CN212414246U - Biological safety monkey negative pressure isolating device - Google Patents

Abstract

The utility model discloses a biological safety type monkey negative pressure isolating device, including keeping apart box, filtration unit, power ventilation unit and the control unit, keep apart the box and set up the chamber door, the chamber door links to each other with keeping apart the box is articulated, keeps apart and sets up a plurality of in the box and keeps apart cage utensil, and the chamber door is close to one side of keeping apart cage utensil and sets up the level and smooth door, and level and smooth door slidable ground links to each other with keeping apart the box, and cage utensil bottom sets up the excrement and urine tray, and the excrement and urine tray is linked together with the inner chamber of keeping apart cage utensil, and the bottom of level. The biological safety monkey negative pressure isolation device of the utility model ensures that the isolation box body is in a negative pressure state, when the box door and the sliding door are opened, the directional flow of air can be effectively ensured, and the leakage of harmful gas in the isolation box body is avoided; simultaneously, when the transmission experimental animals excrement and urine, excrement and urine tray directly gets into in the sealed bag, carries out disinfection and isolation after sealing the sealed bag, prevents effectively that high concentration harmful organism aerosol in the excrement and urine tray from leaking the environment outside the isolator.

Description

Biological safety monkey negative pressure isolating device

Technical Field

The utility model relates to a biological safety protection equipment and peripheral supporting facility technical field especially relate to a biological safety type monkey negative pressure isolating device.

Background

In recent years, new outbreaks and outbreaks of epidemic outbreaks are continuously occurred in the global range, and serious threats are brought to the health and social stability of human beings. The experimental animal is an indispensable experimental material in life science research, plays an important role in the human pathogenic microorganism resisting course, and is particularly non-human primate.

Due to the nature of non-human primates, it is difficult to breed in a fully enclosed isolator; meanwhile, the non-human primate is vigorous, smart and aggressive, so that the infection and leakage risk is higher when the non-human primate infects epidemic experimental activities are carried out, and once the non-human primate is controlled or operated improperly, serious safety risk can be caused, and the safety of laboratory personnel and the surrounding environment is seriously threatened. Therefore, there is a need for developing a monkey negative pressure isolator which is convenient to operate and has high biological safety.

At present, monkey isolators mainly produced and used in China are mainly used for raising non-infected animals, and partial products are properly modified for carrying out pathogenic microorganism operation, but still can not completely meet the biological safety requirements for carrying out operations such as infection of highly pathogenic microorganisms of experimental animals of non-human primates, raising and the like. Since non-human primates are mainly raised in semi-open isolation cages, the need for the isolators to effectively control the exposure of pathogenic microorganisms to the external environment through airflow control, physical isolation and the like during normal operation is required.

Although monkey negative pressure isolators developed abroad can meet the requirements of biological safety to a certain extent, in some operation processes, the exposure of harmful aerosol is difficult to control, for example, in the process of feces transmission, the exposure of high-concentration pathogenic microorganisms in feces to the environment is difficult to effectively avoid.

Therefore, how to change the current situation that the isolation device cannot control the exposure of pathogenic microorganisms in the environment in the prior art becomes a problem to be solved urgently by those skilled in the art.

SUMMERY OF THE UTILITY MODEL

The utility model aims at providing a biological safety type monkey negative pressure isolating device to solve the problem that above-mentioned prior art exists, effective control pathogenic microorganism exposes in the environment, improves isolating device's biosafety.

In order to achieve the above object, the utility model provides a following scheme: the utility model provides a biological safety monkey negative pressure isolation device, which comprises an isolation box body, an air filtering unit, a power ventilation unit and a control unit, wherein the isolation box body is provided with a box door, the box door is hinged with the isolation box body, a plurality of isolation cages are arranged in the isolation box body, the number of the isolation cages is consistent with that of the box door and corresponds to that of the box door one by one, an inner cavity of the isolation cage is communicated with that of the isolation box body, the isolation cage can contain experimental animals, one side of the box door close to the isolation cage is provided with a smooth door, the smooth door is positioned between the box door and the isolation cage, the smooth door is slidably connected with the isolation box body, the bottom of the cage is provided with an excrement tray, the excrement tray is communicated with the inner cavity of the isolation cage, the bottom of the smooth door is connected with a sealing bag, the sealing bag is detachably connected with the smooth door, when the sealing bag is connected with the smooth door, a sealing element is arranged at the joint of the sealing bag and the smooth door, when the smooth door is closed, the sealing bag is arranged right opposite to the excrement tray, and the excrement tray can enter the sealing bag; the isolation box body is communicated with the external environment through the power ventilation unit, the air filtering unit is arranged between the power ventilation unit and the isolation box body, the air filtering unit can efficiently filter air flow, and the air filtering unit and the power ventilation unit are connected with the control unit.

Preferably, one side of the isolation cage close to the smooth door is provided with a fixed baffle and a grid baffle, the grid baffle is arranged at the top of the fixed baffle, the fixed baffle is provided with an animal inlet and an animal outlet, and the excrement tray is arranged at the bottom of the animal inlet and the animal outlet; the box door and the smooth door are made of transparent materials, the smooth door comprises a first sliding door and a second sliding door which are arranged in parallel, the first sliding door can block the entrance and the exit of the animal, the distance between the first sliding door and the isolation cage is larger than the distance between the second sliding door and the isolation cage, and the sealing bag is detachably connected with the first sliding door.

Preferably, a connecting flange is arranged at the bottom of the first sliding door, the connecting flange can accommodate the excrement tray, the sealing bag can be sleeved outside the connecting flange, a sealing groove is formed in the outer side wall of the connecting flange, the sealing bag is sleeved outside the connecting flange, a sealing ring is sleeved outside the sealing bag and located in the sealing groove, and the sealing bag is made of flexible materials.

Preferably, an internal baffle and a pull rod are arranged in the isolation cage, the internal baffle is connected with the isolation cage in a sliding manner, the internal baffle is arranged in parallel with the fixed baffle, the internal baffle is connected with the pull rod, the pull rod is connected with the fixed baffle in a sliding manner, the pull rod is provided with a plurality of clamping grooves, and the pull rod can be connected with the fixed baffle in a clamping manner by utilizing the clamping grooves; the grid baffle is provided with a water fountain, and the fixed baffle is provided with a feeder.

Preferably, the power ventilation unit includes air supply system and exhaust system, air supply system includes forced draught blower and supply-air duct, the forced draught blower with supply-air duct is linked together, supply-air duct set up in the chamber door with between the smooth door, the last air supply jet hole that sets up of supply-air duct, set up the fresh air inlet on the smooth door, exhaust system includes exhaust fan and exhaust duct, the exhaust fan with exhaust duct links to each other, the exhaust fan with the inner chamber of keeping apart the box is linked together, exhaust duct is linked together with external environment, keep apart the cage utensil with set up the exhaust hole on the relative lateral wall of smooth door.

Preferably, the number of the isolation cages is two, the air supply pipeline is arranged between the two isolation cages, the two isolation cages are symmetrically arranged by taking the axis of the air supply pipeline as a central line, the air supply jet holes are symmetrically arranged towards the isolation cages, the air inlet hole is arranged at one end, away from the air supply pipeline, of the smooth door, each isolation cage is arranged in a stacked mode from top to bottom, and the diameter of the air supply jet holes is gradually increased along the air supply direction of the air supply pipeline; the exhaust holes are arranged in a rectangular array, the air inlet holes are two rows, and the air inlet holes are arranged in a staggered mode.

Preferably, the air inlet fan the exhaust fan all set up in keep apart the top of box, the filtration unit includes air supply high efficiency filter, heating module, the primary filter of airing exhaust, static pressure case and the high efficiency filter of airing exhaust, air supply high efficiency filter with the heating module all with the forced draught blower links to each other, static pressure case with the primary filter of airing exhaust set up in exhaust hole department, the high efficiency filter of airing exhaust set up in the primary filter of airing exhaust with between the exhaust fan.

Preferably, the air supply efficient filter and the air exhaust efficient filter are both provided with air disinfection interfaces, the air disinfection interfaces can be connected with a disinfection machine, and the air disinfection interfaces are provided with a sealing valve and a sealing cover; and the air outlets of the air supply high-efficiency filter and the air exhaust high-efficiency filter are provided with aerosol sampling ports.

Preferably, a sensor is arranged at the door and can detect the opening and closing conditions of the door, and the sensor, the blower and the exhaust fan are all connected with the control unit.

The utility model discloses for prior art gain following technological effect: the utility model discloses a biological safety monkey negative pressure isolation device, which comprises an isolation box body, an air filtering unit, a power ventilation unit and a control unit, wherein the isolation box body is provided with a box door, the box door is hinged with the isolation box body, a plurality of isolation cages are arranged in the isolation box body, the number of the isolation cages is consistent with that of the box door and corresponds to one, the inner cavity of the isolation cages is communicated with the inner cavity of the isolation box body, the isolation cages can contain experimental animals, one side of the box door close to the isolation cages is provided with a smooth door, the smooth door is positioned between the box door and the isolation cages, the smooth door is connected with the isolation box body in a sliding way, the bottom of the cage is provided with an excrement tray, the excrement tray is communicated with the inner cavity of the isolation cages, the bottom of the smooth door is connected with a sealing bag, the sealing bag is detachably connected with the smooth door, when the sealing bag, when the smooth door is closed, the sealing bag is arranged opposite to the excrement tray, and the excrement tray can enter the sealing bag; keep apart the box and be linked together through power ventilation unit and external environment, the air filtering unit sets up between power ventilation unit and isolation box, and the air filtering unit can carry out the high efficiency to the air current and filter, and air filtering unit, power ventilation unit all link to each other with the control unit. When the biological safety monkey negative pressure isolation device works, the isolation box body is in a negative pressure state through the control unit and the power ventilation unit, and when the box door and the sliding door are opened, the directional flow of air can be effectively ensured, and the leakage of harmful gas in the isolation box body is avoided; meanwhile, the bottom of the isolation cage is provided with the excrement tray, the sealing bag is arranged outside the excrement tray, when the excrement tray needs to be taken out, the excrement tray directly enters the sealing bag, and the sealing bag is sterilized after being sealed, so that high-concentration harmful organism aerosol in the excrement tray is effectively prevented from leaking to the environment outside the isolator; in addition, the power ventilation unit is connected with the air filtering unit, can carry out high-efficient filtration to the gas that gets into and discharge the isolation box, realizes the purpose of control air inlet, the quality of airing exhaust, improves isolating device's maneuverability, avoids harmful air to discharge and causes environmental pollution to the isolation box outside, improves experimenter operational safety.

Drawings

In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required to be used in the embodiments will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to these drawings without inventive labor.

Fig. 1 is a schematic structural view of the biosafety monkey negative pressure isolation device of the present invention;

fig. 2 is a schematic structural view of another embodiment of the biosafety monkey negative pressure isolation device of the present invention;

fig. 3 is a schematic top view of the biosafety monkey negative pressure isolation device of the present invention;

fig. 4 is an enlarged schematic view of a part of the structure of the biosafety monkey negative pressure isolation device of the present invention;

fig. 5 is a schematic structural view of an isolation cage of the biosafety monkey negative pressure isolation device of the present invention;

fig. 6 is a schematic front view of the isolation cage of the biosafety monkey negative pressure isolation device of the present invention;

fig. 7 is a schematic sectional structure view of the isolation cage of the biosafety type monkey negative pressure isolation device of the present invention;

the isolation box comprises an isolation box body 1, a box door 2, an isolation cage 3, a movable baffle 301, a pull rod 302, a smooth door 4, a first sliding door 401, a second sliding door 402, a sealing bag 5, a connecting flange 6, a blower 7, an air supply pipeline 8, an air inlet hole 9, an exhaust fan 10, an exhaust pipeline 11, an exhaust hole 12, an air supply high-efficiency filter 13, an air exhaust high-efficiency filter 14 and a sealing ring 15.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.

The utility model aims at providing a biological safety type monkey negative pressure isolating device to solve the problem that above-mentioned prior art exists, effective control pathogenic microorganism exposes in the environment, improves isolating device's biosafety.

In order to make the above objects, features and advantages of the present invention more comprehensible, the present invention is described in detail with reference to the accompanying drawings and the detailed description.

Please refer to fig. 1-7, wherein, fig. 1 is the utility model discloses a biological safe type monkey negative pressure isolating device's schematic structure view, fig. 2 is the utility model discloses a biological safe type monkey negative pressure isolating device's another embodiment's schematic structure view, fig. 3 is the utility model discloses a biological safe type monkey negative pressure isolating device's overlook schematic structure view, fig. 4 is the utility model discloses a biological safe type monkey negative pressure isolating device's partial structure enlargies the schematic diagram, fig. 5 is the utility model discloses a biological safe type monkey negative pressure isolating device's structural schematic of isolation cage utensil, fig. 6 is the utility model discloses a biological safe type monkey negative pressure isolating device's isolation cage utensil's front view structural schematic, fig. 7 is the utility model discloses a biological safe type monkey negative pressure isolating device's isolation cage utensil dissects structural schematic.

The utility model provides a biological safety monkey negative pressure isolation device, which comprises an isolation box body 1, an air filtering unit, a power ventilation unit and a control unit, wherein the isolation box body 1 is provided with a box door 2, the box door 2 is hinged with the isolation box body 1, a plurality of isolation cages 3 are arranged in the isolation box body 1, the number of the isolation cages 3 is consistent with that of the box doors 2 and corresponds to one another, the inner cavity of the isolation cages 3 is communicated with the inner cavity of the isolation box body 1, the isolation cages 3 can contain experimental animals, one side of the box door 2 close to the isolation cages 3 is provided with a smooth door 4, the smooth door 4 is positioned between the box door 2 and the isolation cages 3, the smooth door 4 is slidably connected with the isolation box body 1, the bottom of the cages is provided with an excrement tray which is communicated with the inner cavity of the isolation cages 3, the bottom of the smooth door 4 is connected with a sealing bag 5, the sealing bag 5 is detachably connected with, when the sealing bag 5 is connected with the smooth door 4, a sealing element is arranged at the joint of the sealing bag 5 and the smooth door 4, when the smooth door 4 is closed, the sealing bag 5 is arranged right opposite to the excrement tray, and the excrement tray can enter the sealing bag 5; keep apart box 1 and be linked together through power ventilation unit and external environment, the air filter unit sets up between power ventilation unit and isolation box 1, and the air filter unit can carry out high efficiency filter to the air current, and air filter unit, power ventilation unit all link to each other with the control unit.

The utility model discloses a biological safe type monkey negative pressure isolating device sets up isolation cage utensil 3 in the shielded box, and isolation cage utensil 3 sets up solitary smooth door 4, sets up chamber door 2 and smooth door 4 simultaneously, makes isolating device possess good mechanical isolation nature, and cage utensil 3 is kept apart to a plurality of can separately raise, manage experimental animals. When the isolation device works, the interior of the isolation box body 1 is in a negative pressure state through the control unit and the power ventilation unit, and when the box door 2 and the sliding door 4 are opened, the directional flow of air can be effectively ensured, and the leakage of harmful gas in the isolation box body 1 is avoided; meanwhile, the bottom of the isolation cage 3 is provided with the excrement tray, the sealing bag 5 is arranged outside the excrement tray, when the excrement tray needs to be taken out, the excrement tray is directly arranged in the sealing bag 5, and the sealing bag 5 is sterilized after being sealed, so that high-concentration harmful organism aerosol in the excrement tray is effectively prevented from leaking to the environment outside the isolator; in addition, the power ventilation unit is connected with the air filtering unit, can filter the gas that gets into and discharge isolation box 1, realizes the purpose of control air inlet, the quality of airing exhaust, improves isolating device's maneuverability, and avoids harmful air to discharge and causes environmental pollution to isolation box 1 outside, improves experimenter operational safety.

Wherein, one side of the isolation cage 3 close to the smooth door 4 is provided with a fixed baffle and a grid baffle, the grid baffle is arranged at the top of the fixed baffle, the fixed baffle is provided with an animal inlet and an animal outlet, and the excrement tray is arranged at the bottom of the animal inlet and the animal outlet, so that the excrement of the experimental animal can be conveniently collected; chamber door 2 and sliding door 4 are made by transparent material, conveniently observe the experimental animal, sliding door 4 includes parallel arrangement's first push-and-pull door 401 and second push-and-pull door 402, first push-and-pull door 401 can the shutoff animal import and export, first push-and-pull door 401, keep apart the distance between cage utensil 3 than second push-and-pull door 402, keep apart the distance between cage utensil 3 big, first push-and-pull door 401 is in the one side that is close to chamber door 2 promptly, conveniently connect sealed bag 5, sealed bag 5 and first push-and-pull door 401 detachable connections.

In the embodiment, the bottom of the first sliding door 401 is provided with a connecting flange 6, the connecting flange 6 can accommodate the excrement tray to pass through, the sealing bag 5 can be sleeved outside the connecting flange 6, the outer side wall of the connecting flange 6 is provided with a sealing groove, when the sealing bag 5 is sleeved outside the connecting flange 6, the sealing bag 5 is sleeved with a sealing ring 15, the sealing ring 15 is positioned in the sealing groove, the sealing ring 15 tightly presses the sealing bag 5 on the connecting flange 6 to prevent harmful gas from leaking out from a gap between the sealing bag 5 and the connecting flange 6, the sealing bag 5 is made of flexible materials and is conveniently folded and placed between the box door 2 and the first sliding door 401, the sealing bag 5 can be made of plastic materials and can be sealed and folded, when the excrement of the experimental animal is transferred, the excrement tray is pulled into the sealing bag 5, the sealing is carried out by a heat sealing machine, and the excrement tray are put into an autoclave together for disinfection and sterilization.

In order to facilitate injecting the experimental animal, operations such as bloodletting, set up inside baffle 301 and pull rod 302 in keeping apart cage utensil 3, inside baffle 301 slidable links to each other with keeping apart cage utensil 3, inside baffle 301 and fixed stop parallel arrangement, the experimental animal is located between fixed stop and the inside baffle 301, inside baffle 301 links to each other with pull rod 302, pull rod 302 slidable links to each other with fixed stop, a plurality of draw-in grooves have on the pull rod 302, pull rod 302 can utilize the draw-in groove to link to each other with the fixed stop joint, utilize draw-in groove and the fixed stop joint of difference on the pull rod 302 to adjust the relative position between the two, improve inside baffle 301's stability simultaneously. When the experimental animal needs to be operated, the pull rod 302 is pulled, the inner baffle 301 slides towards the fixed baffle, the moving space of the experimental animal is compressed, the experimental animal is forced to move towards the direction of the fixed baffle to be close to an operator, and the experimental tool can pass through the grid baffle to complete the operations of injection, blood sampling and the like of the experimental animal; in addition, be provided with the drinking bowl on the net baffle, be provided with the feeder on the fixed stop, drinking bowl and feeder all can be dismantled, convenient cleanness, feed and eat.

In practical operation, the sum of the widths of the first sliding door 401 and the second sliding door 402 is larger than the width of the isolation cage 3, that is, the first sliding door 401 and the second sliding door 402 have overlapping parts, so that the mechanical isolation of the isolation cage 3 is further improved.

Specifically, the power ventilation unit includes air supply system and exhaust system, and air supply system includes forced draught blower 7 and supply-air duct 8, and forced draught blower 7 is linked together with supply-air duct 8, and supply-air duct 8 sets up between chamber door 2 and level and smooth door 4, sets up the air supply jet hole on the supply-air duct 8, sets up fresh air inlet 9 on the level and smooth door 4, and through filterable clean air entering supply-air duct 8, get into isolation box 1 in via the air supply jet hole, get into in each isolation cage utensil 3 through fresh air inlet 9. Exhaust system includes exhaust fan 10 and exhaust duct 11, and exhaust fan 10 links to each other with exhaust duct 11, and exhaust fan 10 is linked together with the inner chamber of keeping apart box 1, and exhaust duct 11 is linked together with external environment, keeps apart and sets up exhaust hole 12 on cage 3 and the relative lateral wall of smooth door 4, keeps apart in cage 3 air by exhaust hole 12 get into keep apart in the box 1, through exhaust fan 10 and exhaust duct 11, discharge outdoor after the filtration.

In this embodiment, the number of isolation cages 3 is two, the air supply duct 8 is disposed between the two isolation cages 3, the two isolation cages 3 are symmetrically disposed about the axis of the air supply duct 8, the air supply jet holes are symmetrically disposed toward the isolation cages 3, and the air inlet hole 9 is disposed at one end of the sliding door 4 away from the air supply duct 8. Every group keeps apart cage utensil 3 from top to bottom the stack and arranges, and 8 vertical settings of supply air duct receive the long influence of 8 small length in cross-section of supply air duct, and the air supply that easily leads to isolation cage utensil 3 from top to bottom is inhomogeneous, and then leads to the pressure differential of each isolation cage utensil 3 great difference to appear, consequently, along the air supply direction of supply air duct 8, the diameter grow gradually of air supply jet hole satisfies the air supply volume demand that is located the isolation cage utensil 3 in the air supply duct 8 low reaches. Exhaust holes 12 are arranged on the back plate of the isolation cage 3, and the exhaust holes 12 are arranged in a rectangular array shape, so that the exhaust uniformity is improved. The air inlet holes 9 are two lines, and the two lines of air inlet holes 9 are arranged in a staggered mode, so that the air inlet uniformity is improved.

More specifically, the air inlet machine, exhaust fan 10 all sets up in the top of keeping apart box 1, the filtration unit includes air supply high efficiency filter 13, the heating module, the primary filter that airs exhaust, static pressure case and the high efficiency filter 14 of airing exhaust, air supply high efficiency filter 13 and heating module all link to each other with forced draught blower 7, the heating module can heat for the air that gets into isolation box 1, static pressure case and the primary filter that airs exhaust set up in exhaust hole 12 department, the high efficiency filter 14 that airs exhaust sets up between primary filter and the exhaust fan 10, the process of airing exhaust airs exhaust is filtered through the primary filter that airs exhaust, arrange to the high efficiency filter 14 that airs exhaust through the static pressure case, through exhaust fan 10, exhaust duct 11 back row is outside isolation. It should be emphasized here that, in order to facilitate the control of the pressure in the isolation box 1, a pressure control scheme of constant delivery and variable discharge is adopted, the blower 7 and the exhaust fan 10 are both variable frequency fans, the air delivery is controlled by constant air volume, the exhaust is controlled by variable air volume, and the fan frequency is changed. The negative pressure setting value in the isolation box body 1 is-25 Pa, the negative pressure difference can be ensured to be not lower than-20 Pa under the normal operation condition of the isolation device, and meanwhile, under the condition that the box door 2 is opened and loses pressure, the exhaust fan 10 can rapidly increase the exhaust volume so as to ensure that the airflow at the box door 2 of the isolation box body 1 flows inwards all the time and effectively avoid harmful gas from leaking.

Further, air supply high efficiency filter 13 and air exhaust high efficiency filter 14 all set up gaseous disinfection interface, gaseous disinfection interface can link to each other with the sterilizing machine, gaseous disinfection interface department is provided with airtight valve and airtight lid, the disinfection gas of sterilizing machine can pierce through air supply high efficiency filter 13, send to isolation cage utensil 3 in through blast pipe 8, then pierce through air exhaust primary filter and air exhaust high efficiency filter 14, the reciprocating cycle is until the disinfection is over, it needs to explain that, air supply system and exhaust system all set up the seal valve, be convenient for control. Air outlet of air supply high efficiency filter 13 and air exhaust high efficiency filter 14 all sets up the aerosol sample connection, is convenient for adopt efficiency method leak hunting, specifically as follows, air supply high efficiency filter 13 leak hunting: generating aerosol in the room where the isolating device is located, detecting the concentration of the aerosol at the inlet of the blower 7 at the upstream of the air supply efficient filter 13 after the aerosol is stabilized, sampling at the sampling point of the aerosol at the downstream of the air supply efficient filter 13, calculating the filtering efficiency of the air supply efficient filter 13, and judging whether the air supply efficient filter 13 is intact and whether the air supply efficient filter is installed in place. And (3) leak detection of the high-efficiency exhaust filter 14: aerosol is generated in the isolation cage 3, after the aerosol is stabilized, the concentration of the aerosol at the upstream sampling point of the exhaust efficient filter 14 is detected, then the sampling is carried out at the downstream sampling point of the exhaust efficient filter 14, the filtering efficiency of the exhaust efficient filter 14 is calculated, and whether the exhaust efficient filter 14 is intact and whether the installation is in place is judged.

Furthermore, under the condition that the box door 2 is closed, clean air of the air supply system can form a protective airflow barrier between the box door 2 and the sliding door 4, in order to avoid that under the condition that the box door 2 and the sliding door 4 are both opened, jet air of the air supply jet hole sucks air in the isolation device out of the isolation device, a sensor is arranged at the box door 2 and can detect the opening and closing condition of the box door 2, when the sensor senses that the box door 2 is opened, the control unit controls the air supply machine 7 to be closed to stop air supply, and the probability of outward diffusion of the air in the isolation device is reduced. The sensor, the blower 7 and the exhaust fan 10 are all connected with the control unit, in addition, the isolation device is also provided with pressure and temperature monitoring elements, and the pressure and temperature monitoring elements are all connected with the control unit, so that an operator can monitor the state of the isolation device conveniently.

When the biological safety monkey negative pressure isolation device works, the isolation box body 1 is in a negative pressure state through the control unit and the power ventilation unit, and when the box door 2 and the sliding door 4 are opened, the directional flow of air can be effectively ensured, and harmful gas in the isolation box body 1 is prevented from leaking; meanwhile, the bottom of the isolation cage 3 is provided with the excrement tray, the sealing bag 5 is arranged outside the excrement tray, when the excrement tray needs to be taken out, the excrement tray is directly arranged in the sealing bag 5, and the sealing bag 5 is sterilized after being sealed, so that high-concentration harmful organism aerosol in the excrement tray is effectively prevented from leaking to the environment outside the isolator; in addition, the power ventilation unit is connected with the air filtering unit, can filter the gas that gets into and discharge isolation box 1, realizes the purpose of control air inlet, the quality of airing exhaust, improves isolating device's maneuverability, avoids harmful air to discharge and causes environmental pollution to isolation box 1 outside, improves experimenter operational safety. The isolating device is also provided with a gas disinfection interface, so that the whole disinfection of the device can be realized.

The utility model discloses a concrete example is applied to explain the principle and the implementation mode of the utility model, and the explanation of the above example is only used to help understand the method and the core idea of the utility model; meanwhile, for the general technical personnel in the field, according to the idea of the present invention, there are changes in the concrete implementation and the application scope. In summary, the content of the present specification should not be construed as a limitation of the present invention.

Claims (9)

1. The utility model provides a biological safety type monkey negative pressure isolating device which characterized in that: the isolation box body is provided with a box door, the box door is hinged with the isolation box body, a plurality of isolation cages are arranged in the isolation box body, the number of the isolation cages is consistent with that of the box door and corresponds to that of the box door one by one, an inner cavity of each isolation cage is communicated with an inner cavity of the isolation box body, each isolation cage can contain experimental animals, a smooth door is arranged on one side, close to the isolation cage, of the box door and is positioned between the box door and the isolation cages, the smooth door is slidably connected with the isolation box body, an excrement tray is arranged at the bottom of each cage and is communicated with the inner cavity of each isolation cage, a sealing bag is connected to the bottom of the smooth door and is detachably connected with the smooth door, when the sealing bag is connected with the smooth door, a sealing element is arranged at the joint of the sealing bag and the smooth door, when the smooth door is closed, the sealing bag is arranged right opposite to the excrement tray, and the excrement tray can enter the sealing bag; the isolation box body is communicated with the external environment through the power ventilation unit, the air filtering unit is arranged between the power ventilation unit and the isolation box body, the air filtering unit can efficiently filter air flow, and the air filtering unit and the power ventilation unit are connected with the control unit.

2. The biosafety monkey negative pressure isolation device of claim 1, wherein: a fixed baffle and a grid baffle are arranged on one side of the isolation cage close to the smooth door, the grid baffle is arranged at the top of the fixed baffle, an animal inlet and an animal outlet are formed in the fixed baffle, and the excrement tray is arranged at the bottom of the animal inlet and the animal outlet; the box door and the smooth door are made of transparent materials, the smooth door comprises a first sliding door and a second sliding door which are arranged in parallel, the first sliding door can block the entrance and the exit of the animal, the distance between the first sliding door and the isolation cage is larger than the distance between the second sliding door and the isolation cage, and the sealing bag is detachably connected with the first sliding door.

3. The biosafety monkey negative pressure isolation device of claim 2, wherein: the excrement tray is arranged on the bottom of the first sliding door, the connecting flange can accommodate the excrement tray, the sealing bag can be sleeved outside the connecting flange, the outer side wall of the connecting flange is provided with a sealing groove, the sealing bag is sleeved outside the connecting flange, a sealing ring is sleeved outside the sealing bag and located in the sealing groove, and the sealing bag is made of flexible materials.

4. The biosafety monkey negative pressure isolation device of claim 2, wherein: an internal baffle and a pull rod are arranged in the isolation cage, the internal baffle is connected with the isolation cage in a sliding manner, the internal baffle is arranged in parallel with the fixed baffle, the internal baffle is connected with the pull rod, the pull rod is connected with the fixed baffle in a sliding manner, the pull rod is provided with a plurality of clamping grooves, and the pull rod can be connected with the fixed baffle in a clamping manner by utilizing the clamping grooves; the grid baffle is provided with a water fountain, and the fixed baffle is provided with a feeder.

5. The biosafety monkey negative pressure isolation device of claim 1, wherein: the power ventilation unit comprises an air supply system and an exhaust system, the air supply system comprises an air supply machine and an air supply pipeline, the air supply machine is communicated with the air supply pipeline, the air supply pipeline is arranged between the box door and the smooth door, an air supply jet hole is formed in the air supply pipeline, an air inlet hole is formed in the smooth door, the exhaust system comprises an exhaust fan and an exhaust pipeline, the exhaust fan is connected with the exhaust pipeline, the exhaust fan is communicated with the inner cavity of the isolation box body, the exhaust pipeline is communicated with the external environment, and the isolation cage is provided with an exhaust hole on the side wall opposite to the smooth door.

6. The biosafety monkey negative pressure isolation device of claim 5, wherein: the number of the isolation cages is two, the air supply pipeline is arranged between the two isolation cages, the two isolation cages are symmetrically arranged by taking the axis of the air supply pipeline as a central line, the air supply jet holes are symmetrically arranged towards the isolation cages, the air inlet holes are arranged at one end, away from the air supply pipeline, of the smooth door, and each isolation cage is overlapped and distributed from top to bottom; a plurality of the air exhaust holes are arranged in a rectangular array.

7. The biosafety monkey negative pressure isolation device of claim 6, wherein: the air feeder and the exhaust fan are arranged at the top of the isolation box body, the air filtering unit comprises an air feeding high-efficiency filter, a heating module, an air exhaust primary-effect filter, a static pressure box and an air exhaust high-efficiency filter, the air feeding high-efficiency filter and the heating module are connected with the air feeder, the static pressure box and the air exhaust primary-effect filter are arranged at the position of the air exhaust hole, and the air exhaust high-efficiency filter is arranged between the air exhaust primary-effect filter and the exhaust fan.

8. The biosafety monkey negative pressure isolation device of claim 7, wherein: the air supply efficient filter and the air exhaust efficient filter are both provided with air disinfection interfaces, the air disinfection interfaces can be connected with a disinfection machine, and the air disinfection interfaces are provided with a sealing valve and a sealing cover; and the air outlets of the air supply high-efficiency filter and the air exhaust high-efficiency filter are provided with aerosol sampling ports.

9. The biosafety monkey negative pressure isolation device of claim 8, wherein: the door department sets up the sensor, the sensor can detect the switching condition of door, the sensor the forced draught blower, the exhaust fan all with the control unit links to each other.

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