CN211627579U - Early detection kit for diabetic nephropathy based on biomarkers - Google Patents
Early detection kit for diabetic nephropathy based on biomarkers Download PDFInfo
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- CN211627579U CN211627579U CN202020339914.1U CN202020339914U CN211627579U CN 211627579 U CN211627579 U CN 211627579U CN 202020339914 U CN202020339914 U CN 202020339914U CN 211627579 U CN211627579 U CN 211627579U
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- 238000001514 detection method Methods 0.000 title claims abstract description 48
- 208000007342 Diabetic Nephropathies Diseases 0.000 title claims abstract description 20
- 208000033679 diabetic kidney disease Diseases 0.000 title claims abstract description 20
- 239000000090 biomarker Substances 0.000 title claims abstract description 16
- 239000003153 chemical reaction reagent Substances 0.000 claims abstract description 62
- 238000005538 encapsulation Methods 0.000 claims abstract description 37
- 238000007689 inspection Methods 0.000 claims abstract description 20
- 239000011521 glass Substances 0.000 claims abstract description 10
- 230000001681 protective effect Effects 0.000 claims abstract description 8
- 238000002474 experimental method Methods 0.000 claims description 17
- 239000010902 straw Substances 0.000 claims description 14
- 238000004806 packaging method and process Methods 0.000 claims description 6
- 238000004659 sterilization and disinfection Methods 0.000 claims description 6
- 238000005070 sampling Methods 0.000 claims description 5
- 238000000926 separation method Methods 0.000 claims 3
- 230000007306 turnover Effects 0.000 claims 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract description 3
- 208000017169 kidney disease Diseases 0.000 abstract description 2
- 239000000523 sample Substances 0.000 description 13
- 238000000034 method Methods 0.000 description 4
- 238000013399 early diagnosis Methods 0.000 description 2
- 239000012535 impurity Substances 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 208000020832 chronic kidney disease Diseases 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 239000012470 diluted sample Substances 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 208000028208 end stage renal disease Diseases 0.000 description 1
- 201000000523 end stage renal failure Diseases 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 238000011862 kidney biopsy Methods 0.000 description 1
- 239000003550 marker Substances 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 208000032598 susceptibility microvascular complications of diabetes Diseases 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 229920001169 thermoplastic Polymers 0.000 description 1
- 239000004416 thermosoftening plastic Substances 0.000 description 1
- 230000000472 traumatic effect Effects 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
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Abstract
The utility model discloses a diabetes and nephropathy early detection kit based on biomarkers, which comprises a kit body, a flip cover, a reagent collecting and releasing piece, a glass protective cover and a detection groove, wherein the flip cover is hinged on the side wall of the kit body, the bottom wall of the flip cover is arranged in an inwards concave cambered surface structure, the detection groove is arranged on the upper wall of the kit body, the glass protective cover can be rotatably arranged on the detection groove, and the reagent collecting and releasing piece is arranged in the kit body and is arranged at the side of the detection groove; the reagent receive and releases the piece and includes reagent encapsulation pipe and reagent encapsulation pipe standing groove, reagent encapsulation pipe standing groove is located in the reagent box and is located the inspection groove side, the reagent encapsulation pipe slidable is located in the reagent encapsulation pipe standing groove, reagent encapsulation pipe tip is equipped with the heat and moulds the seal. The utility model belongs to the technical field of biological detection, specifically indicate a can prevent the interference, guarantee the reliable early detection kit of diabetic nephropathy based on biomarker of analysis result.
Description
Technical Field
The utility model belongs to the technical field of biological detection, specifically indicate early detection kit of diabetic nephropathy based on biomarker.
Background
Diabetic nephropathy is one of the most serious chronic microvascular complications of diabetes, and ultimately leads to end-stage renal failure, which is the leading cause of death in diabetic patients. Although the kidney biopsy technique can assist the early diagnosis of clinical diabetic nephropathy, the technique has high traumatic property, can cause complications after operation, has high technical difficulty and cannot be used as a routine item for the examination of diabetic nephropathy patients. Often when clinically diagnosed, diabetic nephropathy patients miss the best opportunity for treatment, causing the disease to worsen dramatically and irreversibly. Therefore, the positive search for the diabetic nephropathy early diagnosis marker and the detection reagent tube kit thereof and the early intervention have important practical significance.
SUMMERY OF THE UTILITY MODEL
In order to solve the problem, the utility model provides a can prevent the interference, guarantee the reliable early detection kit of diabetic nephropathy based on biomarker of analysis result, can be used to distinguish early diabetic nephropathy to intervene the treatment as early as possible.
In order to realize the above functions, the utility model discloses the technical scheme who takes as follows: the early detection kit for the diabetic nephropathy based on the biomarker comprises a kit body, a flip cover, a reagent collecting and releasing piece, a glass protective cover and a detection groove, wherein the flip cover is hinged to the side wall of the kit body, the bottom wall of the flip cover is of an inwards concave cambered surface structure, the detection groove is formed in the upper wall of the kit body, the glass protective cover is rotatably arranged on the detection groove and used for covering the detection groove and keeping the interior of the detection groove clean, and the reagent collecting and releasing piece is arranged in the kit body and arranged on the side of the detection groove and used for storing a reagent for detection; the reagent receive and releases the piece and includes reagent encapsulation pipe and reagent encapsulation pipe standing groove, reagent encapsulation pipe standing groove is located in the reagent box and is located the inspection groove side, the reagent encapsulation pipe slidable is located in the reagent encapsulation pipe standing groove, reagent encapsulation pipe tip is equipped with the heat and moulds the seal, can make reagent encapsulation pipe sealed, prevents that reagent from receiving the pollution.
Further, be equipped with the division board in the inspection groove, the division board has the rake structure setting of diaphragm for the middle part, the division board will inspect groove evenly divided multiunit analysis and detection groove and multiunit experiment contrast groove, analysis and detection groove sets up with experiment contrast groove one-to-one, carries out sample analysis in analysis and detection inslot, carries out the contrast experiment that does not add the sample in experiment contrast inslot to observe better, improve the detection accuracy, analysis and detection groove and experiment contrast tank bottom all are equipped with the broken wall awl, seal with breaking reagent encapsulation pipe heat plastic, make the intraductal reagent of reagent encapsulation flow.
Further, reagent encapsulation pipe standing groove is linear evenly to be equipped with the multiunit, reagent encapsulation pipe standing groove linear arrangement's central blank department is equipped with the sample straw standing groove, the sample straw standing groove is equipped with the sample straw, the sample straw is disposable for the urine after the extraction dilutes detects.
Further, embedded disinfection piece encapsulation bag that is equipped with of flip inner wall, disinfection piece in the disinfection piece encapsulation bag can be used to the cleanness on reagent encapsulation pipe surface, prevents during the broken wall impurity sneaks into the reagent.
Further, be equipped with the buckle on the outer wall of the opposition side of flip and the articulated side of kit body, be equipped with the fixture block on the outer wall of the opposition side of kit body and the articulated side of flip, the buckle can closely be buckled on with the fixture block, realizes the sealed of kit, avoids being infected with external bacterium.
The utility model adopts the above structure to gain beneficial effect as follows: the utility model provides a diabetes and nephropathy early detection kit based on biomarkers, which has simple structure, reasonable design and convenient carrying, and can break the reagent packaging tube without the help of external tools, so that the internal reagent flows out, and the external bacterial pollution is avoided; the glass protective cover is arranged, so that the interior of the inspection groove is further kept clean, and the interference of impurities during inspection is reduced; the division board divides the inspection groove into analysis and detection groove and experiment contrast groove, and the application of disposable sample straw avoids the sample alternately simultaneously, therefore can distinguish the difference of the phenomenon that appears in the testing process better, improves the detection accuracy.
Drawings
FIG. 1 is a schematic diagram of the overall structure of the biomarker-based diabetic nephropathy early detection kit of the present invention;
FIG. 2 is a perspective view of the reagent packaging tube of the early stage detection kit base for diabetic nephropathy based on biomarkers of the present invention.
Wherein, 1, kit body, 2, flip, 3, reagent receive and releases the piece, 4, glass protective cover, 5, inspection groove, 6, reagent encapsulation pipe, 7, reagent encapsulation pipe standing groove, 8, thermoplastic seal, 9, division board, 10, broken wall awl, 11, sample straw standing groove, 12, disinfection piece encapsulation bag, 13, buckle, 14, fixture block, 15, analysis and detection groove, 16, experiment contrast groove.
Detailed Description
The technical solution of the present invention will be described in further detail with reference to the following embodiments, and the technical features or the connection relations of the present invention, which are not described in detail, are the prior art adopted.
In the description of the present invention, it is to be understood that the terms "longitudinal", "lateral", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", and the like, indicate orientations or positional relationships based on the orientations or positional relationships illustrated in the drawings, and are used for convenience in describing the present invention and simplifying the description, but do not indicate or imply that the device or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus should not be construed as limiting the present invention.
The present invention will be described in further detail with reference to the accompanying drawings.
As shown in fig. 1-2, the utility model discloses early detection kit for diabetic nephropathy based on biomarker, including kit body 1, flip 2, reagent receiving and releasing piece 3, glass protection cover 4 and inspection groove 5, flip 2 articulates in kit body 1 lateral wall, flip 2 bottom wall is the setting of indent cambered surface structure, inspection groove 5 locates kit body 1 upper wall, glass protection cover 4 is rotatable to be located on inspection groove 5, reagent receiving and releasing piece 3 locates in kit body 1 and locates the side of inspection groove 5; reagent receive and releases 3 and include reagent encapsulation pipe 6 and reagent encapsulation pipe standing groove 7, reagent encapsulation pipe standing groove 7 is located in the reagent box and is located 5 sides of inspection groove, reagent encapsulation pipe 6 slidable locates in reagent encapsulation pipe standing groove 7, 6 tip of reagent encapsulation pipe are equipped with the heat and seal 8.
Specifically, be equipped with division board 9 in the inspection groove 5, division board 9 has the rake structure setting of diaphragm for the middle part, division board 9 will inspect groove 5 evenly divided multiunit analysis and detection groove 15 and multiunit experiment contrast groove 16, analysis and detection groove 15 and the setting of experiment contrast groove 16 one-to-one, analysis and detection groove 15 and experiment contrast groove 16 bottom all are equipped with broken wall awl 10.
Specifically, reagent encapsulation pipe standing groove 7 is linear evenly to be equipped with the multiunit, reagent encapsulation pipe standing groove 7 linear arrangement's central blank department is equipped with sample straw 17 standing groove 11, sample straw 17 standing groove is equipped with sample straw 17, sample straw 17 is disposable.
Specifically, a disinfection sheet packaging bag 12 is embedded in the inner wall of the flip cover 2.
Specifically, be equipped with buckle 13 on the outer wall of the opposition side of flip 2 and the articulated side of kit body 1, be equipped with fixture block 14 on the outer wall of the opposition side of the articulated side of kit body 1 and flip 2, buckle 13 can closely buckle on with fixture block 14.
When the method is used, the reagents for detection are respectively poured into the analysis detection groove 15 and the experiment contrast groove 16, the diluted samples are sucked by the sampling tube and dripped into the analysis detection groove 15, blank experiments are carried out on the samples which are not added into the experiment contrast groove 16, and after a certain period of time, the samples in the analysis detection groove 15 and the experiment contrast groove 16 are analyzed and detected through comparison.
The present invention and the embodiments thereof have been described above, but the description is not limited thereto, and the embodiment shown in the drawings is only one of the embodiments of the present invention, and the actual structure is not limited thereto. In summary, those skilled in the art should understand that they should not be limited to the embodiments described above, and that they can design the similar structure and embodiments without departing from the spirit of the invention.
Claims (5)
1. Early detection kit of diabetic nephropathy based on biomarker which characterized in that: the kit comprises a kit body, a flip cover, a reagent collecting and releasing piece, a glass protective cover and an inspection groove, wherein the flip cover is hinged to the side wall of the kit body, the bottom wall of the flip cover is of an inwards concave cambered surface structure, the inspection groove is formed in the upper wall of the kit body, the glass protective cover is rotatably arranged on the inspection groove, and the reagent collecting and releasing piece is arranged in the kit body and is arranged on the side of the inspection groove; the reagent receive and releases the piece and includes reagent encapsulation pipe and reagent encapsulation pipe standing groove, reagent encapsulation pipe standing groove is located in the reagent box and is located the inspection groove side, the reagent encapsulation pipe slidable is located in the reagent encapsulation pipe standing groove, reagent encapsulation pipe tip is equipped with the heat and moulds the seal.
2. The biomarker-based early detection kit for diabetic nephropathy according to claim 1, characterized in that: the inspection groove is internally provided with a separation plate, the separation plate is a rake structure with a transverse plate at the middle part, the separation plate uniformly divides the inspection groove into a plurality of groups of analysis detection grooves and a plurality of groups of experiment control grooves, the analysis detection grooves are in one-to-one correspondence with the experiment control grooves, and the analysis detection grooves and the experiment control groove bottoms are all provided with wall breaking cones.
3. The biomarker-based early detection kit for diabetic nephropathy according to claim 1, characterized in that: the reagent packaging tube placing grooves are linearly and uniformly provided with a plurality of groups, the central blank positions of the reagent packaging tube placing grooves which are linearly arranged are provided with sampling straw placing grooves, the sampling straw placing grooves are provided with sampling straws, and the sampling straws are disposable articles.
4. The biomarker-based early detection kit for diabetic nephropathy according to claim 1, characterized in that: a disinfection sheet packaging bag is embedded in the inner wall of the turnover cover.
5. The biomarker-based early detection kit for diabetic nephropathy according to claim 1, characterized in that: the kit comprises a kit body and is characterized in that a buckle is arranged on the outer wall of the opposite side of the hinged side of the flip cover and the kit body, a clamping block is arranged on the outer wall of the opposite side of the hinged side of the kit body and the flip cover, and the buckle can be tightly buckled with the clamping block.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202020339914.1U CN211627579U (en) | 2020-03-18 | 2020-03-18 | Early detection kit for diabetic nephropathy based on biomarkers |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202020339914.1U CN211627579U (en) | 2020-03-18 | 2020-03-18 | Early detection kit for diabetic nephropathy based on biomarkers |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN211627579U true CN211627579U (en) | 2020-10-02 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202020339914.1U Expired - Fee Related CN211627579U (en) | 2020-03-18 | 2020-03-18 | Early detection kit for diabetic nephropathy based on biomarkers |
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| CN (1) | CN211627579U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112903988A (en) * | 2021-01-25 | 2021-06-04 | 贵州医科大学附属医院 | Diabetic nephropathy treatment marker supar detection device |
-
2020
- 2020-03-18 CN CN202020339914.1U patent/CN211627579U/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112903988A (en) * | 2021-01-25 | 2021-06-04 | 贵州医科大学附属医院 | Diabetic nephropathy treatment marker supar detection device |
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| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20201002 |
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| CF01 | Termination of patent right due to non-payment of annual fee |