CN208791661U - A kind of paramagnetic particle method nucleic acid magnetic frame - Google Patents
A kind of paramagnetic particle method nucleic acid magnetic frame Download PDFInfo
- Publication number
- CN208791661U CN208791661U CN201821499948.6U CN201821499948U CN208791661U CN 208791661 U CN208791661 U CN 208791661U CN 201821499948 U CN201821499948 U CN 201821499948U CN 208791661 U CN208791661 U CN 208791661U
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- China
- Prior art keywords
- nucleic acid
- test tube
- connecting rod
- particle method
- paramagnetic particle
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Abstract
The utility model discloses a kind of paramagnetic particle method nucleic acid magnetic frame, it include pedestal, rack for test tube is installed above the pedestal, the rack for test tube is respectively support plate and placement plate, the placement plate setting is square on the supporting plate, accommodating chamber is provided in the placement plate surface, the receiving cavity wall two sides are provided with fixed block, first connecting rod is provided with below the fixed block, the first connecting rod underside is connected with the second connecting rod, idler wheel is installed below second connecting rod, the receiving cavity wall two sides, which are located at below fixed block, is provided with receiving pipe, spring is provided in the receiving pipe, wherein one end is provided with jacking block to the spring；The paramagnetic particle method nucleic acid magnetic frame can also meet various different sample nucleic acids under the premise of not reducing nucleic acid extraction effect and extract demand.
Description
Technical field
The utility model relates to a kind of magnetic frames, and especially one kind is not under the premise of reducing nucleic acid extraction effect, moreover it is possible to
Enough meet the nucleic acid magnetic frame that various different sample nucleic acids extract demand.
Background technique
It has obtained widely answering in genetic engineering field with the development of science and technology, separating DNA using paramagnetic particle method and extracting
With.Magnetic bead is added in the DNA sample for needing to separate and extract, it is when not applying external magnetic field, reagent and sample is sufficiently mixed
It closes, makes the nucleic acid molecules in magnetic bead absorption sample, then polymerize magnetic bead by applying external magnetic field, by magnetic bead and sample solution
Then separation washs magnetic bead to obtain the nucleic acid molecules for needing to extract.Above-mentioned operation is generally completed by magnetic frame, existing
Magnetic frame Reagent Tube socket size be it is fixed, when needing the nucleic acid extraction of different samples, reagent pipe size requires just each
Different, the socket of single size is not obviously able to satisfy the nucleic acid extraction demand of various different samples, even and if by the ruler of socket
It is very little to become larger to meet various sizes of Reagent Tube, but it is easy to cause Reagent Tube vertical since socket becomes larger, thus can
Reduce nucleic acid extraction effect.
Utility model content
In view of this, the utility model aim is to provide one kind can also expire under the premise of not reducing nucleic acid extraction effect
The various different sample nucleic acids of foot extract the paramagnetic particle method nucleic acid magnetic frame of demand.
In order to solve the above-mentioned technical problem, the technical solution of the utility model is: a kind of paramagnetic particle method nucleic acid magnetic frame, including
There is pedestal, rack for test tube is installed above the pedestal, the rack for test tube is respectively support plate and placement plate, the placement plate setting
It is square on the supporting plate, it is provided with accommodating chamber in the placement plate surface, the receiving cavity wall two sides are provided with fixed block, described
First connecting rod is provided with below fixed block, the first connecting rod underside is connected with the second connecting rod, and described second connects
Idler wheel is installed, the receiving cavity wall two sides, which are located at below fixed block, is provided with receiving pipe, in the receiving pipe below extension bar
It is provided with spring, wherein one end is provided with jacking block to the spring, is provided with cushion in the accommodating chamber bottom.
It is that cavity is arranged in the middle part of the magnetic force column preferably, being provided with magnetic force column on the pedestal.
Preferably, being provided with cylinder-shaped magnet in the magnetic force column cavity, the cylinder-shaped magnet is alnico magnets.
Preferably, in the accommodating chamber bottom insertion magnetic force column cavity.
Preferably, wherein idler wheel is withstood in one end to the jacking block.
Preferably, the rack for test tube is the rack for test tube that acrylic is integrally formed.
The utility model has the technical effect that following aspect: test tube being placed in accommodating chamber, test tube is because of gravity
Reason moves down and pushes idler wheel to both sides, until test tube bottom and the touching of accommodating chamber bottom connection, makes it possible to full
The placement of the various sizes of Reagent Tube of foot is not reducing nucleic acid extraction effect but also Reagent Tube remains vertical state
Under the premise of, additionally it is possible to meet various different sample nucleic acids the needs of extracting.
Detailed description of the invention
Fig. 1 is a kind of structural schematic diagram of paramagnetic particle method nucleic acid magnetic frame of the utility model；
Fig. 2 is a kind of A enlarged structure schematic diagram of paramagnetic particle method nucleic acid magnetic frame of the utility model.
Specific embodiment
Below in conjunction with attached drawing 1-2, specific embodiment of the present utility model is described in further detail, so that the utility model
Technical solution is more readily understood and grasps.
In the present embodiment, it is to be understood that term " centre ", "upper", "lower", " top ", " right side ", " left end ",
" top ", " back side ", " middle part ", etc. instructions orientation or positional relationship be based on the orientation or positional relationship shown in the drawings, only
It is of the invention for ease of description, rather than the device or element of indication or suggestion meaning must have a particular orientation, with spy
Fixed orientation construction and operation, therefore be not considered as limiting the invention.
In addition, the connection or fixed form between component if not otherwise specified in this embodiment, connection or solid
Determine mode can for fixed by bolt commonly used in the prior art or pin fix or pin shaft connection etc. modes, therefore, this
It is not described in detail in embodiment.
As shown in Figs. 1-2, a kind of paramagnetic particle method nucleic acid magnetic frame includes pedestal 1, is equipped with test tube above the pedestal 1
Frame 2, the rack for test tube 2 are the rack for test tube 2 that acrylic is integrally formed, and good toughness, hardness is high, not cracky, Neng Gouyan
The service life of long rack for test tube 2.The rack for test tube 2 is respectively support plate 21 and placement plate 22, and the setting of placement plate 22 is being propped up
Above fagging 21, accommodating chamber 3 is provided on 22 surface of placement plate, the accommodating chamber 3 is for placing Reagent Tube.The receiving
3 inner wall two sides of chamber are provided with fixed block 31, and first connecting rod 32, the first connecting rod 32 are provided with below the fixed block 31
Lower section is hinged with the second connecting rod 33, and idler wheel 34,3 inner wall two sides of the accommodating chamber position are equipped with below second connecting rod 33
It is provided with below fixed block 31 and accommodates pipe 35, be provided with spring 351 in the receiving pipe 35, the spring 351 wherein one end
It is provided with jacking block 352, wherein idler wheel 34 is withstood in one end to the jacking block 352, by the way that Reagent Tube to be placed in accommodating chamber 3, with closing
Idler wheel 34 slowly declines, and until test tube bottom and the touching of 3 bottom connection of accommodating chamber, while idler wheel 34 also presss from both sides Reagent Tube
Hold, so that Reagent Tube remains vertical state, under the premise of not reducing nucleic acid extraction effect, additionally it is possible to meet it is various not
With the demand of sample nucleic acid extraction.
It is provided with magnetic force column 11 on the pedestal 1, is arranged in the middle part of the magnetic force column 11 for cavity, 11 cavity of magnetic force column
It is inside provided with cylinder-shaped magnet 111, the cylinder-shaped magnet 111 is alnico magnets, and magnetic force column is inserted into 3 bottom of accommodating chamber
In 11 cavitys, comprehensive magnetic field is formed by cylinder-shaped magnet 111 and adsorbs magnetic bead, so that the magnetic force of magnetic greatly enhances, magnetic
The adsorption capacity of pearl is not decayed with enrichment with magnetic bead, to enhance the adaptability of magnetic bead collection, so that magnetic bead is uniformly fully inhaled
It is attached on inboard wall of test tube, greatly improves the efficiency of nucleic acid extraction, avoid magnetic too small and lead to the halfway problem of magnetic bead magnetic.
Principle explanation: when in use, test tube being placed in accommodating chamber 3, and test tube slowly declines, and until test tube bottom and is accommodated
Until 3 bottom connection of chamber touches, the placement of entire test tube is realized, finish if extracting, directly take out test tube, then jacking block 352
Because losing the extruding of test tube, so that second spring 351 is no longer the working condition squeezed, then jacking block 352 is driven to return to original position,
It prepares for the placement of test tube next time.
The utility model has the technical effect that following aspect: test tube being placed in accommodating chamber, test tube is because of gravity
Reason moves down and pushes idler wheel to both sides, until test tube bottom and the touching of accommodating chamber bottom connection, makes it possible to full
The placement of the various sizes of Reagent Tube of foot is not reducing nucleic acid extraction effect but also Reagent Tube remains vertical state
Under the premise of, additionally it is possible to meet various different sample nucleic acids the needs of extracting.
Certainly, the representative instance of above only the utility model, in addition to this, the utility model can also have other a variety of
Specific embodiment, all technical solutions formed using equivalent substitution or equivalent transformation all fall within the requires of the utility model protection
Within the scope of.
Claims (6)
1. a kind of paramagnetic particle method nucleic acid magnetic frame includes pedestal (1), it is characterised in that: be equipped with test tube above the pedestal (1)
Frame (2), the rack for test tube (2) are respectively support plate (21) and placement plate (22), and the placement plate (22) is arranged in support plate
(21) it above, is provided with accommodating chamber (3) on placement plate (22) surface, accommodating chamber (3) the inner wall two sides are provided with fixation
Block (31), fixed block (31) lower section are provided with first connecting rod (32), first connecting rod (32) the underside connection
Have the second connecting rod (33), is equipped with idler wheel (34) below second connecting rod (33), accommodating chamber (3) the inner wall two sides position
It is provided with receiving pipe (35) below fixed block (31), is provided with spring (351), the spring in the receiving pipe (35)
(351) wherein one end is provided with jacking block (352).
2. a kind of paramagnetic particle method nucleic acid magnetic frame as described in claim 1, it is characterised in that: be provided with magnetic on the pedestal (1)
Power column (11), magnetic force column (11) middle part are that cavity is arranged.
3. a kind of paramagnetic particle method nucleic acid magnetic frame as claimed in claim 2, it is characterised in that: set in magnetic force column (11) cavity
It is equipped with cylinder-shaped magnet (111), the cylinder-shaped magnet (111) is alnico magnets.
4. a kind of paramagnetic particle method nucleic acid magnetic frame as described in one of claim 1-2, it is characterised in that: accommodating chamber (3) bottom
Portion is inserted into magnetic force column (11) cavity.
5. a kind of paramagnetic particle method nucleic acid magnetic frame as described in claim 1, it is characterised in that: the jacking block (352) wherein one end
Withstand idler wheel (34).
6. a kind of paramagnetic particle method nucleic acid magnetic frame as described in claim 1, it is characterised in that: the rack for test tube (2) is acrylic
Integrally formed rack for test tube (2).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821499948.6U CN208791661U (en) | 2018-09-13 | 2018-09-13 | A kind of paramagnetic particle method nucleic acid magnetic frame |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821499948.6U CN208791661U (en) | 2018-09-13 | 2018-09-13 | A kind of paramagnetic particle method nucleic acid magnetic frame |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN208791661U true CN208791661U (en) | 2019-04-26 |
Family
ID=66209568
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201821499948.6U Expired - Fee Related CN208791661U (en) | 2018-09-13 | 2018-09-13 | A kind of paramagnetic particle method nucleic acid magnetic frame |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN208791661U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110241009A (en) * | 2019-07-17 | 2019-09-17 | 上海鹍远医疗器械有限公司 | A kind of magnetic force frame module |
| CN111925906A (en) * | 2020-06-24 | 2020-11-13 | 温州医科大学 | Be used for gene diagnosis to use sample separator |
-
2018
- 2018-09-13 CN CN201821499948.6U patent/CN208791661U/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110241009A (en) * | 2019-07-17 | 2019-09-17 | 上海鹍远医疗器械有限公司 | A kind of magnetic force frame module |
| CN111925906A (en) * | 2020-06-24 | 2020-11-13 | 温州医科大学 | Be used for gene diagnosis to use sample separator |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20190426 Termination date: 20190913 |
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| CF01 | Termination of patent right due to non-payment of annual fee |