CN210514091U

CN210514091U - Diagnostic reagent sampling and detecting integrated device

Info

Publication number: CN210514091U
Application number: CN201921041819.7U
Authority: CN
Inventors: 陶心江
Original assignee: Individual
Current assignee: Individual
Priority date: 2019-07-04
Filing date: 2019-07-04
Publication date: 2020-05-12
Anticipated expiration: 2029-07-04

Abstract

The utility model discloses a diagnostic reagent sampling detects integrative device, it is sealed including collecting the storehouse, detecting storehouse, detachably collect the first lid in storehouse and detachably seal detect the second lid in storehouse, collect the storehouse with detect the bottom intercommunication in storehouse, set up the through-hole that is used for putting in the test paper strip on the second lid. The utility model discloses realize detecting laborsaving and non-staining test paper strip, it is easy and simple to handle.

Description

Diagnostic reagent sampling and detecting integrated device

Technical Field

The utility model relates to a medical instrument technical field of external diagnosis especially relates to an integrative device of diagnostic reagent sampling detection.

Background

In the current medical health system for in vitro diagnosis of living body secretion or excrement sampling test, the prior art adopts a test device comprising a detector, a test strip disposed in the detector, a collector detachably accommodated in the detector, and an excrement collecting member detachably sealing the collector, and at least one needling component is disposed on a side of the bottom surface of the detector facing the collector; when the collector collects the excrement sample, the target sample diluting solution is mixed with the excrement sample in the collector, the top of the collector is pressed down, the needling component pierces the bottom of the collector, the mixed sample solution flows into the detector, and the lower end of the test strip contacts with the sample solution, so that strip climbing is facilitated. For an operator with lower hand strength, the collector is not pressed in place, the bottom of the collector is not pierced by the needling component, so that the detection fails, or the needling component pierces a little, so that the sample solution flows into the detector at a low speed, so that the detection is slow.

SUMMERY OF THE UTILITY MODEL

The utility model provides an integrative device of diagnostic reagent sampling test realizes detecting laborsavingly, and the non-staining test paper strip, and is easy and simple to handle.

The utility model adopts the following technical scheme:

integrative device of diagnostic reagent sampling detection, its characterized in that is sealed including collecting the storehouse, detecting the storehouse, detachably collect the first lid in storehouse and detachably seal detect the second lid in storehouse, collect the storehouse with detect the bottom intercommunication in storehouse, set up the through-hole that is used for puting in the test paper strip on the second lid.

Preferably, the first cover body and the second cover body are integrally formed cover bodies.

Optionally, the through holes are provided in the second cover.

Preferably, a third cover body for sealing the through hole is arranged on the second cover body.

Preferably, the third cover body comprises a sealing part, a cover body part and a handheld part, wherein the sealing part can be placed in the through hole, the sealing part is fixedly connected with the lower part of the cover body part, and the cover body part and the handheld part are connected or integrally formed;

the second cover body is provided with a groove for clamping the cover body part so as to stably seal the through hole.

Preferably, the inner wall of the detection bin is provided with a plurality of limiting parts which enable the test strip to be in a vertical state.

Furthermore, a limiting part for limiting the bottom position of the test strip is arranged above a communication port for communicating the collection bin with the bottom of the detection bin.

Preferably, the bottom of the first cover body is provided with a collecting piece.

Further, gather the piece including gathering stick and shovel spoon, gather stick one end intercommunication the bottom of first lid, the other end intercommunication the shovel spoon, be equipped with the weeping hole on the spoon face of shovel spoon.

Preferably, the collection chamber and the detection chamber are made of transparent materials. The test paper strip detection result is conveniently observed to this scheme, omits observation window structure setting, simplifies production technology. And the blow molding manufacturing process is adopted, so that the manufacturing cost is low.

Advantageous effects

The utility model discloses put into target sample earlier and detect liquid, mix and shake even back, the test paper strip is put into to the through-hole on the rethread lid and is detected, has avoided operating personnel to press hard among the prior art and has collected the storehouse top with mixing target sample and detection liquid, easy operation, convenience.

Drawings

Fig. 1 is a schematic diagram of a general assembly structure of a diagnostic reagent sampling and detection integrated device according to various embodiments of the present invention;

FIG. 2 is a sectional view of the integrated diagnostic reagent sampling/detection apparatus A-A according to example 1 of the present invention;

FIG. 3 is a sectional view of the integrated diagnostic reagent sampling/testing device A-A according to example 2 of the present invention;

fig. 4 is one of the schematic exploded structural diagrams of the diagnostic reagent sampling and detection integrated device provided in embodiment 2 of the present invention;

fig. 5 is a second schematic exploded view of the integrated diagnostic reagent sampling and testing device according to embodiment 2 of the present invention.

Detailed Description

The structures referred to in the present invention or these terms of art used are further described below.

Detection of

"detecting" means assaying or testing for the presence of a substance or material, such as, but not limited to, a chemical, organic compound, inorganic compound, metabolic product, drug or drug metabolite, organic tissue or metabolite of organic tissue, nucleic acid, protein, or polymer. In addition, detection indicates the amount of the test substance or material. Further, the assay means immunodetection, chemical detection, enzyme detection, and the like.

Test paper strip

The specific structure and detection principle of the test strip of the present invention are well known in the art. The common reagent strip comprises a sample receiving area, a labeling area, a detection area and a water absorption area, wherein the detection area comprises necessary chemical substances capable of detecting whether an analyte is contained, after the detection is finished, a detection line for indicating a result and a control line are formed on the detection area, the detection reagent strip which is generally commonly used for the control line is a nitrocellulose membrane reagent strip, namely, the detection area comprises a nitrocellulose membrane (NC membrane), specific binding molecules are fixed on the nitrocellulose membrane to display the end of the detection, and the nitrocellulose membrane or a nylon membrane and the like can be used. Typically the test strip is between 3mm and 6mm wide.

Type of analyte

Examples of analytes that can be stably detected by the present invention include, but do not include, human chorionic gonadotropin (hCG), Luteinizing Hormone (LH), ovarian estrogen (FSH), Hepatitis C Virus (HCV), Hepatitis B Virus (HBV), hepatitis b surface antigen, helicobacter pylori antigen, rotavirus antigen, adenovirus antigen, fecal transferrin, aids virus and any drugs of abuse. The analyte can be detected in any liquid or liquefied sample, such as urine, saliva, stool, nasal secretion, vaginal secretion, wound secretion, blood, plasma, or serum. Examples of other analytes are creatinine, bilirubin, nitrite, proteins (non-specific), blood, leukocytes, blood glucose, heavy metals and toxins, bacterial components (e.g., specific proteins and sugars of a particular type of bacteria, such as E.coli 0157: H7, Staphylococcus aureus, Salmonella, Clostridium perfringens, Campylobacter, Listeria monocytogenes, Vibrio enteritis, or Hierobacter X. X). Any other analyte suitable for lateral flow assay formats may be detected with the present device.

Type of sample

Any type of sample can be tested with the device of the present invention, including body fluids (e.g., urine and other body fluids, as well as clinical samples). Liquid samples may be derived from solid or semi-solid samples, including stool, biological tissue, and food samples. These solid and semi-solid samples may be converted to liquid samples by any suitable method, such as mixing in a suitable liquid, mincing, macerating, incubating, dissolving, or enzymatically hydrolyzing the solid sample (e.g., water, phosphate buffer, or other buffer). "biological samples" include samples derived from living animals, plants and food, and also include urine, saliva, blood and blood components, cerebrospinal fluid, vaginal swabs, semen, feces, sweat, secretions, tissues, organs, tumors, cultures of tissues and organs, cell cultures and conditioned media therein, whether human or animal. Food samples include processed food ingredients and end products, meat, cheese, wine, milk and drinking water. Plant samples include samples derived from any plant, plant tissue, plant cell culture, and conditioned medium therein. "environmental samples" are those samples derived from the environment (e.g., lake water samples or samples of other bodies of water, sewage samples, soil samples, groundwater samples, seawater samples, samples of waste water). Sewage and associated waste may also be included in the environmental sample.

In the following detailed description, reference is made to the accompanying drawings, which form a part hereof, and in which is shown by way of illustration specific embodiments in which the invention may be practiced. We do not exclude that the invention can also be implemented with other embodiments and that the structure of the invention can be changed without violating the scope of the invention.

Example 1

Referring to fig. 1, the present invention provides a schematic structural diagram of an integrated diagnostic reagent sampling and detecting device according to embodiment 1. The device comprises a collection bin 110, a detection bin 120, a first cover body for detachably sealing the collection bin, and a second cover body for detachably sealing the detector. The first cover and the second cover are integrally formed covers 130. The cover 130 includes a bin body cover portion 131 and a plurality of bin

body sealing portions

132 and 133 disposed below the bin body cover portion 131, the bin

body sealing portions

132 and 133 are made of elastic materials, such as rubber and silica gel, when the bin

body sealing portions

132 and 133 are respectively inserted into the bin openings of the corresponding collecting bin 110 and detecting bin 120, the collecting bin 110 and detecting bin 120 are sealed by elastic deformation of the bin

body sealing portions

132 and 133. The collection bin 101 is communicated with the bottom of the detection bin 102, and a through hole 140 for putting in the test strip is formed in the cover 130 (i.e., the second cover) corresponding to the position of the bin opening of the detection bin 120.

During the use, open lid 130, put into the test solution in collecting the storehouse 110 earlier, put into the target sample again, cover lid 130, the dilution solution after both shake evenly gets into and detects storehouse 120 through intercommunicating pore 170, put test paper strip 1 into detecting storehouse 120 through-hole 140 this moment, the lower extreme water absorption area contact dilution solution of test paper strip shows at the color development district of test paper strip to the analyte of detection target sample, operating personnel can observe the test paper strip testing result through transparent collection storehouse 110 and detection storehouse 120.

Example 2

Referring to fig. 1, the present invention provides a schematic structural diagram of an integrated diagnostic reagent sampling and detecting device of embodiment 2. The device comprises a collection bin 210, a detection bin 220, a first cover body for detachably sealing the collection bin, and a second cover body for detachably sealing the detector. The first cover and the second cover are integrally formed covers 230. The cover 230 includes a cover 231 and a plurality of

seals

232, 233 disposed under the cover 231, the

seals

232, 233 are made of elastic material, such as rubber, silica gel, etc., when the

seals

232, 233 are inserted into the corresponding collection bin 220 and the detection bin 220, respectively, the elastic deformation of the

seals

232, 233 seals the collection bin 220 and the detection bin 220. The collection bin 202 is communicated with the bottom of the detection bin 202, and a through hole 240 for dispensing the test strip is formed in a cover 230 (i.e., a second cover) corresponding to the position of the bin opening of the detection bin 220. One or more through holes 240 may be provided.

The cover 230 is provided with a third cover 250 for sealing the through hole 240. The third cover 250 comprises a cover sealing part 251, a cover part 252 and a handheld part 253, the cover sealing part 251 can be placed in the through hole 240, the cover sealing part 251 is fixedly connected with the lower part of the cover part 252, the cover part 252 and the handheld part 253 can be connected in a bending mode, the cover part 252 and the handheld part 253 can be made of PVC, and after the handheld part 253 is bent first by an operator, the third cover 250 can be pulled out upwards with force by pinching the handheld part 253 with two fingers.

In another embodiment of the third cover 250, the cover sealing portion 251, the third cover portion 252 and the third handle portion 253 are integrally formed, the third cover 250 is made of an elastic material, such as rubber, silicon gel, etc., the handle portion 253 is in a sheet shape, top planes of the cover portion 252 and the handle portion 253 are located on the same horizontal plane, a thickness of the handle portion 253 is smaller than that of the cover portion 252, and the cover sealing portion 251 is fixedly connected with a lower portion of the cover portion 252.

Storehouse body lid portion 231 is elastic material, sets up the echelonment recess on it, and first step recess 2311 is used for centre gripping lid portion 252 in order to stabilize sealed through-hole 240, and second step recess 2312 is used for placing handheld portion 253, and the bottom area of second step recess is greater than handheld portion, and the operating personnel finger of being convenient for takes out handheld portion 253 or bends handheld portion 253.

The cover body 230 (namely, the first cover body) corresponding to the bin mouth position of the collecting bin 210 is fixedly connected with the collecting piece below the bin body sealing part 232, the collecting piece comprises a collecting rod 261 and a scoop 262, one end of the collecting rod 261 is communicated with the bottom of the bin body sealing part 232, the other end of the collecting rod 261 is communicated with the scoop 262, and when a solid or semisolid target sample is collected, a liquid leakage hole is formed in the scoop surface of the scoop 262 to remove redundant liquid.

In use, the cover 230 is opened, and the third cover 250 is covered on the cover 230; firstly, collecting a target sample by a collecting piece, putting the target sample into the collecting bin 210, and then putting detection liquid, wherein the steps of putting the target sample and the detection liquid can be interchanged; cover lid 230, both shake the dilute solution after the even and pass through the intercommunicating pore 270 and get into and detect storehouse 220, at this moment, the finger takes out stealthy handheld portion 253 or the handheld portion 253 of bending in the second ladder recess, upwards extract third lid 250, expose through-hole 240, put into the test storehouse 220 through-hole 240 with test paper strip 1, the lower extreme absorbing area contact dilute solution of test paper strip, show in the color development district of test paper strip, thereby detect the analyte of target sample, operating personnel can pass through transparent collection storehouse 210 and detection storehouse 220, observe the test paper strip testing result.

Example 3

Based on embodiment 2, the inner wall of the detection chamber 220 is provided with a plurality of position-limiting parts 221 for enabling the test strip to be in a vertical state. The bottom of the test strip contacts the bottom of the detection chamber 220.

In another embodiment, the inner wall of the detection bin 220 is provided with a plurality of position-limiting parts 221 for enabling the test strip to be in a vertical state, and the position above the communication port 270 for communicating the collection bin 210 and the bottom of the detection bin 220 is provided with a position-limiting part 222 for limiting the position of the bottom of the test strip. The liquid level of the diluted solution after mixing the target sample and the detection solution is higher than the limiting part 222, so that the lower water absorption area of the test strip is contacted with the diluted solution for detection.

Claims

1. Integrative device of diagnostic reagent sampling detection, its characterized in that is sealed including collecting the storehouse, detecting the storehouse, detachably collect the first lid in storehouse and detachably seal detect the second lid in storehouse, collect the storehouse with detect the bottom intercommunication in storehouse, set up the through-hole that is used for puting in the test paper strip on the second lid.

2. The integrated diagnostic reagent sampling and testing device of claim 1, wherein the first cover and the second cover are integrally formed covers.

3. The integrated diagnostic reagent sampling and testing device of claim 1, wherein a plurality of through holes are arranged on the second cover body.

4. The integrated diagnostic reagent sampling and testing device of claim 1, wherein a third cover body for sealing the through hole is disposed on the second cover body.

5. The integrated diagnostic reagent sampling and detecting device according to claim 4, wherein the third cover comprises a sealing portion, a cover portion and a handheld portion, the sealing portion can be placed in the through hole, the sealing portion is fixedly connected with the lower portion of the cover portion, and the cover portion is connected with or integrally formed with the handheld portion;

6. The integrated diagnostic reagent sampling and testing device of claim 1, wherein the inner wall of the testing chamber is provided with a plurality of limiting parts which enable the test strip to be in a vertical state.

7. The integrated diagnostic reagent sampling and testing device of claim 6, wherein a position limiting part for limiting the position of the bottom of the test strip is arranged above a communication port for communicating the collection chamber and the bottom of the testing chamber.

8. The integrated diagnostic reagent sampling and testing device of claim 1, wherein the bottom of the first cover body is provided with a collecting piece.

9. The integrated diagnostic reagent sampling and detecting device according to claim 8, wherein the collecting member comprises a collecting rod and a scoop, one end of the collecting rod is communicated with the bottom of the first cover body, the other end of the collecting rod is communicated with the scoop, and a liquid leakage hole is formed in the scoop surface of the scoop.

10. The integrated diagnostic reagent sampling and testing device of any one of claims 1 to 9, wherein the collecting chamber and the testing chamber are made of transparent materials.