CN212159462U - Online temperature measurement agitating unit - Google Patents

Online temperature measurement agitating unit Download PDF

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Publication number
CN212159462U
CN212159462U CN202020583426.5U CN202020583426U CN212159462U CN 212159462 U CN212159462 U CN 212159462U CN 202020583426 U CN202020583426 U CN 202020583426U CN 212159462 U CN212159462 U CN 212159462U
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China
Prior art keywords
temperature
stirring
temperature measurement
solvent
dissolution
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CN202020583426.5U
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Chinese (zh)
Inventor
寿淼钧
侯海山
单剑宏
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Ningbo Scientz Biotechnology Co ltd
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Ningbo Scientz Biotechnology Co ltd
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Abstract

The utility model discloses an online temperature measurement agitating unit, puddler and temperature element, temperature element seal installation are in the puddler, and temperature element links to each other with a rotation connector, and the rotation connector is used for connection director, reads and exports the temperature value that temperature element measured through the controller. The device simple structure is applicable to the online temperature measurement stirring of medicine inspection class instrument. When the device is applied to a drug dissolution instrument, the bottom end of the stirring rod is always immersed in the solvent in the dissolution experiment process, so that the temperature of the solvent can be monitored in real time, and the authenticity and the real-time property of the temperature data of the solvent in the dissolution experiment are ensured. The device can directly carry out real time monitoring to the menstruum temperature, improves the monitorability and the digitization of menstruum temperature among the degree of dissolving out experimentation by a wide margin, and the menstruum temperature data that obtain more have real-time and validity, more are favorable to the data judgement of degree of dissolving out experiment, and the experimenter of being convenient for carries out the analysis to the experimental result of dissolving out.

Description

Online temperature measurement agitating unit
Technical Field
The utility model relates to a temperature measurement agitating unit specifically is an online temperature measurement agitating unit, is applicable to the online temperature measurement stirring of medicine class instruments such as medicine dissolving-out appearance.
Background
The temperature of the solvent has a critical role during the dissolution test. In the whole (dissolution) stirring experiment process, in order to ensure the reliability of the dissolution experiment, other devices which interfere the dissolution process except the stirring device in the dissolution cup are not needed to be arranged, otherwise, the dissolution result is influenced. When a traditional dissolution instrument is used for performing a dissolution experiment, in order to ensure the accuracy of the experiment, the temperature of the solvent can be fed back only by monitoring the temperature of the water bath, or the temperature of the solvent can be measured for a short time during sampling, so that the temperature of the solvent in the traditional dissolution experiment process is not monitored in real time. Because the dissolution cup is arranged between the solvent and the water bath for isolation, the dissolution cup has certain thermal resistance, and the thermal resistance of all the dissolution cups is inconsistent, the temperature of the water bath is not equal to the temperature of the solvent, namely the real-time temperature of the water bath does not represent the real-time temperature of the solvent. In summary, when the conventional dissolution apparatus performs a dissolution experiment, the sampling of the solvent temperature is performed only during the sampling, and the sampling frequency is limited, which results in insufficient solvent temperature monitoring data; meanwhile, the response time of the temperature probe is slow, so the temperature probe needs to be immersed in the solvent for a certain time during solvent temperature sampling, and the temperature probe is interfered in the time period, thereby influencing the dissolution experiment.
Disclosure of Invention
The utility model aims to solve the technical problem that, not enough to prior art provides an online temperature measurement agitating unit, and the device is applicable to the online temperature measurement stirring of medicine detection class instruments such as the medicine dissolution appearance, and in the degree of dissolution experimentation, the device not only can satisfy traditional stirring demand, can carry out real time monitoring to the menstruum temperature simultaneously to ensure authenticity and the real-time of menstruum temperature data in the degree of dissolution experiment.
The utility model provides a technical scheme that above-mentioned technical problem adopted does: the temperature measuring element is hermetically arranged in the stirring rod, the temperature measuring element is connected with a rotating connector, the rotating connector is used for being connected with a controller, and the temperature value measured by the temperature measuring element is read and output through the controller.
The utility model discloses online temperature measurement agitating unit is applicable to the online temperature measurement stirring of class instrument is examined to the medicine. When applied to a drug dissolution instrument, the device is mainly used for solvent stirring and solvent temperature online measurement in dissolution rate experiments. In the dissolution experiment process, the bottom end of the stirring rod is always immersed in the solvent, so that the temperature of the solvent can be monitored in real time, and the authenticity and the real-time property of the temperature data of the solvent in the dissolution experiment are ensured. The utility model discloses online temperature measurement agitating unit can directly carry out real time monitoring to the menstruum temperature, improves the monitorable nature and the digital voltinism of menstruum temperature in the degree of dissolution experimentation by a wide margin, and the menstruum temperature data that obtain more has real-time and validity, more is favorable to the data judgement of degree of dissolution experiment, and the experimenter of being convenient for carries out the analysis to the experimental result of dissolving out.
Preferably, a hole with an open end is formed in the stirring rod, the temperature measuring element is installed in the hole, a heat-conducting filling medium cladding is filled between the outer surface of the temperature measuring element and the wall of the hole, and the open end of the hole is sealed by a sealing element. The packing medium covering has the effect of heat conduction, can realize simultaneously that temperature element is at the inside fixed of puddler, combines sealing element to seal temperature element encapsulation downthehole, can prevent inside liquid etc. get into the puddler, guarantees the stability and the accuracy of device temperature measurement.
Further, the filling medium cladding is an epoxy resin cladding or a heat-conducting silicone grease cladding, and the sealing element is an epoxy resin sealing element or a heat-conducting silicone grease sealing element. In practical application, the filling medium cladding and the sealing element made of other materials can be adopted.
Preferably, the stirring rod comprises a connecting rod and a stirring head, the stirring head is integrally connected to the bottom end of the connecting rod, and the hole is formed in the connecting rod and reaches the bottom of the stirring head. The utility model discloses when online temperature measurement agitating unit was applied to the class instrument of drug testing, before the use, linked to each other connecting rod and actuating mechanism to will stir first submergence in the menstruum, assembly convenient operation.
Preferably, the rotating connector is a conductive slip ring. The rotary connector is not limited to the conductive slip ring, and other existing rotary connectors may be used in addition to the conductive slip ring.
Compared with the prior art, the utility model has the advantages of as follows: the utility model discloses online temperature measurement agitating unit simple structure is applicable to the online temperature measurement stirring of medicine class instruments such as medicine dissolving-out appearance. When applied to a drug dissolution instrument, the device is mainly used for solvent stirring and solvent temperature online measurement in dissolution rate experiments. In the dissolution experiment process, the bottom end of the stirring rod is always immersed in the solvent, so that the temperature of the solvent can be monitored in real time, and the authenticity and the real-time property of the temperature data of the solvent in the dissolution experiment are ensured. The utility model discloses online temperature measurement agitating unit can directly carry out real time monitoring to the menstruum temperature, improves the monitorable nature and the digital voltinism of menstruum temperature in the degree of dissolution experimentation by a wide margin, and the menstruum temperature data that obtain more has real-time and validity, more is favorable to the data judgement of degree of dissolution experiment, and the experimenter of being convenient for carries out the analysis to the experimental result of dissolving out.
Drawings
FIG. 1 is a structural sectional view of an on-line temperature measurement stirring device in the embodiment.
Detailed Description
The present invention will be described in further detail with reference to the following embodiments.
The on-line temperature measurement stirring device of the embodiment is shown in fig. 1 and comprises a stirring rod 1 and a temperature measurement element 2, wherein the temperature measurement element 2 is hermetically installed in the stirring rod 1, the temperature measurement element 2 is connected with a rotating connector 3, the rotating connector is used for being connected with a controller (not shown in the figure), the controller adopts a single chip microcomputer in the prior art, in the embodiment, the rotating connector 3 is a conductive sliding ring, and the controller reads and outputs a temperature value measured by the temperature measurement element 2.
In this embodiment, a hole 11 with an open end is formed in the stirring rod 1, the temperature measuring element 2 is installed in the hole 11, a heat-conducting filling medium cladding 4 is filled between the outer surface of the temperature measuring element 2 and the wall of the hole 11, the open end of the hole 11 is sealed by the sealing element 5, the filling medium cladding 4 is an epoxy resin cladding, and the sealing element 5 is an epoxy resin sealing element 5.
In this embodiment, the stirring rod 1 includes a connecting rod 12 and a stirring head 13, the stirring head 13 is integrally connected to the bottom end of the connecting rod 12, and the hole 11 is formed in the connecting rod 12 and reaches the bottom of the stirring head 13. In practice, the connecting rods and the mixing head are not limited to the configurations shown in FIG. 1.
The online temperature measurement stirring device is suitable for online temperature measurement stirring of a medicine inspection instrument. When being applied to the medicine and dissolving out the appearance, before the use, dissolve out the actuating lever on appearance with connecting rod 12 and medicine and link to each other to with stirring head 13 submergence in the menstruum, in carrying out degree of dissolving out the experiment process, stirring head 13 submergence all the time in the menstruum can realize the real time monitoring to the menstruum temperature, in order to ensure the authenticity and the real-time of menstruum temperature data in the degree of dissolving out experiment.

Claims (5)

1. The on-line temperature measurement stirring device is characterized by comprising a stirring rod and a temperature measurement element, wherein the temperature measurement element is hermetically arranged in the stirring rod and is connected with a rotating connector, the rotating connector is used for being connected with a controller, and the temperature value measured by the temperature measurement element is read and output through the controller.
2. The on-line temperature-measuring stirring device as claimed in claim 1, wherein a hole with an open end is formed in the stirring rod, the temperature-measuring element is installed in the hole, a heat-conducting filling medium cladding is filled between the outer surface of the temperature-measuring element and the wall of the hole, and the open end of the hole is sealed by a sealing element.
3. The on-line temperature measurement stirring device as claimed in claim 2, wherein the filling medium cladding is an epoxy resin cladding or a heat conductive silicone grease cladding, and the sealing element is an epoxy resin sealing element or a heat conductive silicone grease sealing element.
4. The on-line temperature-measuring stirring device as claimed in claim 2, wherein the stirring rod comprises a connecting rod and a stirring head, the stirring head is integrally connected to the bottom end of the connecting rod, and the hole is formed in the connecting rod and reaches the bottom of the stirring head.
5. The on-line thermometric stirring device of claim 1, wherein the rotating connector is a conductive slip ring.
CN202020583426.5U 2020-04-17 2020-04-17 Online temperature measurement agitating unit Active CN212159462U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202020583426.5U CN212159462U (en) 2020-04-17 2020-04-17 Online temperature measurement agitating unit

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202020583426.5U CN212159462U (en) 2020-04-17 2020-04-17 Online temperature measurement agitating unit

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CN212159462U true CN212159462U (en) 2020-12-15

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CN (1) CN212159462U (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113317693A (en) * 2021-04-30 2021-08-31 广东美的厨房电器制造有限公司 Stirring device and food processing equipment

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113317693A (en) * 2021-04-30 2021-08-31 广东美的厨房电器制造有限公司 Stirring device and food processing equipment

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