CN210656890U - Nucleic acid purification kit - Google Patents
Nucleic acid purification kit Download PDFInfo
- Publication number
- CN210656890U CN210656890U CN201921369887.6U CN201921369887U CN210656890U CN 210656890 U CN210656890 U CN 210656890U CN 201921369887 U CN201921369887 U CN 201921369887U CN 210656890 U CN210656890 U CN 210656890U
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- wall
- rod
- fixedly connected
- nucleic acid
- acid purification
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- 238000001821 nucleic acid purification Methods 0.000 title claims abstract description 30
- 230000007246 mechanism Effects 0.000 claims abstract description 13
- 230000006835 compression Effects 0.000 claims description 7
- 238000007906 compression Methods 0.000 claims description 7
- 239000003153 chemical reaction reagent Substances 0.000 abstract description 15
- 210000002421 cell wall Anatomy 0.000 abstract description 5
- 230000006872 improvement Effects 0.000 abstract description 3
- 230000000694 effects Effects 0.000 description 9
- 238000000034 method Methods 0.000 description 9
- 238000000605 extraction Methods 0.000 description 4
- 150000007523 nucleic acids Chemical class 0.000 description 4
- 102000039446 nucleic acids Human genes 0.000 description 4
- 108020004707 nucleic acids Proteins 0.000 description 4
- 239000007787 solid Substances 0.000 description 4
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 3
- 239000011324 bead Substances 0.000 description 3
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 description 2
- 238000001514 detection method Methods 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 230000007613 environmental effect Effects 0.000 description 2
- 239000011148 porous material Substances 0.000 description 2
- 208000035473 Communicable disease Diseases 0.000 description 1
- 238000007400 DNA extraction Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 239000000428 dust Substances 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 230000004907 flux Effects 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 239000011435 rock Substances 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
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- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The utility model relates to the technical field of nucleic acid purification, and discloses a nucleic acid purification kit, which comprises a box body, wherein the upper end of the box body is connected with a box cover through a fixing mechanism, and the side wall of the lower side of the box cover is connected with a limiting mechanism; the fixed establishment includes two fixed cardboard of fixed connection at lid downside lateral wall, two fixed cardboard is located the box body, two the sliding tray has all been seted up to the lateral wall that fixed cardboard is close to box body one side, the removal kelly has been cup jointed in the sliding tray internalization, the pole wall of removal kelly and the cell wall sliding connection of sliding tray, the same reset spring of fixedly connected with between the tank bottom of removal kelly and sliding tray. The utility model discloses can be quick carry out steady fixed to the lid, improve the security that the kit used, still effectual improvement the stability that reagent was placed.
Description
Technical Field
The utility model relates to a nucleic acid purification technical field especially relates to nucleic acid purification kit.
Background
The nucleic acid purification kit is a nucleic acid purification kit for testing by a magnetic bead method, and the magnetic bead method is used for nucleic acid extraction, has incomparable advantages compared with the traditional DNA extraction method, and is mainly embodied in that: the automatic nucleic acid extractor can realize automatic and large-batch operation, can realize the treatment of 96 samples by using the extraction time of one sample, meets the operation requirement of biological high flux, can quickly and timely deal with infectious diseases during outbreak, and has the characteristic that the traditional method is extremely good at dust; the operation is simple, the time consumption is short, the whole extraction process only comprises four steps, and most of the extraction process can be completed within 36-40 minutes; the method is safe and nontoxic, toxic reagents such as benzene and chloroform in the traditional method are not used, the harm to experiment operators is reduced to the minimum, and the method completely conforms to the modern environmental protection concept; the specific combination of the magnetic beads and the nucleic acid ensures that the extracted nucleic acid has high purity and high concentration. The nucleic acid purification kit can be applied to various fields of clinical disease diagnosis, blood transfusion safety, forensic medicine identification, environmental microorganism detection, food safety detection, molecular biology research and the like
Current nucleic acid purification kit is fixed because the lid of kit is through simple buckle when using, leads to the lid fixed comparatively insecure, and opens comparatively inconveniently, and the inside reagent of current nucleic acid purification kit lacks spacing fixed, leads to the inside reagent of nucleic acid purification kit to rock easily when the transportation, influences the security of reagent.
SUMMERY OF THE UTILITY MODEL
The utility model aims at solving the problem that the lid of the nucleic acid purification kit is fixed and is comparatively unstable and reagent places unstably among the prior art, and the nucleic acid purification kit that provides.
In order to achieve the above purpose, the utility model adopts the following technical scheme:
the nucleic acid purification kit comprises a kit body, wherein the upper end of the kit body is connected with a kit cover through a fixing mechanism, and the side wall of the lower side of the kit cover is connected with a limiting mechanism;
fixed establishment includes two fixed cardboard of fixed connection at lid downside lateral wall, two fixed cardboard is located the box body, two the sliding tray has all been seted up to the lateral wall that fixed cardboard is close to box body one side, the activity has cup jointed the removal kelly in the sliding tray, the pole wall of removal kelly and the cell wall sliding connection of sliding tray, the same reset spring of fixedly connected with between the tank bottom of removal kelly and sliding tray, the sliding hole corresponding with the removal kelly has all been seted up to the lateral wall of the box body left and right sides, the ejector pin has been cup jointed in the activity of sliding hole, the pole wall of ejector pin and the pore wall sliding connection of sliding hole, the sliding hole is stretched out to the one end of ejector pin, two locating pieces of lateral wall fixedly connected with of lid downside, two constant head tanks corresponding with the locating piece are seted up to the.
Preferably, stop gear includes two fixed connection at the solid fixed cylinder of lid downside lateral wall, two equal activity has cup jointed the carriage release lever in the solid fixed cylinder, the same root pressure spring of fixedly connected with between the bobbin base of carriage release lever and solid fixed cylinder, solid fixed cylinder is all stretched out to the lower extreme of carriage release lever, two the same clamp plate of fixedly connected with between the carriage release lever.
Preferably, the standing groove has been seted up to the lateral wall of lid upside, two mounting panels of the tank bottom symmetry fixedly connected with of standing groove, two U type groove has all been seted up to the lateral wall of mounting panel upside, the same root fixed axle of fixedly connected with between the cell wall of the relative one side in U type groove, two the axle wall movable sleeve of fixed axle is equipped with same U type pull rod, two rotation holes have been seted up to the pole wall symmetry of U type pull rod, the fixed axle runs through U type pull rod through rotating the hole.
Preferably, the four corners of the lower surface of the box body are fixedly connected with supporting columns.
Preferably, the four corners of the upper surface of the box cover are provided with fixing grooves.
Preferably, the groove wall of the opposite side of the sliding groove is fixedly connected with a sliding block, and the rod wall of the movable clamping rod is symmetrically provided with two sliding grooves matched with the sliding block.
Preferably, the rod wall of the ejector rod is symmetrically and fixedly connected with two limiting slide blocks, and the hole wall of the sliding hole is symmetrically provided with two limiting sliding grooves matched with the limiting slide blocks.
Preferably, the rod wall of the moving rod is symmetrically and fixedly connected with two limiting clamping blocks, and the inner wall of the fixed cylinder is symmetrically provided with two limiting clamping grooves matched with the limiting clamping blocks.
Preferably, the rod wall of the U-shaped pull rod is fixedly sleeved with an anti-skid sleeve.
Preferably, the ejector pin is located the one end fixedly connected with limiting plate outside the sliding hole, the same compression spring of fixedly connected with between limiting plate and the box body, compression spring movable sleeve locates outside the ejector pin.
Compared with the prior art, the utility model provides a nucleic acid purification kit possesses following beneficial effect:
1. this nucleic acid purification kit, through the fixed establishment who sets up, during the use, press the ejector pin, the ejector pin drives and removes the removal kelly, make the removal kelly withdraw from the sliding hole, remove the removal kelly spacing to fixed cardboard, the lid can be taken off to the pulling lid, when installing the lid, press two removal kellies, insert the locating piece in the constant head tank, loosen the removal kelly, press the lid, make the removal kelly aim at the sliding hole, under the effect of reset spring self resilience power, reset spring drives the removal kelly and removes, make the removal kelly card go into the sliding hole, the removal kelly carries out spacing fixed to fixed cardboard, thereby accomplish the firm fixed to the lid, and easy operation is convenient, can be quick carry out steadily fixed to the lid, the security that the improvement kit used.
2. This nucleic acid purification kit, through the stop gear who sets up, during the use, under the effect of pressure spring self resilience force, the pressure spring drives the carriage release lever downstream, and two carriage release levers drive the clamp plate downstream, and the clamp plate carries on spacingly to the reagent in the reagent box, prevents that reagent from rocking at the in-process of transportation, the effectual stability that places that has improved reagent.
The part that does not relate to in the device all is the same with prior art or can adopt prior art to realize, the utility model discloses can be quick carry out steadily fixedly to the lid, improve the security that the kit used, still effectual improvement the stability that reagent was placed.
Drawings
FIG. 1 is a schematic structural diagram of a nucleic acid purification kit according to the present invention;
FIG. 2 is a schematic structural view of portion A of FIG. 1;
FIG. 3 is a schematic structural diagram of portion B of FIG. 1;
fig. 4 is a schematic structural view of a portion C in fig. 1.
In the figure: the automatic locking device comprises a box body 1, a fixing mechanism 2, a fixing clamping plate 21, a sliding groove 22, a movable clamping rod 23, a reset spring 24, a sliding hole 25, a push rod 26, a positioning block 27, a positioning groove 28, a box cover 3, a limiting mechanism 4, a fixing barrel 41, a movable rod 42, a pressure spring 43, a pressure plate 44, a placing groove 5, a mounting plate 6, a U-shaped groove 7, a fixing shaft 8, a pull rod 9U-shaped, a rotating hole 10, a supporting column 11, a fixing groove 12, an anti-skidding sleeve 13, a limiting plate 14 and a compression spring 15.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments.
In the description of the present invention, it is to be understood that the terms "upper", "lower", "front", "rear", "left", "right", "top", "bottom", "inner", "outer", and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and simplicity of description, and do not indicate or imply that the device or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore, should not be construed as limiting the present invention.
Referring to fig. 1-4, the nucleic acid purification kit comprises a box body 1, wherein the upper end of the box body 1 is connected with a box cover 3 through a fixing mechanism 2, and the side wall of the lower side of the box cover 3 is connected with a limiting mechanism 4;
fixed establishment 2 includes two fixed cardboard 21 of fixed connection at 3 downside lateral walls of lid, two fixed cardboard 21 are located box body 1, sliding tray 22 has all been seted up to the lateral wall that two fixed cardboard 21 are close to box body 1 one side, movable clamping rod 23 has been cup jointed in the activity of sliding tray 22, the pole wall of movable clamping rod 23 and the cell wall sliding connection of sliding tray 22, the same reset spring 24 of fixedly connected with between the tank bottom of movable clamping rod 23 and sliding tray 22, sliding hole 25 corresponding with movable clamping rod 23 has all been seted up to the lateral wall of the 1 left and right sides of box body, ejector pin 26 has been cup jointed in the activity of sliding hole 25, the pole wall of ejector pin 26 and the pore wall sliding connection of sliding hole 25, sliding hole 25 is stretched out to the one end of ejector pin 26, two locating pieces 27 of lateral wall fixedly connected with of lid 3 downside, two locating slots 28 corresponding with locating piece 27 have been.
The limiting mechanism 4 comprises two fixed cylinders 41 fixedly connected to the side wall of the lower side of the box cover 3, moving rods 42 are movably sleeved in the two fixed cylinders 41, the same pressure spring 43 is fixedly connected between the moving rods 42 and the bottom of the fixed cylinders 41, the lower ends of the moving rods 42 extend out of the fixed cylinders 41, and the same pressure plate 44 is fixedly connected between the two moving rods 42.
Standing groove 5 has been seted up to the lateral wall of 3 upsides of lid, two mounting panels 6 of the tank bottom symmetry fixedly connected with of standing groove 5, U type groove 7 has all been seted up to the lateral wall of two mounting panels 6 upsides, the same root fixed axle 8 of fixedly connected with between the cell wall of the relative one side in U type groove 7, the axle wall movable sleeve of two fixed axles 8 is equipped with same U type pull rod 9, two rotation holes 10 have been seted up to the pole wall symmetry of U type pull rod 9, fixed axle 8 runs through U type pull rod 9 through rotating hole 10.
The four corners of the lower surface of the box body 1 are fixedly connected with supporting columns 11.
The four corners of the upper surface of the box cover 3 are provided with fixing grooves 12.
The wall of the opposite side of the sliding groove 22 is fixedly connected with a sliding block, and the rod wall of the movable clamping rod 23 is symmetrically provided with two sliding grooves matched with the sliding block.
The rod wall of the ejector rod 26 is symmetrically and fixedly connected with two limiting slide blocks, and the hole wall of the sliding hole 25 is symmetrically provided with two limiting sliding grooves matched with the limiting slide blocks.
Two limiting clamping blocks are symmetrically and fixedly connected to the rod wall of the moving rod 42, and two limiting clamping grooves matched with the limiting clamping blocks are symmetrically formed in the inner wall of the fixed cylinder 41.
The rod wall of the U-shaped pull rod 9 is fixedly sleeved with an anti-skid sleeve 13.
One end of the ejector rod 26, which is positioned outside the sliding hole 25, is fixedly connected with a limiting plate 14, the same compression spring 15 is fixedly connected between the limiting plate 14 and the box body 1, and the compression spring 15 is movably sleeved outside the ejector rod 26.
In the utility model, in using, press ejector pin 26, ejector pin 26 drives removal kelly 23 and moves, make removal kelly 23 withdraw from sliding hole 25, remove removal kelly 23 spacing to fixed cardboard 21, pulling lid 3 can take off lid 3, when installing lid 3, press two removal kellies 23, insert locating piece 27 in locating slot 28, loosen removal kelly 23, press lid 3, make removal kelly 23 aim at sliding hole 25, under the effect of reset spring 24 self resilience force, reset spring 24 drives removal kelly 23 and moves, make removal kelly 23 block into sliding hole 25, removal kelly 23 carries out spacing fixed to fixed cardboard 21, thereby accomplish the firm fixed to lid 3, and easy and convenient operation, can be quick carry out the stable fixed to lid 3, improve the security that the kit used; during the use, under the effect of pressure spring 43 self resilience force, pressure spring 43 drives movable rod 42 downstream, and two movable rods 42 drive clamp plate 44 downstream, and clamp plate 44 carries on spacingly to the reagent in the reagent box, prevents that reagent from rocking at the in-process of transportation, the effectual stability that places that has improved reagent.
The above, only be the concrete implementation of the preferred embodiment of the present invention, but the protection scope of the present invention is not limited thereto, and any person skilled in the art is in the technical scope of the present invention, according to the technical solution of the present invention and the utility model, the concept of which is equivalent to replace or change, should be covered within the protection scope of the present invention.
Claims (10)
1. The nucleic acid purification kit comprises a kit body (1) and is characterized in that the upper end of the kit body (1) is connected with a kit cover (3) through a fixing mechanism (2), and the side wall of the lower side of the kit cover (3) is connected with a limiting mechanism (4);
the fixing mechanism (2) comprises two fixing clamping plates (21) fixedly connected with the side wall of the lower side of the box cover (3), the two fixing clamping plates (21) are positioned in the box body (1), the side walls of the two fixing clamping plates (21) close to one side of the box body (1) are respectively provided with a sliding groove (22), a moving clamping rod (23) is movably sleeved in the sliding groove (22), the rod wall of the moving clamping rod (23) is in sliding connection with the groove wall of the sliding groove (22), a same reset spring (24) is fixedly connected between the moving clamping rod (23) and the groove bottom of the sliding groove (22), the side walls of the left side and the right side of the box body (1) are respectively provided with a sliding hole (25) corresponding to the moving clamping rod (23), an ejector rod (26) is movably sleeved in the sliding hole (25), the rod wall of the ejector rod (26) is in sliding connection with the hole wall of the sliding hole (, one end of the ejector rod (26) extends out of the sliding hole (25), the side wall of the lower side of the box cover (3) is fixedly connected with two positioning blocks (27), and the side wall of the upper side of the box body (1) is provided with two positioning grooves (28) corresponding to the positioning blocks (27).
2. The nucleic acid purification kit according to claim 1, wherein the limiting mechanism (4) comprises two fixed cylinders (41) fixedly connected to the lower side wall of the box cover (3), moving rods (42) are movably sleeved in the two fixed cylinders (41), the same pressure spring (43) is fixedly connected between the moving rods (42) and the bottom of the fixed cylinder (41), the lower ends of the moving rods (42) extend out of the fixed cylinder (41), and the same pressure plate (44) is fixedly connected between the two moving rods (42).
3. The nucleic acid purification kit according to claim 1, wherein the side wall of the upper side of the box cover (3) is provided with a placing groove (5), the bottom of the placing groove (5) is symmetrically and fixedly connected with two mounting plates (6), the side walls of the upper sides of the two mounting plates (6) are both provided with U-shaped grooves (7), the same fixing shaft (8) is fixedly connected between the groove walls of the opposite sides of the U-shaped grooves (7), the shaft wall of the two fixing shafts (8) is movably sleeved with the same U-shaped pull rod (9), the rod wall of the U-shaped pull rod (9) is symmetrically provided with two rotating holes (10), and the fixing shaft (8) penetrates through the U-shaped pull rod (9) through the rotating holes (10).
4. The nucleic acid purification kit according to claim 1, wherein support columns (11) are fixedly connected to four corners of the lower surface of the box body (1).
5. The nucleic acid purification kit according to claim 1, wherein the four corners of the upper surface of the box cover (3) are provided with fixing grooves (12).
6. The nucleic acid purification kit according to claim 1, wherein the wall of the groove opposite to the slide groove (22) is fixedly connected with a slide block, and the rod wall of the movable clamping rod (23) is symmetrically provided with two slide grooves matched with the slide block.
7. The nucleic acid purification kit according to claim 1, wherein the rod wall of the ejector rod (26) is symmetrically and fixedly connected with two limiting sliding blocks, and the wall of the sliding hole (25) is symmetrically provided with two limiting sliding grooves matched with the limiting sliding blocks.
8. The nucleic acid purification kit according to claim 2, wherein the rod wall of the movable rod (42) is symmetrically and fixedly connected with two limiting clamping blocks, and the inner wall of the fixed cylinder (41) is symmetrically provided with two limiting clamping grooves matched with the limiting clamping blocks.
9. The nucleic acid purification kit according to claim 3, wherein the rod wall of the U-shaped pull rod (9) is fixedly sleeved with an anti-slip sleeve (13).
10. The nucleic acid purification kit according to claim 1, wherein one end of the ejector rod (26) located outside the sliding hole (25) is fixedly connected with a limiting plate (14), the same compression spring (15) is fixedly connected between the limiting plate (14) and the box body (1), and the compression spring (15) is movably sleeved outside the ejector rod (26).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201921369887.6U CN210656890U (en) | 2019-08-22 | 2019-08-22 | Nucleic acid purification kit |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201921369887.6U CN210656890U (en) | 2019-08-22 | 2019-08-22 | Nucleic acid purification kit |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN210656890U true CN210656890U (en) | 2020-06-02 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201921369887.6U Active CN210656890U (en) | 2019-08-22 | 2019-08-22 | Nucleic acid purification kit |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN210656890U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113044366A (en) * | 2021-03-26 | 2021-06-29 | 河南理工大学 | Mitochondrial membrane potential detection kit |
-
2019
- 2019-08-22 CN CN201921369887.6U patent/CN210656890U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113044366A (en) * | 2021-03-26 | 2021-06-29 | 河南理工大学 | Mitochondrial membrane potential detection kit |
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