CN107930704A - A kind of bio-safety isolating device - Google Patents
A kind of bio-safety isolating device Download PDFInfo
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- CN107930704A CN107930704A CN201711407717.8A CN201711407717A CN107930704A CN 107930704 A CN107930704 A CN 107930704A CN 201711407717 A CN201711407717 A CN 201711407717A CN 107930704 A CN107930704 A CN 107930704A
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- 238000005422 blasting Methods 0.000 claims abstract description 31
- 238000003825 pressing Methods 0.000 claims description 27
- 238000005070 sampling Methods 0.000 claims description 22
- 239000000443 aerosol Substances 0.000 claims description 17
- 230000001954 sterilising effect Effects 0.000 claims description 15
- 238000004659 sterilization and disinfection Methods 0.000 claims description 15
- 238000003860 storage Methods 0.000 claims description 12
- 238000012544 monitoring process Methods 0.000 claims description 11
- 238000001514 detection method Methods 0.000 claims description 5
- 238000011065 in-situ storage Methods 0.000 claims description 4
- 244000000010 microbial pathogen Species 0.000 abstract description 8
- 108010066114 cabin-2 Proteins 0.000 description 14
- 238000000034 method Methods 0.000 description 7
- 239000010408 film Substances 0.000 description 6
- 238000002955 isolation Methods 0.000 description 6
- 238000001914 filtration Methods 0.000 description 5
- 239000000126 substance Substances 0.000 description 5
- 238000010586 diagram Methods 0.000 description 4
- 239000010409 thin film Substances 0.000 description 4
- 230000009471 action Effects 0.000 description 3
- 238000005056 compaction Methods 0.000 description 3
- 239000000645 desinfectant Substances 0.000 description 3
- 238000002474 experimental method Methods 0.000 description 3
- 239000002245 particle Substances 0.000 description 3
- 229920003023 plastic Polymers 0.000 description 3
- 230000004888 barrier function Effects 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 230000007246 mechanism Effects 0.000 description 2
- 239000004033 plastic Substances 0.000 description 2
- 231100000614 poison Toxicity 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 230000005180 public health Effects 0.000 description 2
- 230000009467 reduction Effects 0.000 description 2
- 208000032163 Emerging Communicable disease Diseases 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 230000006835 compression Effects 0.000 description 1
- 238000007906 compression Methods 0.000 description 1
- 230000007797 corrosion Effects 0.000 description 1
- 238000005260 corrosion Methods 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000003828 downregulation Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000001125 extrusion Methods 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 239000007769 metal material Substances 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 239000002574 poison Substances 0.000 description 1
- 230000007096 poisonous effect Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L1/00—Enclosures; Chambers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
- A61L2/08—Radiation
- A61L2/10—Ultraviolet radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L9/00—Disinfection, sterilisation or deodorisation of air
- A61L9/16—Disinfection, sterilisation or deodorisation of air using physical phenomena
- A61L9/18—Radiation
- A61L9/20—Ultraviolet radiation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D46/00—Filters or filtering processes specially modified for separating dispersed particles from gases or vapours
- B01D46/56—Filters or filtering processes specially modified for separating dispersed particles from gases or vapours with multiple filtering elements, characterised by their mutual disposition
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B25—HAND TOOLS; PORTABLE POWER-DRIVEN TOOLS; MANIPULATORS
- B25J—MANIPULATORS; CHAMBERS PROVIDED WITH MANIPULATION DEVICES
- B25J21/00—Chambers provided with manipulation devices
- B25J21/02—Glove-boxes, i.e. chambers in which manipulations are performed by the human hands in gloves built into the chamber walls; Gloves therefor
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- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Mechanical Engineering (AREA)
- Robotics (AREA)
- Clinical Laboratory Science (AREA)
- Accommodation For Nursing Or Treatment Tables (AREA)
Abstract
The invention discloses a kind of bio-safety isolating device, including air-tightness pass-through box, flexible negative-pressure operation cabin, blasting high-efficiency filter, level-one air draft high efficiency particulate air filter and two level air draft effective filter, air-tightness pass-through box includes forms, flexible negative-pressure operation cabin includes nacelle and detachable support frame, and nacelle is fexible film nacelle；Blasting high-efficiency filter is arranged at outside nacelle, and blasting high-efficiency filter inside nacelle with connecting；Level-one air draft high efficiency particulate air filter is arranged at outside nacelle, and level-one air draft high efficiency particulate air filter inside nacelle with connecting；Two level air draft effective filter is arranged at outside nacelle, including two level air draft high efficiency particulate air filter and exhaust blower, and two level air draft high efficiency particulate air filter both ends are connected with level-one air draft high efficiency particulate air filter and exhaust blower respectively.The bio-safety isolating device maneuverability, biological safe type isolating device safe and reliable, ambient adaptability is strong, available for the progress pathogenic microorganism isolated operation under negative pressure state.
Description
Technical field
The present invention relates to biological safety protection technical field, more particularly to a kind of bio-safety isolating device.
Background technology
Bioaerosol can be produced in the operating process such as the pathogenic microorganism examination, experiment are carried out, if harmful organism gas
Colloidal sol is diffused in laboratory, it will the infection risk of staff, serious threat human life and health, or even dirt is significantly greatly increased
Surrounding environment is contaminated, triggers great public health event.In order to effectively improve the personal safety of staff, it is necessary to establish safety can
The operating environment leaned on.
Biocontainment laboratory, is to avoid or control the harmful organism factor operated by protective barrier and management measure
Harm, reaches the biology laboratory and Animal Lab. of bio-safety requirement.The high-grade life used in biocontainment laboratory
Thing safety barrier generally use metal material or rigid plastics make, and China is vast in territory, and epidemic-stricken area geographical environment is complicated more
Become, biocontainment laboratory because its quality it is heavier, it is bulky, be not easy to be moved or carry, long distance transportation, cause it
It is difficult to meet the requirements of one's work such as the quick development the pathogenic microorganism examination in epidemic-stricken area scene.
At present, flexible thin film type isolator has been supplied in the clean environments such as pharmacy, hospital, but is generally insulated in device in just
Pressure, is usually used in aseptic operation, can not effectively prevent the leakage of harmful substance, is not suitable for operating pathogenic microorganism.It is high
Degree biological safety insulating device not only needs to establish the operating environment of closed isolation, it is also necessary to stable subnormal ambient is established,
Current flexible thin film type isolator can not meet this requirement.
The public health event abilities such as burst, emerging infectious disease, biological terrorist are tackled to improve China, are met vast
Inspection and quarantine requirements of one's work are carried out in agriculture and animal husbandry and outlying district, there is an urgent need to maneuverability, safe and reliable, ambient adaptability by force
Biological safe type isolating device.
The content of the invention
The object of the present invention is to provide a kind of maneuverability, the biological safe type isolation that safe and reliable, ambient adaptability is strong
Device, to solve the above-mentioned problems of the prior art, makes it can be used for carrying out pathogenic microorganism isolation behaviour under negative pressure state
Make.
To achieve the above object, the present invention provides following scheme：
The present invention provides a kind of bio-safety isolating device, including：Air-tightness pass-through box, flexible negative-pressure operation cabin, air-supply
High efficiency particulate air filter, level-one air draft high efficiency particulate air filter and two level air draft effective filter, the air-tightness pass-through box include forms,
The forms on two different side walls in being respectively equipped with the first pressing door and the second pressing door；The flexibility negative-pressure operation cabin includes
Nacelle and detachable support frame, the detachable support frame are used to support the nacelle, and the nacelle is fexible film cabin
Body, the nacelle are connected with the forms air-tightness, and after opening second pressing door, the forms inside the nacelle with connecting
It is logical；The blasting high-efficiency filter is arranged at outside the nacelle, and the gas outlet of the blasting high-efficiency filter and the nacelle
Inside connection；The level-one air draft high efficiency particulate air filter is arranged at outside the nacelle, and the level-one air draft high efficiency particulate air filter into
Gas port inside the nacelle with connecting；The two level air draft effective filter is arranged at outside the nacelle, including two level air draft
High efficiency particulate air filter and exhaust blower, and the air inlet of the two level air draft high efficiency particulate air filter and the level-one air draft high efficiency particulate air filter
Gas outlet connects, and the gas outlet of the two level air draft high efficiency particulate air filter is connected with the exhaust blower.
Preferably, the forms, which are provided with the side wall of second pressing door, is connected with first flange, and the nacelle is led to
Cross a second flange to be connected with the first flange air-tightness, the first flange is equipped with the inlet air connected with the nacelle
Mouthful, the blasting high-efficiency filter is arranged on the outer top surface of the forms and is connected by air inlet pipeline with the air inlet.
Preferably, the first flange is equipped with a power supply socket on the side wall inside the nacelle and a pressure difference is supervised
Display device is surveyed, the pressure difference monitoring display device is used to monitor and show the nacelle internal pressure, outside the forms
A high efficiency particulate air filter and an electric appliance control box are provided with top surface, the high efficiency particulate air filter connects inside the forms and air,
The forms are internally provided with ultraviolet lamp, and the power supply socket, pressure difference monitoring display device and the ultraviolet lamp are equal
It is electrically connected with the electric appliance control box, the electric appliance control box is electrically connected with external power supply.
Preferably, the two level air draft effective filter further includes a pressure difference control device and storage battery, the pressure difference
Control device includes differential pressure pickup and control system, and an instrument filter, the differential pressure pickup are provided with the nacelle
Connected by pipeline with the gas outlet of the instrument filter, the differential pressure pickup is electrically connected with the control system, described
Control system and the air draft mechatronics, the storage battery and the control system and the air draft mechatronics, the storage
Battery is electrically connected with external power supply.
Preferably, multiple glove holes are additionally provided with the operating surface in the flexible negative-pressure operation cabin, each glove hole
Hermetic seal is connected with a gloves, and the gloves include oversleeve, cuff ring and glove bulk, each glove hole and an institute
One end hermetic seal connection of oversleeve is stated, the other end of the oversleeve is connected with the inner of the cuff ring, outside the cuff ring
End is stretched in the oversleeve, is provided with multiple card slots on each cuff ring outer wall, the glove bulk passes through elastic rubber
Cushion rubber is fixed in a card slot.
Preferably, the oversleeve is fixed on by the elastic rubber ring in the card slot of described cuff ring the inner.
Preferably, the detachable support frame includes more seamed edge supporting rods and multiple seamed edge fasteners, the nacelle
For polyhedron, a seamed edge connecting sleeve is both provided with each seamed edge of the nacelle, and operating surface is only in each of operating surface
Seamed edge is equipped with a seamed edge connecting sleeve, and a seamed edge support is equipped with each seamed edge connecting sleeve
Bar, passes through the seamed edge fastener between adjacent two seamed edge supporting rods and connects, the appearance of the operating surface of the nacelle
Operating surface is provided with face and tenses casing, it is transparent casing that the operating surface, which tenses casing, and the operating surface tenses to be worn in casing
Equipped with a tension rope, the both ends of the tension rope are fixedly connected with the seamed edge supporting rod at operating surface both ends；The operating surface
Setting is tilted backwards from the bottom to top.
Preferably, the detachable support frame further includes side wall support bar and side wall fastener, the nacelle with institute
State on the outer surface of the opposite side wall of operating surface and at least one side wall be equipped with the outer top surface of the nacelle and tense casing,
Each side wall, which is tensed in casing, is equipped with a side wall support bar, and the both ends of the side wall support bar pass through the side
The seamed edge supporting rod on the surface that wall fastener is supported with the side arm supports bar is connected.
Preferably, polylith hard operation tablet, the level-one air draft high efficiency particulate air filter are equipped with the nacelle inner bottom surface
It is installed on the top of the nacelle by a support plate respectively with the two level air draft effective filter, each support
Plate with two adjacent side wall support bars and/or the seamed edge supporting rod are fixedly connected on top surface outside the nacelle, even
The exhaust pipeline end for connecing the level-one air draft high efficiency particulate air filter and the two level air draft high efficiency particulate air filter is equipped with the first aerosol
Thief hatch, the pipeline for connecting the two level air draft high efficiency particulate air filter and the exhaust blower are equipped with the second sampling of aerosol mouth.
Preferably, the exhaust pipeline end of the level-one air draft high efficiency particulate air filter and the two level air draft high efficiency particulate air filter is connected
End is equipped with the first sampling of aerosol mouth, realizes that the in situ of the level-one air draft high efficiency particulate air filter is examined to connect air sampling rig
Leakage, the pipeline for connecting the two level air draft high efficiency particulate air filter and the exhaust blower are equipped with the second sampling of aerosol mouth, with connection
Air sampling rig realizes the leak detection in situ of the two level air draft high efficiency particulate air filter；
Further include a sterilizing equipment decontaminating apparatus, the air outlet of the two level air draft effective filter and the blasting high-efficiency filter
Air inlet by sterilize connecting line connect, the sterilizing equipment decontaminating apparatus be arranged at it is described disinfection connecting line on or the nacelle
It is interior.
The present invention achieves following technique effect relative to the prior art：
Bio-safety isolating device provided by the invention can be folded storage and rapid deployment.The flexible negative pressure of the device
The nacelle of operational window is made of fexible film, has gathering property.During gathering, detachable support frame is pulled down, can be incited somebody to action
Flexible negative-pressure operation lock pressure contracting is collapsed.Normal operating condition, nacelle are equipped with exhaust outlet and air inlet, and nacelle passes through exhaust outlet one
Level air draft high efficiency particulate air filter connection, nacelle is connected by air inlet with blasting high-efficiency filter, and air inlet and blasting high-efficiency mistake
Pressure fan is not set between filter, only an exhaust blower is connected with after two level air draft high efficiency particulate air filter, in the swabbing action of exhaust blower
Under, air can produce resistance when passing through blasting high-efficiency filter, so as to form in nacelle the negative pressure outside with respect to nacelle, air-flow just meeting
Enter from out of my cabin in cabin.Bio-safety isolating device provided by the invention employs level-one air draft high efficiency particulate air filter and two level air draft
Effective filter carries out double-filtration to discharge air so that the gas of two level air draft effective filter discharge is practically free of
Harmful substance, can directly be thrown into interior, certainly, also may be selected gas being thrown into outdoor.Level-one air draft high efficiency particulate air filter and
Two level air draft effective filter is respectively positioned on outside nacelle, and is filtered with the gas inside exhaust blower suction nacelle, due to
Level-one air draft high efficiency particulate air filter and two level air draft high efficiency particulate air filter equally can produce resistance to air flow, so, connect level-one
The pipeline and connection two level air draft high efficiency particulate air filter of air draft high efficiency particulate air filter and two level air draft high efficiency particulate air filter and exhaust blower
The negative pressure outside to nacelle can be formed in pipeline so that the gas inside nacelle can only be sequentially entered by the exhaust outlet in nacelle
Filtered, finally discharged, without in nacelle and one in level-one air draft high efficiency particulate air filter and two level air draft high efficiency particulate air filter
The junction or the junction of level-one air draft high efficiency particulate air filter and two level air draft high efficiency particulate air filter of level air draft high efficiency particulate air filter are formed
Leakage, security performance are more preferable.
Further, a kind of bio-safety isolating device of present invention offer can conveniently realize that online replace is broken on the outside of nacelle
The glove bulk of damage, has good operation ease.
Brief description of the drawings
In order to illustrate more clearly about the embodiment of the present invention or technical scheme of the prior art, below will be to institute in embodiment
Attached drawing to be used is needed to be briefly described, it should be apparent that, drawings in the following description are only some implementations of the present invention
Example, for those of ordinary skill in the art, without creative efforts, can also obtain according to these attached drawings
Obtain other attached drawings.
Fig. 1 is the overall structure diagram of bio-safety isolating device provided by the invention；
Fig. 2 is the structure diagram of the air-tightness pass-through box of bio-safety isolating device provided by the invention；
Fig. 3 is the internal structure signal of the two level air draft effective filter of bio-safety isolating device provided by the invention
Figure；
Fig. 4 is the structure diagram of the gloves of bio-safety isolating device provided by the invention；
Fig. 5 is the close-up schematic view at A in Fig. 4；
Fig. 6 is the structure diagram of the cuff ring of bio-safety isolating device provided by the invention.
Fig. 7 is that the principle that bio-safety isolating device Interior Disinfection equipment provided by the invention is sterilized into promoting the circulation of qi (vapour) body is shown
It is intended to；
Fig. 8 is that the principle that the external sterilizing equipment decontaminating apparatus of bio-safety isolating device provided by the invention is sterilized into promoting the circulation of qi (vapour) body is shown
It is intended to；
In figure：1- air-tightness pass-through boxes；2- flexibility negative-pressure operations cabin；3- seamed edges supporting rod, 4- first flanges；The second methods of 5-
It is blue；6- stents；The first pressing doors of 7-；The second pressing doors of 8-；9- mechanical compactions mechanism；10- ultraviolet lamps；11- pressure release high efficiency filters
Device；12- electric control box；13- ultraviolet violet light switch buttons；14- air inlets；15- power supply sockets；The monitoring display of 16- pressure differences
Device；17- blasting high-efficiency filters；18- level-one air draft high efficiency particulate air filters；19- exhaust pipelines；20- two level air draft high efficiency filters
Device；21- the first sampling of aerosol mouths；23- instrument filters；24- seamed edge fasteners；25- seamed edge connecting sleeves；26- is tensed
Rope；27- hard operates tablet；28- oversleeves；29- cuff rings；30- glove bulks；The first card slots of 31-；The second card slots of 32-；33-
Second sampling of aerosol mouth；34- two level air draft high efficiency particulate air filters；35- exhaust blowers；36- operating surfaces；37- operating surfaces tense casing；
38- side wall support bars；39- side walls tense casing；40- support plates；41- side wall fasteners；42- sterilizing equipment decontaminating apparatus；43- disinfection connections
Pipeline.
Embodiment
Below in conjunction with the attached drawing in the embodiment of the present invention, the technical solution in the embodiment of the present invention is carried out clear, complete
Site preparation describes, it is clear that described embodiment is only part of the embodiment of the present invention, instead of all the embodiments.It is based on
Embodiment in the present invention, those of ordinary skill in the art are obtained every other without making creative work
Embodiment, belongs to the scope of protection of the invention.
The object of the present invention is to provide a kind of maneuverability, the biological safe type isolation that safe and reliable, ambient adaptability is strong
Device, to solve the above-mentioned problems of the prior art, makes it can be used for carrying out pathogenic microorganism isolation behaviour under negative pressure state
Make.
In order to make the foregoing objectives, features and advantages of the present invention clearer and more comprehensible, it is below in conjunction with the accompanying drawings and specific real
Applying mode, the present invention is described in further detail.
The present invention provides a kind of bio-safety isolating device, and as shown in Figure 1, Figure 3, including air-tightness pass-through box 1, flexibility are negative
Press operation cabin 2, blasting high-efficiency filter 17, level-one air draft high efficiency particulate air filter 18 and two level air draft effective filter 20, it is airtight
Property pass-through box 1 include forms, for forms in being respectively equipped with the first pressing door 7 and the second pressing door 8 on two different side walls, flexibility is negative
Press operation cabin 2 includes nacelle and detachable support frame, and detachable support frame is used to support nacelle, and nacelle is fexible film cabin
Body, nacelle are connected with forms air-tightness, and after opening the second pressing door 8, forms inside nacelle with connecting；Blasting high-efficiency filter 17
It is arranged at outside nacelle, and the gas outlet of blasting high-efficiency filter 17 inside nacelle with connecting；Level-one air draft high efficiency particulate air filter 18 is set
It is placed in outside nacelle, and the air inlet of level-one air draft high efficiency particulate air filter 18 inside nacelle with connecting；Two level air draft effective filter
20 are arranged at outside nacelle, including two level air draft high efficiency particulate air filter 34 and exhaust blower 35, and two level air draft high efficiency particulate air filter 34 into
Gas port is connected with the gas outlet of level-one air draft high efficiency particulate air filter 18, gas outlet and the exhaust blower 35 of two level air draft high efficiency particulate air filter 34
Connection.
Bio-safety isolating device provided by the invention can be folded storage and rapid deployment；Flexible negative-pressure operation cabin
Nacelle is made of fexible film, has gathering property；During gathering, detachable support frame is pulled down, can be by flexible negative pressure
Operational window compression is collapsed.Bio-safety isolating device provided by the invention, possesses high protection level.Air-tightness pass-through box 1, flexibility
Structure and the accessory equipment in negative-pressure operation cabin 2 use gas-tight design, overall to have good mechanical isolation performance；Normal operation
State, nacelle are equipped with exhaust outlet and air inlet 14, and nacelle is connected by exhaust outlet level-one air draft high efficiency particulate air filter 18, and nacelle is led to
Cross air inlet 14 to be connected with blasting high-efficiency filter 17, and do not set pressure fan between air inlet 14 and blasting high-efficiency filter 17,
An exhaust blower 35 is only connected with after two level air draft high efficiency particulate air filter 34, under the swabbing action of exhaust blower 35, air is by sending
Resistance can be produced during wind high efficiency particulate air filter 17, so as to form in nacelle the negative pressure outside with respect to nacelle, air-flow can just enter from out of my cabin
In cabin.
Bio-safety isolating device provided by the invention employs level-one air draft high efficiency particulate air filter 18 and two level air draft is efficient
Filtration apparatus 20 carries out two-stage to discharge air and efficiently filters so that the gas that two level air draft effective filter 20 is discharged is several
Harmful substance is free of, can directly be thrown into interior, certainly, also may be selected gas being thrown into outdoor.The efficient mistake of level-one air draft
Filter 18 and two level air draft effective filter 20 are respectively positioned on outside nacelle, and are carried out with the gas inside exhaust blower suction nacelle
Filtering, since level-one air draft high efficiency particulate air filter 18 and two level air draft high efficiency particulate air filter 34 equally can produce resistance to air flow,
So the pipeline and connection two level air draft of connection level-one air draft high efficiency particulate air filter 18 and two level air draft high efficiency particulate air filter 34 are efficient
Filter 34 in the pipeline of exhaust blower 35 with can form the negative pressure outside to nacelle so that the gas inside nacelle can only pass through cabin
Exhaust outlet on body is sequentially entered to being filtered in level-one air draft high efficiency particulate air filter 18 and two level air draft high efficiency particulate air filter 34, most
After discharge, without in the junction of nacelle and level-one air draft high efficiency particulate air filter 18 or level-one air draft high efficiency particulate air filter 18 and two level
The junction of air draft high efficiency particulate air filter 34 forms leakage, and security performance is more preferable.
Air-tightness pass-through box 1 is mainly used for transmitting the flexible negative-pressure operation cabin 2 of article disengaging, prevents flexible negative-pressure operation cabin 2
Interior environment is directly connected with extravehicular environment, and air-tightness pass-through box 1 can use rigid plastics material, as Asia make every effort to overcome plate, PVC board,
The transparent plastics such as PC plate, can also set transparent form or forms in air-tightness pass-through box 1, be operated easy to personnel, and air-tightness passes
Pass 1 bottom mounting bracket 6 of window.Flexible negative-pressure operation cabin 2 is negative pressure, more effectively avoids the leakage of harmful substance, improves
The security performance of bio-safety isolating device, blasting high-efficiency filter 18 are filtered to entering to the gas inside nacelle, are protected
It is not contaminated to demonstrate,prove nacelle internal environment；Nacelle makes such as PVC, TPU using transparent thin-film material.
As shown in Fig. 2, forms, which are provided with the side wall of the second pressing door 8, is connected with first flange 4, nacelle passes through one second
Flange 5 is connected with 4 air-tightness of first flange, and first flange 4 is equipped with the air inlet 14 connected with nacelle, blasting high-efficiency filter
17 are arranged on the outer top surface of forms and are connected by air inlet pipeline with air inlet 14.First pressing door 7 and the second pressing door 8 divide
Not by 9 mechanical compaction of mechanical compaction mechanism on the two side of forms.
First flange 4 is equipped with a power supply socket 15 and pressure difference monitoring display device on the side wall inside nacelle
16, power supply socket is 220V power outlets, can be instrument and equipment (such as small-sized heating unit, the whirlpool placed in cofferdam
Revolve the instrument that instrument etc. is used for microorganism detection) power supply is provided；Pressure difference monitoring display device 16 is used to monitor and show in nacelle
Portion's pressure, experimental implementation person can pass through the registration of nacelle Real Time Observation pressure difference monitoring display device 16, to understand inside nacelle
Pressure condition；A high efficiency particulate air filter 11 and an electric appliance control box 12 are provided with the outer top surface of forms, high efficiency particulate air filter 11 connects
Inside logical forms and air, forms are internally provided with ultraviolet lamp 10, power supply socket 15, pressure difference monitoring display device 16 and purple
Outer lamp 10 is electrically connected with electric appliance control box 12, and electric appliance control box 12 is equipped with ultraviolet violet light switch button 13, electric appliance control box 12
It is electrically connected with external power supply, electric appliance control box 12 is connected with 220V home communication power supplys in the present embodiment.
When closed, the pressure inside forms can become larger, the height set on forms for first pressing door 7 or the second pressing door 8
Filter 11 is imitated, when forms internal pressure becomes larger, can be realized outside the partial air extrusion forms in forms and air-tightness is passed
The pressure release of window 1 is passed, and the gas of discharge is filtered；High efficiency particulate air filter 11 in the present embodiment, is set on forms
One blow vent, and at blow vent install a high efficiency particulate air filter 11, realize to discharge air-tightness pass-through box 1 outside gas into
Row filtering, prevents pathogenic microorganism from leaking to outside forms and pollutes external environment.Ultraviolet lamp 10 inside forms, for being transferred to gas
Article in close property pass-through box 1 carries out ultraviolet sterilization, disinfection.
Air-tightness pass-through box 1 sets two sects --- the first pressing door 7 and the second pressing door 8, the first pressing door 7 and second
Pressing door 8 mainly serves for ensuring the overall tightness of air-tightness pass-through box 1, and can realize and article safely is passed through air-tightness
Pass-through box 1 is passed in flexible negative-pressure operation cabin 2 or safely spreads out of article in flexible 2 cabin of negative-pressure operation cabin.
Concrete operation method is：
When needing to place an article within to flexible negative-pressure operation cabin 2：The first pressing door 7 is first opened, then puts required article
Enter to forms, close the first pressing door 7, open the second pressing door 8 by the gloves on operating surface 36 and take out in forms
In article to flexible negative-pressure operation cabin 2, the second pressing door 8 is then shut off, the ultraviolet lamp 10 inside forms is opened, to forms
Internal air is sterilized, sterilized.When needing to take out article from flexible negative-pressure operation cabin 2：First by operating surface 36
Gloves open and the second pressing door 8 and the article be put into forms, close the second pressing door 8, open ultraviolet lamp 1 to transmitting
Article and air in forms are sterilized, sterilized, and are then opened the first pressing door 7, are taken out the article.
Two level air draft effective filter 20 further includes a pressure difference control device and storage battery, and pressure difference control device includes pressure
Gap sensor and control system, are provided with an instrument filter 23 in nacelle, differential pressure pickup passes through pipeline and instrument filter
23 gas outlet connection, differential pressure pickup are electrically connected with control system, and control system is electrically connected with exhaust blower 35, storage battery and control
System processed and exhaust blower 35 are electrically connected, and storage battery is electrically connected with external power supply.
Negative pressure condition inside the enough nacelles of monitoring in real time of differential pressure pickup, and can be by the pressure inside the nacelle collected
Control system is transmitted to, when the nacelle internal pressure that differential pressure pickup monitors is higher than default pressure, control system control
Exhaust blower 35 improves air quantity to ensure the negative regulation inside nacelle.Such as, when the film of nacelle occurs under breakage, outside nacelle
Air can be entered in nacelle from breakage, since the air drag of breakage is very low, far below blasting high-efficiency filter 17
Resistance, so that large quantity of air enters from breakage, and reduces the air capacity entered by blasting high-efficiency filter 17 in cabin,
Negative pressure value in cabin is caused to reduce, at this time, to reach the setting value of pressure difference, two pole air draft effective filters 20 are controlled by pressure difference
Device can improve the power of exhaust blower 35 automatically so as to increase exhaust air rate, make breakage air keep being inwardly directed flowing, effectively
Poisonous and harmful substance is by leaking into flexible 2 external environment condition of negative-pressure operation cabin in the flexible negative-pressure operation cabin 2 of reduction at breakage of thin film applied
Risk；Differential pressure pickup is arranged on inside two level exhaust-air filter 20, differential pressure pickup by inside tracheae and nacelle into
Row connection, and an instrument filter 23 is connected with the end being passed through to nacelle of differential pressure pickup, with to entering to pressure
The air of gap sensor interface is filtered, and avoids the pathogenic microorganism aerosol inside nacelle from entering in differential pressure pickup,
Protect differential pressure pickup from the pollution of gas in nacelle.
As shown in figures 4-6, multiple glove holes, each glove hole are additionally provided with the operating surface 36 in flexible negative-pressure operation cabin 2
Hermetic seal is connected with a gloves, and gloves include oversleeve 28, cuff ring 29 and glove bulk 30, each glove hole and an oversleeve
28 one end hermetic seal connection, the other end of oversleeve 28 are connected with the inner of cuff ring 29, and the outer end of cuff ring 29 stretches to set
In sleeve 28, multiple card slots are provided with each 29 outer wall of cuff ring, glove bulk 30 is fixed on a card by elastic rubber ring
In groove.
Said structure sets the glove bulk 30 that can conveniently realize that online replacement is damaged on the outside of nacelle, has good behaviour
Make convenience, the glove bulk 30 in the present embodiment is the rubber operating gloves body of chemically-resistant disinfectant corrosion, multiple card slots
Including at least the first card slot 31 and the second card slot 32；During online replacement glove bulk 30, glove bulk 30 is dragged to outside nacelle, will
Elastic rubber ring is removed and retreats to damaged glove bulk mouth in the first card slot 31, to ensure damaged glove bulk 30 during being somebody's turn to do
Do not slide, then by new glove bulk 30, reversely set is on cuff ring 29, using elastic rubber ring by new glove bulk 30
It is fixed in the second card slot 32, then, removes damaged glove bulk 30 inside nacelle, glove bulk 30 is replaced and finished, rubber
Rubber gloves body is fixed on by elastic rubber ring in the second card slot 32 that cuff ring 29 is located on the outside of nacelle.
Oversleeve 28 is fixed in the inner card slot of cuff ring 29 by elastic rubber ring, but not limited to this kind connection mode,
The end of oversleeve 28 can be also welded and fixed together with cuff ring 29 by heat seal, as long as oversleeve 28 and cuff ring 29 can be realized
Be fixedly connected.
Detachable support frame includes more seamed edge supporting rods 3 and multiple seamed edge fasteners 24, and nacelle is polyhedron, nacelle
Each seamed edge on be both provided with a seamed edge connecting sleeve 25, and operating surface 36 is equipped with one only on each seamed edge of operating surface 36
A seamed edge connecting sleeve 25, is equipped with a seamed edge supporting rod 3, adjacent two seamed edge branch in each seamed edge connecting sleeve 25
Connected between strut 3 by seamed edge fastener 24, operating surface be provided with the outer surface of the operating surface 36 of nacelle and tenses casing 37,
It is transparent casing that operating surface, which tenses casing 37, and operating surface tenses in casing 37 and is equipped with a tension rope 26, the both ends of tension rope 26
It is fixedly connected with the seamed edge supporting rod 3 at 36 both ends of operating surface.
Set using the above structure so that bio-safety isolating device provided by the invention can be folded storage and quick
Expansion.The device nacelle is made of fexible film, foldable, and branch is fixed by detachable support frame outside nacelle
Support, detachable support frame are lightweight support frame and detachable, and flexible negative-pressure operation cabin has gathering property., will during gathering
Blasting high-efficiency filter 17, level-one air draft high efficiency particulate air filter 18 and two level air draft effective filter 20 are removed, will be exterior removable
Unload support frame to pull down, gathering can be compressed in flexible negative-pressure operation cabin 2, by flexible negative-pressure operation cabin 2 and air-tightness pass-through box 1
Stored together.The tension rope 26 set on operating surface 36 avoids operating surface 36 and occurs due to the pressure differential inside and outside nacelle
Excessive depression, and will not stop the sight of operator, easy to the progress of experiment.
Operating surface 36 tilts backwards setting from the bottom to top, reduces obstacle, and personnel easy to operation carry out before operating surface 36
Operation.
Detachable support frame further includes side wall support bar 38 and side wall fastener 41, and nacelle is in the side opposite with operating surface
At least one side wall is equipped with the outer surface of wall and on the outer top surface of nacelle and tenses casing 39, each side wall tenses casing 39
A side wall support bar 38 is inside equipped with, the both ends of every side wall support bar 38 pass through side wall fastener 41 and the side arm supports bar
Seamed edge supporting rod 3 on 38 surfaces supported connects.
In said structure, side wall support bar 38 and seamed edge supporting rod 3 are hard pipe fitting, due to being negative pressure shape inside nacelle
State, side wall support bar 38 can be supported the side wall of nacelle, avoid side wall from occurring due to the pressure differential inside and outside nacelle
The depression of degree, so as to avoid the reduction of operating space inside nacelle.
Polylith hard operation tablet 27 is equipped with nacelle inner bottom surface, level-one air draft high efficiency particulate air filter 18 and two level air draft are high
Effect filtration apparatus 20 is installed on the top of nacelle by a support plate 40 respectively, each support plate 40 with outside nacelle on top surface
Two adjacent side wall support bars 38 and/or seamed edge supporting rod 3 are fixedly connected, connection level-one air draft high efficiency particulate air filter 18 and two level
19 end of exhaust pipeline of air draft high efficiency particulate air filter 34 is equipped with the first sampling of aerosol mouth 21, connects two level air draft high efficiency particulate air filter
34 are equipped with the second sampling of aerosol mouth 33 with the pipeline of exhaust blower 35.
The polylith hard operation tablet 27 that nacelle bottom upper strata is equipped with, for preventing because negative pressure causes flexible negative-pressure operation
2 operating table surface of cabin is raised uneven and influences operation.
The support plate 40 set at the top of nacelle can support level-one air draft high efficiency particulate air filter 18 and two level air draft high efficiency filter
Device 20.Level-one air draft high efficiency particulate air filter 18 and two level air draft effective filter 20 can carry out leak detection in situ, use air
Sampling apparatus, e.g., laser particle counter, tests the particle at the 14 and first sampling of aerosol mouth 21 of air inlet of nacelle respectively
Thing concentration, by the filter efficiency of the concentration ratio first order calculation air draft high efficiency particulate air filter 18 at two, when filter efficiency is less than normal
Think that level-one air draft high efficiency particulate air filter 18 leaks during value；Tested using air sampling rig at the second sampling of aerosol mouth 33
Particle concentration, it is efficient to calculate two level air draft by concentration ratio at the first sampling of aerosol mouth 21 and the second sampling of aerosol mouth 33
The filter efficiency of filter 34, thinks that two level air draft high efficiency particulate air filter 34 is leaked when filter efficiency is less than normal value；First
It is closing under 21 and second sampling of aerosol mouth of sampling of aerosol mouth, 33 normal condition, only just by its dozen when sampling
Open.
After the completion of experiment, a sterilizing equipment decontaminating apparatus 42 also can be used to disappear bio-safety isolating device provided by the invention
Poison, sterilizing equipment decontaminating apparatus 42 can carry out disinfection the gas in bio-safety isolating device or steam.
The gas outlet of two level air draft effective filter 20 can be used as gas with the air inlet of blasting high-efficiency filter 17
Sterilization interface, can use two methods to arrange nacelle, blasting high-efficiency filter 17, level-one air draft high efficiency particulate air filter 18 and two level
Wind effective filter 20 carries out disinfection.Disinfection process is as follows：
1) can be by sterilizing connecting line 43 by the gas outlet of two level air draft effective filter 30 and blasting high-efficiency mistake
The air inlet of filter 17, which is attached, makes bio-safety isolating device form closed-loop gas disinfection loop with sterilizing equipment decontaminating apparatus 42, will disappear
Malicious equipment 42, which is placed into inside nacelle, occurs disinfectant, opens the exhaust blower 35 inside two level air draft effective filter 20, makes
Disinfectant continues to penetrate level-one air draft high efficiency particulate air filter 18, two level air draft effective filter 20 and blasting high-efficiency filter successively
17, integrally carry out disinfection to bio-safety isolating device, as shown in Figure 7.
2) can be by sterilizing connecting line 42 by the gas outlet of two level air draft effective filter 20 and blasting high-efficiency mistake
The air inlet of filter 17 is respectively connected to the air inlet and exhaust outlet of sterilizing equipment decontaminating apparatus 42, bio-safety isolating device is set with disinfection
Standby 42 form gas (vapour) body disinfection loop, to carry out disinfection to bio-safety isolating device, as shown in Figure 8.
Specific case is applied in the present invention to be set forth the principle of the present invention and embodiment, above example
Illustrate to be only intended to help the method and its core concept for understanding the present invention；Meanwhile for those of ordinary skill in the art, according to
According to the thought of the present invention, in specific embodiments and applications there will be changes.In conclusion this specification content
It should not be construed as limiting the invention.
Claims (10)
- A kind of 1. bio-safety isolating device, it is characterised in that：Including：Air-tightness pass-through box, including forms, the forms in be respectively equipped with two different side walls the first pressing door and second pressure Tight door；Flexible negative-pressure operation cabin, including nacelle and detachable support frame, the detachable support frame are used to support the cabin Body, the nacelle are fexible film nacelle, and the nacelle is connected with the forms air-tightness, after opening second pressing door, The forms inside the nacelle with connecting；Blasting high-efficiency filter, the blasting high-efficiency filter are arranged at outside the nacelle, and the blasting high-efficiency filter Gas outlet inside the nacelle with connecting；Level-one air draft high efficiency particulate air filter, the level-one air draft high efficiency particulate air filter are arranged at outside the nacelle, and the level-one air draft The air inlet of high efficiency particulate air filter inside the nacelle with connecting；AndTwo level air draft effective filter, the two level air draft effective filter are arranged at outside the nacelle, including two level row Wind high efficiency particulate air filter and exhaust blower, and the air inlet of the two level air draft high efficiency particulate air filter and the level-one air draft high efficiency particulate air filter Gas outlet connection, the gas outlet of the two level air draft high efficiency particulate air filter is connected with the exhaust blower.
- 2. bio-safety isolating device according to claim 1, it is characterised in that：The forms are provided with second pressure First flange is connected with the side wall of tight door, the nacelle is connected by second flange with the first flange air-tightness, described First flange is equipped with the air inlet connected with the nacelle, and the blasting high-efficiency filter is arranged at the outer top surface of the forms Above and by air inlet pipeline it is connected with the air inlet.
- 3. bio-safety isolating device according to claim 2, it is characterised in that：The first flange is in the nacelle The side wall in portion is equipped with a power supply socket and pressure difference monitoring display device, and the pressure difference monitoring display device is used to monitor And show the nacelle internal pressure, a high efficiency particulate air filter and an electric appliance control box are provided with the outer top surface of the forms, The high efficiency particulate air filter connects inside the forms and air, the forms are internally provided with ultraviolet lamp, and the power supply is inserted Seat, the pressure difference monitoring display device and the ultraviolet lamp is electrically connected with the electric appliance control box, the electric appliance control box and External power supply is electrically connected.
- 4. bio-safety isolating device according to claim 1, it is characterised in that：The two level air draft effective filter A pressure difference control device and storage battery are further included, the pressure difference control device includes differential pressure pickup and control system, the cabin An instrument filter is provided with vivo, the differential pressure pickup is connected by pipeline with the gas outlet of the instrument filter, institute State differential pressure pickup to be electrically connected with the control system, the control system and the air draft mechatronics, the storage battery with The control system and the air draft mechatronics, the storage battery are electrically connected with external power supply.
- 5. bio-safety isolating device according to claim 1, it is characterised in that：The operation in the flexibility negative-pressure operation cabin Multiple glove holes are additionally provided with face, each glove hole hermetic seal is connected with a gloves, and the gloves include oversleeve, sleeve Choma and glove bulk, each glove hole are connected with one end hermetic seal of an oversleeve, the other end of the oversleeve It is connected with the inner of the cuff ring, the outer end of the cuff ring is stretched in the oversleeve, on each cuff ring outer wall Multiple card slots are provided with, the glove bulk is fixed in a card slot by elastic rubber ring.
- 6. bio-safety isolating device according to claim 5, it is characterised in that：The oversleeve passes through the elastic rubber Circle is fixed in the card slot of described cuff ring the inner.
- 7. bio-safety isolating device according to claim 1, it is characterised in that：The detachable support frame includes more Root seamed edge supporting rod and multiple seamed edge fasteners, the nacelle are polyhedron, and one is both provided with each seamed edge of the nacelle Seamed edge connecting sleeve, and operating surface is equipped with a seamed edge connecting sleeve only on each seamed edge of operating surface, it is each described A seamed edge supporting rod is equipped with seamed edge connecting sleeve, by described between adjacent two seamed edge supporting rods Seamed edge fastener connects, and operating surface is provided with the outer surface of the operating surface of the nacelle and tenses casing, the operating surface tenses Casing is transparent casing, and the operating surface tenses and a tension rope is equipped with casing, both ends and the operating surface two of the tension rope The seamed edge supporting rod at end is fixedly connected；The operating surface tilts backwards setting from the bottom to top.
- 8. bio-safety isolating device according to claim 7, it is characterised in that：The detachable support frame further includes Side wall support bar and side wall fastener, the nacelle is on the outer surface of the side wall opposite with the operating surface and the nacelle Outer top surface on be equipped with least one side wall and tense casing, each side wall, which is tensed in casing, is equipped with a side wall Supporting rod, on the surface that the both ends of the side wall support bar are supported by the side wall fastener and the side arm supports bar The seamed edge supporting rod connection.
- 9. bio-safety isolating device according to claim 8, it is characterised in that：It is equipped with the nacelle inner bottom surface more Block hard operates tablet, and the level-one air draft high efficiency particulate air filter and the two level air draft effective filter pass through a branch respectively Fagging is installed on the top of the nacelle, each support plate with two adjacent side walls on top surface outside the nacelle Supporting rod and/or the seamed edge supporting rod are fixedly connected.
- 10. bio-safety isolating device according to claim 1, it is characterised in that：Connect the efficient mistake of level-one air draft The exhaust pipeline end of filter and the two level air draft high efficiency particulate air filter is equipped with the first sampling of aerosol mouth, to connect air sampling Device realizes the leak detection in situ of the level-one air draft high efficiency particulate air filter, connects the two level air draft high efficiency particulate air filter and the air draft The pipeline of machine is equipped with the second sampling of aerosol mouth, and the two level air draft high efficiency particulate air filter is realized to connect air sampling rig Original position leak detection；Further include a sterilizing equipment decontaminating apparatus, the air outlet of the two level air draft effective filter and the blasting high-efficiency filter into Air port is connected by sterilizing connecting line, and the sterilizing equipment decontaminating apparatus is arranged on the disinfection connecting line or in the nacelle.
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| CN201711407717.8A CN107930704A (en) | 2017-12-22 | 2017-12-22 | A kind of bio-safety isolating device |
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| CN201711407717.8A CN107930704A (en) | 2017-12-22 | 2017-12-22 | A kind of bio-safety isolating device |
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| CN107930704A true CN107930704A (en) | 2018-04-20 |
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| CN201711407717.8A Pending CN107930704A (en) | 2017-12-22 | 2017-12-22 | A kind of bio-safety isolating device |
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| CN109355187A (en) * | 2018-11-22 | 2019-02-19 | 英诺维尔智能科技（苏州）有限公司 | A kind of frame-type cofferdam system system |
| CN109906947A (en) * | 2019-04-03 | 2019-06-21 | 苏州市冯氏实验动物设备有限公司 | A kind of host of IVC experimental animal case, IVC experimental animal case and method |
| CN109906948A (en) * | 2019-04-03 | 2019-06-21 | 苏州市冯氏实验动物设备有限公司 | A kind of the internal air circulation system and control method of IVC experimental animal case |
| CN110083183A (en) * | 2019-04-25 | 2019-08-02 | 中国科学院武汉病毒研究所 | A kind of biosecurity laboratory chemistry shower cabinet pressure regulating method and system |
| CN110216719A (en) * | 2019-07-05 | 2019-09-10 | 中国建筑科学研究院有限公司 | A protector for biological experiments for biosafety laboratory |
| CN110468046A (en) * | 2019-07-02 | 2019-11-19 | 英诺维尔智能科技（苏州）有限公司 | A kind of isolator warehouse structure |
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| CN112914901A (en) * | 2021-01-25 | 2021-06-08 | 军事科学院系统工程研究院卫勤保障技术研究所 | Negative pressure isolation system for aerial transportation infectious patient |
| CN114838427A (en) * | 2022-05-11 | 2022-08-02 | 军事科学院系统工程研究院卫勤保障技术研究所 | Aerosol exposes isolating device |
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| CN112914901A (en) * | 2021-01-25 | 2021-06-08 | 军事科学院系统工程研究院卫勤保障技术研究所 | Negative pressure isolation system for aerial transportation infectious patient |
| CN114838427A (en) * | 2022-05-11 | 2022-08-02 | 军事科学院系统工程研究院卫勤保障技术研究所 | Aerosol exposes isolating device |
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Application publication date: 20180420 |