CN210903670U

CN210903670U - Tissue repair biomembrane skin patch

Info

Publication number: CN210903670U
Application number: CN201921382999.5U
Authority: CN
Inventors: 邹潮
Original assignee: Chengong Xiamen Bio Tech Co ltd
Current assignee: Chengong Xiamen Bio Tech Co ltd
Priority date: 2019-08-23
Filing date: 2019-08-23
Publication date: 2020-07-03
Anticipated expiration: 2029-08-23

Abstract

The utility model discloses a tissue repair biomembrane skin subsides, include from the top down and stack gradually fixed biomembrane, absorb water glue, absorb water pad and adhesive tape down, wherein: the biological film is used for covering the affected part of the sore opening, promoting the growth of new cells at the sore opening and isolating microorganisms to prevent the microorganisms from infecting the sore opening; the water absorption glue is used for fixing the biological membrane on the water absorption pad; the water absorption pad is larger than or equal to the area of the biological membrane and is used for absorbing tissue fluid or blood flowing out of the affected part of the sore; the adhesive plaster is arranged around the periphery of the water absorption pad and is used for fixing the integral tissue repair biological membrane patch on the affected part of the sore. The utility model has the advantages that the biological membrane is not easy to wrinkle and slide, is convenient for pasting operation, has simple use process and can avoid polluting microorganisms.

Description

Tissue repair biomembrane skin patch

Technical Field

The utility model relates to a membrane skin subsides, concretely relates to tissue repair biomembrane skin subsides.

Background

However, with the development of artificial tissue repair materials and related medical technologies, local repair of human tissues and organs becomes possible. Artificial tissue repair materials have become an essential medical device in modern surgery. Human tissue repair materials are used in a wide variety of applications, for example: the application in the fields of plastic cosmetology such as pleura and peritoneum repair, pericardium repair, hard brain/spinal membrane defect repair, bladder repair, hernia repair, female pelvic floor dysfunction disease repair, nerve conduit defect repair, blood vessel repair, ligament repair, breast augmentation and breast beautification and the like.

However, the materials currently used as tissue repair membranes are mainly: autologous tissues and synthetic high molecular polymers (such as nylon, dacron, silicon rubber and other polymers). The former has limited raw material sources, high price and difficult mass production; the latter has poor strength, hard and soft texture, poor biocompatibility, easy generation of foreign body sensation and pain, common erosion and infection complications, and can only be used for parts with low requirements on mechanical strength and comfort.

At present, there is a method for rapidly preparing a tissue repair biomembrane prepared by using a porcine intestinal submucosa (SIS) matrix, and the tissue repair biomembrane prepared by the method contains a natural extracellular matrix and a collagen structure in a complex arrangement, and is characterized in that:

1) the cell is convenient to attach, crawl and grow, and the tissue regeneration is promoted;

2) the vaccine has no immunogenicity, does not cause immunological rejection, and has good histocompatibility;

3) the film thickness is only 0.05mm, is thinner and more flexible than the common biological film with the thickness of 0.8mm, can be attached to the sore surface of any part and can maintain the corresponding tissue biomechanical requirement;

4) can isolate microbial infection.

However, most of the tissue repair biological membranes are very thin, the thickness of the membrane is only 0.05-0.8mm, and the membrane is transparent, soft and easy to wrinkle, is inconvenient to adhere and is easy to pollute microorganisms in the using process.

SUMMERY OF THE UTILITY MODEL

In order to solve the technical problem, an object of the present invention is to provide a tissue repair biofilm patch, which has the advantages of difficult wrinkling and slipping of the biofilm, convenient adhesion, simple use and capability of avoiding microbial contamination.

The adopted technical scheme is as follows:

the utility model provides a tissue repair biomembrane skin subsides, includes from top to bottom down stacks gradually fixed biomembrane, absorbs water and glues, absorbs water pad and adhesive tape, wherein:

the biological film is used for covering the affected part of the sore opening, promoting the growth of new cells at the sore opening and isolating microorganisms to prevent the microorganisms from infecting the sore opening;

the water absorption glue is used for fixing the biological membrane on the water absorption pad;

the water absorption pad has the area larger than or equal to the biological membrane and is used for absorbing tissue fluid or blood flowing out of the affected part of the sore;

the adhesive plaster is arranged around the periphery of the water absorption pad and is used for fixing the integral tissue repair biological membrane patch on the affected part of the sore.

Further, still include:

the sealing bag is used for pasting the integral tissue repairing biological film, comprises the biological film, the water absorption glue, the water absorption pad and the adhesive tape which are sequentially laminated and fixed, and is packaged in the sealing bag in an aseptic mode.

Furthermore, in 4 layers of the fixed biological membrane, the water-absorbing glue, the water-absorbing pad and the adhesive tape which are sequentially laminated, the surface area of the lower layer is larger than that of the upper layer in the upper and lower layers which are adjacent in pairs.

Further, the biofilm is a biofilm prepared with a porcine small intestine submucosa matrix.

Further, the thickness of the biological membrane is 0.01mm to 0.8mm, preferably 0.03mm to 0.08 mm.

Further, the shape of the biological membrane is rectangular, circular, elliptical or irregular.

Further, when the shape of the biological membrane is rectangular, the size of the biological membrane is 0.5cm × 1cm to 15cm × 30cm, and the width-length ratio is 1: 1 to 1: 10.

Further, the water-absorbing glue is coated on the water-absorbing pad, and the area of the water-absorbing glue is larger than or equal to that of the biological membrane.

As an alternative, the absorbent pad and the adhesive tape are replaced by a dark paper pad; namely, the tissue repair biological film patch comprises a biological film, a water-absorbing adhesive and a dark paper pad which are sequentially laminated and fixed from top to bottom.

As another alternative, the biological membrane can be replaced by a synthetic high molecular polymer (such as polymers of nylon, terylene, silicon rubber and the like) grid membrane.

The beneficial effects of the utility model reside in that:

because the existing biological membrane is of an ultrathin structure and is transparent, the biological membrane is difficult to clamp and is easy to lose and wrinkle when being taken by tweezers, and the biological membrane is easy to move and run even after being applied. However, the utility model discloses a setting is absorbed water and is glued, the pad and the adhesive tape absorb water for need not use tweezers during the use, aim at the sore with the biomembrane that tissue repair biomembrane skin pasted simply, cover whole tissue repair biomembrane skin paste in the affected part top, press the peripheral adhesive tape department of skin paste can. Therefore, the utility model is very convenient and simple to use, and the operation process is also favorable for avoiding the microbial pollution; more importantly, the utility model provides a biomembrane is fixed on the pad that absorbs water by the glue that absorbs water, is difficult for corrugating, slide, is favorable to newborn histiocyte to grow on it, and the pad that absorbs water can also absorb the interstitial fluid or the bloody water that the sore flows, and the glue that absorbs water will lose viscidity after meetting interstitial fluid or bloody water, when pad and adhesive tape are uncovered absorbing water like this, and the biomembrane can remain on the affected part tissue and can not adhere to the pad that absorbs water and be uncovered together to avoid the misery of affected part and biomembrane separation, also avoid microbial contamination.

Drawings

In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required to be used in the description of the embodiments or the prior art will be briefly described below, and it is obvious that the drawings in the following description are only embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to these drawings without inventive exercise.

Fig. 1 is a schematic top view of a tissue repair biofilm patch of example 1.

Fig. 2 is a schematic top view of a tissue repair biofilm patch of example 2.

Fig. 3 is a schematic top view of the tissue repair patch of example 4.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only preferred embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative efforts belong to the protection scope of the present invention.

Example 1

As shown in fig. 1, a tissue repair biofilm patch comprises a sealed bag, and a biofilm 10, a water-absorbent glue 20, a water-absorbent pad 30 and an adhesive plaster 40 which are sequentially laminated and fixed from top to bottom, wherein the biofilm 10, the water-absorbent glue 20, the water-absorbent pad 30 and the adhesive plaster 40 which are sequentially laminated and fixed form an integral tissue repair biofilm patch, and the integral tissue repair biofilm patch is aseptically packaged in the sealed bag 50. Wherein:

the biofilm 10 is preferably a biofilm prepared from porcine small intestine submucosa matrix, the thickness of the biofilm is 0.01mm to 0.8mm, preferably 0.03mm to 0.08mm, the shape of the biofilm includes, but is not limited to, a rectangle, a right circle, an ellipse or a special shape, the size of the biofilm can be designed according to the shape of the sore or can be customized according to the size of the sore, the area of the biofilm is capable of covering the whole sore and is equal to or larger than the area of the sore, the shape of the biofilm in the embodiment is selected to be a rectangle, the general size of the biofilm is 0.5cm × 1cm to 15cm × 30cm, the width-length ratio is 1: 1 to 1: 10, and the length and width of the rectangle can be selected, for example, the width and length of the rectangle are 10cm × 20 cm.

And the water absorption glue 20 is used for fixing the biological membrane on the water absorption pad and preventing the biological membrane from moving. The water absorption glue is coated on the water absorption pad, and the area of the water absorption glue is larger than or equal to that of the biological membrane. The water-absorbing glue is characterized in that: it loses viscosity when encountering interstitial fluid or blood. Thus, when the adhesive plaster is uncovered, the biological membrane can be kept in the tissues of the affected part and can not be attached with the water absorption pad to be uncovered, thereby avoiding the pain of the separation of the affected part and the biological membrane and avoiding the microbial pollution.

The absorbent pad 30, the area of which is larger than or equal to the biological membrane, is used for absorbing tissue fluid or blood flowing out from the affected part of the sore.

And the adhesive plaster 40 is arranged around the periphery of the water absorption pad and is used for fixing the integral tissue repair biological membrane patch on the affected part of the sore.

In a preferred embodiment, 4 layers of the fixed biological membrane, the absorbent glue, the absorbent pad and the adhesive fabric are sequentially laminated, and in the upper and lower two adjacent layers, the surface area of the lower layer is larger than that of the upper layer.

Or the surface area of the water absorption pad is larger than that of the biological membrane, the surface area of the adhesive fabric is larger than that of the water absorption pad, and the surface area of the water absorption adhesive is equal to that of the biological membrane.

Because the existing biological membrane is of an ultrathin structure and is transparent, the biological membrane is difficult to clamp and is easy to lose and wrinkle when being taken by tweezers, and the biological membrane is easy to move and run even after being applied. However, the tissue repair bio-film patch of this embodiment is provided with the water absorbent gel, the water absorbent pad and the adhesive tape, so that when in use, forceps are not needed, the bio-film on the tissue repair bio-film patch is simply aligned with the sore, the whole tissue repair bio-film patch is covered on the affected part, and the adhesive tape around the patch is pressed. Therefore, the tissue repair biological membrane patch is very convenient and simple to use, and the operation process is also beneficial to avoiding microbial pollution; more importantly, the biomembrane in the tissue repair biomembrane skin patch is fixed on the water absorption pad by the water absorption glue, is not easy to wrinkle and slide, is beneficial to the growth of new tissue cells on the water absorption pad, can absorb tissue fluid or blood water flowing out of a sore, and loses viscosity after encountering the tissue fluid or the blood water, so that when the water absorption pad and the adhesive tape are uncovered, the biomembrane can be kept on tissues of an affected part and cannot be attached to the water absorption pad to be uncovered together, thereby avoiding the pain of the separation of the affected part and the biomembrane, and avoiding microbial contamination.

Example 2

Referring to example 1, unlike example 1, referring to fig. 2, the outer shape of the biofilm of this example is an ellipse, and the major axis and the minor axis of the ellipse may be 10cm × 20cm, etc.

Example 3

Referring to example 1, unlike example 1, in this example, a synthetic polymer (e.g., nylon, dacron, silicon rubber, etc.) mesh membrane is selected instead of the biofilm.

Example 4

Referring to example 1, unlike example 1, this example uses a dark colored paper pad 60 instead of the absorbent pad 30 and the adhesive 40 of example 1, as shown in fig. 3. Thus, the tissue repair biofilm patch comprises a fixed biofilm 10, a water absorption glue 20 and a dark paper pad 60 which are sequentially laminated from top to bottom. The whole of the fixed biofilm 10, the water absorbent glue 20 and the dark paper pad 60 which are sequentially laminated is aseptically packaged in the sealed bag 50.

The dark paper pad is used for supporting the biological membrane, so that the biological membrane is more obvious on the dark paper pad (the biological membrane is very thin and transparent, and is easy to lose and wrinkle during operation).

In this example, the absorbent glue is used to secure the biofilm to the dark paper pad, preventing the biofilm from moving, so that when the dark paper pad is not needed, the transparent biofilm is visible (clearly visible and easily visible) on the dark paper pad, and the biofilm can be easily removed.

The present invention is described in detail with reference to preferred embodiment 1 to embodiment 2, and embodiment 1.

The above detailed description is only for the purpose of illustrating the practical embodiments of the present invention, and they are not intended to limit the scope of the present invention, and all equivalent embodiments or modifications that do not depart from the technical spirit of the present invention are intended to be included within the scope of the present invention.

Claims

1. The utility model provides a tissue repair biomembrane skin subsides which characterized in that includes from top to bottom and stacks gradually fixed biomembrane, the glue that absorbs water, water absorption pad and adhesive tape down, wherein:

the water absorption pad is larger than or equal to the area of the biological membrane and is used for absorbing tissue fluid or blood flowing out of the affected part of the sore;

2. The tissue repair biofilm patch of claim 1, further comprising:

3. The tissue repair biofilm patch according to claim 1, wherein 4 layers of fixed biofilm, water-absorbing adhesive, water-absorbing pad and adhesive tape are sequentially laminated, and the surface area of the lower layer is larger than that of the upper layer in two adjacent upper and lower layers.

4. The tissue repair biofilm patch of claim 1, wherein said biofilm is a biofilm prepared from a porcine small intestine submucosa matrix.

5. The tissue repair biofilm patch of claim 1, wherein said biofilm has a thickness of from 0.01mm to 0.8 mm.

6. The tissue repair biofilm patch of claim 5, wherein said biofilm has a thickness of from 0.03mm to 0.08 mm.

7. The tissue repair biofilm patch of claim 1, wherein said biofilm has an outer shape that is rectangular, right circular, elliptical or irregular.

8. The tissue repair biofilm patch of claim 7, wherein said biofilm has a rectangular configuration and a size of from 0.5cm × 1cm to 15cm × 30cm and a width to length ratio of from 1: 1 to 1: 10.

9. The tissue repair biofilm patch of claim 1, wherein said water-absorbent gel is coated on a water-absorbent pad, said water-absorbent gel having an area greater than or equal to an area of said biofilm.

10. The tissue repair biofilm patch of claim 1, wherein said absorbent pad and said adhesive are replaced with a dark paper pad; or the artificial synthesized high molecular polymer grid membrane is used for replacing the biological membrane.