CN211374641U - PH electrode flow-through cell and back pressure valve combined device - Google Patents
PH electrode flow-through cell and back pressure valve combined device Download PDFInfo
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- CN211374641U CN211374641U CN201922264114.8U CN201922264114U CN211374641U CN 211374641 U CN211374641 U CN 211374641U CN 201922264114 U CN201922264114 U CN 201922264114U CN 211374641 U CN211374641 U CN 211374641U
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Abstract
The utility model discloses a pH electrode flow-through cell and back pressure valve combined device, it includes the post selection valve, its stator has a plurality of holes that are located and use the axis of rotation of rotor as the center equiangular and equidistance ground distribution, be located the centre bore on the axis of rotation of rotor, the centre bore is sample feed liquor hole, two holes are liquid outlet holes, six holes are the entry of protection/buffer solution, seven holes are the waste liquid discharge port, the rotor has the first groove that can link together one in a plurality of holes and centre bore, can be with the three groove that two adjacent in a plurality of holes are linked together; one end of the pH electrode flow cell is connected with one hole, and the other end of the pH electrode flow cell is connected with five holes; and one end of the back pressure valve is connected with the three holes, and the other end of the back pressure valve is connected with the four holes. Due to the adoption of the technical scheme, four states of independent work of the pH electrode flow cell, independent work of the back pressure valve, simultaneous work of the pH electrode flow cell and the back pressure valve and simultaneous non-work of the pH electrode flow cell and options of waste liquid discharge are realized, the operation is clear and convenient, and mistakes are not easy to occur.
Description
Technical Field
The utility model relates to a pH electrode flow-through cell and back pressure valve combined device for liquid chromatogram, fluid transmission and control.
Background
The detection of pH in mobile phase using pH electrodes is an important step in liquid chromatography, and its role includes several aspects including but not limited to: a. determining the polarity of the separated components; b. columns are generally used in a pH range, and the mobile phase having too high or too low a pH value may damage the silica gel surface of the column, resulting in damage to the column. The detection of the pH electrode is very dependent on a very thin hydrated gel layer on the surface of a glass film of a bulb at the end part of the pH electrode, and the pH electrode is characterized in that: a. the good reaction with H + ions in the solution can be realized only under the condition of sufficient wetting; when the pH electrode is in a non-working state, the bulb needs to be soaked in a protective solution, so that the asymmetric potential is greatly reduced and tends to be stable to accelerate the response of the electrode and improve the accuracy, wherein the common pH electrode protective solution is a 3mol/L saturated KCL solution; before the ph electrode is used, in order to make the measured value accurate and precise, the most common practice is to calibrate and position the electrode using a standard buffer solution, which is more specific and depends on the detection target of the electrode.
However, in the existing chromatographic apparatus, the use of pH electrodes faces the following problems: the pH electrode flow cell is usually used as a component of a chromatographic separation main flow path, all reagents passing through the flow path pass through the pH electrode flow cell in the whole separation process, a certain part of the reagents do not need to be separately detected in pH value, and even some reagents can cause negative influence on an electrode bulb; because the processes are continuously carried out, the action of immersing the electrode bulbs in the protective liquid and the action of correcting and positioning the electrodes by using the standard buffer solution cannot be realized in a working state, and in order to ensure the efficacy of the electrodes, the electrodes have to be replaced manually and are immersed or corrected outside;
in addition, the back pressure valve is also called a check valve, is mainly used for a pipeline system, compresses an internal spring by the force generated by the flowing of a medium in the pipeline, realizes the automatic opening and closing functions, and mainly functions to set the forward flow path pressure required by opening and prevent the medium from flowing backwards. However, in the existing chromatographic apparatus, similar to the pH electrode flow cell, there are some situations where a back pressure valve is not necessary or cannot be used, for example, where the pressure of the forward flow path is not enough but the open circuit needs to be ensured. The pH electrode flow cell and the backpressure valve are combined, four states of simultaneous working of the pH electrode flow cell and the backpressure valve, independent working of the pH electrode, independent working of the backpressure valve and simultaneous non-working of the pH electrode flow cell and the backpressure valve exist, the four states can be realized only by a plurality of switching valves, and the process and the control are complex and tedious.
Disclosure of Invention
In order to solve the above problems, an object of the present invention is to provide a pH electrode flow cell and back pressure valve combination device.
In order to achieve the above purpose, the utility model discloses a technical scheme is: a pH electrode flow cell and back pressure valve combined device comprises
The column selection valve comprises a stator and a rotor which are mutually and rotatably connected, wherein the stator is provided with a plurality of holes which are positioned on the rotating axis of the rotor, are equiangularly and equidistantly distributed, and a central hole which is positioned on the rotating axis of the rotor, the central hole is a sample liquid inlet hole, the plurality of holes comprise a hole, a second hole, a third hole, a fourth hole, a fifth hole, a sixth hole and a seventh hole which are sequentially distributed, the second hole is a liquid outlet hole, the sixth hole is an inlet of a protection/buffer solution, the seventh hole is a waste liquid discharge hole, and the rotor is provided with a first groove which can communicate one of the plurality of holes with the central hole, a second groove which can communicate two adjacent holes of the plurality of holes with each other, a third groove;
one end of the pH electrode flow cell is connected with one hole, and the other end of the pH electrode flow cell is connected with five holes;
a back pressure valve having one end connected to the three holes and the other end connected to the four holes;
the coupling device has at least five working states through the rotation of a rotor of the column selection valve, when the coupling device is in a first working state, a central hole is communicated with a second hole through a first groove, a three hole is communicated with a fourth hole through a second groove, a five hole is communicated with a sixth hole through a third groove, and a seven hole is communicated with a first hole through a fourth groove; when the combined device is in a second working state, the central hole is communicated with the first hole through the first groove, the second hole is communicated with the third hole through the second groove, the fourth hole is communicated with the fifth hole through the third groove, and the sixth hole is communicated with the seventh hole through the fourth groove; when the coupling device is in a third working state, the central hole is communicated with the seven holes through the first groove, the first hole is communicated with the second hole through the second groove, the three holes are communicated with the four holes through the third groove, and the five holes are communicated with the six holes through the fourth groove; when the combined device is in a fourth working state, the central hole is communicated with the five holes through the first groove, the six holes are communicated with the seven holes through the second groove, the first hole is communicated with the second hole through the third groove, and the three holes are communicated with the four holes through the fourth groove; when the coupling device is in a fifth working state, the central hole is communicated with the four holes through the first groove, the five holes are communicated with the six holes through the second groove, the seven holes are communicated with the first hole through the third groove, and the two holes are communicated with the three holes through the fourth groove.
Further, the rotor of the column selector valve is controlled to rotate by a software program.
Further, the first groove, the second groove, the third groove and the fourth groove are linear.
Further, the length of the first slot is equal to the distance from the central hole to one hole.
Further, the lengths of the second groove, the third groove and the fourth groove are equal to the distance between two adjacent holes.
Furthermore, the second groove and the fourth groove are symmetrically arranged on two sides of the first groove, and the third groove is perpendicular to the extension line of the first groove.
By adopting the technical scheme, the pH electrode flow cell and back pressure valve combined device is provided with two inlets which are respectively used as a sample liquid inlet and a protection/buffer liquid inlet; a pH electrode flow cell and a back pressure valve are connected; the four states of simultaneous working of a pH electrode flow cell and a back pressure valve, independent working of the pH electrode flow cell, independent working of the back pressure valve and simultaneous non-working of the pH electrode flow cell and the back pressure valve (direct pipeline) and options of waste liquid discharge are realized through the regulation and control of a rotor of a column selection valve; in addition, when the pH electrode flow cell does not work, no matter whether the backpressure valve is in a working state or not, the steps of injecting protective solution to soak the electrode bulbs or injecting standard buffer solution to correct the positioning electrodes can be realized, and the steps are independent from the main pipeline system; the connection rule of the pH electrode flow cell, the back pressure valve and the column selection valve is simple and fixed, the operation is clear and convenient, and errors are not easy to occur.
Drawings
Fig. 1 is a schematic structural diagram of a combined device of a pH electrode flow cell and a back pressure valve in an embodiment of the present invention, which is in a first working state;
FIG. 2 is a schematic structural diagram of the pH electrode flow cell and back pressure valve combination device shown in FIG. 1 in a second working state;
FIG. 3 is a schematic structural diagram of the pH electrode flow cell and back pressure valve combination device shown in FIG. 1 in a third operating state;
FIG. 4 is a schematic structural diagram of the pH electrode flow cell and back pressure valve combination shown in FIG. 1 in a fourth operating state;
FIG. 5 is a schematic structural diagram of the pH electrode flow cell and back pressure valve combination device shown in FIG. 1 in a fifth operating state;
FIG. 6 is a schematic diagram of the front side structure of the stator of the column selection valve in the combined device of the pH electrode flow cell and the back pressure valve shown in FIG. 1;
FIG. 7 is a schematic view of the reverse construction of the stator shown in FIG. 6;
FIG. 8 is a schematic view showing a structure of a rotor of a column selection valve in the apparatus for combining the pH electrode flow cell and the back pressure valve shown in FIG. 1.
The reference numbers in the figures are:
10. a sample injection valve; 11. a stator; 110. a central bore; 111. a hole; 112. two holes; 113. three holes; 114. four holes; 115. five holes are formed; 116. six holes; 117. seven holes; 12. a rotor; 121. a first groove; 122. a second groove; 123. a third groove; 124. a fourth groove;
20. a pH electrode flow cell;
30. a back pressure valve.
Detailed Description
The following detailed description of the preferred embodiments of the present invention, taken in conjunction with the accompanying drawings, enables those skilled in the art to more readily understand the advantages and features of the present invention.
As can be seen from the schematic structural diagrams of fig. 1 to 8, the combined PH electrode flow cell and back pressure valve device in this embodiment includes a column selection valve 10, a PH electrode flow cell 20, and a back pressure valve 30.
The column select valve 10 includes a stator 11 and a rotor 12 rotatably connected to each other. In this embodiment, the rotor 12 of the column selector valve 10 is controlled to rotate by a software program.
The stator 11 has a plurality of holes that are equiangularly and equidistantly distributed about the rotational axis of the rotor 12, and a center hole 110 that is located on the rotational axis of the rotor 12. The central hole 110 is a sample inlet hole and is connected to a sample feeding module. The plurality of holes comprise a hole 111, a hole 112, a hole 113, a hole 114, a hole 115, a hole 116 and a hole 117 which are distributed in sequence. One hole 111 and five holes 115 are used for connecting the pH electrode flow cell 20; three holes 113 and four holes 114 for connecting the back pressure valve 30; the two holes 112 are liquid outlet holes and are usually connected with a collection module; six wells 116 are inlets for protection/buffer; the seven holes 117 are waste liquid discharge ports.
The rotor 12 has a first groove 121 capable of communicating one of the plurality of holes with the center hole 110, a second groove 122 capable of communicating adjacent two of the plurality of holes, a third groove 123, and a fourth groove 124. In this embodiment, the first slot 121, the second slot 122, the third slot 123 and the fourth slot 124 are all linear, the length of the first slot 121 is equal to the distance from the central hole 110 to one hole, and the lengths of the second slot 122, the third slot 123 and the fourth slot 124 are equal to the distance between two adjacent holes. The second groove 122 and the fourth groove 124 are symmetrically disposed at both sides of the first groove 121, and the third groove 123 is perpendicular to an extension line of the first groove 121.
One end of the pH electrode flow cell 20 is connected to one well 111 and the other end is connected to five wells 115.
One end of the back pressure valve 30 is connected to the three holes 113, and the other end is connected to the four holes 114.
The coupling device has at least five operating states by rotation of the rotor 12 of the column selector valve 10.
As shown in fig. 1, the coupling device is in a first working state, the position of the rotor 12 is set to be 0 degree at this time, and at this time, the central hole 110 and the two holes 112 are communicated through the first groove 121, so that a sample enters from the central hole 110 serving as a liquid inlet hole and flows out from the two holes 112 serving as liquid outlet holes, and a direct connection function is realized; at this time, the three hole 113 and the four hole 114 are communicated through the second groove 122, the five hole 115 and the six hole 116 are communicated through the third groove 123, the seven hole 117 and the one hole 111 are communicated through the fourth groove 124, and both the pH electrode flow cell 20 and the back pressure valve 30 are in the non-operating state.
As shown in fig. 2, when the rotor 12 rotates 51.4 degrees counterclockwise, the combination device is in the second working state, in which the central hole 110 and the first hole 111 are communicated with each other through the first groove 121, the second hole 112 and the third hole 113 are communicated with each other through the second groove 122, the fourth hole 114 and the fifth hole 115 are communicated with each other through the third groove 123, and the sixth hole 116 and the seventh hole 117 are communicated with each other through the fourth groove 124, so that the sample enters from the central hole 110, enters the pH electrode flow cell 20 through the first hole 111, enters the back pressure valve 30 through the fifth hole 115 and the fourth hole 114, passes through the third hole 113, and finally flows out from the second hole 112, in which both the pH electrode flow cell 20 and the back pressure valve 30 are in the working state.
As shown in fig. 3, the rotor 12 rotates 102.9 degrees counterclockwise, and the combination is in the third operating state. At this time, the central hole 110 and the seven holes 117 communicate with each other through the first groove 121, and the sample reagent enters from the central hole 110 and flows out from the seven holes 117 as a waste liquid discharge port, thereby performing a waste liquid discharge function. The first hole 111 and the second hole 112 are communicated through the second groove 122, the third hole 113 and the fourth hole 114 are communicated through the third groove 123, the fifth hole 115 and the sixth hole 116 are communicated through the fourth groove 124, and both the pH electrode flow cell 20 and the back pressure valve 30 are in the non-operating state.
As shown in fig. 4, the rotor 12 is rotated 205.7 degrees counterclockwise and the combination is in a fourth operating condition. At this time, the central hole 110 is communicated with the five holes 115 through the first groove 121, the six holes 116 are communicated with the seven holes 117 through the second groove 122, the first hole 111 is communicated with the second hole 112 through the third groove 123, the pH electrode flow cell 20 is in a working state, the sample enters from the central hole 110, enters the pH electrode flow cell 20 through the five holes 115, passes through the first hole 111, and flows out from the second hole 112; at this time, the three-hole 113 and the four-hole 114 communicate with each other through the fourth groove 124, and the back pressure valve 30 is in an inoperative state.
As shown in fig. 5, when the rotor 12 rotates by 257.1 degrees counterclockwise, the combination device is in a fifth working state, the central hole 110 and the four holes 114 communicate with each other through the first groove 121, the two holes 112 and the three holes 113 communicate with each other through the fourth groove 124, the back pressure valve 30 is in a working state, and the sample enters from the central hole 110, enters the back pressure valve 30 through the four holes 114, passes through the three holes 113, and flows out from the two holes 112; at this time, the five holes 115 and the six holes 116 are communicated through the second groove 122, the seven holes 117 and the one hole 111 are communicated through the third groove 123, and the pH electrode flow cell 20 is in an inoperative state.
Particularly, when the combined device is in the first working state and the fifth working state, the protection/buffer solution flows in from the six holes 116 as the inlet of the protection/buffer solution, enters the pH electrode flow cell 20 through the five holes 115, passes through the one hole 111, and flows out from the seven holes 117 as the waste liquid discharge port, the flow pipeline and the main pipeline for sample flow are independent from each other, whether the back pressure valve 30 works or not has no influence on the operation, and the steps of soaking the electrode bulbs with the protection solution or injecting the standard buffer solution to correct the positioning electrode can be realized by manually selecting or switching the solution type by the pre-valve.
The pH electrode flow cell and the back pressure valve combined device in the embodiment are provided with two inlets which are respectively used as a sample liquid inlet and a protection/buffer liquid inlet; a pH electrode flow cell and a back pressure valve are connected; the four states of simultaneous working of a pH electrode flow cell and a back pressure valve, independent working of the pH electrode flow cell, independent working of the back pressure valve and simultaneous non-working of the pH electrode flow cell and the back pressure valve (direct pipeline) and options of waste liquid discharge are realized through the regulation and control of a rotor of a column selection valve; in addition, when the pH electrode flow cell does not work, no matter whether the backpressure valve is in a working state or not, the steps of injecting protective solution to soak the electrode bulbs or injecting standard buffer solution to correct the positioning electrodes can be realized, and the steps are independent from the main pipeline system; the connection rule of the pH electrode flow cell, the back pressure valve and the column selection valve is simple and fixed, the operation is clear and convenient, and errors are not easy to occur.
The above embodiments are only for illustrating the technical concept and features of the present invention, and the purpose of the embodiments is to enable people skilled in the art to understand the contents of the present invention and to implement the present invention, which cannot limit the protection scope of the present invention. All equivalent changes and modifications made according to the spirit of the present invention should be covered by the protection scope of the present invention.
Claims (6)
1. The utility model provides a pH electrode flow-through cell and back pressure valve allies oneself with uses device which characterized in that: it comprises
Column selection valve (10) comprising a stator (11) and a rotor (12) connected in rotation with each other, said stator (11) having a plurality of holes positioned at equal angles and equidistantly distributed around the axis of rotation of said rotor (12), a central hole (110) positioned on the axis of rotation of said rotor (12), said central hole (110) being a sample inlet hole, said plurality of holes comprising a hole (111), a second hole (112), a third hole (113), a fourth hole (114), a fifth hole (115), a sixth hole (116), a seventh hole (117) distributed in sequence, said second hole (112) being a liquid outlet hole, said sixth hole (116) being an inlet for a protection/buffer liquid, said seventh hole (117) being a waste liquid outlet hole, said rotor (12) having a first groove (121) capable of communicating one of said plurality of holes with said central hole (110), a second groove (122) capable of communicating two adjacent of said plurality of holes, A third groove (123) and a fourth groove (124);
a pH electrode flow cell (20) having one end connected to the first well (111) and the other end connected to the five wells (115);
a back pressure valve (30) having one end connected to the three holes (113) and the other end connected to the four holes (114);
said combined device having at least five operating states by rotation of the rotor (12) of the column selection valve (10), when it is in a first operating state, said central hole (110) and said second hole (112) communicating through said first slot (121), said three hole (113) and said four hole (114) communicating through said second slot (122), said five hole (115) and said six hole (116) communicating through said third slot (123), said seven hole (117) and said first hole (111) communicating through said fourth slot (124); when the combined device is in the second working condition, the central hole (110) and the first hole (111) are in communication through the first slot (121), the second hole (112) and the third hole (113) are in communication through the second slot (122), the fourth hole (114) and the fifth hole (115) are in communication through the third slot (123), and the sixth hole (116) and the seventh hole (117) are in communication through the fourth slot (124); when the combined device is in a third working condition, the central hole (110) and the seven holes (117) are in communication through the first slot (121), the first hole (111) and the second hole (112) are in communication through the second slot (122), the three holes (113) and the four holes (114) are in communication through the third slot (123), and the five holes (115) and the six holes (116) are in communication through the fourth slot (124); when the combined device is in a fourth operating condition, the central hole (110) and the five holes (115) communicate through the first slot (121), the six holes (116) and the seven holes (117) communicate through the second slot (122), the first hole (111) and the second hole (112) communicate through the third slot (123), and the three holes (113) and the four holes (114) communicate through the fourth slot (124); when the combined device is in a fifth working condition, the central hole (110) and the four holes (114) are in communication through the first slot (121), the fifth hole (115) and the sixth hole (116) are in communication through the second slot (122), the seventh hole (117) and the first hole (111) are in communication through the third slot (123), and the second hole (112) and the third hole (113) are in communication through the fourth slot (124).
2. The combination pH electrode flow cell and back pressure valve device of claim 1, wherein: the rotor (12) of the column selector valve (10) is controlled in rotation by a software program.
3. The combination pH electrode flow cell and back pressure valve device of claim 1, wherein: the first groove (121), the second groove (122), the third groove (123) and the fourth groove (124) are linear.
4. The combination pH electrode flow cell and back pressure valve device of claim 1, wherein: the length of the first slot (121) is equal to the distance from the central hole (110) to one of the holes.
5. The combination pH electrode flow cell and back pressure valve device of claim 1, wherein: the lengths of the second groove (122), the third groove (123) and the fourth groove (124) are equal to the distance between two adjacent holes.
6. The combination pH electrode flow cell and back pressure valve device of claim 1, wherein: the second groove (122) and the fourth groove (124) are symmetrically arranged on two sides of the first groove (121), and the third groove (123) is perpendicular to the extension line of the first groove (121).
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201922264114.8U CN211374641U (en) | 2019-12-17 | 2019-12-17 | PH electrode flow-through cell and back pressure valve combined device |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201922264114.8U CN211374641U (en) | 2019-12-17 | 2019-12-17 | PH electrode flow-through cell and back pressure valve combined device |
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| CN211374641U true CN211374641U (en) | 2020-08-28 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114235898A (en) * | 2021-12-14 | 2022-03-25 | 苏州英赛斯智能科技有限公司 | Multi-position rotary valve |
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2019
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114235898A (en) * | 2021-12-14 | 2022-03-25 | 苏州英赛斯智能科技有限公司 | Multi-position rotary valve |
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