CN211800646U - Even formula granulation machine that sways of pelletization - Google Patents

Even formula granulation machine that sways of pelletization Download PDF

Info

Publication number
CN211800646U
CN211800646U CN202020289239.6U CN202020289239U CN211800646U CN 211800646 U CN211800646 U CN 211800646U CN 202020289239 U CN202020289239 U CN 202020289239U CN 211800646 U CN211800646 U CN 211800646U
Authority
CN
China
Prior art keywords
transverse vibration
stirring
screen cloth
support frame
vibration screen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN202020289239.6U
Other languages
Chinese (zh)
Inventor
蒋志君
秦飞
周俊枭
解仁淦
范罗权
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
JIANGSU CHANGTAI PHARMACEUTICAL CO Ltd
Original Assignee
PHARMAMAX CORP
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PHARMAMAX CORP filed Critical PHARMAMAX CORP
Priority to CN202020289239.6U priority Critical patent/CN211800646U/en
Application granted granted Critical
Publication of CN211800646U publication Critical patent/CN211800646U/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Landscapes

  • Combined Means For Separation Of Solids (AREA)

Abstract

The utility model provides an even formula granulation machine that sways of pelletization, the on-line screen storage device comprises a base, a machine support, drive assembly, the feeder hopper, the feed opening, the support frame, the filter screen, the stirring subassembly, transverse vibration drive assembly, transverse vibration screen cloth and transverse vibration screen cloth support frame, the stirring subassembly is located the filter screen and surrounds the region in, transverse vibration drive assembly and transverse vibration screen cloth are connected, transverse vibration screen cloth and transverse vibration screen cloth support frame sliding connection, transverse vibration screen cloth is located the feed opening under, and transverse vibration screen cloth's bottom is the screen cloth. The utility model discloses a formula granulation machine sways sets up transverse vibration's screen cloth under the discharge gate of granulation machine, can carry out the secondary to the granule through the filter screen and divide the sieve to obtain the more even granule of granule, when the granulation machine of this structure guarantees the production effect, increase production efficiency, can realize the screening of material when the ejection of compact, need not post processing, further improve production efficiency, overall structure reasonable in design, convenient to use, the maintenance of being convenient for.

Description

Even formula granulation machine that sways of pelletization
Technical Field
The utility model belongs to the technical field of pharmaceutical equipment, specifically, relate to an even formula granulation machine that sways of pelletization.
Background
The oscillating granulator is used for grinding wet powder into required particles and also can be used for grinding blocky dry powder into required particles. The main characteristics are that the screen is easy to assemble and disassemble, the tightness can be adjusted, the disassembly is convenient, and the cleaning is easy. The swing type granulator is widely applied to the pharmaceutical industry. The machine rotates mechanically, the roller transmits automatically under the action of friction force, and the powdery material is discharged from the screen holes under the action of the positive and negative rotation of the rotary cylinder and is sent out of the machine; the particle size and density of the particles can be controlled to a certain degree by adjusting the tightness of the screen and the rotating speed of the roller. The machine is granulated at normal temperature, powder is added into a hopper during working, and is directly granulated and formed at one time, so that the cost is saved, and the material quality is improved. The prepared granules are bright and clean, have moderate hardness, and are convenient for tablet preparation, packaging and storage, capsule preparation and the like.
However, the existing swing type granulation machine has the defects that the unqualified granules cannot be separated after production, the granulation efficiency and quality are affected, the workload of later-stage granule dispersion is increased, the labor intensity of workers is improved, and the uniformity and appearance of the granules are affected.
SUMMERY OF THE UTILITY MODEL
Utility model purpose: the utility model aims at providing a swing granulator with uniform granulation, which solves the problems that the swing granulator can not divide the granules with different sizes generated in the granulation process, the granules are not uniform, manual screening is needed in the later period, and a large amount of manpower is consumed; and the surface of the material is easy to breed bacteria in the process of granulating, which can affect the quality of granulating.
The technical scheme is as follows: the utility model provides a swing type granulator with uniform granulation, which comprises a base, a frame, a driving component, a feeding hopper, a feed opening, a supporting frame, a filter screen, a stirring component, a transverse vibration driving component, a transverse vibration screen and a transverse vibration screen supporting frame, wherein the frame, the driving component, the transverse vibration driving component and the transverse vibration screen supporting frame are all fixedly arranged on the base, the driving component is positioned in the space covered by the frame and is connected with the stirring component, the supporting frame is fixedly arranged on the outer wall of the frame, the filter screen is arranged in the supporting frame, the feeding hopper and the feed opening are respectively arranged at the upper end part and the lower end part of the supporting frame, the stirring component is positioned in the area surrounded by the filter screen, the transverse vibration driving component is connected with the transverse vibration screen, the transverse vibration screen is connected with the transverse vibration screen supporting frame in a sliding way, the transverse vibrating screen is located right below the feed opening, and the bottom of the transverse vibrating screen is a screen. The utility model discloses an even formula granulation machine that sways of pelletization through reasonable structural design for the material through the granulation machine screening can carry out the secondary screening, thereby obtains the more even material of granularity.
Further, above-mentioned even formula granulation machine that sways of pelletization, base and frame are "L" type setting.
Further, the even formula granulation machine that sways of foretell pelletization, drive assembly includes stirring driving motor, action wheel, gear belt, follows driving wheel and stirring driving motor fixing base, the fixed setting on the base of stirring driving motor fixing base, stirring driving motor is fixed to be set up on stirring driving motor fixing base to stirring driving motor and action wheel are connected, the action wheel passes through the gear belt and is connected from the driving wheel, connect from driving wheel and stirring subassembly. The drive assembly of this structure can drive the stirring subassembly and constantly rotate to carry out breaing up of material.
Further, foretell even formula granulation machine that sways of pelletization, the stirring subassembly includes stirring pivot, a set of stirring connecting rod and a set of stirring rod, the stirring pivot is connected with from the driving wheel, the stirring connecting rod sets up between stirring pivot and stirring rod, a set of stirring rod uses the stirring pivot to set up according to annular array's mode as the center, the cross-section of stirring rod is triangle-shaped. The stirring rod with the triangular cross section is convenient for scattering materials, so that particles with composite size requirements can be smoothly screened out.
Further, foretell even formula granulation machine that sways, the symmetry is equipped with two filter screens on the support frame and tightens up the valve, the both ends of filter screen tighten up the valve with two filter screens respectively and are connected. Two filter screens that set up tighten up the valve, can follow the elasticity of both sides regulation filter screen to adjust the distance between filter screen and the stirring subassembly.
Further, foretell even formula granulation machine that sways, transverse vibration drive assembly includes vertical support plate, transverse vibration driving motor, eccentric wheel and connecting plate, vertical support plate passes through the bolt fastening and sets up on the base, transverse vibration driving motor is fixed to be set up in vertical support plate to transverse vibration driving motor is connected with the eccentric wheel, the one end and the eccentric wheel of connecting plate are articulated to the other end and the transverse vibration screen cloth of connecting plate are articulated. The transverse vibration driving assembly of the structure is reasonable in structure setting, and reciprocating vibration of the transverse vibration screen can be conveniently and rapidly realized.
Further, foretell even formula granulation machine that sways, be equipped with articulated connecting seat on the lateral wall of transverse vibration screen cloth near vertical support plate one end, articulated connecting seat is articulated with the one end of connecting plate. The hinged connecting seat is convenient for connecting the connecting plates.
Further, foretell even formula granulation machine that sways, the cross-section of transverse vibration screen support frame is the U type, the upper end of transverse vibration screen support frame is the opening form to go up the symmetry in two relative inner walls of transverse vibration screen support frame and be equipped with two slide rails, the symmetry is equipped with the slider on the inner wall that transverse vibration screen is close to transverse vibration screen support frame both sides, slider and slide rail sliding connection. The transverse vibration screen support frame of this structure can enough carry out the support of transverse vibration screen cloth, and the slide rail and the slider structure that set up simultaneously can guarantee the smooth reciprocating motion on transverse vibration screen cloth support frame of transverse vibration screen cloth.
Further, foretell even formula granulation machine that sways, be equipped with the storage case on the bottom plate of transverse vibration screen cloth support frame, the storage case is located transverse vibration screen cloth under. The storage case that sets up can receive the granule that the transverse vibration screen cloth sieved, need not the manual work and collects labour saving and time saving.
Further, foretell even formula granulation machine that sways of pelletization, the flaring type of feeder hopper loudspeaker form, the feed opening is the toper setting. The feed hopper of this structure is convenient for empty the material, and conical feed opening is convenient for discharge the material is whole simultaneously.
Above-mentioned technical scheme can find out, the utility model discloses following beneficial effect has: even formula granulation machine that sways sets up transverse vibration's screen cloth under the discharge gate of granulation machine, can carry out the secondary to the granule through the filter screen and divide the sieve to obtain the more even granule of granule, when the production effect is guaranteed to the granulation machine of this structure, increase production efficiency, can realize the screening of material when the ejection of compact, need not post treatment, further improve production efficiency, overall structure reasonable in design, convenient to use, the maintenance of being convenient for.
Drawings
Fig. 1 is a schematic structural view of a swing type granulator for uniform granulation according to the present invention;
fig. 2 is a front view of the swing type granulation machine for uniform granulation of the present invention;
fig. 3 is a schematic view of a partial structure of the transverse vibration driving assembly of the present invention.
In the figure: base 1, frame 2, drive assembly 3, stirring driving motor 31, drive wheel 32, gear belt 33, follow driving wheel 34, stirring driving motor fixing base 35, feeder hopper 4, feed opening 5, support frame 6, filter screen tightening valve 61, filter screen 7, stirring subassembly 8, stirring pivot 81, stirring connecting rod 82, stirring rod 83, transverse vibration drive assembly 9, vertical support plate 91, transverse vibration driving motor 92, eccentric wheel 93, connecting plate 94, transverse vibration screen cloth 10, articulated connecting seat 101, slider 102, transverse vibration screen cloth support frame 11, slide rail 111, storage box 112.
Detailed Description
Reference will now be made in detail to embodiments of the present invention, examples of which are illustrated in the accompanying drawings, wherein like reference numerals refer to the same or similar elements or elements having the same or similar function throughout. The embodiments described below with reference to the drawings are exemplary and intended to be used for explaining the present invention, and should not be construed as limiting the present invention.
In the description of the present invention, it is to be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "clockwise", "counterclockwise" and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and to simplify the description, but do not indicate or imply that the device or element referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore should not be construed as limiting the present invention.
Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of the present invention, unless otherwise specified, "a plurality" means two or more unless explicitly defined otherwise.
In the present invention, unless otherwise expressly specified or limited, the terms "mounted," "connected," and "fixed" are to be construed broadly and may, for example, be fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present invention can be understood according to specific situations by those skilled in the art.
In the present disclosure, unless expressly stated or limited otherwise, the first feature "on" or "under" the second feature may comprise direct contact between the first and second features, or may comprise contact between the first and second features not directly. Also, the first feature being "on," "above" and "over" the second feature includes the first feature being directly on and obliquely above the second feature, or merely indicating that the first feature is at a higher level than the second feature. A first feature being "under," "below," and "beneath" a second feature includes the first feature being directly under and obliquely below the second feature, or simply meaning that the first feature is at a lesser elevation than the second feature.
Examples
The even oscillating granulator of pelletization as shown in fig. 1-3 comprises a base 1, a frame 2, a driving component 3, a feed hopper 4, a feed opening 5, a support frame 6, a filter screen 7, a stirring component 8, a transverse vibration driving component 9, a transverse vibration screen 10 and a transverse vibration screen support frame 11, wherein the frame 2, the driving component 3, the transverse vibration driving component 9 and the transverse vibration screen support frame 11 are all fixedly arranged on the base 1, the base 1 and the frame 2 are arranged in an "L" shape, the driving component 3 is positioned in a space covered by the frame 2, the driving component 3 is connected with the stirring component 8, the support frame 6 is fixedly arranged on the outer wall of the frame 2, the filter screen 7 is arranged in the support frame 6, the feed hopper 4 and the feed opening 5 are respectively arranged at the upper and lower end parts of the support frame 6, the stirring component 8 is positioned in an area surrounded by the filter screen 7, the transverse vibration drive assembly 9 is connected with a transverse vibration screen 10, the transverse vibration screen 10 is connected with a transverse vibration screen support frame 11 in a sliding mode, the transverse vibration screen 10 is located under the feed opening 5, and the bottom of the transverse vibration screen 10 is a screen.
Wherein, drive assembly 3 includes stirring driving motor 31, action wheel 32, gear belt 33, follows driving wheel 34 and stirring driving motor fixing base 35, stirring driving motor fixing base 35 is fixed to be set up on base 1, stirring driving motor 31 is fixed to be set up on stirring driving motor fixing base 35 to stirring driving motor 31 and action wheel 32 are connected, action wheel 32 passes through gear belt 33 and is connected from driving wheel 34, follow driving wheel 34 and stirring subassembly 8 and connect.
In addition, the stirring assembly 8 comprises a stirring rotating shaft 81, a group of stirring connecting rods 82 and a group of stirring rods 83, wherein the stirring rotating shaft 81 is connected with the driven wheel 34, the stirring connecting rods 82 are arranged between the stirring rotating shaft 81 and the stirring rods 83, the group of stirring rods 83 are arranged in an annular array mode by taking the stirring rotating shaft 81 as a center, and the cross section of each stirring rod 83 is triangular.
And thirdly, two filter screen tightening valves 61 are symmetrically arranged on the support frame 6, and two ends of the filter screen 7 are respectively connected with the two filter screen tightening valves 61. The utility model discloses a structure that the filter screen tightens up valve 61 belongs to prior art in swaing formula granulation machine, for example granted the patent: application No.: 201820467869.0, patent name: the structure of a ratchet wheel and a pawl in the [0034] th section in the swing type granulator; application No.: 201821600113.5, patent name: roll up the screen pipe structure in the formula granulation machine that sways, all can refer to and tighten up valve 61 as the filter screen in this patent for adjust the length and the radian of filter screen 7.
In addition, the transverse vibration driving assembly 9 includes a vertical supporting plate 91, a transverse vibration driving motor 92, an eccentric 93, and a connecting plate 94, the vertical supporting plate 91 is fixedly disposed on the base 1 by bolts, the transverse vibration driving motor 92 is fixedly disposed on the vertical supporting plate 91, and the transverse vibration driving motor 92 is connected to the eccentric 93, one end of the connecting plate 94 is hinged to the eccentric 93, and the other end of the connecting plate 94 is hinged to the transverse vibration screen 10. The side wall of the transverse vibrating screen 10 near one end of the vertical support plate 91 is provided with a hinged connecting seat 101, and the hinged connecting seat 101 is hinged with one end of the connecting plate 94. The cross-section of the transverse vibration screen support frame 11 is U-shaped, the upper end of the transverse vibration screen support frame 11 is in an open shape, two slide rails 111 are symmetrically arranged on two opposite inner walls of the transverse vibration screen support frame 11, sliders 102 are symmetrically arranged on the inner walls, close to two sides of the transverse vibration screen support frame 11, of the transverse vibration screen 10, and the sliders 102 are connected with the slide rails 111 in a sliding mode. The bottom plate of the transverse vibrating screen support frame 11 is provided with a storage box 112, and the storage box 112 is positioned right below the transverse vibrating screen 10. Feeder hopper 4 is the flaring type of horn shape, feed opening 5 is the toper setting.
The utility model discloses an even operating principle who sways formula granulation machine of pelletization does:
pour into the material from feeder hopper 4, the material falls into on filter screen 7, start drive assembly 3 this moment, it rotates to drive stirring pivot 81, stirring pivot 81 rotates the in-process, the material in a set of stirring rod 83 constantly stirs filter screen 7, make the granule of the mesh of compound filter screen 7 fall into transverse vibration screen cloth 10, the mesh size of transverse vibration screen cloth 10 is less than the mesh size of filter screen 7, under transverse vibration drive assembly 9's drive, transverse vibration screen cloth 10 is reciprocal horizontal transverse vibration of doing on transverse vibration screen cloth support frame 11, thereby obtain the even granule of granule further.
The foregoing is only a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, a plurality of modifications can be made without departing from the principles of the present invention, and these modifications should also be regarded as the protection scope of the present invention.

Claims (10)

1. The utility model provides a even formula granulation machine that sways of pelletization which characterized in that: comprises a base (1), a frame (2), a driving component (3), a feed hopper (4), a feed opening (5), a support frame (6), a filter screen (7), a stirring component (8), a transverse vibration driving component (9), a transverse vibration screen (10) and a transverse vibration screen support frame (11), wherein the frame (2), the driving component (3), the transverse vibration driving component (9) and the transverse vibration screen support frame (11) are all fixedly arranged on the base (1), the driving component (3) is positioned in a space covered by the frame (2), the driving component (3) is connected with the stirring component (8), the support frame (6) is fixedly arranged on the outer wall of the frame (2), the filter screen (7) is arranged in the support frame (6), the feed hopper (4) and the feed opening (5) are respectively arranged at the upper end part and the lower end part of the support frame (6), stirring subassembly (8) are located filter screen (7) and surround the region in, transverse vibration drive assembly (9) and transverse vibration screen cloth (10) are connected, transverse vibration screen cloth (10) and transverse vibration screen cloth support frame (11) sliding connection, transverse vibration screen cloth (10) are located feed opening (5) under to the bottom of transverse vibration screen cloth (10) is the screen cloth.
2. The uniform granulation oscillating granulator of claim 1 wherein: the base (1) and the frame (2) are arranged in an L shape.
3. The uniform granulation oscillating granulator of claim 1 wherein: drive assembly (3) are including stirring driving motor (31), action wheel (32), gear area (33), follow driving wheel (34) and stirring driving motor fixing base (35), stirring driving motor fixing base (35) is fixed to be set up on base (1), stirring driving motor (31) is fixed to be set up on stirring driving motor fixing base (35) to stirring driving motor (31) and action wheel (32) are connected, action wheel (32) are connected through gear area (33) and follow driving wheel (34), follow driving wheel (34) and stirring subassembly (8) and connect.
4. The uniform-granulating oscillating granulator of claim 3, wherein: stirring subassembly (8) are including stirring pivot (81), a set of stirring connecting rod (82) and a set of stirring rod (83), stirring pivot (81) are connected with from driving wheel (34), stirring connecting rod (82) set up between stirring pivot (81) and stirring rod (83), a set of stirring rod (83) use stirring pivot (81) to set up according to annular array's mode as the center, the cross-section of stirring rod (83) is triangle-shaped.
5. The uniform granulation oscillating granulator of claim 1 wherein: the filter screen tightening valve is characterized in that two filter screen tightening valves (61) are symmetrically arranged on the support frame (6), and two ends of the filter screen (7) are respectively connected with the two filter screen tightening valves (61).
6. The uniform granulation oscillating granulator of claim 1 wherein: the transverse vibration driving assembly (9) comprises a vertical supporting plate (91), a transverse vibration driving motor (92), an eccentric wheel (93) and a connecting plate (94), wherein the vertical supporting plate (91) is fixedly arranged on the base (1) through bolts, the transverse vibration driving motor (92) is fixedly arranged on the vertical supporting plate (91), the transverse vibration driving motor (92) is connected with the eccentric wheel (93), one end of the connecting plate (94) is hinged to the eccentric wheel (93), and the other end of the connecting plate (94) is hinged to the transverse vibration screen (10).
7. The uniform-granulating oscillating granulator of claim 6, wherein: the lateral wall of one end, close to the vertical support plate (91), of the transverse vibrating screen (10) is provided with a hinged connecting seat (101), and the hinged connecting seat (101) is hinged to one end of the connecting plate (94).
8. The uniform-granulating oscillating granulator of claim 7, wherein: the cross-section of transverse vibration screen cloth support frame (11) is the U type, the upper end of transverse vibration screen cloth support frame (11) is the opening form to two relative inner walls of transverse vibration screen cloth support frame (11) are gone up the symmetry and are equipped with two slide rails (111), the symmetry is equipped with slider (102) on the inner wall that transverse vibration screen cloth (10) are close to transverse vibration screen cloth support frame (11) both sides, slider (102) and slide rail (111) sliding connection.
9. The uniform granulation oscillating granulator of claim 8 wherein: and a storage box (112) is arranged on the bottom plate of the transverse vibrating screen support frame (11), and the storage box (112) is positioned under the transverse vibrating screen (10).
10. The uniform granulation oscillating granulator of claim 1 wherein: feeder hopper (4) are the flaring type of loudspeaker form, feed opening (5) are the toper setting.
CN202020289239.6U 2020-03-11 2020-03-11 Even formula granulation machine that sways of pelletization Active CN211800646U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202020289239.6U CN211800646U (en) 2020-03-11 2020-03-11 Even formula granulation machine that sways of pelletization

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202020289239.6U CN211800646U (en) 2020-03-11 2020-03-11 Even formula granulation machine that sways of pelletization

Publications (1)

Publication Number Publication Date
CN211800646U true CN211800646U (en) 2020-10-30

Family

ID=73009002

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202020289239.6U Active CN211800646U (en) 2020-03-11 2020-03-11 Even formula granulation machine that sways of pelletization

Country Status (1)

Country Link
CN (1) CN211800646U (en)

Similar Documents

Publication Publication Date Title
CN210993917U (en) Stirring and mixing mechanism of grinding and mixing device for production of raw material medicines
CN114273224B (en) Wet soft viscidity granule material letter sorting equipment
CN203886787U (en) Particle material screening machine
CN211800646U (en) Even formula granulation machine that sways of pelletization
CN212911629U (en) Circulating pelletization device of fodder three-layer
CN217410676U (en) Prevent that sieve mesh blocks up and formula granulation machine that sways of autofilter granule
CN109999721A (en) Vanadium slag prilling granulator
CN214438820U (en) Swing type granulator
CN215693769U (en) High-efficient pair roller granulator
CN211027061U (en) Pesticide powder sieving machine
CN213727647U (en) Ecological building materials batching filter equipment
CN212396849U (en) Poultry is with fodder preparation raw materials reducing mechanism
CN211070001U (en) Aggregate preparation facilities is used in cable material production
CN210229877U (en) Swing type granulating machine
CN210411449U (en) Novel fertilizer raw materials screening device
CN220835427U (en) Feeding device of boiling granulating dryer
CN220759161U (en) Granulating device for granulating potash fertilizer particles
CN212092138U (en) Formula granulation machine sways with screening function
CN215388996U (en) Can distinguish mixer of granule material and powder
CN220423069U (en) Biological feed production equipment
CN217490759U (en) Oscillating granulator for pharmacy
CN115889372B (en) Raw material processing system in rotary drum granulation system
CN214486794U (en) Novel dry-process rolling granulator
CN217893273U (en) Collecting device for dry powder extinguishing agent
CN219072870U (en) Granulating machine for spraying granulating compound fertilizer

Legal Events

Date Code Title Description
GR01 Patent grant
GR01 Patent grant
CP01 Change in the name or title of a patent holder

Address after: 225300 No.1, South Batang Road, China medicine city, Taizhou City, Jiangsu Province

Patentee after: Jiangsu Changtai Pharmaceutical Co.,Ltd.

Address before: 225300 No.1, South Batang Road, China medicine city, Taizhou City, Jiangsu Province

Patentee before: JIANG SU PHARMAMAXCORP Co.,Ltd.

CP01 Change in the name or title of a patent holder