CN212476731U

CN212476731U - Disposable virus sampling tube

Info

Publication number: CN212476731U
Application number: CN202020325511.1U
Authority: CN
Inventors: 车翔林
Original assignee: Union Hospital Tongji Medical College Huazhong University of Science and Technology
Current assignee: Union Hospital Tongji Medical College Huazhong University of Science and Technology
Priority date: 2020-03-16
Filing date: 2020-03-16
Publication date: 2021-02-05
Anticipated expiration: 2030-03-16

Abstract

The utility model discloses a disposable virus sampling tube, which comprises a storage tube, wherein the storage tube comprises a first tube body, a second tube body is arranged above one side of the first tube body, the lower end of the second tube body is communicated with the first tube body, and the upper end of the second tube body is provided with a cover; the first body opposite side is equipped with sampling mechanism, still be equipped with in the first body and preserve liquid. The utility model discloses a sampling mechanism's sheet rubber inserts the sampling and detects, need not to unscrew the lid, and aerosol overflows and the interior liquid leaks out when avoiding uncapping, reduces the risk that testing personnel infects the virus, has reduced numerous and complex operations simultaneously, practices thrift a large amount of check-out time. A swab pole portion that is used for the sampling is close to the swab head in addition and is equipped with the rupture pole, and when the swab was put into from second body upper end, the swab of being convenient for break and make the swab head drop to first body in, the release rate of virus is improved to the virus sample and the save liquid intensive mixing of assurance swab head, makes and finally can obtain better effect to detect.

Description

Disposable virus sampling tube

Technical Field

The utility model relates to a sampling device belongs to the virus detection area, especially a disposable virus sampling pipe.

Background

The detection of viruses is an important subject to be faced in medicine, and the current sample collection methods related to viral diseases are not uniform, so that the overall detection result is not ideal. The more common way is to extract secretions, such as those transmitted through the respiratory tract, pharyngeal and nasal secretions; or contact transmitted, such as genital tract secretions, by analyzing the components of the secretions to determine the viral species. The virus sampling tube is a device specially designed for collecting and storing secretions, and the secretions are dipped by a swab and put into the sampling tube to wait for inspection. The existing virus sampling tube has certain problems in the using process, and the most prominent problem is that the safety of detection personnel is not considered. On one hand, aerosol transmission possibility (such as influenza virus) exists for airborne infectious viruses, and the existing virus sampling tube is opened for detection after sampling, so that infection is easy to occur; secondly, for infectious viruses (such as human papilloma viruses) which are transmitted in a contact manner, when a detector opens a sampled virus sampling tube, liquid is easy to leak, so that the infection risk of the detector is increased; thirdly, for infectious viruses, the detection time is increased by requiring the detection personnel to operate gently and open the virus sampling tube, which violates the purposes that the epidemic situation is a command and the time is the life. On the other hand, the release rate of the sampling swab is too low, namely when the nasopharynx sampling is carried out, the swab head is put into the sampling liquid, and the shaking virus particles are still difficult to enter the sampling liquid, so the virus nucleic acid positive rate and the separation positive rate are reduced, and more false negative is generated.

SUMMERY OF THE UTILITY MODEL

An object of the utility model is to overcome prior art not enough, provide a disposable virus sampling pipe to solve the problem that proposes in the above-mentioned technical background.

In order to achieve the above object, the present invention provides a method for manufacturing a semiconductor device, comprising:

the disposable virus sampling tube comprises a storage tube, wherein the storage tube comprises a first tube body, a second tube body is arranged above one side of the first tube body, the lower end of the second tube body is communicated with the first tube body, and a cover is arranged at the upper end of the second tube body; the first body opposite side is equipped with sampling mechanism, still be equipped with in the first body and preserve liquid.

In the technical scheme, a grid is vertically arranged in the first pipe body, the upper end and the lower end of the grid are respectively and correspondingly fixedly connected with the upper end surface and the lower end surface of the first pipe body, the space in the first pipe body is divided into two parts, one part is communicated with the second pipe body, and the other part is internally provided with a sampling mechanism;

a plurality of glass elution beads are arranged in the space part which is communicated with the second tube body in the first tube body.

In the technical scheme, the sampling mechanism comprises a cylinder body and a rubber sheet, the upper end of the cylinder body is fixedly connected with the upper end face of the first pipe body, and the distance H between the lower end face of the cylinder body and the lowest point of the inner bottom face of the first pipe body is 4-6 mm;

the space in the cylindrical body forms a hollow tube, one end of the hollow tube, which is close to the upper end face of the first tube body, extends to the outside, and an easily-torn sealing film is arranged at the communication part of the hollow tube and the outside and on the upper end face of the first tube body; the hollow pipe is communicated with the first pipe body at one end close to the inner bottom surface of the first pipe body, the inner diameter of the hollow pipe is sequentially reduced from top to bottom, the rubber sheet is further arranged at one end close to the inner bottom surface of the first pipe body in the hollow pipe, and the periphery of the rubber sheet is embedded on the cylindrical body.

In the technical scheme, one end of the cylinder body, which is close to the inner bottom surface of the first pipe body, is horizontally provided with the annular groove, the rubber sheet is embedded in the annular groove, and the diameter D of the rubber sheet is larger than the outer diameter D of the annular groove.

In the technical scheme, the thickness of the rubber sheet is 2 mm.

In the technical scheme, the center of the rubber sheet is provided with a cross crack which penetrates or does not penetrate through the inner surface of the rubber sheet contacted with the preservation solution.

In the above technical scheme, a sealing ring is arranged at the top of the inner side of the cover and used for sealing a joint surface of the inner side of the cover and the upper top surface of the second pipe body, and the sealing ring is made of silica gel.

In the technical scheme, the inner wall of the cover is provided with the annular protrusion for increasing the friction force between the outer wall of the upper end of the second pipe body and the cover.

In the technical scheme, the swab for sampling is further included, at least one section of breaking rod is arranged at the end, close to the head end of the swab, of the rod part of the swab, and the material of the rod part is polypropylene containing nylon fibers.

In the technical scheme, the swab head is made of artificial fibers.

Compared with the prior art, the beneficial effects of the utility model are that:

1. the pre-marked mark in the rubber sheet of the sampling mechanism is beneficial to the sample adding gun to easily pierce the rubber sheet; after sampling, the rubber sheet of the sampling mechanism elastically retracts to close the sampling port, so that the internal liquid is prevented from leaking outside, and the time for screwing back the cover after the cover of the conventional virus sampling pipe is opened is saved; meanwhile, the sampling mechanism is provided with an easily torn sealing film at the opening part, so that the pollution of the sampling mechanism can be prevented, a sampling channel is opened by tearing the sealing film, the existing virus sampling pipe uncovering operation is replaced, the infection risk caused by uncovering is avoided, and the uncovering time is saved.

2. The utility model discloses in, set up sampling mechanism on the lid of virus sampling pipe, insert the sampling through sampling mechanism's sheet rubber and detect, need not to unscrew the lid, aerosol spills over and the inner liquid leaks out when avoiding uncapping, reduces the risk that testing personnel infects the virus, has reduced numerous and complicated operations simultaneously, practices thrift a large amount of check-out time.

3. The swab pole portion is close to the rupture pole that the swab head was equipped with, and when the swab was put into from second body upper end, the swab of being convenient for break and make the swab head drop to first body in, the virus sample of guaranteeing the swab head with preserve liquid intensive mixing, improve the release rate of virus, make detect finally can obtain better effect.

4. Be provided with a plurality of glass elution pearl in first body pipe, need vibrate in the use and make the virus sample fully release, can make the release rate of virus enlarge several times after adding a plurality of glass elution pearl, avoided influencing the condition of testing result because of the virus release rate is low excessively.

Drawings

FIG. 1 is a schematic structural view of example 1;

FIG. 2 is a sectional view of embodiment 1;

FIG. 3 is an enlarged view of a portion of FIG. 2 at A;

FIG. 4 is a sectional view of a sampling mechanism in example 1;

FIG. 5 is a schematic view showing the structure of a rubber sheet in example 1;

FIG. 6 is a schematic view showing the structure of the swab of embodiment 1;

FIG. 7 is a schematic sampling diagram of example 1;

FIG. 8 is a sectional view of embodiment 2;

in the figure, the position of the upper end of the main shaft,

1. a first pipe body; 1.1, an arc bottom; 1.2, supporting the bottom ring; 2. a second tube body; 3. a cover; 4. a sampling mechanism; 4.1, a cylindrical body; 4.2, rubber sheets; 4.3, hollow tube; 4.4, an annular groove; 5. preserving fluid; 6. a grid; 7. glass washing beads; 8. a swab; 8.1, breaking the rod.

H: the distance between the lower end surface (or the end surface provided with one end of the rubber sheet) of the cylinder body and the lowest point of the inner bottom surface (or the lowest point of the inner surface of the arc bottom) of the first pipe body;

h: the distance between the end surface of one end of the cylinder body, provided with the rubber sheet, and the highest point of the inner surface of the arc bottom is shorter than the distance between the end surface of the end of the cylinder body and the highest point of the inner surface of the arc bottom;

d: the diameter of the rubber sheet;

d: the outer diameter of the annular groove;

l: the distance between the rubber sheet and the end face of the cylinder body close to one end of the rubber sheet.

Detailed Description

The following description of the embodiments of the present invention is provided for illustrative purposes, and other advantages and effects of the present invention will be readily apparent to those skilled in the art from the disclosure herein. The present invention can also be implemented or applied through other different specific embodiments, and various details in the present specification can be modified or changed based on different viewpoints and applications without departing from the spirit of the present invention. It is to be noted that the features in the following embodiments and examples may be combined with each other without conflict.

It should be noted that the drawings provided in the following embodiments are only for illustrating the basic concept of the present invention, and the components related to the present invention are only shown in the drawings rather than drawn according to the number, shape and size of the components in actual implementation, and the form, amount and ratio of the components in actual implementation may be changed at will, and the layout of the components may be more complicated.

Example 1

Referring to fig. 1 to 7, the present embodiment provides a disposable virus sampling tube, including a storage tube, where the storage tube includes a first tube body 1, a second tube body 2 is disposed above one side of the first tube body 1, a lower end of the second tube body 2 is communicated with the first tube body 1, and a cap 3 is disposed at an upper end of the second tube body 2; the 1 opposite side of first body is equipped with sampling mechanism 4, still be equipped with in the first body 1 and preserve liquid 5. The preservation solution 5 is a reagent for preserving a virus sample in the prior art, for example, a virus sampling solution provided by patent publication No. CN101979516A under the patent name, and comprises the following components: 2-4% of trehalose, 2-4% of bovine serum albumin, 1-3% of dextran, 1% of sodium glutamate, 1-2% of gelatin, 1-3% of glycine and 2% of sucrose.

Referring to fig. 2 and 4, the sampling mechanism 4 includes a cylinder body 4.1 and a rubber sheet 4.2, the upper end of the cylinder body 4.1 is fixedly connected to the upper end surface of the first pipe body 1, and a distance H between the lower end surface of the cylinder body 4.1 and the lowest point of the inner bottom surface of the first pipe body 1 is 4mm to 6mm, preferably 5 mm;

the space in the cylinder body 4.1 forms a hollow tube 4.3, one end of the hollow tube 4.3, which is close to the upper end face of the first tube body 1, extends to the outside, and an easy-to-tear sealing film is arranged at the communication part of the hollow tube 4.3 and the outside and on the upper end face of the first tube body, so that the easy-to-tear sealing film can prevent the pollution of the sampling mechanism 4 and is convenient for sampling operation; one end of the hollow tube 4.3 close to the inner bottom surface of the first tube body 1 is communicated with the first tube body 1, the inner diameter of the hollow tube 4.3 is sequentially reduced from top to bottom, the rubber sheet 4.2 is further arranged at one end of the hollow tube 4.3 close to the inner bottom surface of the first tube body 1, and the periphery of the rubber sheet 4.2 is embedded on the cylindrical body 4.1. Further, cylinder body 4.1 is close to first body 1 in bottom surface one end level be equipped with annular groove 4.4, be equipped with in the annular groove 4.4 and inlay and be equipped with sheet rubber 4.2, and sheet rubber 4.2's diameter D is greater than annular groove 4.4's external diameter D, is convenient for have the elastic rubber piece closely impress in annular groove 4.4, and it leaks to seal to prevent to preserve liquid 5 in the first body 1.

Further, referring to fig. 2, the bottom end of the first pipe body 1 is an arc-shaped bottom 1.1, the lowest point of the inner surface of the arc-shaped bottom 1.1 is right opposite to the center of a rubber sheet 4.2 in the sampling mechanism 4, the distance between the end surface of the end of the cylinder body 4.1, provided with the rubber sheet 4.2, and the lowest point of the inner surface of the arc-shaped bottom 1.1 is H, and the distance between the end surface of the end of the cylinder body 4.1, provided with the rubber sheet 4.2, and the highest point of the inner surface of the arc-shaped bottom 1.1 is H; wherein the value range of H is 4mm-6mm, and the value range of H is 1mm-3 mm.

The bottom end of the first pipe body 1 is further provided with a supporting bottom ring 1.2, and the supporting bottom ring 1.2 is located on the periphery of the arc-shaped bottom 1.1 and is fixedly connected with the pipe wall of the pipe body 5. The distance between the lowest point of the outer surface of the arc bottom 1.1 and the lower end face of the supporting bottom ring 1.2 is 1mm-3mm, so that the first pipe body 1 is stably placed on a table top through the supporting bottom ring 1.2, and the problem that a virus sampling pipe is unstable due to the fact that the table top is slightly uneven to support the arc bottom 1.1 can be avoided.

In this embodiment, the rubber sheet 4.2 is made of butyl rubber or polyisoprene rubber. The thickness of the rubber sheet 4.2 is 2 mm. Referring to fig. 5, the rubber sheet 4.2 has a cross-shaped fracture 4.2a in the center, and the cross-shaped fracture 4.2a penetrates or does not penetrate the inner surface of the rubber sheet 4.2 contacting the preservation fluid 5, preferably does not penetrate. The cross-shaped crack 4.2a is beneficial to the sample adding gun to easily pierce the rubber sheet 4.2 for sampling, the easily torn sealing film is torn off during sampling, and the sample adding gun is inserted into the cross-shaped crack 4.2a of the rubber sheet 4.2 for sampling; after sampling, the cross crack 4.2a of the sampling sheet is elastically retracted to close the sampling port, so that the sample is prevented from leaking from the cross crack 4.2 a.

Furthermore, the inner diameter of one end of the hollow tube 4.3 is 1.5-2.5 times of the inner diameter of the other end, for example, the inner diameter of one end of the hollow tube 4.3 is 5mm-6mm, and the inner diameter of the other end is 2.5mm-4 mm; the distance L between the rubber sheet 4.2 and the end face of the cylindrical body 4.1 close to one end of the rubber sheet 4.2 is 1mm-3 mm.

Referring to fig. 3, a sealing ring 3.1 is arranged at the top of the inner side of the cover 3, the sealing ring 3.1 is used for sealing a joint surface between the inner side of the cover 3 and the upper top surface of the second pipe body 2, and the sealing ring 3.1 is made of silica gel. Be provided with the annular arch 3.2 that is used for increasing frictional force between second body 2 and the lid 3 on the inner wall of lid 3, annular arch 3.2 is located sealing washer 3.1 below, increases the frictional force between 2 upper end outer walls of second body and the lid 3, prevents to have the preservative solution to reveal oscillating the in-process.

Referring to fig. 7, the utility model also comprises a swab 8 for sampling, the rod part of the swab 8 is provided with at least one section of breaking rod 8.1 near the head end of the swab, and the material of the rod part is polypropylene containing nylon fiber. The material of the swab head is artificial fiber.

Further, the size and material of the disposable virus collection tube provided in this embodiment are exemplified as follows: the diameter of the first pipe body 1 is 18mm and 55mm, the diameter of the second pipe body 2 is 9mm and 15mm, and the wall thickness of the first pipe body and the second pipe body is 1 mm.

The outer diameter of the cylinder body 4.1 is 6mm and the height is 12mm, the distance D from the lower end of the cylinder body 4.1 to the inner bottom surface of the first pipe body 1 is 3mm, the inner diameter of the upper end of a hollow pipe in the cylinder body 4.1 is 5mm, and the inner diameter of the lower end is 3 mm; the diameter of cylinder body 4.1 is 4mm, the diameter of sheet rubber 4.2 is greater than the external diameter of annular groove.

The first pipe body 1, the second pipe body 2 and the cylinder body 4.1 are all made of polypropylene materials and are integrally formed, and during assembly, the rubber sheet 4.2 with elasticity is pressed downwards into the annular groove 4.4 from the upper end (the end with the large diameter) of the hollow pipe in the cylinder body 4.1.

In this embodiment, the diameter of first body 1 is less than the diameter of first body 2, and first body is used for putting into swab 8 after the sampling to be convenient for break swab 8, make the swab head after the sampling fall into first body 1, save in the first body 1 and preserve liquid 5, and the diameter of first body is greater than the second body, and the swab head of being convenient for break shakes in first body, makes the viral particle get into more easily and preserves liquid.

The use method of the disposable virus sampling tube provided in this example 1 is as follows: when a sample is collected, the cover 3 is opened, the swab 8 after sampling is placed from the second pipe body 2, the swab 8 and the second pipe body 2 are inclined so as to break the swab 8 from a breaking rod 8.1 arranged on the rod part of the swab 8 (see fig. 7), the head part of the swab after sampling falls into the first pipe body 1 and is immersed into the preservation solution 5, and the head part of the swab is fully shaken to be mixed with the preservation solution so that virus particles enter the preservation solution; during sampling, the easily torn sealing film is torn off, and then a sampling gun head is inserted from the cross crack 4.2a of the rubber sheet 4.2 of the sampling mechanism 4 for sampling and testing.

In this embodiment, set up sampling mechanism 4 on the lid 3 of virus sampling pipe, insert the sampling through 4.2 of the rubber sheet of sampling mechanism 4 and detect, need not to unscrew lid 3, and aerosol overflows and the inner liquid leaks out when avoiding uncapping, reduces the risk that testing personnel infects the virus, has reduced numerous and complicated operations simultaneously, practices thrift a large amount of check-out time.

Meanwhile, the cross-shaped crack 4.2a in the rubber sheet 4.2 of the sampling mechanism 4 is beneficial to the sample adding gun to easily pierce the rubber sheet 4.2 for sampling, and after sampling, the rubber sheet 4.2 elastically retracts to close the sampling opening, so that the inner liquid is prevented from leaking outside, and meanwhile, the time for screwing back the cover 3 after the cover of the existing virus sampling tube is opened is saved.

Example 2

The structure of this embodiment is similar to that of embodiment 1, and the difference is that, referring to fig. 8, a grid 6 is vertically arranged in the first pipe 1, the upper end and the lower end of the grid 6 are respectively and correspondingly fixedly connected with the upper end face and the lower end face of the first pipe 1, and the space in the first pipe 1 is divided into two parts, one part of which is communicated with the second pipe 2, and the other part of which is provided with a sampling mechanism 4;

a plurality of glass elution beads 7 are provided in the space portion in the first pipe body 1 communicating with the second pipe body 2. The diameter of the glass elution beads 7 is larger than the diameter of the meshes of the grid 6, preventing the glass elution beads 7 from being immersed under the sampling mechanism 4.

In this embodiment, be provided with a plurality of glass elution pearl in first body 1, need vibrate in the use and make the virus sample fully release, can make the release rate of virus enlarge several times after adding a plurality of glass elution pearl, avoided influencing the condition of testing result because of the virus release rate is low excessively.

The above-mentioned embodiments only express the specific embodiments of the present invention, and the description thereof is specific and detailed, but not construed as limiting the scope of the present invention. It should be noted that, for those skilled in the art, without departing from the spirit of the present invention, several variations and modifications can be made, which are within the scope of the present invention.

Claims

1. The disposable virus sampling tube comprises a storage tube and is characterized in that the storage tube comprises a first tube body (1), a second tube body (2) is arranged above one side of the first tube body (1), the lower end of the second tube body (2) is communicated with the first tube body (1), and a cover (3) is arranged at the upper end of the second tube body (2); first body (1) opposite side is equipped with sampling mechanism (4), still be equipped with in first body (1) and preserve liquid (5).

2. The disposable virus sampling tube according to claim 1, wherein a grid (6) is vertically arranged inside the first tube body (1), the upper end and the lower end of the grid (6) are respectively and correspondingly fixedly connected with the upper end surface and the lower end surface of the first tube body (1), and the space in the first tube body (1) is divided into two parts, one part is communicated with the second tube body (2), and the other part is internally provided with a sampling mechanism (4);

a plurality of glass elution beads (7) are arranged in the space part which is communicated with the second pipe body (2) in the first pipe body (1).

3. The disposable virus sampling tube according to claim 1 or 2, wherein the sampling mechanism (4) comprises a cylindrical body (4.1) and a rubber sheet (4.2), the upper end of the cylindrical body (4.1) is fixedly connected with the upper end surface of the first tube body (1), the distance H between the lower end surface of the cylindrical body (4.1) and the lowest point of the inner bottom surface of the first tube body (1) is 4mm-6 mm;

the space in the cylindrical body (4.1) forms a hollow tube (4.3), one end, close to the upper end face of the first tube body (1), of the hollow tube (4.3) extends to the outside, and an easily-torn sealing film is arranged at the communication position of the hollow tube (4.3) and the outside and on the upper end face of the first tube body; the hollow pipe is characterized in that one end, close to the inner bottom surface of the first pipe body (1), of the hollow pipe (4.3) is communicated with the first pipe body (1), the inner diameter of the hollow pipe (4.3) is sequentially reduced from top to bottom, the rubber sheet (4.2) is further arranged at one end, close to the inner bottom surface of the first pipe body (1), of the hollow pipe (4.3), and the periphery of the rubber sheet (4.2) is embedded on the cylinder body (4.1).

4. A disposable virus sampling tube according to claim 3, characterized in that one end of the cylinder body (4.1) close to the inner bottom surface of the first tube body (1) is horizontally provided with an annular groove (4.4), the rubber sheet (4.2) is embedded in the annular groove (4.4), and the diameter D of the rubber sheet (4.2) is larger than the outer diameter D of the annular groove (4.4).

5. A disposable virus sampling tube according to claim 3, characterized in that the rubber sheet (4.2) has a thickness of 2 mm.

6. The disposable virus sampling tube according to claim 3, wherein the rubber sheet (4.2) has a cross-shaped fracture (4.2a) in the center, and the cross-shaped fracture (4.2a) penetrates or does not penetrate the inner surface of the rubber sheet (4.2) which is in contact with the preservation solution (5).

7. The disposable virus sampling tube according to claim 1 or 2, wherein a sealing ring (3.1) is arranged on the top of the inner side of the cap (3), the sealing ring (3.1) is used for sealing the joint surface of the inner side of the cap (3) and the upper top surface of the second tube body (2), and the sealing ring (3.1) is made of silica gel.

8. A disposable virus sampling tube according to claim 1 or 2, characterized in that the inner wall of the cap (3) is provided with an annular projection (3.2) for increasing the friction between the outer wall of the upper end of the second tube body (2) and the cap (3).

9. The disposable viral sampling tube according to claim 1 or 2, further comprising a swab (8) for sampling, the stem portion of said swab (8) being provided with at least one segment of a broken stem (8.1) near the head end of the swab, the material of said stem portion being polypropylene comprising nylon fibers.

10. The disposable virus sampling tube of claim 9, wherein the material of the swab head is rayon.