling mechanism relatively more stable at the operation in-process, be favorable to sample filling mechanism to carry out sample filling work.

The utility model discloses further set up to: and a sixth driving mechanism for driving the suction nozzle placing frame to move along the width direction of the rack is arranged on the rack.

By adopting the technical scheme, the sixth driving mechanism adjusts the position of the suction nozzle placing frame in the width direction of the rack, so that the suction nozzle placing frame is conveniently moved out of the range of motion of the sample filling mechanism, a worker supplements new unused suction nozzles to the suction nozzle placing frame, and after supplementation is completed, the suction nozzle placing frame is displaced along the width direction of the rack, so that the suction nozzle placing frame is moved into the range of motion of the sample filling mechanism, and a second injector in the sample filling mechanism is convenient to replace new suction nozzles.

The utility model discloses further set up to: the sixth driving mechanism comprises a sixth driving motor and a sixth belt pulley assembly, and the sixth driving motor drives the suction nozzle placing rack to move along the width direction of the rack through the sixth belt pulley assembly.

Through adopting above-mentioned technical scheme, come the transmission with belt pulley assembly, drive the frame on the suction nozzle rack and move for the suction nozzle rack is in the state of stably placing at the in-process that removes, and the phenomenon that the suction nozzle dropped from the suction nozzle rack can not appear.

To sum up, the utility model discloses a beneficial technological effect does:

one end of the second injector is driven to be in plug-in fit with the suction nozzle on the suction nozzle placing frame through the lifting driving assembly, the unused suction nozzle is installed on the second injector, the new suction nozzle is replaced on the second injector, the new unused suction nozzle is adopted to suck different samples, and cross contamination is prevented;

the sample filling mechanism slides stably and safely on the rack, and the precision of the sample filling process is high;

the suction nozzle placing frame is relatively stable in moving, and the suction nozzles on the suction nozzle placing frame are in a stable placing state.

Drawings

FIG. 1 is a first schematic structural diagram of an embodiment, which is used for showing the overall structure of a suction nozzle replacement structure on a full-automatic immunoblotting apparatus;

FIG. 2 is an exploded view of the first embodiment showing the component parts of the first drive mechanism;

FIG. 3 is a second exploded view of the embodiment, showing the installation relationship of the first driving mechanism, the first bearing table and the large plate;

FIG. 4 is an exploded view of the third embodiment illustrating the configuration of the first mounting boss;

FIG. 5 is an enlarged view of part A of FIG. 4, showing the configuration of the sample holder;

FIG. 6 is a second schematic structural view of the embodiment, showing the installation relationship of the nozzle rack;

FIG. 7 is a third schematic structural view of the embodiment, showing the position of the first elongated groove;

FIG. 8 is an enlarged view of the portion B of FIG. 7, showing the components of the sixth driving mechanism;

FIG. 9 is a fourth exploded view of the embodiment for illustrating the placement relationship of the suction nozzle and the suction nozzle placement hole;

FIG. 10 is an enlarged schematic view of portion C of FIG. 9, illustrating the components of the sample filling mechanism;

FIG. 11 is a partial schematic view of the embodiment, illustrating the components of the seventh drive mechanism;

FIG. 12 is a schematic view showing the structure of a specimen filling mechanism in the embodiment;

fig. 13 is an exploded view of the second syringe in the example.

In the figure, 1, a frame; 1.1, a first side plate; 1.2, a bottom plate; 1.3, a first bearing platform; 1.4, a second bearing platform; 2.1, a large disc; 2.2, a first through hole; 2.3, a first mounting shaft sleeve; 2.4, a first bearing; 3. a first drive mechanism; 3.1, a first driving motor; 3.2, a first pulley assembly; 3.3, a driving shaft; 3.4, a first base sleeve disc; 3.5, a first driving wheel; 3.6, a first driven wheel; 3.7, a first belt; 8. a sample mounting rack; 8.1, installing a cavity; 8.2, a sample box; 8.3, placing holes; 8.4, a serum sample test tube; 8.5, an elastic clamping piece; 8.6, clamping a groove; 14. a carriage; 14.1, a third side plate; 14.2, a transverse mounting seat; 14.3, a channel; 14.4, a track plate; 14.5, a first slide rail; 14.6, placing a suction nozzle rack; 14.7, a first track slider; 14.8, a first sliding groove; 14.9, a first elongated groove; 14.10, a first extension block; 14.11, a first limiting block; 14.12, a first bolt; 15. a sixth drive mechanism; 15.1, a sixth driving motor; 15.2, a sixth pulley assembly; 15.3, a sixth driving wheel; 15.4, a sixth driven wheel; 15.5, a sixth belt; 15.6, suction nozzle placing holes; 15.7, a suction nozzle; 15.8, short stroke track; 15.9, a second slide rail; 16. a sample filling mechanism; 16.1, connecting a backing plate; 16.2, a second track slider; 16.3, a second sliding groove; 16.4, a second elongated groove; 16.5, a second extension block; 16.6, a second bolt; 16.7, a second limiting block; 16.8, a seventh drive mechanism; 16.9, a seventh driving motor; 16.10, a seventh pulley assembly; 16.11, a seventh driving wheel; 16.12, a seventh driven wheel; 16.13, a seventh belt; 16.14, a work box; 16.15, a second syringe; 16.16, an injection control assembly; 16.17, a lifting driving component; 16.18, moving the driving motor; 16.19, a second ball screw pair; 16.20, a linkage plate; 16.21, a fifth guide rod; 16.22, embedding holes; 16.23, a guide shaft sleeve; 16.24, a fifth guide hole; 16.25, controlling the motor; 16.26, a control screw rod; 16.28, round holes; 16.29, telescopic guide rods; 16.30, ball nut; 16.31, a driving block; 16.32, a sixth guide hole; 16.33, syringe barrel; 16.34, a piston; 16.35, an injection rod; 16.36, moving the hole; 16.37, connecting hole.

Detailed Description

The present invention will be described in further detail with reference to the accompanying drawings.

The utility model provides a suction nozzle replacement structure on full-automatic immunoblotting appearance, as shown in fig. 1, including frame 1, frame 1 includes bottom plate 1.2, first curb plate 1.1 vertical fixation is in the surface of bottom plate 1.2, one side integrated into one piece of first curb plate 1.1 has first plummer 1.3 and second plummer 1.4, first plummer 1.3, second plummer 1.4 and bottom plate 1.2 parallel, and first plummer 1.3 set up the height and be less than the height that sets up of second plummer 1.4.

As shown in fig. 2 and fig. 3, a large disc 2.1 is rotatably disposed on the first bearing platform 1.3, the large disc 2.1 is disc-shaped and parallel to the first bearing platform 1.3, a first driving mechanism 3 for driving the large disc 2.1 to rotate on the surface of the first bearing platform 1.3 is disposed on the bottom plate 1.2, a first through hole 2.2 penetrating through the bottom surface of the first bearing platform 1.3 is disposed on the surface of the first bearing platform 1.3, a first mounting shaft sleeve 2.3 coaxial with the first through hole 2.2 is fixedly disposed on the surface of the first bearing platform 1.3, and a first bearing 2.4 coaxial with the first through hole 2.2 is fixedly disposed in the first mounting shaft sleeve 2.3.

As shown in fig. 2 and fig. 3, the first driving mechanism 3 includes a first pulley assembly 3.2, a first driving motor 3.1, and a driving shaft 3.3, one end of the driving shaft 3.3 passes through the first through hole 2.2 and the first bearing 2.4, and is fixedly sleeved with the inner ring surface of the first bearing 2.4, one end of the driving shaft 3.3 passing through the first through hole 2.2 is fixedly provided with a first base sleeve 3.4, the first base sleeve 3.4 is fixedly connected with the bottom surface of the large disc 2.1, the first pulley assembly 3.2 includes a first driving wheel 3.5, a first driven wheel 3.6 and a first belt 3.7, the first driven wheel 3.6 is fixedly arranged on the driving shaft 3.3 and is coaxial with the driving shaft 3.3, the first driving wheel 3.5 is fixedly connected with the motor shaft of the first driving motor 3.1 and is coaxially arranged, the first belt 3.7 is annularly sleeved on the first driving wheel 3.5 and the first driven wheel 3.6, the first driving wheel 3.1 is working, the first driving motor 3.5 is self-rotating, the first driven wheel 3.6 is driven to rotate through the first belt 3.7, so that the driving shaft 3.3 is driven to rotate, and the driving shaft 3.3 drives the large disc 2.1 to rotate through the first base sleeve disc 3.4.

As shown in fig. 4 and 5, a plurality of sample mounting racks 8 are arranged at the outer edge of the large plate 2.1, the plurality of sample mounting racks 8 are arranged and distributed along the circumferential direction of the large plate 2.1, a mounting cavity 8.1 is arranged on the sample mounting racks 8, a sample box 8.2 is detachably inserted into the mounting cavity 8.1, the sample box 8.2 is cuboid in shape, placing holes 8.3 are arranged and distributed along the length direction of the sample box 8.2 on the sample box 8.2, serum sample test tubes 8.4 are inserted into the placing holes 8.3, in this embodiment, the number of the placing holes 8.3 is six, six serum sample test tubes 8.4 are correspondingly placed, serum samples are filled in the serum sample test tubes 8.4, two pairs of elastic clamping pieces 8.5 are integrally formed on one side of the sample mounting frame 8 facing the central part of the large plate 2.1, a clamping groove 8.6 is formed between each pair of elastic clamping pieces 8.5, the clamping groove 8.6 is in inserting fit with the edge of the large plate 2.1, and the sample test tubes are elastically clamped and fixed on the edge of the large plate 2.1 through the two pairs of elastic clamping pieces 8.5.

As shown in fig. 6, a conveying rack 14 is fixedly arranged on the bottom plate 1.2, the conveying rack 14 includes a third side plate 14.1 and a transverse mounting seat 14.2, the third side plate 14.1 is vertically fixed on the surface of the bottom plate 1.2, and the top of the third side plate is fixedly connected with the bottom surface of the transverse mounting seat 14.2, the conveying rack 14 and the second side plate 1.10 are respectively located on two opposite sides of the first carrier table 1.3 (see fig. 1), the third side plate 14.1 is parallel to the first side plate 1.1, a channel 14.3 is formed between the first side plate 1.1 and the third side plate 14.1, a track plate 14.4 extending along the width direction of the bottom plate 1.2 is arranged in the channel 14.3, two sides of the track plate 14.4 are respectively fixedly connected with the outer side surface of the second carrier table 1.4 and the third side plate 14.1, two track plates 14.5 extending along the length direction of the track plate 14.4 are fixedly arranged on the surface of the track plate 14.4, a first slide rail 14.5 is slidably fitted with a slide rail 14.6, and a suction nozzle 14.6 is, the first rail slider 14.7 is provided with a first sliding groove 14.8 slidably engaged with the first sliding rail 14.5, as shown in fig. 7 and 8, the surface of the rail plate 14.4 is provided with a first elongated groove 14.9 penetrating to the bottom surface of the rail plate 14.4, and the first elongated groove 14.9 is disposed to extend along the length direction of the rail plate 14.4. Referring to fig. 7 and 8, a first extending block 14.10 passing through the first elongated slot 14.9 and protruding from the bottom surface of the track plate 14.4 is fixedly disposed at the bottom of the nozzle rack 14.6, a first limiting block 14.11 detachably mounted at the bottom of the first extending block 14.10 through a first bolt 14.12 is disposed at one end of the first extending block 14.10, which is away from the nozzle rack 14.6, and a threaded hole (not shown in the figure) in threaded engagement with the first bolt 14.12 is disposed at the bottom of the first extending block 14.10.

As shown in fig. 7 and 8, a sixth driving mechanism 15 for driving the nozzle placement frame 14.6 to slide on the first sliding rail 14.5 is disposed on the bottom surface of the rail plate 14.4, the sixth driving mechanism 15 includes a sixth driving motor 15.1 and a sixth pulley assembly 15.2, the sixth driving motor 15.1 is fixedly mounted on the ground of the rail plate 14.4, the sixth pulley assembly 15.2 includes a sixth driving wheel 15.3, a sixth driven wheel 15.4 and a sixth belt 15.5, the sixth driving wheel 15.3 is coaxially fixed with the motor shaft of the sixth driving motor 15.1, the sixth driven wheel 15.4 is rotatably mounted at the bottom of the rail plate 14.4, the sixth belt 15.5 is annular, two ends of the sixth driving wheel 15.3 and the sixth driven wheel 15.4 are sleeved, the first stopper 14.11 is matched with the first extension block 14.10 to clamp and fix the sixth belt 15.5 therein, the first bolt 14.12 passes through the first stopper 14.11 from high to high and is matched with a threaded hole at the bottom of the first extension block 14.10, through screwing up first bolt 14.12, realize the fixed connection of first extension piece 14.10 and sixth belt 15.5, sixth belt 15.5 transmission drives suction nozzle rack 14.6 through first stopper 14.11 and first extension piece 14.10 and removes.

Referring to fig. 9, the nozzle placement rack 14.6 is provided with a plurality of nozzle placement holes 15.6, the nozzle placement holes 15.6 are distributed in an array along the length and width directions of the nozzle placement rack 14.6, and each nozzle placement hole 15.6 is inserted with a nozzle 15.7.

As shown in fig. 9 and 10, the transverse mounting seat 14.2 extends along the length direction of the bottom plate 1.2, and the bottom surface of the transverse mounting seat is fixedly connected to the surface of the second bearing table 1.4, one side of the transverse mounting seat 14.2 is fixedly provided with a short-stroke rail 15.8 extending along the length direction of the transverse mounting seat 14.2, the short-stroke rail 15.8 is located at one side of the second bearing table 1.4, the short-stroke rail 15.8 includes two second slide rails 15.9 extending along the length direction of the transverse mounting seat 14.2, the second slide rails 15.9 are slidably mounted with the sample filling mechanism 16, one side of the sample filling mechanism 16 is fixedly provided with a connecting pad 16.1, the connecting pad 16.1 is fixedly provided with a second rail slider 16.2, the second rail slider 16.2 is provided with a second sliding groove 16.3 slidably engaged with the second slide rail 15.9, and the sample filling mechanism 16 slides on the transverse mounting seat 14.2 through the second slide rails 15.9.

As shown in fig. 10 and 11, a second elongated groove 16.4 extending along the length direction of the transverse mounting seat 14.2 is formed in a surface of the transverse mounting seat 14.2 facing the connecting pad 16.1 in a penetrating manner, a second extending block 16.5 is fixedly arranged on a side surface of the connecting pad 16.1, the first extending block 14.10 penetrates through the second elongated groove 16.4, and one penetrating end of the first extending block protrudes out of a side of the transverse mounting seat 14.2 facing away from the connecting pad 16.1, and a second limiting block 16.7 detachably mounted at the bottom of the second extending block 16.5 through a second bolt 16.6 is arranged at one end of the second extending block 16.5 facing away from the connecting pad 16.1. A seventh driving mechanism 16.8 for driving the sample filling mechanism 16 to slide on the second sliding rail 15.9 is fixedly arranged on the transverse mounting seat 14.2, the seventh driving mechanism 16.8 includes a seventh driving motor 16.9 and a seventh pulley assembly 16.10, the seventh driving motor 16.9 is fixedly arranged on the transverse mounting seat 14.2, an axis of a motor shaft of the seventh driving motor 16.9 is perpendicular to the surface of the second bearing table 1.4, the seventh pulley assembly 16.10 includes a seventh driving wheel 16.11, two seventh driven wheels 16.12 and a seventh belt 16.13, the seventh driving wheel 16.11 is coaxially fixed on the motor shaft of the seventh driving motor 16.9, the two seventh driven wheels 16.12 are rotatably arranged on the surface of the transverse mounting seat 14.2 parallel to the second bearing table 1.4, the two seventh driving wheels 16.11 are distributed at two end portions of the transverse mounting seat 14.2, the seventh belt 16.13 is sleeved on the seventh driving wheel 16.11 and the two seventh driven wheels 16.12, the seventh driving wheel 16.11 and the seventh driven wheel 16.12 are driven, a section of the seventh belt 16.13 located between the two seventh driven wheels 16.12 faces the second elongated groove 16.4, a threaded hole (not shown in the figure) in threaded connection with the second bolt 16.6 is formed in the end surface of the second extending block 16.5, the seventh belt 16.13 is installed between the second limiting block 16.7 and the second extending block 16.5, the second bolt 16.6 penetrates through the second limiting block 16.7 and then is in threaded fit with the threaded hole in the second extending block 16.5, the second bolt 16.6 is screwed, the seventh belt 16.13 is fixed between the second limiting block 16.7 and the second extending block 16.5, the seventh belt 16.13 is driven, and the sample filling mechanism 16 is driven to slide on the second slide rail 15.9 by the second limiting block 16.7 and the second extending block 16.5.

As shown in fig. 11 and 12, the sample filling mechanism 16 comprises a work box 16.14, a second injector 16.15 and an injection control assembly 16.16 for drawing liquid into the second injector 16.15 or pushing liquid out of the second injector 16.15, and a lifting drive assembly 16.17 for driving the second injector 16.15 and the injection control assembly 16.16 to lift, wherein the work box 16.14 is shaped like a rectangular parallelepiped, and one side of the work box 16.14 is fixedly connected with a connecting pad plate 16.1; the lifting driving assembly 16.17 comprises a moving driving motor 16.18 and a second ball screw pair 16.19, the moving driving motor 16.18 is fixedly arranged at the top outside the working box 16.14, a motor shaft extends into the working box 16.14 and is coaxially fixed with a second ball screw pair 16.19 in the working box 16.14, two ends of a screw shaft on the second ball screw pair 16.19 are respectively and rotatably connected with two ends of the working box 16.14 through bearings, a ball nut 16.30 on the second ball screw pair 16.19 is lifted and moved on the screw shaft, a linkage plate 16.20 is fixedly arranged on the ball nut 16.30 of the second ball screw pair 16.19, the linkage plate 16.20 is parallel to the inner bottom surface of the working box 16.14, a fifth guide rod 16.21 extending along the height direction of the working box 16.14 is arranged in the working box 16.14, an embedding hole 16.22 is arranged on the surface of the linkage plate 16.20 in a penetrating way, a guide shaft sleeve 16.23 is arranged on the embedding hole 16.22, a fifth guide rod 16.21 is slidably sleeved with a fifth guide rod 16.16.16.22, the moving driving motor 16.18 drives the second ball screw pair 16.19 to work, and drives the linkage plate 16.20 to lift in the working box 16.14 along the height direction of the working box 16.14.

As shown in fig. 12, the injection control assembly 16.16 includes a control motor 16.25 and a control screw 16.26, the control motor 16.25 is fixedly installed on one side of the linkage plate 16.20 facing the inner bottom surface of the working box 16.14, a circular hole 16.28 is formed in the surface of the linkage plate 16.20, a motor shaft of the control motor 16.25 passes through the circular hole 16.28 and then is coaxially fixed with one end of the control screw 16.26, a telescopic guide rod 16.29 is coaxially fixed at the other end of the control screw 16.26, the upper end of the telescopic guide rod 16.29 is in up-and-down sliding fit with a hole in the working box 16.14, a ball nut 16.38 is sleeved on the control screw 16.26, a driving block 16.31 is fixedly connected on the ball nut 16.38, a sixth guide hole 16.32 is formed on the driving block 16.31, the sixth guide hole 16.32 is in up-and-down sliding fit with a hole on the working box 16.14, the control motor 16.25 is located between a second ball screw pair 16.19 and a fifth guide rod 16.21, the control motor 16.25 works, and drives the ball screw, during the lifting process, the fifth guide rod 16.21 is matched with the sixth guide hole 16.32 in a sliding mode.

As shown in fig. 12 and 13, the second injector 16.15 includes a syringe barrel 16.33, a piston 16.34 located in the syringe barrel 16.33, and an injection rod 16.35 with one end fixedly connected with the piston 16.34, the piston 16.34 and the injection rod 16.35 are installed in the syringe barrel 16.33 from one end of the syringe barrel 16.33, the other end of the syringe barrel 16.33 is plugged with the suction nozzle 15.7, the interior of the injection cylinder body 16.33 is communicated with the suction nozzle 15.7, the inner bottom surface of the working box 16.14 is provided with a moving hole 16.36 in a penetrating way, the injection cylinder body 16.33 passes through the moving hole 16.36, and extends out of the bottom of the work box 16.14, the injection cylinder 16.33 can move up and down in the moving hole 16.36, one end of the injection cylinder 16.33 is fixedly connected with the bottom surface of the linkage plate 16.20, the injection rod 16.35 is positioned in the work box 16.14, and one end of the injection cylinder body 16.33 is fixedly connected with the driving block 16.31 after passing through the linkage plate 16.20, the surface of the linkage plate 16.20 is provided with a connecting hole 16.37 for the injection rod 16.35 to pass through, and the injection rod 16.35 can move up and down in the connecting hole 16.37.

As shown in fig. 9 to 13, the movement driving motor 16.18 operates to drive the linkage plate 16.20 to lift through the second ball screw pair 16.19, so as to drive the second injector 16.15 and the control motor 16.25 to lift, and the injection cylinder 16.33 of the second injector 16.15 lifts up and down in the movement hole 16.36, so as to realize the lifting of the second injector 16.15 on the sample filling mechanism; the motor 16.25 is controlled to work, the driving block 16.31 is driven to lift through the control screw rod 16.26 and the ball nut 16.30 on the control screw rod 16.26, in the lifting process, the driving block 16.31 is close to or far away from the linkage plate 16.20, the driving block 16.31 drives the injection rod 16.35 to move up and down in the injection cylinder body 16.33, and therefore the use of the second injector 16.15 is achieved, liquid substances in the second injector 16.15 are injected out, or the liquid substances are injected into the second injector 16.15.

As shown in fig. 6 to 13, the sample filling mechanism moves horizontally on the transverse mounting seat 14.2 through the short-stroke track 15.8, when the sample filling mechanism moves to the position above the nozzle placement rack 14.6, the movement driving motor 16.18 in the sample filling mechanism works to drive the syringe barrel 16.33 on the second injector 16.15 to descend for a certain height, one end of the syringe barrel 16.33 is inserted into the nozzle 15.7 placed on the nozzle placement rack 14.6, the nozzle 15.7 is installed at one end of the syringe barrel 16.33, after the installation is finished, the syringe barrel 16.33 on the second injector 16.15 rises and resets, then the sample filling mechanism moves to the edge of the large plate 2.1, the large plate 2.1 rotates to enable the serum sample test tube 8.4 to be opposite to the nozzle 15.7 on the second injector 16.15 up and down for a certain height again, the nozzle 15.7 on the second injector 16.15 extends into the serum sample test tube 8.4, and the operation control motor 16.25, the second syringe 16.15 is controlled to suck the serum sample liquid in the serum sample test tube 8.4 into the second syringe 16.15, and then the syringe barrel 16.33 on the second syringe 16.15 is lifted and reset.

The working principle of the embodiment is as follows: the used suction nozzle 15.7 on the second injector 16.15 is removed, then the sample filling mechanism 16 moves transversely to the position above the suction nozzle 15.7 placing rack 14.6, the second injector 16.15 is driven to descend for a certain height by the lifting drive assembly 16.17, one end of the second injector 16.15 is in plug-in fit with the suction nozzle 15.7 on the suction nozzle 15.7 placing rack 14.6, the unused suction nozzle 15.7 is installed on the second injector 16.15, the new suction nozzle 15.7 is replaced on the second injector 16.15, the suction nozzle 15.7 on the sample filling mechanism 16 is replaced quickly, the new unused suction nozzle 15.7 is adopted to suck different samples, and the cross contamination is prevented.

The embodiment of this specific implementation mode is the preferred embodiment of the present invention, not limit according to this the utility model discloses a protection scope, so: all equivalent changes made according to the structure, shape and principle of the utility model are covered within the protection scope of the utility model.

Claims

1. A suction nozzle replacing structure on a full-automatic immunoblotting instrument comprises a frame (1), wherein a sample box (8.2) is arranged on the frame (1), it is characterized in that a big disc (2.1) is arranged on the frame (1) in a rotating way, the sample box (8.2) is arranged on the big disc (2.1), a suction nozzle placing frame (14.6) is arranged on one side of the rack (1) positioned on the large disc (2.1), a suction nozzle (15.7) is arranged on the suction nozzle placing frame (14.6), a sample filling mechanism (16) which transversely reciprocates between the large disc (2.1) and the suction nozzle placing frame (14.6) is arranged on the rack (1), the sample filling mechanism (16) comprises a second injector (16.15) and a lifting driving component (16.17) for driving the second injector (16.15) to lift, after the second injector (16.15) descends to a certain height, one end of the second injector is in plug-in fit with a suction nozzle (15.7) on the suction nozzle placing rack (14.6).

2. The suction nozzle replacing structure of the fully automatic immunoblotting instrument according to claim 1, wherein: the second injector (16.15) comprises a syringe barrel (16.33), the syringe barrel (16.33) is provided with a plug port which is detachably plugged and matched with the suction nozzle (15.7), and the plug port is communicated with the interior of the syringe barrel (16.33).

3. The suction nozzle replacing structure of the fully automatic immunoblotting instrument according to claim 2, wherein: the second injector (16.15) further comprises a piston (16.34) in sliding fit with the injection cylinder body (16.33), an injection rod (16.35) with one end fixedly connected with the piston (16.34), and the sample filling mechanism (16) further comprises an injection control assembly (16.16) for driving the injection rod (16.35) to move in the injection cylinder body (16.33).

4. The suction nozzle replacing structure of the fully automatic immunoblotting instrument according to claim 1, wherein: the lifting driving assembly (16.17) comprises a moving driving motor (16.18), a second ball screw pair (16.19) and a linkage plate (16.20), the second injector (16.15) is installed on the linkage plate (16.20), and the moving driving motor (16.18) drives the second ball screw pair (16.19) to work so as to drive the second injector (16.15) on the linkage plate (16.20) to lift.

5. The suction nozzle replacing structure of the fully automatic immunoblotting instrument according to claim 1, wherein: be provided with short stroke track (15.8) on frame (1), short stroke track (15.8) include along second slide rail (15.9) that frame (1) length direction extends, be provided with on sample filling mechanism (16) and slide the second groove (16.3) that slides complex with second slide rail (15.9).

6. The suction nozzle replacing structure of the fully automatic immunoblotting instrument according to claim 5, wherein: and a seventh driving mechanism (16.8) for driving the sample filling mechanism (16) to slide on the second sliding rail (15.9) is arranged on the rack (1).

7. The suction nozzle replacing structure of the fully automatic immunoblotting instrument according to claim 6, wherein: the seventh driving mechanism (16.8) comprises a seventh driving motor (16.9) and a seventh belt pulley assembly (16.10), and the seventh driving motor (16.9) drives the sample filling mechanism (16) to move on the second track through the seventh belt pulley assembly (16.10).

8. The suction nozzle replacing structure of the fully automatic immunoblotting instrument according to claim 1, wherein: and a sixth driving mechanism (15) for driving the suction nozzle placing frame (14.6) to move along the width direction of the rack (1) is arranged on the rack (1).

9. The suction nozzle replacing structure of the fully automatic immunoblotting instrument according to claim 8, wherein: the sixth driving mechanism (15) comprises a sixth driving motor (15.1) and a sixth belt pulley assembly (15.2), and the sixth driving motor (15.1) drives the suction nozzle placing frame (14.6) to move along the width direction of the rack (1) through the sixth belt pulley assembly (15.2).