CN207678573U - Isolating device - Google Patents

Isolating device Download PDF

Info

Publication number
CN207678573U
CN207678573U CN201721450999.5U CN201721450999U CN207678573U CN 207678573 U CN207678573 U CN 207678573U CN 201721450999 U CN201721450999 U CN 201721450999U CN 207678573 U CN207678573 U CN 207678573U
Authority
CN
China
Prior art keywords
cofferdam
auxiliary member
lid
affixed
filter
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201721450999.5U
Other languages
Chinese (zh)
Inventor
刘婕
王晓雷
商海涛
王聪
蒋吉鹏
于目标
魏泓
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wuhan Hualianke Biotechnology Co ltd
Original Assignee
Qianhai Shenzhen Jin Zhuo Biotechnology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Qianhai Shenzhen Jin Zhuo Biotechnology Co Ltd filed Critical Qianhai Shenzhen Jin Zhuo Biotechnology Co Ltd
Priority to CN201721450999.5U priority Critical patent/CN207678573U/en
Application granted granted Critical
Publication of CN207678573U publication Critical patent/CN207678573U/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Landscapes

  • Accommodation For Nursing Or Treatment Tables (AREA)

Abstract

The utility model is related to a kind of isolating devices.The isolating device includes interrupter and ventilating mechanisms;Interrupter includes barrier assembly and transmitting assembly, barrier assembly and transmitting assembly are at least two, barrier assembly includes cofferdam, operating gloves and auxiliary member, cofferdam is equipped with installing port, operating gloves are with auxiliary member interval and are tightly connected with cofferdam, transmitting assembly includes being arranged in installing port and the transferring cabin being tightly connected with cofferdam and the first lid for being contained in cofferdam, auxiliary member and operating gloves can cooperate, so that the first cover cap is set to transferring cabin;Ventilating mechanisms include air-supply assembly, air-supply assembly includes pneumatic actuator, ajutage and filter, ajutage and filter are at least two, one end of at least two ajutages is affixed with pneumatic actuator, the other end is affixed at least two filters respectively, and at least two filters are tightly connected at least two cofferdams respectively.Above-mentioned isolating device can keep gnotobasis for a long time.

Description

Isolating device
Technical field
The utility model is related to sterile operating device fields, more particularly to a kind of isolating device.
Background technology
Germfree animal refers to the animal of the microorganism and parasite that cannot detect any work.With the research day to germfree animal Gradually deeply, the requirement to the breeding apparatus of germfree animal is also higher and higher.Currently, due to the construction of most of isolating device and logical Wind system has some limitations, it is caused to be unable to maintain that the germ-free condition of long period, especially during long-time service, The problem of cannot maintaining germ-free condition, is more obvious, and then these isolating devices is caused to cannot be satisfied the long-term feeding of germfree animal It supports.
Utility model content
Based on this, a kind of isolating device being able to maintain that long period germ-free condition is provided.
A kind of isolating device, including interrupter and ventilating mechanisms;
The interrupter includes barrier assembly and transmitting assembly, and the barrier assembly and the transmitting assembly are at least two A, each barrier assembly includes cofferdam, operating gloves and auxiliary member, and the cofferdam is equipped with installing port, the operation Gloves are tightly connected with the cofferdam, and the auxiliary member is arranged with the operating gloves interval, and the auxiliary member is close to institute Installing port setting is stated, the auxiliary member is tightly connected with the cofferdam, and each transmitting assembly includes transferring cabin, the first lid Body and the second lid, the transferring cabin is arranged in the installing port, and is tightly connected with the cofferdam, and first lid is received It is dissolved in the cofferdam, and is covered on the side of the transferring cabin, second cover cap is set to the transferring cabin far from institute State the side of the first lid, wherein the auxiliary member and the operating gloves can cooperate, so that first cover cap Set on the transferring cabin;
The ventilating mechanisms include air-supply assembly, and the air-supply assembly includes pneumatic actuator, ajutage and filter, institute It is at least two to state ajutage and the filter, and one end of at least two ajutages is solid with the pneumatic actuator Connect, the other end is affixed at least two filters respectively, at least two filters respectively with described at least two every It is tightly connected from cabin.
The interrupter of above-mentioned isolating device includes barrier assembly and transmitting assembly, and barrier assembly includes cofferdam and operation Gloves can carry out sterile working or cultivation germfree animal by operating gloves in cofferdam.Cofferdam is equipped with installing port, Transmitting assembly includes transferring cabin, the first lid and the second lid, and transferring cabin is arranged in installing port, and is tightly connected with cofferdam, By the way that transferring cabin is arranged, be conducive to transmit article to the inside of cofferdam and passes out the article inside cofferdam.First lid Body is contained in cofferdam, and is covered on transferring cabin, and the second cover cap is set to side of the transferring cabin far from the first lid, by setting The first lid and the second lid are set, transferring cabin can be sealed, and then is conducive to keep the germ-free condition of transferring cabin and cofferdam. Since barrier assembly further includes auxiliary member, auxiliary member is arranged with operating gloves interval, and auxiliary member is arranged close to installing port, transferring cabin It is arranged in installing port, and auxiliary member and operating gloves can cooperate, so that the first cover cap is set to transferring cabin, can passed through First lid is more tightly sealed on transferring cabin by the mutual cooperation of auxiliary member and operating gloves, is avoided the occurrence of due to first The problem of lid fails closing tightly and makes cofferdam microbiological contamination, and then ensure that the germ-free condition of cofferdam so that above-mentioned isolation Device can maintain germ-free condition the long period, and then be conducive to the Long-term breeding of germfree animal.Simultaneously as at least two send One end of air hose is affixed with pneumatic actuator, and the other end is affixed at least two filters respectively, at least two filters point It is not tightly connected at least two cofferdams so that pneumatic actuator can give at least two cofferdams to divulge information, and due to each Ajutage is tightly connected through a filter and a cofferdam, so that each cofferdam has a set of individual wind path system The problem of uniting, and then preventing from causing multiple cofferdams to pollute because of a cofferdam pollution in the long-term use, avoids Cross contamination between multiple cofferdams, further ensures the germ-free condition of cofferdam in the long-term use.Through reality Verification, above-mentioned isolating device place 12 months still in germ-free condition, cultivation germfree animal 12 months still in germ-free condition, Aseptic feed is transmitted in above-mentioned isolating device 32 times still in germ-free condition.Above-mentioned isolating device can keep sterile for a long time Environment.
The auxiliary member is that the cofferdam is recessed inwardly the groove to be formed in one of the embodiments,;Or,
The auxiliary member is soft bag.
The auxiliary member is one in one of the embodiments, and an auxiliary member is distinguished with the operating gloves It is arranged in the both sides of the installing port;Or,
The auxiliary member at least two, at least two auxiliary member interval settings, and it is separately positioned on the installation The both sides of mouth.
The cofferdam is the cabins PVC or the cabins PU in one of the embodiments,;And/or
The auxiliary member is PVC bags or PU bags;And/or
The operating gloves include glove bulk and connecting cylinder, and one end sealing of the glove bulk and the connecting cylinder connects It connects, the other end of the connecting cylinder is tightly connected with the cofferdam, and the glove bulk is butyronitrile gloves, and the connecting cylinder is PVC or PU;And/or
The transferring cabin is the cabins PC.
Second lid includes lid main body and sealing element, the lid ontology setting in one of the embodiments, Mouth is sterilized, the sealing element is inserted in the disinfection mouth.
Each filter includes shell and filter core in one of the embodiments, and the filter core is contained in the shell Body, and it is affixed with the shell, the filter core is tightly connected with the cofferdam, so that the filter core and the cofferdam phase It is logical.
The pneumatic actuator has at least two connectors, at least two air-supplies in one of the embodiments, One end of pipe is affixed at least two connectors respectively, and the other end is affixed at least two filters respectively, at least Two cofferdams are equipped with air outlet, and at least two filters are sent with described at least two cofferdams respectively Air port is tightly connected.
The air-supply assembly includes ball valve in one of the embodiments, the ball valve at least two, at least two institutes The one end for stating ball valve is affixed at least two filters respectively, and the other end is respectively at least two ajutages far from institute The one end for stating pneumatic actuator is affixed.
The air-supply assembly includes pipe collar in one of the embodiments, and the pipe valve is at least two pairs, each ball One end of valve is affixed by a pipe collar and a filter, and the other end passes through described in a pipe collar and one The one end of ajutage far from the pneumatic actuator is affixed.
The ventilating mechanisms further include air draft mechanism in one of the embodiments, air draft component setting it is described every It is tightly connected from side of the cabin far from the air-supply assembly, and with the cofferdam.
Description of the drawings
Fig. 1 is the structural schematic diagram of the isolating device of an embodiment;
Fig. 2 is the structural schematic diagram of another angle of isolating device shown in FIG. 1;
Fig. 3 is the structural schematic diagram of another angle of isolating device shown in FIG. 1;
Fig. 4 is sectional view of the filter along A-A' lines of isolating device shown in Fig. 2;
Fig. 5 is the structural schematic diagram of another angle of isolating device shown in Fig. 2.
Specific implementation mode
The utility model is more fully retouched below with reference to relevant drawings for the ease of understanding the utility model, It states.The preferred embodiment of the utility model is given in attached drawing.But the utility model can come in many different forms It realizes, however it is not limited to embodiment described herein.Make to the utility model on the contrary, purpose of providing these embodiments is The understanding of disclosure is more thorough and comprehensive.
It should be noted that when element is referred to as " being fixed on " another element, it can be directly on another element Or there may also be elements placed in the middle.When an element is considered as " connection " another element, it can be directly connected to To another element or it may be simultaneously present centering elements.Term as used herein " vertical ", " horizontal ", " left side ", " right side " and similar statement are for illustrative purposes only.
Unless otherwise defined, all of technologies and scientific terms used here by the article is led with the technology for belonging to the utility model The normally understood meaning of technical staff in domain is identical.Terminology used in the description of the utility model herein only be The purpose of description specific embodiment, it is not intended that in limitation the utility model.
As shown in Figure 1, the isolating device 10 of an embodiment includes holder 100, interrupter and ventilating mechanisms.
Holder 100 is the supporting mechanism of isolating device 10.Holder 100 includes frame body 110 and slide assemblies 120.Frame body 110 For the main body of holder 100.Frame body 110 is metal framework.Frame body 110 is that removably frame can be by frame when carrying frame body 110 Body 110 is dismantled, and is reduced the volume of frame body 110, is easily portable.In the shown embodiment, frame body 110 is stainless steel frame, and It is cube shaped.
It is appreciated that frame body 110 is not limited to detachable structure, can also integral structure, and then simplify the system of frame body 110 Make flow.It is appreciated that frame body 110 is not limited to stainless steel frame, or iron frame can also be other metal frames Frame.
Also referring to Fig. 2, frame body 110 includes column 112, erecting bed 114 and connecting rod 116.Column 112 is metal Pipe, and be vertically arranged.In the shown embodiment, column 112 is stainless steel tube.It is appreciated that column 112 is not limited to stainless steel Pipe, or iron pipe can also be other metal frameworks.Further, column 112 is multiple, and multiple columns 112 are spaced And it is vertically arranged.In the shown embodiment, column 112 is two pairs, two columns 112 interval setting, per in column 112 Two columns 112 are spaced and are arranged in parallel.
Also referring to Fig. 3, erecting bed 114 is for being arranged interrupter.Erecting bed 114 is fixedly connected with column 112, with It is in layer structure to make frame body 110.In the shown embodiment, erecting bed 114 is the square box being made of four cross bars 1142, often The both ends of a cross bar 1142 are affixed with two columns 112 respectively.Further, erecting bed 114 is multiple, multiple erecting beds 114 Interval setting, and it is affixed with column 112.In the shown embodiment, erecting bed 114 is four, and four erecting beds 114 are spaced And be arranged in parallel, and it is affixed with column 112, so that frame body 110 is in four-layer structure.
The both ends of connecting rod 116 are affixed with two neighboring column 112 respectively.In the shown embodiment, connecting rod 116 is total There are four pairs, every two pairs of connecting rods 116 are opposite and interval is arranged.Two connecting rods 116 in each pair of connecting rod 116, which are spaced, to be set It sets, and is respectively positioned between two neighboring erecting bed 114.
Slide assemblies 120 are for keeping frame body 110 free to slide and stop bit.Slide assemblies 120 are arranged at intervals on frame body 110 side, and be rotatablely connected with frame body 110.Specifically, slide assemblies 120 include connector 122 and pulley 124, connector 122 is affixed with one end of column 112, and connector 122 is flexibly connected with pulley 124, to realize the sliding of frame body 110 and stop Position.In the shown embodiment, slide assemblies 120 are four, four interval of slide assemblies 120 settings, and four slide assemblies 120 is affixed with one end of four columns 112 respectively, so that frame body 110 can either smoothly be vertically arranged and can slide and stop Position.
Interrupter is the core component of isolating device 10.Interrupter includes barrier assembly 210 and transmitting assembly 220. Barrier assembly 210 is the place for carrying out sterile working or cultivating germfree animal.Barrier assembly 210 is set to frame body 110 far from sliding The side of dynamic component 120, and it is affixed with frame body 110.Specifically, barrier assembly 210 includes cofferdam 211, detector 212, peace Shelve 213, box body 215, operating gloves 217 and auxiliary member 219.
Cofferdam 211 is the shell of barrier assembly 210.Cofferdam 211 is hollow transparency cabin, and is cube shaped. In illustrated embodiment, cofferdam 211 is transparent PVC (Polyvinyl chloride, polyvinyl chloride) cabin, by transparent PVC film is made.Since PVC film has the performances such as preferable stretch-proof, bend resistance, resistance to compression and shock resistance so that cofferdam 211 have the performances such as preferable stretch-proof, bend resistance, resistance to compression and shock resistance, can ensure the service life of cofferdam 211, and So that cofferdam 211 is able to maintain that permanent germ-free condition.
Cofferdam 211 is arranged in side of the frame body 110 far from slide assemblies 120, and affixed with frame body 110.Specifically, every It is arranged on side of the erecting bed 114 far from slide assemblies 120 from cabin 211, and between two neighboring erecting bed 114, every Side from cabin 211 offers installing port.Further, side of the cofferdam 211 far from slide assemblies 120 is provided with fixing piece 214, fixing piece 214 can be affixed with cofferdam 211, erecting bed 114, so that cofferdam 211 is solid with erecting bed 114 It connects.Fixing piece 214 is multiple, and the interval of multiple fixing pieces 214 is arranged and is uniformly distributed in cofferdam 211 far from slide assemblies 120 Side so that cofferdam 211 can be more steadily set on erecting bed 114.
In the shown embodiment, cofferdam 211 is cube shaped, and cofferdam 211 has the first mounting surface 2112, second Mounting surface 2114 and third mounting surface 2116, the first mounting surface 2112, the second mounting surface 2114 and third mounting surface 2116 are perpendicular It is straight to be arranged on erecting bed 114.First mounting surface 2112 and the second mounting surface 2114 are oppositely arranged, and third mounting surface 2116 is located at Between first 2112 grade second of mounting surface mounting surface 2114, and with the first mounting surface 2112 and the second mounting surface 2114 company of sealing It connects.Installing port is opened on the first mounting surface 2112.Further, the first mounting surface 2112 is equipped with air outlet, and air outlet is close Installing port is arranged, and is arranged with installing port interval.Second mounting surface 2114 is equipped with exhaust outlet.Further, fixing piece 214 is four A, four intervals of fixing piece 214 are arranged and are uniformly distributed in side of the cofferdam 211 far from slide assemblies 120, so that cofferdam 211 can steadily be set on erecting bed 114.
Detector 212 is used to detect the parameters such as pressure, temperature and the humidity inside cofferdam 211.Detector 212 be located at every Outside from cabin 211, and be tightly connected with cofferdam 211.In the shown embodiment, detector 212 is set to cofferdam 211 The first mounting surface 2112 on.Certainly, it should be noted that detector 212 can be that can simultaneously measure inside cofferdam 211 The parameters such as pressure, temperature and humidity component, or one in pressure inductor, temperature inductor and humidity sensor Kind.
Mounting bracket 213 is for placing box body 215.Mounting bracket 213 is layer structure, and mounting bracket 213 is contained in cofferdam In 211.Further, mounting bracket 213 has multiple objective tables 2131, the interval of multiple objective tables 2131 setting, so that mounting bracket 213 be in layer structure.
In the shown embodiment, the tool of mounting bracket 213 is there are three objective table 2131, three intervals of objective tables 2131 and parallel Setting, so that mounting bracket 213 is three-decker.Further, three objective tables 2131 are with cofferdam 211 close to slide assemblies 120 side interval setting so that three mounting brackets 213 with cofferdam 211 close to the side mutual cooperation shape of slide assemblies 120 At four-layer structure.Box body 215 is the place for carrying out sterile working or cultivating germfree animal.Box body 215 is contained in cofferdam 211 In, and be arranged in objective table 2131 and cofferdam 211 at least one of side of erecting bed 114.Box body 215 is more It is a, the setting of the interval of multiple box bodys 215, and objective table 2131 and cofferdam 211 are distributed in the side of slide assemblies 120 On at least one.In the shown embodiment, three objective tables 2131 of each cofferdam 211 and the cofferdam 211 are close to sliding It is both provided with multiple spaced box bodys 215 on the side of dynamic component 120.
Operating gloves 217 are convenient for carrying out sterile working in cofferdam 211.Operating gloves 217 connect with the sealing of cofferdam 211 It connects.In the shown embodiment, operating gloves 217 include connecting cylinder 2171 and glove bulk 2173.Connecting cylinder 2171 is hollow Tubular is PVC, is made by PVC film that one end and the cofferdam 211 of connecting cylinder 2171 are tightly connected.It is appreciated that connecting Connect cylinder 2171 is not limited to PVC, can also be PU.Glove bulk 2173 be hand-type butyronitrile gloves, glove bulk 2173 with The one end of connecting cylinder 2171 far from cofferdam 211 is tightly connected.By PVC and butyronitrile gloves make operating gloves 217 have compared with Strong mechanical performance, impact resistance and acidproof and resistance to alkali ability, can ensure the service life of operating gloves 217, and then make It obtains cofferdam 211 and is able to maintain that permanent germ-free condition.
Auxiliary member 219 is bag-shaped, and is tightly connected with cofferdam 211.Auxiliary member 219 is arranged with the interval of operating gloves 217, And auxiliary member 219 is arranged close to installing port, to allow the operator to the mutual cooperation by auxiliary member 219 and operating gloves 217 To seal transmitting assembly 220.Further, auxiliary member 219 is set on the first mounting surface 2112 of cofferdam 211, and is assisted Part 219 is formed for the first mounting surface 2112 of cofferdam 211 to being recessed close to the direction of the second mounting surface 2114 and extending Groove so that cofferdam 211 is in integral structure with auxiliary member 219, and then ensures the sealing effect of cofferdam 211.
Further, barrier assembly 210 is at least two, the setting of at least two barrier assemblies 210 interval, and be may be contained within Side of the frame body 110 far from slide assemblies 120, and it is affixed with frame body 110.Correspondingly, cofferdam 211, detector 212, installation Frame 213, operating gloves 217 and auxiliary member 219 are at least two.At least two cofferdams 211 are separately positioned on multiple installations On side of the platform 114 far from slide assemblies 120, and it is respectively positioned between two neighboring erecting bed 114.Each cofferdam 211 is logical It crosses fixing piece 214 and erecting bed 114 is affixed.
In the shown embodiment, there are two cofferdam 211 is total to, two cofferdams 211 are respectively arranged on four erecting beds 114 In centre two on.Each side of the cofferdam 211 far from slide assemblies 120 is respectively provided with there are four fixing piece 214, and four solid Determine the setting of the interval of part 214 and is uniformly distributed in side of each cofferdam 211 far from slide assemblies 120.Each cofferdam 211 is Corresponding 212, mounting brackets 213 of a detector and an auxiliary member 219.Specifically, 211 corresponding auxiliary of each cofferdam Part 219 may be contained on the first mounting surface 2112 of the cofferdam 211, and positioned at the first mounting surface 2112 far from third mounting surface 2116 side, so that the installing port of cofferdam 211 is between auxiliary member 219 and operating gloves 217.
Further, each cofferdam 211 is respectively provided with there are two the operating gloves 217 being spaced, and the of each cofferdam 211 Three mounting surfaces 2116 be all provided with there are two be spaced through-hole 2117, two operating gloves 217 respectively with third mounting surface 2116 two A through-hole 2117 is tightly connected, and then two hands of person easy to operation can put on operating gloves 217 and in cofferdam 211 Carry out sterile working.It is to be appreciated that the quantity of 211 corresponding operating gloves 217 of each cofferdam is not limited to two, it can also To be multiple, can be configured according to actual needs.When operating gloves 217 are multiple, the interval of multiple operating gloves 217 is arranged, And it is tightly connected with cofferdam 211.
Transmitting assembly 220 is used to be passed to article into barrier assembly 210 or spreads out of article from barrier assembly 210.It transmits Component 220 is tightly connected with barrier assembly 210, and affixed with frame body 110.Specifically, transmitting assembly 220 include transferring cabin 221, First lid 223 and the second lid 225.Transferring cabin 221 is hollow transparency cabin, and is tubbiness.Transferring cabin 221 is arranged in isolation The installing port in cabin 211, and be tightly connected with cofferdam 211, transferring cabin 221 is located between a pair of of connecting rod 116, and even with a pair Two connecting rods 116 in extension bar 116 are affixed.In the shown embodiment, transferring cabin 221 is transparent PC (Polycarbonate, makrolon) cabin, is made of PC materials.
First lid 223 is circular lid, and is contained in cofferdam 211, and can be covered on the side of transferring cabin 221 On, to seal the side of transferring cabin 221.Further, when the first lid 223 is covered on transferring cabin 221, auxiliary member 219 is remote Side from the first mounting surface 2112 can be abutted with the first side of the lid 223 far from transferring cabin 221, to allow the operator to First lid 223 is closely covered on transferring cabin 221 by the mutual cooperation of auxiliary member 219 and operating gloves 217 On side, avoid the occurrence of due to the first lid 223 fail closing it is tight and the problem of make 211 microbiological contamination of cofferdam, and then ensure that The germ-free condition of cofferdam 211 so that isolating device 10 can maintain germ-free condition the long period, and then be conducive to germfree animal Long-term breeding.
Certainly, it should be noted that auxiliary member 219 can also be extended from the first mounting surface 2112 to close to the second mounting surface The length that 2114 direction extends, so that when the first lid 223 is positioned over cofferdam 211 and is not covered on transferring cabin 221, Can the first lid 223 be covered on to the side of cofferdam 211 by auxiliary member 219, and pass through auxiliary member 219 and operating gloves First lid 223 is closely covered on the side of transferring cabin 221 by 217 mutual cooperation.
Second lid 225 is circular lid, and is covered on side of the transferring cabin 221 far from the first lid 223, so that sealing passes Pass side of the cabin 211 far from the first lid 223.Further, the second lid 225 includes lid main body 2250 and sealing element 2254.Lid main body 2250 is equipped with spaced disinfection mouth 2251 and exhaust outlet 2253, sterilizes mouth 2251 and exhaust outlet 2253 Run through lid main body 2250, and it is from the second lid 225 to the side of the first lid 223 to sterilize mouth 2251 and exhaust outlet 2253 To the through-hole of extension.It is fitted with sealing element 2254 in disinfection mouth 2251 and exhaust outlet 2253, and then ensures the close of transferring cabin 221 Envelope state.When article to be sterilized is positioned over the disinfection of transferring cabin 221, sprayed by sterilizing 2251 pairs of articles to be sterilized of mouth Mist sterilizes, and keeps exhaust outlet 2253 in the open state so that keeps pressure balance in transferring cabin 221, prevents the second lid 225 It falls off, influences the Disinfection Effect of article to be sterilized.
In the shown embodiment, the second lid 225 sets that there are one a disinfection mouths 2251 and exhaust outlet 2253.Sterilize mouth 2251 are opened in the center of lid main body 2250, and exhaust outlet 2253 is arranged close to disinfection mouth 2251, and exhaust outlet 2253 and disinfection 2251 interval setting of mouth.Disinfection mouth 2251 is arranged at the center of lid main body 2250, so that thimerosal can be from disinfection mouth It is uniformly sprayed on article to be sterilized in 2251.
Transmitting assembly 220 is at least two, the setting of at least two transmitting assemblies 220 interval, and affixed with frame body 110. At least two transmitting assemblies 220 are tightly connected at least two barrier assemblies 210 respectively.Correspondingly, transferring cabin 221, first covers Body 223 and the second lid 225 are at least two.
In the shown embodiment, transmitting assembly 220 altogether there are two, correspondingly, transferring cabin 211, the first lid 223 and the There are two two lids 225 are total to, and each transferring cabin 221 corresponds to first lid 223 and second lid 225.Often A transmitting assembly 220 corresponds to a barrier assembly 210, and correspondingly, each transferring cabin 221 corresponds to a cofferdam 211, two biographies Pass cabin 221 and be arranged in the installing port of two cofferdams 211 respectively, and be located between two pairs of connecting rods 116 so that one every A transferring cabin 221 is corresponded to from cabin 211.It is appreciated that the quantity of 210 corresponding transmitting assembly 220 of each barrier assembly is unlimited In one, or two, can also be three, can be configured as needed.
Ventilating mechanisms be used for filtrated air is passed through in cofferdam 211, not only ensured the germ-free condition in cofferdam 211, but also Oxygen is provided to germfree animal.Ventilating mechanisms include air-supply assembly 310 and air draft component 310', air-supply assembly 310 and air draft group Part 310' is separately positioned on the both sides of cofferdam 211, and is tightly connected with cofferdam 211.
Air-supply assembly 310 includes pneumatic actuator 311, filter 313, ajutage 315, ball valve 317 and pipe collar 319.Wind Power drive 311 is for improving air pressure and dispatch air.Pneumatic actuator 311 is fixed on frame body 110.Implement in diagram In mode, pneumatic actuator 311 is fixed on an erecting bed 114 close to slide assemblies 120, and is fixed on the erecting bed 114 Side far from slide assemblies 120.
Further, pneumatic actuator 311 has for the connector affixed with ajutage 315.Pneumatic actuator 311 Connector at least two, so that pneumatic actuator 311 can give at least two cofferdams, 211 dispatch air.Pneumatic actuator 311 are at least one.In the shown embodiment, there are one pneumatic actuator 311 is total to, a pneumatic actuator 311 has two A connector can either reinforce wind-force so that a pneumatic actuator 311 can give two 211 dispatch air of cofferdam simultaneously The service efficiency of driver 311, and the generation of noise can be reduced, meanwhile, it is capable to by be arranged two ajutages 315 respectively with Two connector connections lead to the cross contamination of two cofferdams 211 to avoid a shared ajutage 315.
Filter 313 is used to filter the air of 311 dispatch of pneumatic actuator, and then ensures to enter the sky in cofferdam 211 Gas is filtrated air.Filter 313 can be subjected to the processing that high temperature and pressure repeatedly sterilizes, and then can reduce by 211 quilt of cofferdam The cost of the risk of pollution and entire isolating device 10.Filter 313 is primary filter, medium effeciency filter and high efficiency filter Device.Preferably, filter 313 is high efficiency particulate air filter, so that isolating device 10 can reach cultivation germfree animal or progress The standard of sterile working.
Also referring to Fig. 4, filter 313 includes shell 3130, filter core 3134, sealing element 3138 and connector 3139. Shell 3130 is the shell of filter 313, and shell 3130 is hollow stainless steel cylinder, is cylindrical.Specifically, shell 3130 Including housing body 31301 and lid 31303.Housing body 31301 is the hollow circuit cylinder bodily form.Housing body 31301 has phase To opening and bottom, the bottom of housing body 31301 be welded seal, the side wall of housing body 31301 is equipped with air port 31305。
Lid 31303 is the hollow circuit cylinder bodily form, and is covered on the top of housing body 31301, with shielding casing main body 31301 opening, lid 31303 are tightly connected with housing body 31301.Side of the lid 31303 far from housing body 31301 Equipped with extension 31307, extension 31307 is tool there are two the hollow tube being open, and extension 31307 is contained in lid 31303, And one end of extension 31307 and lid 31303 are affixed.The inner surface of extension 31307 has screw thread.
Filter core 3134 is for filtering air.Filter core 3134 is PTFE (Poly tetra fluoroethylene, polytetrafluoro Ethylene) core is cylindrical.Filter core 3134 is contained in shell 3130, and affixed with shell 3130, filter core 3134 and shell 3130 Between there are gaps.In the shown embodiment, filter core 3134 includes filter core main body 31341 and connecting tube 31343, filter core main body 31341 be cylindrical, and filter core main body 31341 is contained in housing body 31301, and is existed between housing body 31301 Gap.Connecting tube 31343 is contained in lid 31303, and one end of connecting tube 31343 and filter core main body 31341 are close to lid 31303 one end is affixed, and the other end of connecting tube 31343 is inserted in extension 31307, so that connecting tube 31343, filter core master Body 31341 is communicated with extension 31307.In the shown embodiment, connecting tube 31343 far from filter core main body 31341 one There is screw thread, the one end of connecting tube 31343 far from filter core main body 31341 to be inserted in extension 31307 for the outer surface at end, and with Extension 31307 screws.
Sealing element 3138 is for making shell 3130 be tightly connected with filter core 3134.Sealing element 3138 is circular ring shape, and is clamped Between extension 31307 and filter core main body 31341.In the shown embodiment, sealing element 3138 is washer, and is clamped in and prolongs It stretches between pipe 31307 and filter core main body 31341, so that shell 3130 is tightly connected with filter core 3134.
Connector 3139 is for filter 313 to be connect with cofferdam 211.Connector 3139 is hollow tubular, connector 3139 one end is tightly connected with cofferdam 211, and the other end is tightly connected with filter core 3134, so that filter core 3134 and cofferdam 211 communicate.In the shown embodiment, one end of connector 3139 and the air outlet of the first mounting surface 2112 are tightly connected, even The other end of fitting 3139 is tightly connected with side of the extension 31307 far from filter core 3134, so that filter core 3134 and cofferdam 211 are tightly connected, and then filter core 3134 is made to be communicated with cofferdam 211.
Into one, filter 313 is at least two, and at least two filters 313 are close at least two cofferdams 211 respectively Envelope connection.In the shown embodiment, there are two filter 313 is total to, two filters 313 are close with two cofferdams 211 respectively Envelope connection can either accelerate the filter efficiency of air, in turn avoid so that a cofferdam 211 corresponds to a filter 313 Two or more cofferdams 211 share cross contamination caused by a filter 313.
Ajutage 315 is used for transport air.One end of ajutage 315 and pneumatic actuator 311 are affixed, the other end and filtering Device 313 is affixed.Further, ajutage 315 includes tube body 3151, connector 3153 and anchor ear 3155.Tube body 3151 is hollow Tubulose, and one end of tube body 3151 and the connector of pneumatic actuator 311 are affixed, the other end and connector 3153 are affixed.Connection One end of first 3153 generally hollow tubulose, connector 3153 is inserted in the one end of tube body 3151 far from pneumatic actuator 311, And fixed connector 3153 and tube body 3151 with anchor ear 3155, and then tube body 3151 is made closely to connect with connector 3153 It connects, the other end of connector 3153 and air port 31305 are affixed.
Further, ajutage 315 at least two, one end and the pneumatic actuator 311 of at least two ajutages 315 At least two connectors are affixed, another at least two filter 313 of difference is affixed.In the shown embodiment, ajutage 315 There are two altogether, one end of two ajutages 315 is affixed with two connectors of a pneumatic actuator 311 respectively, two air-supplies The one end of pipe 315 far from pneumatic actuator 311 is affixed with the air port of two filters 313 31305 respectively, simultaneously because two mistakes Filter 313 is tightly connected with two cofferdams 211 respectively, so that a pneumatic actuator 311 can give two cofferdams simultaneously 211 dispatch air, and make each cofferdam 211 and have a set of individual air path system, and then prevent in the long-term use Because cofferdam 211 pollutes, and multiple cofferdams 211 is caused to pollute the problem of, avoid between multiple cofferdams 211 Cross contamination further ensures the germ-free condition of cofferdam 211 in the long-term use.
Ball valve 317 is used to control the flow direction and flow velocity of air.The both ends of ajutage 315 pass through ball valve 317 and wind-force respectively Driver 311, filter 313 are affixed.By setting ball valve 317, the flow direction and flow velocity of air can be preferably controlled, meanwhile, When needing replacing pneumatic actuator 311 and ajutage 315, ball valve 317 can be closed, and then is conducive to pneumatic actuator 311 And the germ-free condition of the replacement and holding cofferdam 211 of ajutage 315.In addition, in the case where powering off the short time, can pass through Temporary close ball valve 317 is to keep the positive pressure inside cofferdam 211.
In the shown embodiment, ball valve 317 altogether there are four, two one end in four ball valves 317 respectively with wind-force The connector of driver 311, and the other end is affixed close to one end of pneumatic actuator 311 with two tube bodies 3151 respectively, so that Two ajutages 315 are affixed with two connectors of pneumatic actuator 311 respectively.Other two difference in two ball valves 317 Affixed with two one end of connector 3153 far from tube body 3151, the other end is solid with the air port of two filters 313 31305 respectively It connects, so that two ajutages 315 are affixed with two filters 313 respectively.It, can be with when needing to divulge information to cofferdam 211 Two ball valves 317 at one 315 both ends of ajutage are opened, it, can be by four balls when needing to divulge information to two cofferdams 211 Valve 317 is opened.
Pipe collar 319 is used to fix the junction of ajutage 315 and ball valve 317 and the connection of ball valve 317 and filter 313 Place.The both ends of ball valve 317 by pipe collar 319 respectively with the one end of filter 313, blast pipe 315 far from pneumatic actuator 311 It is affixed.Further, pipe collar 319 carry silica gel ring so that the both ends of ball valve 317 can closely with filter 313, the one end of blast pipe 315 far from pneumatic actuator 311 is affixed.By the way that pipe collar 319 is arranged so that ball valve 317 and filter 313, it installs and replaces between air-supply 315 and is more convenient.In the shown embodiment, there are four pipe collar 319 is total to, two ball valves 317 both ends are affixed with the one end of filter 313, blast pipe 315 far from pneumatic actuator 311 respectively by pipe collar 319.
Please refer to fig. 5, air draft component 310' is used to that the air in cofferdam 211 will to be exported, to realize cofferdam 211 In air exchange, balance cofferdam 211 pressure.Air draft component 310' includes being tightly connected filter with cofferdam 211 The structure of 313', filter 313' are identical as the structure of filter 313.Further, the connector 3139' of filter 313' is remote One end and the exhaust outlet of the second mounting surface 2114 from lid 31303' are tightly connected.Filter 313' be primary filter, in Imitate filter and high efficiency particulate air filter.Preferably, filter 313' is high efficiency particulate air filter, so that isolating device 10 can reach It cultivates germfree animal or carries out the standard of sterile working.
In the shown embodiment, filter 313' altogether there are two, two filter 313' respectively with two cofferdams 211 It is tightly connected, so that a cofferdam 211 corresponds to a filter 313', avoids two or more cofferdams 211 and share Cross contamination caused by a set of air draft component 310'.
Installation and disinfecting process before the use of above-mentioned isolating device 10 is specific as follows:
First lid 223 is put into cofferdam 211, by the connector 3139 of filter 313 close to the one of cofferdam 211 End, filter 313' connector 3139' sealed with film close to one end of cofferdam 211, and by filter 313 and filter 313' sterilizes for use.Wherein, film is wheat membrane, and sterilization method is moist heat sterilization.
Cofferdam 211 and transferring cabin 221 are tightly connected, and the first lid 223 and the second lid 225 are covered on respectively The both ends of transferring cabin 221.By the both ends of ajutage 315 by ball valve 317 respectively with the connector of pneumatic actuator 311, filtering The air port 31305 of device 313 is affixed.
By the air outlet of cofferdam 211 and exhaust outlet, filter 313 connector 3139 close to one end of cofferdam 211, After the connector 3139' of filter 313' sterilizes close to one end of cofferdam 211, the connector 3139 of filter 313 is leaned on One end of nearly cofferdam 211 is tightly connected with the air outlet of cofferdam 211.By the connector 3139' of filter 313' close to every One end and the exhaust outlet of cofferdam 211 from cabin 211 are tightly connected.Wherein, sterilization method is spray disinfectant, thimerosal two Chlorine monoxid or hydrogen peroxide.
All ball valves 317 are opened, the first lid 223 is removed from transferring cabin 221, open the second lid 225 Disinfection mouth 2251 and exhaust outlet 2253, from the disinfection mouth 2251 of the second lid 225 into transferring cabin 221 and cofferdam 211 Even spray disinfectant sterilizes, and after spray disinfectant, with 2254 enclosing sterilizing mouth 2251 of sealing element and exhaust outlet 2253, and closes Close all ball valves 317.Sterilizing 10 minutes~after twenty minutes, and by the connector of filter 313 3139 close to cofferdam 211 The film of the film of one end and the connector 3139' of filter 313' close to one end of cofferdam 211 punctures.Sterilizing 2 hours~4 is small First lid 223 is closely covered on transferring cabin 221 by Shi Hou by the mutual cooperation of operating gloves 217 and auxiliary member 219 One end far from the second lid 225, opens pneumatic actuator 311 and all ball valves 317 are aerated and take a breath, by exhaust duct The air port 31305 of the wind warp of 315 conveyings enters the gap of shell 3130 and filter core 3134, enters isolation after the filtering of filter core 3134 In cabin 211, and it is discharged by filter 313'.After ventilation 24 hours~48 hours, the sterility of isolating device 10 is examined It surveys, can be used when disclosure satisfy that actual needs.
The use process of above-mentioned isolating device 10 is specific as follows:
By germfree animal raising in box body 215, pneumatic actuator 311 and all ball valves 317 are opened, by filter 310 filtered filtrated airs enter in cofferdam 211, and cofferdam is discharged followed by box body 215 and filter 310' 211, to realize to the oxygen supply of germfree animal and the ventilation and ventilation of cofferdam 211.
When needing to transmit required article into cofferdam 211, after sterilisation of objects needed for cofferdam 211, through the Two lids 225 enter in transferring cabin 221, carry out disinfection to the outer surface spray disinfectant of required article in transferring cabin 221, And sealed in transferring cabin 221 45 minutes~120 minutes, finally pass through the first lid 223 and enters in cofferdam 211.Required After article enters cofferdam 211, by the mutual cooperation of operating gloves 217 and auxiliary member 219, closely by the first lid 223 It is covered on the one end of transferring cabin 221 far from the second lid 225.
When needing the defective work in cofferdam 211 passing out cofferdam 211, first by 221 sterilization of transferring cabin Afterwards, defective work is passed to through the first lid 223 in transferring cabin 221, then passes through the phase of operating gloves 217 and auxiliary member 219 Mutually cooperation, the one end of transferring cabin 221 far from the second lid 225 is closely covered on by the first lid 223.Open the second lid 225 and defective work is taken out, the second lid 225 is covered on the one end of transferring cabin 221 far from the first lid 223, and to passing 221 spray disinfectant of cabin is passed to carry out disinfection sterilizing.
Above-mentioned isolating device 10 has at least the following advantages:
(1) interrupter 200 of above-mentioned isolating device 10 includes barrier assembly 210 and transmitting assembly 220, barrier assembly 210 include cofferdam 211 and operating gloves 217, can carry out sterile working in cofferdam by operating gloves 217 or support Grow germfree animal.Cofferdam 211 is equipped with installing port, and transmitting assembly 220 includes transferring cabin 221, the first lid 223 and the second lid 225, transferring cabin 221 is arranged in installing port, and is tightly connected with cofferdam 211, by the way that transferring cabin 221 is arranged, be conducive to every Article is transmitted from 221 inside of cabin and passes out the article inside cofferdam 221.First lid 223 is contained in cofferdam 221 In, and it is covered on transferring cabin 221, the second lid 225 is covered on side of the transferring cabin 221 far from the first lid 223, passes through setting First lid 223 and the second lid 225, can seal transferring cabin 221, and then be conducive to keep transferring cabin 221 and cofferdam 211 germ-free condition.Again since barrier assembly 210 further includes auxiliary member 219, auxiliary member 219 is set with the interval of operating gloves 217 It sets, auxiliary member 219 is arranged close to installing port, and transferring cabin 221 is arranged in installing port, and auxiliary member 219 and operating gloves 217 can It cooperates, so that the first lid 223 is covered on transferring cabin 221, the mutual of auxiliary member 219 and operating gloves 217 can be passed through First lid 223 is more tightly sealed on transferring cabin 221 by cooperation, is avoided the occurrence of since the first lid 223 fails to close The problem of tightly making 211 microbiological contamination of cofferdam, and then ensure that the germ-free condition of cofferdam 211 so that above-mentioned isolating device 10 It can maintain germ-free condition the long period, and then be conducive to the Long-term breeding of germfree animal.Simultaneously as at least two ajutages 315 one end is affixed with pneumatic actuator 311, and the other end is affixed at least two filters 313 respectively, at least two filterings Device 313 is tightly connected at least two cofferdams 211 respectively so that pneumatic actuator 311 can give at least two cofferdams 211 Ventilation, and since each ajutage 315 is tightly connected through a filter 313 and a cofferdam 211, so that each isolation There is a set of individual air path system in cabin 211, and then prevents from causing because a cofferdam 211 pollutes in the long-term use The problem of multiple cofferdams 211 pollute avoids the cross contamination between multiple cofferdams 211, further ensures isolation The germ-free condition of cabin 211 in the long-term use.
(2) pneumatic actuator 311 of above-mentioned isolating device 10 totally one, there are two connections for a tool of pneumatic actuator 311 Mouthful, so that a pneumatic actuator 311 can give two 211 dispatch air of cofferdam simultaneously, pneumatic actuator can either be reinforced 311 service efficiency, and the generation of noise can be reduced.
(3) filter 313 and filter 313' of above-mentioned isolating device 10 can be subjected to the place that high temperature and pressure repeatedly sterilizes Reason, and then the cost of 211 contaminated risk of cofferdam and entire isolating device 10 can be reduced.Meanwhile filter 313 and mistake Filter 313' is both preferably high efficiency particulate air filter, so that isolating device 10 can reach cultivation germfree animal or carry out sterile behaviour The standard of work.
(4) both ends of the ajutage 315 of above-mentioned isolating device 10 pass through ball valve 317 and pneumatic actuator 311, filtering respectively Device 313 is affixed.By the way that ball valve 317 is arranged, the flow direction and flow velocity of air can be preferably controlled, meanwhile, when needing replacing wind-force When driver 311 and ajutage 315, ball valve 317 can be closed, and then is conducive to pneumatic actuator 311 and ajutage 315 more Change and keep the germ-free condition of cofferdam 211.In addition, in the case where powering off the short time, temporary close ball valve 317 can be passed through To keep the positive pressure inside cofferdam 211.
(5) both ends of the ball valve 317 of above-mentioned isolating device 10 pass through the air inlet with filter 313 respectively of pipe collar 319 31305, the one end of blast pipe 315 far from pneumatic actuator 311 is affixed, convenient for ball valve 317 and filter 313, ajutage 315 it Between installation and replacement.
(6) above-mentioned isolating device 10 can reach germ-free condition, and be able to maintain that the germ-free condition of long period, both can be with For carrying out sterile working and cultivation germfree animal, the animal for cultivating other ranks, such as SPF (Specific can be used for Pathogen Free, no-special pathogen) grade animal.
It is appreciated that the quantity of column 112 is not limited to four, or three, can also be six, can be according to reality Border needs to be configured.Correspondingly, the quantity of slide assemblies 120 is not limited to four, or three, can be with six, it can To be configured according to actual needs, as long as ensureing that one end of a slide assemblies 120 and a column 112 is affixed, so that sliding Dynamic component 120 supporting frame 110 and can keep frame body 110 free to slide and stop bit.
It is appreciated that the quantity of erecting bed 114 is not limited to four, or one, can be with three, it can be according to reality Border needs to be configured.It is appreciated that the quantity of cofferdam 211 is not limited to two, or one, can also be three, It can be configured according to actual needs.It is appreciated that the quantity for the fixing piece 214 that each cofferdam 211 is arranged is not limited to four It is a, can be two, or five, as long as ensureing that cofferdam 211 can be steadily set on erecting bed 114.
It is appreciated that the shape of cofferdam 211 be not limited to it is cube shaped, or it is cylindrical, can as needed into Row setting.It is appreciated that cofferdam 211 is not limited to the transparent cabins PVC, and can also be the transparent cabins PU, it can be according to practical feelings Condition is configured, as long as ensureing that cofferdam 211 is transparent and is able to maintain that germ-free condition.
It is appreciated that the quantity of the objective table 2131 of mounting bracket 213 is not limited to three, and can also be four, it can basis Actual conditions are configured.When the tool of mounting bracket 213 is there are four when objective table 2131, four objective tables 2131 interval and parallel set It sets, so that mounting bracket 213 is four layer architectures.Further, one in four objective tables 2131 and cofferdam 211 are close to pulley The side of component 120 abuts, so that box body 215 can be placed on the objective table 2131, avoids box body 215 directly and cofferdam 211 abut and cofferdam 211 are caused to wear.
It is appreciated that auxiliary member 219 is not limited to the first mounting surface 2112 of cofferdam 211 to close to the second mounting surface 2114 direction is recessed the groove to be formed, and can also be the soft bag being tightly connected with cofferdam 211.When auxiliary member 219 is soft bag When, auxiliary member 219 is arranged in the first mounting surface 2112, and is arranged close to installing port, and auxiliary member 219 is spaced with operating gloves 217 Setting, side of the auxiliary member 219 far from the first mounting surface 2112 can be supported with the first side of the lid 223 far from transferring cabin 221 It connects, to allow the operator to the first lid 223 through the mutual cooperation of auxiliary member 219 and operating gloves 217 closely It is covered on the side of transferring cabin 221.Further, when auxiliary member 219 is soft bag, auxiliary member 219 is PVC bags, by PVC film It is made.
It is appreciated that the quantity of the auxiliary member 219 on a cofferdam 211 is not limited to one, or two, may be used also Think multiple.When auxiliary member 219 is two, two auxiliary members 219 are arranged at intervals on the first mounting surface 2112, two auxiliary Part 219 can be separately positioned on the both sides of installing port, and two auxiliary members 219 can also be arranged in the same side of installing port, but need Ensure that at least one of two auxiliary members 219 are located at the both sides of installing port with operating gloves 217.When auxiliary member 219 Quantity be it is multiple when, multiple auxiliary members 219 are arranged at intervals on the first mounting surface 2112, but need to ensure multiple auxiliary members At least one of 219 are located at the both sides of installing port with operating gloves 217.
It is appreciated that the shape of transferring cabin 221 is not limited to tubbiness, or it is cube shaped, it can carry out as needed Setting.Correspondingly, the square cover for being shaped to match with transferring cabin 221 of the first lid 223, and the second lid 225 It is shaped to the square cover to match with transferring cabin 221.
It is appreciated that the quantity of pneumatic actuator 311 is not limited to one, or two.When pneumatic actuator 311 When quantity is two, two pneumatic actuators 311 can give two 211 dispatch air of cofferdam, two pneumatic actuators simultaneously 311 can also give two 211 dispatch air of cofferdam respectively.
It is appreciated that the quantity of a 211 corresponding filter 313 of cofferdam is not limited to one, or multiple, root It is configured according to situation.When a cofferdam 211 corresponds to multiple filters 313, multiple filters 313 can be connected, into And effectively ensure the germ-free condition of cofferdam 211.
It is appreciated that the quantity of ball valve 317 is not limited to four, or three, can also be five, can be according to reality Border needs to be configured.When the quantity of ball valve 317 is three, one one end in two ajutages 315 needs and filtering Device 313 or pneumatic actuator 311 are directly affixed.It, can be by two in five ball valves 317 when the quantity of ball valve 317 is five A ball valve 317 is connected.It is appreciated that ball valve 317 can also change throttle valve and other kinds of valve into, as long as sky can be controlled The flow direction and flow velocity of gas.
It is appreciated that the quantity of a 211 corresponding filter 313' of cofferdam is not limited to one, or it is multiple, According to circumstances it is configured.When a cofferdam 211 corresponds to multiple filter 313', multiple filter 313' can be gone here and there Connection, and then effectively ensure the germ-free condition of cofferdam 211.
Test:
The object tested below is to above-mentioned isolating device 10 and cofferdam 211.
(1) according to national standard GB/T 14926.41-2001 in the cofferdam of above-mentioned isolating device aseptic condition and cultivation The aseptic condition of excrement of germfree animal be detected.Concrete operations are as follows:
(a) the aseptic condition detection in cofferdam:Aseptic feed is transmitted into cofferdam, passes through auxiliary member and operating gloves Mutual cooperation the first cover cap is set to transferring cabin, and incoming aseptic feed is stored in cofferdam, is periodically taken sterile Feed simultaneously measures its aseptic condition, to characterize the aseptic condition in cofferdam.Experimental result refers to table 1.
(b) the aseptic condition detection of the excrement of germfree animal:Germfree mouse is put into cofferdam, auxiliary member and behaviour are passed through First cover cap is set to transferring cabin by the mutual cooperation for making gloves, and sterile animal is cultivated 12 months in cofferdam, fixed When take the excrement of mouse and measure its aseptic condition.Experimental result refers to table 1.
What table 1 indicated is the aseptic condition of the excrement of the aseptic condition and germfree animal in cofferdam.
Table 1
As can be seen from Table 1, aseptic feed is transmitted into cofferdam, is placed 12 months, is still not detected in aseptic feed thin Bacterium and fungi illustrate that aseptic feed still in germ-free condition, further relates to cofferdam placement and still is able within 12 months keep asepsis ring Border, and then be conducive to the cultivation of germfree animal.Meanwhile germfree animal being cultivated 12 months in cofferdam, the excrement of germfree animal Just bacterium and fungi are still not detected in, illustrates germfree animal still in germ-free condition, need can be cultivated by further relating to isolating device Cultivate the germfree animal of long period.
(2) influence according to the transmission of national standard GB/T 14926.41-2001 measurement articles to the aseptic condition of cofferdam. Concrete operations are as follows:
After cofferdam spray disinfectant liquid disinfectant, aseptic feed is passed in cofferdam, auxiliary member and operating gloves are passed through Mutual cooperation the first cover cap is set to transferring cabin, aseptic feed is placed 10 minutes in cofferdam, and by aseptic feed Cofferdam is spread out of, then the first cover cap is set to by transferring cabin by the mutual cooperation of auxiliary member and operating gloves, it as will be sterile Feed transmits primary.Same aseptic feed is repeatedly transmitted.Timing measures the aseptic condition of the aseptic feed of outflow.It is real It tests the results detailed in Table 2.
What table 2 indicated is influence of the transmission to the aseptic condition of cofferdam of article.
Table 2
As can be seen from Table 2, aseptic feed carries out 32 transmission in isolating device, and bacterium is still not detected in aseptic feed And fungi, illustrate that aseptic feed is transmitted through 32 times still in germ-free condition, illustrates in transmittance process through auxiliary member and operation The mutual cooperation of gloves by the first cover cap be set to transferring cabin, can make the first lid it is even closer be covered on transferring cabin, into And effectively keep the gnotobasis in cofferdam.
Each technical characteristic of embodiment described above can be combined arbitrarily, to keep description succinct, not to above-mentioned reality It applies all possible combination of each technical characteristic in example to be all described, as long as however, the combination of these technical characteristics is not deposited In contradiction, it is all considered to be the range of this specification record.
Above-described embodiments merely represent several embodiments of the utility model, the description thereof is more specific and detailed, But therefore it can not be interpreted as the limitation to utility model patent range.It should be pointed out that for the common skill of this field For art personnel, without departing from the concept of the premise utility, various modifications and improvements can be made, these are belonged to The scope of protection of the utility model.Therefore, the protection domain of the utility model patent should be determined by the appended claims.

Claims (10)

1. a kind of isolating device, which is characterized in that including interrupter and ventilating mechanisms;
The interrupter includes barrier assembly and transmitting assembly, and the barrier assembly and the transmitting assembly are at least two A, each barrier assembly includes cofferdam, operating gloves and auxiliary member, and the cofferdam is equipped with installing port, the operation Gloves are tightly connected with the cofferdam, and the auxiliary member is arranged with the operating gloves interval, and the auxiliary member is close to institute Installing port setting is stated, the auxiliary member is tightly connected with the cofferdam, and each transmitting assembly includes transferring cabin, the first lid Body and the second lid, the transferring cabin is arranged in the installing port, and is tightly connected with the cofferdam, and first lid is received It is dissolved in the cofferdam, and is covered on the side of the transferring cabin, second cover cap is set to the transferring cabin far from institute State the side of the first lid, wherein the auxiliary member and the operating gloves can cooperate, so that first cover cap Set on the transferring cabin;
The ventilating mechanisms include air-supply assembly, and the air-supply assembly includes pneumatic actuator, ajutage and filter, described to send Air hose and the filter are at least two, and one end of at least two ajutages is affixed with the pneumatic actuator, The other end is affixed at least two filters respectively, at least two filters respectively at least two cofferdams It is tightly connected.
2. isolating device according to claim 1, which is characterized in that the auxiliary member is that the cofferdam is recessed inwardly shape At groove;Or,
The auxiliary member is soft bag.
3. isolating device according to claim 1, which is characterized in that the auxiliary member is one, an auxiliary member The both sides of the installing port are separately positioned on the operating gloves;Or,
The auxiliary member at least two, at least two auxiliary member interval settings, and it is separately positioned on the installing port Both sides.
4. isolating device according to claim 1, which is characterized in that the cofferdam is the cabins PVC or the cabins PU;And/or
The auxiliary member is PVC bags or PU bags;And/or
The operating gloves include glove bulk and connecting cylinder, and one end of the glove bulk and the connecting cylinder is tightly connected, The other end of the connecting cylinder is tightly connected with the cofferdam, and the glove bulk is butyronitrile gloves, and the connecting cylinder is PVC Cylinder or PU;And/or
The transferring cabin is the cabins PC.
5. isolating device according to claim 1, which is characterized in that second lid includes lid main body and sealing Part, the lid main body setting disinfection mouth, the sealing element are inserted in the disinfection mouth.
6. isolating device according to claim 1, which is characterized in that each filter includes shell and filter core, institute It states filter core and is contained in the shell, and is affixed with the shell, the filter core is tightly connected with the cofferdam, so that the filter Core and the cofferdam communicate.
7. isolating device according to claim 1, which is characterized in that the pneumatic actuator has at least two connections Mouthful, one end of at least two ajutages is affixed at least two connectors respectively, and the other end is respectively at least two The filter is affixed, and at least two cofferdams are equipped with air outlet, and at least two filters are respectively at least two The air outlet of a cofferdam is tightly connected.
8. isolating device according to claim 1, which is characterized in that the air-supply assembly includes ball valve, and the ball valve is extremely Less be two, one end of at least two ball valves is affixed at least two filters respectively, the other end respectively at least Two one end of the ajutage far from the pneumatic actuator are affixed.
9. isolating device according to claim 8, which is characterized in that the air-supply assembly includes pipe collar, and the pipe collar is At least two pairs, one end of each ball valve is affixed by a pipe collar and a filter, and the other end passes through one A pipe collar and an one end of the ajutage far from the pneumatic actuator are affixed.
10. isolating device according to claim 1, which is characterized in that the ventilating mechanisms further include air draft component, described Side of the cofferdam far from the air-supply assembly is arranged in air draft component, and is tightly connected with the cofferdam.
CN201721450999.5U 2017-11-02 2017-11-02 Isolating device Active CN207678573U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201721450999.5U CN207678573U (en) 2017-11-02 2017-11-02 Isolating device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201721450999.5U CN207678573U (en) 2017-11-02 2017-11-02 Isolating device

Publications (1)

Publication Number Publication Date
CN207678573U true CN207678573U (en) 2018-08-03

Family

ID=62989654

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201721450999.5U Active CN207678573U (en) 2017-11-02 2017-11-02 Isolating device

Country Status (1)

Country Link
CN (1) CN207678573U (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110278920A (en) * 2019-04-22 2019-09-27 嵊州陌桑高科股份有限公司 A kind of formula supply air system from inside to outside being assemblied in industrial aquaculture room
CN110447547A (en) * 2019-09-10 2019-11-15 赛业(苏州)生物科技有限公司 Sterilized isolator
CN112493149A (en) * 2020-10-28 2021-03-16 王绪明 Sterile feeding box and using method
CN113367069A (en) * 2021-06-17 2021-09-10 温州医科大学 Multifunctional experimental animal barrier environment facility air conditioning system

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110278920A (en) * 2019-04-22 2019-09-27 嵊州陌桑高科股份有限公司 A kind of formula supply air system from inside to outside being assemblied in industrial aquaculture room
CN110447547A (en) * 2019-09-10 2019-11-15 赛业(苏州)生物科技有限公司 Sterilized isolator
CN112493149A (en) * 2020-10-28 2021-03-16 王绪明 Sterile feeding box and using method
CN113367069A (en) * 2021-06-17 2021-09-10 温州医科大学 Multifunctional experimental animal barrier environment facility air conditioning system

Similar Documents

Publication Publication Date Title
CN207678573U (en) Isolating device
CN101524051B (en) Multi-functional medium-sized animal breeding isolation system
CN101400779B (en) Incubator for isolator
US8883492B2 (en) Cell culture apparatus
CN102328317A (en) Soft cabin isolator
CN201403389Y (en) Middle animal feed isolator for high-level biology safe laboratory
CN202315914U (en) Inspection isolator
CN103436443B (en) Integration zero leakage gas positive-negative pressure compatible microorganism isolated operation cabinet
CN108641925A (en) A kind of microbiological incubator
CN207616624U (en) Isolating device
CN208933375U (en) Multifunctional microbial detection device
CN105684920A (en) Breed conservation isolator for genetic engineering mice
CN102500434A (en) Isolator for sterility detection process
CN202387473U (en) Sterile isolation system
CN205567398U (en) Gene engineering mouse breed conservation isolator
CN111334429A (en) Modular multifunctional cell workstation
CN202366716U (en) Isolator with soft cabin body
CN203440380U (en) Integrated zero-gas-leakage microorganism isolation operation cabinet with positive and negative pressure
CN106212304A (en) A kind of concurrent flow Sterilized isolator
CN207855814U (en) Medium and small animal organism aerosol mouth and nose exposure system
CN205235000U (en) Sterilization is planted with high -efficient, intensive ozone workplace to domestic fungus
Vowles et al. Gnotobiotic mouse technology: an illustrated guide
CN202773488U (en) Inoculation box
CN112931258A (en) Independent ventilation type monkey negative pressure isolating device
CN2786130Y (en) Open type ultra-clean box

Legal Events

Date Code Title Description
GR01 Patent grant
GR01 Patent grant
CB03 Change of inventor or designer information
CB03 Change of inventor or designer information

Inventor after: Liu Jie

Inventor after: Wang Xiaolei

Inventor after: Shang Haitao

Inventor after: Wang Cong

Inventor after: Jiang Jipeng

Inventor after: Yu Mubiao

Inventor before: Liu Jie

Inventor before: Wang Xiaolei

Inventor before: Shang Haitao

Inventor before: Wang Cong

Inventor before: Jiang Jipeng

Inventor before: Yu Mubiao

Inventor before: Wei Hong

TR01 Transfer of patent right
TR01 Transfer of patent right

Effective date of registration: 20220711

Address after: 430200 room 8802, No. 4, workshop 04, building 25, phase 3.1, Wuhan Optics Valley International Biomedical enterprise accelerator, No. 388, Gaoxin Second Road, East Lake New Technology Development Zone, Wuhan, Hubei Province

Patentee after: WUHAN HUALIANKE BIOTECHNOLOGY CO.,LTD.

Address before: 518000 Room 201, building A, No. 1, Qian Wan Road, Qianhai Shenzhen Hong Kong cooperation zone, Shenzhen, Guangdong (Shenzhen Qianhai business secretary Co., Ltd.)

Patentee before: SHENZHEN QIANHAI JINZHUO BIOTECHNOLOGY CO.,LTD.