CN211485243U - Wound surface composite dressing containing bioactive glass - Google Patents

Wound surface composite dressing containing bioactive glass Download PDF

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Publication number
CN211485243U
CN211485243U CN201922184318.0U CN201922184318U CN211485243U CN 211485243 U CN211485243 U CN 211485243U CN 201922184318 U CN201922184318 U CN 201922184318U CN 211485243 U CN211485243 U CN 211485243U
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China
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layer
bioactive glass
wound surface
wound
composite dressing
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张建鑫
曹晶晶
周新钦
张明
石锐
杨帅
王川
郑豪
李果
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Henan Huibo Medical Co ltd
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Henan Huibo Medical Co ltd
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Abstract

The utility model discloses a wound surface composite dressing containing bioactive glass to be close to wound surface one side and be the inlayer, from interior to exterior include antibiotic promoting to heal that the layer is laminated, deodorant absorbed layer, far infrared ceramic fibre layer, porous silica gel layer and back sheet in proper order, antibiotic promoting to heal that the layer is the composite fiber rete of adhering to bioactive glass and enzyme disinfectant, the deodorant absorbed layer is activated carbon fiber layer. The utility model discloses a composite fiber rete that the layer is formed for electrostatic spinning is closed to antibiotic promotion, can regard as the good carrier of taking medicine on the one hand, load bioactive glass and enzyme disinfectant on this fibre rete, and the local pH that causes when having avoided bioactive glass and body fluid to exchange is too high. On the other hand, the wound surface exudate can be siphoned, the wound surface exudate and the rotten meat digested by the enzyme disinfectant are rapidly led out under the siphoning effect and enter the deodorization absorption layer, the absorption efficiency is improved, the wound surface is prevented from being infiltrated by the exudate, and a favorable healing environment is provided.

Description

Wound surface composite dressing containing bioactive glass
Technical Field
The utility model relates to a composite dressing, in particular to a wound surface composite dressing containing bioactive glass.
Background
At present, the skin is broken or damaged under the action of external force to form a wound surface. Skin wounds are always a clinical problem threatening human health, the number of patients suffering from acute and chronic skin wounds in the world is up to 4000 ten thousand, particularly skin wound repair difficulties caused by malnutrition, tissue perfusion failure and ischemia-reperfusion injury, bacterial infection and necrotic tissue persistence, diabetes, cell aging, traumatic full-thickness skin defect (skin avulsion), deep burns, skin tumor ulceration and the like are caused, and besides influencing the barrier function and appearance of the skin, the skin wound repair difficulties are more likely to cause systemic metabolic disorder, infection and even death. It is known that the slow healing of the wound may be caused by the decrease of the function of fibroblasts, the lack of growth factors at the wound, the change of extracellular mechanisms, and the microcirculation disturbance at the affected part. The completeness of damaged tissue repair depends on the regeneration capacity of damaged tissues and cells, and is simultaneously regulated and controlled by a plurality of cytokines and other factors such as chalones, extracellular matrix and the like, wherein the reduction of the local growth factors and the number and the activity of receptors of the wound surface is an important reason for the difficult healing of the wound surface. The bioactive glass is a material which can repair, replace and regenerate body tissues and can enable the tissues and the materials to form bonding action. Bioactive glass materials are not ideal for their anti-bacterial and anti-inflammatory effects simply by contacting body fluids to cause an increase in pH upon exchange of the sample, and higher pH can result in greater skin irritation. The direct coating of the bioactive glass powder can cause skin pricking feeling caused by instantaneous over-high pH, and the hemostatic and seepage-absorbing effects of gel and paste preparations are poor. Therefore, the wound repair composite dressing which has bioactivity, can stimulate the synthesis of endogenous growth factors and has certain mechanical strength is prepared, and the wound repair composite dressing has great research and application values.
SUMMERY OF THE UTILITY MODEL
In order to overcome the defects of the prior art, the utility model aims to provide a wound surface composite dressing containing bioactive glass, which has the characteristics of good healing promoting effect and convenient use.
The purpose of the utility model is realized by adopting the following technical scheme:
the wound surface composite dressing containing bioactive glass takes one side close to a wound surface as an inner layer, and sequentially comprises an antibacterial healing promoting layer, a deodorizing absorption layer, a far infrared ceramic fiber layer, a porous silica gel layer and a back lining layer from inside to outside, wherein the antibacterial healing promoting layer is a composite fiber film layer attached with bioactive glass and an enzyme disinfectant, and the deodorizing absorption layer is an activated carbon fiber layer.
Furthermore, the porosity of the composite fiber film layer is more than 90%, and the thickness of the composite fiber film layer is 0.1-0.5 mm.
Furthermore, the thickness of the activated carbon fiber layer is 0.5-1 cm.
Further, the thickness of the far infrared ceramic fiber layer is 0.1-0.5 mm.
Furthermore, the punching rate of the porous silica gel layer is 50-90%, the diameter of the hole is 0.5-2mm, and the thickness is 0.1-0.5 mm.
Further, the sizes of the antibacterial healing promoting layer, the deodorization absorption layer and the far infrared ceramic layer are equal and smaller than the sizes of the porous silica gel layer and the backing layer, and the sizes of the porous silica gel layer and the backing layer are equal.
Further, the backing layer is a polyurethane film.
Furthermore, an isolation layer is arranged on the composite fiber film layer.
Further, the isolation layer is release paper.
Compared with the prior art, the beneficial effects of the utility model reside in that: the utility model provides a wound surface composite dressing containing bioactive glass, wherein antibiotic healing promotion layer has micrometer membrane structure and very high specific surface area for the composite fiber rete that electrostatic spinning formed, can regard as the good carrier of taking medicine on the one hand, and load bioactive glass and enzyme disinfectant on this fiber rete have avoided the local pH that bioactive glass and body fluid caused when exchanging too high. On the other hand, the wound surface exudate can be siphoned, the wound surface exudate and the rotten meat digested by the enzyme disinfectant are rapidly led out under the siphoning effect and enter the deodorization absorption layer, the absorption efficiency is effectively improved, the wound surface is prevented from being infiltrated by a large amount of exudate, and a favorable healing environment is ensured. The self-heating function of the far infrared ceramic fiber layer can achieve the effect of auxiliary treatment on inflammation and pain of wounds, avoid the phenomenon that the temperature is too high and secondary damage is caused due to direct contact with fragile skin of the wounds, and meanwhile, can prevent exudates such as bloodstain on the wound surface from being rapidly solidified to block an absorption channel, so that the effect of assisting in fully absorbing the exudates is achieved. In addition, the self-heating function of the far infrared ceramic fiber layer can increase the viscosity of the porous silica gel layer, the reduction of the viscosity of the dressing paste is avoided when the seepage is more, and the polyurethane film layer provides a barrier for the whole wound surface covered by the dressing, such as wet healing and external pollution blocking. The antibacterial healing promoting layer, the deodorization absorption layer and the far infrared ceramic fiber layer have synergistic effect to form a system for resisting bacteria, diminishing inflammation and absorbing seepage, thereby promoting the healing of the wound surface.
Drawings
Fig. 1 is a schematic structural diagram of the wound composite dressing containing bioactive glass of the present invention;
in the figure: 1. an antibacterial healing promoting layer; 2. a deodorizing absorbent layer; 3. a far infrared ceramic fiber layer; 4. a porous silica gel layer; 5. a backing layer; 6. an isolation layer.
Detailed Description
The present invention will be further described with reference to the accompanying drawings and the detailed description, and it should be noted that the embodiments or technical features described below can be arbitrarily combined to form a new embodiment without conflict.
As shown in fig. 1: a wound composite dressing containing bioactive glass takes one side close to a wound as an inner layer, and sequentially comprises an antibacterial healing promoting layer 1, a deodorization absorption layer 2, a far infrared ceramic fiber layer 3, a porous silica gel layer 4 and a backing layer 5 from inside to outside, wherein the antibacterial healing promoting layer 1 is a composite fiber film layer attached with bioactive glass and an enzyme disinfectant. The composite fiber membrane layer has high affinity with a human body, has certain mechanical strength and very high specific surface area, can be used as a good medicine taking carrier, has high porosity, has the porosity of more than 90 percent and the thickness of 0.1-0.5mm, builds a certain carrier for the attachment of bioactive glass and enzyme disinfector, and avoids the overhigh local pH caused by the exchange of the bioactive glass and body fluid. On the other hand, the wound surface exudate can be siphoned, the wound surface exudate and the rotten meat digested by the enzyme disinfectant are rapidly led out under the siphoning effect and enter the deodorization absorption layer 2, the absorption efficiency is effectively improved, a large amount of exudate is prevented from infiltrating the wound surface, and a favorable healing environment is ensured. The composite fiber film layer has good permeability, thereby being beneficial to the respiration of cells in a wound area.
The deodorization absorption layer 2 is an activated carbon fiber layer, and preferably, the thickness of the activated carbon fiber layer is 0.5-1 cm. The active carbon fiber layer can absorb a large amount of exudate relatively, has a certain function of filtering and deodorizing, avoids the peculiar smell brought by the wound exudate, and relieves the psychological damage to patients and the inconvenience of medical workers.
Preferably, the thickness of the far infrared ceramic fiber layer 3 is 0.1 to 0.5 mm. The self-heating function of the far infrared ceramic fiber can achieve the effect of adjuvant therapy on inflammation and pain of wounds, and meanwhile, secondary damage caused by overhigh temperature due to direct contact with fragile skin of the wounds is avoided. Meanwhile, the rapid solidification of exudates such as bloodstain and the like on the wound surface can be avoided, so that an absorption channel is blocked, and the effect of assisting in fully absorbing the exudates is achieved. In addition, the self-heating function of the far infrared ceramic fiber layer 3 can increase the viscosity of the porous silica gel layer 4, and the reduction of the viscosity of the dressing paste is avoided when the seepage is more. Porous silica gel layer 4 plays the adhesive effect in compound dressing, because the special viscidity of silica gel, has better gomphosis effect with human skin fold, and it is inseparabler to paste the clothes, and it is less to peel off painful sense, and is ventilative good, still has the effect of pasting repeatedly in addition, provides the chance of secondary operation for patient or medical staff. Preferably, the perforated rate of the porous silica gel layer 4 is 50-90%, the diameter of the pores is 0.5-2mm, and the thickness is 0.1-0.5 mm.
The sizes of the antibacterial healing promoting layer 1, the deodorization absorption layer 2 and the far infrared ceramic layer are equal and are all smaller than the sizes of the porous silica gel layer 4 and the backing layer 5, and the sizes of the porous silica gel layer 4 and the backing layer 5 are equal. The backing layer 5 is a polyurethane film. The composite fiber film layer is provided with an isolating layer 6 to prevent external pollution. Preferably, the isolation layer 6 is release paper.
The above embodiments are only preferred embodiments of the present invention, and the protection scope of the present invention cannot be limited thereby, and any insubstantial changes and substitutions made by those skilled in the art based on the present invention are all within the protection scope of the present invention.

Claims (9)

1. The wound surface composite dressing containing bioactive glass is characterized in that one side close to a wound surface is taken as an inner layer, and the wound surface composite dressing sequentially comprises an antibacterial healing promoting layer, a deodorizing absorption layer, a far infrared ceramic fiber layer, a porous silica gel layer and a back lining layer from inside to outside, wherein the antibacterial healing promoting layer is a composite fiber film layer attached with the bioactive glass and an enzyme disinfectant, and the deodorizing absorption layer is an activated carbon fiber layer.
2. A wound composite dressing containing bioactive glass as claimed in claim 1, wherein the porosity of the composite fibre membrane layer is greater than 90% and the thickness is 0.1-0.5 mm.
3. A wound composite dressing containing bioactive glass as claimed in claim 1, wherein the thickness of the activated carbon fibre layer is 0.5-1 cm.
4. A wound composite dressing containing bioactive glass as claimed in claim 1, wherein the thickness of the far infrared ceramic fibre layer is 0.1-0.5 mm.
5. A wound composite dressing containing bioactive glass as claimed in claim 1, wherein the porous silica gel layer has a perforation rate of 50-90%, a pore diameter of 0.5-2mm and a thickness of 0.1-0.5 mm.
6. A wound composite dressing containing bioactive glass as claimed in claim 1, wherein the antibacterial healing promoting layer, the deodorant absorbing layer and the far infrared ceramic layer are equal in size and smaller than the porous silica gel layer and the backing layer, and the porous silica gel layer and the backing layer are equal in size.
7. A wound composite dressing comprising bioactive glass as claimed in claim 1, wherein the backing layer is a polyurethane film.
8. A wound composite dressing containing bioactive glass as claimed in claim 1, wherein an isolating layer is provided on the composite fibre membrane layer.
9. A wound composite dressing containing bioactive glass as claimed in claim 8, wherein the barrier layer is release paper.
CN201922184318.0U 2019-12-09 2019-12-09 Wound surface composite dressing containing bioactive glass Active CN211485243U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201922184318.0U CN211485243U (en) 2019-12-09 2019-12-09 Wound surface composite dressing containing bioactive glass

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Application Number Priority Date Filing Date Title
CN201922184318.0U CN211485243U (en) 2019-12-09 2019-12-09 Wound surface composite dressing containing bioactive glass

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CN211485243U true CN211485243U (en) 2020-09-15

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112843322A (en) * 2021-01-11 2021-05-28 苏州汇涵医用科技发展有限公司 Preparation method of black bioactive ceramic dressing
CN113318260A (en) * 2021-06-28 2021-08-31 华东理工大学 Medical antibacterial dressing and preparation method thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112843322A (en) * 2021-01-11 2021-05-28 苏州汇涵医用科技发展有限公司 Preparation method of black bioactive ceramic dressing
CN113318260A (en) * 2021-06-28 2021-08-31 华东理工大学 Medical antibacterial dressing and preparation method thereof

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