CN212091229U - High-efficient continuous enrichment facility of biological fermentation liquid - Google Patents

Abstract

The utility model discloses a high-efficient continuous enrichment facility of biological fermentation liquid, including security personnel filter, filtration feed pump, circulating pump, pressure vessel, RO membrane element, NF membrane element, shell and tube heat exchanger, washing jar, pipe filter, washing feed pump, temperature transmitter, flow transmitter, pressure transmitter, manometer, rotameter, supporting pipeline, valve, platen and electrical system etc.. The RO membrane elements and the NF membrane elements of the continuous concentration device are arranged in pressure containers according to 6 x 4, 6 x 4 and 6 x 4, the RO membranes are filled in the first three rows, the NF membranes are filled in the fourth row, the security filter is connected with a filtering and feeding pump, the filtering and feeding pump is connected with 4 circulating pumps, each circulating pump is respectively connected with a corresponding pressure container group, and the tubular heat exchanger is arranged on a return pipeline of each group of pressure containers.

Description

High-efficient continuous enrichment facility of biological fermentation liquid

Technical Field

The utility model relates to a concentration of biological zymotic fluid, in particular to a high-efficiency continuous concentration device of biological zymotic fluid.

Background

At present, in the production process of biological fermentation broth, most of the concentration and purification processes of the fermentation broth still adopt centrifugal separation, filtration separation, or double aqueous phase extraction, adsorption method, precipitation method and the like, the centrifugal separation usually adopts equipment such as a filter centrifuge or a decanter centrifuge and the like, and the filtration separation generally adopts methods such as plate-and-frame filtration, diatomite filtration or vacuum filtration and the like.

However, in the conventional separation process, the separation effect is not ideal due to insufficient separation precision, and in some separation methods, a new auxiliary needs to be added in the separation process or the temperature is changed for improving the separation efficiency, the addition of the new auxiliary may bring new pollution and impurities to the fermentation broth, and the change of the temperature may cause damage to the activity of the product, thereby affecting the further concentration and separation efficiency and the quality of the final product in the later period.

In view of the disadvantages of the traditional separation process, the utility model is especially provided.

Disclosure of Invention

An object of the utility model is to provide a high-efficient continuous enrichment facility of biological zymotic fluid to solve the problem that proposes among the above-mentioned background art.

In order to achieve the above object, the utility model provides a following technical scheme:

a high-efficiency continuous concentration device for biological fermentation liquor comprises a security filter, a filtering feed pump, a circulating pump, a pressure container, an RO membrane element, an NF membrane element, a tubular heat exchanger, a cleaning tank, a pipeline filter, a cleaning feed pump, a temperature transmitter, a flow transmitter, a pressure gauge, a rotor flow meter, a matched pipeline, a valve, a bedplate, an electric control system and the like. The RO membrane elements and the NF membrane elements of the continuous concentration device are arranged in a pressure container according to 6 x 4, 6 x 4 and 6 x 4, the RO membranes are filled in the first three rows, the NF membranes are filled in the fourth row, the security filter is connected with a filtering and feeding pump, the filtering and feeding pump is connected with 4 circulating pumps, each circulating pump is respectively connected with a corresponding pressure container group, and the tubular heat exchanger is arranged in a return pipeline of each group of pressure containers. The matched pipeline comprises a concentrated solution pipeline, a phase cleaning pipeline, an NF dialysate pipeline, a cleaning dialysate pipeline and a cleaning reflux pipeline, and each pipeline is connected with a corresponding interface of the equipment. The cleaning tank, the pipeline filter and the cleaning feeding pump are sequentially connected and finally connected to the inlet of the device.

The utility model discloses in, the high-efficient continuous enrichment facility of biological fermentation liquid be furnished with CIP cleaning system, can carry out quick effectual washing to the device.

The utility model discloses in, filtration feed pump, circulating pump, washing feed pump be equipped with the converter respectively.

The utility model discloses in, the security filter export be equipped with the manometer, feed pump export be equipped with pressure transmitter and temperature transmitter, the circulating pump export be equipped with flow transmitter and pressure transmitter, the pressure vessel export be equipped with the manometer, final dense liquid pipeline be equipped with the manometer, temperature transmitter and flow transmitter, clear looks pipeline be equipped with flow transmitter, the NF dialysate pipeline be equipped with flow transmitter, the washing dialysate pipeline be equipped with the flowmeter, the washing return line be equipped with the flowmeter.

The utility model discloses in, various pumps and instrument power such as temperature transmitter, flow transmitter, pressure transmitter supply power by electrical system.

The utility model discloses in, the start of filtration feed pump, circulating pump and washing feed pump stop by DCS system control, temperature transmitter, flow transmitter and pressure transmitter show that numerical value concentrates and feeds back to central control room PC end by the DCS system.

The utility model discloses in, shell and tube heat exchanger be equipped with refrigerant entry and refrigerant export, but the temperature of accurate control device operation in-process material.

In the utility model, the security filter is set to be four in two parallel and two series, and the security filter adopts a 20 μm fine filter bag.

The utility model discloses in, pressure vessel in the film element of filling be the organic membrane of formula of book.

Compared with the prior art, the beneficial effects of the utility model are that: the utility model discloses simple structure tightly promotes, and area is little, and degree of automation is high, and convenient operation is applicable to various biological zymotic fluids, need not to add the filter aid, can not introduce new impurity, and it can be at normal atmospheric temperature or even low temperature environment down operation, can avoid destroying the active ingredient in the biological zymotic fluid. The membrane element with corresponding separation precision can be replaced according to different material properties of the biological fermentation liquid, the replacement process is simple and convenient, the labor intensity of workers can be effectively reduced, the efficiency of concentrating and separating the biological fermentation liquid is improved, the membrane element has universal applicability in the field, and the membrane element has good use value and social and economic benefits.

Drawings

FIG. 1 is a product flow diagram of an efficient continuous concentration device for biological fermentation broth.

FIG. 2 is a schematic diagram of the front view of a high-efficiency continuous concentration device for biological fermentation liquid.

FIG. 3 is a schematic diagram of the right view of a high-efficiency continuous concentration device for biological fermentation liquid.

FIG. 4 is a schematic diagram of a top view of a device for continuously concentrating a biological fermentation broth.

In the figure: 1. a base; 2. a cartridge filter; 3. a filtration feed pump; 4. cleaning the tank; 5. a pipeline filter; 6. cleaning the feeding pump; 7. a circulation pump; 8. a pressure vessel; 9. a pressure gauge; 10. a pressure transmitter; 11. a temperature transmitter; 12. a flow transmitter; 13. a flow meter; 14. a shell and tube heat exchanger; 15. a concentrate line; 16. a clear phase collection pipeline; 17. an NF dialysate line; 18. cleaning the dialysate line; 19. and cleaning the return pipeline.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.

Please refer to fig. 1-4, in an embodiment of the present invention, a high-efficient continuous concentration device for biological fermentation broth, includes a base 1, a cartridge filter 2, a filtering feed pump 3, a cleaning tank 4, a pipe filter 5, a cleaning feed pump 6, a circulating pump 7, a pressure vessel 8, a pressure gauge 9, a pressure transmitter 10, a temperature transmitter 11, a flow transmitter 12, a flow meter 13, a tubular heat exchanger 14, a concentrate pipeline 15, a phase cleaning collection pipeline 16, an NF dialysate pipeline 17, a cleaning dialysate pipeline 18 and a cleaning return pipeline 19. The circulating pump 7, the pressure vessel 8, the concentrated solution pipeline 15, the clear phase collecting pipeline 16, the NF dialysate pipeline 17, the cleaning dialysate pipeline 18 and the cleaning return pipeline 19 are connected according to the process flow and are all arranged on the base 1, and the tubular heat exchanger 14 is arranged on the pipeline between the pressure vessel 8 and the concentrated solution pipe 15. The cartridge filter 2 and the filtering and feeding pump 3 are arranged on the right side of the base 1, and the cleaning tank 4, the pipeline filter 5 and the cleaning and feeding pump 6 are arranged on the right side of the base 1 in parallel with the cartridge filter 2 and the filtering and feeding pump 3. The fermentation liquor is lifted by a peripheral lifting pump, large particle impurities in the solution are removed by a security filter 2, the security filter 2 adopts a filter bag with the filtering precision of 20 microns, the filter bag is pressurized by a filtering feed pump 3 and is conveyed to the inlet end of a circulating pump 7, the fermentation liquor flows through a first stage of a pressure container 8 under the action of a first circulating pump 7, after being filtered by the first stage of the pressure container 8, concentrated liquor and a part of fermentation liquor conveyed by the filtering feed pump 3 are mixed, then the mixture flows through a second stage of the pressure container 8 under the action of a second circulating pump 7, the analogy is repeated until the fermentation liquor is filtered by a fourth stage of the pressure container 8 to form concentrated liquor, the flow of the concentrated liquor is controlled by a valve on a concentrated liquor pipeline 15, and the purpose of continuously concentrating the concentrated liquor in. The outlet end of the front third-stage pressure container 8 is connected with a return pipe and a clear phase collecting pipeline 16, the outlet end of the fourth-stage pressure container 8 is connected with a concentrated solution pipeline 15 and an NF dialysate pipeline 17, and a tubular heat exchanger 14 is arranged in the return pipe and the concentrated solution pipeline to ensure that the biological fermentation liquid is concentrated under the condition that the temperature, the pressure and other aspects meet the standard. The other end of the clear phase collecting pipeline 16 is communicated with the clear phase collecting pool or is discharged through a pipeline, the other end of the NF dialysate pipeline 17 is communicated with the NF dialysate collecting pool, and the NF dialysate is further detected and then processed in the next step. The cartridge filter 2 can adopt different types of filter bags, the filter aperture of different filter bags is generally in the range of 0.5-120 μm, the biological fermentation liquid passes through the filter bags under the action of pressure, filter residues are left in the filter bags, and filtrate flows out through the filter bags, thereby achieving the purpose of filtering. The filtering precision of the filter bag selected here is 20 μm to ensure good filtering effect on the biological fermentation liquid. In addition, each control element of the device is controlled by adopting a DCS control system. The whole device adopts a continuous concentration process, filter aids do not need to be added, new impurities cannot be introduced, the concentration process is in place in one step, the membrane element in the pressure container 8 is convenient to replace, the operation is simple, the equipment maintenance is simple, the number of easily-damaged parts is small, and the service life of the equipment is long.

As shown in fig. 1 to 4, as a further technical solution, a CIP cleaning system is further included. The CIP cleaning system is a short for in-situ cleaning system, and is widely applied to food and beverage production enterprises with higher mechanization degree such as beverages, dairy products, fruit juice, wines and the like. The in-situ cleaning means that the equipment is not disassembled or moved, namely, high-temperature and high-concentration cleaning solution is adopted to exert a strong action on the equipment, so that the contact surface between the equipment and a product is cleaned, and the production equipment with strict requirements on the sanitation level is cleaned and purified. The cleaning system is connected with the whole high-efficiency continuous biological fermentation liquid concentration device in parallel, the whole device is cleaned regularly, the equipment is guaranteed to have good cleanliness and recoverability after running for a period, the labor intensity of workers is reduced, and the production efficiency is improved.

As shown in fig. 1 to 4, as a further technical solution, a pressure gauge 9 is provided at an outlet of each section of the cartridge filter 2, so as to facilitate monitoring of the filtering condition of the filter bag in the cartridge filter 2 during the pre-filtering process, and prevent the filter bag from being broken due to the excessive impurities in the filter bag.

As shown in fig. 1 to 4, as a further technical solution, a pressure gauge 9, a pressure transmitter 10 and a temperature transmitter 11 are arranged at the front end of the feeding pipe of the device, and the pressure gauge 9 and the temperature transmitter 11 are arranged at the rear end of the feeding pipe, so that the feeding pressure can be conveniently monitored, the temperature of the device in the concentration process can be conveniently monitored, the biological fermentation liquid can be ensured to be concentrated under the conditions of proper temperature and pressure, and unnecessary production loss caused by the change of temperature and pressure can be prevented.

As shown in fig. 1 to 4, as a further technical solution, the inlet end and the outlet end of each stage of pressure vessel 8 are provided with a pressure transmitter 10 and a pressure gauge 9, so as to monitor the pressure value of the liquid in each stage of concentration process, and further make corresponding adjustment on each control element, thereby ensuring stable operation of the device.

As shown in fig. 1 to 4, as a further technical solution, each circulation pump 7 is provided with a frequency converter and a flow transmitter 12 is provided at the outlet of the corresponding circulation pump, so that the pressure and flow parameters of each stage of filtration and concentration can be conveniently adjusted by the frequency converter, the stable operation of the equipment is ensured, and the production efficiency is improved.

As shown in fig. 1 to 4, as a further technical solution, the concentrate line 15, the clear phase collecting line 16 and the NF dialysate line 17 are respectively provided with a flow transmitter 12, which facilitates control and determination of concentration multiple by the ratio of dialysate to concentrate, thereby achieving the purpose of continuous concentration.

As shown in fig. 1 to 4, as a further technical solution, the flow meters 13 are respectively disposed on the cleaning dialysate line 18 and the cleaning return line 19, so as to facilitate monitoring of the cleaning effect during the CIP cleaning process and adjustment of the cleaning scheme at any time.

As shown in fig. 1 to 4, as a further technical solution, the tube type heat exchanger 14 is provided with a refrigerant inlet and a refrigerant outlet. The tubular heat exchanger 14 performs a circulating cooling function by adopting a refrigerant with the temperature of 7 ℃, a refrigerant inlet is connected with the refrigerant, a refrigerant outlet is connected with a discharge pipeline, the circulating flow of the refrigerant in the tubular heat exchanger 14 is realized, heat is taken away by the refrigerant in the tubular heat exchanger 14, and the cooling function on the biological fermentation liquor is realized.

As a further technical solution, as shown in fig. 1 to 4, the membrane element filled in the pressure vessel 8 is a roll-type organic membrane. The organic membrane is mainly made of high molecular materials, and can be divided into a flat membrane, a tubular membrane, a capillary membrane, a hollow fiber membrane and other forms according to different membrane shapes.

As shown in figures 1 to 4, as a further technical scheme, the pumps, the temperature transmitter, the flow transmitter, the pressure transmitter and other instrument power supplies in the high-efficiency continuous concentration device of the biological fermentation liquid are all powered by an electric control system. And the start and stop of the pumps are controlled by the DCS, and the display values of the temperature transmitter, the flow transmitter and the pressure transmitter are centrally fed back to the PC end of the central control room by the DCS. The device is convenient for remotely monitoring the start and stop of equipment and various data indexes of the continuous concentration device, reduces the labor intensity of workers and improves the production efficiency.

The utility model discloses a theory of operation is:

the utility model discloses simple structure tightly promotes, and area is little, and degree of automation is high, and convenient operation is applicable to various biological zymotic fluids, need not to add the filter aid, can not introduce new impurity, and it can be at normal atmospheric temperature or even low temperature environment down operation, can avoid destroying the active ingredient in the biological zymotic fluid. The membrane element with corresponding separation precision can be replaced according to different material properties of the biological fermentation liquid, the replacement process is simple and convenient, the labor intensity of workers can be effectively reduced, the efficiency of concentrating and separating the biological fermentation liquid is improved, the membrane element has universal applicability in the field, and the membrane element has good use value and social and economic benefits.

The above, only be the concrete implementation of the preferred embodiment of the present invention, but the protection scope of the present invention is not limited thereto, and any person skilled in the art is in the technical scope of the present invention, according to the technical solution of the present invention and the utility model, the concept of which is equivalent to replace or change, should be covered within the protection scope of the present invention.

Claims (7)

1. The utility model provides a high-efficient continuous enrichment facility of biological fermentation liquid, includes cartridge filter, filters feed pump, circulating pump, pressure vessel, RO membrane element, NF membrane element, shell and tube heat exchanger, washs jar, pipe filter, washs feed pump, temperature transmitter, flow transmitter, pressure transmitter, manometer, rotor flow meter, supporting pipeline, valve, platen and electrical system, its characterized in that: RO membrane elements and NF membrane elements of a continuous concentration device are arranged in a pressure container according to 6 x 4, the first three rows are filled with RO membranes, the fourth row is filled with NF membranes, a security filter is connected with a filtering feed pump, the filtering feed pump is connected with 4 circulating pumps, each circulating pump is respectively connected with a corresponding pressure container group, a tubular heat exchanger is arranged on a return pipeline of each group of pressure containers, a matched pipeline comprises a concentrated solution pipeline, a clear phase pipeline, an NF dialysate pipeline, a cleaning dialysate pipeline and a cleaning return pipeline, each pipeline is respectively connected with a corresponding interface of equipment, a cleaning tank, a pipeline filter and a cleaning feed pump are sequentially connected and finally connected to an inlet of the device, instrument power supplies of pumps in the device, a temperature transmitter, a flow transmitter and a pressure transmitter are all powered by an electric control system, and the start and stop of the pumps are controlled by the electric control system, the display values of the temperature transmitter, the flow transmitter and the pressure transmitter are centrally fed back to the PC end of the central control room by the DCS system.

2. The apparatus of claim 1, wherein the apparatus is equipped with a CIP cleaning system to clean the apparatus rapidly and efficiently.

3. A high efficiency continuous concentrating apparatus for biological fermentation broth according to claim 1, wherein the filtration feed pump, the circulation pump and the washing feed pump are respectively provided with a frequency converter.

4. The apparatus of claim 1, wherein the cartridge filter outlet is provided with a pressure gauge, the feed pump outlet is provided with a pressure transmitter and a temperature transmitter, the circulating pump outlet is provided with a flow transmitter and a pressure transmitter, and the pressure vessel outlet is provided with a pressure gauge.

5. The apparatus of claim 1, wherein the tubular heat exchanger has a coolant inlet and a coolant outlet, so as to precisely control the temperature of the material during the operation of the apparatus.

6. The apparatus of claim 1, wherein the cartridge filter is configured as four filters, and the cartridge filter is a 20 μm fine filter bag.

7. The apparatus for high efficiency continuous concentration of biological fermentation broth according to claim 1, wherein the membrane element filled in the pressure vessel is a roll-type organic membrane.

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