CN210352656U - Experimental apparatus for researching social behaviors of mice - Google Patents
Experimental apparatus for researching social behaviors of mice Download PDFInfo
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- CN210352656U CN210352656U CN201921240649.5U CN201921240649U CN210352656U CN 210352656 U CN210352656 U CN 210352656U CN 201921240649 U CN201921240649 U CN 201921240649U CN 210352656 U CN210352656 U CN 210352656U
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Abstract
An experimental apparatus for researching social behaviors of mice comprises a box body with multiple grids and a metal bar cage for fixing the mice, and is characterized in that a long-strip notch is arranged below the front side of each grid box body, a drawable plate is arranged in the long-strip notch, and drawable plates with different colors are arranged in the long-strip notch; when the drawable plate completely extends into each case body, the drawable plate and the case body are spliced together; the metal strip cage is arranged on the drawable plate; a partition plate is arranged between every two box bodies, and a through notch from the position of the drawing plate to the top is arranged on the partition plate; the metal strip cages in the two adjacent grid boxes are arranged at diagonal positions. Above-mentioned scheme can guarantee to set for the pull board that the color contrast is high according to laboratory mouse's colour, the validity of shooting when guaranteeing the experiment runs through the breach through the setting and can guarantee to have the activity cheapness of the mouse of putting into the structure, observes the brain activity of mouse and corresponds the relation of action, need not the laboratory staff at any time observe the record, reduces laboratory staff work load.
Description
Technical Field
The utility model belongs to experimental box for the mouse experiments, concretely relates to is an experimental apparatus for studying mouse social behaviors.
Background
Socializing refers to the consciousness of communication between people, information transmission and thought communication in society to achieve certain purpose of social activity. People can only continuously make contact and information communication with various people, and can continuously enrich, develop and expand themselves. For many animals, social importance is also important. Social behavior disorders are a typical feature of many psychiatric disorders, including depression, autism, schizophrenia, and obsessive-compulsive disorder, among others. Therefore, the change of social behavior becomes one of the criteria for judging mental diseases. To study the neurobiological mechanisms of human social behavior disorders, researchers have established many animal models of social behavior deficits. In order to study the changes in social behaviors in animal models, experimenters developed a series of behavioral experiments, of which more mature was social laboratory experiments on large mice.
The social experiment box in the prior art is mostly divided into a plurality of lattices, a simple box body capable of ensuring a small gap for a mouse to pass through is arranged in the middle of the social experiment box, and a box body structure for placing and fixing the mouse is also arranged in the box body, but because the prior art is continuously perfected, a specific electrode/optical fiber is often required to be arranged in a brain, or a small microscope is arranged to study the corresponding relation between the social behavior of the mouse and the brain region activity; because the rear part of the electrode/optical fiber or the miniature microscope structure which is embedded into the mouse is mostly of a long-line structure, the small notch on the box body in the prior art can not ensure that the mouse with the long-line structure can move freely in the box bodies with different grids, and further the research on the relation between the corresponding social behaviors and the brain region activities can not be realized; in the prior art, most of the boxes are fixed and cannot be changed, but the whole process of an experiment is in the shooting and recording process, and in order to research the activities of experimental mice with different colors and different varieties, boxes with different ground colors are generally required to be arranged, so that more boxes are arranged, and the boxes occupy space particularly, so that the whole operation is not convenient; the existing experimental box is designed integrally, the whole box body needs to be cleaned after use, the operation is very complicated, and the workload of workers is increased.
The utility model discloses it is inconvenient to put into structure mouse activity in the brain area that laboratory box exists for mouse social contact in the prior art, and because mouse colour difference need set up a plurality of laboratory boxes, the inconvenient scheduling problem of operation provides an experimental apparatus of research mouse social contact action.
SUMMERY OF THE UTILITY MODEL
In order to overcome among the prior art mouse activity inconvenient, wash difficulty and laboratory box and set up too much scheduling problem, the utility model provides an experimental apparatus of research mouse social behavior.
An experimental apparatus for researching social behaviors of mice comprises a box body with multiple grids and a metal bar cage for fixing the mice, and is characterized in that a long-strip notch is arranged below the front side of each grid box body, a drawable plate is arranged in the long-strip notch, and drawable plates with different colors are arranged in the long-strip notch; when the drawable plate completely extends into each case body, the drawable plate and the case body are spliced together; the metal strip cage is arranged on the drawable plate; a partition plate is arranged between every two box bodies, and a through notch from the position of the drawing plate to the top is arranged on the partition plate; the metal strip cages in the two adjacent grid boxes are arranged at diagonal positions. Above-mentioned setting can guarantee to set for the drawing board of the high specific colour of contrast according to laboratory mouse's colour, the validity of shooting when guaranteeing the experiment runs through the breach through the setting and can guarantee to have the activity cheapness of the mouse of putting into the structure, guarantees the validity of experiment, observes the brain activity of mouse and corresponds the relation of action, need not the experimenter at any time observe the record, reduces the experimenter work load.
Further, but set up the pull board of two kinds of colours of black and white, can stretch into the pull board of different colours in rectangular breach according to the experiment needs.
Further, correspond on the box of rectangular breach opposite side and set up rectangular breach, can guarantee through the mode that sets up corresponding rectangular breach at the offside that can the pull board place in two breach, guarantee the stability of pull board structure.
Further, the length of the drawable plate is consistent with the length of the long notch, and the length of the long notch is equal to the length of the setting side of each box body; the arrangement can ensure the full-area layout of the drawable plate.
Or the length of the drawable plate is consistent with the length of the long strip gap, and the length range of the long strip gap which is smaller than the length range of the setting side of each case body is 3-10 mm; and set up on every check both sides wall that corresponds the height with the board that stretches out of pull board amalgamation, but this kind of setting can guarantee that pull board accounts for most, and then the convenience is observed the correspondence of mouse, and the setting of stretching out the board can realize effectively amalgamating, places dropping of in the experimentation mouse.
Further, the side walls at two sides of the drawable plate are provided with a movable groove for the drawable plate to move; the arrangement of the moving groove can facilitate the movement of the drawing plate, ensure the moving track of the drawing plate and ensure the stability of the drawing plate structure in the moving process.
Furthermore, the drawable plate comprises a front end extending plate and a rear end blocking plate; the blocking plate can effectively block the long notch; the arrangement can effectively prevent the clamping of excrement or the limbs of the mouse.
Furthermore, a handle structure is arranged at the rear end of the blocking plate, so that the operation cheapness is ensured.
Furthermore, a blocking plate arranging groove is formed in the periphery of the blocking plate, the blocking plate is guaranteed to be effectively placed, and the stability of the whole structure is guaranteed.
Further, the barrier plate arrangement groove is formed by a side wall groove or is surrounded by a surrounding plate extending out of the side wall.
Further, the metal strip cage is a cylindrical metal strip cage; the metal column comprises a plurality of metal columns arranged around the middle part, a metal column arrangement ring at the lower part and a metal column arrangement column body at the upper part; the ring is arranged to ensure the aperture of the mouse; the column is set as a solid metal column. The quality of metal strip cage can be effectively guaranteed through the arrangement, the stability of the overall structure of the metal strip cage is further guaranteed, and the problem that the metal strip cage is shaken, inclined and inclined is prevented.
Further, the inner diameter of the setting ring ranges from 90mm to 120 mm; this internal diameter arrangement can ensure effective insertion of the immobilized rat.
Further, the height range of the metal column is 80-90 mm; the height can ensure the effective space for fixing the mouse.
Furthermore, the height of the column body part is set to be 40-60mm, the height setting can guarantee the overall quality and height of the metal strip cage, shaking is prevented, and the moving mouse is effectively prevented from escaping through the metal strip cage.
Furthermore, the bottom of the through notch is square, and the width range is 60-90 mm; with a preferred width range of 80 mm.
Further, the partition plate corner that runs through breach upper portion both sides sets up to fillet structure, and the linear structure on upper portion is hung in the right angle department in order to prevent when the mouse is through running through the breach in the purpose that fillet structure set up, and then leads to the experiment to go on inefficiently.
Furthermore, 4-8 insertion rods are arranged at the bottom of the metal bar cage; in addition, the corresponding insertion holes are formed in the drawable plate, so that the stability of the metal bar cage structure can be further guaranteed, and the situation of falling is prevented.
Or, set up a magnetic layer bottom setting up the ring, but set up the iron sheet structure or will pull the board whole and set up to iron plate in the corresponding position of pull board, through the adsorption of magnetic layer and iron sheet or iron plate, also can play the purpose of effective fixed metal strip cage.
Furthermore, a drawable drawer structure is arranged below the strip notch of the side surface where the drawable plate extends, and the lower part of the drawable plate is communicated with the drawable drawer. This kind of setting can be guaranteed to be through twitching pull board and slope box when the experiment finishes, reaches mouse excrement and urine and finally through the clearance to pull board and pull drawer, accomplishes the clearance to whole experimental box, makes whole clearance process become simple.
Furthermore, the drawable drawer structure is arranged at the bottom of each case, or a large drawable drawer structure is arranged at the bottom of all cases.
Further, when setting up 3 check and above boxes, all set up a drawable drawer at every check bottom half, when setting up 2 check boxes, set up a big drawable drawer that passes through 2 check boxes at the bottom half.
Furthermore, the length range of each case body is 25cm-32 cm; the width range is 20-26 cm; the height range is 18-25 cm;
furthermore, the length of each box body is 28 cm; the width is 24.2 cm; the height is 20cm, and the box body with the size can meet the experiment requirements of most experimental mice.
When the plush mouse is used, the fixing rope is placed in the metal strip cage and is placed on the drawable plate, and the other plush mouse is placed in the contrast metal strip cage to form contrast. Then the social mouse with the electrode is placed in an experimental box, and a drawable plate with a proper color is selected according to the color of the experimental mouse. And finally, observing the behavior of the mouse and the brain region activity of the mouse when the behavior occurs by a control device which is connected with the electrodes through image pickup.
Through the arrangement of the experiment box for the mouse social contact, the technical problems in the prior art can be effectively solved, and through the arrangement of the drawable plates with different colors, the problems that the shooting effect is poor due to the color difference between the bottom of the box body and the color of the experiment mouse, or the operation is frequent when a plurality of experiment boxes are used, and spare experiment boxes are occupied can be effectively solved; in addition, the problem that a mouse with a long line electrode structure can effectively move and the long line cannot be clamped can be effectively solved through the arrangement of the penetrating notch with the round angle at the top end; in addition, the drawable plate is matched with the drawable drawer for use, so that the drawable drawer and the drawable plate can be cleaned to solve the problems of excrement and urine generated by a mouse in the experimental process.
Drawings
Fig. 1 is a schematic view of the overall structure of embodiment 1 of the present invention;
fig. 2 is a schematic view of the overall structure of embodiment 2 of the present invention;
fig. 3 is a schematic view of the overall structure of embodiment 3 of the present invention;
fig. 4 is a schematic view of the overall structure of a cage without a metal strip according to embodiment 3 of the present invention;
fig. 5 is a schematic view of the overall structure of a cage lacking two metal strips according to embodiment 3 of the present invention;
FIG. 6 is a longitudinal sectional view of the drawer of the present invention including only the drawable plate, the drawable drawer and the metal bar cage;
FIG. 7 is a structural view of the case body without the drawable plate and the drawable drawer of the present invention;
FIG. 8 is a longitudinal sectional view of the structure of the drawer without the drawable plate and the drawable drawer of the present invention;
fig. 9 is a schematic view of the whole structure of the cage without the metal strip according to embodiment 4 of the present invention;
fig. 10 is a schematic structural view of a metal strip cage according to embodiment 4 of the present invention;
in the figure, 1, a box body; 2. a metal strip cage; 21. a metal post; 22. setting a ring; 23. arranging a column body; 24. an insertion rod; 25. an insertion hole; 26. a magnetic layer; 27. an iron sheet structure; 3. a strip notch; 4. a drawable plate; 41. a moving groove; 42. extending into the plate; 43. a blocking plate; 44. a handle structure; 45. enclosing plates; 5. a partition plate; 6. penetrating through the notch; 61. a fillet structure; 7. extending the plate; 8. a drawer structure capable of being pulled out.
Detailed Description
Example 1 an experimental apparatus for studying social behaviors of mice
An experimental apparatus for researching social behaviors of mice comprises 2 boxes 1 arranged in grids and a metal bar cage 2 for fixing the mice, wherein a strip notch 3 is arranged below the front side of each box 1, a drawable plate 4 is arranged in the strip notch 3, and drawable plates 4 with different colors are arranged; when the drawable plate 4 is completely inserted into each case 1, the drawable plate 4 and the case 1 are spliced together; the metal strip cage 2 is arranged on the drawable plate 4; a partition plate 5 is arranged between every two box bodies 1, and a through notch 6 from the position of the drawing plate to the top is arranged on the partition plate 5; the metal strip cage 2 is arranged at the diagonal position of the whole box body 1, the maximum separation distance can be guaranteed by the arrangement of the diagonal position, and errors in the experimental process are reduced. Above-mentioned setting can guarantee to set for the drawing board 4 of the high specific colour of contrast according to laboratory mouse's colour, the validity of shooting when guaranteeing the experiment runs through breach 6 through the setting and can guarantee to have the activity cheapness of the mouse of putting into the structure, guarantees the validity of experiment, observes the brain activity of mouse and corresponds the relation of action, need not the experimenter at any time observe the record, reduces the experimenter work load. But set up the pull board 4 of two kinds of colours of black and white, can stretch into the pull board 4 of different colours in rectangular breach 3 according to the experiment needs.
Correspond on the box 1 of 3 opposite sides of rectangular breach and set up rectangular breach 3, can guarantee through the mode that sets up corresponding rectangular breach 3 at the offside that can pull board 4 places in two breachs, guarantee the stability of 4 structures of pull board. The length of the drawable plate 4 is consistent with the length of the long gap 3, and the length range of the long gap 3 which is less than the length of the setting side of each case 1 is 3-10 mm; and set up on every check both sides wall that corresponds the height with the board 7 that stretches out of 4 amalgamations of pull board, but this kind of setting can guarantee that pull board 4 accounts for most, and then the convenience is observed the correspondence of mouse, and the setting of stretching out board 7 can realize effectively amalgamation, places dropping of mouse in the experimentation.
The drawable plate 4 comprises a front end extending plate 42 and a rear end blocking plate 43; the blocking plate 43 can effectively block the long gap 3; the arrangement can effectively prevent the clamping of excrement or the limbs of the mouse. A handle structure 44 is provided at the rear end of the blocking plate 43 to ensure the cheapness of the operation. Set up the barrier plate 43 and set up the groove in the periphery of barrier plate 43, guarantee that barrier plate 43 effectively places, and guarantee the stability of whole structure. The blocking plate 43 is provided with a slot constituted by a recess in the side wall or by a collar 45 protruding from the side wall.
The metal strip cage 2 is a cylindrical metal strip cage 2; a plurality of metal columns 21 surrounding the middle part, a ring 22 arranged on the lower part of the metal column 21, and a column 23 arranged on the upper part of the metal column 21; the setting ring 22 is provided with a caliber for ensuring the placement of the mouse; the column 23 is provided as a solid metal column 21. This kind of setting can effectively guarantee the quality of metal strip cage 2, and then guarantees metal strip cage 2 overall structure's stability, prevents to take place to rock the askew problem of slope.
The inner diameter of the setting ring 22 ranges from 90mm to 120 mm; this internal diameter arrangement can ensure effective insertion of the immobilized rat. The height range of the metal column 21 is 80-90 mm; the height can ensure the effective space for fixing the mouse. The height of the column 23 is 40-60mm, and the height arrangement can ensure the overall quality and height of the metal strip cage 2, prevent shaking and effectively prevent a moving mouse from escaping through the metal strip cage 2.
The bottom of the through notch 6 is square, and the width range is 60-90 mm; with a preferred width range of 80 mm. The 5 angles of the partition plate, which run through the two sides of the upper part of the notch 6, are set to be the fillet structures 61, and the purpose of the fillet structures 61 is to prevent the linear structures on the upper part of the mouse from being hung at the right angles when the mouse passes through the notch 6, so that the experiment cannot be carried out. The length of each case 1 is 28 cm; the width is 24.2 cm; the height is 20cm, and the box body 1 with the size can meet the experiment requirements of most experimental mice
Example 2 an experimental apparatus for studying social behaviors of mice
An experimental apparatus for researching social behaviors of mice comprises 2 boxes 1 arranged in grids and a metal bar cage 2 for fixing the mice, wherein a strip notch 3 is arranged below the front side of each box 1, a drawable plate 4 is arranged in the strip notch 3, and drawable plates 4 with different colors are arranged; when the drawable plate 4 is completely inserted into each case 1, the drawable plate 4 and the case 1 are spliced together; the metal strip cage 2 is arranged on the drawable plate 4; a partition plate 5 is arranged between every two box bodies 1, and a through notch 6 from the position of the drawing plate to the top is arranged on the partition plate 5; the metal strip cage 2 is arranged at the diagonal position of the whole box body 1, the maximum separation distance can be guaranteed by the arrangement of the diagonal position, and errors in the experimental process are reduced. Above-mentioned setting can guarantee to set for the drawing board 4 of the high specific colour of contrast according to laboratory mouse's colour, the validity of shooting when guaranteeing the experiment runs through breach 6 through the setting and can guarantee to have the activity cheapness of the mouse of putting into the structure, guarantees the validity of experiment, observes the brain activity of mouse and corresponds the relation of action, need not the experimenter at any time observe the record, reduces the experimenter work load. But set up the pull board 4 of two kinds of colours of black and white, can stretch into the pull board 4 of different colours in rectangular breach 3 according to the experiment needs.
Correspond on the box 1 of 3 opposite sides of rectangular breach and set up rectangular breach 3, can guarantee through the mode that sets up corresponding rectangular breach 3 at the offside that can pull board 4 places in two breachs, guarantee the stability of 4 structures of pull board. The length of the drawable plate 4 is consistent with the length of the long gap 3, and the length of the long gap 3 is equal to the length of the setting side of each case 1; this arrangement ensures the full area layout of the drawable plate 4.
The side walls at two sides of the drawable plate 4 are provided with a moving groove 41 for the drawable plate 4 to move; the arrangement of the moving groove 41 can facilitate the movement of the drawing plate, and ensure the moving track of the drawing plate 4 and the stability of the structure of the drawing plate 4 in the moving process.
The drawable plate 4 comprises a front end extending plate 42 and a rear end blocking plate 43; the blocking plate 43 can effectively block the long gap 3; the arrangement can effectively prevent the clamping of excrement or the limbs of the mouse. A handle structure 44 is provided at the rear end of the blocking plate 43 to ensure the cheapness of the operation. Set up the barrier plate 43 and set up the groove in the periphery of barrier plate 43, guarantee that barrier plate 43 effectively places, and guarantee the stability of whole structure. The blocking plate 43 is provided with a slot constituted by a recess in the side wall or by a collar 45 protruding from the side wall.
The metal strip cage 2 is a cylindrical metal strip cage 2; a plurality of metal columns 21 surrounding the middle part, a ring 22 arranged on the lower part of the metal column 21, and a column 23 arranged on the upper part of the metal column 21; the setting ring 22 is provided with a caliber for ensuring the placement of the mouse; the column 23 is provided as a solid metal column 21. This kind of setting can effectively guarantee the quality of metal strip cage 2, and then guarantees metal strip cage 2 overall structure's stability, prevents to take place to rock the askew problem of slope.
The inner diameter of the setting ring 22 ranges from 90mm to 120 mm; this internal diameter arrangement can ensure effective insertion of the immobilized rat. The height range of the metal column 21 is 80-90 mm; the height can ensure the effective space for fixing the mouse. The height of the column 23 is 40-60mm, and the height arrangement can ensure the overall quality and height of the metal strip cage 2, prevent shaking and effectively prevent a moving mouse from escaping through the metal strip cage 2.
The bottom of the through notch 6 is square, and the width range is 60-90 mm; with a preferred width range of 80 mm. The 5 angles of the partition plate, which run through the two sides of the upper part of the notch 6, are set to be the fillet structures 61, and the purpose of the fillet structures 61 is to prevent the linear structures on the upper part of the mouse from being hung at the right angles when the mouse passes through the notch 6, so that the experiment cannot be carried out.
A drawable drawer structure 8 is arranged below the strip notch 3 of the side surface where the drawable plate 4 extends, and the lower part of the drawable plate 4 is communicated with the drawable drawer. This kind of setting can be guaranteed to be through twitching pull board 4 and slope box 1 when the experiment finishes, reaches mouse excrement and urine and finally through the clearance to pull board 4 and pull drawer, accomplishes the clearance to whole experimental box, makes whole clearance process become simple. A large drawer structure 8 is provided at the bottom of all the cases 1. The length of each case 1 is 28 cm; the width is 24.2 cm; the height is 20cm, and the box body 1 with the size can meet the experiment requirements of most experimental mice.
Example 3 an experimental apparatus for studying social behaviors of mice
An experimental apparatus for researching social behaviors of mice comprises 2 boxes 1 arranged in grids and a metal bar cage 2 for fixing the mice, wherein a strip notch 3 is arranged below the front side of each box 1, a drawable plate 4 is arranged in the strip notch 3, and drawable plates 4 with different colors are arranged; when the drawable plate 4 is completely inserted into each case 1, the drawable plate 4 and the case 1 are spliced together; the metal strip cage 2 is arranged on the drawable plate 4; a partition plate 5 is arranged between every two box bodies 1, and a through notch 6 from the position of the drawing plate to the top is arranged on the partition plate 5; the metal strip cage 2 is arranged at the diagonal position of the whole box body 1, the maximum separation distance can be guaranteed by the arrangement of the diagonal position, and errors in the experimental process are reduced. Above-mentioned setting can guarantee to set for the drawing board 4 of the high specific colour of contrast according to laboratory mouse's colour, the validity of shooting when guaranteeing the experiment runs through breach 6 through the setting and can guarantee to have the activity cheapness of the mouse of putting into the structure, guarantees the validity of experiment, observes the brain activity of mouse and corresponds the relation of action, need not the experimenter at any time observe the record, reduces the experimenter work load. But set up the pull board 4 of two kinds of colours of black and white, can stretch into the pull board 4 of different colours in rectangular breach 3 according to the experiment needs.
Correspond on the box 1 of 3 opposite sides of rectangular breach and set up rectangular breach 3, can guarantee through the mode that sets up corresponding rectangular breach 3 at the offside that can pull board 4 places in two breachs, guarantee the stability of 4 structures of pull board.
The length of the drawable plate 4 is consistent with the length of the long gap 3, and the length of the long gap 3 is equal to the length of the setting side of each case 1; this arrangement ensures the full area layout of the drawable plate 4.
The side walls at two sides of the drawable plate 4 are provided with a moving groove 41 for the drawable plate 4 to move; the arrangement of the moving groove 41 can facilitate the movement of the drawing plate, and ensure the moving track of the drawing plate 4 and the stability of the structure of the drawing plate 4 in the moving process.
The drawable plate 4 comprises a front end extending plate 42 and a rear end blocking plate 43; the blocking plate 43 can effectively block the long gap 3; the arrangement can effectively prevent the clamping of excrement or the limbs of the mouse. A handle structure 44 is provided at the rear end of the blocking plate 43 to ensure the cheapness of the operation. Set up the barrier plate 43 and set up the groove in the periphery of barrier plate 43, guarantee that barrier plate 43 effectively places, and guarantee the stability of whole structure. The blocking plate 43 is provided with a slot constituted by a recess in the side wall or by a collar 45 protruding from the side wall.
The metal strip cage 2 is a cylindrical metal strip cage 2; a plurality of metal columns 21 surrounding the middle part, a ring 22 arranged on the lower part of the metal column 21, and a column 23 arranged on the upper part of the metal column 21; the setting ring 22 is provided with a caliber for ensuring the placement of the mouse; the column 23 is provided as a solid metal column 21. This kind of setting can effectively guarantee the quality of metal strip cage 2, and then guarantees metal strip cage 2 overall structure's stability, prevents to take place to rock the askew problem of slope.
The inner diameter of the setting ring 22 ranges from 90mm to 120 mm; this internal diameter arrangement can ensure effective insertion of the immobilized rat. The height range of the metal column 21 is 80-90 mm; the height can ensure the effective space for fixing the mouse. The height of the column 23 is 40-60mm, and the height arrangement can ensure the overall quality and height of the metal strip cage 2, prevent shaking and effectively prevent a moving mouse from escaping through the metal strip cage 2.
The bottom of the through notch 6 is square, and the width range is 60-90 mm; with a preferred width range of 80 mm. The 5 angles of the partition plate, which run through the two sides of the upper part of the notch 6, are set to be the fillet structures 61, and the purpose of the fillet structures 61 is to prevent the linear structures on the upper part of the mouse from being hung at the right angles when the mouse passes through the notch 6, so that the experiment cannot be carried out.
4-8 insertion rods 24 are arranged at the bottom of the metal strip cage 2; in addition, the drawable plate 4 is provided with corresponding insertion holes 25, so that the stability of the metal bar cage 2 structure can be further ensured, and the phenomenon of toppling can be prevented.
The bottom of all the box bodies 1 is provided with a large drawable drawer structure 8, and the lower part of the drawable plate 4 is communicated with the drawable drawer for the drawable drawer structure 8 arranged below the strip notch 3 on the side surface into which the drawable plate 4 extends. This kind of setting can be guaranteed to be through twitching pull board 4 and slope box 1 when the experiment finishes, reaches mouse excrement and urine and finally through the clearance to pull board 4 and pull drawer, accomplishes the clearance to whole experimental box, makes whole clearance process become simple. The length of each case 1 is 28 cm; the width is 24.2 cm; the height is 20cm, and the box body 1 with the size can meet the experiment requirements of most experimental mice.
Example 4 an experimental apparatus for studying social behaviors of mice
An experimental apparatus for researching social behaviors of mice comprises 2 boxes 1 arranged in grids and a metal bar cage 2 for fixing the mice, wherein a strip notch 3 is arranged below the front side of each box 1, a drawable plate 4 is arranged in the strip notch 3, and drawable plates 4 with different colors are arranged; when the drawable plate 4 is completely inserted into each case 1, the drawable plate 4 and the case 1 are spliced together; the metal strip cage 2 is arranged on the drawable plate 4; a partition plate 5 is arranged between every two box bodies 1, and a through notch 6 from the position of the drawing plate to the top is arranged on the partition plate 5; the metal strip cage 2 is arranged at the diagonal position of the whole box body 1, the maximum separation distance can be guaranteed by the arrangement of the diagonal position, and errors in the experimental process are reduced. Above-mentioned setting can guarantee to set for the drawing board 4 of the high specific colour of contrast according to laboratory mouse's colour, the validity of shooting when guaranteeing the experiment runs through breach 6 through the setting and can guarantee to have the activity cheapness of the mouse of putting into the structure, guarantees the validity of experiment, observes the brain activity of mouse and corresponds the relation of action, need not the experimenter at any time observe the record, reduces the experimenter work load. But set up the pull board 4 of two kinds of colours of black and white, can stretch into the pull board 4 of different colours in rectangular breach 3 according to the experiment needs.
Correspond on the box 1 of 3 opposite sides of rectangular breach and set up rectangular breach 3, can guarantee through the mode that sets up corresponding rectangular breach 3 at the offside that can pull board 4 places in two breachs, guarantee the stability of 4 structures of pull board. The length of the drawable plate 4 is consistent with the length of the long gap 3, and the length of the long gap 3 is equal to the length of the setting side of each case 1; this arrangement ensures the full area layout of the drawable plate 4.
The side walls at two sides of the drawable plate 4 are provided with a moving groove 41 for the drawable plate 4 to move; the arrangement of the moving groove 41 can facilitate the movement of the drawing plate, and ensure the moving track of the drawing plate 4 and the stability of the structure of the drawing plate 4 in the moving process.
The drawable plate 4 comprises a front end extending plate 42 and a rear end blocking plate 43; the blocking plate 43 can effectively block the long gap 3; the arrangement can effectively prevent the clamping of excrement or the limbs of the mouse. A handle structure 44 is provided at the rear end of the blocking plate 43 to ensure the cheapness of the operation. Set up the barrier plate 43 and set up the groove in the periphery of barrier plate 43, guarantee that barrier plate 43 effectively places, and guarantee the stability of whole structure. The blocking plate 43 is provided with a slot constituted by a recess in the side wall or by a collar 45 protruding from the side wall.
The metal strip cage 2 is a cylindrical metal strip cage 2; a plurality of metal columns 21 surrounding the middle part, a ring 22 arranged on the lower part of the metal column 21, and a column 23 arranged on the upper part of the metal column 21; setting ring 22
Setting a caliber for ensuring the placement of the mouse; the column 23 is provided as a solid metal column 21. This kind of setting can effectively guarantee the quality of metal strip cage 2, and then guarantees metal strip cage 2 overall structure's stability, prevents to take place to rock the askew problem of slope.
The inner diameter of the setting ring 22 ranges from 90mm to 120 mm; this internal diameter arrangement can ensure effective insertion of the immobilized rat. The height range of the metal column 21 is 80-90 mm; the height can ensure the effective space for fixing the mouse. The height of the column 23 is 40-60mm, and the height arrangement can ensure the overall quality and height of the metal strip cage 2, prevent shaking and effectively prevent a moving mouse from escaping through the metal strip cage 2.
The bottom of the through notch 6 is square, and the width range is 60-90 mm; with a preferred width range of 80 mm. The 5 angles of the partition plate, which run through the two sides of the upper part of the notch 6, are set to be the fillet structures 61, and the purpose of the fillet structures 61 is to prevent the linear structures on the upper part of the mouse from being hung at the right angles when the mouse passes through the notch 6, so that the experiment cannot be carried out.
Set up a magnetic layer 26 in setting up ring 22 bottom, set up iron sheet structure 27 or will pull the board 4 wholly to set up to iron plate in the corresponding position of the board 4 that can pull, through the adsorption of magnetic layer 26 and iron sheet or iron plate, also can play the purpose of effectively fixed metal strip cage 2.
The bottom of all the box bodies 1 is provided with a large drawable drawer structure 8, and the lower part of the drawable plate 4 is communicated with the drawable drawer for the drawable drawer structure 8 arranged below the strip notch 3 on the side surface into which the drawable plate 4 extends. This kind of setting can be guaranteed to be through twitching pull board 4 and slope box 1 when the experiment finishes, reaches mouse excrement and urine and finally through the clearance to pull board 4 and pull drawer, accomplishes the clearance to whole experimental box, makes whole clearance process become simple. The length of each case 1 is 28 cm; the width is 24.2 cm; the height is 20cm, and the box body 1 with the size can meet the experiment requirements of most experimental mice.
Example 5 an experimental apparatus for studying social behaviors of mice
An experimental apparatus for researching social behaviors of mice comprises 3 cases 1 and a metal bar cage 2 for fixing the mice, wherein a strip notch 3 is arranged below the front side of each case 1, a drawable plate 4 is arranged in the strip notch 3, and drawable plates 4 with different colors are arranged; when the drawable plate 4 is completely inserted into each case 1, the drawable plate 4 and the case 1 are spliced together; the metal strip cage 2 is arranged on the drawable plate 4; a partition plate 5 is arranged between every two box bodies 1, and a through notch 6 from the position of the drawing plate to the top is arranged on the partition plate 5; the metal strip cage 2 is arranged at the diagonal position of each two adjacent box bodies 1, the maximum separation distance can be ensured by the arrangement of the diagonal position, and errors in the experimental process are reduced. Above-mentioned setting can guarantee to set for the drawing board 4 of the high specific colour of contrast according to laboratory mouse's colour, the validity of shooting when guaranteeing the experiment runs through breach 6 through the setting and can guarantee to have the activity cheapness of the mouse of putting into the structure, guarantees the validity of experiment, observes the brain activity of mouse and corresponds the relation of action, need not the experimenter at any time observe the record, reduces the experimenter work load. But set up the pull board 4 of two kinds of colours of black and white, can stretch into the pull board 4 of different colours in rectangular breach 3 according to the experiment needs.
Correspond on the box 1 of 3 opposite sides of rectangular breach and set up rectangular breach 3, can guarantee through the mode that sets up corresponding rectangular breach 3 at the offside that can pull board 4 places in two breachs, guarantee the stability of 4 structures of pull board.
The length of the drawable plate 4 is consistent with the length of the long gap 3, and the length of the long gap 3 is equal to the length of the setting side of each case 1; this arrangement ensures the full area layout of the drawable plate 4.
The side walls at two sides of the drawable plate 4 are provided with a moving groove 41 for the drawable plate 4 to move; the arrangement of the moving groove 41 can facilitate the movement of the drawing plate, and ensure the moving track of the drawing plate 4 and the stability of the structure of the drawing plate 4 in the moving process.
The drawable plate 4 comprises a front end extending plate 42 and a rear end blocking plate 43; the blocking plate 43 can effectively block the long gap 3; the arrangement can effectively prevent the clamping of excrement or the limbs of the mouse. A handle structure 44 is provided at the rear end of the blocking plate 43 to ensure the cheapness of the operation. Set up the barrier plate 43 and set up the groove in the periphery of barrier plate 43, guarantee that barrier plate 43 effectively places, and guarantee the stability of whole structure. The blocking plate 43 is provided with a slot constituted by a recess in the side wall or by a collar 45 protruding from the side wall.
The metal strip cage 2 is a cylindrical metal strip cage 2; a plurality of metal columns 21 surrounding the middle part, a ring 22 arranged on the lower part of the metal column 21, and a column 23 arranged on the upper part of the metal column 21; the setting ring 22 is provided with a caliber for ensuring the placement of the mouse; the column 23 is provided as a solid metal column 21. This kind of setting can effectively guarantee the quality of metal strip cage 2, and then guarantees metal strip cage 2 overall structure's stability, prevents to take place to rock the askew problem of slope.
The inner diameter of the setting ring 22 ranges from 90mm to 120 mm; this internal diameter arrangement can ensure effective insertion of the immobilized rat. The height range of the metal column 21 is 80-90 mm; the height can ensure the effective space for fixing the mouse. The height of the column 23 is 40-60mm, and the height arrangement can ensure the overall quality and height of the metal strip cage 2, prevent shaking and effectively prevent a moving mouse from escaping through the metal strip cage 2.
The bottom of the through notch 6 is square, and the width range is 60-90 mm; with a preferred width range of 80 mm. The 5 angles of the partition plate, which run through the two sides of the upper part of the notch 6, are set to be the fillet structures 61, and the purpose of the fillet structures 61 is to prevent the linear structures on the upper part of the mouse from being hung at the right angles when the mouse passes through the notch 6, so that the experiment cannot be carried out.
Set up a magnetic layer 26 in setting up ring 22 bottom, set up iron sheet structure 27 or will pull the board 4 wholly to set up to iron plate in the corresponding position of the board 4 that can pull, through the adsorption of magnetic layer 26 and iron sheet or iron plate, also can play the purpose of effectively fixed metal strip cage 2.
In every check box 1, but set up a pull drawer structure 8 below the rectangular breach 3 of the side that can pull board 4 stretched into, but pull board 4 below link up with the pull drawer, but pull drawer structure 8 sets up in every check box 1 bottom. This kind of setting can be guaranteed to be through twitching pull board 4 and slope box 1 when the experiment finishes, reaches mouse excrement and urine and finally through the clearance to pull board 4 and pull drawer, accomplishes the clearance to whole experimental box, makes whole clearance process become simple. The length of each case 1 is 28 cm; the width is 24.2 cm; the height is 20cm, and the box body 1 with the size can meet the experiment requirements of most experimental mice.
The above description of the embodiments is only intended to illustrate the present invention. It should be noted that, for those skilled in the art, without departing from the principle of the present invention, several modifications can be made to the present invention, and these modifications will fall within the protection scope of the claims of the present invention.
Claims (10)
1. An experimental apparatus for researching social behaviors of mice comprises a box body (1) with multiple grids and a metal bar cage (2) for fixing the mice, and is characterized in that a strip-shaped notch (3) is arranged below the front side of each grid of the box body (1), a drawable plate (4) is arranged in the strip-shaped notch (3), and drawable plates (4) with different colors are arranged; when the drawable plate (4) is completely stretched into each case of the box body (1), the drawable plate (4) and the box body (1) are spliced together; the metal strip cage (2) is arranged on the drawable plate (4); a partition plate (5) is arranged between every two box bodies (1), and a through notch (6) from the position of the drawing plate to the top is arranged on the partition plate (5); the metal strip cages (2) in the two adjacent box bodies (1) are arranged at diagonal positions.
2. The experimental facility for studying social behaviors of mice according to claim 1, wherein the elongated notch (3) is correspondingly formed on the box body (1) at the other side of the elongated notch (3).
3. Experimental apparatus for studying social behaviour in mice according to claim 2, characterised in that the length of the extractable plate (4) is identical to the length of the elongated notch (3), the length of the elongated notch (3) being equal to the length of the side of each case (1) on which it is arranged.
4. The experimental facility for studying social behaviors of mice according to claim 3, wherein the side walls of both sides of the drawable plate (4) are provided with moving grooves (41) for moving the drawable plate (4).
5. Experimental apparatus for studying social behaviour in mice according to claim 1, characterised in that said extractable plate (4) comprises a front end access plate (42) and a rear end blocking plate (43).
6. Experimental apparatus for studying social behaviour in mice according to claim 1, characterised in that the metal strip cage (2) is a cylindrical metal strip cage (2); comprises a plurality of metal columns (21) arranged around the middle part, a ring (22) arranged on the lower part of the metal column (21) and a column (23) arranged on the upper part of the metal column (21); the setting ring (22) is provided with a caliber for ensuring the placement of a mouse; the column (23) is a solid metal column (21).
7. Experimental apparatus for studying social behaviour in mice according to claim 6, characterised in that the inner diameter of the setting ring (22) ranges from 90mm to 120 mm.
8. Experimental apparatus for studying social behaviour in mice according to claim 6, characterised in that the height of the portion of the column (23) is 40-60 mm.
9. Experimental apparatus for studying social behaviour in mice according to any one of claims 1 to 8, characterised in that the bottom of the through-going gap (6) is square and has a width in the range of 60-90 mm.
10. Experimental apparatus for studying social behaviour in mice according to claim 9, characterised in that the corners of the spacer (5) on both sides of the upper part of the through-cut (6) are provided with rounded corner structures (61).
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| CN201921240649.5U CN210352656U (en) | 2019-08-02 | 2019-08-02 | Experimental apparatus for researching social behaviors of mice |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110301364A (en) * | 2019-08-02 | 2019-10-08 | 中国人民解放军军事科学院军事医学研究院 | Experimental box is used in a kind of research of mouse Social behaviors |
| CN112237156A (en) * | 2020-10-23 | 2021-01-19 | 宁波大学 | Device and experimental method for testing autonomous social behaviors of small animals |
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2019
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110301364A (en) * | 2019-08-02 | 2019-10-08 | 中国人民解放军军事科学院军事医学研究院 | Experimental box is used in a kind of research of mouse Social behaviors |
| CN110301364B (en) * | 2019-08-02 | 2021-09-24 | 中国人民解放军军事科学院军事医学研究院 | Experiment box for research on social behaviors of mice |
| CN112237156A (en) * | 2020-10-23 | 2021-01-19 | 宁波大学 | Device and experimental method for testing autonomous social behaviors of small animals |
| CN112237156B (en) * | 2020-10-23 | 2022-07-22 | 宁波大学 | Autonomous social behavior testing device and experimental method for small animals |
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