CN212187892U - System for utilize separation technique of simulated mobile chromatography to produce pluralism oligosaccharide - Google Patents
System for utilize separation technique of simulated mobile chromatography to produce pluralism oligosaccharide Download PDFInfo
- Publication number
- CN212187892U CN212187892U CN202020699929.9U CN202020699929U CN212187892U CN 212187892 U CN212187892 U CN 212187892U CN 202020699929 U CN202020699929 U CN 202020699929U CN 212187892 U CN212187892 U CN 212187892U
- Authority
- CN
- China
- Prior art keywords
- simulated moving
- moving bed
- concentrator
- ion exchanger
- outlet
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Images
Landscapes
- Saccharide Compounds (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
Abstract
The utility model belongs to the technical field of the oligosaccharide production, specifically be a system for utilize simulation mobile chromatography separation technology to produce pluralism oligosaccharide. The simulated moving bed device comprises a simulated moving bed I, wherein an extracting solution outlet of the simulated moving bed I is connected with an ion exchanger I, a liquid outlet of the ion exchanger I is connected with a concentrator I, a concentrated solution outlet of the concentrator I is connected with a spray dryer I, and the spray dryer I is connected with a product storage tank I; a raffinate outlet of the simulated moving bed is connected with an ion exchanger II, a liquid outlet of the ion exchanger II is connected with a concentrator II, and a concentrated solution outlet of the concentrator II is connected with an F55 high fructose syrup storage tank. Utilize the utility model discloses a system can obtain the pluralism isomaltose hypgather product to because do not use the yeast fermentation, consequently the product does not have the yeast peculiar smell, and the taste is better.
Description
Technical Field
The utility model belongs to the technical field of the production of low polymer iso-sugar, specifically be a system for utilize simulation to remove chromatographic fractionation technique production pluralism oligose.
Background
The oligosaccharide is mainly low-degree polymeric sugar formed by connecting 2-10 monosaccharides through glycosidic bonds, comprises natural products or synthesized by biochemical reaction, and is divided into functional oligosaccharide and common oligosaccharide. The oligosaccharide with physiological function regulating function is functional oligosaccharide, can be digested and absorbed in gastrointestinal tract, and has no physiological function of proliferating Bacillus bifidus.
The isomaltooligosaccharide weili is called as IMO for short, and is also called as prebiotics, and has a proliferation function on beneficial bacteria in intestinal tracts, can improve the efficacy of a human digestive system, has been widely added into the aspects of foods, health-care products and the like, and has great market demand potential. At present, the specifications of domestic commercial IMO products mainly comprise two types: IMO-500 type (IG2+ P + IG3+ Gn is more than or equal to 50 percent) and IMO-900 type (IG2+ P + IG3+ Gn is more than or equal to 90 percent).
The traditional isomaltose hypgather production process is that starch is used as raw material, the high temperature resistant a-amylase is liquefied, then the alpha-amylase or beta-amylase is saccharified, and simultaneously, the alpha-transglucosidase is used for saccharification and glucoside conversion to produce IMO500 type syrup, and the IMO500 type syrup can be directly sold or spray dried to be powder. The yeast fermentation method is used for producing IMO-900 type products, is a process route taken by many enterprises at the present stage, and has the main principle that yeast is used for removing glucose and part of maltose in IMO-500 liquid, and isomaltose with a-1, 6 glycosidic bonds and the like cannot be fermented by yeast, so that the aim of improving the isomaltooligosaccharide total sugar in syrup is fulfilled. However, the current production system can only obtain one type of IMO900 product, and a system capable of obtaining diversified oligosaccharides is needed.
SUMMERY OF THE UTILITY MODEL
For the production system product singleness that solves prior art, the product taste is not good, problem such as the cost is on the high side, the utility model provides an utilize simulation to move the system of chromatographic fractionation technique production pluralism oligosaccharide, utilize this system can obtain the pluralism oligosaccharide product to owing to not using the yeast fermentation, consequently the product does not have the yeast peculiar smell, and the taste is better.
The technical scheme of the utility model is that:
a system for producing diversified oligosaccharides by using a simulated mobile chromatography separation technology comprises a simulated moving bed I, wherein an extracting solution outlet of the simulated moving bed I is connected with an ion exchanger I, a liquid outlet of the ion exchanger I is connected with a concentrator I, a concentrated solution outlet of the concentrator I is connected with a spray dryer I, and the spray dryer I is connected with a product storage tank I;
a raffinate outlet of the simulated moving bed is connected with an ion exchanger II, a liquid outlet of the ion exchanger II is connected with a concentrator II, and a concentrated solution outlet of the concentrator II is connected with an F55 high fructose corn syrup storage tank;
the concentrated solution outlet of the concentrator I is also connected with a simulated moving bed II, the extracting solution outlet of the simulated moving bed II is connected with an ion exchanger III, the liquid outlet of the ion exchanger III is connected with a concentrator III, the concentrated solution outlet of the concentrator III is connected with a spray dryer III, and the spray dryer III is connected with a product storage tank III; and raffinate outlet liquid of the simulated moving bed II is connected with an ion exchanger IV, a liquid outlet of the ion exchanger IV is connected with a concentrator IV, a concentrated liquid outlet of the concentrator IV is connected with a spray dryer IV, and the spray dryer IV is connected with a product storage tank IV.
More preferably, the number of chromatographic columns of the simulated moving bed I is 4-6, and Ca-type cation exchange resin is adopted as the separation resin.
Furthermore, the particle size of the ion exchange resin of the simulated moving bed I is 0.20-0.40 mm, and the crosslinking degree of the resin is 4-8% (DVB).
Furthermore, the simulated moving bed II is a sequential simulated moving bed, and K-type cation exchange resin is used as the separation resin.
Furthermore, the particle size of the ion exchange resin of the simulated moving bed II is 0.20-0.40 mm, and the crosslinking degree of the resin is 4-8% (DVB).
The utility model has the advantages that,
the utility model discloses an utilize system of simulation mobile chromatography separation technique production pluralism oligosaccharide through the structure setting, has obtained the system of pluralism oligosaccharide to utilize this system because do not use the yeast fermentation, consequently the product does not have the yeast peculiar smell, and the taste is better.
Products obtained through the system can be sold as novel high-end products, and the economic benefits of enterprises are greatly increased.
The utility model discloses a sequential simulated moving bed chromatogram can less chromatographic column reach or exceed the separation effect of a plurality of chromatographic columns, and the investment of adopting few post to chromatographic separation's industrialization device is little, separation performance is good, and the control system precision is high, easily steady operation and control.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, and it is obvious for those skilled in the art that other drawings can be obtained according to the drawings without creative efforts.
Fig. 1 is a schematic structural diagram of the present invention.
Wherein, 1-a raffinate outlet of a simulated moving bed I, 11-a raffinate outlet of the simulated moving bed I, 12-an extract outlet of the simulated moving bed I, 2-an ion exchanger II, 21-an ion exchanger III, 22-a concentrator III, 23-a spray dryer III, 24-a product storage tank III, a liquid outlet of a 25-the ion exchanger II, 3-a concentrator II, 31-an ion exchanger IV, 32-a concentrator IV, 33-a spray dryer IV, 34-a product storage tank IV, a concentrated liquid outlet of a 35-the concentrator II, 4-F55 a high fructose syrup storage tank 4, 5-an ion exchanger I, a liquid outlet of a 55-the ion exchanger I, a concentrated liquid outlet of a 6-a concentrator I, 65-a concentrator I, a 7-the spray dryer I, 8-a product storage tank I, 9-simulated moving bed II, 91-an extract outlet of the simulated moving bed II, and 92-a raffinate outlet of the simulated moving bed II.
Detailed Description
In order to make the technical solutions in the present invention better understood, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, but not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative efforts shall belong to the protection scope of the present invention.
Example 1
With reference to fig. 1, it can be seen that the utility model discloses a system for utilize simulated moving chromatography separation technique to produce pluralism oligosaccharide, including simulated moving bed I1, I chromatographic column quantity of simulated moving bed is 6 posts, adopts Ca type resin as the separation resin, and the particle diameter of the ion exchange resin of simulated moving bed I is 0.3 millimeter, and the degree of crosslinking of resin is 6% (DVB).
And a raffinate outlet 11 of the simulated moving bed is connected with an ion exchanger II 2, a liquid outlet 25 of the ion exchanger II is connected with a concentrator II 3, and a concentrated solution outlet 35 of the concentrator II is connected with an F55 high fructose syrup storage tank 4.
The concentrated solution outlet 65 of the concentrator I is also connected with a simulated moving bed II 9, the simulated moving bed II is a sequential simulated moving bed, K-type cation exchange resin is used as separation resin, the particle size of the ion exchange resin of the simulated moving bed II is 0.20 mm, and the crosslinking degree of the resin is 8% (DVB).
An extracting solution outlet 91 of the simulated moving bed II is connected with an ion exchanger III 21, a liquid outlet of the ion exchanger III is connected with a concentrator III 22, a concentrated solution outlet of the concentrator III is connected with a spray dryer III 23, and the spray dryer III 23 is connected with a product storage tank III 24; and a raffinate outlet 92 of the simulated moving bed II is connected with an ion exchanger IV 31, a liquid outlet of the ion exchanger IV is connected with a concentrator IV 32, a concentrated solution outlet of the concentrator IV is connected with a spray dryer IV 33, and the spray dryer IV is connected with a product storage tank IV 34.
Although the present invention has been described in detail by referring to the drawings in conjunction with the preferred embodiments, the present invention is not limited thereto. Various equivalent modifications or substitutions can be made on the embodiments of the present invention by those skilled in the art without departing from the spirit and substance of the present invention, and these modifications or substitutions are intended to be within the scope of the present invention/any person skilled in the art can easily conceive of changes or substitutions within the technical scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the claims.
Claims (5)
1. A system for producing diversified oligosaccharides by using a simulated mobile chromatography separation technology is characterized by comprising a simulated moving bed I, wherein an extracting solution outlet of the simulated moving bed I is connected with an ion exchanger I, a liquid outlet of the ion exchanger I is connected with a concentrator I, a concentrated solution outlet of the concentrator I is connected with a spray dryer I, and the spray dryer I is connected with a product storage tank I;
a raffinate outlet of the simulated moving bed is connected with an ion exchanger II, a liquid outlet of the ion exchanger II is connected with a concentrator II, and a concentrated solution outlet of the concentrator II is connected with an F55 high fructose corn syrup storage tank;
the concentrated solution outlet of the concentrator I is also connected with a simulated moving bed II, the extracting solution outlet of the simulated moving bed II is connected with an ion exchanger III, the liquid outlet of the ion exchanger III is connected with a concentrator III, the concentrated solution outlet of the concentrator III is connected with a spray dryer III, and the spray dryer III is connected with a product storage tank III; and raffinate outlet liquid of the simulated moving bed II is connected with an ion exchanger IV, a liquid outlet of the ion exchanger IV is connected with a concentrator IV, a concentrated liquid outlet of the concentrator IV is connected with a spray dryer IV, and the spray dryer IV is connected with a product storage tank IV.
2. The system for producing diversified oligosaccharides through simulated moving chromatography according to claim 1, wherein the number of the chromatographic columns of the simulated moving bed I is 4-6, and Ca-type resin is used as the separation resin.
3. The system for producing diversified oligosaccharides through simulated moving chromatography according to claim 2, wherein the ion exchange resin of the simulated moving bed i has a particle size of 0.20-0.40 mm, and the degree of cross-linking of the resin is 4-8% DVB.
4. The system for producing diversified oligosaccharides using the simulated moving chromatography as claimed in claim 1, wherein the simulated moving bed ii is a sequential simulated moving bed, and a type K cation exchange resin is used as the separation resin.
5. The system for producing diversified oligosaccharides through simulated moving chromatography according to claim 4, wherein the particle size of the ion exchange resin of the simulated moving bed II is 0.20-0.40 mm, and the degree of cross-linking of the resin is 4-8% DVB.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202020699929.9U CN212187892U (en) | 2020-04-30 | 2020-04-30 | System for utilize separation technique of simulated mobile chromatography to produce pluralism oligosaccharide |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202020699929.9U CN212187892U (en) | 2020-04-30 | 2020-04-30 | System for utilize separation technique of simulated mobile chromatography to produce pluralism oligosaccharide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN212187892U true CN212187892U (en) | 2020-12-22 |
Family
ID=73831705
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202020699929.9U Active CN212187892U (en) | 2020-04-30 | 2020-04-30 | System for utilize separation technique of simulated mobile chromatography to produce pluralism oligosaccharide |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN212187892U (en) |
-
2020
- 2020-04-30 CN CN202020699929.9U patent/CN212187892U/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Nobre et al. | New trends and technological challenges in the industrial production and purification of fructo-oligosaccharides | |
| Singh et al. | Biocatalytic strategies for the production of high fructose syrup from inulin | |
| CN106636256B (en) | Xylo-oligosaccharide with low polymerization degree and preparation method and application thereof | |
| CN104152512B (en) | Preparation method of isomaltooligosacharide | |
| Kovács et al. | Recent developments in manufacturing oligosaccharides with prebiotic functions | |
| Singh et al. | Updates on inulinases: Structural aspects and biotechnological applications | |
| KR102381709B1 (en) | Method of manufacuring dietary fiber | |
| CN104131051B (en) | A kind of preparation method of oligoisomaltose | |
| CN103045701A (en) | High-yield method for co-producing resistant dextrin, beta-cyclodextrin and F42 HFCS (high fructose corn syrup) | |
| CN108004284B (en) | Preparation method of xylooligosaccharide with polymerization degree of 2-6 | |
| CN103484512B (en) | Method for producing high-functional-trisaccharide-content isomaltooligosaccharide by using immobilized cells | |
| CN104171800A (en) | Isomaltooligosacharide-fructooligosaccharide composite particle and preparation method thereof | |
| CN103952452A (en) | Method for preparing environment-friendly high-purity isomaltooligosaccharide | |
| CN104418919A (en) | Production method for mycose | |
| CN101597628A (en) | The method of preparing xylo-oligosaccharide by corn husk enzymatic hydrolysis | |
| Li et al. | Production, separation, and characterization of high-purity xylobiose from enzymatic hydrolysis of alkaline oxidation pretreated sugarcane bagasse | |
| CN212187892U (en) | System for utilize separation technique of simulated mobile chromatography to produce pluralism oligosaccharide | |
| CN101438782B (en) | Moisture-keeping syrup and preparation method thereof | |
| CN103695501A (en) | Method for producing lactosucrose employing levansucrase | |
| CN108546724A (en) | High-purity oligoisomaltose and preparation method thereof | |
| CN109055461B (en) | Production method of isomaltooligosaccharide | |
| CN103194506A (en) | Method for catalytic production of fructo-oligosaccharides by aspergillus oryzae whole cells | |
| CN112111542B (en) | Preparation method of high-purity isomaltooligosaccharide co-produced resistant dextrin | |
| CN103936878A (en) | Method for purifying isomaltose hypgather by virtue of sequential simulated moving chromatography (SSMB) | |
| CN103937855A (en) | Method for synthesizing isomalto oligosaccharides through fully enzymatic transformation path |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant |