Multifunctional experimental box for radiobiology
Technical Field
The invention relates to the field of a radiobiological multifunctional experimental box, in particular to a radiobiological multifunctional experimental box.
Background
The radiation oncology subject has developed rapidly in recent years, and the basic and clinical studies related thereto have also developed rapidly. Generally, the verification of the radiobiological results requires biological (animal) experiments to verify. Most commonly, experimental studies are performed by establishing animal models of tumors. In the experiment, the fixation of the experimental object is a problem, and particularly, the fixation of the small animals is a difficult problem. And the research on the biological radiation auxiliary device at home and abroad is always a blank. The irradiation experiment of the common rat and mouse has lower requirements on environment, rat state and the like, and most of people adopt more intuitive, original and rough modes, and can be generally implemented as long as a fixed method capable of meeting the experiment requirements is adopted. Nude mice, in vitro cells and the like have higher requirements on experimental environment. Nude mice are vulnerable to bacterial, viral and fungal infections due to lack of T cells, and only a few mice survive for one month if exposed to the external environment. In radiotherapy experiments of tumor models of nude mice, the nude mice are required to survive for a long time after being irradiated by radioactive rays in order to compare the survival time of the nude mice under different experimental schemes.
Present multi-functional laboratory box of radiobiology is when using, generally adopt to shelve the mouse in the inside of proof box and test, because the inner space of proof box is great, the home range that leads to the mouse has very big area, when staff need control the mouse in the inside active area of proof box, the effect is not good, when carrying out the radiation test to the mouse simultaneously, the mouse excretes unpleasant liquid very easily, lead to the staff when clearing up the liquid, it is very troublesome, consequently, need improve.
Disclosure of Invention
The invention aims to provide a multifunctional experimental box for radiobiology, which solves the problems in the background technology.
In order to achieve the purpose, the invention provides the following technical scheme:
a multifunctional experimental box for radiobiology comprises an experimental box body, wherein sliding grooves are formed in two sides of the interior of the experimental box body, sliding blocks are connected to the interior of the sliding grooves in a sliding mode, the sliding blocks extend to the outer portion of the sliding grooves, a partition plate is fixedly connected to the top of each sliding block, air holes are formed in the partition plate, screw rods are fixedly connected to two sides of the top of each partition plate, a box cover is fixedly connected to the top of the experimental box body, sliding ways are formed in two sides of the interior of the box cover, the screw rods extend to the outer portion of each sliding way, a locking nut is fixedly connected to the outer surface of each screw rod, a connecting block is fixedly connected to one side of the outer surface of the experimental box body, a placing frame is fixedly connected to one side of each connecting block, an oxygen box is movably installed in the placing frame, oxygen is arranged in the oxygen box, an oxygen outlet pipe is fixedly connected to the interior of the oxygen box, the oxygen outlet pipe penetrates through the interior of the experiment box body.
As a further scheme of the invention: the quantity of baffle is two, the quantity of bleeder vent is a plurality of, a plurality of the bleeder vent divide into two sets ofly, and every group the inside at the baffle is seted up with rectangular array's form to the bleeder vent, through the setting of bleeder vent, can make the inside oxygen of experiment box get into the middle part of experiment box through the bleeder vent, prevents that the oxygen deficiency phenomenon from appearing in the mice.
As a still further scheme of the invention: the equal fixedly connected with motor case in both sides of experiment box surface, the inside of motor case is provided with the motor, the output of motor rotates and is connected with motor shaft, motor shaft's one end extends to the inside of experiment box, motor case and experiment box fixed connection to prevent the idle running of motor, staff start motor, make the motor drive motor shaft and rotate.
As a still further scheme of the invention: the one end fixedly connected with cleaning plate of motor shaft, one side fixedly connected with cleaning brush of cleaning plate, just the quantity of cleaning brush is two, when motor shaft is rotating, because cleaning plate and motor shaft fixed connection to drive the cleaning plate and rotate, the cleaning brush will produce the contact with the inner wall of experiment box this moment, thereby scrape the brush through the excrement that the cleaning brush produced little white mouse, and then save the time of the manual clearance excrement of staff, also improved cleaning efficiency simultaneously.
As a still further scheme of the invention: the interior roof fixedly connected with illumination lamp stand of case lid, the inside of illumination lamp stand is provided with the light, and the staff starts the light for the light sends the light, and then the staff of being convenient for in time observes the inside experimental conditions of experiment box.
As a still further scheme of the invention: the positive fixedly connected with gusset plate of experiment box, the cavity has been seted up to the inside of gusset plate, the inside fixedly connected with observation glass of cavity, just the quantity of observation glass is six, the opposite side of experiment box articulates there is the baffle, and observation glass is the transparence to make staff's eyes can see the inside of experiment box clearly, the baffle is articulated mutually with the experiment box, thereby makes the staff open the baffle, throws into the inside of experiment box with the mice.
As a still further scheme of the invention: the bottom of experiment box is provided with the backup pad, the slot has been seted up to the inside of backup pad, the equal fixedly connected with inserted bar in both sides of experiment bottom half, just the inserted bar is pegged graft in the inside of slot, when needs are fixed the experiment box, the staff places the experiment box in the top of backup pad, because the inside of backup pad and the bottom of experiment box are provided with the slot and the inserted bar of mutual adaptation respectively to make the staff peg graft the inside to the slot, and then carry out spacing and restraint to the experiment box in the inside of backup pad, thereby can fix the experiment box, prevent rocking of experiment box.
As a still further scheme of the invention: the quantity of slot is eight, and eight every four slots are a set of, and every group the size of slot two liang, distance homoenergetic, through the setting of eight slots, can make the backup pad can fix two experiment boxes.
Compared with the prior art, the invention has the beneficial effects that:
1. in the invention, through the matching arrangement of the experiment box body, the sliding groove, the sliding block, the partition plate, the air holes, the screw rod, the box cover, the sliding way, the locking nut, the oxygen box and the oxygen outlet pipe, when the device is used, when a worker needs to reduce the moving range of a mouse in the experiment box body, the worker holds the top of the screw rod so as to move the screw rod to the center of the experiment box body, and the partition plate is fixedly connected with the screw rod, so that when the screw rod is displaced, the partition plate can be displaced in the sliding groove through the sliding block, so that under the thrust of the worker, the two partition plates can be displaced along the center of the experiment box body, the experiment box body is further separated into three parts, at the moment, the mouse can only move in the middle of the experiment box body, the moving area of the mouse is further shortened, the device is simple and convenient, after having shortened the active area of mice, the staff wrench movement lock nut for lock nut is to displacement down at the surface of screw rod, thereby contacts with the top of case lid, makes lock nut and case lid produce frictional force, thereby fixes two baffles, and the staff opens the valve of oxygen case simultaneously, makes the inside oxygen of oxygen case get into the inside of experiment box through going out the oxygen pipe, and then prevents that the inside mice of experiment box from discovering the oxygen deficiency phenomenon.
2. In the invention, the motor box, the motor rotating shaft, the cleaning plate, the cleaning brush and the illuminating lamp are arranged in a matching way, so that the motor box is fixedly connected with the experimental box body when the device is used, thereby preventing the idling of the motor, the worker starts the motor to drive the motor rotating shaft to rotate, when the motor rotating shaft rotates, the cleaning plate is fixedly connected with the rotating shaft of the motor, so as to drive the cleaning plate to rotate, the cleaning brush is contacted with the inner wall of the experimental box body at the moment, and the excrement generated by the white mouse is scraped and brushed by the cleaning brush, thereby saving the time for workers to manually clean the excrement, simultaneously improving the cleaning efficiency, starting the illuminating lamp by the workers, the illuminating lamp emits light, and therefore workers can observe the experiment condition inside the experiment box body conveniently and timely.
3. According to the invention, through the matching arrangement among the supporting plate, the slot and the inserting rod, when the device is used and an experiment box body needs to be fixed, a worker places the experiment box body on the top of the supporting plate, and the slot and the inserting rod which are mutually matched are respectively arranged inside the supporting plate and at the bottom of the experiment box body, so that the worker can insert the inserting rod into the slot, and further limit and restrict the experiment box body in the supporting plate, and the experiment box body can be fixed, and the experiment box body is prevented from shaking.
Drawings
FIG. 1 is a schematic structural view of the present invention;
FIG. 2 is a schematic view of the internal structure of the experimental box of the present invention;
FIG. 3 is a schematic view of the internal structure of the motor case of the present invention;
FIG. 4 is a schematic view of the chute structure of the present invention;
FIG. 5 is a schematic view of the structure of the illumination lamp of the present invention;
fig. 6 is a schematic view of an explosion structure of the experimental box and the supporting plate.
In the figure: 1. an experiment box body; 2. a chute; 3. a slider; 4. a partition plate; 5. air holes are formed; 6. a screw; 7. a box cover; 8. A slideway; 9. locking the nut; 10. connecting blocks; 11. placing a rack; 12. an oxygen tank; 13. an oxygen outlet pipe; 14. a motor case; 15. a motor; 16. a motor shaft; 17. cleaning the plate; 18. cleaning the brush; 19. an illumination lamp socket; 20. an illuminating lamp; 21. a reinforcing plate; 22. observing glass; 23. a support plate; 24. a slot; 25. and (4) inserting the rod.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Referring to fig. 1 to 6, in the embodiment of the present invention, a multifunctional experimental box for radiobiology includes an experimental box body 1, sliding grooves 2 are formed on both sides of an inner portion of the experimental box body 1, sliding blocks 3 are slidably connected to an inner portion of the sliding grooves 2, the sliding blocks 3 extend to an outer portion of the sliding grooves 2, partition plates 4 are fixedly connected to tops of the sliding blocks 3, air holes 5 are formed in the partitions 4, screw rods 6 are fixedly connected to both sides of tops of the partition plates 4, a box cover 7 is fixedly connected to a top portion of the experimental box body 1, sliding ways 8 are formed on both sides of an inner portion of the box cover 7, the screw rods 6 extend to an outer portion of the sliding ways 8, locking nuts 9 are fixedly connected to outer surfaces of the screw rods 6, a connecting block 10 is fixedly connected to one side of an outer surface of the experimental box body 1, a placing frame 11 is fixedly connected to one side of the connecting block 10, an oxygen box 12 is movably installed in the placing frame 11, and oxygen is provided in the oxygen box 12, an oxygen outlet pipe 13 is fixedly connected inside the oxygen box 12, and the oxygen outlet pipe 13 penetrates into the experiment box body 1; when the worker needs to reduce the moving range of the mouse in the experiment box body 1, the worker holds the top of the screw rod 6, so as to move the screw rod 6 to the center of the experiment box body 1, the partition plates 4 are fixedly connected with the screw rod 6, so that when the screw rod 6 moves, the partition plates 4 can move in the sliding groove 2 through the sliding blocks 3, so that under the thrust of the worker, the two partition plates 4 can move along the center of the experiment box body 1, so as to isolate the experiment box body 1 into three parts, at the moment, the mouse can only move in the middle of the experiment box body 1, so as to shorten the moving area of the mouse, the mouse is simple and convenient, after the moving area of the mouse is shortened, the worker twists the locking nut 9, so that the locking nut 9 moves downwards on the outer surface of the screw rod 6, so as to contact with the top of the box cover 7, make lock nut 9 and case lid 7 produce frictional force to fix two baffles 4, the staff opens the valve of oxygen case 12 simultaneously, makes the inside oxygen of oxygen case 12 get into the inside of experiment box 1 through going out oxygen pipe 13, and then prevents that the inside mice of experiment box 1 from discovering the oxygen deficiency phenomenon.
The number of the partition plates 4 is two, the number of the air holes 5 is several, the air holes 5 are divided into two groups, each group of air holes 5 is arranged in the partition plates 4 in a rectangular array mode, and oxygen in the experiment box body 1 can enter the middle of the experiment box body 1 through the air holes 5 by means of arrangement of the air holes 5, so that the phenomenon of oxygen deficiency of mice is prevented; the two sides of the outer surface of the experiment box body 1 are fixedly connected with motor boxes 14, a motor 15 is arranged inside the motor boxes 14, the output end of the motor 15 is rotatably connected with a motor rotating shaft 16, one end of the motor rotating shaft 16 extends into the experiment box body 1, and the motor boxes 14 are fixedly connected with the experiment box body 1, so that the motor 15 is prevented from idling, and a worker starts the motor 15 to enable the motor 15 to drive the motor rotating shaft 16 to rotate; motor shaft 16's one end fixedly connected with cleaning plate 17, one side fixedly connected with cleaning brush 18 of cleaning plate 17, and cleaning brush 18's quantity is two, when motor shaft 16 is rotating, because cleaning plate 17 and motor shaft 16 fixed connection, thereby drive cleaning plate 17 and rotate, cleaning brush 18 will produce the contact with the inner wall of experiment box 1 this moment, thereby scrape the brush through cleaning brush 18 the excrement that the mice produced, and then save the time of the manual clearance excrement of staff, the efficiency of clearance has also been improved simultaneously.
An illuminating lamp holder 19 is fixedly connected to the inner top wall of the box cover 7, an illuminating lamp 20 is arranged inside the illuminating lamp holder 19, and a worker starts the illuminating lamp 20 to enable the illuminating lamp 20 to emit light, so that the worker can observe the experiment condition inside the experiment box body 1 in time; the front side of the experiment box body 1 is fixedly connected with a reinforcing plate 21, a cavity is formed in the reinforcing plate 21, observation glass 22 is fixedly connected in the cavity, the number of the observation glass 22 is six, a baffle is hinged to the other side of the experiment box body 1, the observation glass 22 is transparent, so that the eyes of workers can see the inside of the experiment box body 1 clearly, and the baffle is hinged to the experiment box body 1, so that the workers open the baffle and throw mice into the inside of the experiment box body 1; the bottom of the experiment box body 1 is provided with a supporting plate 23, a slot 24 is formed in the supporting plate 23, inserting rods 25 are fixedly connected to two sides of the bottom of the experiment box body 1, the inserting rods 25 are inserted in the slot 24, when the experiment box body 1 needs to be fixed, a worker places the experiment box body 1 on the top of the supporting plate 23, and the slot 24 and the inserting rod 25 which are mutually matched are respectively arranged in the supporting plate 23 and the bottom of the experiment box body 1, so that the worker can insert the inserting rods 25 into the slot 24, and further limit and restrict the experiment box body 1 in the supporting plate 23, so that the experiment box body 1 can be fixed, and the experiment box body 1 is prevented from shaking; the quantity of slot 24 is eight, and every four of eight slots 24 are a set of, and the size between every two liang of slots 24 of every group, distance homoenergetic equal, through eight slots 24's setting, can make backup pad 23 can fix two experiment boxes 1.
The working principle of the invention is as follows: when the worker needs to reduce the moving range of the mouse in the experiment box body 1, the worker holds the top of the screw rod 6, so as to move the screw rod 6 to the center of the experiment box body 1, the partition plates 4 are fixedly connected with the screw rod 6, so that when the screw rod 6 moves, the partition plates 4 can move in the sliding groove 2 through the sliding blocks 3, so that under the thrust of the worker, the two partition plates 4 can move along the center of the experiment box body 1, so as to isolate the experiment box body 1 into three parts, at the moment, the mouse can only move in the middle of the experiment box body 1, so as to shorten the moving area of the mouse, the mouse is simple and convenient, after the moving area of the mouse is shortened, the worker twists the locking nut 9, so that the locking nut 9 moves downwards on the outer surface of the screw rod 6, so as to contact with the top of the box cover 7, so that the lock nut 9 and the box cover 7 generate friction force to fix the two partition plates 4, meanwhile, a worker opens a valve of the oxygen box 12 to enable oxygen inside the oxygen box 12 to enter the interior of the experiment box 1 through the oxygen outlet pipe 13, thereby preventing the mice inside the experiment box 1 from discovering an oxygen deficiency phenomenon, the motor box 14 is fixedly connected with the experiment box 1 to prevent the motor 15 from idling, the worker starts the motor 15 to enable the motor 15 to drive the motor rotating shaft 16 to rotate, when the motor rotating shaft 16 rotates, the cleaning plate 17 is fixedly connected with the motor rotating shaft 16 to drive the cleaning plate 17 to rotate, at the moment, the cleaning brush 18 contacts with the inner wall of the experiment box 1, thereby scraping excrement generated by the mice through the cleaning brush 18, and further saving the time for the worker to manually clean the excrement, meanwhile, the cleaning efficiency is improved, and the worker starts the illuminating lamp 20, so that the illuminating lamp 20 emits light, and the worker can observe the experiment condition inside the experiment box body 1 in time.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and the technical solutions and the inventive concepts thereof according to the present invention should be equivalent or changed within the scope of the present invention.