CN210394393U - Virus nucleic acid reagent separation equipment based on magnetic bead separation technology - Google Patents
Virus nucleic acid reagent separation equipment based on magnetic bead separation technology Download PDFInfo
- Publication number
- CN210394393U CN210394393U CN201921182839.6U CN201921182839U CN210394393U CN 210394393 U CN210394393 U CN 210394393U CN 201921182839 U CN201921182839 U CN 201921182839U CN 210394393 U CN210394393 U CN 210394393U
- Authority
- CN
- China
- Prior art keywords
- cabinet body
- magnetic bead
- nucleic acid
- centrifugal mechanism
- reagent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 238000000926 separation method Methods 0.000 title claims abstract description 31
- 239000011324 bead Substances 0.000 title claims abstract description 26
- 150000007523 nucleic acids Chemical class 0.000 title claims abstract description 16
- 102000039446 nucleic acids Human genes 0.000 title claims abstract description 16
- 108020004707 nucleic acids Proteins 0.000 title claims abstract description 16
- 241000700605 Viruses Species 0.000 title claims abstract description 14
- 239000012445 acidic reagent Substances 0.000 title claims abstract description 13
- 239000003153 chemical reaction reagent Substances 0.000 claims abstract description 28
- 230000007246 mechanism Effects 0.000 claims abstract description 22
- 238000009434 installation Methods 0.000 claims description 8
- 238000005192 partition Methods 0.000 claims description 4
- 238000005119 centrifugation Methods 0.000 claims description 2
- 230000003612 virological effect Effects 0.000 claims 4
- 230000004071 biological effect Effects 0.000 abstract description 3
- 239000012620 biological material Substances 0.000 abstract description 3
- 230000000694 effects Effects 0.000 description 4
- 230000004075 alteration Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000008827 biological function Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
Images
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- Centrifugal Separators (AREA)
Abstract
The utility model discloses a virus nucleic acid reagent splitter based on magnetic bead separation technique, including the cabinet body, centrifugal mechanism installs the top at internal wall of cabinet, centrifugal mechanism's top is run through the cabinet body and is extended to its outside rather than swing joint, the control box is installed on the right side at internal wall top of cabinet, the below fixed mounting that just is located centrifugal mechanism on the inner wall of the cabinet body has the baffle, the cabinet door is installed to the front side of the cabinet body. The utility model discloses a set up centrifugal mechanism, adopt magnetic bead separation technique cooperation centrifugal motion to separate the virus nucleic acid in the reagent pipe for separation speed has improved separation efficiency, and repeatability is more ideal moreover, and easy operation does not need expensive instrument and equipment simultaneously, does not influence by the biological property and the function of detached cell or other biomaterial, brings very big facility for separation work.
Description
Technical Field
The utility model relates to a virus nucleic acid reagent technical field specifically is a virus nucleic acid reagent splitter based on magnetic bead separation technique.
Background
At present, in the prior art, the separation speed is relatively slow, the efficiency is relatively low, the operation is complex, expensive instruments and equipment are needed in the separation process of nucleic acid viruses, the biological properties and functions of separated cells or other biological materials are influenced, and great inconvenience is brought to the separation work.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to provide a virus nucleic acid reagent splitter based on magnetic bead separation technique to solve the problem that proposes in the above-mentioned background art.
In order to achieve the above object, the utility model provides a following technical scheme: a virus nucleic acid reagent separation device based on a magnetic bead separation technology comprises a cabinet body and a centrifugal mechanism, wherein the centrifugal mechanism is installed at the top of the inner wall of the cabinet body, the top of the centrifugal mechanism penetrates through the cabinet body and extends to the outside of the cabinet body to be movably connected with the cabinet body, a control box is installed on the right side of the top of the inner wall of the cabinet body, a partition plate is fixedly installed on the inner wall of the cabinet body and below the centrifugal mechanism, and a cabinet door is installed on the front side of the cabinet body;
the centrifugal mechanism comprises a motor, the motor is arranged at the top of the inner wall of the cabinet body, a rotating shaft is fixedly arranged on an output shaft of the motor, the top end of the rotating shaft penetrates through the cabinet body and extends to the outside of the cabinet body to be movably connected with the cabinet body, a rotating table is fixedly connected to the top end of the rotating shaft, a rotating plate is arranged at the top of the rotating table, a reagent tube is arranged at the top of the rotating plate, a fixing groove matched with the reagent tube is formed in the top of the rotating table, the bottom end of the reagent tube sequentially penetrates through the rotating plate and the fixing groove from top to bottom and extends to the inside of the fixing groove, the bottom of the reagent tube is in contact with the fixing groove, a tube plug is arranged at the top of the reagent tube, a magnetic bead box is arranged at the top of the rotating plate, a detachable box cover is arranged at the top of the magnetic bead box, the top of installation cover is provided with the threaded rod, the bottom of threaded rod runs through installation cover and adapter sleeve and extends to the outside of adapter sleeve from last to down in proper order.
Preferably, the top of the cabinet body is provided with an annular slide rail, the surface of the annular slide rail is movably connected with a slide block, and the top of the slide block is fixedly connected with the rotating table.
Preferably, the bottom fixedly connected with stopper of rotor plate, the bottom of stopper runs through the rotor table and extends to its inside and swing joint.
Preferably, the left side and the right side of the top of the rotating plate are both fixedly connected with handles.
Preferably, a nut is connected to the surface of the threaded rod and below the connecting sleeve in a threaded manner.
Compared with the prior art, the beneficial effects of the utility model are as follows:
1. the utility model discloses a set up centrifugal mechanism, adopt magnetic bead separation technique cooperation centrifugal motion to separate the virus nucleic acid in the reagent pipe for separation speed has improved separation efficiency, and repeatability is more ideal moreover, and easy operation does not need expensive instrument and equipment simultaneously, does not influence by the biological property and the function of detached cell or other biomaterial, brings very big facility for separation work.
2. The utility model discloses an annular slide rail and slider mutually support for the revolving stage is rotatory more stable, has played the effect of advancing line location to the rotor plate through setting up the stopper, supports the rotor plate simultaneously, prevents that reagent pipe from receiving the damage, has played the effect of the rotor plate of being convenient for to take through setting up the handle, has played through setting up the nut and has carried out spacing effect to the screw rod.
Drawings
FIG. 1 is a sectional view of the front view of the present invention;
FIG. 2 is a schematic view of the structure A-A of FIG. 1 according to the present invention;
fig. 3 is a schematic structural diagram of the cabinet body of the present invention.
In the figure: the device comprises a cabinet body 1, a centrifugal mechanism 2, a motor 21, a rotating shaft 22, a rotating table 23, a rotating plate 24, a reagent tube 25, a fixed groove 26, a magnetic bead box 27, a connecting sleeve 28, a mounting sleeve 29, a threaded rod 210, a control box 3, a partition plate 4, an annular sliding rail 5, a sliding block 6, a limiting block 7, a handle 8 and a nut 9.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
Referring to fig. 1-3, a virus nucleic acid reagent separation device based on a magnetic bead separation technology comprises a cabinet body 1 and a centrifugal mechanism 2, wherein the centrifugal mechanism 2 is installed at the top of the inner wall of the cabinet body 1, the top of the centrifugal mechanism 2 penetrates through the cabinet body 1 and extends to the outside of the cabinet body to be movably connected with the cabinet body, a control box 3 is installed on the right side of the top of the inner wall of the cabinet body 1, a controller is installed in the control box 3 and can control the rotating speed of the centrifugal mechanism 2, a partition plate 4 is fixedly installed on the inner wall of the cabinet body 1 and below the centrifugal mechanism 2, and a cabinet door is installed on the front side of.
Referring to fig. 1-3, the centrifugal mechanism 2 includes a motor 21, the motor 21 is a low speed motor, the motor 21 is installed on the top of the inner wall of the cabinet 1, a rotating shaft 22 is fixedly installed on an output shaft of the motor 21, a top end of the rotating shaft 22 penetrates through the cabinet 1 and extends to the outside of the cabinet to be movably connected therewith, a rotating table 23 is fixedly connected to a top end of the rotating shaft 22, an annular slide rail 5 is installed on the top of the cabinet 1, a slide block 6 is movably connected to a surface of the annular slide rail 5, a top portion of the slide block 6 is fixedly connected with the rotating table 23, the rotating table 23 is made to rotate more stably by the cooperation of the annular slide rail 5 and the slide block 6, a rotating plate 24 is disposed on the top portion of the rotating table 23, a limiting block 7 is fixedly connected to a bottom portion of the rotating plate 24, a bottom end of the limiting block 7 penetrates, meanwhile, the rotating plate 24 is supported, the reagent tube 25 is prevented from being damaged, the reagent tube 25 is installed at the top of the rotating plate 24, the handles 8 are fixedly connected to the left side and the right side of the top of the rotating plate 24, the rotating plate 24 is convenient to take by arranging the handles 8, the top of the rotating table 23 is provided with a fixing groove 26 matched with the reagent tube 25, a protective pad is installed in the fixing groove 26 and can protect the reagent tube 25, the bottom end of the reagent tube 25 sequentially penetrates through the rotating plate 24 and the fixing groove 26 from top to bottom and extends into the fixing groove 26, the reagent tube 25 can be detached from the rotating plate 24 and is convenient to take the reagent tube 25, the bottom of the reagent tube 25 is in contact with the fixing groove 26, the reagent tube 25 is a stainless steel reagent tube, the top of the reagent tube 25 is provided with a tube plug, the top of the rotating plate 24 is provided with a magnetic bead box 27, and the top of the magnetic bead box 27, the equal fixedly connected with adapter sleeve 28 in the left and right sides of rotating platform 23, the equal fixedly connected with installation cover 29 in the left and right sides of rotor plate 24, the top of installation cover 29 is provided with threaded rod 210, threaded rod 210's bottom is from last to running through installation cover 29 and adapter sleeve 28 in proper order down and extending to adapter sleeve 28's outside, threaded rod 210's the surface and the below threaded connection who is located adapter sleeve 28 have nut 9, have played through setting up nut 9 and have carried out spacing effect to threaded rod 210.
The working principle is as follows: during the use, open the stopcock, place the virus in reagent pipe 25, and seal with the stopcock, open the lid, place the magnetic bead in the inside of magnetic bead box 27, and seal magnetic bead box 27 with the lid, it is rotatory to drive pivot 22 through control box 3 control motor 21, pivot 22 drives rotor plate 24 low-speed rotation through revolving stage 23, rotor plate 24 drives reagent pipe 25 rotatory, carry out the centrifugation to the virus in the reagent pipe 25 and cooperate the magnetic bead in the magnetic bead box 27 to separate it simultaneously.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (5)
1. The utility model provides a virus nucleic acid reagent splitter based on magnetic bead separation technique, includes cabinet body (1), centrifugation mechanism (2), its characterized in that: the centrifugal mechanism (2) is mounted at the top of the inner wall of the cabinet body (1), the top of the centrifugal mechanism (2) penetrates through the cabinet body (1) and extends to the outside of the cabinet body to be movably connected with the cabinet body, a control box (3) is mounted on the right side of the top of the inner wall of the cabinet body (1), a partition plate (4) is fixedly mounted on the inner wall of the cabinet body (1) and located below the centrifugal mechanism (2), and a cabinet door is mounted on the front side of the cabinet body (1);
the centrifugal mechanism (2) comprises a motor (21), the motor (21) is installed at the top of the inner wall of the cabinet body (1), a rotating shaft (22) is fixedly installed on an output shaft of the motor (21), the top end of the rotating shaft (22) penetrates through the cabinet body (1) and extends to the outside of the cabinet body and is movably connected with the rotating shaft, a rotating table (23) is fixedly connected to the top end of the rotating shaft (22), a rotating plate (24) is arranged at the top of the rotating table (23), a reagent tube (25) is installed at the top of the rotating plate (24), a fixing groove (26) matched with the reagent tube (25) is formed in the top of the rotating table (23), the bottom end of the reagent tube (25) sequentially penetrates through the rotating plate (24) and the fixing groove (26) from top to bottom and extends to the inside of the fixing groove (26), and the bottom of the reagent tube (25) is in, the top of reagent pipe (25) is provided with the stopcock, magnetic bead box (27) are installed at the top of rotor plate (24), the detachable lid is installed at the top of magnetic bead box (27), the equal fixedly connected with adapter sleeve (28) of the left and right sides of rotation platform (23), the equal fixedly connected with installation cover (29) of the left and right sides of rotor plate (24), the top of installation cover (29) is provided with threaded rod (210), the bottom of threaded rod (210) is from last to running through installation cover (29) and adapter sleeve (28) down in proper order and extending to the outside of adapter sleeve (28).
2. A viral nucleic acid reagent separation device based on a magnetic bead separation technology according to claim 1, wherein: annular slide rail (5) are installed at the top of the cabinet body (1), the surface swing joint of annular slide rail (5) has slider (6), the top and the revolving platform (23) fixed connection of slider (6).
3. A viral nucleic acid reagent separation device based on a magnetic bead separation technology according to claim 1, wherein: the bottom fixedly connected with stopper (7) of rotor plate (24), the bottom of stopper (7) runs through and rotates platform (23) and extend to its inside rather than swing joint.
4. A viral nucleic acid reagent separation device based on a magnetic bead separation technology according to claim 1, wherein: the left side and the right side of the top of the rotating plate (24) are fixedly connected with handles (8).
5. A viral nucleic acid reagent separation device based on a magnetic bead separation technology according to claim 1, wherein: the surface of the threaded rod (210) is in threaded connection with a nut (9) below the connecting sleeve (28).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201921182839.6U CN210394393U (en) | 2019-07-25 | 2019-07-25 | Virus nucleic acid reagent separation equipment based on magnetic bead separation technology |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201921182839.6U CN210394393U (en) | 2019-07-25 | 2019-07-25 | Virus nucleic acid reagent separation equipment based on magnetic bead separation technology |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN210394393U true CN210394393U (en) | 2020-04-24 |
Family
ID=70358013
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201921182839.6U Expired - Fee Related CN210394393U (en) | 2019-07-25 | 2019-07-25 | Virus nucleic acid reagent separation equipment based on magnetic bead separation technology |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN210394393U (en) |
-
2019
- 2019-07-25 CN CN201921182839.6U patent/CN210394393U/en not_active Expired - Fee Related
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| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20200424 |
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| CF01 | Termination of patent right due to non-payment of annual fee |