CN211935180U - Nerve stimulation array system - Google Patents
Nerve stimulation array system Download PDFInfo
- Publication number
- CN211935180U CN211935180U CN201922271965.5U CN201922271965U CN211935180U CN 211935180 U CN211935180 U CN 211935180U CN 201922271965 U CN201922271965 U CN 201922271965U CN 211935180 U CN211935180 U CN 211935180U
- Authority
- CN
- China
- Prior art keywords
- array system
- flexible substrate
- neurostimulation
- holes
- layer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Images
Landscapes
- Photovoltaic Devices (AREA)
Abstract
The utility model discloses a nerve stimulation array system, which comprises a flexible substrate, a photoelectric response layer and an electrode layer; the photoelectric response layer is embedded in the flexible substrate, the photoelectric response layer is formed by arranging photoelectric conversion material arrays, and the electrode layer is located on the photoelectric response layer. The nerve stimulation array system has the advantages of simple structure, low cost, good flexibility and good biocompatibility, can realize photoresponse electrical stimulation of spatial resolution, and can be used in the field of different in-vivo nerve electrical stimulation of eyes, brains and the like.
Description
Technical Field
The utility model relates to a biomedical engineering technical field especially relates to a neural amazing array system.
Background
The electrode-based nerve stimulation system is widely used for treating various diseases related to peripheral nerve and central nerve injury and the like, and has great potential in the aspect of treating diseases such as limb paralysis, depression, deafness, blindness and the like. In particular, in recent years, the artificial retina prosthesis system based on the high-density electrode array developed by the company of Second Sight Medical Products in the united states can effectively restore part of the visual ability of patients with advanced retinal degenerative diseases, and provides a feasible solution for such blindness-causing diseases which cannot be clinically treated in the past. However, such artificial retina prosthesis systems need to integrate a plurality of functional modules such as a visual signal acquisition module, a wireless signal transmission and reception module, an integrated chip control module, an electrode stimulation module, etc., and have high manufacturing cost, high integration difficulty and difficult implantation, thereby greatly limiting the popularization and application of such devices.
SUMMERY OF THE UTILITY MODEL
In view of this, the utility model provides a novel neural amazing array system, it has photoelectric conversion material and the metal electrode layer that the array was arranged, simple structure, and the cost of manufacture is low, need not integrated complicated signal acquisition module, wireless signal transmission receiving module and integrated chip control module and just can realize having the neural electric stimulation of photoresponse of spatial resolution, can be used to different neural amazing fields such as visual stimulation, cerebral cortex stimulation.
Specifically, the utility model provides a neurostimulation array system, include: the photoelectric response layer is embedded into the flexible substrate, the photoelectric response layer is formed by arranging photoelectric conversion material arrays, and the electrode layer is located on the photoelectric response layer.
In the present invention, the electrode of the electrode layer is located on the surface of the photoelectric conversion material of the photoelectric response layer. Obviously, the electrode layer is also arranged by the conductive material array.
Optionally, the thickness of the electrode layer is 50-300 nm.
Optionally, the flexible substrate has a thickness of 5-500 μm.
Wherein the thickness of the photoelectric response layer is less than or equal to the thickness of the flexible substrate. Preferably, the thickness of the photoresponsive layer is equal to the thickness of the flexible substrate, for example between 5 and 500 μm.
In an embodiment of the present invention, the flexible substrate has an array of holes, and the photoelectric response layer is filled in the holes of the array of holes; the holes are blind holes or through holes. The depth direction of the hole is parallel to the thickness direction of the flexible substrate. When the hole of the flexible substrate is a through hole penetrating through the thickness direction of the flexible substrate, the thickness of the photoelectric response layer is equal to that of the flexible substrate.
Further, the holes are circular, triangular, quadrilateral, polygonal or other irregular shapes. Accordingly, the cross section of the photoelectric conversion material of the photoelectric response layer is circular, triangular, quadrilateral, polygonal or other irregular shapes.
Preferably, the holes are circular, the diameter of the holes being between 100 μm and 2 mm.
The utility model discloses in, the material of flexible basement is insulating material to can effectively restrain photoelectronic diffusion, make nerve stimulation array system realizes having the electro photoluminescence of resolution ratio. The material of the flexible substrate may be a flexible insulating polymer, the choice of which depends on the end use and the desired effect of the use. For example, to ensure that a film substrate capable of effectively adhering to a curved surface structure can be formed, it is necessary to ensure that the flexible substrate material has good film formability and good mechanical properties under high curvature.
Optionally, the material of the flexible substrate includes one or more of polyimide, polydimethylsiloxane, polyethylene terephthalate, parylene and photoresist. The photoresist may be a positive or negative photoresist, and may specifically be, but not limited to, SU8 photoresist, AZ photoresist, and the like.
The material of the electrode layer is selected from at least one of platinum, gold, titanium, iridium, palladium, niobium, tantalum and alloys thereof, titanium nitride (TixNy), iridium oxide (IrOx), Indium Tin Oxide (ITO), aluminum-doped zinc oxide (AZO), fluorine-doped tin dioxide (FTO), and phosphorus-doped tin dioxide (PTO), but is not limited thereto.
The utility model discloses in, the photoelectric response layer should possess better photoelectric conversion efficiency and biocompatibility. Preferably, the photoelectric conversion material constituting the photoelectric response layer may be selected from at least one of the following substances having different photoelectric response mechanisms: the photovoltaic material, the photoinduced deformation material composite piezoelectric material and the up-conversion material composite photovoltaic material.
Wherein the photovoltaic material can absorb photon energy in a visible light region (400-800nm) and directly generate photoelectrons. The composite piezoelectric material of the photoinduced deformation material firstly depends on the photoinduced deformation material to generate deformation under the excitation of light rays in a visible light wave band (400-800nm), and then the deformation is transmitted to the piezoelectric material to generate a piezoelectric signal. The up-conversion material composite photovoltaic material absorbs photon energy in a near infrared region (780-2526nm) and emits photons with wavelengths in a visible light region (400-800nm), and then the photovoltaic material with response wavelength bands in the visible light region is excited to generate photoelectrons. When the photoelectric conversion material is an up-conversion material composite photovoltaic material, the obtained photoelectric response layer of the nerve stimulation system can respond to light in a near infrared region (808 and 2500nm) beyond a visible light region, so that the super-visual light perception capability is obtained.
Wherein the photovoltaic material is at least one of the following substances: monocrystalline silicon solar cell materials, thin-film solar cell materials represented by amorphous silicon, copper indium gallium selenide thin films and cadmium telluride thin films, dye-sensitized solar cell materials based on titanium dioxide and compounds thereof, perovskite solar cell materials based on perovskite type organic metal halides, and organic photovoltaic materials of polyacetylene, polythiophene, polyaniline, polypyrrole and derivatives and copolymers thereof. Examples of the perovskite-type organic metal halide include methylammonium lead iodide, methylammonium lead bromide, methylammonium lead chloride, and the like.
The photoinduced deformation material composite piezoelectric material is any one combination of the photoinduced deformation material and the piezoelectric material, wherein the photoinduced deformation material is at least one of the following materials: a photoisomerization material represented by azobenzene and a derivative thereof, spiropyran and a derivative thereof; a ferroelectric inorganic photoinduced deformation material represented by lead titanate, barium titanate, potassium niobate, lithium tantalate, bismuth layer-like perovskite structure ferroelectric, tungsten bronze type ferroelectric, bismuth ferrite, potassium dihydrogen phosphate, ammonium trinitrate sulfate, rosette, perovskite type organic metal halide ferroelectric; non-ferroelectric inorganic photo-deformation materials represented by strontium ruthenate, silicon, cadmium sulfide, gallium arsenide; wherein the piezoelectric material is at least one of the following materials: piezoelectric crystals represented by quartz crystals, lithium gallate, lithium germanate, titanium germanate, and lithium tantalate; piezoelectric ceramics represented by barium titanate, lead zirconate titanate, lead metaniobate, and lead barium lithium niobate; piezoelectric polymers represented by polyvinylidene fluoride ferroelectric polymers, odd-numbered nylons, polyacrylonitriles, vinylidene cyanide and copolymers thereof, polyureas, polyphenylcyanoethers, polyvinyl chloride, polyvinyl acetate, polypropylene, polytetrafluoroethylene. Among them, as the polyvinylidene fluoride-based ferroelectric polymer, poly (vinylidene fluoride-trifluoroethylene) [ P (VDF-TrFE) copolymer ], poly (vinylidene fluoride-chlorofluoroethylene) [ P (VDF-CFE) copolymer ], poly (vinylidene fluoride-chlorotrifluoroethylene) [ P (VDF-CTFE) copolymer ], poly (vinylidene fluoride-hexafluoropropylene) [ P (VDF-HFP) copolymer ], poly (vinylidene fluoride-trifluoroethylene-chlorofluoroethylene) [ P (VDF-TrFE-CFE) terpolymer ], poly (vinylidene fluoride-trifluoroethylene-chlorotrifluoroethylene) [ P (VDF-TrFE-CTFE) terpolymer ], and poly (vinylidene fluoride-trifluoroethylene-hexafluoropropylene) [ P (VDF-TrFE-CTFE) terpolymer ] may be cited.
Wherein the up-conversion material composite photoelectric material is a composite material formed by up-conversion nanometer and at least one of the following materials: polyacetylene, polythiophene, polyaniline, polypyrrole and derivatives and copolymers thereof. Wherein the up-conversion nanoparticles comprise a host material, a sensitizer and an activator, wherein the host material is NaYF4Or NaGdF4The sensitizer is Yb, and the activator is Er, Tm or Ho. Specifically, the up-conversion fluorescent material comprises NaYF4:Yb3+,Er3+、YF3:Yb3+,Er3+、NaYF4:Yb3+,Tm3+、YF3:Yb3+,Tm3+、NaYF4:Yb3+,Ho3+And YF3:Yb3+,Ho3+At least one of (1).
The utility model provides a neural amazing array system, including the flexible basement, the photoelectric response layer that the photoelectric conversion material that the setting was arranged by the array on the flexible basement constitutes to and set up the array electrode layer on the photoelectric response layer, need not to integrate complicated signal acquisition module again, wireless signal transmission receiving module, multifunctional module such as integrated chip control module, photoelectric response layer wherein can directly produce the photoelectron that has spatial resolution under the light stimulation and be used for amazing nerve, the neural electro-stimulation that has spatial resolution is realized to the electrode layer of accessible array again. The nerve stimulation array system has the advantages of simple structure, low cost, good flexibility, high photoelectric conversion efficiency and good biocompatibility, can realize photoresponse electric stimulation of spatial resolution, and can be used in different nerve electric stimulation fields of eyes, brains and the like.
Drawings
Fig. 1 is a schematic cross-sectional view of a neurostimulation array system according to embodiment 1 of the present invention;
FIG. 2 is a top view (a) and a bottom view (b) of the neurostimulation array system of FIG. 1;
fig. 3 is a schematic structural diagram of a neurostimulation array system according to embodiment 3 of the present invention;
fig. 4 is a schematic structural diagram of a neurostimulation array system according to embodiment 4 of the present invention;
fig. 5 is a schematic structural diagram of a neurostimulation array system in embodiment 5 of the present invention.
Detailed Description
The present invention will be further described with reference to specific embodiments.
Example 1
A nerve stimulation array system is structurally shown in fig. 1, and comprises a flexible substrate 10, a photoelectric response layer 20 embedded in the flexible substrate 10, and an electrode layer 30 covering the surface of the photoelectric response layer 20, wherein the photoelectric response layer 20 is formed by arranging photoelectric conversion material arrays.
In the present embodiment, as shown in fig. 2, the flexible substrate 10 has a hole array formed by 9 circular through holes with a diameter of 2mm, and the photoelectric response layer 20 is filled in the holes of the hole array; the thickness of the photoelectric response layer 20 is 200 μm, and the material thereof is copper indium gallium selenide thin-film solar cell material. The thickness of the flexible substrate 10 is 200 μm, and the material thereof is Polydimethylsiloxane (PDMS); the electrode layer 30 is 300nm thick and made of Indium Tin Oxide (ITO).
The utility model discloses embodiment 1's nerve stimulation array system has 9 electrodes, and wherein single electrode is the sunlight simulation lighting system (100 mW/cm) of visible light region (400-2) The output voltage generated under the excitation of the optical nerve stimulation device is more than 5V, the output current is more than 10mA, and the optical nerve stimulation device can stimulate visual ganglion cells to show excitability.
Example 2
A nerve stimulation array system is structurally shown in figures 1-2 and comprises a flexible substrate 10, a photoelectric response layer 20 embedded in the flexible substrate 10 and an electrode layer 30 covering the surface of the photoelectric response layer 20, wherein the photoelectric response layer 20 is formed by arranging photoelectric conversion material arrays.
In the present embodiment, the flexible substrate 10 has a hole array formed by 9 circular through holes having a diameter of 200 μm, and the photo-responsive layer 20 is filled in the holes of the hole array; the thickness of the photoelectric response layer 20 is 5 μm, and the material thereof is a titanium dioxide nano array with photovoltaic characteristics. The thickness of the flexible substrate 10 is 5 μm, and the material thereof is polyimide; the electrode layer 30 is 50nm thick and made of Au.
The utility model discloses embodiment 2's nerve stimulation array system has 9 electrodes, and wherein single electrode is the sunlight simulation lighting system (100 mW/cm) of visible light region (400-2) The output voltage generated by the stimulation is more than 500mV, the output current is more than 100 muA, and the stimulation can stimulate the visual ganglion cells to show excitability.
Example 3
A nerve stimulation array system is shown in fig. 3, and comprises a flexible substrate 10, a photoelectric response layer 20 embedded in the flexible substrate 10, and an electrode layer 30 covering the surface of the photoelectric response layer 20, wherein the photoelectric response layer 20 is formed by arranging photoelectric conversion material arrays.
In the present embodiment, the flexible substrate 10 has a hole array formed by 9 square through holes with a side of 500 μm, and the photoelectric response layer 20 is filled in the through holes of the hole array, but the through holes are not filled; the thickness of the photoelectric response layer 20 is 9.8 μm, and the material is a perovskite type light absorption substance with photoelectric response characteristic, such as methotrexate-lead-iodine. The thickness of the flexible substrate 10 is 10 μm, and the material thereof is parylene; the electrode layer 30 is 300nm thick and made of Au.
The utility model discloses embodiment 3's single electrode of nerve stimulation array system is the sunlight simulation lighting system (100 mW/cm) of visible light region (400 supple with power 800nm) at the transmission wave band2) The output voltage generated by the stimulation is more than 5V, the output current is more than 500 muA, and the visual ganglion cells can be stimulated to show excitability.
Example 4
A nerve stimulation array system capable of being simply integrated is shown in fig. 4 and comprises a flexible substrate 10, a photoelectric response layer 20 embedded in the flexible substrate 10 and an electrode layer 30 covering the surface of the photoelectric response layer 20, wherein the photoelectric response layer 20 is formed by arranging photoelectric conversion material arrays.
In the present embodiment, the flexible substrate 10 has a hole array formed by 9 circular through holes having a diameter of 500 μm, and the photo-responsive layer 20 is filled in the through holes of the hole array, but the through holes are not filled; the thickness of the photoelectric response layer 20 is 190 μm, and the material thereof is organic photovoltaic material poly (3-n-hexylthiophene). The thickness of the flexible substrate 10 is 200 μm, and the material thereof is polydimethylsiloxane; the electrode layer 30 is 50nm thick and made of Pt.
The nerve stimulation array system of the embodiment 4 has 9 electrodes, wherein a single electrode is a sunlight simulation illumination system (100 mW/cm) with an emission waveband of visible light region (400-800nm)2) The output voltage generated by the stimulation is more than 200mV, the output current is more than 100 muA, and the stimulation can stimulate the visual ganglion cells to show excitability.
Example 5
As shown in fig. 5, the neurostimulation array system comprises a flexible substrate 10, a photoelectric response layer 20 embedded in the flexible substrate 10, and an electrode layer 30 covering the surface of the photoelectric response layer 20, wherein the photoelectric response layer 20 is formed by arranging photoelectric conversion material arrays.
In the present embodiment, the flexible substrate 10 has a hole array formed by 9 circular blind holes with a diameter of 200 μm, and the photoelectric response layer 20 is filled in the blind holes of the hole array; the thickness of the photoelectric response layer 20 is 18 μm, and the material is poly (vinylidene fluoride-trifluoroethylene) which is prepared by compounding azobenzene derivative with the photo-induced deformation characteristic and has the piezoelectric effect. The thickness of the flexible substrate 10 is 20 μm, and the material thereof is polyethylene terephthalate (PET); the electrode layer 30 is 50nm thick and made of Pt.
The neurostimulation array system of this example 5 had 9 electrodes, with the individual electrodes being visible light (100 mW/cm) at wavelengths of 405, 532 and 650nm, respectively2) The output voltage generated by the stimulation is more than 20mV, the output current is more than 100 muA, and the stimulation can stimulate the visual ganglion cells to show excitability.
Example 6
A nerve stimulation array system is shown in fig. 1 and comprises a flexible substrate 10, a photoelectric response layer 20 embedded in the flexible substrate 10 and an electrode layer 30 covering the surface of the photoelectric response layer 20, wherein the photoelectric response layer 20 is formed by arranging photoelectric conversion material arrays.
In the present embodiment, the flexible substrate 10 has a hole array formed by 9 circular through holes having a diameter of 200 μm, and the photo-responsive layer 20 is filled in the holes of the hole array; the thickness of the photoelectric response layer 20 is 20 μm, and the material is strontium ruthenate with photoinduced deformation characteristic and poly (vinylidene fluoride-trifluoroethylene) with piezoelectric effect. The thickness of the flexible substrate 10 is 20 μm, and the material thereof is polyethylene terephthalate (PET); the electrode layer 30 is 50nm thick and made of Pt.
The neurostimulation array system of this example 6 was used for visible light (100 mW/cm) with wavelengths of 532 nm and 650nm, respectively2) Is excited to produce an outputThe voltage is more than 50mV, the output current is more than 200 muA, and the visual ganglion cells can be stimulated to show excitability.
Example 7
A nerve stimulation array system is shown in fig. 1 and comprises a flexible substrate 10, a photoelectric response layer 20 embedded in the flexible substrate 10 and an electrode layer 30 covering the surface of the photoelectric response layer 20, wherein the photoelectric response layer 20 is formed by arranging photoelectric conversion material arrays.
In the present embodiment, the flexible substrate 10 has a hole array formed by 9 circular through holes having a diameter of 200 μm, and the photo-responsive layer 20 is filled in the holes of the hole array; the thickness of the photoelectric response layer 20 is 20 μm, and the material is the up-conversion nano-particle NaYF4:Yb3+,Er3+The composite organic photovoltaic material is poly (3-n-hexylthiophene). The thickness of the flexible substrate 10 is 20 μm, and the material thereof is polyethylene terephthalate (PET); the electrode layer 30 is 50nm thick and made of Pt.
The emission wavelengths of the single electrodes of the neurostimulation array system of the embodiment 7 are respectively 808nm, 1200nm and 2500nm near-infrared lamps (100 mW/cm)2) The output voltage generated by the stimulation is more than 200mV, the output current is more than 100 muA, and the stimulation can stimulate the visual ganglion cells to show excitability.
The above-described embodiments only represent exemplary embodiments of the present invention, and the description thereof is more specific and detailed, but not construed as limiting the scope of the invention. It should be noted that, for those skilled in the art, without departing from the spirit of the present invention, several variations and modifications can be made, which are within the scope of the present invention. Therefore, the protection scope of the present invention should be subject to the appended claims.
Claims (10)
1. A neurostimulation array system, which is characterized by comprising a flexible substrate, a photoelectric response layer and an electrode layer; the photoelectric response layer is embedded in the flexible substrate, the photoelectric response layer is formed by arranging photoelectric conversion material arrays, and the electrode layer is located on the photoelectric response layer.
2. The neurostimulation array system of claim 1, wherein the thickness of the electro-optic responsive layer is less than or equal to the thickness of the flexible substrate.
3. The neurostimulation array system according to claim 2, wherein the thickness of the electro-optical response layer is 5-500 μm, and the thickness of the flexible substrate is 5-500 μm.
4. The neurostimulation array system according to claim 1, wherein the flexible substrate is provided with an array of holes, and the photoelectric response layer is filled in the holes of the array of holes; the holes are through holes or blind holes.
5. The neurostimulation array system of claim 4, wherein the holes are circular, triangular, quadrilateral or other polygonal shapes.
6. The neurostimulation array system of claim 4, wherein the holes are circular with a diameter of 100 μm-2 mm.
7. The neurostimulation array system according to claim 1, wherein the thickness of the electrode layer is 50-300 nm.
8. The neurostimulation array system of claim 1, wherein the flexible substrate is made of polyimide, polydimethylsiloxane, polyethylene terephthalate, parylene, or photoresist.
9. The neurostimulation array system according to claim 1, wherein the photoelectric conversion material is a photovoltaic material, a photoinduced deformation material composite piezoelectric material or an up-conversion material composite photoelectric material.
10. The neurostimulation array system of claim 1, wherein the electrode layer is made of a material selected from platinum or an alloy thereof, gold or an alloy thereof, titanium or an alloy thereof, iridium or an alloy thereof, palladium or an alloy thereof, niobium or an alloy thereof, tantalum or an alloy thereof, titanium nitride, iridium oxide, indium tin oxide, aluminum-doped zinc oxide, fluorine-doped tin dioxide or phosphorus-doped tin dioxide.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201922271965.5U CN211935180U (en) | 2019-12-13 | 2019-12-13 | Nerve stimulation array system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201922271965.5U CN211935180U (en) | 2019-12-13 | 2019-12-13 | Nerve stimulation array system |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN211935180U true CN211935180U (en) | 2020-11-17 |
Family
ID=73175851
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201922271965.5U Active CN211935180U (en) | 2019-12-13 | 2019-12-13 | Nerve stimulation array system |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN211935180U (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112972888A (en) * | 2019-12-13 | 2021-06-18 | 中国科学院深圳先进技术研究院 | Nerve stimulation array system and preparation method thereof |
| CN113285026A (en) * | 2021-04-29 | 2021-08-20 | 北京航空航天大学 | Full-flexible ultraviolet detector based on high polymer material and preparation and application thereof |
| CN114191682A (en) * | 2021-12-22 | 2022-03-18 | 驻马店市精神病医院(驻马店市第二人民医院) | Molecular spontaneous polarization-based perturbation type depression patient auxiliary reading device |
-
2019
- 2019-12-13 CN CN201922271965.5U patent/CN211935180U/en active Active
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112972888A (en) * | 2019-12-13 | 2021-06-18 | 中国科学院深圳先进技术研究院 | Nerve stimulation array system and preparation method thereof |
| CN113285026A (en) * | 2021-04-29 | 2021-08-20 | 北京航空航天大学 | Full-flexible ultraviolet detector based on high polymer material and preparation and application thereof |
| CN114191682A (en) * | 2021-12-22 | 2022-03-18 | 驻马店市精神病医院(驻马店市第二人民医院) | Molecular spontaneous polarization-based perturbation type depression patient auxiliary reading device |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN211935180U (en) | Nerve stimulation array system | |
| US7494840B2 (en) | Optical device with IrOx nanostructure electrode neural interface | |
| KR101759824B1 (en) | Self-sustaining smart window system | |
| EP2098264B1 (en) | Active retina implant with a number of image elements | |
| US20220226640A1 (en) | Photosensitive pixel structure with increased light absorption and photosensitive implant | |
| US20050268957A1 (en) | Power source device | |
| JP2018514338A (en) | Photosensitive pixel with shunt resistor | |
| CN111013014A (en) | Nerve tissue stimulation composite material, composite membrane and nerve tissue prosthesis | |
| Karatum et al. | Electrical stimulation of neurons with quantum dots via near-infrared light | |
| US11171163B2 (en) | Photosensitive pixel structure with wrapped resistor | |
| ES2757533T3 (en) | Photosensitive pixel structure with front side coating | |
| Wang et al. | Implantable photoelectronic charging (I-PEC) for medical implants | |
| CN112972888A (en) | Nerve stimulation array system and preparation method thereof | |
| JP2008029838A (en) | OPTICAL DEVICE HAVING NEURAL INTERFACE OF IrOX NANOSTRUCTURE ELECTRODE | |
| US10729912B2 (en) | Insertable photoelectric device using absorption of light penetrating skin and electronic apparatus having same photoelectric device | |
| Ohta | Artificial retina IC | |
| KR102531735B1 (en) | Micro photovoltaic stimulator and manufacturing method thereof | |
| KR102514572B1 (en) | Implantable ocular micro photovoltaic stimulator and manufacturing method thereof | |
| CN117835808A (en) | Preparation method and application of silk fibroin-based memristor with ultralow working current and working voltage | |
| DE102011118902B4 (en) | Printable photovoltaic electrochromic device | |
| US9108042B2 (en) | Device for stimulating neural regeneration and fabrication method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant |