CN210923458U - Full-automatic detector - Google Patents

Full-automatic detector Download PDF

Info

Publication number
CN210923458U
CN210923458U CN201921174947.9U CN201921174947U CN210923458U CN 210923458 U CN210923458 U CN 210923458U CN 201921174947 U CN201921174947 U CN 201921174947U CN 210923458 U CN210923458 U CN 210923458U
Authority
CN
China
Prior art keywords
sample
reaction
reagent
cuvette
arm
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201921174947.9U
Other languages
Chinese (zh)
Inventor
邬荣杰
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NINGBO YIJIE BIOLOGICAL SCIENCE & TECHNOLOGY CO LTD
Original Assignee
NINGBO YIJIE BIOLOGICAL SCIENCE & TECHNOLOGY CO LTD
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by NINGBO YIJIE BIOLOGICAL SCIENCE & TECHNOLOGY CO LTD filed Critical NINGBO YIJIE BIOLOGICAL SCIENCE & TECHNOLOGY CO LTD
Application granted granted Critical
Publication of CN210923458U publication Critical patent/CN210923458U/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations

Landscapes

  • Physics & Mathematics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

A full-automatic detector comprises a module for automatically loading a cuvette, a reagent tray, a sample rack, a reaction tray, a sample adding arm with a reagent arm and a sample arm, and a detection unit. The full-automatic detector injects a sample into a cuvette of a reaction tray in an automatic sampling mode, automatically adds a reagent required to react according to the type of the sample, and detects the absorbance of a reaction solution in the cuvette by an optical measuring unit arranged below the cuvette of the reaction tray after the sample reacts with the reagent to form the reaction solution, so that the concentration of the sample can be directly obtained.

Description

Full-automatic detector
Technical Field
The present invention relates to a sample testing apparatus, and more particularly to a fully automatic testing apparatus for testing the concentration of a sample to continuously analyze a large number of samples without interruption.
Background
An analyzer for clinical examination is generally used for qualitative and quantitative measurement of a specific component in a biological sample such as blood or urine. In a general operation of an analyzer, a sample container is first dispensed into a reaction container through a sample nozzle. Further, a reagent is dispensed from a reagent container into a reaction container into which a sample is dispensed through a reagent nozzle, and the reagent is stirred. Then, the reagent and the specimen in the reaction container are allowed to react for a predetermined time to form a reaction solution. Then, the reaction solution is detected, and the concentration is calculated from the detection results, for example, information such as the absorbance and the luminescence amount.
In recent years, in order to prevent a medical accident, that is, a reagent container is filled incorrectly and/or a reagent container of another item is installed at a place where the reagent container should be installed, which may cause a subsequent measurement error, damage to a specimen sample and an error in measurement information of the specimen sample, which may easily cause a medical misdiagnosis or medical negligence. Therefore, in order to improve the above-mentioned deficiency, the traceable label such as a barcode can be used for each reagent container, and the reagent is used in a disposable manner so as to prevent the reagent from being deteriorated or deteriorated even if the reagent is stored for a long time, and so as not to add the reagent to the used reagent.
Generally, after a batch of sample samples is measured, an operator calculates the amount of reagent required for the next batch of sample samples, and sets the calculated amount in the analyzer. Sometimes, a plurality of reagents are used for each item, and therefore, it takes much labor and time to confirm the amount of the reagents used and to set the reagents in the analyzer. In addition, in order to use the replaced reagent container for actual inspection, it is necessary to create a calibration curve for each reagent container to confirm whether or not the reagent in the reagent container can be inspected.
SUMMERY OF THE UTILITY MODEL
The utility model discloses a main aim at discloses a full automatic detector, the module that has the automatic loading cell, can realize automatic mode and pour into the cell of examining the body sample in the reaction disc, and come the automatic reagent that needs react that adds according to the kind of examining the body sample, after examining body sample and reagent reaction formation reaction liquid, the detection of inhaling luminance is carried out to the reaction liquid in the cell by the optics measuring unit that sets up in the cell below of reaction disc, and can directly obtain the concentration of examining the body sample, thereby reach the purpose of full automated inspection and computational result.
Another object of the present invention is to disclose a full automatic detector, which can save manpower without manual operation, and can avoid the loss of manual operation and the contamination of human factors, so as to improve the detection accuracy of the sample, and facilitate the medical staff to make correct diagnosis.
Still another object of the utility model is to disclose a full automatic detector, adopt the reaction disc that has a plurality of passageways, and be provided with a plurality of reaction discs that have a plurality of passageways in reaction disc conveying mechanism, the cell has set up in advance on each reaction disc, after the cell on the reaction disc that has a plurality of passageways has been drawn and has finished, reaction conveying mechanism can be automatic in with mechanical parking area, parking platform can the vertical direction and the concept of controlling the direction change, the reaction disc that will draw the cell and finish is by the top downstream, and the reaction disc rebound that will place the cell is to the top, let reaction cup transfer arm take, can a large amount of specimen samples of continuous analysis by this, and can not be interrupted, also need not change or add reaction disc and cell always.
Still another aim at discloses a full automatic detector, detecting element directly sets up in the reaction disc below of the splendid attire load cell, make the physical sample that has added reagent need not utilize other robotic arm to come the cell to draw and remove to optical analysis device and carry out the measuration of inhaling luminance, can solve in prior art by this, in order to measuration the luminance of inhaling of reaction liquid and set up another robotic arm and draw the cell, and reduce full automatic detector's processing procedure cost, also can avoid simultaneously drawing the in-process of cell, because robotic arm's vibration causes the reaction liquid blowout in the cell and pollutes other physical samples or the reagent that is carrying out the analysis, can improve the accuracy of measurationing of physical sample by this.
According to the above-mentioned purpose, the utility model discloses a full automatic detector has the module of automatic loading cell, more includes reagent dish, sample frame, reaction dish, reaction cup transfer arm, has application of sample arm and the detecting element of reagent arm and sample arm. The module for automatically loading the cuvette comprises a plurality of reaction racks, a reaction rack conveying mechanism and a cuvette transfer arm, wherein each reaction rack is provided with a plurality of channels, and each channel is provided with a cuvette; the reaction frame conveying mechanism is used for placing a plurality of reaction frames, and the reaction frame conveying mechanism is used for moving the reaction frames in the vertical direction and the left-right direction in the full-automatic detector. The reagent tray is provided with reagent positions for placing reagent tubes, and the same or different reagents are respectively placed in the reagent tubes; the sample rack is used for placing a sample tube filled with a sample of a specimen; the reaction disc is provided with a plurality of channels which are used for placing the colorimetric cups and penetrate through the reaction disc from top to bottom; the reaction cup transfer arm is used for extracting and moving the cuvette arranged on the reaction frame to the upper part of the reaction disc and then placing the cuvette in the channel on the reaction disc; the sample adding arm comprises a reagent arm and a sample arm, wherein the reagent arm sucks a reagent in a reagent tube on the reagent tray by using a dropper, moves the dropper with the reagent sucked on to a cuvette of the reaction tray, and injects the reagent into the cuvette, and the sample arm sucks a sample in a sample tube on the sample rack by using the dropper, moves the dropper with the sample sucked on to the upper part of the cuvette of the reaction tray, injects the sample into the cuvette, so that the reagent and the sample react in the cuvette to form a reaction solution; and the detection unit is arranged below the channel of the reaction disc, and is provided with a photometric light source which irradiates the reaction liquid in the cuvette in the channel of the reaction disc above the detection unit to obtain the absorbance of the reaction liquid.
Drawings
Fig. 1 is a block diagram illustrating a fully automatic inspection machine according to the disclosed technology.
Fig. 2 is a side view of a fully automated inspection machine according to the teachings of the present invention.
Fig. 3A is a top view of a fully automated inspection machine according to the teachings of the present invention.
Figure 3B is a top view of a reaction rack with multiple channels on the reaction rack showing cuvettes loaded into the module according to the techniques disclosed herein.
Fig. 4 is a flow chart illustrating the operation steps of a fully automatic inspection machine according to the disclosed technique.
Detailed Description
In order to make the objects, technical features and advantages of the present invention more comprehensible to those skilled in the relevant art and to enable implementation of the present invention, accompanying drawings are provided herein to illustrate technical features and embodiments of the present invention, and preferred embodiments are further described. The drawings referred to below are for illustrative purposes only and are not necessarily drawn to scale. The description of the embodiments related to the present invention will not be repeated, except for those skilled in the art.
Please refer to fig. 1 in conjunction with fig. 2, fig. 3A and fig. 3B. Fig. 1 is a schematic diagram showing the block of the fully automatic detecting instrument disclosed in the present invention, fig. 2 is a schematic diagram showing the side view of the fully automatic detecting instrument disclosed in the present invention, fig. 3A is a schematic diagram showing the fully automatic detecting instrument disclosed in the present invention, and fig. 3B shows the reaction frame for bearing the cuvette, and the reaction frame has a top view of a plurality of channels.
In fig. 1, the fully automatic measuring apparatus 1 includes at least a reaction rack transport mechanism 12, a reaction rack 10, a reagent tray 30, a sample rack 40, a reaction tray 20, a cuvette transfer arm 14, a sample application arm composed of a reagent arm 60 and a sample arm 42, and a measuring unit 70, and the functions of each of these components are described in detail below.
The automatic cuvette loading module comprises a reaction rack 10, a reaction rack conveying mechanism 12 and a reaction cup transfer arm 14.
The reaction rack 10 is a carrier for carrying a plurality of cuvettes 102, the reaction rack 10 is provided with a plurality of channels 101, the number of the channels on the reaction rack may be 16, 25, 36, 64 or 96, and the reaction rack may be designed according to the user's requirement, that is, when the user needs to test and analyze a large number of samples (sample), in order to save time and manpower cost, a corresponding number of cuvettes 102 may be carried by a number of reaction racks 10 with more channels.
The reaction rack conveying mechanism 12 is used for placing a plurality of reaction racks 10 and conveying the reaction rack 10 carrying a plurality of cuvettes 102 in the fully automatic inspection apparatus 1, so as to provide the cuvette transfer arm 14 to extract the cuvette 102 from the reaction rack 10 onto the reaction tray 20 for use.
In the embodiment of the present invention, the operation concept of the reaction rack conveying mechanism 12 is similar to the concept of the mechanical parking lot, the reaction rack conveying mechanism 12 is provided with a bearing frame (not shown in the figure) (can be regarded as a parking platform of the mechanical parking lot), the bearing frame can move in the directions of one side of the machine of the fully automatic detector 1 above and below (i.e. the Y coordinate direction in fig. 2 and 3A), and front and back (i.e. the Z coordinate direction in fig. 2 and 3A), that is, the reaction racks 10 containing the cuvettes 102 are disposed on the bearing frame of the reaction rack conveying mechanism 12, and the reaction racks 10 containing the cuvettes 102 can move in the directions of one side of the machine of the fully automatic detector 1 above and back along with the bearing frame of the reaction rack conveying mechanism 12. It should be noted that the upper, lower, front and rear are relative positions when the user stands in front of the reaction rack transport mechanism 12 of the fully automatic testing machine 1 and faces the entire fully automatic testing machine 1.
In the present invention, the number of the loading frames for placing the reaction frames 10 in the reaction frame conveying mechanism 12 can be 4 or 6, that is, the reaction conveying mechanism 12 can load 4 or 6 reaction frames 10. In the preferred embodiment of the present invention, 4 carriers are used to carry 4 reaction racks 10, but may be added to carry more reaction racks 10 as required by the user. The 4 reaction shelves 10 are respectively disposed at the upper, lower, front and rear positions in a side of the machine platform of the fully automatic detector 1. When the cuvettes 102 in the reaction rack 10 above the platform of the automatic measuring apparatus 1 are completely used and the next cuvette 102 is to be continuously used, the reaction rack conveying mechanism 12 is activated to move the carriage carrying the empty reaction rack 10 (i.e. the cuvettes 102 are completely used) toward the lower side (Y-coordinate direction) of the automatic measuring apparatus 1 away from the platform of the automatic measuring apparatus 1 and move the reaction rack 10 carrying the cuvette 102 toward the user (Z-coordinate direction) at the rear side of the automatic measuring apparatus 1 (the position farther from the user in terms of the relative position of the user facing the automatic measuring apparatus 1) (Z-coordinate direction), the reaction rack 10 carrying the cuvette 102 is moved from the carriage of the reaction rack conveying mechanism 12 toward the user (Z-coordinate direction) (the position closer to the user in terms of the relative position of the user facing the automatic measuring apparatus 1), therefore, the transmission direction of the carrier in the reaction conveying mechanism 12 is in the counterclockwise direction, that is, the reaction rack 10 with the used cuvette 102 is conveyed to the lower portion of the machine table of the fully automatic measuring instrument 1, and the reaction racks 10 with the cuvettes 102 are all on the platform of the fully automatic measuring instrument 1, and the cuvette 102 is not required to be placed on the reaction rack 10 again until all cuvettes 102 loaded on all the reaction racks 10 are completely extracted.
The advantage of using the reaction transport mechanism 12 to transport the reaction rack 10 carrying cuvettes 102 in the fully automated inspection apparatus 1 is that: the number of cuvettes 102 to be used can be set on the reaction rack 10 at one time, which not only can prevent the cuvettes 102 from being contaminated by human beings in the detection process, but also can treat a large number of specimen samples in a batch mode, and has timeliness.
In another embodiment of the present invention, a warning device (not shown in the figures) is further disposed in the reaction conveying mechanism 12, and the warning device is used to remind the user that there is no cuvette 102 on the reaction rack 10 when the cuvettes 102 on all the reaction racks 10 in the reaction conveying mechanism 12 are taken out, i.e. it indicates that there is no cuvette available for the cuvette transfer arm 14 to take, and the warning device sends a message to remind the user that there is no cuvette 102 on the reaction rack 10, and the operation of the whole automatic detecting apparatus 1 is also suspended, so as to avoid that other components are still operated without the cuvette 102, and thus the sample and reagent are wasted. In a preferred embodiment, the warning device may be a buzzer to generate a sound to alert the user that the reaction disk 10 needs to be replaced.
The reaction tray 20 is provided with a plurality of channels 202 (shown in figure 3A) for placing the cuvettes 102. Wherein the reaction disk 20 is a circular disk on which a plurality of channels 202 are annularly arranged, the channels 202 are rectangular, preferably square, and the shape of the channels 202 mainly matches the shape of the cuvette 102. The utility model discloses in, the circumference of passageway 202 slightly is greater than the circumference of cell 102 for in the passageway 202 of reaction disc 20 can be put into to cell 102, and by the cell 102 the bottom up at least 1cm highly can expose in the below (Y coordinate direction) of passageway 202, in the more preferred embodiment of the utility model, expose cell 102 bottom in the passageway 202 below at least 1 cm's of reaction disc 20 aim at, still be provided with detecting element 70 in the below of reaction disc 20, the photometry light source that detecting element 70 launched must just can inhale the measurationof luminance through the reaction liquid of at least 1cm height, and the height of cell 102 towards reaction disc 20 open-ended is higher than the degree of depth of passageway 202, and its purpose is snatched by the rim of a cup of cell 102 in order to let reaction cup transfer arm 14, and can conveniently draw and place cell 102.
The reagent disk 30 has a plurality of reagent positions 302 for placing the reagent tubes 310, wherein the reagent tubes 310 store the same or different reagents, and it should be noted that, the utility model discloses a full-automatic detector 1 can also analyze and detect the sample of liver function, kidney function, myocardial enzyme, diabetes, blood fat, pancreatitis, ion type besides detecting protein, so reagent tubes 310 containing the same or different reagents can be set on the reagent positions 302 of the reagent disk 30 corresponding to different detection items.
The sample rack 40 is used for placing a sample tube 402 containing a sample, and the sample rack 40 is placed on the sample injection mechanism 50, so that the sample rack 40 can move in the front and back directions (Z coordinate direction) and the left and right directions (X coordinate direction) on the sample injection mechanism 50, and the sample arm 42 can take the sample contained in the sample tube 402 from the sample rack 40. It should be noted that the moving direction of the sample rack 40 on the sample injection mechanism 50 is indicated by the relative position of the user facing the reaction rack transportation mechanism 12 of the fully automatic testing machine 1, that is, the sample injection mechanism 50 moving the sample rack 40 forward or backward means that the sample injection mechanism 50 moves forward or backward on the platform of the fully automatic testing machine 1 in the Z coordinate direction.
In the operation of the sample injection mechanism 50, a user places a sample tube 402, which is required to be tested and contains a sample of a sample, on the sample holder 40, and then places the sample holder 40 on the sample injection mechanism 50, so that the sample injection mechanism 50 can drive the sample holder 40 to move on the platform of the fully automatic testing apparatus 1, when the sample arm 42 needs to extract the sample of the sample, the sample injection mechanism 50 drives the sample holder 40 to move to a positioning point (not shown in the figures) so that the sample arm 42 can extract the sample of the sample in the sample tube 402, and when the sample arm 42 needs to extract a next sample of the sample, the sample injection mechanism 50 drives the sample holder 40 to move to the positioning point, and at this time, the positioning point is aligned with a next sample tube 402 with the sample of the sample, rather than a previous sample tube 402 with the sample of the sample already extracted, and the repeated sampling of the sample in the same sample tube 402 can be avoided through the sample injection operation of the sample injection, the repeated operation causes the data to be repeated, and avoids the waste of reagents or sample samples.
In addition, in the embodiment of the present invention, a sensing device (not shown) is further disposed between the sample arm 42 and the sample injection mechanism 50. When the sample feeding mechanism 50 drives the sample rack 40 to the positioning point, the sensing device on the sample feeding mechanism 50 transmits a positioning signal to the sample arm 42, specifically, after the sample tube 402 to be sampled and analyzed reaches the positioning point, the sensing device (not shown in the figure) disposed in the sample arm 42 starts to move toward the sample tube 402 disposed at the positioning point after receiving the positioning signal, and inserts the dropper 422 disposed on the sample arm 42 into the sample tube 402 from top to bottom (Y coordinate direction) above the sample tube 402 to suck a sufficient amount (volume) of the sample, after the sample arm 42 sucks the sample, the dropper 422 sucks the sample away from the sample tube 40 from bottom (Y coordinate direction), and then the sample arm 42 moves the dropper 422 sucking the sample to the cuvette 102 on the reaction disk 20 to inject the sample into the cuvette 102, so as to achieve the purpose of automatic sampling.
The sample application arm, which is composed of the reagent arm 60 and the sample arm 42, the sample arm 42 is already mentioned above, and will not be further described here. The reagent arm 60 aspirates the reagent in the reagent tube 310 provided in the reagent disk 30 by the pipette 602 and injects the aspirated reagent into the cuvette 102 provided in the reaction disk 20, and the sample arm 42 aspirates the specimen sample from the sample tube 402 and injects the specimen sample into the cuvette 102 of the reaction disk 20, and at this time, the reagent and the specimen sample are contained in the cuvette 102, and the specimen sample and the reagent form a reaction solution in the cuvette 102.
The detecting unit 70 is disposed below the reaction tray 20, and the detecting unit 70 has a photometric light source for illuminating the reaction solution in the cuvette 102 in the channel 202 of the reaction tray 20 above the detecting unit 70, so that the absorbance of the reaction solution can be obtained.
The utility model discloses in, detecting element 70 is the spectral brightness device, and its wavelength range is 340nm-800nm, can set for the wavelength of measurationing the absorptiveness according to the project that will detect moreover, therefore the user also need not change the optical detector 70 that has different wavelengths because the project that the previous batch detected is different with the project that next batch detected, only need adjust the wavelength of the photometry light source of optical detector 70 before detecting can.
The embodiment of the utility model provides an in, full automatic detector 1 is still including the stirring arm 80, and this stirring arm 80 is connected with stirring rod 802 in Y coordinate direction for after aforementioned reagent and the appearance sample of examining all pour into cell 102, in order to let reagent and the appearance sample of examining react completely, can utilize stirring arm 80 to drive stirring rod 802 and stir in cell 102, react with the appearance sample of examining with higher speed reagent. It should be noted that, in a preferred embodiment of the present invention, the surface of the stirring rod 802 is a smooth surface, and when the reagent and the sample are stirred, no liquid adheres to the surface of the stirring rod 802, so that the volume of the reaction solution is not reduced.
In addition, in another preferred embodiment of the present invention, the fully automatic detecting apparatus 1 further comprises a cleaning tank 90, wherein the cleaning tank 90 is used for cleaning the stirring rod 802 to prevent the previous reaction solution from remaining on the stirring rod 802 and affecting the accuracy of the next reaction solution. Similarly, since the surface of the stirring rod 802 is smooth, the cleaning liquid does not remain on the surface of the stirring rod 802 even after the stirring rod 802 is cleaned. In the embodiment of the present invention, the cleaning solution may be ethanol, deionized water or distilled water. In another preferred embodiment, the cleaning tank 90 is connected to a water tank (not shown) through a water pipe (not shown), and the cleaning solution in the cleaning tank 90 is periodically and automatically replaced through the water pipe and the water tank, so that the stirring rod 802 is ensured not to remain the previous reaction solution to contaminate the next reaction solution during the detection of a large number of sample samples, and the cleaning solution is also ensured not to remain on the surface of the stirring rod 802 after the stirring rod 802 is cleaned.
Please refer to fig. 4. FIG. 4 is a flow chart illustrating the operation steps of the fully automatic inspection apparatus. In describing the operation procedure flowchart of fig. 4, the description will be made with reference to fig. 1, fig. 2, fig. 3A, and fig. 3B. Step 902: and starting the reaction cup transfer frame, taking a certain number of cuvettes from the reaction frame, and placing the cuvettes on the reaction disc. In this step, the user needs to put the reaction racks 10 carrying the cuvettes 102 on the reaction rack transport mechanism 12 in advance, and in the embodiment of the present invention, the reaction racks 10 carrying the cuvettes 102 are usually provided directly by the manufacturer, and of course, the user can fill the reaction racks by himself, but the latter is labor-consuming and time-consuming for the user, and generally the manufacturer provides the reaction racks 10 already containing the cuvettes 102 and uses the reaction racks directly.
Then, in step 904, the sample arm is activated to take the sample of the specimen in the sample tube 402 on the sample injection mechanism and place the sample in the cuvette on the reaction tray. In this step, a pipette 422 is connected to the sample arm 42 to pipette the sample in the sample tube 402, and the sample arm 42 transfers the sample to be injected into the cuvette 102.
And 906, starting the reagent arm to extract the reagent in the reagent tube on the reagent tray, and placing the reagent in the cuvette on the reaction tray so that the reagent reacts with the sample to form a reaction liquid.
And 908, starting a stirring arm to stir the reaction liquid in the cuvette on the reaction disk by using a stirring rod so that the reagent and the sample are reacted and uniformly mixed. This step is optional, but in order to allow the reagent and the specimen to react completely and to be mixed uniformly, this step is still performed in the present invention, the stirring time of the stirring rod 802 in the cuvette 102 is about 1-3 seconds, and because the diameter of the cuvette 102 is not large, the problem that the solution in the cuvette 102 will overflow when the stir bar 802 is received in the cuvette 102 is also considered, thus, the stir bar 802 does not extend entirely into the cuvette 102, only a portion of the stir bar 802 extends into the cuvette 102 to contact the solution, then stirring is carried out at a stirring speed of low rotation speed, and the purpose of the stirring speed of low rotation speed in the step is to avoid too high stirring speed, thereby spraying the reaction solution in the cuvette 102 and preventing the stirring rod 802 from colliding with the cuvette 102 to cause the cuvette 102 and/or the stirring rod 802 to be broken or broken.
And 910, detecting the brightness of the reaction liquid in the cuvette by using a detection unit positioned below the reaction disc, and outputting the detection result. In this step, the cuvette 102 containing the reaction solution is illuminated by the photometric light source (not shown) of the detecting unit 70 to obtain the absorbance of the reaction solution, and the absorbance of the sample is calculated and converted into concentration by the computing module (not shown) of the detecting unit 70, wherein the concentration can be the concentration of nucleic acid or protein. And the calculated concentration value may be outputted via an output device (not shown in the figure) connected to the fully automatic detector 1. Specifically, the output device is connected to the detecting unit 70, and the output device includes a printer, an external storage device, a calculator or a server.
Then, in step 912, the cuvette transfer arm is started to extract the cuvette with the detected absorbance and place the cuvette in a waste liquid recycling bin for collection. In this step, after the reaction liquid in the cuvette 102 on the reaction tray 20 has been subjected to the measurement of the absorbance, the cuvette transfer arm 14 is moved toward the upper side of the reaction tray 20 and grips the cuvette 102 having been subjected to the measurement of the absorbance, and the cuvette 102 containing the reaction liquid is placed in a waste liquid collection tub (not shown).
Therefore, the fully automatic measuring apparatus 1 can perform the operations of repeating the steps 902 to 912, and can perform the operations of fully automatically, massively and continuously outputting the detection results regardless of the sample, the reagent, the cuvette 102, the reaction solution, the detected cuvette 102 and the detection result, thereby saving the labor and reducing the possibility of cross contamination of the sample caused by manual operations.
Optionally, in another embodiment of the present invention, a step 905 is added between step 904 and step 906: the absorbance of the specimen sample (to which the reaction solution has not been added at this time) in the cuvette 102 is detected by a detection unit located below the reaction disk, and blank absorbance data of the specimen sample is obtained. The detecting unit 70 further includes a storage module (not shown in the figure), and the storage module stores a preset blank luminance threshold. The operation module (not shown in the figure) in the detection unit 70 compares the detected blank absorption luminance data with a blank absorption luminance threshold, determines whether the blank absorption luminance data of the sample exceeds a preset blank absorption luminance threshold, and outputs the result via an output device (not shown in the figure) connected to the fully automatic detector 1. The detection personnel are helped to judge, abnormal detection samples are eliminated, and the accuracy of the detection result is further improved.
The above description is only a preferred embodiment of the present invention, and is not intended to limit the scope of the present invention; while the invention has been described with reference to exemplary embodiments, it will be understood by those skilled in the art that various changes in form and details may be made therein without departing from the spirit and scope of the invention as defined by the appended claims.

Claims (7)

1. A full-automatic detector is characterized by comprising a module for automatically loading a cuvette, a detection unit and
the reagent tray is provided with reagent positions for placing reagent tubes, and the same or different reagents are respectively placed in the reagent tubes;
the reaction disc is provided with a plurality of channels for placing the colorimetric cups;
a sample application arm including a reagent arm and a sample arm, the reagent arm sucking a reagent in a reagent tube on the reagent tray by using a dropper, moving the dropper sucked with the reagent to the cuvette of the reaction tray, and injecting the reagent into the cuvette, and the sample arm sucking a sample to be tested by using a dropper, moving the dropper sucked with the sample to be tested to a position above the cuvette of the reaction tray, and injecting the sample to be tested into the cuvette, so that the reagent and the sample to be tested react in the cuvette to form a reaction solution;
the detection unit is arranged below the reaction disc.
2. The fully automated apparatus according to claim 1, wherein the module for automatically loading cuvettes comprises:
the cuvette fixing device comprises a plurality of reaction frames, a plurality of fixing devices and a cuvette fixing device, wherein each reaction frame is provided with a plurality of channels, and each channel is provided with the cuvette;
the sample arm can suck the sample of the specimen in the sample tube on the sample rack by using the dropper;
the reaction rack conveying mechanism is used for placing a plurality of reaction racks and is used for moving the reaction racks in the full-automatic detector in the vertical direction and the left-right direction;
and the reaction cup transfer arm is used for taking the cuvette from the reaction frame to the reaction disc for use.
3. The apparatus of claim 2, further comprising a sample feeding mechanism for carrying the sample rack and moving the sample rack in forward, backward, left, and right directions on the same plane on the sample feeding mechanism.
4. The automatic testing apparatus according to claim 1, wherein said testing unit has a photometric light source that illuminates said reaction solution in said cuvette in said channel of said reaction disk above said testing unit.
5. The fully automatic detector according to claim 1, wherein said detection unit further comprises an arithmetic module.
6. The automatic detector of claim 1, wherein the detecting unit is a spectral brightness device.
7. The automatic testing apparatus according to claim 1, further comprising a stirring arm, wherein a stirring rod is connected to the stirring arm, such that the stirring arm can stir the cuvette containing the reaction solution by using the stirring rod.
CN201921174947.9U 2018-12-11 2019-07-24 Full-automatic detector Active CN210923458U (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN2018115098227 2018-12-11
CN201811509822.7A CN109324002A (en) 2018-12-11 2018-12-11 A kind of full-automatic detector

Publications (1)

Publication Number Publication Date
CN210923458U true CN210923458U (en) 2020-07-03

Family

ID=65256078

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201811509822.7A Pending CN109324002A (en) 2018-12-11 2018-12-11 A kind of full-automatic detector
CN201921174947.9U Active CN210923458U (en) 2018-12-11 2019-07-24 Full-automatic detector

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CN201811509822.7A Pending CN109324002A (en) 2018-12-11 2018-12-11 A kind of full-automatic detector

Country Status (1)

Country Link
CN (2) CN109324002A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110387322A (en) * 2018-04-09 2019-10-29 恺硕生物科技(厦门)有限公司 Automatic nucleic acid extracts detection system

Also Published As

Publication number Publication date
CN109324002A (en) 2019-02-12

Similar Documents

Publication Publication Date Title
JP5300447B2 (en) Automatic analyzer and sample dispensing method in automatic analyzer
JP5346807B2 (en) A device that automatically adjusts the bacterial inoculum level of a sample
US9581608B2 (en) Sample analyzer and method for controlling sample analyzer
JP5485766B2 (en) Sample rack transport system
US20160291048A1 (en) Automatic analysis device
WO2009110583A1 (en) Analysis apparatus and measurement unit
JP5815917B2 (en) Rack transport device
CN104272083A (en) System, apparatuses and devices for pretreating cells
JP5166208B2 (en) Sample analyzer, calibration method for sample analyzer, and computer program
US9213037B2 (en) Sample analyzer and sample analyzing method
US9500577B2 (en) Sample analyzer
WO2007139212A1 (en) Automatic analyzer
US20070183926A1 (en) Sample measuring apparatus
JP2010121936A (en) Specimen processing system
JP3990943B2 (en) Automatic analysis system
JP2011163909A (en) Automatic analyzer and washing method for dispensing means
US8778686B2 (en) Automatic analyzer and dispensing method thereof
CN113049800B (en) Immunoassay analyzer, detection method thereof and computer readable storage medium
CN210923458U (en) Full-automatic detector
JP4871025B2 (en) Automatic analyzer and its sample dispensing method
JP6952449B2 (en) Dispensing device with two temperature sensors
JP4045211B2 (en) Automatic analyzer
JP6121743B2 (en) Automatic analyzer
US8845964B2 (en) Sample analyzer and method for controling a sample analyzer
JP2011007697A (en) Autoanalyzer

Legal Events

Date Code Title Description
GR01 Patent grant
GR01 Patent grant