CN210749654U

CN210749654U - Composite filling device

Info

Publication number: CN210749654U
Application number: CN201920319457.7U
Authority: CN
Inventors: 孙同文; 梁火燕; 丁显飞; 李弘毅; 王诚扬; 朱彦辉; 王栋
Original assignee: First Affiliated Hospital of Zhengzhou University
Current assignee: First Affiliated Hospital of Zhengzhou University
Priority date: 2018-11-21
Filing date: 2019-03-14
Publication date: 2020-06-16
Anticipated expiration: 2029-03-14

Abstract

The utility model discloses a composite perfusion device, belonging to the field of medical apparatus, comprising a transfusion bag, a transfusion tube connected with the transfusion bag, a needle head arranged at the end part of the transfusion tube, a transfusion pressurizing bag and a frog heart clip, wherein the annular air bag of the transfusion pressurizing bag is encircled on the outer ring of the transfusion bag; the frog heart clamp comprises two clamping rod parts and a spiral ring part connected between the two clamping rod parts, the two ends of the spiral ring part are fixedly connected with the two clamping rod parts respectively, the clamping rod parts are transversely arranged, the spiral ring part is vertically arranged, the needle head comprises a needle head base tube and a puncture needle, the end part of a transfusion tube is inserted into the needle head base tube of the needle head, and the needle head base tube can penetrate through the spiral ring part of the frog heart clamp. The utility model relates to a compound perfusion device convenient to one-man operation.

Description

Composite filling device

Technical Field

The utility model belongs to the field of medical equipment, especially, relate to a compound perfusion device.

Background

Perfusion is an important technology in animal experiments, and aims to better control the liquid amount of physiological saline injected through a systemic circulation way according to experimental requirements so as to remove blood in tissues and facilitate subsequent histopathological analysis.

The commonly used perfusion device at present comprises a fixing plate, an injection needle and an infusion apparatus, wherein the left ventricle puncture channel is used for perfusion after an anesthetized experimental animal is fixed, the commonly used perfusion device is an injector with a large capacity (such as 50ml) or a clinical infusion support, the large-capacity injector has high flow rate and good effect when in use, but needs at least two persons to operate together, wastes labor and time, needs to continuously replace the injector, and is easy to cause the deviation of the needle head or penetrate the heart once the needle head is separated from the heart and punctures the heart to influence the perfusion effect; and the pressure of the infusion support is too low, so that the air needs to be continuously injected through the needle to improve the pressure, the infusion effect is poor even if a large-caliber needle head is adopted, and the liquid is not convenient to infuse under stable pressure.

SUMMERY OF THE UTILITY MODEL

The utility model aims at providing a compound perfusion device who is applicable to rat heart perfusion convenient to one-man operation.

In order to achieve the above purpose, the utility model adopts the following technical scheme: a composite perfusion device comprises a transfusion bag, a transfusion tube connected with the transfusion bag, a needle head arranged at the end part of the transfusion tube, a transfusion pressurization bag and a frog heart clamp, wherein an annular air bag of the transfusion pressurization bag is surrounded on the outer ring of the transfusion bag; the frog heart clamp comprises two clamping rod parts and a spiral ring part connected between the two clamping rod parts, the two ends of the spiral ring part are fixedly connected with the two clamping rod parts respectively, the clamping rod parts are transversely arranged, the spiral ring part is vertically arranged, the needle head comprises a needle head base tube and a puncture needle, the end part of a transfusion tube is inserted into the needle head base tube of the needle head, and the needle head base tube can penetrate through the spiral ring part of the frog heart clamp.

The inner diameter of the spiral ring part of the frog heart clip is larger than the outer diameter of the needle head base tube of the needle head.

When the puncture needle is inserted into the animal ventricle and the frog heart clamp clamps the animal myocardium, the spiral ring part surrounds the outer ring of the needle head base tube, and the needle head base tube is lapped on the upper side of the bottom end inner edge of the spiral ring part of the frog heart clamp.

The end part of the infusion tube is tightly matched with the base tube of the needle head.

The needle is a 50ml syringe needle.

A compound perfusion device, when filling the experiment to the experimental animal, the animal is pricked into to the pjncture needle front end, the syringe needle parent tube is supported by the helicoid part, consequently can prevent syringe needle tail end (syringe needle parent tube) from drooping, press the ball through manual extrusion infusion pressurization bag, inflate the pressurization for the annular gasbag of infusion pressurization bag, the annular gasbag inflation, volume increase and extrusion infusion bag, liquid medicine in the infusion bag receives the extrusion and flows to the syringe needle from the infusion pipe, inject the animal internally by the syringe needle, manual for annular gasbag and infusion bag pressurization be convenient for experimental operation. The whole process can be operated by one person.

Drawings

Fig. 1 is a schematic structural diagram of the present invention;

FIG. 2 is a schematic view of the structure of an infusion pressurizing bag and an infusion bag;

FIG. 3 is a perspective view of the frog heart clip gripping the myocardium and the needle penetrating the myocardium;

FIG. 4 is a schematic view of the frog heart clip in position to clamp the myocardium and the needle penetrating the myocardium;

FIG. 5 is a cross-sectional view of the needle base tube riding inside the bottom end of the coil section along the upper side;

FIG. 6 is a schematic view of the needle base tube riding on the upper side of the bottom end inside the coil portion;

in the figure: the infusion bag comprises an infusion bag 1, a liquid outlet 2, an infusion tube 3, an annular air bag 4, a spiral ring part 5, an air tube 6, a needle 7, a clamping rod part 8, a frog heart clamp 9, a needle base tube 10, a puncture needle 11, an infusion pressurizing bag 12, a pressing ball 13, an air valve 14 and a cardiac muscle 15.

Detailed Description

The compound perfusion device shown in fig. 1-6 comprises an infusion bag 1, an infusion tube 3 connected with the infusion bag 1, a needle 7 arranged at the end of the infusion tube 3, an infusion pressurizing bag 12 and a frog heart clamp 9.

Infusion bag 1's material is plastics, syringe needle 7 includes syringe needle parent tube 10 and pjncture needle 11, and the tail end of pjncture needle 11 is fixed on syringe needle parent tube 10, syringe needle parent tube 10 and pjncture needle 11 intercommunication, and in this embodiment, the rear end of pjncture needle 11 is fixed in syringe needle parent tube 10 front end, and syringe needle 7 is the current product of purchasing on the market, so do not describe in detail.

Infusion bag 1 passes through transfer line 3 and connects syringe needle 7, specifically, infusion bag 1 sets up

liquid outlet

2, and 3 one ends of transfer line insert in infusion bag 1 liquid outlet 2, the other end insert syringe needle parent tube 10, be the tight fit between 3 other ends of transfer line and the syringe needle parent tube 10, further, the outer wall of 3 one ends of transfer line is tight fit, the outer wall of the other end and 10 internal face tight fits of syringe needle parent tube 10 with the internal face of infusion bag 1 liquid outlet 2, and infusion bag 1 communicates syringe needle 7 through transfer line 3.

The infusion pressurization bag 12 comprises a handheld pressing ball 13 and an annular air bag 4 connected with the pressing ball 13 through an air pipe 6, the air pipe 6 is provided with an air valve 14, the pressing ball 13 is an elastic air bag, when the pressing ball 13 is communicated with the annular air bag through the air valve, the pressing ball 13 is pinched flat by a hand, air in the pressing ball 13 can be extruded to the annular air bag 4 through the air pipe 6 to inflate the annular air bag, the pressing ball 13 is loosened by the hand, and the pressing ball 13 is restored to the original shape. The annular air bag 4 of the infusion pressurization bag 12 is surrounded on the outer ring of the infusion bag and is used for pressurizing the infusion bag, the pressing ball 13 of the infusion pressurization bag 12 is manually pressed to inflate and pressurize the annular air bag 4 of the infusion pressurization bag 12, the annular air bag 4 expands, the volume is increased, the infusion bag is pressed, liquid medicine in the infusion bag is pressed, flows to a needle from the infusion tube, and is injected into an animal body through the needle. The infusion pressurizing bag 12 is a commercially available product, and therefore, will not be described in detail.

The frog heart clamp 9 comprises two clamping rod parts 8 and a spiral ring part 5 connected between the two clamping rod parts 8, the two ends of the spiral ring part 5 are fixedly connected with the end parts of the two clamping rod parts 8 respectively, the spiral ring part 5 and the two clamping rod parts 8 are of an integrated structure, the clamping rod parts 8 are bent, the clamping rod parts 8 are transversely arranged, the spiral ring part 5 is vertically arranged, the spiral ring part 5 is spiral, when the clamping rod parts 8 are arranged on a horizontal desktop, the clamping rod parts 8 are integrally and transversely arranged front and back, the two clamping rod parts 8 are oppositely arranged left and right, at the moment, the spiral ring part 5 is vertically arranged, the central line of the spiral ring part 5 extends front and back transversely, and the two bottom ends of the spiral ring part 5 are fixedly connected with the rear ends of the two clamping rod parts 8 respectively in an integrated manner; the frog heart clip 9 is an improvement on the existing frog heart clip 9, and can be obtained by rotating the spiral ring part 5 of the existing frog heart clip 9 in the clockwise direction or the anticlockwise direction by about 90 degrees to the side far away from the clip rod part 8.

The internal diameter of the helicoid part that the frog heart pressed from both sides is greater than the biggest external diameter of the syringe needle parent tube of syringe needle all the time for no matter whether the frog heart pressed from both sides the centre gripping object, the helicoid part that the frog heart pressed from both sides all can alternate in the syringe needle parent tube, and the helicoid part cover that the frog heart pressed from both sides has the clearance in the time of syringe needle parent tube outer lane between syringe needle parent tube and the helicoid part, so that the syringe needle parent tube adjusts the direction slightly.

When the puncture needle is inserted into the ventricle of an animal and the frog heart clip clamps the myocardium 15 of the animal, the needle head base tube penetrates through the spiral ring part of the frog heart clip, at the moment, the middle rear part or the rear end of the needle head base tube is lapped on the upper side of the inner edge of the bottom end of the spiral ring part of the frog heart clip, the spiral ring part surrounds the outer ring of the middle rear part of the needle head base tube or the outer ring of the rear end of the needle head base tube, the front part of the needle head base tube extends forwards out of the spiral ring part, and the spiral ring.

Taking heart perfusion of experimental animals as an example: the experimental animal selects a rat, a syringe needle with the needle head of 50ml is selected, a frog heart clip purchased from the market is transformed into the frog heart clip of the utility model, in the embodiment, the frog heart clip purchased from the market selects a frog heart clip with the length of 2.2cm (the frog heart clip purchased from the market can be purchased from Taobao Borui Dai laboratory mall, the website is https:// item.taobao.com/item.htm? 536897798834, and the B money in the webpage is 2.2cm), the spiral ring part of the existing frog heart clip is rotated around the joint of the spiral ring part and the clamping rod part, so that the spiral ring part is approximately vertical to the plane of the two clamping rod parts; a Smith blood transfusion and infusion pressurizing bag 1000ml clear-cuff MX4710 silica gel air bag is selected for transfusion and pressurization, a normal saline infusion bag is placed into an annular air bag 4, the annular air bag 4 is wrapped on the outer ring of the infusion bag, the infusion bag and the annular air bag 4 are inverted, after the infusion bag is connected with an infusion tube, the thoracic cavity of a rat is opened, the heart is exposed, a needle base tube passes through a spiral ring part, the spiral ring part is encircled on the outer ring of the middle rear part of the needle base tube or the outer ring of the rear end of the needle base tube, the two clamping rod parts are tightly held by one hand and pushed oppositely to ensure that the front ends of the two clamping rod parts are opened left and right to form a clamping opening, the other hand grasps the front part of the needle base tube and pierces a puncture needle into a left frog tip, a frog core clamp is loosened to clamp the myocardium 15 near the puncture position of the needle, the frog tip is fixed on the myocardium 15, and because the front end of the puncture needle is pierced into the left frog, the needle is kept in a state of being transversely placed in the front and back, then the air valve 14 of the infusion pressurizing bag 12 is opened, the pressing ball 13 is continuously pressed to inflate and pressurize the annular air bag 4, the annular air bag 4 presses the infusion bag in the annular air bag 4 and pressurizes the infusion bag, so that liquid in the infusion bag 1 flows into the infusion tube 3 from the liquid outlet 2 of the infusion bag 1 and enters the needle 7 from the infusion tube 3, namely firstly enters the needle base tube 10 and then is injected into a rat body from the puncture needle 11, the air valve 14 is closed after the required infusion speed is reached, and finally, the infusion is completed. The left apex of the heart and the viscera of the rat with different perfusion speeds can show different performances, for example, the perfusion speed is too high, the flow speed of blood flowing out through the inferior vena cava is high and much, the color of the blood is changed from bright red to light red rapidly, the blood color of other viscera (especially liver) disappears rapidly, the color of the viscera with too low perfusion speed is changed slowly, the color of the visible viscera section is not changed (caused by blood coagulation formation), whether the perfusion speed is proper or not is judged according to the color change of the viscera and the blood flowing out speed of the inferior vena cava, if the speed is too low, the pressure ball 13 is pinched by hands for multiple times to pressurize, the perfusion speed is increased, otherwise, the air valve 14 is adjusted, the air valve 14 is rotated to a pressure relief state, partial air in the annular air. The utility model discloses not only be in the above-mentioned form, can choose for use syringe needle and the frog heart of different models, parameter size of different parameters size as required to press from both sides, infusion pressurization bag etc. to different experimental animals.

A compound perfusion device, easy and simple to handle, whole process, one-man operation can.

Claims

1. A composite perfusion device, comprising: the transfusion bag comprises a transfusion bag (1), a transfusion tube (3) connected with the transfusion bag (1), a needle (7) arranged at the end part of the transfusion tube (3), a transfusion pressurization bag (12) and a frog heart clamp (9), wherein an annular air bag (4) of the transfusion pressurization bag (12) is surrounded on the outer ring of the transfusion bag (1); frog heart presss from both sides (9) including two clamping bar parts (8) and spiral circle part (5) of connection between two clamping bar parts (8), two clamping bar parts (8) of fixed connection are distinguished at the both ends of spiral circle part (5), and clamping bar part (8) transversely set up, the vertical setting of spiral circle part (5), syringe needle (7) are including syringe needle parent tube (10) and pjncture needle (11), and during syringe needle parent tube (10) of syringe needle (7) were inserted to the tip of transfer line (3), spiral circle part (5) that frog heart pressed from both sides (9) can be alternate in syringe needle parent tube (10).

2. A composite infusion device as claimed in claim 1, wherein: the inner diameter of the spiral ring part (5) of the frog heart clip (9) is larger than the outer diameter of the needle base tube (10) of the needle (7).

3. A composite infusion device as claimed in claim 1, wherein: when the puncture needle (11) is inserted into the ventricle of the animal and the frog heart clip (9) clips the cardiac muscle of the animal, the spiral ring part (5) surrounds the outer ring of the needle base tube (10), and the needle base tube (10) is lapped on the upper side of the bottom end inner edge of the spiral ring part (5) of the frog heart clip (9).

4. A composite infusion device as claimed in claim 1, wherein: the end part of the infusion tube (3) is tightly matched with the needle head base tube (10).

5. A compound infusion device as claimed in claim 4, wherein: the needle (7) is a 50ml syringe needle.