CN210834936U

CN210834936U - Automatic biochemical analyzer

Info

Publication number: CN210834936U
Application number: CN201921676949.8U
Authority: CN
Inventors: 罗进才; 黄江航
Original assignee: Guangdong Muma Life Technology Co ltd
Current assignee: Guangdong Muma Life Technology Co ltd
Priority date: 2019-09-30
Filing date: 2019-09-30
Publication date: 2020-06-23
Anticipated expiration: 2029-09-30

Abstract

The utility model relates to the technical field of biochemical analysis, in particular to an automatic biochemical analyzer, which comprises a base, a feeding mechanism, a mixing mechanism and an analyzing mechanism, wherein the feeding mechanism, the mixing mechanism and the analyzing mechanism are arranged on the base; the material mixing mechanism is used for driving the clamping jig to rotate relative to the support plate; the analysis mechanism is used for detecting and analyzing the sample to be detected in the container member mixed by the mixing mechanism; when the sample to be tested needs to be subjected to biochemical analysis, the container part containing the sample to be tested is clamped on the clamping jig, the mixing mechanism drives the clamping jig to rotate, the rotating clamping jig drives the container part to rotate, so that the sample to be tested in the container part is automatically inverted and mixed, the feeding mechanism moves the sample to be tested mixed by the mixing mechanism to the analyzing mechanism, and the analyzing mechanism automatically analyzes the sample to be tested mixed by the mixing mechanism.

Description

Automatic biochemical analyzer

Technical Field

The utility model relates to a biochemical analysis technical field especially discloses an automatic biochemical analysis instrument.

Background

The biochemical analyzer is an instrument for detecting and analyzing vital chemical substances, and can provide important information basis for diagnosis, treatment, prognosis and health status of diseases clinically. The biochemical analyzer is an indispensable basic device in medical inspection laboratories, and clinical biochemical analyzers are mostly full-automatic or semi-automatic biochemical analyzers that adopt liquid reagent at present, and these biochemical analyzers all have a common characteristics and need adopt manual work or instrument to carry out operations such as application of sample, add reagent, mixing, washing reaction cup, washing application of sample needle, therefore or complex operation, or instrument structure is complicated, bulky, the operation is complicated, the price is expensive.

However, in the vast primary medical institutions (rural health centers, private clinics, primary communities, hospital bedside, emergency sites, animal clinics, etc.), due to the fact that many medical inspectors are non-professional, the amount of detection samples is small, the site and the cost are limited, and the like, an analysis instrument with simple structure, small volume, simple and convenient operation, quick report, low price and low failure rate is urgently needed to meet the requirement of rapid detection on the site.

SUMMERY OF THE UTILITY MODEL

In order to overcome the defects and deficiencies existing in the prior art, the utility model aims to provide an automatic biochemical analyzer with simple structure, small volume, simple operation and low price to meet the actual needs of medical institutions.

In order to achieve the above object, the present invention provides an automatic biochemical analyzer, comprising a base, a feeding mechanism, a mixing mechanism and an analyzing mechanism, wherein the feeding mechanism, the mixing mechanism and the analyzing mechanism are arranged on the base, the feeding mechanism comprises a support plate rotatably arranged with the base, a first driving member for driving the support plate to rotate, and a clamping jig rotatably arranged on the support plate, and the clamping jig is used for bearing external container parts; the material mixing mechanism is used for driving the clamping jig to rotate relative to the support plate so as to mix the sample to be detected and/or the reagent in the container part carried by the clamping jig; the analysis mechanism is used for detecting and analyzing the reagent in the container part before/after mixing by the mixing mechanism or the reaction product of the reagent and the sample to be detected.

Preferably, the mixing mechanism and the analysis mechanism are arranged around the support plate, the number of the clamping jigs is multiple, the multiple clamping jigs are arranged in an annular array around the rotation axis of the support plate, each clamping jig is used for bearing one container, the rotation axis of the support plate is arranged vertically, and the rotation axis of the clamping jig is arranged horizontally.

Preferably, the mixing mechanism comprises a second driving part arranged on the base and a rack connected with the output end of the second driving part, and the clamping jig is provided with a gear used for meshing with the rack.

Preferably, the base is provided with a sliding groove, the rack is slidably accommodated in the sliding groove, one end of the rack is connected with the output end of the second driving piece, and the other end of the rack is meshed with the gear through the sliding groove.

Preferably, the container member is made of a light-transmitting material, the analysis mechanism includes a light emitter and a light receiver disposed on the base, light emitted from the light emitter passes through a reagent in the container member or a reaction product of the reagent and a sample to be measured and irradiates the light receiver, and the light receiver is used for photoelectric conversion.

Preferably, the light emitter comprises a light source, a collimating lens, a light filter and a light hole, wherein the light source is a light generator capable of generating light with a wavelength of 300-800nm, the collimating lens is used for converting scattered light generated by the light source into parallel light, the light filter is an optical device for selecting a required radiation band, the light hole is positioned on a light path between the light source and the light receiver, and the light hole is used for preventing the light from being blocked; the base is provided with the support, and the support rotates and is provided with the layer board, and the support is equipped with and is used for driving layer board pivoted third driving piece, and the quantity of light filter is at least one, and the light filter sets up in the layer board, and during the detection, the light filter that third driving piece drive layer board made required use switches to in the middle of the light path at light source, collimating lens, light receiver place.

Preferably, the clamping jig is provided with a containing hole and a concave hole communicated with the containing hole, an elastic piece is arranged in the concave hole, the containing hole is used for containing the container piece, the elastic piece comprises a rolling ball and a spring, the rolling ball is contained in the concave hole, and the spring drives the rolling ball to protrude into the containing hole under the action of the elastic force to abut against the outer surface of the container piece.

Preferably, the carrier plate is provided with a heating sheet, and the heating sheet comprises a ring body and a plurality of strip bodies connected with the ring body; the support plate includes the base plate and the a plurality of extension arms of being connected with the base plate, and the base plate rotates and sets up in the base, and a plurality of extension arms set up around the axis of rotation of base plate, clamps the tool and rotates and set up between two adjacent extension arms, and the ring body sets up in the base plate, and the bar body sets up with the extension arm one-to-one, and the ring body sets up around the axis of rotation of base plate.

Preferably, the carrier plate is provided with a heating sheet, the heating sheet is accommodated in the carrier plate and is in close contact with the carrier plate, and the carrier plate and the clamping jig are both made of materials easy to transfer heat; the base is provided with a containing blind groove, and the support plate is contained in the containing blind groove; the support plate includes the base plate and the a plurality of extension arms of being connected with the base plate, and the base plate rotates and sets up in the base, and a plurality of extension arms set up around the axis of rotation of base plate, clamp the tool and rotate and set up between two adjacent extension arms.

Preferably, the automatic biochemical analyzer further comprises a code scanning mechanism, a pressing mechanism and a heat shield, wherein the code scanning mechanism and the pressing mechanism are arranged on the base, the code scanning mechanism, the mixing mechanism, the pressing mechanism and the analyzing mechanism are arranged around the support plate, the code scanning mechanism is provided with a code reader for reading codes on the container piece, the pressing mechanism is used for pressing the container piece to release pre-embedded reagents in the container piece, and the mixing mechanism drives the container piece to be reversely mixed through the clamping fixture; the heat shield is detachably connected with the base, and when the heat shield is connected with the base, the support plate and the heating sheet and the clamping jig on the support plate are positioned in a relatively closed space.

The utility model has the advantages that: when the sample to be tested needs to be subjected to biochemical analysis, the container part containing the sample to be tested or/and the reagent to be tested is clamped on the clamping jig, the mixing mechanism drives the clamping jig to rotate, the rotating clamping jig drives the container part to rotate, so that the sample to be tested or/and the reagent in the container part can be automatically inverted and mixed, and the mixing mechanism is used for driving the clamping jig to rotate relative to the support plate so as to mix the sample to be tested and/or the reagent in the container part carried by the clamping jig; the analysis mechanism is used for detecting and analyzing the reagent in the container part before/after mixing by the mixing mechanism or the reaction product of the reagent and the sample to be detected.

Drawings

Fig. 1 is a schematic perspective view of the present invention;

FIG. 2 is a schematic view of the exploded structure of the present invention;

fig. 3 is an exploded schematic view of the analysis mechanism of the present invention;

fig. 4 is an exploded schematic view of the clamping jig, the gear, the container and the elastic member of the present invention.

The reference numerals include:

1-feeding mechanism 2-mixing mechanism 3-analysis mechanism

4-carrier plate 5-clamping jig 6-container part

7-second driving member 8-rack 9-gear

11-chute 12-optical filter 13-light receiver

14-support 15-supporting plate 16-containing hole

17-rolling ball 18-spring 19-threaded column

21-first hole body 22-second hole body 23-heating piece

24-ring 25-strip 26-substrate

27-extension arm 28-blind hole 29-code sweeping mechanism

31-pressing mechanism 32-heat shield 33-accommodating blind groove

34-light source 35-collimating lens 36-light hole

111 — base.

Detailed Description

In order to facilitate understanding of those skilled in the art, the present invention will be further described with reference to the following examples and accompanying drawings, which are not intended to limit the present invention.

Referring to fig. 1 and fig. 2, an automatic biochemical analyzer of the present invention includes a base 111, a feeding mechanism 1, a mixing mechanism 2 and an analyzing mechanism 3 disposed on the base 111, the feeding mechanism 1 includes a support plate 4 rotatably disposed on the base 111, a first driving member for driving the support plate 4 to rotate, and a clamping fixture 5 rotatably disposed on the support plate 4, the first driving member includes a motor and a cam divider, the support plate 4 has a disc-like main body, the support plate 4 is mounted on an output shaft of the cam divider, and the motor drives the support plate 4 to intermittently rotate via the cam divider; the clamping jig 5 is used for bearing an external container part 6, and the container part 6 is used for containing a sample to be detected or/and a reagent; the mixing mechanism 2 is used for driving the clamping jig 5 to rotate relative to the support plate 4 so as to enable the reagent or/and the sample to be detected in the container part 6 carried by the clamping jig 5 to be reversely mixed; the analysis mechanism 3 is used for automatically detecting and analyzing the reagent in the container member 6 before/after mixing by the mixing mechanism 2 or the reaction product of the reagent and the sample to be detected.

When the biochemical analysis is needed to be performed on a sample to be detected, a container part 6 containing the sample to be detected or/and a reagent is clamped on a clamping jig 5, then a first driving part drives a carrier plate 4 to rotate, the rotating carrier plate 4 drives the clamping jig 5 to rotate together, so that the clamping jig 5 moves to a mixing mechanism 2, then the mixing mechanism 2 drives the clamping jig 5 to rotate, the rotating clamping jig 5 drives the container part 6 to rotate, the automatic reverse mixing of the sample to be detected or/and the reagent in the container part 6 is further realized, a feeding mechanism 1 moves the container part 6 mixed by the mixing mechanism 2 to an analysis mechanism 3, and the analysis mechanism 3 performs automatic analysis on the reagent mixed by the mixing mechanism 2 or a reaction product of the reagent and the sample to be detected.

The mixing mechanism 2 and the analysis mechanism 3 are arranged around the support plate 4, the number of the clamping jigs 5 is multiple, the plurality of clamping jigs 5 are in an annular array around the rotation axis of the support plate 4, each clamping jig 5 is used for bearing a container part 6, the rotation axis of the support plate 4 extends in the vertical direction, and the rotation axis of the clamping jig 5 extends in the horizontal direction. The number of the clamping jigs 5 is increased, so that the detection of the samples to be detected in the container pieces 6 is realized.

The mixing mechanism 2 includes a second driving member 7 disposed on the base 111, and a rack 8 connected to an output end of the second driving member 7, in this embodiment, the second driving member 7 is an air cylinder or an electric cylinder, the rack 8 is connected to a piston rod of the second driving member 7, the clamping fixture 5 is provided with a gear 9 for engaging the rack 8, preferably, the clamping fixture 5 is rotatably disposed with the support plate 4 via a shaft body, and the gear 9 is mounted on the shaft body. When the device is used, the second driving piece 7 drives the rack 8 to stretch and retract, so that the gear 9 is driven to rotate forwards and backwards, the gear 9 which rotates forwards and backwards drives the clamping jig 5 to rotate forwards and backwards, and then the sample to be detected or/and the reagent in the container piece 6 are reversely mixed.

The base 111 is provided with a sliding groove 11, the rack 8 is slidably accommodated in the sliding groove 11, one end of the rack 8 is connected with the output end of the second driving part 7, and the other end of the rack 8 is meshed with the gear 9 through the sliding groove 11.

Referring to fig. 1 to 3, the container member 6 is made of a transparent material, the analysis mechanism 3 includes a light emitter and a light receiver 13 disposed on the base 111, light emitted from the light emitter passes through the reagent or the reaction product of the reagent and the sample to be measured in the container member 6 and irradiates the light receiver 13, and the light receiver 13 is used for photoelectric conversion.

The light emitters can be constructed in a variety of ways, for example as follows: the light emitter comprises a light source 34, a collimating lens 35, a light filter 12 and a light hole 36, wherein the light source 34 is a light generator capable of generating light with a wavelength of 300-800nn, the collimating lens 35 is used for converting scattered light generated by the light source 34 into parallel light, the light filter 12 is an optical device for selecting a required radiation wave band, and the light hole 36 is arranged on a light path between the light source 34 and the light receiver 13 and used for enabling the light to be free from being blocked.

In this case, a support 14 may be further disposed on the base 111, the support 14 is rotatably disposed with the supporting plate 15, the supporting plate 15 is substantially a circular flat plate, and a third driving member for driving the supporting plate 15 to rotate is disposed on the support 14, in this embodiment, the third driving member is a motor. The number of the optical filters 12 is at least one, the optical filters 12 are arranged on the supporting plate 15, when the number of the optical filters 12 is multiple, the optical filters 12 are arranged around the rotating axis of the supporting plate 15, and during detection, the third driving member drives the supporting plate 15 to enable the optical filters 12 to be used to be switched to the middle of the light path where the light source 34, the collimating lens 35 and the light receiver are located.

In the using process of the automatic biochemical analyzer, according to the components of a sample to be analyzed and a reagent, the third driving piece drives the supporting plate 15 to rotate together with the optical filter 12, different optical filters 12 are selected, and then biochemical detection of samples to be analyzed with different components is realized.

Referring to fig. 1 to 4, the clamping fixture 5 is provided with a containing hole 16 and a concave hole communicated with the containing hole 16, the containing hole 16 is formed by being recessed from the top surface of the clamping fixture 5, the concave hole penetrates through the inner hole wall of the containing hole 16, an elastic member is arranged in the concave hole, the containing hole 16 is used for containing the container member 6, the elastic member comprises a rolling ball 17 and a spring 18, the rolling ball 17 is contained in the concave hole, and the spring 18 drives the rolling ball 17 to protrude into the containing hole 16 under the action of elastic force so as to abut against the outer surface of the container member 6.

After the container member 6 is loaded into the containing hole 16, the container member 6 is pressed and abutted against the inner hole wall of the containing hole 16 by using the elastic force of the elastic member, and the container member 6 is prevented from falling off the clamping jig 5 in the rotating process of the clamping jig 5. In addition, the rolling ball 17 is abutted against the outer surface of the container part 6, and the rolling ball 17 and the container part 6 are in rolling friction, so that the container part 6 can conveniently enter and exit the clamping jig 5.

The elastic piece also comprises a female threaded column 19 screwed in the concave hole, a spring 18 is positioned between the rolling ball 17 and the threaded column 19, and two ends of the spring 18 respectively abut against the rolling ball 17 and the threaded column 19; according to the needs of the sample to be measured, the user can rotate the threaded column 19 forward and backward, and then adjust the elastic force exerted on the container member 6 by the elastic member, so as to ensure that the container member 6 containing the sample to be measured with various weights can be stably installed in the clamping jig 5.

The containing hole 16 includes a first hole 21 and a second hole 22 communicated with the first hole 21, the aperture of the first hole 21 is larger than that of the second hole 22, the second hole 22 penetrates through the bottom wall of the first hole 21, the concave hole is communicated with the second hole 22, and the bottom wall of the first hole 21 is used for abutting against and stopping the base portion of the container 6.

When the container member 6 is loaded into the first hole 21 and the second hole 22 in the containing hole 16, the bottom wall of the first hole 21 is abutted against and stops the base part of the container member 6, so that the container member 6 is prevented from being excessively loaded into the clamping jig 5, and the installation yield of the container member 6 is improved.

The carrier plate 4 is provided with a heating sheet 23, the heating sheet 23 is accommodated in the carrier plate 4 and is tightly contacted with the carrier plate 4, and the carrier plate 4 and the clamping jig 5 are both made of materials easy to transfer heat; the base 1 is provided with a containing blind groove 33, the containing blind groove 33 is formed by recessing from the top surface of the base 111, and the carrier plate 4 is contained in the containing blind groove 33; the heat generating sheet 23 includes a ring body 24 and a plurality of bar bodies 25 connected to the ring body 24, and the plurality of ring bodies 24 are arranged in a ring array around a central axis of the ring body 24.

The carrier plate 4 includes a base plate 26 and a plurality of extension arms 27 connected with the base plate 26, the base plate 26 rotates and sets up on the base 111, the base plate 26 is roughly discoid, the plurality of extension arms 27 set up around the axis of rotation of base plate 26, preferably, the plurality of extension arms 27 are annular array around the central line axis of base plate 26, the clamping jig 5 rotates and sets up between two adjacent extension arms 27, the ring body 24 is installed and set up on the base plate 26, the bar 25 and the extension arms 27 one-to-one, the ring body 24 sets up around the axis of rotation of base plate 26.

In the using process of the automatic biochemical analyzer, according to the requirement of the reaction of the sample or/and the reagent to be detected in the container member 6, the heating sheet 23 is utilized to heat the sample or/and the reagent to be detected in the container member 6 through the clamping fixture 5, so that the reaction temperature of the sample or/and the reagent to be detected in the container member 6 reaches the required temperature range.

In this embodiment, the substrate 26 and the extension arm 27 are both provided with blind holes 28, the blind holes 28 are formed by recessing from the top surface of the substrate 26 and the top surface of the extension arm 27, the ring body 24 is accommodated in the blind holes 28 of the substrate 26, and the bar body 25 is accommodated in the blind holes 28 of the extension arm 27, so as to increase the contact area between the heat generating sheet 23 and the carrier plate 4, so that the heat generated by the heat generating sheet 23 is directly transferred to the carrier plate 4, and the heat generating sheet 23 is limited by the inner hole wall of the blind holes 28, thereby ensuring that the heat generating sheet 23 is stably arranged on the carrier.

The automatic biochemical analyzer further comprises a code scanning mechanism 29, a pressing mechanism 31 and a heat insulation cover 32, wherein the code scanning mechanism 29 and the pressing mechanism 31 are arranged on the base 111, the code scanning mechanism 29, the mixing mechanism 2, the pressing mechanism 31 and the analyzing mechanism 3 are arranged around the support plate 4, and the code scanning mechanism 29 is provided with a code reader for reading codes on the container members 6 so as to read information of the container members 6; the pressing mechanism 31 is used for pressing the container member 6 to release the pre-embedded reagent in the container member 6, and the mixing mechanism 2 drives the container member 6 to mix upside down through the clamping fixture 5.

In this embodiment, the heat shield 32 is detachably connected to the base 111, and the heat shield 32 is used for covering the opening of the accommodating blind slot 33 so as to enclose the carrier plate 4 and the heat generating sheet 23 in the accommodating blind slot 33. In the use process of the automatic biochemical analyzer, the sample to be measured or/and the reagent in the container 6 are heated by the heat emitted by the heating sheet 23 through the clamping fixture 5, the heating sheet 23, the support plate 4, the clamping fixture 5, the container 6 and the sample to be measured in the container 6 are protected by the heat insulation cover 32, and the diffusion loss of the heat emitted by the heating sheet 23 is reduced.

The above description is only for the preferred embodiment of the present invention, and for those skilled in the art, there are variations on the detailed description and the application scope according to the idea of the present invention, and the content of the description should not be construed as a limitation to the present invention.

Claims

1. An automated biochemical analyzer, comprising: the automatic feeding device comprises a base, a feeding mechanism, a mixing mechanism and an analysis mechanism, wherein the feeding mechanism, the mixing mechanism and the analysis mechanism are arranged on the base; the material mixing mechanism is used for driving the clamping jig to rotate relative to the support plate so as to mix the sample to be detected and/or the reagent in the container part carried by the clamping jig; the analysis mechanism is used for detecting and analyzing the reagent in the container part before/after mixing by the mixing mechanism or the reaction product of the reagent and the sample to be detected.

2. The automated biochemical analyzer according to claim 1, wherein: the material mixing mechanism and the analysis mechanism are arranged around the support plate, the number of the clamping jigs is multiple, the clamping jigs are arranged in an annular array around the rotation axis of the support plate, each clamping jig is used for bearing a container, the rotation axis of the support plate is arranged vertically, and the rotation axis of the clamping jig is arranged horizontally.

3. The automated biochemical analyzer according to claim 1, wherein: the material mixing mechanism comprises a second driving part arranged on the base and a rack connected with the output end of the second driving part, and the clamping jig is provided with a gear used for meshing the rack.

4. The automated biochemical analysis instrument according to claim 3, wherein: the base is provided with a sliding groove, the rack is slidably accommodated in the sliding groove, one end of the rack is connected with the output end of the second driving piece, and the other end of the rack is meshed with the gear through the sliding groove.

5. The automated biochemical analyzer according to claim 1, wherein: the container part is made of a light-transmitting material, the analysis mechanism comprises a light transmitter and a light receiver which are arranged on the base, light emitted by the light transmitter penetrates through a reagent in the container part or a reaction product of the reagent and a sample to be detected and irradiates the light receiver, and the light receiver is used for photoelectric conversion.

6. The automated biochemical analysis instrument according to claim 5, wherein: the light emitter comprises a light source, a collimating lens, an optical filter and a light hole, wherein the light source is a light generator capable of generating a wavelength of 300-800nm, the collimating lens is used for converting scattered light generated by the light source into parallel light, the optical filter is an optical device used for selecting a required radiation waveband, the light hole is positioned on a light path between the light source and the light receiver, and the light hole is used for enabling the light not to be shielded; the base is provided with the support, and the support rotates and is provided with the layer board, and the support is equipped with and is used for driving layer board pivoted third driving piece, and the quantity of light filter is at least one, and the light filter sets up in the layer board, and during the detection, the light filter that third driving piece drive layer board made required use switches to in the middle of the light path at light source, collimating lens, light receiver place.

7. The automated biochemical analyzer according to claim 1, wherein: the clamping jig is provided with a containing hole and a concave hole communicated with the containing hole, an elastic piece is arranged in the concave hole, the containing hole is used for containing the container piece, the elastic piece comprises a rolling ball and a spring, the rolling ball is contained in the concave hole, and the spring drives the rolling ball to protrude into the containing hole under the action of the elastic force to abut against the outer surface of the container piece.

8. The automated biochemical analysis instrument according to claim 7, wherein: the elastic piece also comprises an internal thread column screwed in the concave hole, and two ends of the spring respectively abut against the rolling ball and the thread column; the containing hole comprises a first hole body and a second hole body communicated with the first hole body, the aperture of the first hole body is larger than that of the second hole body, the second hole body penetrates through the bottom wall of the first hole body, the concave hole is communicated with the second hole body, and the bottom wall of the first hole body is used for abutting and stopping the base part of the container piece.

9. The automated biochemical analyzer according to claim 1, wherein: the carrier plate is provided with a heating sheet, the heating sheet is accommodated in the carrier plate and is in close contact with the carrier plate, and the carrier plate and the clamping jig are both made of materials easy to transfer heat; the base is provided with a containing blind groove, and the support plate is contained in the containing blind groove; the support plate includes the base plate and the a plurality of extension arms of being connected with the base plate, and the base plate rotates and sets up in the base, and a plurality of extension arms set up around the axis of rotation of base plate, clamp the tool and rotate and set up between two adjacent extension arms.

10. The automated biochemical analysis instrument according to claim 9, wherein: the automatic biochemical analyzer also comprises a code scanning mechanism, a pressing mechanism and a heat insulation cover, wherein the code scanning mechanism and the pressing mechanism are arranged on the base, the code scanning mechanism, the mixing mechanism, the pressing mechanism and the analysis mechanism are arranged around the support plate, the code scanning mechanism is provided with a code reader for reading codes on the container piece, the pressing mechanism is used for pressing the container piece so as to release pre-embedded reagents in the container piece, and the mixing mechanism drives the container piece to be reversely mixed through the clamping fixture; the heat shield is detachably connected with the base, and when the heat shield is connected with the base, the support plate and the heating sheet and the clamping jig on the support plate are positioned in a relatively closed space.