CN210923732U

CN210923732U - Blood coagulation parameter detects uses test box

Info

Publication number: CN210923732U
Application number: CN201921776277.8U
Authority: CN
Inventors: 陈曙; 胡敏; 张起莹; 胡娇; 孙亚婷
Original assignee: Shiji 1kang Tianjin Medical Technology Development Co ltd
Current assignee: Shiji 1kang Tianjin Medical Technology Development Co ltd
Priority date: 2019-10-22
Filing date: 2019-10-22
Publication date: 2020-07-03
Anticipated expiration: 2029-10-22

Abstract

The utility model relates to a test box for detecting coagulation parameters, which comprises a test box body and a transmission mechanism, wherein the test box body comprises a box body, a sample inlet port, a temperature control part, a test cavity, a hydrophobic filter and a vacuum port which are sequentially communicated on the box body, the temperature control part comprises a serpentine pipeline, a filling material and a heating pipe, support disks are respectively arranged below each test box body, the lower parts of the support disks are simultaneously connected with the transmission mechanism, the arrangement of the serpentine pipeline effectively increases the retention time of a blood sample in the temperature control part, so that the blood sample reaches the optimal temperature for mixing with a reagent before entering the test cavity, the transmission mechanism is started in the placement process, the support disk above the transmission mechanism drives the test box body to move, the fluidity of fluid in the test cavity is improved, the mixing effect of the blood sample and a chemical reagent is effectively improved, the manual shaking is replaced, and the working, ensures that the detection result is reliable and accurate, thereby more accurately evaluating the coagulation parameters of the blood sample from the subject.

Description

Blood coagulation parameter detects uses test box

Technical Field

The utility model relates to a clinical medicine inspection field especially relates to a blood coagulation parameter detects and uses test box.

Background

The blood coagulation function is an important function of blood, a patient suffering from heart diseases needs to be subjected to blood coagulation tests regularly to determine parameters such as blood coagulation time of the patient, the parameters are used as important parameters for evaluating the condition of heavy bleeding in an operation during the operation, after the operation, the patient also needs to take anticoagulants such as heparin or warfarin orally to prevent pulmonary embolism thrombosis or other excessive blood coagulation problems, besides, the blood coagulation time of the patient with hyperlipidemia and hyperglycemia needs to be monitored regularly to prevent thrombosis, and therefore, the detection and evaluation of the blood coagulation function are clinically significant in medicine.

The coagulation process is a series of processes in which coagulation factors are sequentially activated by enzymolysis (known as intrinsic and extrinsic coagulation pathways in academia), and prothrombin is activated into thrombin, which promotes fibrinogen to form a solid thrombus clot. In the process of testing the blood coagulation parameters, different types of reagents are placed in a testing cavity according to the testing requirements, wherein the reagents comprise abciximab, cytochalasin D, kaolin, diatomite, thrombin, adenosine diphosphate and the like, a blood sample of a subject enters the testing cavity to interact with the reagents, and then the blood sample is arranged on a detector to be analyzed and tested, the conventional testing box needs to be shaken up manually after medical personnel collect the blood sample, when the blood samples of a plurality of subjects need to be tested, the workload of the medical personnel is increased in the process, the working efficiency is influenced, in addition, when the blood sample to be tested is more, the blood sample to be tested is placed for a period of time and then is correspondingly tested and tested, the process causes the uneven mixing of the blood sample and the reagents, so that the testing results have errors of different degrees, thereby influencing medical workers to make timely and accurate medical decisions for the subjects.

SUMMERY OF THE UTILITY MODEL

The utility model aims to solve the technical problem that overcome exist among the prior art not enough, provide a blood coagulation parameter testing box for measuring, ensure that blood sample and reagent mix fully, improve blood coagulation parameter measurement accuracy.

The utility model discloses a realize through following technical scheme:

the utility model provides a blood coagulation parameter detects uses test box, its characterized in that, includes the test box body and locates the drive mechanism of test box body below, the test box body is provided with 3, and the test box body includes the box body, communicates in proper order sample inlet port, accuse temperature portion, test chamber, hydrophobic filter and vacuum port on the box body, the position rigid coupling in the relative test chamber in box body surface has a positioning substrate, positioning substrate is equipped with the couplant layer outward, accuse temperature portion includes serpentine pipe, wraps up the stopping outside serpentine pipe and locates the heating pipe in the stopping, serpentine pipe one end is linked together through advancing appearance pipe and sample inlet port, and the serpentine pipe other end is linked together through pipette and test chamber, each test box body below is equipped with the supporting disk respectively, and each supporting disk below is connected with drive mechanism simultaneously.

According to the above technical scheme, preferably, the temperature control portion is communicated with a plurality of test chambers, each of the test chambers is arranged in parallel, and each of the test chambers is communicated with the hydrophobic filter.

According to the above technical scheme, preferably, the transmission mechanism includes a gear ring, a central gear, internal gears, a connecting plate, a rotating shaft and a motor, the central gear is arranged in the gear ring and concentrically arranged with the gear ring, three internal gears are respectively engaged between the central gear and the gear ring, the middle portions of the internal gears are respectively and upwardly and fixedly connected with the middle portions of the supporting plates, the internal gears are respectively connected with each other through the connecting plate, each connecting plate is fixedly connected with the side wall of the rotating shaft, the lower end of the rotating shaft is connected with the motor, and the upper end of the rotating shaft is rotatably connected.

According to the above technical scheme, preferably, one end of the serpentine pipeline close to the pipette is provided with a temperature sensor, the temperature sensor is electrically connected with a heating controller, and the heating controller is electrically connected with the heating pipe.

According to the technical scheme, preferably, the test cavity is wrapped by the heat insulation layer.

According to the above technical solution, preferably, the temperature control portion is isolated in the test box body by a thermal insulation layer.

The utility model has the advantages that:

the setting of serpentine circuit has effectively increased the dwell time of blood sample at accuse temperature portion for blood sample reaches the optimum temperature of mixing with reagent before getting into the test chamber, meanwhile, place the in-process and start drive mechanism, make the supporting disk of its top drive the motion of test box body, improve the mobility of test intracavity fluid, the mixed effect of blood sample and chemical reagent has effectively been improved, it shakes evenly to replace the manual work, when improving work efficiency, ensure that the testing result is reliable, it is accurate, thereby the coagulation parameter that more accurate aassessment comes from examinee's blood sample.

Drawings

Fig. 1 is a schematic view of the structure of the present invention.

Fig. 2 is a schematic bottom view of the transmission mechanism of the present invention.

Fig. 3 is a schematic structural diagram of the body part of the test cartridge of the present invention.

In the figure: 1. a sample inlet port; 2. a vacuum port; 3. a test box body; 4. positioning the substrate; 5. a heat-insulating layer; 6. a test chamber; 7. a temperature control device; 8. a support disc; 9. a card slot; 10. a ring gear; 11. a base; 12. an internal gear; 13. a connecting plate; 14. a motor; 15. a sun gear; 16. a rotating shaft; 17. a hydrophobic filter; 18. a temperature sensor; 19. a heating controller; 20. heating a tube; 21. a serpentine circuit; 22. an insulating layer.

Detailed Description

In order to make those skilled in the art better understand the technical solution of the present invention, the present invention will be further described in detail with reference to the accompanying drawings and preferred embodiments.

As shown in the figure, the utility model comprises a test box body 3 and a transmission mechanism arranged below the test box body 3, wherein the test box body 3 is provided with 3, the test box body 3 comprises a box body, a sample inlet port 1, a temperature control part, a test chamber 6, a hydrophobic filter 17 and a vacuum port 2 which are sequentially communicated on the box body, a positioning substrate 4 is fixedly connected with the position of the surface of the box body relative to the test chamber 6, a couplant layer is arranged outside the positioning substrate 4, the positioning substrate 4 is clamped at the connecting position of a detector in the process that the test box body 3 is arranged on the detector, the positioning substrate 4 can be made of ultrasonic waves, the ultrasonic waves output by a sound wave generator pass through the positioning substrate 4 and the couplant layer, are transmitted and focused into the test chamber 6, are reflected by the end part of the test chamber 6 and then are received by the sound wave generator, and the detection terminal, the temperature control part comprises a serpentine pipeline 21, a filling material wrapped outside the serpentine pipeline 21 and a heating pipe 20 arranged in the filling material, wherein the filling material is made of heat transfer material, the heat of the heating pipe 20 can be transferred to the blood sample in the serpentine pipeline 21, the interaction between the blood sample and the reagent in the testing cavity 6 is accelerated, the blood coagulation parameter detection requirement is met, the utility model discloses a test box, including test box body 3, snakelike pipeline 21, supporting disk 8 upper surface, snakelike pipeline 21 one end is linked together through advance appearance pipe and introduction port 1, and the snakelike pipeline 21 other end is linked together through pipette and test chamber 6, each 3 below of test box body are equipped with supporting disk 8 respectively, and each 8 below of supporting disk are connected with drive mechanism simultaneously, and supporting disk 8 is used for the fixed test box body 3 of installation, and supporting disk 8 is connected for dismantling with test box body 3, makes test box body 3 change convenient, and 8 upper surfaces of supporting disk open there is draw-in

groove

9, 3 lower extreme joints. The setting of serpentine circuit 21 has effectively increased the dwell time of blood sample at accuse temperature portion for blood sample reaches the optimum temperature of mixing with reagent before getting into test chamber 6, meanwhile, place the in-process and start drive mechanism, make its top supporting disk 8 drive the motion of test box body 3, improve the mobility of the fluidic in test chamber 6, blood sample and chemical reagent's mixed effect has effectively been improved, it shakes evenly to replace the manual work, when improving work efficiency, ensure that the testing result is reliable, it is accurate, thereby the coagulation parameter that more accurate aassessment comes from experimenter blood sample.

According to the above embodiment, preferably, the temperature control portion is communicated with a plurality of test chambers 6, each test chamber 6 is arranged in parallel, each test chamber 6 is communicated with the hydrophobic filter 17, different types of reagents including abciximab, cytochalasin D, kaolin, diatomite, thrombin, adenosine diphosphate and the like are placed in each test chamber 6 according to test requirements, and interact with a blood sample in each test chamber 6 to test and analyze different coagulation parameters, so that the detection efficiency is improved.

According to the above embodiment, preferably, the transmission mechanism includes a gear ring 10, a central gear 15, internal gears 12, a connecting plate 13, a rotating shaft 16 and a motor 14, the central gear 15 is disposed in the gear ring 10 and is concentrically disposed with the gear ring 10, three internal gears 12 are respectively engaged between the central gear 15 and the gear ring 10, the middle portion of each internal gear 12 is upwardly and respectively fixedly connected with the middle portion of each supporting plate 8, the internal gears 12 are respectively connected with each other through the connecting plate 13, each connecting plate 13 is fixedly connected with the side wall of the rotating shaft 16, the lower end of the rotating shaft 16 is connected with the motor 14, the upper end of the rotating shaft 16 is rotatably connected with the middle portion of the central gear 15, in this example, the transmission mechanism is disposed in the base 11, the upper surface of the base 11 is open, the outer. The motor 14 is started to drive the rotating shaft 16 to rotate, at the moment, each connecting plate 13 fixedly connected with the rotating shaft 16 drives the three internal gears 12 to rotate around the central gear 15 rapidly, and the internal gears 12 rotate in the rotating process, so that the supporting plate 8 connected with the internal gears 12 drives the test box body 3 above the supporting plate to shake blood samples in the test box body evenly.

According to the above embodiment, preferably, the serpentine pipeline 21 is provided with a temperature sensor 18 at one end close to the pipette, the temperature sensor 18 is electrically connected with a heating controller 19, and the heating controller 19 is electrically connected with a heating pipe 20. In this embodiment, a temperature control device 7 is disposed at a position of one side of the testing box body 3 opposite to the temperature control portion, a control module and a heating controller 19 electrically connected to the control module are disposed in the temperature control device 7, and the control module monitors the temperature measured by the temperature sensor 18 to adjust the output power of the heating controller 19, so that the blood sample can meet the blood coagulation parameter detection requirement. Physiologically, the coagulation process is highly dependent on the temperature at which the coagulation process occurs, and the temperature sensor 18 can monitor the blood sample before entering the testing chamber 6, so that the temperature of the blood sample can be adjusted by adjusting the heating power of the heating pipe 20 according to the requirement of the coagulation detection by a worker, the mixing of the blood sample and the reagent is accelerated, and the detection result is prevented from being influenced.

According to the above embodiment, preferably, heat preservation 5 wraps the test chamber 6, and when waiting to detect the blood sample more, heat preservation 5 effectively keeps warm to the blood sample in the test chamber 6, avoids waiting for the room temperature to hang down in the testing process and leads to the blood sample to be inconsistent with the detection demand, prevents to appear the phenomenon that needs to gather again.

According to the above embodiment, preferably, the temperature control portion is isolated from the test box body 3 by the thermal insulation layer 22, so as to prevent the heat of the temperature control portion from affecting the normal operation of other elements in the test box body 3.

The setting of serpentine circuit 21 has effectively increased the dwell time of blood sample at accuse temperature portion for blood sample reaches the optimum temperature of mixing with reagent before getting into test chamber 6, meanwhile, place the in-process and start drive mechanism, make its top supporting disk 8 drive the motion of test box body 3, improve the mobility of the fluidic in test chamber 6, blood sample and chemical reagent's mixed effect has effectively been improved, it shakes evenly to replace the manual work, when improving work efficiency, ensure that the testing result is reliable, it is accurate, thereby the coagulation parameter that more accurate aassessment comes from experimenter blood sample.

The foregoing is only a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, a plurality of modifications and decorations can be made without departing from the principle of the present invention, and these modifications and decorations should also be regarded as the protection scope of the present invention.

Claims

1. The utility model provides a blood coagulation parameter detects uses test box, its characterized in that, includes the test box body and locates the drive mechanism of test box body below, the test box body is provided with 3, and the test box body includes the box body, communicates in proper order sample inlet port, accuse temperature portion, test chamber, hydrophobic filter and vacuum port on the box body, the position rigid coupling in the relative test chamber in box body surface has a positioning substrate, positioning substrate is equipped with the couplant layer outward, accuse temperature portion includes serpentine pipe, wraps up the stopping outside serpentine pipe and locates the heating pipe in the stopping, serpentine pipe one end is linked together through advancing appearance pipe and sample inlet port, and the serpentine pipe other end is linked together through pipette and test chamber, each test box body below is equipped with the supporting disk respectively, and each supporting disk below is connected with drive mechanism simultaneously.

2. The blood coagulation parameter detection test cassette according to claim 1, wherein the temperature control portion is in communication with a plurality of test chambers, each of the test chambers is arranged in parallel, and each of the test chambers is in communication with a hydrophobic filter.

3. The blood coagulation parameter detection test box according to claim 2, wherein the transmission mechanism comprises a gear ring, a central gear, internal gears, a connecting plate, a rotating shaft and a motor, the central gear is arranged in the gear ring and concentric with the gear ring, three internal gears are respectively engaged between the central gear and the gear ring, the middle part of each internal gear is upwards and respectively fixedly connected with the middle part of each supporting plate, the internal gears are respectively connected with each other through the connecting plate, each connecting plate is fixedly connected with the side wall of the rotating shaft, the lower end of the rotating shaft is connected with the motor, and the upper end of the rotating shaft is rotatably connected with the middle part of the central gear.

4. The blood coagulation parameter detection test cassette of claim 3, wherein a temperature sensor is disposed at an end of the serpentine pipeline close to the pipette, the temperature sensor is electrically connected to a heating controller, and the heating controller is electrically connected to the heating pipe.

5. The blood coagulation parameter detection test kit according to claim 4, wherein the test chamber is wrapped with an insulating layer.

6. The blood coagulation parameter detection cartridge according to any one of claims 1 to 5, wherein the temperature control unit is isolated from the cartridge body by a heat insulating layer.