CN211560072U - Cold and hot plate pain measuring instrument for animal pharmacological experiment - Google Patents
Cold and hot plate pain measuring instrument for animal pharmacological experiment Download PDFInfo
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- CN211560072U CN211560072U CN202020091874.3U CN202020091874U CN211560072U CN 211560072 U CN211560072 U CN 211560072U CN 202020091874 U CN202020091874 U CN 202020091874U CN 211560072 U CN211560072 U CN 211560072U
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Abstract
A cold and hot plate pain measuring instrument for animal pharmacological experiments comprises a shell, a refrigerating sheet, a heating sheet, a box body bottom plate, a box body partition plate, a box body cover, a pushing device and an observation box; the shell is a cuboid shell, the interior of the shell is divided into an upper part and a lower part through a box body bottom plate, the upper part is an observation box, the lower part is a pushing device, and a refrigerating sheet and a heating sheet are mounted on the pushing device; the pushing device comprises a disc, a push rod and a rotating shaft; the rotating shaft is coaxially and fixedly connected with the disc, and the tail end of the rotating shaft is bent; one end of the push rod is hinged with the circumference of the disc, the other end of the push rod is hinged with the heating sheet or the refrigerating sheet, and the rotating shaft is rotated to drive the push rod to push the heating sheet or the refrigerating sheet to move up and down; when moving upwards, the box body can be contacted with the bottom plate of the box body; the observation box is internally provided with two box body partition plates which can move back and forth in the box body, the white mouse is placed in the observation chamber, and the back and forth movement of the white mouse is controlled by moving the box body partition plates; the upper side of the box body is provided with a box body cover.
Description
Technical Field
The utility model relates to an animal experiment equipment technical field, concretely relates to cold and hot board pain measuring instrument for animal pharmacology experiments.
Background
At present, screening experiment methods for acute pain analgesic drugs are carried out by using a cold and hot plate experiment device, a rat plantar tenderness irradiation experiment is carried out, different reactions of cold and hot touch of a rat are observed, and two effects of acting the analgesic drugs on physiological pain and pathological pain are obtained; however, in the existing pain measuring instrument, two mice are respectively placed in a cold-touching chamber and a hot-touching chamber to observe the reaction of the mice, and different organisms have individual differences, so that the experimental result is unreliable; some cold and hot pain measuring instruments adopt a box body to heat or refrigerate respectively, and this kind of cold and hot pain measuring instrument temperature has a process of intensification or cooling, and at this in-process, the mouse can produce physiological reaction, and the mouse adapts to new environment gradually, also causes the experimental result inaccurate.
SUMMERY OF THE UTILITY MODEL
In order to solve the problems, the utility model designs a cold and hot plate pain measuring instrument for animal pharmacology experiments; when this cold and hot board pain measuring appearance measures the mouse, the mouse is contact in the twinkling of an eye, does not have environmental adaptation time, carries out cold and contact heat to same mouse and surveys pain and detect, and measurement experiment result is accurate.
In order to realize the technical purpose, reach above-mentioned technological effect, the utility model discloses a realize through following technical scheme:
a cold and hot plate pain measuring instrument for animal pharmacological experiments comprises a shell, a refrigerating sheet, a heating sheet, a box body bottom plate, a box body partition plate, a box body cover, a pushing device and an observation box; the shell is a cuboid shell, the interior of the shell is divided into an upper part and a lower part through a box body bottom plate, the upper half part of the shell is an observation box, the lower half part of the shell is provided with two pushing devices, and the pushing devices are respectively provided with a refrigerating sheet and a heating sheet;
the pushing device comprises a disc, a push rod and a rotating shaft; the rotating shaft is coaxially and fixedly connected with the disc, and the tail end of the rotating shaft is bent, so that the rotating shaft can be conveniently rotated; one end of the push rod is hinged with the circumference of the disc, the other end of the push rod is hinged with the heating sheet or the refrigerating sheet, and the rotating shaft is rotated to drive the push rod to push the heating sheet or the refrigerating sheet to move up and down; can contact the bottom plate of the box body when moving upwards.
The observation box is internally provided with two box body partition plates which can move back and forth in the box body, the white mouse is placed between the two box body partition plates, and the back and forth movement of the white mouse is controlled by moving the box body partition plates; the upper side of the box body is provided with a box body cover.
Furthermore, the side surface of the observation box is provided with a rectangular groove, the box body partition plate is connected with a handle through the rectangular groove, and the box body partition plate is moved through the handle.
Furthermore, the bottom plate of the box body is of a net structure, so that the refrigerating sheet or the heating sheet can effectively contact with the mouse.
Furthermore, the refrigerating piece is a semiconductor refrigerating piece.
Further, the heating plate is a carbon fiber heating plate.
The utility model has the advantages that: when this cold and hot board pain measuring appearance measures the mouse, adopt and remove heating plate or refrigeration piece contact the mouse in the twinkling of an eye, keep apart the mouse through the box baffle, the activity space of mouse is easily controlled, and the mouse does not have cold or hot environment adaptation time, carries out cold and contact heat to same mouse and surveys the pain and detect, and measurement experiment result is accurate.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings used in the description of the embodiments will be briefly introduced below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art that other drawings can be obtained according to these drawings without creative efforts.
FIG. 1 is a schematic sectional view of the cold and hot plate pain measuring instrument for animal pharmacological experiments;
fig. 2 is a left view structure schematic diagram of a cold and hot plate pain measuring instrument for animal pharmacology experiments.
In the drawings, the components represented by the respective reference numerals are listed below:
the refrigerator comprises a shell 1, a refrigerating sheet 2, a heating sheet 3, a box bottom plate 4, a box partition plate 5, a handle 501, a box cover 6, a pushing device 7, a disc 701, a push rod 702, a rotating shaft 703 and an observation box 8.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by a person of ordinary skill in the art without creative efforts belong to the protection scope of the present invention.
Referring to fig. 1-2, the cold and hot plate pain measuring instrument for animal pharmacological experiments comprises a shell 1, a refrigerating plate 2, a heating plate 3, a box body bottom plate 4, a box body partition plate 5, a box body cover 6, a pushing device 7 and an observation box 8; the shell 1 is a cuboid shell, the interior of the shell is divided into an upper part and a lower part through a box body bottom plate 4, the upper half part of the shell 1 is an observation box 8, the lower half part of the shell is provided with two pushing devices 7, and the pushing devices 7 are respectively provided with a refrigerating sheet 2 and a heating sheet 3;
the pushing device 7 comprises a disc 701, a push rod 702 and a rotating shaft 703; the rotating shaft 703 is coaxially and fixedly connected with the disc 701, and the tail end of the rotating shaft 703 is bent to facilitate the rotation of the rotating shaft 703; one end of the push rod 702 is hinged with the circumference of the disc 701, the other end of the push rod 702 is hinged with the heating sheet 3 or the refrigerating sheet 2, and the rotating shaft 703 drives the push rod 702 to push the heating sheet 3 or the refrigerating sheet 2 to move up and down; when moving upwards, the box bottom plate 4 can be contacted.
The observation box 8 is internally provided with two box body partition plates 5, the box body partition plates 5 can move back and forth in the box body, the white mouse is placed between the two box body partition plates 5, and the back and forth movement of the white mouse is controlled by moving the box body partition plates 5; the upper side of the box body is provided with a box body cover 6.
Wherein, 8 sides of observation box have a rectangle groove, box baffle 5 be connected with handle 501 through rectangle groove, remove box baffle 5 through handle 501.
The bottom plate 4 of the box body is of a net structure, so that the refrigerating sheet 2 or the heating sheet 3 can effectively contact with a mouse.
The refrigerating plate 2 is a semiconductor refrigerating plate.
Wherein, the heating plate 3 is a carbon fiber heating plate.
In specific implementation, two box body partition plates 5 are respectively arranged at two sides of an observation box 8, a box body cover 6 is opened, a white mouse is placed, the box body cover 6 is covered, the box body partition plates 5 are moved, the white mouse is moved to the heating plate side 3, a rotating shaft 703 of a pushing device 7 is rotated, the heating plate 3 is made to contact feet of the white mouse, and the reaction of the white mouse is observed; and then the mice are moved to the side of the refrigerating plate 2 by moving the box body partition plate 5, the rotating shaft 703 of the pushing device 7 is rotated, the refrigerating plate 2 is made to contact the feet of the mice, the reaction of the mice is watched, the mice are instantaneously contacted with the same mice, the mice have no environmental adaptation time, and the measurement effect is accurate.
In the description herein, references to the description of "one embodiment," "an example," "a specific example," etc., mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the invention. In this specification, the schematic representations of the terms used above do not necessarily refer to the same embodiment or example.
The preferred embodiments of the present invention disclosed above are intended only to help illustrate the present invention. The preferred embodiments are not intended to be exhaustive or to limit the invention to the precise embodiments disclosed. Obviously, many modifications and variations are possible in light of the above teaching. The present invention is limited only by the claims and their full scope and equivalents.
Claims (5)
1. The cold and hot plate pain measuring instrument for animal pharmacological experiments is characterized by comprising a shell, a refrigerating piece, a heating piece, a box body bottom plate, a box body partition plate, a box body cover, a pushing device and an observation box; the shell is a cuboid shell, the interior of the shell is divided into an upper part and a lower part through a box body bottom plate, the upper half part of the shell is an observation box, the lower half part of the shell is provided with two pushing devices, and the pushing devices are respectively provided with a refrigerating sheet and a heating sheet;
the pushing device comprises a disc, a push rod and a rotating shaft; the rotating shaft is coaxially and fixedly connected with the disc, and the tail end of the rotating shaft is bent; one end of the push rod is hinged with the circumference of the disc, and the other end of the push rod is hinged with the heating sheet or the refrigerating sheet and can contact the bottom plate of the box body when moving upwards;
the observation box is internally provided with two box body partition plates which can move back and forth in the box body; the upper side of the box body is provided with a box body cover.
2. The cold and hot plate pain test instrument for animal pharmacology experiments as claimed in claim 1, wherein the side of the observation box is provided with a rectangular groove, and the box body partition is connected with a handle through the rectangular groove.
3. The cold and hot plate pain test instrument for animal pharmacology experiments as claimed in claim 1, wherein the bottom plate of the box body is provided with a net structure.
4. The cold and hot plate pain test instrument for animal pharmacological experiments, according to claim 1, wherein the refrigeration piece is a semiconductor refrigeration piece.
5. The cold and hot plate pain test instrument for animal pharmacology experiments as claimed in claim 1, wherein the heating plate is a carbon fiber heating plate.
Priority Applications (1)
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CN202020091874.3U CN211560072U (en) | 2020-01-16 | 2020-01-16 | Cold and hot plate pain measuring instrument for animal pharmacological experiment |
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CN202020091874.3U CN211560072U (en) | 2020-01-16 | 2020-01-16 | Cold and hot plate pain measuring instrument for animal pharmacological experiment |
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CN211560072U true CN211560072U (en) | 2020-09-25 |
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CN202020091874.3U Expired - Fee Related CN211560072U (en) | 2020-01-16 | 2020-01-16 | Cold and hot plate pain measuring instrument for animal pharmacological experiment |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114503927A (en) * | 2020-11-17 | 2022-05-17 | 湖南盛世丰花生物科技有限公司 | Multifunctional experimental box for radioorganisms |
-
2020
- 2020-01-16 CN CN202020091874.3U patent/CN211560072U/en not_active Expired - Fee Related
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114503927A (en) * | 2020-11-17 | 2022-05-17 | 湖南盛世丰花生物科技有限公司 | Multifunctional experimental box for radioorganisms |
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Legal Events
Date | Code | Title | Description |
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GR01 | Patent grant | ||
GR01 | Patent grant | ||
CP02 | Change in the address of a patent holder |
Address after: Kunming Medical University, No. 1168, Chunrong West Road, Chenggong District, Kunming City, Yunnan Province Patentee after: KUNMING MEDICAL University Address before: Kunming Medical University, No. 1168, Chunrong West Road, Chenggong District, Qujing City, Yunnan Province, 650500 Patentee before: KUNMING MEDICAL University |
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CP02 | Change in the address of a patent holder | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20200925 Termination date: 20220116 |
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CF01 | Termination of patent right due to non-payment of annual fee |